Gaetano Thiene

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. doi request reprint Diagnostic use of the endomyocardial biopsy: a consensus statement
    Gaetano Thiene
    Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Via A Gabelli, 61, 35121 Padua, Italy
    Virchows Arch 463:1-5. 2013
  2. ncbi request reprint Arrhythmogenic right ventricular cardiomyopathy. What is needed for a cure?
    G Thiene
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
    Herz 37:657-62. 2012
  3. doi request reprint Arrhythmogenic cardiomyopathy: from autopsy to genes and transgenic mice (SCVP Achievement Award Lecture, San Antonio, TX, February 27, 2011)
    Gaetano Thiene
    Cardiovascular Pathology, Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 21:229-39. 2012
  4. doi request reprint Why and how to support screening strategies to prevent sudden death in athletes
    Gaetano Thiene
    University of Padua Medical School, Italy
    Cell Tissue Res 348:315-8. 2012
  5. pmc Cardiac involvement in patients with Becker muscular dystrophy: new diagnostic and pathophysiological insights by a CMR approach
    Ali Yilmaz
    Division of Cardiology, Robert Bosch Krankenhaus, Stuttgart, Germany
    J Cardiovasc Magn Reson 10:50. 2008
  6. pmc Missense mutations in desmocollin-2 N-terminus, associated with arrhythmogenic right ventricular cardiomyopathy, affect intracellular localization of desmocollin-2 in vitro
    Giorgia Beffagna
    Department of Biology, University of Padua, Padua, Italy
    BMC Med Genet 8:65. 2007
  7. doi request reprint Anatomical and pathophysiological classification of congenital heart disease
    Gaetano Thiene
    Department of Medico Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 19:259-74. 2010
  8. doi request reprint AECVP and SCVP 2009 recommendations for training in cardiovascular pathology
    Gaetano Thiene
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Via A Gabelli 61, 35121 Padova, Italy
    Cardiovasc Pathol 19:129-35. 2010
  9. ncbi request reprint Anticalcification strategies to increase bioprosthetic valve durability
    Gaetano Thiene
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    J Heart Valve Dis 20:37-44. 2011
  10. doi request reprint Myocardial infarction: a paradigm of success in modern medicine
    Gaetano Thiene
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 19:1-5. 2010

Detail Information

Publications146 found, 100 shown here

  1. doi request reprint Diagnostic use of the endomyocardial biopsy: a consensus statement
    Gaetano Thiene
    Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Via A Gabelli, 61, 35121 Padua, Italy
    Virchows Arch 463:1-5. 2013
    ..Optimal use of the endomyocardial biopsy requires clinicopathologic correlations...
  2. ncbi request reprint Arrhythmogenic right ventricular cardiomyopathy. What is needed for a cure?
    G Thiene
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
    Herz 37:657-62. 2012
    ....
  3. doi request reprint Arrhythmogenic cardiomyopathy: from autopsy to genes and transgenic mice (SCVP Achievement Award Lecture, San Antonio, TX, February 27, 2011)
    Gaetano Thiene
    Cardiovascular Pathology, Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 21:229-39. 2012
    ..Cardiomyocyte cell death occurs with time as a genetically determined injury. The challenge now is to find ways to prevent onset and progression of the disease...
  4. doi request reprint Why and how to support screening strategies to prevent sudden death in athletes
    Gaetano Thiene
    University of Padua Medical School, Italy
    Cell Tissue Res 348:315-8. 2012
    ..The employment of these tools at pre-participation screening can help to identify concealed anomalies, which may play a major role in early diagnosis, risk stratification, and prevention of sudden death...
  5. pmc Cardiac involvement in patients with Becker muscular dystrophy: new diagnostic and pathophysiological insights by a CMR approach
    Ali Yilmaz
    Division of Cardiology, Robert Bosch Krankenhaus, Stuttgart, Germany
    J Cardiovasc Magn Reson 10:50. 2008
    ..Cardiovascular magnetic resonance (CMR) has the potential to detect cardiac involvement by depicting early scar formation that may appear before onset of wall motion abnormalities...
  6. pmc Missense mutations in desmocollin-2 N-terminus, associated with arrhythmogenic right ventricular cardiomyopathy, affect intracellular localization of desmocollin-2 in vitro
    Giorgia Beffagna
    Department of Biology, University of Padua, Padua, Italy
    BMC Med Genet 8:65. 2007
    ..We screened 54 ARVC probands for mutations in desmocollin-2 (DSC2), the only desmocollin isoform expressed in cardiac tissue...
  7. doi request reprint Anatomical and pathophysiological classification of congenital heart disease
    Gaetano Thiene
    Department of Medico Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 19:259-74. 2010
    ....
  8. doi request reprint AECVP and SCVP 2009 recommendations for training in cardiovascular pathology
    Gaetano Thiene
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Via A Gabelli 61, 35121 Padova, Italy
    Cardiovasc Pathol 19:129-35. 2010
    ..It includes a detailed curriculum and describes three levels of expertise that can be developed...
  9. ncbi request reprint Anticalcification strategies to increase bioprosthetic valve durability
    Gaetano Thiene
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    J Heart Valve Dis 20:37-44. 2011
    ..However, whilst this situation is the reverse of that during the 1990s, the question must be asked as to whether this is simply a fluctuating fashion, or a reflection of other factors...
  10. doi request reprint Myocardial infarction: a paradigm of success in modern medicine
    Gaetano Thiene
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 19:1-5. 2010
    ..The achievements in its prevention, diagnosis, and treatment should be considered as a pride of cardiovascular medicine...
  11. doi request reprint Prevention of sudden cardiac death in the young and in athletes: dream or reality?
    Gaetano Thiene
    Pathology Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 19:207-17. 2010
    ..Genetic screening could play a pivotal role in early detection of asymptomatic mutation carriers of cardiovascular diseases at risk of SD...
  12. pmc Arrhythmogenic right ventricular cardiomyopathy/dysplasia
    Gaetano Thiene
    Pathological Anatomy, Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Orphanet J Rare Dis 2:45. 2007
    ..Preparticipation screening for sport eligibility has been proven to be effective in detecting asymptomatic patients and sport disqualification has been life-saving, substantially declining sudden death in young athletes...
  13. doi request reprint Three-dimensional electroanatomical voltage mapping and histologic evaluation of myocardial substrate in right ventricular outflow tract tachycardia
    Domenico Corrado
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Padua, Italy
    J Am Coll Cardiol 51:731-9. 2008
    ....
  14. ncbi request reprint Intermediate results of isolated mitral valve replacement with a Biocor porcine valve
    Giulio Rizzoli
    Department of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy
    J Thorac Cardiovasc Surg 129:322-9. 2005
    ..We analyzed the intermediate experience, survival, and prosthetic complications of patients who received the Biocor valve, a new-generation porcine valve, in the mitral position...
  15. doi request reprint Acute biopsy-proven lymphocytic myocarditis mimicking Takotsubo cardiomyopathy
    Alida L P Caforio
    Department of Cardiological, Thoracic and Vascular Sciences, University of Padova Policlinico, Via Giustiniani, 2, 35128 Padova, Italy
    Eur J Heart Fail 11:428-31. 2009
    ..Since myocarditis can mimic acute myocardial infarction with normal coronary arteries, EMB should be performed to rule out myocarditis in patients presenting with LV apical ballooning syndrome (or Takotsubo cardiomyopathy)...
  16. pmc Clinical phenotype and diagnosis of arrhythmogenic right ventricular cardiomyopathy in pediatric patients carrying desmosomal gene mutations
    Barbara Bauce
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
    Heart Rhythm 8:1686-95. 2011
    ..Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease carrying a risk of sudden death. Information about the clinical features during childhood and the age at disease onset is scanty...
  17. ncbi request reprint Continuous engraftment and differentiation of male recipient Y-chromosome-positive cardiomyocytes in donor female human heart transplants
    Annalisa Angelini
    Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    J Heart Lung Transplant 26:1110-8. 2007
    ..The possible mechanisms by which stem cells acquire a cardiac phenotypic lineage were also investigated...
  18. doi request reprint Can C4d immunostaining on endomyocardial biopsies be considered a prognostic biomarker in heart transplant recipients?
    Marny Fedrigo
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
    Transplantation 90:791-8. 2010
    ..The aim of this study was to assess the significance of positive C4d capillary immunostaining of endomyocardial biopsies and its correlation to clinical outcome in adult heart transplant recipients...
  19. pmc Follow-up with exercise test of effort-induced ventricular arrhythmias linked to ryanodine receptor type 2 gene mutations
    Alexandros Klavdios Steriotis
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Italy
    Am J Cardiol 109:1015-9. 2012
    ....
  20. doi request reprint Role of morphologic parameters on endomyocardial biopsy to detect sub-clinical antibody-mediated rejection in heart transplantation
    Marny Fedrigo
    Department of Medico Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
    J Heart Lung Transplant 30:1381-8. 2011
    ..The present study evaluated if morphologic parameters detect signs of early sub-clinical or latent stages of antibody-mediated rejection (AMR) and their correlation with C4d staining in cardiac transplants recipients...
  21. ncbi request reprint Hemodynamic and clinical outcomes with the Biocor valve in the aortic position: an 8-year experience
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Padua
    J Thorac Cardiovasc Surg 127:1616-23. 2004
    ..The aim of this study was to analyze the 8-year experience, survival, prosthetic complications, and hemodynamics of patients who received the Biocor valve, a new-generation tissue valve, in the aortic position...
  22. ncbi request reprint Biological versus mechanical aortic prosthesis? A nineteen-year comparison in a propensity-matched population
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy
    J Heart Valve Dis 14:493-500. 2005
    ....
  23. ncbi request reprint Prognostic value of endocardial voltage mapping in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia
    Federico Migliore
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padova, Medical School, Padova, Italy
    Circ Arrhythm Electrophysiol 6:167-76. 2013
    ..We prospectively assessed the prognostic value of EVM in a consecutive series of patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D)...
  24. pmc Desmin mutations and arrhythmogenic right ventricular cardiomyopathy
    Alessandra Lorenzon
    Department of Biology, University of Padua, Italy
    Am J Cardiol 111:400-5. 2013
    ..These findings have important implications in the mutation screening strategy for patients with ARVC...
  25. doi request reprint Arrhythmogenic right ventricular cardiomyopathy
    Cristina Basso
    University of Padua Medical School, Padua, Italy
    Lancet 373:1289-300. 2009
    ..Cascade genetic screening of family members of gene-positive probands allows the identification of asymptomatic carriers who would require lifelong follow-up due to the age-related penetrance...
  26. ncbi request reprint Antibody-mediated rejection without acute graft dysfunction in adult ABO-compatible heart transplantation: a case of accommodation
    Annalisa Angelini
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    J Heart Lung Transplant 27:1357-60. 2008
    ..Physicians should be aware of the accommodation phenomenon so they can identify this subset of patients and assess its long-term effects on chronic rejection and outcome in transplanted patients...
  27. ncbi request reprint The experience with porcine bioprostheses at Padua University
    Gino Gerosa
    Department of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy
    J Heart Valve Dis 13:S44-8. 2004
  28. ncbi request reprint Ureteral stenosis in HDAF pig-to-primate renal xenotransplantation: a phenomenon related to immunological events?
    Nicola Baldan
    Padua General Hospital, Padua, Italy
    Am J Transplant 4:475-81. 2004
    ..Use of a ureteral stent extends the survival of a xenografted primate, thereby helping to clarify the immunological events surrounding the onset of AHXR in kidneys in long-term xenograft recipients...
  29. ncbi request reprint Clinical profile of four families with arrhythmogenic right ventricular cardiomyopathy caused by dominant desmoplakin mutations
    Barbara Bauce
    Division of Cardiology, University of Padua Medical School, Padova, Italy
    Eur Heart J 26:1666-75. 2005
    ....
  30. doi request reprint Intravascular macrophages in cardiac allograft biopsies for diagnosis of early and late antibody-mediated rejection
    Marny Fedrigo
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
    J Heart Lung Transplant 32:404-9. 2013
    ..The aim of our study was to evaluate the role of intravascular macrophages in the diagnosis of early and late antibody-mediated rejection (AMR) on endomyocardial biopsies (EMBs)...
  31. doi request reprint ABO-incompatible heart transplantation: crossing the immunological barrier
    Antonio Gambino
    Department of Cardiological, Thoracic and Vascular Science, Cardiac Surgery Unit, Italy
    J Cardiovasc Med (Hagerstown) 9:854-7. 2008
    ..Sharing the know-how about ABO-incompatible heart transplantation in newborns and infants awaiting transplantation will help in decreasing mortality among this group of patients...
  32. doi request reprint Multiple mutations in desmosomal proteins encoding genes in arrhythmogenic right ventricular cardiomyopathy/dysplasia
    Barbara Bauce
    Department of Cardiac Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy
    Heart Rhythm 7:22-9. 2010
    ..Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a progressive cardiomyopathy showing a wide clinical spectrum in terms of clinical expressions and prognoses...
  33. doi request reprint Quantitative assessment of endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy/dysplasia: an in vitro validation of diagnostic criteria
    Cristina Basso
    Pathological Anatomy, Department of Medico Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Eur Heart J 29:2760-71. 2008
    ..The Task Force criteria for the in vivo diagnosis of ARVC/D include tissue characterization by EMB as a major criterion...
  34. doi request reprint Comparison of clinical features of arrhythmogenic right ventricular cardiomyopathy in men versus women
    Barbara Bauce
    Department of Cardio Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy
    Am J Cardiol 102:1252-7. 2008
    ..The cause of the under-representation of women is not clear, even if potentially important factors such as sexual hormones and physical activity could play a role...
  35. doi request reprint Incidence, predictors, and outcome of conduction disorders after transcatheter self-expandable aortic valve implantation
    Chiara Fraccaro
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padova, Padua, Italy
    Am J Cardiol 107:747-54. 2011
    ..The independent predictors of PPM implantation were the depth of prosthesis implantation and pre-existing right bundle branch block...
  36. ncbi request reprint Hancock II bioprosthesis: a glance at the microscope in mid-long-term explants
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Italy
    J Thorac Cardiovasc Surg 126:99-105. 2003
    ..The aim of this investigation was to study the gross and microscopic features in Hancock II explants to assess the structural changes occurring with time...
  37. doi request reprint Relation of aortic valve weight to severity of aortic stenosis
    Renato Razzolini
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Padua, Italy
    Am J Cardiol 107:741-6. 2011
    ..0026). In conclusion, the heavier the valve, the less frequent were hypercholesterolemia, valve cholesterol clefts, hypertension, and diabetes mellitus...
  38. pmc The p.A897KfsX4 frameshift variation in desmocollin-2 is not a causative mutation in arrhythmogenic right ventricular cardiomyopathy
    Marzia De Bortoli
    Department of Biology, University of Padua, Padua, Italy
    Eur J Hum Genet 18:776-82. 2010
    ....
  39. doi request reprint Exercise-induced normalization of right precordial negative T waves in arrhythmogenic right ventricular cardiomyopathy
    Alessandro Zorzi
    Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy
    Am J Cardiol 112:411-5. 2013
    ..Exercise-induced NTWs changes are inaccurate in differentiating between ARVC patients and benign repolarization abnormalities...
  40. ncbi request reprint A prospective study of biopsy-proven myocarditis: prognostic relevance of clinical and aetiopathogenetic features at diagnosis
    Alida L P Caforio
    Division of Cardiology, Department of Cardiological, Thoracic, and Vascular Sciences, University of Padova Policlinico, Centro V Gallucci, Via Giustiniani 2, 35128 Padua, Italy
    Eur Heart J 28:1326-33. 2007
    ..We aimed at identifying aetiopathogenetic and prognostic markers in myocarditis, including viral genome on endomyocardial biopsy (EMB) by polymerase chain reaction (PCR) and serum anti-heart autoantibodies (AHA)...
  41. doi request reprint Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes
    Stefania Rizzo
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua 35121, Italy
    Cardiovasc Res 95:409-18. 2012
    ..We investigated whether mutation-induced intercalated disc remodelling impacts on electrophysiological properties before the onset of cell death and replacement fibrosis...
  42. doi request reprint The effects of basic fibroblast growth factor in an animal model of acute mechanically induced right ventricular hypertrophy
    Vladimiro L Vida
    Department of Paediatric and Congenital Cardiac Surgery Unit, University of Padua, Via Giustiniani 2, Padua, Italy
    Cardiol Young 22:436-42. 2012
    ..We analysed the functional adaptation and structural changes of the right ventricular myocardium, blood vessels, and interstitial tissue 30 days after the increased afterload...
  43. doi request reprint Bone-marrow-derived CXCR4-positive tissue-committed stem cell recruitment in human right ventricular remodeling
    Chiara Castellani
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Medical School, 35121 Padua, Italy
    Hum Pathol 41:1566-76. 2010
    ..The study provides evidences of the site-specific epicardial localization of stem cells in a model of pressure/volume overload and suggests that the epicardium acts as a permissive niche in normal and pathologic conditions...
  44. ncbi request reprint Host-derived circulating cells do not significantly contribute to cardiac regeneration in heterotopic rat heart transplants
    Simonetta Ausoni
    Department of Biomedical Sciences, University of Padua, Viale G Colombo 3, 35121 Padua, Italy
    Cardiovasc Res 68:394-404. 2005
    ....
  45. ncbi request reprint Overexpression of tumor necrosis factor (TNF)alpha and TNFalpha receptor I in human viral myocarditis: clinicopathologic correlations
    Fiorella Calabrese
    Department of Pathological Anatomy, University of Padua Medical School, Padua, Italy
    Mod Pathol 17:1108-18. 2004
    ..Cytokine effects are more strictly linked to overexpression of TNFRI...
  46. ncbi request reprint Long-term durability of the Hancock II porcine bioprosthesis
    Giulio Rizzoli
    Department of Cardiovascular Surgery, University of Padua Medical School, Italy
    J Thorac Cardiovasc Surg 126:66-74. 2003
    ....
  47. ncbi request reprint Effects of long-term administration of high-dose recombinant human antithrombin in immunosuppressed primate recipients of porcine xenografts
    Emanuele Cozzi
    Direzione Sanitaria, Padua General Hospital, Padua, Italy
    Transplantation 80:1501-10. 2005
    ..Fibrin deposition is central to the acute humoral rejection process occurring in the presence of consumptive coagulopathy when pig organs are transplanted into primates...
  48. ncbi request reprint Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies
    Cristina Basso
    Institute of Pathological Anatomy, University of Padua, Italy
    Eur Heart J 27:1847-54. 2006
    ..The recent discovery of gene mutations encoding intercalated disc proteins prompted us to perform a transmission electron microscopy study on endomyocardial biopsies...
  49. ncbi request reprint Three-dimensional electroanatomic voltage mapping increases accuracy of diagnosing arrhythmogenic right ventricular cardiomyopathy/dysplasia
    Domenico Corrado
    Division of Cardiology, University of Padua Medical School, Padua, Italy
    Circulation 111:3042-50. 2005
    ....
  50. doi request reprint Clinical implications of anti-heart autoantibodies in myocarditis and dilated cardiomyopathy
    Alida L P Caforio
    Division of Cardiology, Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
    Autoimmunity 41:35-45. 2008
    ....
  51. pmc Noninvasive cardiac screening in young athletes with ventricular arrhythmias
    Alexandros Klavdios Steriotis
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
    Am J Cardiol 111:557-62. 2013
    ..In conclusion, cardiac screening with noninvasive examinations remainsĀ a fundamental tool for the identification of a possible pathologic substrate and for the characterization of electrical instability...
  52. ncbi request reprint Sovering annuloplasty rings: experimental pathology in the sheep model
    Mila Della Barbera
    Institute of Pathological Anatomy, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 14:96-103. 2005
    ..The aim of the study was to test the biological compatibility of the new device in large animals in orthotopic position...
  53. doi request reprint Sudden cardiac death with normal heart: molecular autopsy
    Cristina Basso
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 19:321-5. 2010
    ....
  54. ncbi request reprint Recent developments on coronary microvasculopathy after heart transplantation: a new target in the therapy of cardiac allograft vasculopathy
    Francesco Tona
    Division of Cardiology, Department of Cardiological, Thoracic and Vascular Sciences, Centro V Gallucci University of Padova Policlinico, Padova, Italy
    Curr Vasc Pharmacol 10:206-15. 2012
    ..We review the role of coronary microvasculopathy in HTx, its prevention and new potential pharmacological interventions...
  55. ncbi request reprint Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy
    Kalliopi Pilichou
    Department of Biology, University of Padua Medical School, Padua, Italy
    Circulation 113:1171-9. 2006
    ..Therefore, desmoglein-2 (DSG2), the only desmoglein isoform expressed in cardiac myocytes, was screened in subjects with ARVC...
  56. doi request reprint Age is a risk factor for maladaptive changes of the pulmonary root in rats exposed to increased pressure loading
    Vladimiro L Vida
    Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 21:199-205. 2012
    ..The aim of this study was to evaluate, in an animal model, the histologic changes of the pulmonary root wall under increased pressure load...
  57. ncbi request reprint The pathology of TRI-Tech valve leaflet escape
    Mila Della Barbera
    Department of Medico Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    J Heart Valve Dis 21:241-6. 2012
    ..The study aim was to investigate leaflet escape in the TRI-Tech mechanical valve, as reported in three patients...
  58. doi request reprint Risk of sports: do we need a pre-participation screening for competitive and leisure athletes?
    Domenico Corrado
    Department of Cardiac, Thoracic and Vascular Science, University of Padua Medical School, Via Giustiniani, 2 35121 Padova, Italy
    Eur Heart J 32:934-44. 2011
    ..This review presents an appraisal of the available data and criticisms concerning screening programmes aimed to prevent SCD of either young competitive athletes or older individuals engaged in leisure-time sports activity...
  59. doi request reprint Pathological changes and myocardial remodelling related to the mode of shunting following surgical palliation for hypoplastic left heart syndrome
    Massimo A Padalino
    Pediatric and Congenital Cardiovascular Surgery Unit, University of Padua, Medical School, Padua, Italy
    Cardiol Young 18:415-22. 2008
    ....
  60. ncbi request reprint Arrhythmogenic right ventricular cardiomyopathy type 1 (ARVD1): confirmation of locus assignment and mutation screening of four candidate genes
    Alessandra Rampazzo
    Department of Biology, University of Padua, Italy
    Eur J Hum Genet 11:69-76. 2003
    ....
  61. ncbi request reprint Strategies for the prevention of sudden cardiac death during sports
    Domenico Corrado
    Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Via Giustiniani 2, Padua, Italy
    Eur J Cardiovasc Prev Rehabil 18:197-208. 2011
    ....
  62. ncbi request reprint Pre-participation screening of young competitive athletes for prevention of sudden cardiac death
    Domenico Corrado
    Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Pauda, Italy
    J Am Coll Cardiol 52:1981-9. 2008
    ..On the basis of current scientific evidence the implementation of a mass-screening program aimed to prevent athletic-field sudden cardiac death should be at least carefully considered by public health administrators worldwide...
  63. doi request reprint Prevalence of cardiomyopathy in Italian asymptomatic children with electrocardiographic T-wave inversion at preparticipation screening
    Federico Migliore
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy
    Circulation 125:529-38. 2012
    ..We prospectively assessed the prevalence, age relation, and underlying cardiomyopathy of T-wave inversion in children undergoing preparticipation screening...
  64. ncbi request reprint Regulatory mutations in transforming growth factor-beta3 gene cause arrhythmogenic right ventricular cardiomyopathy type 1
    Giorgia Beffagna
    Department of Biology, University of Padua, Via Ugo Bassi 58 B 35131 Padua, Italy
    Cardiovasc Res 65:366-73. 2005
    ..The objective of this study is to identify the gene involved in ARVD1, which has been elusive ever since its locus was mapped to chromosome 14q24.3...
  65. doi request reprint Imaging study of ventricular scar in arrhythmogenic right ventricular cardiomyopathy: comparison of 3D standard electroanatomical voltage mapping and contrast-enhanced cardiac magnetic resonance
    Martina Perazzolo Marra
    Departments of Cardiac, Thoracic, and Vascular Sciences, Radiology, and Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Circ Arrhythm Electrophysiol 5:91-100. 2012
    ..We compared endocardial voltage mapping (EVM) and contrast-enhanced cardiac magnetic resonance (CE-CMR) for imaging scar lesions in ARVC patients...
  66. ncbi request reprint Relevance of apoptosis in influencing recovery of hibernating myocardium
    Annalisa Angelini
    Department of Pathological Anatomy, University of Padua, Via Gabelli, 61, 35121 Padova, and Department of Non invasive Diagnostic Cardiology, San Raffaele Foundation Institute and University Hospital, Milan, Italy
    Eur J Heart Fail 9:377-83. 2007
    ..Myocyte necrosis is virtually absent in HM; however, cellular loss may take place by apoptosis, although this is controversial...
  67. ncbi request reprint Noninvasive risk stratification in arrhythmogenic right ventricular cardiomyopathy
    Pietro Turrini
    Department of Pathology, University of Padua Medical School, Padova, Italy
    Ann Noninvasive Electrocardiol 8:161-9. 2003
    ..At present only QRS dispersion, history of syncope and right and/or left ventricular abnormalities at radionuclide angiography proved to be independent noninvasive predictors of sudden death...
  68. ncbi request reprint Commissural dehiscence: a rare and peculiar cause of porcine valve structural deterioration
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy
    J Thorac Cardiovasc Surg 132:1017-22. 2006
    ..The aim of this study was to analyze the rate and mode of occurrence of this complication in first- and second-generation porcine bioprosthetic explants...
  69. ncbi request reprint Twenty years of progress and beckoning frontiers in cardiovascular pathology: cardiomyopathies
    Gaetano Thiene
    Institute of Pathological Anatomy, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 14:165-9. 2005
    ....
  70. ncbi request reprint Immune and nonimmune predictors of cardiac allograft vasculopathy onset and severity: multivariate risk factor analysis and role of immunosuppression
    Alida L P Caforio
    Department of Cardiology, University of Padua, Padua, Italy
    Am J Transplant 4:962-70. 2004
    ..7). High RS was an independent predictor for CAV onset, not severity/diffusion. This suggests an immune basis for CAV onset and nonimmune modulation for progression. High RS for severe grades may provide a predictor for patients at risk...
  71. pmc Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy
    Kalliopi Pilichou
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, 35121 Padua, Italy
    J Exp Med 206:1787-802. 2009
    ..Insight into mechanisms initiating myocardial damage in ARVC is a prerequisite to the future development of new therapies aimed at delaying onset or progression of the disease...
  72. ncbi request reprint Mid-term follow-up in patients with Biocor porcine bioprostheses
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy
    Cardiovasc Surg 10:238-44. 2002
    ..We reviewed survival and prosthetic complications of Biocor porcine bioprostheses implanted in mitral, aortic and mitro-aortic position...
  73. ncbi request reprint Myocarditis and dilated cardiomyopathy in athletes: diagnosis, management, and recommendations for sport activity
    Cristina Basso
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Via A Gabelli 61, 35121 Padova, Italy
    Cardiol Clin 25:423-9, vi. 2007
    ..This article focuses on uncommon heart diseases associated with an increased risk for sudden death during exercise, namely, myocarditis and dilated cardiomyopathy...
  74. ncbi request reprint Leaflet escape in a new bileaflet mechanical valve: TRI technologies
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Via A Gabelli, 61, 35121 Padova, Italy
    Circulation 107:2303-6. 2003
    ..This complication previously has been reported for both monoleaflet and bileaflet valve models. We report 2 leaflet escape occurrences observed in 2 patients who underwent valve replacement with a TRI Technologies valve prosthesis...
  75. doi request reprint von Willebrand factor abnormalities in aortic valve stenosis: Pathophysiology and impact on bleeding
    Alessandra Casonato
    Dept of Cardiologic, Thoracic and Vascular Sciences, Via Ospedale Civile 105, Padua, Italy
    Thromb Haemost 106:58-66. 2011
    ....
  76. ncbi request reprint Trends in sudden cardiovascular death in young competitive athletes after implementation of a preparticipation screening program
    Domenico Corrado
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Padua, Italy
    JAMA 296:1593-601. 2006
    ..A nationwide systematic preparticipation athletic screening was introduced in Italy in 1982. The impact of such a program on prevention of sudden cardiovascular death in the athlete remains to be determined...
  77. ncbi request reprint Infective endocarditis in bicuspid aortic valve: atrioventricular block as sign of perivalvular abscess
    Francesco Bacchion
    Institute of Pathology, University of Padua Medical School, Padua, Italy Department of Cardio Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy
    Cardiovasc Pathol 16:252-5. 2007
    ..Intravenous antibiotic therapy was undertaken, with rapid resolution of fever. He eventually underwent successful aortic homograft implantation and mitral valve repair with residual first-degree atrioventricular block...
  78. ncbi request reprint Calcified mass in the right atrium
    Vladimiro Vida
    Institute of Cardiac Surgery, University of Padua Medical School, Padua, Italy
    Ann Thorac Surg 79:717. 2005
  79. ncbi request reprint The bovine jugular vein conduit for right ventricular outflow tract reconstruction: a feasible alternative to homograft conduits?
    Tomaso Bottio
    Department of Cardiovascular Surgery, University of Padua Medical School, Italy
    J Thorac Cardiovasc Surg 127:1204-7. 2004
  80. ncbi request reprint Arrhythmogenic right ventricular cardiomyopathy causing sudden cardiac death in boxer dogs: a new animal model of human disease
    Cristina Basso
    Institute of Pathology, University of Padua Medical School, Padua, Italy
    Circulation 109:1180-5. 2004
    ..Efforts to discern relevant pathophysiological mechanisms have been impaired by lack of a suitable animal model...
  81. pmc Echocardiographic diagnosis of aortic valve papillary fibroelastoma
    Tomaso Bottio
    Institute of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy
    Tex Heart Inst J 31:322-3. 2004
  82. doi request reprint Anabolic androgenic steroids abuse and cardiac death in athletes: morphological and toxicological findings in four fatal cases
    Massimo Montisci
    Department of Environmental Medicine and Public Health, Section of Legal Medicine, University of Padua Medical School, Via G Falloppio 50, 35121 Padova, Italy
    Forensic Sci Int 217:e13-8. 2012
    ..Laboratory investigations should focus on AAS searching on a wide range of biological matrices to demonstrate type, magnitude and time of exposure...
  83. ncbi request reprint Guidelines for autopsy investigation of sudden cardiac death
    Cristina Basso
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
    Cesk Patol 46:43-8. 2010
    ....
  84. ncbi request reprint Age is a risk factor for maladaptive changes in rats exposed to increased pressure loading of the right ventricular myocardium
    Vladimiro L Vida
    Department of Pediatric Cardiac Surgery, University of Padua, Padua, Italy
    Cardiol Young 17:202-11. 2007
    ..To study the adaptive potential of the right ventricular myocardium after 30 days of mechanical-induced overload in rats from two different age groups...
  85. doi request reprint Viral detection and tumor necrosis factor alpha profile in tracheal aspirates from children with suspicion of myocarditis
    Elisa Carturan
    Department of Medical Diagnostic Science and Special Therapies, Padua, Italy
    Diagn Mol Pathol 17:21-7. 2008
    ..09 vs. 55.61+/-20.36, P=0.04). TA seems to be an excellent tool for viral investigation in pediatric patients with suspicion of myocarditis. The analysis of TNFalpha in TA may represent an important marker to better define patient status...
  86. ncbi request reprint Methotrexate for immunosuppression in life-supporting pig-to-cynomolgus monkey renal xenotransplantation
    Emanuele Cozzi
    Direzione Sanitaria, Padua General Hospital, Padua, Italy
    Xenotransplantation 10:587-95. 2003
    ..We conclude that MTX is scarcely effective as an immunosuppressant, be it for induction or maintenance, in pig-to-cynomolgus monkey renal xenotransplantation...
  87. doi request reprint Myocardial edema underlies dynamic T-wave inversion (Wellens' ECG pattern) in patients with reversible left ventricular dysfunction
    Federico Migliore
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Padova, Italy
    Heart Rhythm 8:1629-34. 2011
    ..The pathophysiologic basis of this ECG pattern remains to be elucidated...
  88. doi request reprint Molecular biology and clinical management of arrhythmogenic right ventricular cardiomyopathy/dysplasia
    Domenico Corrado
    Inherited Arrhythmogenic Cardiomyopathy Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy
    Heart 97:530-9. 2011
    ....
  89. doi request reprint Octanediol treatment of glutaraldehyde fixed bovine pericardium: evidence of anticalcification efficacy in the subcutaneous rat model
    Elena Pettenazzo
    Department of Medical Diagnostic Sciences, University of Padua Medical School, Via A Gabelli 61, Padua, Italy
    Eur J Cardiothorac Surg 34:418-22. 2008
    ..Octanediol treatment is an ethanolic solution (40%) containing a long chain aliphatic alcohol (5% 1,2-octanediol) that removes lipids without diminishing the stability of collagen...
  90. ncbi request reprint Abnormal total ejection isovolume index as early noninvasive marker of chronic rejection in heart transplantation
    Francesco Tona
    Division of Cardiology, Department of Clinical and Experimental Medicine, University of Padua Medical School, Policlinico Universitario, Via N Giustiniani 2, 35128 Padua, Italy
    Transpl Int 18:303-8. 2005
    ..Extended prospective studies are warranted to clarify its potential role as a negative prognostic marker in HT...
  91. ncbi request reprint Images in cardiovascular medicine. Left ventricular mass after treatment with chemotherapic drugs
    Vladimiro Vida
    Institute of Paediatric Cardiac Surgery, University of Padua Medical School, Padova, Italy
    Circulation 109:e300-1. 2004
  92. ncbi request reprint Antiphospholipid syndrome and right atrial mass
    Cristina Basso
    Institute of Pathological Anatomy, University of Padua Medical School, Padua, Italy
    J Thorac Cardiovasc Surg 130:1462-3. 2005
  93. doi request reprint Prophylactic implantable defibrillator in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and no prior ventricular fibrillation or sustained ventricular tachycardia
    Domenico Corrado
    Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Via Giustiniani 2, Padua, Italy
    Circulation 122:1144-52. 2010
    ..The role of implantable cardioverter-defibrillator (ICD) in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and no prior ventricular fibrillation (VF) or sustained ventricular tachycardia is an unsolved issue...
  94. ncbi request reprint Arrhythmogenic right ventricular cardiomyopathy in athletes: diagnosis, management, and recommendations for sport activity
    Cristina Basso
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Medical School, Via A Gabelli 61, 35121 Padova, Italy
    Cardiol Clin 25:415-22, vi. 2007
    ..Systematic cardiovascular screening (including 12-lead ECG) of all subjects embarking on sports activity has the potential to identify those athletes at risk and to reduce mortality...
  95. ncbi request reprint Coronary thrombosis and sudden death after an enteroviral infection. Case report
    Fiorella Calabrese
    Department of Pathology, University of Padua Medical School, Padua, Italy
    APMIS 111:315-8. 2003
    ..Enteroviral infection may play an important role in coronary plaque instability and may precipitate thrombotic occlusion...
  96. ncbi request reprint How to screen athletes for cardiovascular diseases
    Domenico Corrado
    Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova Medical School, Via Giustiniani 2, 35121 Padova, Italy
    Cardiol Clin 25:391-7, v-vi. 2007
    ....
  97. ncbi request reprint Atrial septal mass: transesophageal echocardiographic assessment
    Giulio Rizzoli
    Institute of Cardiovascular Surgery, University of Padua Medical School, 35121 Padua, Italy
    J Thorac Cardiovasc Surg 128:767-9. 2004
  98. ncbi request reprint Myocardial bridging, a frequent component of the hypertrophic cardiomyopathy phenotype, lacks systematic association with sudden cardiac death
    Cristina Basso
    Department of Medico Diagnostic Sciences, Pathological Anatomy, University of Padua Medical School, Padova, Italy
    Eur Heart J 30:1627-34. 2009
    ..The clinical significance attributable to myocardial bridging of left anterior descending coronary artery in hypertrophic cardiomyopathy (HCM) remains controversial...
  99. ncbi request reprint Screening for ryanodine receptor type 2 mutations in families with effort-induced polymorphic ventricular arrhythmias and sudden death: early diagnosis of asymptomatic carriers
    Barbara Bauce
    Department of Cardiology, University of Padua Medical School, Via A Gabelli, 86 35121 Padua, Italy
    J Am Coll Cardiol 40:341-9. 2002
    ..We sought to establish the role of genetic screening for ryanodine receptor type 2 (RyR2) gene mutations in families with effort-induced polymorphic ventricular arrhythmia (PVA), syncope and juvenile sudden death...
  100. ncbi request reprint Is it time to include ion channel diseases among cardiomyopathies?
    Domenico Corrado
    Department of Cardiology, University of Padua Medical School, Padova, Italy
    J Electrocardiol 38:81-7. 2005
    ....
  101. ncbi request reprint Toward a cardiovascular pathology training report on the forum held in Vancouver, March 6, 2004, Society for Cardiovascular Pathology
    Gaetano Thiene
    Cardiovascular Pathology, University of Padua Medical School, Padova, Italy
    Cardiovasc Pathol 14:312-9. 2005
    ..This article reports the outcome of the forum and directions that may lead to a vibrant future for well-trained cardiovascular pathologists...