D Taramelli

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Synergistic and antagonistic interactions between haemozoin and bacterial endotoxin on human and mouse macrophages
    N Basilico
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Parassitologia 45:135-40. 2003
  2. pmc Anti-plasmodial and insecticidal activities of the essential oils of aromatic plants growing in the Mediterranean area
    Mario dell'Agli
    Dipartimento di Scienze Farmacologiche e Biomolecolari, Universita degli Studi di Milano, Milan, Italy
    Malar J 11:219. 2012
  3. pmc The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria
    Patrice N Mimche
    Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Malar J 10:S10. 2011
  4. pmc CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives
    Ian C Boulton
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Malar J 9:202. 2010
  5. pmc Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria
    Mario dell'Agli
    Dipartimento di Scienze Farmacologiche, Universita degli Studi di Milano, Via Balzaretti, 9 20133 Milano, Italy
    Malar J 9:208. 2010
  6. ncbi request reprint The effect of synthetic malaria pigment (beta-haematin) on adhesion molecule expression and interleukin-6 production by human endothelial cells
    D Taramelli
    Institute of Medical Microbiology, University of Milan, Italy
    Trans R Soc Trop Med Hyg 92:57-62. 1998
  7. ncbi request reprint Ultrastructural characteristics, biological activity and pharmacological relevance of synthetic malaria pigment (beta-haematin)
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Via Pascal 36, 20133 Milano, Italy
    Parassitologia 43:45-9. 2001
  8. pmc Inhibition of intramacrophage growth of Penicillium marneffei by 4-aminoquinolines
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Antimicrob Agents Chemother 45:1450-5. 2001
  9. ncbi request reprint A fine balance between oxidised and reduced haem controls the survival of intraerythrocytic plasmodia
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Italy
    Parassitologia 41:205-8. 1999
  10. ncbi request reprint Macrophage preconditioning with synthetic malaria pigment reduces cytokine production via heme iron-dependent oxidative stress
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Lab Invest 80:1781-8. 2000

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Synergistic and antagonistic interactions between haemozoin and bacterial endotoxin on human and mouse macrophages
    N Basilico
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Parassitologia 45:135-40. 2003
    ..These data rise the question of whether and how in vivo concomitant gram(-) bacteremia may affect the pathogenesis and/or the immune response of malaria infections and vice versa...
  2. pmc Anti-plasmodial and insecticidal activities of the essential oils of aromatic plants growing in the Mediterranean area
    Mario dell'Agli
    Dipartimento di Scienze Farmacologiche e Biomolecolari, Universita degli Studi di Milano, Milan, Italy
    Malar J 11:219. 2012
    ....
  3. pmc The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria
    Patrice N Mimche
    Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Malar J 10:S10. 2011
    ..This review discusses the properties of the plant immune-modifier curcumin and its potential as an adjunctive therapy for the management of this complication...
  4. pmc CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives
    Ian C Boulton
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Malar J 9:202. 2010
    ..It is hoped that the recommendations will help to guide the priorities of the European anti-malarial research as well as the wider global discovery agenda in the coming decade...
  5. pmc Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria
    Mario dell'Agli
    Dipartimento di Scienze Farmacologiche, Universita degli Studi di Milano, Via Balzaretti, 9 20133 Milano, Italy
    Malar J 9:208. 2010
    ..The aim of the present study was to explore whether the anti-malarial effect of OMARIA could also be sustained via other mechanisms among those associated to the host immune response...
  6. ncbi request reprint The effect of synthetic malaria pigment (beta-haematin) on adhesion molecule expression and interleukin-6 production by human endothelial cells
    D Taramelli
    Institute of Medical Microbiology, University of Milan, Italy
    Trans R Soc Trop Med Hyg 92:57-62. 1998
    ....
  7. ncbi request reprint Ultrastructural characteristics, biological activity and pharmacological relevance of synthetic malaria pigment (beta-haematin)
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Via Pascal 36, 20133 Milano, Italy
    Parassitologia 43:45-9. 2001
    ..This was confirmed by the observation that thiol-reducing agents (NAC, cystein) were able to inhibit BH formation and were toxic to parasites in vitro...
  8. pmc Inhibition of intramacrophage growth of Penicillium marneffei by 4-aminoquinolines
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Antimicrob Agents Chemother 45:1450-5. 2001
    ..marneffei growth. These results suggest that CQ has a potential for use in prophylaxis of P. marneffei infections in human immunodeficiency virus-infected patients in countries where P. marneffei is endemic...
  9. ncbi request reprint A fine balance between oxidised and reduced haem controls the survival of intraerythrocytic plasmodia
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Italy
    Parassitologia 41:205-8. 1999
    ..It is also the target of in-use antimalarial drugs and newer compounds. This reaction and the inhibition thereof can be reproduced and studied in vitro...
  10. ncbi request reprint Macrophage preconditioning with synthetic malaria pigment reduces cytokine production via heme iron-dependent oxidative stress
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Lab Invest 80:1781-8. 2000
    ....
  11. pmc Effects of iron on extracellular and intracellular growth of Penicillium marneffei
    D Taramelli
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Infect Immun 68:1724-6. 2000
    ..Likewise, exogenous iron enhances and iron chelators inhibit the extracellular growth of P. marneffei. These results suggest that iron availability critically affects immunity to and the pathogenicity of P. marneffei...
  12. ncbi request reprint Prooxidant activity of beta-hematin (synthetic malaria pigment) in arachidonic acid micelles and phospholipid large unilamellar vesicles
    F Omodeo-Sale
    Institute of General Physiology and Biochemistry, University of Milan, Via Trentacoste 2, I 20134, Milan, Italy
    Biochem Pharmacol 61:999-1009. 2001
    ..7) and chloroquine. UV/Vis spectroscopy of AH aggregates at acidic pH, low GSH concentrations and chloroquine suggests a shift of AH aggregates toward the less aggregated state, more active as peroxidation catalyst...
  13. doi request reprint Hypoxia modulates the effect of dihydroartemisinin on endothelial cells
    S D'Alessandro
    Dipartimento di Sanità Pubblica Microbiologia Virologia, Universita di Milano, Via Pascal 36, Milan, Italy
    Biochem Pharmacol 82:476-84. 2011
    ..This should be considered when studying both the effects of artemisinin derivatives as antimalarials and the potential therapeutic applications of these drugs as anti-tumor agents...
  14. ncbi request reprint Macrophage populations of different origins have distinct susceptibilities to lipid peroxidation induced by beta-haematin (malaria pigment)
    F Omodeo-Sale
    Istituto di Fisiologia Generale e Chimica Biologica, Universita di Milano, Milan, Italy
    FEBS Lett 433:215-8. 1998
    ..These findings offer a new interpretation for the contentious immunomodulatory effects of beta-haematin reported for phagocytes of different origins...
  15. ncbi request reprint Plasmodium falciparum parasitized red blood cells modulate the production of endothelin-1 by human endothelial cells
    N Basilico
    Institute of Microbiology and School of Pharmacy, University of Milan, Milan, Italy
    Minerva Med 95:153-8. 2004
    ..falciparum pRBC under normoxic or hypoxic conditions...
  16. ncbi request reprint Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network
    N Basilico
    Dipartimento Salute Pubblica Microbiologia Virologia, Universita di Milano, Italy
    Parassitologia 50:133-6. 2008
    ....
  17. ncbi request reprint Oxidative stress and rheology in severe malaria
    A M Dondorp
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Redox Rep 8:292-4. 2003
    ..Since this seems to be caused by oxidative damage to the red blood cell membrane, the anti-oxidant N-acetylcysteine is a promising candidate for adjunctive treatment in severe malaria, which still has a mortality rate as high as 20%...