Claudia Stefanutti

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi request reprint Lipoprotein apheresis in the management of familial hypercholesterolaemia: historical perspective and recent advances
    Claudia Stefanutti
    Extracorporeal Therapeutic Techniques Unit, Lipid Clinic and Atherosclerosis Prevention Centre, Immunohematology and Transfusion Medicine, Umberto I Hospital, Rome, Italy
    Curr Atheroscler Rep 17:465. 2015
  2. ncbi request reprint Hypertriglyceridaemia, postprandial lipaemia and non-HDL cholesterol
    Claudia Stefanutti
    Extracorporeal Therapeutic Techniques Lipid Clinic and Atherosclerosis Prevention Centre Immunohematology and Transfusion Medicine Department of Molecular Medicine, University of Rome Sapienza Umberto I Hospital 155, Viale del Policlinico, Rome, 00161, Italy EU
    Curr Pharm Des 20:6238-48. 2014
  3. ncbi request reprint Misfolding of apoprotein B-100, LDL aggregation and 17-β -estradiol in atherogenesis
    R Brunelli
    Unità di Tecniche Terapeutiche Extracorporee Centro per lo Studio, Diagnosi, Terapia delle Dislipidemie e Prevenzione della Aterosclerosi Immunoematologia e Medicina Trasfusionale Dipartimento di Medicina Molecolare Università di Roma Sapienza, Roma, Italy
    Curr Med Chem 21:2276-83. 2014
  4. ncbi request reprint Severe hypertriglyceridemia-related acute pancreatitis
    Claudia Stefanutti
    Department of Immunohematology and Transfusion Medicine, Extracorporeal Therapeutic Techniques Unit, Rome, Italy
    Ther Apher Dial 17:130-7. 2013
  5. ncbi request reprint Lipoprotein apheresis: state of the art and novelties
    C Stefanutti
    Extracorporeal Therapeutic Techniques Unit Immunohematology and Transfusion Medicine, Department of Molecular Medicine, University of Rome Sapienza, Umberto I Hospital, 155 Viale del Policlinico, I 00161 Rome, Italy
    Atheroscler Suppl 14:19-27. 2013
  6. ncbi request reprint A three month-old infant with severe hyperchylomicronemia: molecular diagnosis and extracorporeal treatment
    Claudia Stefanutti
    Extracorporeal Therapeutic Unit, Immunohematology and Transfusion Medicine, Department of Molecular Medicine, University of Rome Sapienza, Umberto I Hospital, 155, Viale del Policlinico, I 00161 Rome, Italy
    Atheroscler Suppl 14:73-6. 2013
  7. ncbi request reprint Multiple lipid-lowering treatment in pediatric patients with hyperlipidemia
    Claudia Stefanutti
    Lipid Clinic and Atherosclerosis Prevention Centre, Department of Molecular Medicine and Department of Immunohematology and Transfusion Medicine, University of Rome La Sapienza, Rome I EU, Italy
    Med Chem 8:1171-81. 2012
  8. ncbi request reprint Therapeutic plasma exchange in patients with severe hypertriglyceridemia: a multicenter study
    Claudia Stefanutti
    University of Rome La Sapienza, Umberto I Hospital, Department of Clinical and Medical Therapy, Plasmapheresis Unit, Rome, Italy
    Artif Organs 33:1096-102. 2009
  9. ncbi request reprint Immunoadsorption apheresis and immunosuppressive drug therapy in the treatment of complicated HCV-related cryoglobulinemia
    Claudia Stefanutti
    Department of Clinical and Medical Therapy, Plasmapheresis Unit, University of Rome La Sapienza, Policlinico Umberto I Rome, Rome, Italy
    J Clin Apher 24:241-6. 2009
  10. ncbi request reprint Effects of low-dose atorvastatin and rosuvastatin on plasma lipid profiles: a long-term, randomized, open-label study in patients with primary hypercholesterolemia
    Fabio Mazza
    Department of Clinical and Medical Therapy, University of Rome La Sapienza, Umberto I Hospital, Rome, Italy
    Am J Cardiovasc Drugs 8:265-70. 2008

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Lipoprotein apheresis in the management of familial hypercholesterolaemia: historical perspective and recent advances
    Claudia Stefanutti
    Extracorporeal Therapeutic Techniques Unit, Lipid Clinic and Atherosclerosis Prevention Centre, Immunohematology and Transfusion Medicine, Umberto I Hospital, Rome, Italy
    Curr Atheroscler Rep 17:465. 2015
    ..Depending on the outcome of current trials, it seems likely that these compounds, used alone or combined with lipoprotein apheresis, will markedly improve the management of refractory FH. ..
  2. ncbi request reprint Hypertriglyceridaemia, postprandial lipaemia and non-HDL cholesterol
    Claudia Stefanutti
    Extracorporeal Therapeutic Techniques Lipid Clinic and Atherosclerosis Prevention Centre Immunohematology and Transfusion Medicine Department of Molecular Medicine, University of Rome Sapienza Umberto I Hospital 155, Viale del Policlinico, Rome, 00161, Italy EU
    Curr Pharm Des 20:6238-48. 2014
    ..This review focuses on TG, PPL, postprandial hyperlipidaemia and non-HDL-C, their relationships and potential predictive role in atherogenesis and CVD. ..
  3. ncbi request reprint Misfolding of apoprotein B-100, LDL aggregation and 17-β -estradiol in atherogenesis
    R Brunelli
    Unità di Tecniche Terapeutiche Extracorporee Centro per lo Studio, Diagnosi, Terapia delle Dislipidemie e Prevenzione della Aterosclerosi Immunoematologia e Medicina Trasfusionale Dipartimento di Medicina Molecolare Università di Roma Sapienza, Roma, Italy
    Curr Med Chem 21:2276-83. 2014
    ..Potential implications for the development of novel therapeutic approaches might be hypothesized in perspective. The existing evidence is discussed and reported in this review. ..
  4. ncbi request reprint Severe hypertriglyceridemia-related acute pancreatitis
    Claudia Stefanutti
    Department of Immunohematology and Transfusion Medicine, Extracorporeal Therapeutic Techniques Unit, Rome, Italy
    Ther Apher Dial 17:130-7. 2013
    ..The current evidence on management of acute pancreatitis and severe hypertriglyceridemia, focusing on symptoms, treatment and potential complications is reviewed herein...
  5. ncbi request reprint Lipoprotein apheresis: state of the art and novelties
    C Stefanutti
    Extracorporeal Therapeutic Techniques Unit Immunohematology and Transfusion Medicine, Department of Molecular Medicine, University of Rome Sapienza, Umberto I Hospital, 155 Viale del Policlinico, I 00161 Rome, Italy
    Atheroscler Suppl 14:19-27. 2013
    ..It is expected that these potent new agents will be combined with LA in the treatment of the most severe forms of hyperlipidemia...
  6. ncbi request reprint A three month-old infant with severe hyperchylomicronemia: molecular diagnosis and extracorporeal treatment
    Claudia Stefanutti
    Extracorporeal Therapeutic Unit, Immunohematology and Transfusion Medicine, Department of Molecular Medicine, University of Rome Sapienza, Umberto I Hospital, 155, Viale del Policlinico, I 00161 Rome, Italy
    Atheroscler Suppl 14:73-6. 2013
    ..It often requires urgent and suitable treatment to avoid acute pancreatitis. The aim of this study was the molecular characterization and treatment of a 3 month-old infant with plasma triglycerides (TG) > 300 mmol/L...
  7. ncbi request reprint Multiple lipid-lowering treatment in pediatric patients with hyperlipidemia
    Claudia Stefanutti
    Lipid Clinic and Atherosclerosis Prevention Centre, Department of Molecular Medicine and Department of Immunohematology and Transfusion Medicine, University of Rome La Sapienza, Rome I EU, Italy
    Med Chem 8:1171-81. 2012
    ..4 ± 10 years; males 35, females 11). The follow-up visits were at 3, 6 and 9 months, respectively. The time period considered was of 9 months. The results obtained in the four groups after 9 months of treatment are given below:..
  8. ncbi request reprint Therapeutic plasma exchange in patients with severe hypertriglyceridemia: a multicenter study
    Claudia Stefanutti
    University of Rome La Sapienza, Umberto I Hospital, Department of Clinical and Medical Therapy, Plasmapheresis Unit, Rome, Italy
    Artif Organs 33:1096-102. 2009
    ....
  9. ncbi request reprint Immunoadsorption apheresis and immunosuppressive drug therapy in the treatment of complicated HCV-related cryoglobulinemia
    Claudia Stefanutti
    Department of Clinical and Medical Therapy, Plasmapheresis Unit, University of Rome La Sapienza, Policlinico Umberto I Rome, Rome, Italy
    J Clin Apher 24:241-6. 2009
    ..001), and CSA versus CSB (P = 0.03), respectively. The changes observed were favorable to the patients assigned to the IA plus IDT group (A): in most case relief of symptoms and complications have been obtained...
  10. ncbi request reprint Effects of low-dose atorvastatin and rosuvastatin on plasma lipid profiles: a long-term, randomized, open-label study in patients with primary hypercholesterolemia
    Fabio Mazza
    Department of Clinical and Medical Therapy, University of Rome La Sapienza, Umberto I Hospital, Rome, Italy
    Am J Cardiovasc Drugs 8:265-70. 2008
    ....
  11. ncbi request reprint Combined treatment with Dif1stat and diet reduce plasma lipid indicators of moderate hypercholesterolemia more effectively than diet alone: a randomized trial in parallel groups
    Claudia Stefanutti
    Clinical and Medical Therapy Department, Umberto I Hospital Rome I EU, University of Rome La Sapienza, Rome, Italy
    Lipids 44:1141-8. 2009
    ..001). Dif1stat, given with a suitable diet, was well tolerated in the long-term and induced an anti-atherogenic plasma lipid and lipoprotein profile, in patients with moderate hypercholesterolemia...
  12. ncbi request reprint [LDL apheresis: an update and overview. LDL apheresis in Sardinia, Italy (SMILDLa)]
    Claudia Stefanutti
    Dipartimento di Medicina Molecolare, Universita di Roma, Policlinico, Roma, Italy
    G Ital Nefrol 29:S14-8. 2012
    ..Finally, data acquired by the Italian Multicenter Study on LDLa Working Group were highlighted and the new evidence in the literature discussed...
  13. ncbi request reprint Aorta and coronary angiographic follow-up of children with severe hypercholesterolemia treated with low-density lipoprotein apheresis
    Claudia Stefanutti
    Plasmapheresis Unit, Clinical and Medical Therapy Department, Umberto I Hospital, University of Rome La Sapienza, Rome I EU, Italy
    Transfusion 49:1461-70. 2009
    ..In this single-center, nonrandomized, prospective study, 11 children with severe genetic hypercholesterolemia, without previous cardiovascular disease events, were treated with low-density lipoprotein apheresis (LDLa)...
  14. ncbi request reprint Italian multicenter study on low-density lipoprotein apheresis Working Group 2009 survey
    Claudia Stefanutti
    Department of Immunohematology and Transfusion Medicine, Extracorporeal Therapeutic Techniques Unit, University of Rome La Sapienza, Rome, Italy
    Ther Apher Dial 17:169-78. 2013
    ..sessions: 36; average plasma volume treated: 3000 mL) for sudden hearing loss (SHL). Relief of symptoms was obtained, independently of the system used (HELP; cascade-filtration)...
  15. ncbi request reprint Italian Multicenter Study on Low-Density Lipoprotein Apheresis: retrospective analysis (2007)
    Claudia Stefanutti
    Plasmapheresis Unit, Department of Clinical and Medical Therapy, University of Rome La Sapienza, Umberto I Hospital, Rome, Italy
    Ther Apher Dial 14:79-86. 2010
    ....
  16. ncbi request reprint LDL apheresis: a novel technique (LIPOCOLLECT 200)
    Claudia Stefanutti
    Department of Clinical and Medical Therapy, Plasmapheresis Unit, University of Rome La Sapienza, Policlinico Umberto I, Rome, Italy
    Artif Organs 33:1103-8. 2009
    ..Clinically, all sessions were well tolerated and undesired reactions were not reported. The Lipocollect 200 adsorber proved to have a good biocompatibility. In this study, the adsorber reusability for several sessions was confirmed...
  17. ncbi request reprint Lipid and low-density-lipoprotein apheresis. Effects on plasma inflammatory profile and on cytokine pattern in patients with severe dyslipidemia
    Claudia Stefanutti
    Extracorporeal Therapeutic Techniques Unit Immunohematology and Transfusion Medicine, Department of Molecular Medicine, La Sapienza University of Rome, Italy
    Cytokine 56:842-9. 2011
    ....
  18. ncbi request reprint Apheresis-inducible cytokine pattern change in severe, genetic dyslipidemias
    Claudia Stefanutti
    Extracorporeal Therapeutic Techniques Unit Immunohematology and Transfusion Medicine, Department of Molecular Medicine, University of Rome La Sapienza, Umberto I Hospital, Rome, Italy
    Cytokine 56:835-41. 2011
    ....
  19. ncbi request reprint Cyclophosphamide and immunoadsorption apheresis treatment of lupus nephritis nonresponsive to drug therapy alone
    Claudia Stefanutti
    Applied Clinical and Medical Therapy Department, University of Rome La Sapienza, Policlinico Umberto I, Rome, Italy
    BioDrugs 19:129-33. 2005
    ..After twelve sessions of IA over 3 months, renal function was completely restored and the patient discharged. Although it is not proven, the concomitant use of cyclophosphamide could presumably improve the final clinical outcome...