Research Topics
Species | V StanghelliniSummaryAffiliation: University of Bologna Country: Italy Publications
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Publications
New developments in the treatment of functional dyspepsiaVincenzo Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Drugs 63:869-92. 2003..e., P2X2/3 receptors), NMDA receptors (NR2B subtype), protease-activated receptor-2, the vanilloid receptor-1, tachykinin receptors (NK(1)/NK(2)) and cholecystokinin (CCK)(1) receptors...- Interactions between commensal bacteria and gut sensorimotor function in health and diseaseGiovanni Barbara
Department of Internal Medicine and Gastroenterology, Univeristy of Bologna, Bologna, Italy
Am J Gastroenterol 100:2560-8. 2005..The potential benefit of antibiotic and probiotic therapy is currently under investigation and opens new perspectives in irritable bowel syndrome treatment... 
Chronic intestinal pseudo-obstructionAlexandra Antonucci
Department of Internal Medicine and Gastroenterology, St Orsola Malpighi Hospital, Via Massarenti 9, Bologna I 40138, Italy
World J Gastroenterol 14:2953-61. 2008..Treatment of intestinal pseudo-obstruction involves nutritional, pharmacological and surgical therapies, but it is often unsatisfactory and the long-term outcome is generally poor in the majority of cases...- Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via FasRoberto De Giorgio
Department of Internal Medicine and Gastroenterology, Centro Unificato di Ricerca BioMedica Applicata, University of Bologna, Bologna, Italy
Gastroenterology 135:601-9. 2008..In this study we tested the hypothesis that sera from a subpopulation of patients with CIP contain autoantibodies that activate autophagy via a Fas-dependent pathway in cultured human neuroblastoma SH-Sy5Y cells... - Three-month prevalence rates of gastrointestinal symptoms and the influence of demographic factors: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST)V Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Scand J Gastroenterol Suppl 231:20-8. 1999.... - Systematic review: do we need a new gastro-oesophageal reflux disease questionnaire?V Stanghellini
S Orsola Malpighi Hospital, Bologna, Italy
Digestion 75:3-16. 2007..Self-assessed symptom questionnaires are now key instruments in clinical trials... - Predictors of gastroparesis in out-patients with secondary and idiopathic upper gastrointestinal symptomsV Stanghellini
Department of Internal Medicine, University of Bologna, St Orsola Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy
Dig Liver Dis 35:389-96. 2003..Delayed gastric emptying occurs frequently in patients with upper gastrointestinal symptoms associated with functional or organic diseases... - Unsolved problems in the management of patients with gastro-oesophageal reflux diseaseV Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Policlinico S Orsola Malpighi, Via Massarenti, 9 Bologna 1 40138, Italy
Dig Liver Dis 35:843-8. 2003..The high prevalence of gastro-oesophageal reflux disease in the general population and the relatively high management costs should prompt any doctor to seek the best possible therapeutic approach... - Review article: Helicobacter pylori, mucosal inflammation and symptom perception--new insights into an old hypothesisV Stanghellini
Department of Internal Medicine and Gastroenterology, St Orsola Hospital, University of Bologna, Via Massarenti 9, I 40138 Bologna, Italy
Aliment Pharmacol Ther 15:28-32. 2001..The identification of these mechanisms may provide a better understanding of the pathophysiology of H. pylori-related dyspepsia and prompt innovative therapeutic approaches... - Systematic review: do we need a new gastro-oesophageal reflux disease questionnaire?V Stanghellini
S Orsola Malpighi Hospital, Bologna, Italy
Aliment Pharmacol Ther 19:463-79. 2004..Self-assessed symptom questionnaires are now key instruments in clinical trials... - Review Article: pain versus discomfort--is differentiation clinically useful?V Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Aliment Pharmacol Ther 15:145-9. 2001..It is likely that precise symptom definitions and history-taking will be of pivotal importance in management strategies for functional dyspepsia... - Standards for non-invasive methods for gastrointestinal motility: scintigraphy. A position statement from the Gruppo Italiano di Studio Motilità Apparato Digerente (GISMAD)V Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Dig Liver Dis 32:447-52. 2000.... - ReQuest-- the challenge of quantifying both esophageal and extra-esophageal manifestations of GERDVincenzo Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy
Best Pract Res Clin Gastroenterol 18:27-30. 2004.... - Relationship between upper gastrointestinal symptoms and lifestyle, psychosocial factors and comorbidity in the general population: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST)V Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Scand J Gastroenterol Suppl 231:29-37. 1999.... - Dyspepsia and dyspepsia subgroups. Not all roads lead to RomeV Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna S Orsola-Malpighi Hospital, Italy
Dig Liver Dis 34:316-8. 2002 
Natural history of intestinal failure induced by chronic idiopathic intestinal pseudo-obstructionV Stanghellini
Department of Clinical Medicine, University of Bologna, Bologna, Italy
Transplant Proc 42:15-8. 2010..A substantial percentage of patients requires parenteral nutrition. Failure of this nutritional support represents an indication for small bowel transplantation...- Patient-reported outcomes and gut dysmotility in functional gastrointestinal disordersR F Cogliandro
Department of Clinical Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
Neurogastroenterol Motil 23:1084-91. 2011..The present study compared clinical features, small bowel motility, and quality of life (QoL) in patients with CIIP or severe functional gastrointestinal disorders (SFGID), compared to irritable bowel syndrome (IBS)... - Chronic intestinal pseudo-obstruction: manifestations, natural history and managementV Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Neurogastroenterol Motil 19:440-52. 2007..This article focuses on the main clinical features, the management and long-term outcome of patients affected by CIPO, with particular emphasis on those aspects which remain a matter of debate... - Effect of mesalazine on mucosal immune biomarkers in irritable bowel syndrome: a randomized controlled proof-of-concept studyR Corinaldesi
Department of Clinical Medicine and Center for Applied Biomedical Research, University of Bologna, Bologna, Italy
Aliment Pharmacol Ther 30:245-52. 2009..Intestinal immune infiltration contributes to symptoms in patients with irritable bowel syndrome (IBS)... - Role of antibiotic therapy on long-term germ excretion in faeces and digestive symptoms after Salmonella infectionG Barbara
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Aliment Pharmacol Ther 14:1127-31. 2000..Acute Salmonella gastroenteritis induces long-lasting digestive symptoms in up to one-third of subjects. The role of antimicrobial therapy on persistent post-infectious symptoms is unknown... - Diagnosis and therapy of irritable bowel syndromeR De Giorgio
Departments of Internal Medicine and Gastroenterology and Pharmacology, University of Bologna, Italy
Aliment Pharmacol Ther 20:10-22. 2004..A wide array of potentially useful drugs are currently under consideration in pre-clinical trials. A better understanding of the pathogenetic mechanisms underlying IBS may help to develop more effective drugs for this disease... - New insights into human enteric neuropathiesR De Giorgio
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Neurogastroenterol Motil 16:143-7. 2004..The study of the ENS abnormalities in gut dysmotility provides a framework to better understand the mechanisms involved in degeneration and neuronal loss and fosters the development of targeted therapeutic options... - Use of macrogol 4000 in chronic constipationR De Giorgio
Department of Clinical Medicine, School of Medicine, Alma Mater Studiorum University, Bologna, Italy
Eur Rev Med Pharmacol Sci 15:960-6. 2011..Lifestyle changes do not usually meet with complete patient satisfaction. Other treatments include different types of laxatives. Of these, osmotic laxatives appear one of the most effective and are, therefore, frequently prescribed... - Gastro-oesophageal reflux and interstitial lung diseaseB Salvioli
Department of Internal Medicine and Gastroenterology, S Orsola Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
Dig Liver Dis 38:879-84. 2006..Gastro-oesophageal reflux appears to be more prevalent in idiopathic pulmonary fibrosis than in controls and in patients with secondary pulmonary fibrosis, but its contribution to interstitial lung disease remains unsettled... - Best cut-off values for [14C]-urea breath tests for Helicobacter pylori detectionL Gatta
Dept. of Internal Medicine and Gastroenterology, University of Bologna, S. Orsola Hospital, Bologna, Italy
Scand J Gastroenterol 38:1144-8. 2003..5. CONCLUSION: A low dose [14C]-UBT, with a short collecting time, is a reliable method to evaluate H. pylori infection in both the pre- and post-treatment setting... - New pathophysiological mechanisms in irritable bowel syndromeG Barbara
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Aliment Pharmacol Ther 20:1-9. 2004..These novel mechanisms may aid a better understanding of the complex pathophysiology of IBS and to develop new therapies... - Functional gastrointestinal disorders and mast cells: implications for therapyG Barbara
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Neurogastroenterol Motil 18:6-17. 2006..g., second generation antihistamines, proteinase-activated receptor antagonists) may be useful pharmacological tools for these common disorders... - Review article: the pharmacological treatment of acute colonic pseudo-obstructionR De Giorgio
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Aliment Pharmacol Ther 15:1717-27. 2001..Among these agents, the potential of 5-hydroxytryptamine-4 receptor agonists and motilin receptor agonists is discussed... - Intestinal inflammation and activation of sensory nerve pathways: a functional and morphological study in the nematode infected ratR De Giorgio
Department of Internal Medicine, University of Bologna, Italy
Gut 49:822-7. 2001..As the pseudoaffective response is capsaicin sensitive, the rightward shift of the response is likely the consequence of the decrease in NK-1 receptors in the sensory pathways... - Anti-ganglioside antibodies in coeliac disease with neurological disordersU Volta
Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Building 11, St Orsola Malpighi Hospital, Via Massarenti, 9, 40138 Bologna, Italy
Dig Liver Dis 38:183-7. 2006..Anti-ganglioside antibodies have been described in sera of coeliac patients with peripheral neuropathy and cerebellar ataxia... - A role for inflammation in irritable bowel syndrome?G Barbara
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Gut 51:i41-4. 2002..A brief review of the human and animal studies that have focused on the putative role of intestinal inflammation and infections in the pathogenesis of IBS is given... - Idiopathic achalasia is not allelic to alacrima achalasia adrenal insufficiency syndrome at the ALADIN locusG Di Nardo
Department of Internal Medicine and Gastroenterology, University of Bologna, St Orsola Malpighi Hospital, Via Massarenti, 9, I 40138 Bologna, Italy
Dig Liver Dis 37:312-5. 2005..e. alacrima, achalasia and adrenocorticotropin-resistant adrenal insufficiency with neurological impairment) have mutations of the alacrima achalasia adrenal insufficiency syndrome (AAAS) gene... - Helicobacter pylori infection and gastric function in patients with fundic atrophic gastritisA Tucci
Department of Internal Medicine and Gastroenterology, Hospital S. Orsola-Malpighi, University of Bologna, Italy
Dig Dis Sci 46:1573-83. 2001..Our data suggest that fundic atrophic gastritis represents a possible end stage of H. pylori infection, characterized by a progressive disappearance of the bacterium and a progressive deterioration of gastric functions... - [Gastroesophageal reflux disease: clinical and pathophysiological features (part I)]R Corinaldesi
Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi di Bologna, Italia
Clin Ter 158:77-83. 2007..Moreover, barium swallow X-ray, 24-h esophageal pH monitoring and gastro-esophageal manometry can be useful to support diagnosis in some unusual cases or in cases partially or unresponsive to standard pharmacologic treatment... - [Gastroesophageal reflux disease: therapeutic features (Part II)]R Corinaldesi
Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi di Bologna, Italia
Clin Ter 158:165-72. 2007..Surgery, based on anti-reflux procedures, and endoscopic approaches may have a role in the management of patients with GERD... - Determination of ReQuest-based symptom thresholds to define symptom relief in GERD clinical studiesVincenzo Stanghellini
S Orsola Malpighi University Hospital, Bologna, Italy
Digestion 75:55-61. 2007.... - Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndromeGiovanni Barbara
Department of Internal Medicine and Gastroenterology, and CRBA, University of Bologna, St Orsola Hospital, Via Massarenti 9, I 40138 Bologna, Italy
Gastroenterology 132:26-37. 2007..However, the underlying mechanisms remain unknown. We assessed the effect of mast cell mediators released from the colonic mucosa of IBS patients on the activation of rat sensory neurons in vitro... - Inflammatory neuropathies of the enteric nervous systemRoberto De Giorgio
Department of Internal Medicine and Gastroenterology, University of Bologna, St Orsola Malpighi Hospital, Via Massarenti 9, I 40138 Bologna, Italy
Gastroenterology 126:1872-83. 2004.... - Natural history of chronic idiopathic intestinal pseudo-obstruction in adults: a single center studyVincenzo Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Clin Gastroenterol Hepatol 3:449-58. 2005..Intestinal motor abnormalities have long been identified in CIIP patients. Little is known of the natural history of the disease in adults. This study evaluated the clinical course of CIIP over time... - Postinfectious irritable bowel syndromeGiovanni Barbara
Department of Internal Medicine and Gastroenterology and CRBA, University of Bologna, Bologna, Italy
J Pediatr Gastroenterol Nutr 48:S95-7. 2009..There is little evidence about a specific treatment for PI-IBS. Although probiotics and antibiotics may be promising in the prevention of PI-IBS, the efficacy of these treatments should be assessed in an ad hoc designed study... - Almost all irritable bowel syndromes are post-infectious and respond to probiotics: controversial issuesGiovanni Barbara
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Dig Dis 25:245-8. 2007..Probiotics have been claimed to be of some benefit in IBS, but the majority of studies have been performed in non-specific IBS rather than in PI-IBS and a number of issues still remain to be elucidated... - Determination of ReQuest-based symptom thresholds to define symptom relief in GERD clinical studiesVincenzo Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Malpighi University Hospital, Via Massarento 9, IT 40138 Bologna, Italy
Digestion 71:145-51. 2005.... - Clinical and morphofunctional features of idiopathic myenteric ganglionitis underlying severe intestinal motor dysfunction: a study of three casesRoberto De Giorgio
Department of Internal Medicine, University of Bologna, Italy
Am J Gastroenterol 97:2454-9. 2002..The immunosuppressive approach deserves further investigation in patients with severe gut motor abnormalities attributable to idiopathic myenteric ganglionitis... - Gut microbiota and related diseases: clinical featuresVincenzo Stanghellini
Department of Clinical Medicine, St Orsola Malpighi Hospital, University of Bologna, Building No 5, Via Massarenti, 9, 40138, Bologna, Italy
Intern Emerg Med 5:S57-63. 2010.... - Aminosalicylates and other anti-inflammatory compounds for irritable bowel syndromeGiovanni Barbara
Department of Clinical Medicine and Center for Applied Biomedical Research, University of Bologna, Bologna, Italy
Dig Dis 27:115-21. 2009.... - Anti-HuD-induced neuronal apoptosis underlying paraneoplastic gut dysmotilityRoberto De Giorgio
Department of Internal Medicine, University of Bologna, Italy
Gastroenterology 125:70-9. 2003.... - Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndromeGiovanni Barbara
Departmentof Internal Medicine and Gastroenterology, and CRBA, University of Bologna, Italy
Gastroenterology 126:693-702. 2004..We assessed colonic mast cell infiltration, mediator release, and spatial interactions with mucosal innervation and their correlation with abdominal pain in IBS patients... - How relevant is symptom evaluation in NERD?Vincenzo Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Digestion 78:11-6. 2008..Through instruments like this, our understanding of NERD and its management will certainly further improve in the years to come... - Prokinetics in the treatment of acute intestinal pseudo-obstructionRoberto De Giorgio
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna I 40138, Italy
IDrugs 7:160-5. 2004..New colokinetic agents, including 5-HT(4) receptor agonists and motilides, may represent other useful therapeutic options for Ogilvie's syndrome... - Probiotics and irritable bowel syndrome: rationale and clinical evidence for their useGiovanni Barbara
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
J Clin Gastroenterol 42:S214-7. 2008..However, these results, although encouraging, should be confirmed in larger well-designed, placebo-controlled studies. A number of open questions remain to be addressed, including the dose, type, and time of administration of probiotics... - Colonic mucosal mediators from patients with irritable bowel syndrome excite enteric cholinergic motor neuronsB Balestra
Department of Forensic Medicine, Pharmacology and Toxicology, University of Pavia, Pavia, Italy Department of Clinical Medicine and Center for Applied Biomedical Research CRBA, University of Bologna, Bologna, Italy Department of Pharmacology, University of Bologna, Bologna, Italy
Neurogastroenterol Motil 24:1118-e570. 2012..These results support the role of mucosal inflammatory mediators and mast cell activation in altered motor function of IBS... - Overlapping functional syndromes: a way forward for medical therapy?V Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Eur Rev Med Pharmacol Sci 12:138. 2008 - Chronic intestinal pseudo-obstruction related to viral infectionsR De Giorgio
Department of Clinical Medicine, University of Bologna, Bologna, Italy
Transplant Proc 42:9-14. 2010..The review thus provides some new perspectives in the pathophysiology and perhaps targeted treatment of CIIPO... - Abnormalities of somatic peptide-containing nerves supplying the pelvic floor of women with genitourinary prolapse and stress urinary incontinenceP Busacchi
Department of Obstetrics and Gynecology, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
Urology 63:591-5. 2004..CONCLUSIONS: The evidence of a reduced peptide-containing nerve supply to the perineal muscles provides a morphologic basis suggesting that neural abnormalities contribute to the pathogenesis of genital prolapse and urinary incontinence... - Upper gastrointestinal bleeding due to duodenal metastasis from primary lung carcinomaC Cremon
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Dig Liver Dis 34:141-3. 2002..Herein, we report a case of duodenal metastatic involvement leading to severe upper gastrointestinal bleeding in the absence of symptoms referable to the primary tumour... - Submucous rather than myenteric neurons are activated by mucosal biopsy supernatants from irritable bowel syndrome patientsS Buhner
Human Biology, Technische Universitat Munchen, Germany Department of Physiology, Shangdong University, Shangdong, China Department of Clinical Medicine and Center for Applied Biomedical Research CRBA, St Orsola Hospital, Bologna, Italy
Neurogastroenterol Motil 24:1134-e572. 2012..This is associated with a stronger excitation of submucous neurons by serotonin. The plexus-specific effects support the concept that altered mucosa-nerve signaling underlies disturbances in IBS... - Slow gallbladder emptying reverts to normal but small intestinal transit of a physiological meal remains slow in celiac patients during gluten-free dietF Benini
Gastroenterology Unit and Histopathology Unit, University and Spedali Civili of Brescia, Brescia, Italy
Neurogastroenterol Motil 24:100-7, e79-80. 2012..Our aims were to quantitate non-invasively small intestinal transit time and GB emptying during administration of a physiological and palatable solid meal, and to assess the effect of gluten-free diet (GFD)... - Advances in our understanding of the pathology of chronic intestinal pseudo-obstructionR De Giorgio
Department of Internal Medicine and Gastroenterology, St Orsola Malpighi Hospital, Via Massarenti, 9, I 40138 Bologna, Italy
Gut 53:1549-52. 2004..Combined clinical and histopathological studies are needed to highlight new perspectives in the understanding and management of chronic intestinal pseudo-obstruction... - Management of gastroesophageal reflux diseaseV Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Drugs Today (Barc) 39:15-20. 2003..Pantoprazole is the only PPI found not to interact with the metabolism of other drugs and is therefore the treatment of choice especially for patients with co-morbidities and co-medication... - Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptomsCesare Cremon
Department of Internal Medicine and Gastroenterology, St Orsola Hospital, Center for Applied Biomedical Research, Bologna, Italy
Am J Gastroenterol 104:392-400. 2009..However, the relative magnitude of this immune component and its correlation with gender and gastrointestinal complaints in IBS patients remains poorly elucidated... - Enteric neuroplasticity evoked by inflammationValentina Vasina
Department of Pharmacology, University of Bologna, St. Orsola-Malpighi Hospital, Italy
Auton Neurosci 126:264-72. 2006..A better comprehension of ENS plasticity during inflammation could be instrumental to develop new therapeutic options for patients with IBD and inflammatory enteric neuropathies... - A novel locus for syndromic chronic idiopathic intestinal pseudo-obstruction maps to chromosome 8q23-q24Alessia Deglincerti
Laboratory of Medical Genetics, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
Eur J Hum Genet 15:889-97. 2007..01). Our data strongly support the presence of a new genetic locus associated with CIIP, long-segment Barrett esophagus, and cardiac involvement on chromosome 8... - Chronic intestinal pseudo-obstructionRosanna F Cogliandro
Department of Internal Medicine and Gastroenterology, University of Bologna, and St Orsola Malpighi Hospital, Bologna, Italy
Best Pract Res Clin Gastroenterol 21:657-69. 2007..The main pathogenetic and clinical features of the syndrome, together with current management recommendations are reviewed in this chapter... - Dyspeptic symptoms and gastric emptying in the irritable bowel syndromeVincenzo Stanghellini
Department of Internal Medicine, S. Orsola-Malpighi University Hospital, Bologna, Italy
Am J Gastroenterol 97:2738-43. 2002..CONCLUSIONS: IBS patients without overlapping dyspepsia have normal gastric emptying of solids. A significant association exists in IBS patients between delayed gastric emptying and overlapping relevant postprandial fullness and nausea... - ReQuest: new dimensions in the assessment and management of GERDVincenzo Stanghellini
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Drugs Today (Barc) 41:7-11. 2005..Furthermore, ReQuest(TM) fulfills the criteria set by the regulatory authorities for a validated symptom-based system for use as the primary outcome measure in clinical trials of GERD therapy... - Intestinal transplantation for chronic intestinal pseudo-obstruction in adult patientsMichele Masetti
University of Modena and Reggio Emilia, Liver and Multivisceral Transplant Center, Modena, Italy
Am J Transplant 4:826-9. 2004..3% and 66.6%. Although our series is limited by the number of patients, our experience suggests that ITx transplantation should be considered in adult patients suffering from CIPO and PN life-threatening complication... - Enteric neuropathology of congenital intestinal obstruction: A case reportGiovanni Di Nardo
Department of Pediatrics, Pediatric Gastroenterology Unit, University of Rome La Sapienza, Rome, Italy
World J Gastroenterol 12:5229-33. 2006..Such ENS changes mimic neuronal abnormalities observed in intestinal pseudo-obstruction... - HOX11L1: a promoter study to evaluate possible expression defects in intestinal motility disordersMonica Fava
Laboratorio di Genetica Molecolare, Istituto G. Gaslini, Genova, Italy
Int J Mol Med 10:101-6. 2002.... - Gastroparesis Cardinal Symptom Index (GCSI): development and validation of a patient reported assessment of severity of gastroparesis symptomsDennis A Revicki
Center for Health Outcomes Research, MEDTAP International, Inc, Bethesda, MD 20814, USA
Qual Life Res 13:833-44. 2004..Patient-rated symptom assessments are needed for evaluating the effectiveness of medical treatments and for monitoring outcomes in gastroparesis... - Responsiveness and interpretation of a symptom severity index specific to upper gastrointestinal disordersDennis A Revicki
Center for Health Outcome Research, MEDTAP International, Bethesda, MD 20814, USA
Clin Gastroenterol Hepatol 2:769-77. 2004..This study evaluates responsiveness of the Patient Assessment of Gastrointestinal Disorders-Symptom Severity Index (PAGI-SYM) in gastroesophageal reflux disease (GERD) and dyspepsia... - Responsiveness and interpretation of a quality of life questionnaire specific to upper gastrointestinal disordersChristine de la Loge
Mapi Values, Lyon, France
Clin Gastroenterol Hepatol 2:778-86. 2004..CONCLUSIONS: The PAGI-QOL questionnaire is a responsive and clinically relevant instrument for assessing quality of life in patients with upper gastrointestinal disorders... - A case of paraneoplastic inflammatory neuropathy of the gastrointestinal tract related to an underlying neuroblastoma: successful management with immunosuppressive therapyAlessandra Martin
Department of Pediatric Surgery, Meyer Children's Hospital, University of Florence, Italy
J Pediatr Gastroenterol Nutr 46:457-60. 2008 - Cross-cultural development and validation of a patient self-administered questionnaire to assess quality of life in upper gastrointestinal disorders: the PAGI-QOLChristine de la Loge
Mapi Values, Lyon, France
Qual Life Res 13:1751-62. 2004.... - The construction of a new evaluative GERD questionnaire--methods and state of the artDavid Armstrong
McMaster University, Hamilton, Ont, Canada
Digestion 75:17-24. 2007.... - The construction of a new evaluative GERD questionnaire - methods and state of the artDavid Armstrong
HSC 4W8, Division of Gastroenterology, McMaster University, 1200 Mian Street West, Hamilton, Ontario L8N 3Z5, Canada
Digestion 70:71-8. 2004.... - Neurology and neuropathology of the pancreatic innervationBeatrice Salvioli
JOP 3:26-33. 2002 - Functional gastroduodenal disordersJan Tack
Department of Gastroenterology, University Hospitals Leuven, Leuven, Belgium
Gastroenterology 130:1466-79. 2006..The proposed classification requires further research and careful validation but the criteria should be of value for clinical practice; for epidemiological, pathophysiological, and clinical management studies; and for drug development... - Dyspeptic symptoms in primary care. An observational study in general practiceGiovanni Maconi
Gastrointestinal Unit, L Sacco University Hospital, Via G B Grassi 74, 20157 Milan, Italy
Eur J Gastroenterol Hepatol 14:985-90. 2002..This study describes features of dyspepsia and its relationship with demographic, clinical and socio-economic factors in patients seen by general practitioners in Italy... - 5-HT7 receptors modulate peristalsis and accommodation in the guinea pig ileumMarcello Tonini
Department of Physiological and Pharmacological Sciences, University of Pavia, Pavia, Italy
Gastroenterology 129:1557-66. 2005..In this study, we evaluated the expression of 5-HT7 receptors in the guinea pig ileum and their role in peristalsis and accommodation of the circular muscle... - Transcriptional regulation of TLX2 and impaired intestinal innervation: possible role of the PHOX2A and PHOX2B genesSilvia Borghini
Laboratorio di Genetica Molecolare, Istituto G Gaslini, Genova, Italy
Eur J Hum Genet 15:848-55. 2007.... - GERD 2003 -- a consensus on the way aheadSteven F Moss
Brown University, Providence, R.I, USA
Digestion 67:111-7. 2003..Intestinal metaplasia in the lower esophagus is probably very common. Whether and how to, first, screen for, and then, perform surveillance in Barrett's esophagus remains highly problematic and contentious... - Prevalence and socioeconomic impact of upper gastrointestinal disorders in the United States: results of the US Upper Gastrointestinal StudyMichael Camilleri
Mayo Clinic College of Medicine, Center for Enteric Neurosciences and Translational Epidemiological Research, Rochester, MN, USA
Clin Gastroenterol Hepatol 3:543-52. 2005..These upper GI symptoms were associated with significant loss of work and activity days... - Sympathetic hyperactivity in patients with ulcerative colitisSimona Maule
Autonomic Unit, S Vito Hospital, University of Turin, Turin, Italy
Clin Auton Res 17:217-20. 2007..At rest, LF/HF ratios were significantly (P < 0.05) higher in chronic UC patients (2.4 +/- 1.6) compared to controls (1.2 +/- 1.0). Our results suggest a higher sympathetic tone at rest in patients with chronic UC...