R Soffietti

Summary

Affiliation: University of Turin
Country: Italy

Publications

  1. ncbi request reprint Management of brain metastases
    Riccardo Soffietti
    II Division of Neurology, Dept Neuroscience, University and San Giovanni Battista, Hospital, V Cherasco 15, 10126, Torino, Italy
    J Neurol 249:1357-69. 2002
  2. ncbi request reprint EFNS Guidelines on diagnosis and treatment of brain metastases: report of an EFNS Task Force
    R Soffietti
    Department of Neurology and Oncology, San Giovanni Battista Hospital and University, Torino, Italy
    Eur J Neurol 13:674-81. 2006
  3. ncbi request reprint [Future prospects]
    Riccardo Soffietti
    Unità Operativa di Neuro Oncologia, Dipartimento di Neuroscienze e Dipartimento di Oncologia, ASO San Giovani Battista e Università di Torino
    Tumori 93:suppl 14-5. 2007
  4. ncbi request reprint New chemotherapy options for the treatment of malignant gliomas
    Riccardo Soffietti
    Division of Neuro Oncology, Departments of Neuroscience and Oncology, University and San Giovanni Battista Hospital, Turin, Italy
    Anticancer Drugs 18:621-32. 2007
  5. ncbi request reprint Neuro-oncology: new insights and advances in treatment
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience, University and San Giovanni Battista Hospital, Torino, Italy
    Lancet Neurol 7:14-6. 2008
  6. pmc Bevacizumab and fotemustine for recurrent glioblastoma: a phase II study of AINO (Italian Association of Neuro-Oncology)
    Riccardo Soffietti
    Dept Neuro Oncology, University and City of Health and Science Hospital of Turin, Via Cherasco 15, 10126, Turin, Italy
    J Neurooncol 116:533-41. 2014
  7. doi request reprint Neurologic complications of chemotherapy and other newer and experimental approaches
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience, University and San Giovanni Battista Hospital, Turin, Italy Electronic address
    Handb Clin Neurol 121:1199-218. 2014
  8. doi request reprint Targeted therapy in brain metastasis
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience, University and San Giovanni Battista Hospital, Torino, Italy
    Curr Opin Oncol 24:679-86. 2012
  9. doi request reprint A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three brain metastases from solid tumors after surgical resection or radiosurgery: quality-of-life
    Riccardo Soffietti
    University of Torino and San Giovanni Battista Hospital, Turin, Italy
    J Clin Oncol 31:65-72. 2013
  10. ncbi request reprint Anti-angiogenic approaches to malignant gliomas
    R Soffietti
    Division of Neuro Oncology, Dept Neuroscience, University and San Giovanni Hospital, Torino, Italy
    Curr Cancer Drug Targets 12:279-88. 2012

Detail Information

Publications26

  1. ncbi request reprint Management of brain metastases
    Riccardo Soffietti
    II Division of Neurology, Dept Neuroscience, University and San Giovanni Battista, Hospital, V Cherasco 15, 10126, Torino, Italy
    J Neurol 249:1357-69. 2002
    ..New radiosensitizers and cytotoxic or cytostatic agents, and innovative technique of drug delivery are being investigated...
  2. ncbi request reprint EFNS Guidelines on diagnosis and treatment of brain metastases: report of an EFNS Task Force
    R Soffietti
    Department of Neurology and Oncology, San Giovanni Battista Hospital and University, Torino, Italy
    Eur J Neurol 13:674-81. 2006
    ..WBRT alone is the treatment of choice for patients with single or multiple brain metastases not amenable to surgery or radiosurgery. Chemotherapy may be the initial treatment for patients with brain metastases from chemosensitive tumors...
  3. ncbi request reprint [Future prospects]
    Riccardo Soffietti
    Unità Operativa di Neuro Oncologia, Dipartimento di Neuroscienze e Dipartimento di Oncologia, ASO San Giovani Battista e Università di Torino
    Tumori 93:suppl 14-5. 2007
  4. ncbi request reprint New chemotherapy options for the treatment of malignant gliomas
    Riccardo Soffietti
    Division of Neuro Oncology, Departments of Neuroscience and Oncology, University and San Giovanni Battista Hospital, Turin, Italy
    Anticancer Drugs 18:621-32. 2007
    ....
  5. ncbi request reprint Neuro-oncology: new insights and advances in treatment
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience, University and San Giovanni Battista Hospital, Torino, Italy
    Lancet Neurol 7:14-6. 2008
  6. pmc Bevacizumab and fotemustine for recurrent glioblastoma: a phase II study of AINO (Italian Association of Neuro-Oncology)
    Riccardo Soffietti
    Dept Neuro Oncology, University and City of Health and Science Hospital of Turin, Via Cherasco 15, 10126, Turin, Italy
    J Neurooncol 116:533-41. 2014
    ..Future studies should explore alternative regimens of combination of the two drugs...
  7. doi request reprint Neurologic complications of chemotherapy and other newer and experimental approaches
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience, University and San Giovanni Battista Hospital, Turin, Italy Electronic address
    Handb Clin Neurol 121:1199-218. 2014
    ..Last, the so-called "chemobrain" is an emerging issue, as it is a model of a subtle of and long-lasting damage to neuronal structures from some antineoplastic agents. ..
  8. doi request reprint Targeted therapy in brain metastasis
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience, University and San Giovanni Battista Hospital, Torino, Italy
    Curr Opin Oncol 24:679-86. 2012
    ..To review the state of the art and new developments in the field of targeted agents for brain metastases...
  9. doi request reprint A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three brain metastases from solid tumors after surgical resection or radiosurgery: quality-of-life
    Riccardo Soffietti
    University of Torino and San Giovanni Battista Hospital, Turin, Italy
    J Clin Oncol 31:65-72. 2013
    ..Here, we report the health-related quality-of-life (HRQOL) results...
  10. ncbi request reprint Anti-angiogenic approaches to malignant gliomas
    R Soffietti
    Division of Neuro Oncology, Dept Neuroscience, University and San Giovanni Hospital, Torino, Italy
    Curr Cancer Drug Targets 12:279-88. 2012
    ..Other promising antiangiogenic compounds are cilengitide and continuous temozolomide. Toxicity is acceptable. Open issues are represented by patterns of tumor progression, resistance mechanisms and biomarkers...
  11. ncbi request reprint New developments in the treatment of malignant gliomas
    Riccardo Soffietti
    University and San Giovanni Battista Hospital, Division of Neuro Oncology, Department of Neuroscience, Turin, Italy
    Expert Rev Neurother 7:1313-26. 2007
    ....
  12. doi request reprint Brain metastases: current management and new developments
    Riccardo Soffietti
    Division of Neuro Oncology, Department of Neuroscience and Oncology, University and San Giovanni Battista Hospital, Turin, Italy
    Curr Opin Oncol 20:676-84. 2008
    ..To review the state-of-the-art and new developments in the management of patients with brain metastases...
  13. doi request reprint The role of intra-cerebrospinal fluid treatment and prophylaxis in patients with solid tumors
    Riccardo Soffietti
    Department of Neuroscience, University and San Giovanni Battista Hospital, Torino, Italy
    Semin Oncol 36:S55-68. 2009
    ..This review discusses clinical situations in which treatment or chemoprophylaxis of CNS metastases and NM from breast or lung cancer may play an important role. Potential clinical trials to assess these assumptions also will be proposed...
  14. doi request reprint Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force
    R Soffietti
    Department of Neuroscience, University Hospital San Giovanni Battista, Turin, Italy
    Eur J Neurol 17:1124-33. 2010
    ..Diffuse infiltrative low-grade gliomas of the cerebral hemispheres in the adult are a group of tumors with distinct clinical, histological and molecular characteristics, and there are still controversies in management...
  15. ncbi request reprint Second-line treatment with carboplatin for recurrent or progressive oligodendroglial tumors after PCV (procarbazine, lomustine, and vincristine) chemotherapy: a phase II study
    Riccardo Soffietti
    Neuro Oncology Service, Department of Neuroscience, San Giovanni Battista Hospital, University of Turin, Turin, Italy
    Cancer 100:807-13. 2004
    ..In the current study, the authors investigated the use of carboplatin as a second-line chemotherapeutic agent against these types of tumors...
  16. ncbi request reprint Radiotherapy and chemotherapy of brain metastases
    R Soffietti
    Neuro Oncology Service, Department of Neuroscience, University and Azienda Ospedaliera San Giovanni Battista, Torino, Italy
    J Neurooncol 75:31-42. 2005
    ..Increasingly, the different treatments are tailored to the different prognostic subgroups, as defined by Radiation Therapy Oncology Group RPA Classes...
  17. ncbi request reprint Chemotherapy of anaplastic oligodendroglial tumours
    Riccardo Soffietti
    Department of Neuroscience, University and S Giovanni Battista Hospital, Torino, Italy
    Expert Opin Pharmacother 5:295-306. 2004
    ..Molecular genetic analysis is increasingly employed for both diagnostic and prognostic purposes. Loss of heterozygosity on 1p and 19q is the key alteration for predicting the prognosis and the response to chemotherapy...
  18. ncbi request reprint Brain metastases from unknown primary tumour: a prospective study
    R Ruda
    Department of Neuroscience, University of Torino, Italy
    J Neurol 248:394-8. 2001
    ..Only a few asymptomatic patients may benefit from an early detection and treatment of the primary tumour during the follow-up...
  19. ncbi request reprint Proliferating cell nuclear antigen (PCNA) in low-grade astrocytomas: its prognostic significance
    M C Vigliani
    II Department of Neurology, University of Turin, Italy
    Tumori 80:295-300. 1994
    ..001). CONCLUSION: These data suggest that PCNA immunostaining can be a useful tool to define the prognosis of low-grade astrocytomas on routine biopsy material...
  20. ncbi request reprint [Cerebral metastatis. Diagnostic and therapeutic features]
    R Soffietti
    Sezione di Neurologia, Dipartimento di Neuroscienze, Universita, Torino
    Recenti Prog Med 91:327-31. 2000
    ..Chemotherapy is a valid option only in cases of metastases from chemosensitive neoplasms (small-cell lung tumors or breast tumors)...
  21. ncbi request reprint Primitive cerebral melanoma: case report and review of the literature
    S Greco Crasto
    Section of Neuroradiology, Department of Neuroscience, University of Turin, Turin, Italy
    Surg Neurol 55:163-8; discussion 168. 2001
    ..The prognosis of cerebral primitive melanoma is variable, although it is common opinion that primitive cerebral melanoma has a better prognosis than cutaneous melanoma, with two cases in the literature surviving 9 and 12 years...
  22. doi request reprint Caveolin 1 expression independently predicts shorter survival in oligodendrogliomas
    Rebecca Senetta
    Department of Biomedical Sciences, University of Turin, Italy
    J Neuropathol Exp Neurol 68:425-31. 2009
    ..015). These data are the first evidence that cav-1 immunohistochemistry is an independent prognostic marker in tumors with an oligodendroglial component regardless of the 1p/19q status...
  23. ncbi request reprint Endocrine dysfunction in patients operated on for non-pituitary intracranial tumors
    H J Schneider
    Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Italy
    Eur J Endocrinol 155:559-66. 2006
    ..The aim of this study was to assess the presence of endocrine alterations in patients operated on for intracranial tumors...
  24. ncbi request reprint Primary lymphomas of the brain: a clinico-pathologic review of 37 cases
    D Schiffer
    II Neurological Clinic, University of Turin, Italy
    Tumori 73:585-92. 1987
    ..01). The prognosis of lymphomas of the CNS, even if radioresponsive tumors, remains poor. Most patients relapse after treatment, most often locally in the brain, with a variable frequency of spinal or systemic localization...
  25. ncbi request reprint Brain metastases
    R Soffietti
    Division of Neuro Oncology, University and San Giovanni Battista Hospital, Turin, Italy
    Handb Clin Neurol 105:747-55. 2012
    ..New radiosensitizers, targeted agents, and innovative techniques of drug delivery are being investigated...
  26. doi request reprint Epilepsy and brain tumors
    Roberta Ruda
    Division of Neuro Oncology, Department of Neuroscience, San Giovanni Battista Hospital and University of Torino, Torino, Italy
    Curr Opin Oncol 22:611-20. 2010
    ..To present an overview of the recent findings in pathophysiology and management of epileptic seizures in patients with brain tumors...