Salvatore Santo Signorelli

Summary

Affiliation: University of Catania
Country: Italy

Publications

  1. ncbi Study on unrecognized peripheral arterial disease (PAD) by ankle/brachial index and arterial comorbidity in Catania, Sicily, Italy
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Internal Medicine and Vascular Medicine, University of Catania, Italy
    Angiology 61:524-9. 2010
  2. ncbi Inflammation in peripheral arterial disease (PAD)
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, School of Medicine, University of Catania, Italy
    Curr Pharm Des 18:4350-7. 2012
  3. ncbi Patients with unrecognized peripheral arterial disease (PAD) assessed by ankle-brachial index (ABI) present a defined profile of proinflammatory markers compared to healthy subjects
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Internal Medicine and Vascular Medicine, School of Medicine, University of Catania, Italy
    Cytokine 59:294-8. 2012
  4. ncbi High circulating levels of cytokines (IL-6 and TNFalpha), adhesion molecules (VCAM-1 and ICAM-1) and selectins in patients with peripheral arterial disease at rest and after a treadmill test
    Salvatore Santo Signorelli
    Department of Internal Medicine and Medical Specialties, Faculty of Medicine, University of Catania, Catania, Italy
    Vasc Med 8:15-9. 2003
  5. ncbi High frequency of Chlamydophila pneumoniae infections: patients with peripheral arterial disease and those with risk factors for cardiovascular diseases compared to normal subjects
    S S Signorelli
    Department of Internal Medicine and Systemic Diseases, University of Catania Italy
    J Chemother 22:392-6. 2010
  6. ncbi Prevalence of high ankle-brachial index (ABI) in general population of Southern Italy, risk factor profiles and systemic cardiovascular co-morbidity: an epidemiological study
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Diseases, Section for Internal and Vascular Medicine, University of Catania, Medical Angiology Unit, Garibaldi Hospital, Piazza S Maria di Gesù 5, I 95123 Catania, Italy
    Arch Gerontol Geriatr 53:55-9. 2011
  7. ncbi Effects of long-term hormone replacement therapy: results from a cohort study
    S S Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Internal and Vascular Medicine, Faculty of Medicine, University of Catania, Catania, Italy
    J Endocrinol Invest 34:180-4. 2011
  8. ncbi Polymorphisms of steroid 5-alpha-reductase type I (SRD5A1) gene are associated to peripheral arterial disease
    S S Signorelli
    Department of Internal Medicine and Systemic Disease, Medical Angiology Section, Faculty of Medicine, University of Catania, Catania, Italy
    J Endocrinol Invest 31:1092-7. 2008
  9. ncbi Propionyl-L-carnitine therapy: effects on endothelin-1 and homocysteine levels in patients with peripheral arterial disease and end-stage renal disease
    Salvatore Santo Signorelli
    Medical Angiology Section, Department of Internal Medicine and Systemic Pathology, University of Catania, Catania, Italy
    Kidney Blood Press Res 29:100-7. 2006
  10. ncbi A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Pathology, Medical Angiology Section, University of Catania, Catania, Italy
    Drugs Aging 23:263-70. 2006

Collaborators

Detail Information

Publications15

  1. ncbi Study on unrecognized peripheral arterial disease (PAD) by ankle/brachial index and arterial comorbidity in Catania, Sicily, Italy
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Internal Medicine and Vascular Medicine, University of Catania, Italy
    Angiology 61:524-9. 2010
    ..Unrecognized PAD shows significant arterial co-morbidities and the ABI is a useful method to screen asymptomatic PAD...
  2. ncbi Inflammation in peripheral arterial disease (PAD)
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, School of Medicine, University of Catania, Italy
    Curr Pharm Des 18:4350-7. 2012
    ..Finally, efforts must be made towards addressing this very important objective, and consequently a greater number of studies need to be made in combatting phlogosis, especially among PAD patients...
  3. ncbi Patients with unrecognized peripheral arterial disease (PAD) assessed by ankle-brachial index (ABI) present a defined profile of proinflammatory markers compared to healthy subjects
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Internal Medicine and Vascular Medicine, School of Medicine, University of Catania, Italy
    Cytokine 59:294-8. 2012
    ..Many studies have postulated that atherosclerosis should be considered as an inflammatory disease. In addition, some studies have focused on the relationship between inflammation and peripheral arterial disease (PAD)...
  4. ncbi High circulating levels of cytokines (IL-6 and TNFalpha), adhesion molecules (VCAM-1 and ICAM-1) and selectins in patients with peripheral arterial disease at rest and after a treadmill test
    Salvatore Santo Signorelli
    Department of Internal Medicine and Medical Specialties, Faculty of Medicine, University of Catania, Catania, Italy
    Vasc Med 8:15-9. 2003
    ..001 or 0.0001, controls p < 0.05 or 0.001). These results confirm that white blood cell activation is characteristic of systemic atherosclerosis and that these inflammation markers increase in conditions of hemodynamic stress...
  5. ncbi High frequency of Chlamydophila pneumoniae infections: patients with peripheral arterial disease and those with risk factors for cardiovascular diseases compared to normal subjects
    S S Signorelli
    Department of Internal Medicine and Systemic Diseases, University of Catania Italy
    J Chemother 22:392-6. 2010
    ..pneumoniae infection is frequent in peripheral arterial disease patients and we believe that it could be considered as an additional risk factor involved in the pathogenesis of this disease...
  6. ncbi Prevalence of high ankle-brachial index (ABI) in general population of Southern Italy, risk factor profiles and systemic cardiovascular co-morbidity: an epidemiological study
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Diseases, Section for Internal and Vascular Medicine, University of Catania, Medical Angiology Unit, Garibaldi Hospital, Piazza S Maria di Gesù 5, I 95123 Catania, Italy
    Arch Gerontol Geriatr 53:55-9. 2011
    ..Further studies are needed to clarify this evidence, a longitudinal observation of this clinical outcome, as we are performing, could provide a number of interesting elements...
  7. ncbi Effects of long-term hormone replacement therapy: results from a cohort study
    S S Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Internal and Vascular Medicine, Faculty of Medicine, University of Catania, Catania, Italy
    J Endocrinol Invest 34:180-4. 2011
    ..Furthermore, this study underlines the real-life clinical experience of a Menopause Center...
  8. ncbi Polymorphisms of steroid 5-alpha-reductase type I (SRD5A1) gene are associated to peripheral arterial disease
    S S Signorelli
    Department of Internal Medicine and Systemic Disease, Medical Angiology Section, Faculty of Medicine, University of Catania, Catania, Italy
    J Endocrinol Invest 31:1092-7. 2008
    ..Since the examined SRDA1 gene variant was previously associated with a low enzymatic activity, we suggest that a decreased local enzymatic conversion of testosterone may contribute to PAD genetic susceptibility...
  9. ncbi Propionyl-L-carnitine therapy: effects on endothelin-1 and homocysteine levels in patients with peripheral arterial disease and end-stage renal disease
    Salvatore Santo Signorelli
    Medical Angiology Section, Department of Internal Medicine and Systemic Pathology, University of Catania, Catania, Italy
    Kidney Blood Press Res 29:100-7. 2006
    ..We aimed to explore the therapeutic role of propionyl-L-carnitine (PLC) in hemodialysis patients with PAD by measuring ankle/brachial index (ABI), ET-1 and Hcy...
  10. ncbi A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Pathology, Medical Angiology Section, University of Catania, Catania, Italy
    Drugs Aging 23:263-70. 2006
    ..We explored the efficacy of intravenous therapy with propionyl L-carnitine in patients with both peripheral arterial disease (PAD) and chronic renal insufficiency requiring haemodialysis...
  11. ncbi Effect of PLC on functional parameters and oxidative profile in type 2 diabetes-associated PAD
    Signorelli Salvatore Santo
    Department of Internal Medicine and Systemic Pathology, Medical Angiology Section, Italy
    Diabetes Res Clin Pract 72:231-7. 2006
    ....
  12. ncbi Behaviour of some indicators of oxidative stress in postmenopausal and fertile women
    Salvatore Santo Signorelli
    Department of Internal Medicine and Systemic Disease, Section of Medical Angiology, Faculty of Medicine, University of Catania, Via Firenze 123, 95020 Acicastello CT, Italy
    Maturitas 53:77-82. 2006
    ..Oxidative stress is involved in the pathophysiology of atherosclerosis and our study aim was to assess the presence of such stress in postmenopausal women...
  13. ncbi Plasma levels and zymographic activities of matrix metalloproteinases 2 and 9 in type II diabetics with peripheral arterial disease
    Salvatore Santo Signorelli
    Departments of Internal Medicine, School of Medicine, University of Catania, Catania, Italy
    Vasc Med 10:1-6. 2005
    ..In particular, plasma MMP-9 may be a useful marker for the development of vascular disease in type II diabetics...
  14. ncbi Correlation between some metabolic markers of vascular risk and carotid artery intima-media thickness in postmenopausal women
    Salvatore Santo Signorelli
    Department of Internal Medicine and Medical Specialities, Faculty of Medicine, University of Catania, Catania, Italy
    Maturitas 49:134-9. 2004
    ....
  15. ncbi Neopterin: A potential marker in chronic peripheral arterial disease
    Salvatore Santo Signorelli
    Department of Medical and Pediatric Science, Section of Internal and Vascular Medicine, University of Catania, Catania I 95125, Italy
    Mol Med Rep 7:1855-8. 2013
    ..The results of the present study showed that neopterin plasma levels were statistically different among the groups. These findings demonstrated that activation of N‑mediated monocyte‑macrophage, was also observed in chronic PAD...