Research Topics
| B SerioloSummaryAffiliation: University of Genoa Country: Italy Publications
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Detail Information
Publications
Serum prolactin concentrations in male patients with rheumatoid arthritisBruno Seriolo
Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, 16132 Genova, Italy
Ann N Y Acad Sci 966:258-62. 2002..The serum PRL concentration was found to be increased in relation to the duration and the activity of the disease. Serum PRL levels do not seem to have any relationship with the BMD, at least in RA...
Serum osteocalcin levels in premenopausal rheumatoid arthritis patientsBruno Seriolo
Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 966:502-7. 2002..This study suggests that generalized bone loss occurs in active RA and is characterized by an evident bone resorption correlated with the high levels of inflammation...
Effects of anti-TNF-alpha treatment on lipid profile in patients with active rheumatoid arthritisBruno Seriolo
Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 1069:414-9. 2006..The atherogenic index showed no changes during the study. Therefore, anti-TNF-alpha treatment might affect lipid profile in RA patients...
Bone metabolism changes during anti-TNF-alpha therapy in patients with active rheumatoid arthritisBruno Seriolo
Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 1069:420-7. 2006..e., TNF-alpha) cytokine effects on bone metabolism...
[Are there any positive effects of TNF-alpha blockers on bone metabolism?]B Seriolo
Clinica Reumatologica, Dipartimento Medicina Interna e Specialità Mediche, Universita di Genova, Italia
Reumatismo 58:199-205. 2006..Treatment with TNF-alpha blockers, might influence bone metabolism and prevent structural bone damage in RA, in particular at the periarticular regions...
[Rheumatoid arthritis and atherosclerosis]B Seriolo
Clinica Reumatologica, Dipartimento di Medicina Interna e Specialita Mediche, Universita di Genova, Genova, Italia
Reumatismo 55:140-6. 2003..In addition, other studies indicate that serum concentration of pro-inflammatory cytokines are found elevated at baseline, among patients at risk for future coronary occlusion...
Homocysteine and antiphospholipid antibodies in rheumatoid arthritis patients: relationships with thrombotic eventsB Seriolo
Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Clin Exp Rheumatol 19:561-4. 2001..To investigate the possible relationships between plasma homocysteine levels and thrombotic events in a select population of rheumatoid arthritis (RA) patients with or without antiphospholipid (aPL) antibody positivity...
Serum cytokines and steroidal hormones in polymyalgia rheumatica and elderly-onset rheumatoid arthritisM Cutolo
Department of Internal Medicine, Research Laboratory and Division of Rheumatology, University Hospital San Martino, Viale Benedetto XV no 6, 16132 Genova, Italy
Ann Rheum Dis 65:1438-43. 2006..Polymyalgia rheumatica (PMR) may create some difficulties in the differential diagnosis of elderly-onset rheumatoid arthritis (EORA) and of EORA with PMR-like onset (EORA/PMR)...
The hypothalamic-pituitary-adrenal and gonadal axes in rheumatoid arthritisM Cutolo
Division of Rheumatology, Department of Internal Medicine, University of Genova, Italy
Ann N Y Acad Sci 917:835-43. 2000..The interactions between the immunological and neuroendocrine circuits is the subject of active and extensive ongoing research and might in the near future offer highly promising strategies for hormone-replacement therapies in RA...
Circadian rhythms in RAM Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 6 16132 Genova, Italy
Ann Rheum Dis 62:593-6. 2003
Melatonin serum levels in rheumatoid arthritisA Sulli
Laboratory and Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 966:276-83. 2002....
Altered circadian rhythms in rheumatoid arthritis patients play a role in the disease's symptomsM Cutolo
Research Laboratory and Division of Rheumatology, Department of Immunology and Endocrinology, University of Genova, Italy Viale Benedetto XV, 16132 Genova I, Italy
Autoimmun Rev 4:497-502. 2005....
Sex hormones influence on the immune system: basic and clinical aspects in autoimmunityM Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genova, Italy
Lupus 13:635-8. 2004..In conclusion, locally increased estrogens (i.e., synovial tissue in RA or skin in SLE) might exert activating effects on cell proliferation, including macrophages and fibroblasts, suggesting new roles for estrogens in autoimmunity...
Circannual vitamin d serum levels and disease activity in rheumatoid arthritis: Northern versus Southern EuropeM Cutolo
Division of Rheumatology Dept Internal Medicine, University of Genova, Genova, Italy
Clin Exp Rheumatol 24:702-4. 2006..Greater intake of vitamin D has been associated with a lower risk of rheumatoid arthritis (RA) and low serum vitamin D together with higher prevalence of RA seem common among North European people when compared to Southern Europe...
Methotrexate in psoriatic arthritisM Cutolo
Research Laboratory, Division of Rheumatology, Department of Internal Medicine, University of Genova, Italy
Clin Exp Rheumatol 20:S76-80. 2002..The concomitant use of folic acid reduces both the frequency of serum liver enzyme level increases but also the efficacy of MTX by competing with the folate receptors...
Endothelin and sex hormones modulate the fibronectin synthesis by cultured human skin scleroderma fibroblastsS Soldano
Research Laboratories and Clinical Academic Unit of Rheumatology, Department of Internal Medicine, University of Genova, Italy
Ann Rheum Dis 68:599-602. 2009..To evaluate the influence of endothelin-1 (ET-1) and sex hormones on cell proliferation and extracellular matrix (ECM) synthesis (ie, fibronectin, laminin) by cultured normal and scleroderma (SSc) human skin fibroblasts (FBs)...
Endothelin receptor antagonists: effects on extracellular matrix synthesis in primary cultures of skin fibroblasts from systemic sclerosis patientsS Soldano
Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova
Reumatismo 64:326-34. 2012..In conclusion, ET-1 antagonism might have positive effects in contrasting the profibrotic activity of systemic sclerosis skin fibroblasts...
Nailfold videocapillaroscopic patterns and serum autoantibodies in systemic sclerosisM Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy
Rheumatology (Oxford) 43:719-26. 2004....
Cortisol, dehydroepiandrosterone sulfate, and androstenedione levels in patients with polymyalgia rheumatica during twelve months of glucocorticoid therapyM Cutolo
Laboratory and Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Italy
Ann N Y Acad Sci 966:91-6. 2002....
Estrogens, autoimmunity and the heartM Cutolo
Research Laboratory, Division of Rheumatology, Department of Internal Medicine, University of Genova, Italy
Lupus 14:675-8. 2005..New roles for estrogen peripheral metabolites (hydroxylated) and their increased formation in inflammatory sites, might partially introduce some explanations for several apparently contrasting evidences...
[Nailfold videocapillaroscopy in systemic sclerosis: diagnostic and follow-up parameters and correlation with both specific serum autoantibodies and subsets of skin involvement]A Sulli
Divisione di Reumatologia, Dipartimento di Medicina Interna, Universita degli Studi di Genova, Genoa
Reumatismo 56:36-45. 2004..The presence of the different subsets of skin involvement (limSS and difSS), as well as the role of some specific serum autoantibodies in the expression of the NVC parameters were investigated...
Anti-inflammatory effects of leflunomide in combination with methotrexate on co-culture of T lymphocytes and synovial macrophages from rheumatoid arthritis patientsM Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genoa, Viale Benedetto XV, 6 16132 Genoa, Italy
Ann Rheum Dis 65:728-35. 2006....
Macroamylasemia: a possible cause of unexplained hyperamylasemia in rheumatoid arthritisM Cutolo
Division of Rheumatology, University of Genova, Italy
Br J Rheumatol 34:290-2. 1995..g. ultrasonography, computerized tomography) to rule out pancreatic disease, and could induce prescription of unnecessary elemental diets and replacement therapies, as reported in our patient...
Vitamin D and rheumatoid arthritis: comment on the letter by Nielen et alMaurizio Cutolo
Arthritis Rheum 56:1719-20. 2007
Effects of etanercept or infliximab treatment on lipid profile and insulin resistance in patients with refractory rheumatoid arthritisBruno Seriolo
Clin Rheumatol 26:1799-800. 2007
Vitamin D in rheumatoid arthritisMaurizio Cutolo
Research Laboratory and Academic Clinical Unit of Rheumatology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 6 16132 Genova, Italy
Autoimmun Rev 7:59-64. 2007..Recently, greater intake of vitamin D was associated with a lower risk of RA, as well as a significant clinical improvement was strongly correlated with the immunomodulating potential in vitamin D-treated RA patients...
Longterm anti-tumor necrosis factor-alpha treatment in patients with refractory rheumatoid arthritis: relationship between insulin resistance and disease activityBruno Seriolo
J Rheumatol 35:355-7. 2008
Adrenal gland hypofunction in active polymyalgia rheumatica. effect of glucocorticoid treatment on adrenal hormones and interleukin 6Maurizio Cutolo
Department of Internal Medicine and Medical Specialities, University of Genova, Italy
J Rheumatol 29:748-56. 2002....
Androgens and estrogens modulate the immune and inflammatory responses in rheumatoid arthritisMaurizio Cutolo
Laboratory and Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 966:131-42. 2002....
Modulation of cell growth and apoptosis by sex hormones in cultured monocytic THP-1 cellsMaurizio Cutolo
Laboratory and Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 966:204-10. 2002..In conclusion, these results support the possibility of sex hormone modulation of apoptosis in macrophage-like cells, with interesting therapeutic perspectives in rheumatoid arthritis...
Antiproliferative-antiinflammatory effects of methotrexate and sex hormones on cultured differentiating myeloid monocytic cells (THP-1)Maurizio Cutolo
Laboratory and Division of Rheumatology, Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
Ann N Y Acad Sci 966:232-7. 2002..Therefore, the enhancing antiinflammatory effects exerted by androgens might represent a further explanation for the reduced frequency of inflammatory diseases in male subjects...
Anti-TNF and sex hormonesMaurizio Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine University of Genova, Viale Benedetto XV6, 16132, Genova, Italy
Ann N Y Acad Sci 1069:391-400. 2006..In patients with at least long-standing RA, this indicates that alterations of serum sex hormones and altered activity of respective converting enzymes are imprinted for a long-lasting period over at least 12 weeks...
Glucocorticoid effects on adrenal steroids and cytokine responsiveness in polymyalgia rheumatica and elderly onset rheumatoid arthritisAlberto Sulli
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, San Martino Hospital, University of Genova, Viale Benedetto XV, 6 16132 Genova, Italy
Ann N Y Acad Sci 1069:307-14. 2006..Interestingly, in PMR and EORA/PMR patients, GC treatment was found to downregulate PRG serum levels...
Circadian rhythms: glucocorticoids and arthritisMaurizio Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genova, Viale Benedetto XV6, 16132 Genova, Italy
Ann N Y Acad Sci 1069:289-99. 2006..In conclusion, the right timing (early morning) for the glucocorticoid therapy in arthritis is fundamental and well justified by the circadian rhythms of the inflammatory mechanisms...
Sex hormones and rheumatoid arthritisMaurizio Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genova, Viale Benedetto XV 6, 16132 Genova, Italy
Autoimmun Rev 1:284-9. 2002..Local increased estrogen concentrations and decreased androgen levels have been observed in RA synovial fluids and seem to play a more important role in the immune/inflammatory local response...
Anti-citrulline antibodies in psoriatic patients with and without arthritisAurora Parodi
Acta Derm Venereol 85:253-4. 2005
Synovial fluid estrogens in rheumatoid arthritisMaurizio Cutolo
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, University of Genova, Viale Bebedetto XV, 6, Genova 16132, Italy
Autoimmun Rev 3:193-8. 2004..e. SF in RA) of 16alpha-hydroxyestrone or 2-hydroxyestrogens...
