Leonardo-A Sechi

Summary

Affiliation: University of Sassari
Country: Italy

Publications

  1. pmc Linking chronic infection and autoimmune diseases: Mycobacterium avium subspecies paratuberculosis, SLC11A1 polymorphisms and type-1 diabetes mellitus
    Daniela Paccagnini
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia clinica e sperimentale, Sassari, Italy
    PLoS ONE 4:e7109. 2009
  2. pmc Specific immunoassays confirm association of Mycobacterium avium Subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus
    Valentina Rosu
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia, Universita degli Studi di Sassari, Sassari, Italy
    PLoS ONE 4:e4386. 2009
  3. pmc Mycobacterium avium subsp. paratuberculosis in an Italian cohort of type 1 diabetes pediatric patients
    Maria Luisa Manca Bitti
    Pediatric Diabetology Unit, Policlinico di Tor Vergata, University of Rome Tor Vergata, 00133 Rome, Italy
    Clin Dev Immunol 2012:785262. 2012
  4. pmc Zinc transporter 8 and MAP3865c homologous epitopes are recognized at T1D onset in Sardinian children
    Speranza Masala
    Universita degli Studi di Sassari, Dipartimento di Scienze Biomediche, Sezione di Microbiologia e Virologia, Sassari, Sardinia, Italy
    PLoS ONE 8:e63371. 2013
  5. pmc Association of Mycobacterium avium subsp. paratuberculosis with multiple sclerosis in Sardinian patients
    Davide Cossu
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia e Virologia, Universita di Sassari, Sassari, Italy
    PLoS ONE 6:e18482. 2011
  6. pmc In vitro cytokine profiles and viability of different human cells treated with whole cell lysate of Mycobacterium avium subsp. paratuberculosis
    Pittu Sandhya Rani
    Pathogen Biology Laboratory, Department of Biotechnology, School of Life Sciences, University of Hyderabad, Hyderabad, India
    Gut Pathog 4:10. 2012
  7. pmc Gene expression profiling of Mycobacterium avium subsp. paratuberculosis in simulated multi-stress conditions and within THP-1 cells reveals a new kind of interactive intramacrophage behaviour
    Andrea Cossu
    Department of Biomedical Sciences, Division of Experimental and Clinical Microbiology, University of Sassari, Sassari, Italy
    BMC Microbiol 12:87. 2012
  8. pmc Sardinian Type 1 diabetes patients, Transthyretin and Mycobacterium avium subspecies paratuberculosis infection
    Speranza Masala
    Department of Biomedical Sciences, Division of Experimental and Clinical Microbiology, University of Sassari, Sassari, Italy
    Gut Pathog 4:24. 2012
  9. pmc Interaction between Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium avium subspecies paratuberculosis with the enteric glia and microglial cells
    Sara Cannas
    Dipartimento di Scienze Biomediche Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Italy
    Gut Pathog 3:19. 2011
  10. pmc Comparative genomics of Helicobacter pylori isolates recovered from ulcer disease patients in England
    Farhana Kauser
    Pathogen Evolution Group, Laboratory of Molecular and Cell Biology, Centre for DNA Fingerprinting and Diagnostics CDFD, Hyderabad, India
    BMC Microbiol 5:32. 2005

Collaborators

Detail Information

Publications57

  1. pmc Linking chronic infection and autoimmune diseases: Mycobacterium avium subspecies paratuberculosis, SLC11A1 polymorphisms and type-1 diabetes mellitus
    Daniela Paccagnini
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia clinica e sperimentale, Sassari, Italy
    PLoS ONE 4:e7109. 2009
    ..Mycobacterium avium subsp. paratuberculosis (MAP) has been reported to be a possible trigger in the development of T1DM...
  2. pmc Specific immunoassays confirm association of Mycobacterium avium Subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus
    Valentina Rosu
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia, Universita degli Studi di Sassari, Sassari, Italy
    PLoS ONE 4:e4386. 2009
    ..Rapid identification of infectious agents such as MAP in diabetic patients at the level of clinics might be helpful in deciphering the role of chronic bacterial infection in the development of autoimmune diseases such as T1DM...
  3. pmc Mycobacterium avium subsp. paratuberculosis in an Italian cohort of type 1 diabetes pediatric patients
    Maria Luisa Manca Bitti
    Pediatric Diabetology Unit, Policlinico di Tor Vergata, University of Rome Tor Vergata, 00133 Rome, Italy
    Clin Dev Immunol 2012:785262. 2012
    ....
  4. pmc Zinc transporter 8 and MAP3865c homologous epitopes are recognized at T1D onset in Sardinian children
    Speranza Masala
    Universita degli Studi di Sassari, Dipartimento di Scienze Biomediche, Sezione di Microbiologia e Virologia, Sassari, Sardinia, Italy
    PLoS ONE 8:e63371. 2013
    ..It would be relevant to investigate larger cohorts of children, followed over time, to elucidate whether Ab titers against these MAP/Znt8 epitopes wane after diagnosis...
  5. pmc Association of Mycobacterium avium subsp. paratuberculosis with multiple sclerosis in Sardinian patients
    Davide Cossu
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia e Virologia, Universita di Sassari, Sassari, Italy
    PLoS ONE 6:e18482. 2011
    ..Further studies will be required to confirm if MAP could be one of the triggers of MS, according to the molecular mimicry theory, in susceptible (and genetically at risk) individuals...
  6. pmc In vitro cytokine profiles and viability of different human cells treated with whole cell lysate of Mycobacterium avium subsp. paratuberculosis
    Pittu Sandhya Rani
    Pathogen Biology Laboratory, Department of Biotechnology, School of Life Sciences, University of Hyderabad, Hyderabad, India
    Gut Pathog 4:10. 2012
    ..We also found that MAP lysate induced cytotoxicity in PANC-1cells. Collectively, these results provide a much needed base-line data set of cytokines broadly signifying a MAP induced cellular response by human cells...
  7. pmc Gene expression profiling of Mycobacterium avium subsp. paratuberculosis in simulated multi-stress conditions and within THP-1 cells reveals a new kind of interactive intramacrophage behaviour
    Andrea Cossu
    Department of Biomedical Sciences, Division of Experimental and Clinical Microbiology, University of Sassari, Sassari, Italy
    BMC Microbiol 12:87. 2012
    ....
  8. pmc Sardinian Type 1 diabetes patients, Transthyretin and Mycobacterium avium subspecies paratuberculosis infection
    Speranza Masala
    Department of Biomedical Sciences, Division of Experimental and Clinical Microbiology, University of Sassari, Sassari, Italy
    Gut Pathog 4:24. 2012
    ..abstract:..
  9. pmc Interaction between Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium avium subspecies paratuberculosis with the enteric glia and microglial cells
    Sara Cannas
    Dipartimento di Scienze Biomediche Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Italy
    Gut Pathog 3:19. 2011
    ..abstract:..
  10. pmc Comparative genomics of Helicobacter pylori isolates recovered from ulcer disease patients in England
    Farhana Kauser
    Pathogen Evolution Group, Laboratory of Molecular and Cell Biology, Centre for DNA Fingerprinting and Diagnostics CDFD, Hyderabad, India
    BMC Microbiol 5:32. 2005
    ..Phylogenetic analysis was carried out based on various high-resolution genotyping techniques...
  11. pmc Ancestral European roots of Helicobacter pylori in India
    S Manjulata Devi
    Pathogen Evolution Group, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    BMC Genomics 8:184. 2007
    ..pylori. We tried to address these issues through mapping genetic origins of present day H. pylori in India and their genomic comparison with hundreds of isolates from different geographic regions...
  12. pmc Genomes of Helicobacter pylori from native Peruvians suggest admixture of ancestral and modern lineages and reveal a western type cag-pathogenicity island
    S Manjulata Devi
    Pathogen Evolution Group, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    BMC Genomics 7:191. 2006
    ..pylori of native Peruvians (of Amerindian ancestry) and their genomic comparison with isolates from Spain, and Japan...
  13. pmc Mycobacterium avium subspecies paratuberculosis is not associated with type-2 diabetes mellitus
    Valentina Rosu
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia clinica e sperimentale, viale San Pietro 43 b 07100 Sassari, Italy
    Ann Clin Microbiol Antimicrob 7:9. 2008
    ..paratuberculosis (MAP) shown a clear association of MAP with the presence of type 1 diabetes mellitus (T1DM)...
  14. pmc Antimicrobial activities of Eugenol and Cinnamaldehyde against the human gastric pathogen Helicobacter pylori
    Shaik Mahaboob Ali
    Department of Microbiology, Osmania University, Hyderabad 500 007, India
    Ann Clin Microbiol Antimicrob 4:20. 2005
    ..Eugenol and cinnamaldehyde that are commonly used in various food preparations are known to possess antimicrobial activity against a wide spectrum of bacteria...
  15. pmc Helicobacter pylori and gastroduodenal pathology: new threats of the old friend
    Niyaz Ahmed
    Pathogen Evolution Group, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    Ann Clin Microbiol Antimicrob 4:1. 2005
    ..The contribution of comparative genomics to our understanding of the genome organisation and diversity of H. pylori and its pathophysiological importance to human healthcare is exemplified in this review...
  16. pmc Mycobacterium avium subsp. paratuberculosis as a trigger of type-1 diabetes: destination Sardinia, or beyond?
    Pittu Sandhya Rani
    Pathogen Biology Laboratory, School of Life Sciences, University of Hyderabad, Hyderabad, India
    Gut Pathog 2:1. 2010
    ..Systematic mechanistic insights are needed to prove this link. Unfortunately, no easy animal model(s) or in-vitro systems are available to decipher the complex immunological network that is triggered in MAP infection leading to T1DM...
  17. ncbi request reprint Relationship between Crohn's disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Viale S Pietro 43 B, 07100 Sassari, Italy
    World J Gastroenterol 12:7161-4. 2006
    ....
  18. ncbi request reprint Mycobacterium avium subspecies paratuberculosis infects and multiplies in enteric glial cells
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Viale S Pietro 43 B, Sassari 07100, Italy
    World J Gastroenterol 13:5731-5. 2007
    ..To establish the role of enteric glial cells during infection with Mycobacterium avium subspecies paratuberculosis (MAP) in Crohn's disease...
  19. pmc Humoral immune responses of type 1 diabetes patients to Mycobacterium avium subsp. paratuberculosis lend support to the infectious trigger hypothesis
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Universita di Sassari, Viale San Pietro 43b, 07100 Sassari, Italy
    Clin Vaccine Immunol 15:320-6. 2008
    ..Finding evidence of M. avium subsp. paratuberculosis involvement in T1DM is perhaps a novel finding that might serve as a foundation stone in establishing an infectious etiology for T1DM...
  20. ncbi request reprint PER-1 type beta-lactamase production in Acinetobacter baumannii is related to cell adhesion
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, University of Sassari, Viale San Pietro 43b, 07100 Sassari, Italy
    Med Sci Monit 10:BR180-4. 2004
    ..We investigated the presence and the association of various virulence determinants in 20 Acinetobacter baumannii isolates, of which 13 were blaPER-1 positive...
  21. pmc "In vitro" activities of antimycobacterial agents against Mycobacterium avium subsp. paratuberculosis linked to Crohn's disease and paratuberculosis
    Stefania Zanetti
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Viale S, Pietro 43 B, 07100 Sassari, Italy
    Ann Clin Microbiol Antimicrob 5:27. 2006
  22. ncbi request reprint Immunogenicity and cytoadherence of recombinant heparin binding haemagglutinin (HBHA) of Mycobacterium avium subsp. paratuberculosis: functional promiscuity or a role in virulence?
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Sassari, Italy
    Vaccine 24:236-43. 2006
    ..Since M. tuberculosis HBHA was earlier shown to be involved in dissemination of the tubercle bacilli, the immunogenicity and cytoadherent nature of this MAP protein possibly suggests functional promiscuity...
  23. pmc Mycobacterium avium subsp. paratuberculosis, genetic susceptibility to Crohn's disease, and Sardinians: the way ahead
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Viale S Pietro 43 B, 07100 Sassari, Italy
    J Clin Microbiol 43:5275-7. 2005
    ..Our results show that more than 70 percent of people in Sardinia with Crohn's disease carry at least one of the susceptibility-associated NOD 2/CARD 15 alleles and were infected with Mycobacterium avium subspecies paratuberculosis...
  24. ncbi request reprint Immunization with DNA vaccines encoding different mycobacterial antigens elicits a Th1 type immune response in lambs and protects against Mycobacterium avium subspecies paratuberculosis infection
    L A Sechi
    Dipartimento di Scienze Biomediche, Sezione Microbiologia sperimentale e clinica, Facolta di Medicina, Viale S Pietro 43 B, 07100 Sassari, Italy
    Vaccine 24:229-35. 2006
    ..paratuberculosis by evaluating the expression level of INF-gamma and evaluating the presence of M. paratuberculosis and animal cell organ damage post-mortem...
  25. ncbi request reprint Detection and Isolation of Mycobacterium avium subspecies paratuberculosis from intestinal mucosal biopsies of patients with and without Crohn's disease in Sardinia
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Sassari, Italy
    Am J Gastroenterol 100:1529-36. 2005
    ..The present study was designed to determine what proportion of people in Sardinia attending for ileocolonoscopy with or without Crohn's disease were infected with this pathogen...
  26. ncbi request reprint Detection of virulence factors in a corneal isolate of Klebsiella pneumoniae
    Antonio Pinna
    Institute of Ophthalmology, University of Sassari, Sassari, Italy
    Ophthalmology 112:883-7. 2005
    ..To report on the microbiological findings of a Klebsiella pneumoniae strain isolated from a patient with keratitis...
  27. pmc Patients with pulmonary tuberculosis develop a strong humoral response against methylated heparin-binding hemagglutinin
    Stefania Zanetti
    Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy
    Clin Diagn Lab Immunol 12:1135-8. 2005
    ..Conversely, purified methylated HBHA was strongly recognized by sera obtained from TB patients compared to controls...
  28. ncbi request reprint Quinoxalin-2-ones. Part 5. Synthesis and antimicrobial evaluation of 3-alkyl-, 3-halomethyl- and 3-carboxyethylquinoxaline-2-ones variously substituted on the benzo-moiety
    Antonio Carta
    Dipartimento Farmaco Chimico Tossicologico, Via Muroni 23 A, 07100 Sassari, Italy
    Farmaco 58:1251-5. 2003
    ..Results of the screening showed that compounds 9b, 14b and 19b (MIC=62.5 microg/ml) and 10b (MIC=15.6 microg/ml) were the most active against Vibrio alginolyticus...
  29. ncbi request reprint Genome and transcriptome scale portrait of sigma factors in Mycobacterium avium subsp. paratuberculosis
    Leonardo A Sechi
    Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Viale S Pietro 43 B, 07100 Sassari, Italy
    Infect Genet Evol 7:424-32. 2007
    ..Thus, this first report on expression of MAP sigma factors opens the way to an extensive characterization of global gene regulation, as a key to understand strategies of survival and mechanisms of infections used by this organism...
  30. doi request reprint An outbreak of post-cataract surgery endophthalmitis caused by Pseudomonas aeruginosa
    Antonio Pinna
    Institute of Ophthalmology, University of Sassari, Sassari, Italy
    Ophthalmology 116:2321-6.e1-4. 2009
    ..The purpose of this study was to investigate an outbreak of post-cataract surgery P. aeruginosa endophthalmitis in India...
  31. ncbi request reprint In vitro efficacy of Linezolid on clinical strains of Mycobacterium tuberculosis and other mycobacteria
    Paola Molicotti
    Department of Biomedical Sciences, Institute of Microbiology, University of Sassari, Italy
    New Microbiol 29:275-80. 2006
    ..5 to 2 microg/ml. Linezolid can be used in combination with the standard antitubercular medications, or as an effective therapeutic alternative in infections caused by M. tuberculosis or by other species of non-tubercular mycobacteria...
  32. ncbi request reprint Heparin binding haemagglutin as potential diagnostic marker of Mycobacterium bovis
    Paola Molicotti
    Department of Biomedical Sciences, University of Sassari, Italy
    New Microbiol 31:423-7. 2008
    ..Our results indicated that HBHA is a potential candidate for the development of a serological assay for rapid diagnosis of cattle infected with M. bovis...
  33. doi request reprint Detection of virulence factors in Pseudomonas aeruginosa strains isolated from contact lens-associated corneal ulcers
    Antonio Pinna
    Institute of Ophthalmology, Section of Experimental and Clinical Microbiology, University of Sassari, Sassari, Italy
    Cornea 27:320-6. 2008
    ..The purpose of this study was to report on the microbiological findings of 8 P. aeruginosa strains isolated from contact lens-associated corneal ulcers...
  34. ncbi request reprint Aeromonas caviae keratitis associated with contact lens wear
    Antonio Pinna
    Institute of Ophthalmology, University of Sassari, Sassari, Italy
    Ophthalmology 111:348-51. 2004
    ..We report the first case of bilateral contact lens-related Aeromonas caviae keratitis associated with A. caviae contamination of the contact lens case. The presence of virulence factors produced by Aeromonas species was also investigated...
  35. pmc Mycobacterium avium subspecies paratuberculosis infection in cases of irritable bowel syndrome and comparison with Crohn's disease and Johne's disease: common neural and immune pathogenicities
    Antonio M Scanu
    Instituto di Clinica Chirurgica Generale, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Sassari, Italy
    J Clin Microbiol 45:3883-90. 2007
    ..paratuberculosis infection and the consumption of hand-made cheese. Mycobacterium avium subsp. paratuberculosis is a candidate pathogen in the causation of a proportion of cases of irritable bowel syndrome as well as in Crohn's disease...
  36. pmc Rapid identification of Mycobacterium tuberculosis Beijing genotypes on the basis of the mycobacterial interspersed repetitive unit locus 26 signature
    K Rajender Rao
    Pathogen Evolution Group, Laboratory of Molecular and Cell Biology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nacharam, Hyderabad, India
    J Clin Microbiol 44:274-7. 2006
    ..The test can also be adopted for direct application on clinical samples to save time on culturing bacilli for genotyping...
  37. ncbi request reprint Phages specific for mycobacterial lipoarabinomannan help serodiagnosis of tuberculosis
    Alessandra Bua
    Dipartimento di Scienze Biomediche, Universita di Sassari, Sassari, Italy
    New Microbiol 32:293-6. 2009
    ..Our results confirm that phage display technology might be useful to develop new tools for diagnosis of tuberculosis...
  38. pmc Genetic affinities within a large global collection of pathogenic Leptospira: implications for strain identification and molecular epidemiology
    Kishore Nalam
    Pathogen Biology Laboratory, Department of Biotechnology, School of Life Sciences, University of Hyderabad, Hyderabad, India
    PLoS ONE 5:e12637. 2010
    ....
  39. ncbi request reprint QuantiFERON TB Gold: a new method for latent tuberculosis infection
    Alessandra Bua
    Department of Biomedical Sciences, University of Sassari, Italy
    New Microbiol 30:477-80. 2007
    ..tuberculosis and its use alongside traditional diagnostic techniques may be an important instrument for controlling tuberculosis...
  40. pmc Isocitrate dehydrogenase of Helicobacter pylori potentially induces humoral immune response in subjects with peptic ulcer disease and gastritis
    M Abid Hussain
    Pathogen Evolution Laboratory, Centre for DNA Fingerprinting and Diagnostics CDFD, Hyderabad, India
    PLoS ONE 3:e1481. 2008
    ..We report immunogenic potentials of isocitrate dehydrogenase (ICD), an important house keeping protein of H. pylori...
  41. pmc The cag pathogenicity island of Helicobacter pylori is disrupted in the majority of patient isolates from different human populations
    Farhana Kauser
    Pathogen Evolution Group, Center for DNA Fingerprinting and Diagnostics, Hyderabad 500 076, India
    J Clin Microbiol 42:5302-8. 2004
    ..Analysis of the cag-PAI genotypes with a different biogeoclimatic history will contribute to our understanding of the pathogen-host interaction in health and disease...
  42. ncbi request reprint Prevalence and characterization of Enterococcus spp. isolated from Brazilian foods
    Bruna C Gomes
    Faculdade de Ciencias Farmaceuticas, Universidade de Sao Paulo, Av Prof Lineu Prestes 580, Bloco 13B, 05508 900 Sao Paulo, Brazil
    Food Microbiol 25:668-75. 2008
    ..faecium isolates with no virulence traits suggests their potential for biotechnological applications. In conclusion, our results showed that enterococci from Brazilian foods present important dualist aspects for food safety...
  43. doi request reprint Antimicrobial activity of Inula helenium L. essential oil against Gram-positive and Gram-negative bacteria and Candida spp
    Antonella Deriu
    Int J Antimicrob Agents 31:588-90. 2008
  44. pmc Molecular genotyping of a large, multicentric collection of tubercle bacilli indicates geographical partitioning of strain variation and has implications for global epidemiology of Mycobacterium tuberculosis
    Niyaz Ahmed
    Pathogen Evolution Group, Centre for DNA Fingerprinting and Diagnostics, Hyderabad 500 076, India
    J Clin Microbiol 42:3240-7. 2004
    ..The genotypic data reported here are additionally significant for genotype-phenotype correlations and for determining whether pathogen diversity is a reflection f the host population diversity...
  45. ncbi request reprint PCR-based detection of the Mycobacterium tuberculosis complex in urine of HIV-infected and uninfected pulmonary and extrapulmonary tuberculosis patients in Burkina Faso
    Gabriela Torrea
    Mycobacteriology Laboratory, Centre Muraz, Bobo Dioulasso, Burkina Faso
    J Med Microbiol 54:39-44. 2005
    ..This method is not appropriate for detection of new TB cases in the routine laboratory, but it can be useful for cases where the clinical and bacteriological diagnosis of TB is not conclusive...
  46. ncbi request reprint Mycobacterium tuberculosis molecular evolution in western Mediterranean Islands of Sicily and Sardinia
    Christophe Sola
    Unite de la Tuberculose et des Mycobacteries, Institut Pasteur de Guadeloupe, Morne Joliviere, BP 484, F97165 Pointe à Pitre, Guadeloupe, France
    Infect Genet Evol 5:145-56. 2005
    ..tuberculosis complex. The results obtained are paradigmatic of the complex interplay that exists between epidemic dynamics and evolutionary genetics of M. tuberculosis...
  47. pmc Analysis of genomic downsizing on the basis of region-of-difference polymorphism profiling of Mycobacterium tuberculosis patient isolates reveals geographic partitioning
    K Rajender Rao
    Centre for DNA Fingerprinting and Diagnostics, Hyderabad 500 076, India
    J Clin Microbiol 43:5978-82. 2005
    ..This study highlights that the RDs in M. tuberculosis genomes are geographically distributed and specific and may possibly be associated with virulence spectrum...
  48. pmc Rapid diagnosis of mycobacterial infections and quantitation of Mycobacterium tuberculosis load by two real-time calibrated PCR assays
    Francesco Broccolo
    Unit of Human Virology, San Raffaele Scientific Institute, Milan, Italy
    J Clin Microbiol 41:4565-72. 2003
    ..Therefore, these assays represent a fully controlled high-throughput system for the evaluation of mycobacterial burden in clinical specimens...
  49. ncbi request reprint In vitro adherence of Staphylococcus epidermidis, Serratia marcescens, and Pseudomonas aeruginosa to AcrySof intraocular lenses
    Antonio Pinna
    J Cataract Refract Surg 31:2430-1. 2005
  50. ncbi request reprint Antigenic profiles of recombinant proteins from Mycobacterium avium subsp. paratuberculosis in sheep with Johne's disease
    John P Bannantine
    National Animal Disease Center, USDA Agricultural Research Service, Ames, IA 50010, USA
    Vet Immunol Immunopathol 122:116-25. 2008
    ..This study evaluated multiple M. avium subsp. paratuberculosis recombinant proteins in an ELISA-based format for sheep...
  51. ncbi request reprint Mycobacterium avium subspecies paratuberculosis bacteremia in type 1 diabetes mellitus: an infectious trigger?
    Leonardo A Sechi
    Clin Infect Dis 46:148-9. 2008
  52. ncbi request reprint Insulin sensitivity in patients with primary aldosteronism: a follow-up study
    Cristiana Catena
    Clinica Medica, University of Udine, Piazzale S Maria della Misericordia, 1, 33100 Udine, Italy
    J Clin Endocrinol Metab 91:3457-63. 2006
    ....
  53. ncbi request reprint Regression of microalbuminuria in type 1 diabetes
    Cristiana Catena
    N Engl J Med 349:906-8; author reply 906-8. 2003
  54. ncbi request reprint Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment
    Marileda Novello
    Division of Internal Medicine, Department of Experimental and Clinical Pathology and Medicine, University of Udine, Udine, Italy
    J Hypertens 25:1443-50. 2007
    ..The nature of this association could be related to hypokalemia and/or hypertension and has never been evaluated in prospective studies...
  55. ncbi request reprint Increased serum resistin in nonalcoholic fatty liver disease is related to liver disease severity and not to insulin resistance
    Claudio Pagano
    Department of Medical and Surgical Sciences, University of Padova, Via Ospedale 105, 35100 Padova, Italy
    J Clin Endocrinol Metab 91:1081-6. 2006
    ..The recently discovered hormone resistin is linked to the development of insulin resistance, but direct evidence of resistin levels in humans with nonalcoholic fatty liver disease (NAFLD) is lacking...
  56. ncbi request reprint AmpliBASE MT: a Mycobacterium tuberculosis diversity knowledgebase
    Ahmed A Majeed
    Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad 500076, India
    Bioinformatics 20:989-92. 2004
    ....
  57. ncbi request reprint Mycobacterium marinum, a further infectious agent associated with sarcoidosis: the polyetiology hypothesis
    Oswald Moling
    Division of Infectious Diseases, Ospedale Generale, Bolzano, Italy
    Scand J Infect Dis 38:148-52. 2006
    ..After this, Mycobacterium marinum-DNA was identified in the stored lung biopsies by the PCR-RFLP of the hsp65 gene...