Genomes and Genes
Affiliation: University of Rome La Sapienza
- A distinctive 'microbial signature' in celiac pediatric patientsSerena Schippa
Department of Public Health Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, Rome, 00185, Italy
BMC Microbiol 10:175. 2010..Total DNA was extracted from duodenal biopsies and amplification products of 16S ribosomal DNA were compared by temporal temperature gradient gel electrophoresis (TTGE). TTGE profiles were analyzed by statistical multivariate analysis...
- Microevolution in fimH gene of mucosa-associated Escherichia coli strains isolated from pediatric patients with inflammatory bowel diseaseValerio Iebba
Microbiology Unit, Department of Public Health Sciences, Sapienza University of Rome, Rome, Italy
Infect Immun 80:1408-17. 2012..coli B2 phylogroup. In conclusion, we found some FimH variants that seem to be more involved than others in the evolution of IBD pathogenesis...
- A potential role of Escherichia coli pathobionts in the pathogenesis of pediatric inflammatory bowel diseaseSerena Schippa
Department of Public Health and Infectious Diseases, Sapienza University, Microbiology Section, Piazzale Aldo Moro, 5 00185, Rome, Italy
Can J Microbiol 58:426-32. 2012..It could be argued that the 11 selected strains could be a branch of an E. coli subpopulation (pathobionts), that could take advantage in an inflamed context because of a suitable genomic and (or) genetic backdrop...
- Cystic fibrosis transmembrane conductance regulator (CFTR) allelic variants relate to shifts in faecal microbiota of cystic fibrosis patientsSerena Schippa
Public Health and Infectious Diseases Department, Microbiology Unit, Sapienza University of Rome, Rome, Italy
PLoS ONE 8:e61176. 2013..Intestinal manifestations are underestimated in CF, leading to ileum meconium at birth, or small bowel bacterial overgrowth in adult age...
- Higher prevalence and abundance of Bdellovibrio bacteriovorus in the human gut of healthy subjectsValerio Iebba
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy
PLoS ONE 8:e61608. 2013..It was found in terrestrial/aquatic ecosystems, and in animal intestines, postulating its presence also in the human gut...
- Dominant genotypes in mucosa-associated Escherichia coli strains from pediatric patients with inflammatory bowel diseaseSerena Schippa
Department of Public Health Sciences, University of Rome La Sapienza, Rome, Italy
Inflamm Bowel Dis 15:661-72. 2009..The aim of this study was to characterize E. coli strains from the intestinal mucosa of pediatric IBD patients to investigate whether a particular subset of strains could be associated with the disease...
- Achromobacter xylosoxidans genomic characterization and correlation of randomly amplified polymorphic DNA profiles with relevant clinical features [corrected] of cystic fibrosis patientsAnnarita Magni
Department of Public Health Sciences, Sapienza University, Piazzale Aldo Moro 5, 00185 Rome, Italy
J Clin Microbiol 48:1035-9. 2010..xylosoxidans. These findings seem to imply that the lung habitats found in CF patients are capable of shaping and selecting the colonizing bacterial flora, as seems to be the case for the A. xylosoxidans strains studied...
- The microbiota in inflammatory bowel disease in different age groupsSalvatore Cucchiara
Pediatric Gastroenterology and Liver Unit, Department of Pediatrics, Sapienza University of Rome, IT 00161 Rome, Italy
Dig Dis 27:252-8. 2009..On the other hand, existing differences in gut microbial community between distinct classes of age make sense of an increasing research in microbial shifts in IBD...