Patrizia Scapini

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. ncbi B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice
    Patrizia Scapini
    Department of Laboratory Medicine and Microbiology Immunology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 108:E823-32. 2011
  2. ncbi Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice
    Patrizia Scapini
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    J Exp Med 207:1757-73. 2010
  3. ncbi Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis
    Marco A Cassatella
    Department of Pathology, Division of General Pathology, University of Verona, Verona, Italy
    J Immunol 178:7325-33. 2007
  4. ncbi Deletion of Syk in neutrophils prevents immune complex arthritis
    Emily R Elliott
    Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA
    J Immunol 187:4319-30. 2011
  5. ncbi Multiple roles of Lyn kinase in myeloid cell signaling and function
    Patrizia Scapini
    Department of Laboratory Medicine, University of California, San Francisco, CA 94143 0451, USA
    Immunol Rev 228:23-40. 2009
  6. ncbi The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity
    Rita M Tavares
    Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Immunity 33:181-91. 2010

Collaborators

Detail Information

Publications6

  1. ncbi B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice
    Patrizia Scapini
    Department of Laboratory Medicine and Microbiology Immunology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 108:E823-32. 2011
    ....
  2. ncbi Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice
    Patrizia Scapini
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    J Exp Med 207:1757-73. 2010
    ..Our findings uncover an important pathological role of BAFF in autoimmune disorders...
  3. ncbi Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis
    Marco A Cassatella
    Department of Pathology, Division of General Pathology, University of Verona, Verona, Italy
    J Immunol 178:7325-33. 2007
    ....
  4. ncbi Deletion of Syk in neutrophils prevents immune complex arthritis
    Emily R Elliott
    Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA
    J Immunol 187:4319-30. 2011
    ..Basophil-deficient mice also responded normally to K/BxN serum transfer. These results demonstrate that Syk-dependent signaling in neutrophils alone is critically required for arthritis development in the serum transfer model...
  5. ncbi Multiple roles of Lyn kinase in myeloid cell signaling and function
    Patrizia Scapini
    Department of Laboratory Medicine, University of California, San Francisco, CA 94143 0451, USA
    Immunol Rev 228:23-40. 2009
    ..In this review, we discuss the current knowledge of the duplicitous nature of Lyn in the modulation of myeloid cell signaling and function...
  6. ncbi The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity
    Rita M Tavares
    Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Immunity 33:181-91. 2010
    ..These findings show that A20 can restrict B cell survival, whereas A20 protects other cells from TNF-induced cell death. Our studies demonstrate how reduced A20 expression predisposes to autoimmunity...