Research Topics
| Francesco SavinoSummaryAffiliation: University of Turin Country: Italy Publications
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Detail Information
Publications
Focus on infantile colicFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, Piazza Polonia 94, 10126 Turin, Italy
Acta Paediatr 96:1259-64. 2007..However, further research and guidelines are still needed...- Cimetropium bromide in the treatment of crisis in infantile colicFrancesco Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Universita di Torino, Ospedale Infantile Regina Margherita, Torino, Italy
J Pediatr Gastroenterol Nutr 34:417-9. 2002..The aim of this randomized, double-blind, placebo-controlled clinical trial was to investigate the effectiveness and side effects of cimetropium bromide in the treatment of infants with colic crisis... - [Advances on the effects of the compounds of a phytotherapic agent (COLIMIL) on upper gastrointestinal transit in mice]F Savino
Dipartimento di Farmacologia Sperimentale, Universita Federico II, Napoli, Italy
Minerva Pediatr 60:285-90. 2008.... 
Efficacy and tolerability of peg-only laxative on faecal impaction and chronic constipation in children. A controlled double blind randomized study vs a standard peg-electrolyte laxativeFrancesco Savino
Department of Pediatrics 1, Regina Margherita Children s Hospital, University of Turin, Azienda Ospedaliera Città della Salute e della Scienza della Città di Torino, Turin, Italy
BMC Pediatr 12:178. 2012....
Adiponectin in breast milk: relation to serum adiponectin concentration in lactating mothers and their infantsF Savino
Department of Paediatrics, University of Turin, Regina Margherita Children s Hospital, Turin, Italy
Acta Paediatr 101:1058-62. 2012....- Resistin and leptin in breast milk and infants in early lifeFrancesco Savino
Department of Paediatrics, University of Turin, Regina Margherita Children s Hospital, Italy
Early Hum Dev 88:779-82. 2012..The role of adipokines in early life is considered an emerging topic issue in nutritional researches... - Ghrelin and feeding behaviour in preterm infantsFrancesco Savino
Department of Paediatrics, Regina Margherita Children s Hospital, University of Turin, Italy
Early Hum Dev 88:S51-5. 2012..However, more research is required to better define ghrelin's role in breast milk and on feeding behaviour... - Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized studyFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, Piazza Polonia, 94 10126 Turin, Italy
Pediatrics 119:e124-30. 2007..The goal was to test the hypothesis that oral administration of Lactobacillus reuteri in a prospective randomized study would improve symptoms of infantile colic... - Ghrelin, motilin, insulin concentration in healthy infants in the first months of life: relation to fasting time and anthropometryF Savino
Department of Paediatrics, Regina Margherita Hospital, Turin University, Italy
Clin Endocrinol (Oxf) 65:158-62. 2006.... - Methemoglobinemia caused by the ingestion of courgette soup given in order to resolve constipation in two formula-fed infantsFrancesco Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Universita di Torino, Azienda Ospedaliera OIRM S Anna, Torino, Italy
Ann Nutr Metab 50:368-71. 2006..g., courgette, spinach, beets and green beans) to resolve constipation since, particularly in the first months of life, they may cause severe methemoglobinemia... - Ghrelin and motilin concentration in colicky infantsFrancesco Savino
Department of Paediatrics, Regina Margherita Hospital, Turin University, Turin, Italy
Acta Paediatr 95:738-41. 2006..To evaluate serum ghrelin and motilin concentration in infants with infantile colic... - Reduction of crying episodes owing to infantile colic: A randomized controlled study on the efficacy of a new infant formulaF Savino
Department of Paediatrics, University of Turin, Turin, Italy
Eur J Clin Nutr 60:1304-10. 2006..The aim of this study was to evaluate the efficacy on crying episodes owing to infantile colic of a new infant formula containing partially hydrolysed whey proteins, prebiotic oligosaccharides (OS), with a high beta-palmitic acid content... - Maternal BMI and serum leptin concentration of infants in the first year of lifeFrancesco Savino
Department of Paediatrics, Regina Margherita Children s Hospital, University of Turin, Turin, Italy
Acta Paediatr 95:414-8. 2006..To evaluate the relationship between serum leptin concentration in infants and infant and maternal BMI... - Adiponectin: an intriguing hormone for paediatriciansF Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, Turin, Italy
Acta Paediatr 97:701-5. 2008..CONCLUSION: This review demonstrates an emerging interest of paediatric research on adiponectin. A better understanding of adiponectin's bioactivity might clarify whether breast milk indeed prevents childhood obesity... - Can hormones contained in mothers' milk account for the beneficial effect of breast-feeding on obesity in children?Francesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, 10126 Turin, Italy
Clin Endocrinol (Oxf) 71:757-65. 2009..In this review, we examine the data related to hormones contained in mothers' milk and their potential protective effect on subsequent obesity and metabolic-related disorders... - Evaluation of leptin in breast milk, lactating mothers and their infantsF Savino
Department of Paediatrics, University of Turin, Regina Margherita Children s Hospital, Torino, Italy
Eur J Clin Nutr 64:972-7. 2010.... - Adipokines in breast milk and preterm infantsFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, Piazza Polonia 94, Turin, Italy
Early Hum Dev 86:77-80. 2010..Future research is necessary to clarify the role of hormones present in breast milk for identifying potential short- and long-term effects of breastfeeding on the health of children born prematurely... - Update on breast milk hormones: leptin, ghrelin and adiponectinFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, Italy
Clin Nutr 27:42-7. 2008..In this review, we present a synopsis of previous and recent studies focusing on hormones in breast milk. It appears that promoting breastfeeding is an important factor in this process... - Serum ghrelin concentration, fasting time and feeding in infantsFrancesco Savino
Department of Pediatrics, Ospedale Infantile Regina Margherita, University of Turin, Italy
J Pediatr Endocrinol Metab 20:1027-33. 2007..Data on hormonal feeding control in infants in the first months of life according to the kind of feeding are scanty... - Looking for a relation between serum leptin concentration and body composition parameters in healthy term infants in the first 6 months of lifeFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, Italy
J Pediatr Gastroenterol Nutr 46:348-51. 2008..002), and was not correlated with body composition parameters. This study indicates that there is a relation between leptin and infant body composition in the first months of life, although the link needs to be explored further... - High faecal calprotectin levels in healthy, exclusively breast-fed infantsFrancesco Savino
Department of Paediatrics, Regina Margherita Children s Hospital, University of Turin, Turin, Italy
Neonatology 97:299-304. 2010..High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial... - Molecular identification of coliform bacteria from colicky breastfed infantsF Savino
Department of Pediatrics, Regina Margherita Children Hospital, University of Turin, Torino, Italy
Acta Paediatr 98:1582-8. 2009..To determine the presence of intestinal coliform bacteria in colicky vs healthy infants... - Serum ghrelin concentration and weight gain in healthy term infants in the first year of lifeF Savino
Department of Pediatrics, Ospedale Infantile Regina Margherita University of Turin, Torino, Italy
J Pediatr Gastroenterol Nutr 41:653-9. 2005..There are few studies on this hormone in healthy infants during the first year of life. The aim of this study was to examine the correlations between ghrelin and weight gain in healthy term infants in the first year of life... - A prospective 10-year study on children who had severe infantile colicFrancesco Savino
Department of Paediatrics, University of Turin, Turin, Italy
Acta Paediatr Suppl 94:129-32. 2005..To evaluate the association between infantile colic and gastrointestinal, allergic and psychological disorders in childhood... - Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trialFrancesco Savino
Department of Pediatrics, Regina Margherita Children Hospital, University of Turin, Piazza Polonia, 94 10126 Turin, Italy
Pediatrics 126:e526-33. 2010..To test the efficacy of Lactobacillus reuteri on infantile colic and to evaluate its relationship to the gut microbiota... - Assay of ghrelin concentration in infant formulas and breast milkFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, Piazza Polonia 94 10126, Turin, Italy
World J Gastroenterol 17:1971-5. 2011..To test if total ghrelin is present in infant formulas... - Antagonistic effect of Lactobacillus strains against gas-producing coliforms isolated from colicky infantsFrancesco Savino
Department of Pediatrics, Regina Margherita Children Hospital, Torino, Italy
BMC Microbiol 11:157. 2011..This study was performed to evaluate the interaction between Lactobacillus spp. strains and gas-forming coliforms isolated from stools of colicky infants... - The Biagram vector: a graphical relation between reactance and phase angle measured by bioelectrical analysis in infantsF Savino
Department of Pediatrics, University of Turin, Regina Margherita Children Hospital, Torino, Italy
Ann Nutr Metab 48:84-9. 2004.... - Gastric emptying in infants: epigastric impedance versus scintigraphyF Savino
Department of Paediatrics, University of Turin, Regina Margherita Children Hospital, Turin, Italy
Acta Paediatr 93:608-12. 2004..To compare epigastric impedance versus scintigraphy in monitoring the gastric emptying of the same adapted milk formula in infants... - Intestinal microflora in breastfed colicky and non-colicky infantsF Savino
Department of Paediatrics, University of Turin, Turin, Italy
Acta Paediatr 93:825-9. 2004..Actually, in the literature, only few data have been collected about this topic. In this study, we evaluated intestinal microflora in breastfed colicky and non-colicky infants... - Fulminant hepatitis after 10 days of acetaminophen treatment at recommended dosage in an infantFrancesco Savino
Department of Paediatrics, Ospedale Infantile Regina Margherita, Turin, Italy
Pediatrics 127:e494-7. 2011..Health care providers should be aware that multiple doses of acetaminophen in infants may lead to acute hepatic failure. N-acetylcysteine therapy should be initiated in cases of drug-induced acute liver failure... - Bone mineral status in breast-fed infants: influence of vitamin D supplementationF Savino
Department of Paediatrics, Regina Margherita Children s Hospital, University of Turin, Turin, Italy
Eur J Clin Nutr 65:335-9. 2011..To assess bone status using quantitative ultrasound (QUS) applied to the second metacarpus and to evaluate the influence of vitamin D supplementation on bone mineralization in exclusively breast-fed infants... - Breast-fed infants have higher leptin values than formula-fed infants in the first four months of lifeF Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Ospedale Infantile Regina Margherita, Universita di Torino, Italy
J Pediatr Endocrinol Metab 17:1527-32. 2004..Leptin is a hormone present in breast milk, which regulates food intake and energy metabolism... - Advances in the management of digestive problems during the first months of lifeFrancesco Savino
Department of Paediatrics, Ospedale Infantile Regina Margherita, University of Turin, Turin, Italy
Acta Paediatr Suppl 94:120-4. 2005..CONCLUSION: A prebiotic mixture of galacto-/fructo-oligosaccharides with a high beta-palmitic acid content may reduce digestive problems and improve intestinal tolerance in infants during the first months of life... - Z-score of weight for age of infants with atopic dermatitis and cow's milk allergy fed with a rice-hydrolysate formula during the first two years of lifeFrancesco Savino
Ospedale Infantile Regina Margherita, Department of Paediatrics, University of Turin, Turin, Italy
Acta Paediatr Suppl 94:115-9. 2005..Aim: To evaluate the growth of infants fed with a rice-based hydrolysate formula, compared to those infants fed with a soy formula or an extensively hydrolysed casein formula, in the first 2 y of life... - New treatments for infant colicFrancesco Savino
Department of Pediatrics, Regina Margherita Children Hospital, University of Turin, Turin, Italy
Curr Opin Pediatr 22:791-7. 2010..Despite 40 years of research, its pathogenesis is incompletely understood and treatment remains an open issue. This review will describe recent studies that have examined different kinds of interventions... - Ghrelin, leptin and IGF-I levels in breast-fed and formula-fed infants in the first years of lifeFrancesco Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Ospedale Infantile Regina Margherita, Universita di Torino, Torino, Italy
Acta Paediatr 94:531-7. 2005..To establish ghrelin, leptin and IGF-I serum levels in breastfed (BF) and formula-fed (FF) infants during the first period of life... - A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infantsFrancesco Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza Università di Torino, Ospedale Infantile Regina Margherita, Azienda Ospedaliera OIRM S Anna, Piazza Polonia, 94, 10126 Torino, Italy
Phytother Res 19:335-40. 2005.... - Relationships between IGF-I and weight Z score, BMI, tricipital skin-fold thickness, type of feeding in healthy infants in the first 5 months of lifeF Savino
Department of Paediatrics, University of Turin, Regina Margherita Hospital, Turin, Italy
Ann Nutr Metab 49:83-7. 2005.... - Faecal microbiota in breast-fed infants after antibiotic therapyF Savino
Department of Paediatrics, Ospedale Infantile Regina Margherita, Turin, Italy
Acta Paediatr 100:75-8. 2011..To evaluate modifications of gut microbiota after antibiotic therapy in breast-fed infants... - Bacterial counts of intestinal Lactobacillus species in infants with colicF Savino
Department of Paediatrics, University of Turin, Turin, Italy
Pediatr Allergy Immunol 16:72-5. 2005..Further studies are required to understand how the observed differences may be involved in the pathogenesis of this common disorder... - Bioelectrical impedance vector distribution in the first year of lifeFrancesco Savino
Department of Pediatrics, University of Turin, Regina Margherita Children Hospital, Piazza Polonia, 94 10126 Turin, Italy
Nutrition 19:492-6. 2003..We assessed the bioelectrical impedance vector distribution in a sample of healthy infants in the first year of life, which is not available in literature... - [Breast milk: biological constituents for health and well-being in infancy]Francesco Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Ospedale Infantile Regina Margherita, Torino
Recenti Prog Med 97:519-27. 2006..Anyway we have to remember that breastfeeding require a supplementation of vitamin D and K for some months and a correct weaning program is needed from the 5th-6th months of life to prevent iron deficiency... - Combined esophageal intraluminal impedance, pH and skin conductance monitoring to detect discomfort in GERD infantsFrancesco Cresi
Department of Pediatrics, University of Turin, S Anna Regina Margherita Children s Hospital, Turin, Italy
PLoS ONE 7:e43476. 2012..Our results may raise concerns about the over-prescription use of antacid drugs in the management of gastroesophageal reflux symptoms in infancy... - Blue baby syndromeFrancesco Savino
Dipartimento di Scienze Pediatriche e dell' Adolescenza, , Ospedale Infantile Regina Margherita, Azienda Ospedaliera OIRM S.ANNA, Italy
J Pediatr Gastroenterol Nutr 34:563, 573. 2002 - Multiple bone fractures in an 8-year-old child with cow's milk allergy and inappropriate calcium supplementationGiovanna Monti
Food Allergy Service, Department of Pediatric and Adolescence Science, Regina Margherita Children s Hospital, Turin, Italy
Ann Nutr Metab 51:228-31. 2007..This clinical report suggests that both vitamin D and calcium supplementation are necessary when a cow's milk protein-free diet is prescribed, even when a hypo- or non-allergenic formula is provided... - Infant nutritional recommendations from pediatricians. Epidemiologic survey of feeding recommendations for the first year of life in PiedmontF Savino
Department of Pediatric and Adolescence Sciences, University of Turin, Regina Margherita Children, Hospital, Turin, Italy
Minerva Pediatr 56:73-82. 2004..2 months. Cow's milk was introduced at 9 months. CONCLUSION: Paediatricians give indications about the introduction of solid foods according to scientific guidelines, with the exception of cow's milk which is introduced too early... - Breast milk hormones and regulation of glucose homeostasisFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, 10126 Turin, Italy
Int J Pediatr 2011:803985. 2011..This paper focuses on hormones present in breast milk and their role in glucose homeostasis... - Diarrheagenic Escherichia coli in acute gastroenteritis in infants in North-West ItalyGabriella Amisano
Department of Public Health and Microbiology, University of Turin, Italy
New Microbiol 34:45-51. 2011..Abbreviations: CDEC, detaching E. coli; DAEC, diffusely adherent E. coli; EAggEC, enteroaggregative E. coli; EHEC, enterohaemorrhagic E. coli; EIEC, enteroinvasive E. coli; EPEC, enteropathogenic E. coli; ETEC, enterotoxigenic E. coli... - "Minor" feeding problems during the first months of life: effect of a partially hydrolysed milk formula containing fructo- and galacto-oligosaccharidesF Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Universita di Torino, Ospedale Infantile Regina Margherita, Turin, Italy
Acta Paediatr Suppl 91:86-90. 2003..The aim of this prospective study was to describe the effects of such a formula in infants with minor gastrointestinal disorders... - Dog bites in children less than fourteen years old in TurinF Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Ospedale Infantile Regina Margherita, Azienda Ospedaliera OIRM S Anna, Universita degli Studi, Turin, Italy
Minerva Pediatr 54:237-42. 2002..The purpose of this study was to describe the epidemiology of injuries caused by dog bites treated in the emergency department of OIRM from January 1, 1997 to December 31, 2000... - Leptin levels in breast-fed and formula-fed infantsF Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Universita di Torino, Ospedale Regina Margherita, Italy
Acta Paediatr 91:897-902. 2002..The aim of this study was to evaluate whether diet and gender affect plasma leptin concentration in breastfed and formula-fed infants during the first months of life... - [Food intakes in breast-feeding mothers]F Savino
Dipartimento di Scienze Pediatriche e dell Adolescenza, Ospedale Infantile Regina Margherita, Azienda Ospedaliera OIRM S Anna, Universita degli Studi, Turin, Italy
Minerva Pediatr 53:177-82. 2001..We have also compared food intake of not breast feeding mothers with the LARN, and analyzed the differences between these groups of mothers... - Bioimpedance vector analysis in breastfed and formula-fed infants in the first six months of lifeF Savino
Department of Pediatrics, University of Turin, Italy
Adv Exp Med Biol 554:501-4. 2004 - Relationship between gastro-oesophageal reflux and gastric activity in newborns assessed by combined intraluminal impedance, pH metry and epigastric impedanceF Cresi
Neonatal Care Unit, Regina Margherita Children s Hospital, University of Turin, Turin, Italy
Neurogastroenterol Motil 18:361-8. 2006..05). Simultaneous MII, pH and EGI monitoring provided new information on the relationship between refluxes and gastric activity. Data suggest that gastric emptying patterns influence the frequency, level and pH of reflux episodes... - Breast milk hormones and their protective effect on obesityFrancesco Savino
Department of Pediatrics, Regina Margherita Children s Hospital, University of Turin, 10126 Turin, Italy
Int J Pediatr Endocrinol 2009:327505. 2009..Here we examine the data related to hormones contained in mother's milk and their potential protective effect on subsequent obesity... - Dietary modifications versus dicyclomine hydrochloride in the treatment of severe infantile colicsR Oggero
Institute of Pediatrics, University Hospital, Turin, Italy
Acta Paediatr 83:222-5. 1994..4% of cases. Pharmacological treatment provided an improvement in 53.3% of cases. The difference was significant (p < 0.01)... - Risk factors for severe pediatric food anaphylaxis in ItalyMauro Calvani
Department of Pediatrics, San Camillo de Lellis Hospital, Rome, Italy
Pediatr Allergy Immunol 22:813-9. 2011..Little is known about the cause of food-induced anaphylaxis in children or about the factors that might affect its clinical severity... - Effects of the herbal formulation ColiMil on upper gastrointestinal transit in mice in vivoRaffaele Capasso
Department of Experimental Pharmacology, University of Naples Federico II, 80131 Naples Italy
Phytother Res 21:999-1101. 2007..These experimental data may be important to better understand the observation that the herbal formulation ColiMil improves colic in breastfed infants... - Considerations and approaches in determining the protein and energy composition of preterm infant formulasSilvia Fanaro
Neonatal Intensive Care Unit, Department of Clinical and Experimental Medicine, University of Ferrara, Italy
Acta Paediatr Suppl 94:57-63. 2005..As a consequence there is a need of at least two milk formulas for different preterm infants: one for LBW and VLBW infants, the other for preterm infants weighing >1500 g... - Overprescription of antireflux medications for infants with regurgitationFrancesco Savino
Pediatrics 121:1070; author reply 1070-1. 2008