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..In addition to other factors that could impair the efficiency of the immune system in ketotic ruminants, the reduced bactericidal activity may contribute to the higher occurrence of infectious disease in these animals. ..
Sartorelli P, Panelli S, Comazzi S, Paltrinieri S. Isolation stress in sheep: effects on neutrophil gene expression of CD18, IL8 and C5a receptors. Vet Res Commun. 2003;27 Suppl 1:351-3 pubmed