Iacopo Sardi

Summary

Affiliation: University of Florence
Country: Italy

Publications

  1. ncbi request reprint Loss of heterozygosity and p53 polymorphism Pro72Arg in a young patient with medulloblastoma
    Iacopo Sardi
    Unita di Oncoematologia, Ospedale Pediatrico A Meyer, I 50132 Florence, Italy
    Oncol Rep 10:773-5. 2003
  2. ncbi request reprint Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma
    Iacopo Sardi
    Neuro surgery Units, Department of Neurosurgery, University of Florence Medical School, The A Meyer Children s Hospital, Florence 50132, Italy
    Oncol Rep 19:1219-23. 2008
  3. pmc Case report: long-term survival of an infant syndromic patient affected by atypical teratoid-rhabdoid tumor
    Piergiorgio Modena
    Unit of Experimental Oncology 1, Centro di Riferimento Oncologico, Aviano, 33081, Italy
    BMC Cancer 13:100. 2013
  4. ncbi request reprint Successful treatment with a low-dose cisplatin--etoposide regimen for patients with diencephalic syndrome
    Iacopo Sardi
    Department of Pediatric Hematology Oncology, A O U Meyer Children s Hospital, viale G Pieraccini 24, 50139, Florence, Italy
    J Neurooncol 109:375-83. 2012
  5. doi request reprint Monotherapy with thalidomide for treatment of spinal cord hemangioblastomas in a patient with von Hippel-Lindau disease
    Iacopo Sardi
    Department of Pediatric Hematology Oncology, A U O Anna Meyer Children s Hospital, Florence, Italy
    Pediatr Blood Cancer 53:464-7. 2009
  6. ncbi request reprint Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors
    Iacopo Sardi
    Department of Pediatric Hematology Oncology, University of Florence, A O U Meyer Children s Hospital, 50139 Florence, Italy
    Oncol Rep 22:773-9. 2009
  7. doi request reprint Intracerebral atypical presentation of echinococcosis in a child
    Iacopo Sardi
    Division of Neurosurgery, A Meyer Children s Hospital, University of Florence, Florence, Italy
    Pediatr Neurosurg 44:350-2. 2008
  8. ncbi request reprint Emerging treatments and gene expression profiling in high-risk medulloblastoma
    Iacopo Sardi
    Department of Pediatrics, Onco hematology and Neuro surgery Units, University of Florence Medical School, A Meyer Children s Hospital, Florence, Italy
    Paediatr Drugs 9:81-96. 2007
  9. doi request reprint Detection of doxorubicin hydrochloride accumulation in the rat brain after morphine treatment by mass spectrometry
    Iacopo Sardi
    Department of Onco Hematology and Neuro Surgery Units, A Meyer Children s Hospital, viale G Pieraccini 24, 50139 Florence, Italy
    Cancer Chemother Pharmacol 67:1333-40. 2011
  10. doi request reprint Glioneuronal tumor with neuropil-like islands: clinical, morphologic, immunohistochemical, and molecular features of three pediatric cases
    Anna Maria Buccoliero
    Pathology Unit, Anna Meyer Children s Hospital, Florence, Italy
    Pediatr Dev Pathol 15:352-60. 2012

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Loss of heterozygosity and p53 polymorphism Pro72Arg in a young patient with medulloblastoma
    Iacopo Sardi
    Unita di Oncoematologia, Ospedale Pediatrico A Meyer, I 50132 Florence, Italy
    Oncol Rep 10:773-5. 2003
    ..We identified the presence of LOH at 17p13 and Pro72Arg polymorphism in tumor DNA. These molecular findings helped us better characterize this undifferentiated tumor and led to a more aggressive therapy...
  2. ncbi request reprint Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma
    Iacopo Sardi
    Neuro surgery Units, Department of Neurosurgery, University of Florence Medical School, The A Meyer Children s Hospital, Florence 50132, Italy
    Oncol Rep 19:1219-23. 2008
    ....
  3. pmc Case report: long-term survival of an infant syndromic patient affected by atypical teratoid-rhabdoid tumor
    Piergiorgio Modena
    Unit of Experimental Oncology 1, Centro di Riferimento Oncologico, Aviano, 33081, Italy
    BMC Cancer 13:100. 2013
    ..A consistent fraction of cases carries de-novo SMARCB1/INI1 constitutional mutations in the setting of the "rhabdoid tumor predisposition syndrome" and the outcome is worst in infant syndromic ATRT patients...
  4. ncbi request reprint Successful treatment with a low-dose cisplatin--etoposide regimen for patients with diencephalic syndrome
    Iacopo Sardi
    Department of Pediatric Hematology Oncology, A O U Meyer Children s Hospital, viale G Pieraccini 24, 50139, Florence, Italy
    J Neurooncol 109:375-83. 2012
    ..A low-dose cisplatin-etoposide regimen is highly effective regarding tumor response and treatment of DS symptoms/cachexia without causing significant side-effects...
  5. doi request reprint Monotherapy with thalidomide for treatment of spinal cord hemangioblastomas in a patient with von Hippel-Lindau disease
    Iacopo Sardi
    Department of Pediatric Hematology Oncology, A U O Anna Meyer Children s Hospital, Florence, Italy
    Pediatr Blood Cancer 53:464-7. 2009
    ..The antiangiogenic effect of thalidomide may be associated with the control of progressive hemangioblastoma...
  6. ncbi request reprint Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors
    Iacopo Sardi
    Department of Pediatric Hematology Oncology, University of Florence, A O U Meyer Children s Hospital, 50139 Florence, Italy
    Oncol Rep 22:773-9. 2009
    ..The heterogeneous PFS in our patients treated with second line TMZ, indicates that MGMT expression alone is insufficient to predict the response to TMZ, presumably because of the DNA repair mechanisms involved...
  7. doi request reprint Intracerebral atypical presentation of echinococcosis in a child
    Iacopo Sardi
    Division of Neurosurgery, A Meyer Children s Hospital, University of Florence, Florence, Italy
    Pediatr Neurosurg 44:350-2. 2008
  8. ncbi request reprint Emerging treatments and gene expression profiling in high-risk medulloblastoma
    Iacopo Sardi
    Department of Pediatrics, Onco hematology and Neuro surgery Units, University of Florence Medical School, A Meyer Children s Hospital, Florence, Italy
    Paediatr Drugs 9:81-96. 2007
    ....
  9. doi request reprint Detection of doxorubicin hydrochloride accumulation in the rat brain after morphine treatment by mass spectrometry
    Iacopo Sardi
    Department of Onco Hematology and Neuro Surgery Units, A Meyer Children s Hospital, viale G Pieraccini 24, 50139 Florence, Italy
    Cancer Chemother Pharmacol 67:1333-40. 2011
    ..We explored the feasibility of active modification of the blood-brain barrier protection, by using morphine pretreatment, to allow doxorubicin accumulation in the brain in an animal model...
  10. doi request reprint Glioneuronal tumor with neuropil-like islands: clinical, morphologic, immunohistochemical, and molecular features of three pediatric cases
    Anna Maria Buccoliero
    Pathology Unit, Anna Meyer Children s Hospital, Florence, Italy
    Pediatr Dev Pathol 15:352-60. 2012
    ..In conclusion, glioneuronal tumor with neuropil-like islands can affect children, arise in the spinal cord, and show ependymal features in its glial component. A high-dose chemoradiotherapy program is effective...
  11. doi request reprint Pediatric rhabdoid meningioma: a morphological, immunohistochemical, ultrastructural and molecular case study
    Anna Maria Buccoliero
    Department of Biomedicine, Careggi Hospital, Florence, Italy
    Neuropathology 31:59-65. 2011
    ..Rhabdoid meningiomas rarely occur in children. Owing to its rarity, each new case should be recorded to produce a better clinical, pathological, molecular, prognostic and therapeutic characterization of this lesion...
  12. doi request reprint Merlin expression in pediatric anaplastic ependymomas real time PCR study
    Anna Maria Buccoliero
    Department of Human Pathology and Oncology, University of Florence, Morgagni 85, Florence, Italy
    Fetal Pediatr Pathol 29:245-54. 2010
    ..Statistical analysis did not prove significant differences. Our results suggest that NF2 alterations are not typical of intracranial anaplastic ependymomas...
  13. doi request reprint Pediatric brain tumors: mutations of two dioxygenases (hABH2 and hABH3) that directly repair alkylation damage
    Valentina Cetica
    Onco Hematology Unit, Department of Pediatrics, Florence Medical School, A Meyer Children s Hospital, Viale Pieraccini 24, 50139, Florence, Italy
    J Neurooncol 94:195-201. 2009
    ..This is the first study of hABH2 and hABH3 in pediatric brain tumors; further molecular investigations of their mutations and expression may help determine their role in response to chemotherapy...
  14. doi request reprint Primary cerebral myxofibrosarcoma: clinical, morphologic, immunohistochemical, molecular, and ultrastructural study of an infrequent tumor in an extraordinary localization
    Anna Maria Buccoliero
    Department of Biomedicine, Careggi Hospital, Florence, Italy
    J Pediatr Hematol Oncol 33:e279-83. 2011
    ..We believe each new case should be recorded to produce a better clinical, pathologic, molecular, prognostic, and therapeutic characterization of this lesion...
  15. ncbi request reprint Successful treatment of metastatic βHCG-secreting germ cell tumor occurring 3 years after total resection of a pineal mature teratoma
    Stefania Cardellicchio
    Neuro Oncology Unit, Department of Paediatric Medicine, Meyer Children s University Hospital, viale G Pieraccini 24, 50139, Florence, Italy
    Eur J Pediatr 173:1011-5. 2014
    ....
  16. doi request reprint Infant ependymoma in a 10-year AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) experience with omitted or deferred radiotherapy
    Maura Massimino
    Department of Pediatrics, Fondazione IRCCS, Istituto Nazionale Tumori, Milano, Italy
    Int J Radiat Oncol Biol Phys 80:807-14. 2011
    ..We treated 41 children under the age of 3 years with intracranial ependymoma between 1994 and 2003...
  17. doi request reprint Pediatric sinonasal neuroendocrine carcinoma after treatment of retinoblastoma
    Alessandro Franchi
    Department of Human Pathology and Oncology, University of Florence, 50134 Florence, Italy
    Hum Pathol 40:750-5. 2009
    ..These tumors represent a peculiar subset of undifferentiated sinonasal neoplasms with extremely aggressive clinical behavior...
  18. ncbi request reprint Teratoid hepatoblastoma
    Anna Maria Buccoliero
    Department of Human Pathology and Oncology, Careggi Hospital, University of Florence, Florence, Italy
    Fetal Pediatr Pathol 27:274-81. 2008
    ..We speculate on the histogenesis of teratoid hepatoblastoma and discuss its association with chemotherapy...
  19. doi request reprint Low-dose cisplatin-etoposide regimen for patients with optic pathway glioma: a report of four cases and literature review
    Stefania Cardellicchio
    Neuro Oncology Unit, Department of Pediatrics, Meyer Children s Hospital, Florence, Italy
    Neuropediatrics 45:42-9. 2014
    ..We suggest that VA and VF can be considered as the most accurate parameters for defining the start of chemotherapy and tumor response. ..
  20. doi request reprint Pediatric primary anaplastic ganglioglioma: a case report and review of the literature
    Silvia Scoccianti
    Radiation Oncology Unit, Azienda Ospedaliera Universitaria Careggi, Florence, Italy
    Pediatr Neurosurg 48:35-41. 2012
    ..Prospective studies are needed to identify an appropriate chemotherapy schedule and to define biological factors in order to select those patients with a poor prognosis, who are to be treated with a more aggressive therapy...
  21. pmc Type A microsatellite instability in pediatric gliomas as an indicator of Turcot syndrome
    Laura Giunti
    Medical Genetics Unit, Meyer Children s University Hospital, Florence, Italy
    Eur J Hum Genet 17:919-27. 2009
    ....
  22. doi request reprint Congenital/Infantile fibrosarcoma of the colon: morphologic, immunohistochemical, molecular, and ultrastructural features of a relatively rare tumor in an extraordinary localization
    Anna Maria Buccoliero
    Department of Human Pathology and Oncology, University of Florence, Careggi Hospital, Firenze, Italy
    J Pediatr Hematol Oncol 30:723-7. 2008
    ..The algorithm for the diagnosis of congenital/infantile fibrosarcoma, especially outside the usual localizations, should comprise morphologic, immunohistochemical, molecular, and ultrastructural studies...
  23. doi request reprint Dedifferentiated peripheral chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of four cases
    Alessandro Franchi
    Division of Anatomic Pathology, Department of Critical Care Medicine and Surgery, University of Florence Medical School, Viale G B Morgagni 85, 50134 Florence, Italy
    Virchows Arch 460:335-42. 2012
    ..PDGFRβ could represent a potential target for treatments with receptor tyrosine kinase inhibitors in peripheral DCS...
  24. doi request reprint Tumour suppressor gene TP53 mutations in atypical vascular lesions of breast skin following radiotherapy
    Raffaella Santi
    Division of Pathological Anatomy, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    Histopathology 58:455-66. 2011
    ..The aim of the present study was to investigate alterations of tumour suppressor gene TP53 in a series of radiation-induced AVL and angiosarcomas (AS)...
  25. doi request reprint Pineal germinoma morphological features in a liquid-based cerebrospinal fluid sample
    Anna Maria Buccoliero
    Department of Biomedicine, Careggi Hospital, Florence, Italy
    Diagn Cytopathol 36:645-6. 2008
  26. doi request reprint Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy: recurrence, genetically related cancer, or second primary?
    Alberto Deganello
    Department of Otolaryngology Head and Neck Surgery, University of Florence, Florence, Italy
    Cancer 116:1291-7. 2010
    ..In the attempt to characterize the genetic bases of recurrent head and neck squamous cell carcinoma (HNSCC) after radiotherapy (RT), the authors compared the molecular profiles of primary tumors and recurrences...
  27. ncbi request reprint Qualitative and quantitative analysis of angiogenetic factors in transitional cell bladder carcinoma: relationship with clinical course at 10 years follow-up
    Riccardo Bartoletti
    Department of Urology, University of Florence, Viale Pieraccini 18, 50139 Florence, Italy
    Oncol Rep 14:251-5. 2005
    ....
  28. ncbi request reprint Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer
    Fabio Cianchi
    Department of General Surgery, Medical School, University of Florence, Florence, Italy
    Clin Cancer Res 10:2694-704. 2004
    ..We aimed at evaluating the possible interaction between the nitric oxide and COX-2 pathways, and its effect on promoting tumor angiogenesis...
  29. ncbi request reprint E-cadherin mRNA expression analysis in evaluating the natural history of urothelial bladder cell carcinoma: results from a long-term follow-up study
    Tommaso Cai
    Department of Urology, University of Florence, I 50011 Bagno a Ripoli, Florence, Italy
    Oncol Rep 17:925-30. 2007
    ..We stress that a long follow-up period is needed to evaluate the role of molecular factors in predicting prognosis in patients affected by bladder UC...
  30. ncbi request reprint Stomal recurrence following total laryngectomy: clinical and molecular analysis of a series
    Roberto Santoro
    Department of Oto neuro ophthalmologic Surgical Sciences, University of Florence, Florence, Italy
    Ann Otol Rhinol Laryngol 112:594-9. 2003
    ..Our analysis supports the hypothesis that a subset of SRs after TL may be second primary tumors, genetically unrelated to the primary laryngeal lesion...
  31. pmc Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis
    Fabio Cianchi
    Department of General Surgery, Medical School, University of Florence, Florence, Italy
    Am J Pathol 162:793-801. 2003
    ..Western and Northern blot analyses confirmed the up-regulation of the iNOS protein and gene in the tumor specimens as compared with normal mucosa. NO seems to play a role in colorectal cancer growth by promoting tumor angiogenesis...
  32. ncbi request reprint Molecular profiling of high-risk neuroblastoma by cDNA array
    Iacopo Sardi
    Unita di Oncoematologia, Ospedale Pediatrico A Meyer, Via L Giordano 13, 50132 Florence, Italy
    Int J Mol Med 9:541-5. 2002
    ..Thus, the sensitive cDNA array may provide new insight into many aspects of pediatric tumors and play crucial role in the administration of adjuvant therapy of patients with neuroblastoma...