Giorgio Sandrini

Summary

Affiliation: University of Pavia
Country: Italy

Publications

  1. ncbi request reprint Electrophysiological evidence for trigeminal neuron sensitization in patients with migraine
    Giorgio Sandrini
    Laboratory of Pain Psychophysiology, Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Neurosci Lett 317:135-8. 2002
  2. ncbi request reprint Nitroglycerin induces hyperalgesia in rats--a time-course study
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Eur J Pharmacol 464:159-62. 2003
  3. ncbi request reprint Botulinum toxin and neuromotor rehabilitation: An integrated approach to idiopathic cervical dystonia
    Cristina Tassorelli
    Neurorehabilitation Unit, C Mondino Institute of Neurology Foundation, Dept of Neurological Sciences, University of Pavia, Italy
    Mov Disord 21:2240-3. 2006
  4. doi request reprint Medication overuse headache and applicability of the ICHD-II diagnostic criteria: 1-year follow-up study (CARE I protocol)
    N Ghiotto
    Headache Unit and University Centre for Adaptive Disorders and Headache, Mondino Institute of Neurology Foundation, Pavia, Italy
    Cephalalgia 29:233-43. 2009
  5. ncbi request reprint Diagnostic issues in chronic daily headache
    G Sandrini
    University Center for Adaptive Disorders and Headache, C Mondino Foundation, Via Palestro, Pavia 3 27100, Italy
    Curr Pain Headache Rep 5:551-6. 2001
  6. ncbi request reprint The lower limb flexion reflex in humans
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    Prog Neurobiol 77:353-95. 2005
  7. ncbi request reprint Uncommon primary headaches
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Curr Opin Neurol 19:299-304. 2006
  8. ncbi request reprint Effects of sleep on spinal nociceptive reflexes in humans
    G Sandrini
    Department of Neurological Sciences, University of Pavia, Italy
    Sleep 24:13-7. 2001
  9. ncbi request reprint Asymmetrical reduction of the nociceptive flexion reflex threshold in cluster headache
    G Sandrini
    Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, IRCCS, C Mondino Foundation, University of Pavia, Italy
    Cephalalgia 20:647-52. 2000
  10. ncbi request reprint Effects of hypnosis on diffuse noxious inhibitory controls
    G Sandrini
    Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, IRCCS, C Mondino Foundation, University of Pavia, Via Palestro 3, 27100, Pavia, Italy
    Physiol Behav 69:295-300. 2000

Detail Information

Publications76

  1. ncbi request reprint Electrophysiological evidence for trigeminal neuron sensitization in patients with migraine
    Giorgio Sandrini
    Laboratory of Pain Psychophysiology, Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Neurosci Lett 317:135-8. 2002
    ..These findings suggest that sensorimotor mechanisms and/or pain control systems at the trigeminal level are impaired in migraine. The bilateral location of these abnormalities seems to point to a centrally located dysfunction...
  2. ncbi request reprint Nitroglycerin induces hyperalgesia in rats--a time-course study
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Eur J Pharmacol 464:159-62. 2003
    ..Nitroglycerin induced a significant reduction in the latency of the tail flick 2 and 4 h after its administration. Similarly, formalin-induced pain-related behaviour increased significantly 2 and 4 h after nitroglycerin administration...
  3. ncbi request reprint Botulinum toxin and neuromotor rehabilitation: An integrated approach to idiopathic cervical dystonia
    Cristina Tassorelli
    Neurorehabilitation Unit, C Mondino Institute of Neurology Foundation, Dept of Neurological Sciences, University of Pavia, Italy
    Mov Disord 21:2240-3. 2006
    ..7 vs. -4.85 points) and subjective pain (-13.35 vs. 6.95 points) scores. Association of BTX-A therapy with a specific program of physical therapy may improve ICD treatment outcome...
  4. doi request reprint Medication overuse headache and applicability of the ICHD-II diagnostic criteria: 1-year follow-up study (CARE I protocol)
    N Ghiotto
    Headache Unit and University Centre for Adaptive Disorders and Headache, Mondino Institute of Neurology Foundation, Pavia, Italy
    Cephalalgia 29:233-43. 2009
    ..In addition, the present findings point to the need for a more objective criterion to quantify headache frequency after drug withdrawal...
  5. ncbi request reprint Diagnostic issues in chronic daily headache
    G Sandrini
    University Center for Adaptive Disorders and Headache, C Mondino Foundation, Via Palestro, Pavia 3 27100, Italy
    Curr Pain Headache Rep 5:551-6. 2001
    ..Although some theoretic problems remain unresolved, it seems that the next revision of the IHS classification can no longer ignore the existence of CDH...
  6. ncbi request reprint The lower limb flexion reflex in humans
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    Prog Neurobiol 77:353-95. 2005
    ....
  7. ncbi request reprint Uncommon primary headaches
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Curr Opin Neurol 19:299-304. 2006
    ..The recent classification offers an interesting opportunity to evaluate the clinical role and to discuss the mechanisms of some of the more relevant uncommon primary headaches...
  8. ncbi request reprint Effects of sleep on spinal nociceptive reflexes in humans
    G Sandrini
    Department of Neurological Sciences, University of Pavia, Italy
    Sleep 24:13-7. 2001
    ..There was evidence of further latency prolongation during REM sleep. It was also during REM sleep that the maximum increase in the amplitude and duration of the reflex were recorded...
  9. ncbi request reprint Asymmetrical reduction of the nociceptive flexion reflex threshold in cluster headache
    G Sandrini
    Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, IRCCS, C Mondino Foundation, University of Pavia, Italy
    Cephalalgia 20:647-52. 2000
    ..e. corneal reflex, pain pressure threshold). On the whole, these data tie in with the view of an impairment of the pain control system, which parallels the periodicity of the disorder in the episodic form...
  10. ncbi request reprint Effects of hypnosis on diffuse noxious inhibitory controls
    G Sandrini
    Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, IRCCS, C Mondino Foundation, University of Pavia, Via Palestro 3, 27100, Pavia, Italy
    Physiol Behav 69:295-300. 2000
    ..It seems likely that DNICs and hypnosis use the same descending inhibitory pathways for the control of pain. The susceptibility of the subject is a critical factor in hypnotically induced analgesia...
  11. ncbi request reprint Different effect of high doses of naloxone on spinal reflexes in normal subjects and chronic paraplegic patients
    G Sandrini
    Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, University of Pavia, Italy
    Neurosci Lett 261:5-8. 1999
    ..Our data suggest that under normal conditions the opiatergic modulation of the nociceptive reflex is not functionally active whereas the tonic inhibitory modulation of the monosynaptic reflex is mediated by descending pathways...
  12. ncbi request reprint Abnormal modulatory influence of diffuse noxious inhibitory controls in migraine and chronic tension-type headache patients
    G Sandrini
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, University of Pavia, Pavia, Italy
    Cephalalgia 26:782-9. 2006
    ..Impairment of endogenous supraspinal pain modulation systems may contribute to the development and/or maintenance of central sensitization in primary headaches...
  13. ncbi request reprint Eletriptan: a review and new perspectives
    Giorgio Sandrini
    University of Pavia, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Expert Rev Neurother 6:1413-21. 2006
    ..Eletriptan showed the most favorable cost-effectiveness profile when compared with other agents in its class...
  14. doi request reprint Facilitated temporal summation of pain at spinal level in Parkinson's disease
    Armando Perrotta
    Department of Neurology, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Mov Disord 26:442-8. 2011
    ....
  15. doi request reprint Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: a double-blind, placebo-controlled, cross-over study
    Armando Perrotta
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Eur J Pain 15:482-90. 2011
    ..In migraineurs the susceptibility to develop migraine attack after GTN administration seems to be a specific trait of a subgroup of patients linked to a supersensitivity of the pain system to GTN...
  16. ncbi request reprint Behavioral responses and Fos activation following painful stimuli in a rodent model of Parkinson's disease
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, Neurological Institute C Mondino, Pavia, Italy
    Brain Res 1176:53-61. 2007
    ....
  17. doi request reprint Pisa syndrome in Parkinson's disease: clinical, electromyographic, and radiological characterization
    Cristina Tassorelli
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Mov Disord 27:227-35. 2012
    ..This postural abnormality deserves attention and proper early treatment to prevent comorbidities and pain...
  18. ncbi request reprint Comparative analysis of the neuronal activation and cardiovascular effects of nitroglycerin, sodium nitroprusside and L-arginine
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Institute of Neurology C Mondino Foundation and University Centre for the Study of Adaptive Disorders and Headache UCADH, Pavia, Italy
    Brain Res 1051:17-24. 2005
    ..Of the NO-related drugs tested in this study, only nitroglycerin confirmed its ability to activate brainstem areas implicated in nociception...
  19. doi request reprint Role of central dopaminergic circuitry in pain processing and nitroglycerin-induced hyperalgesia
    Rosaria Greco
    Interdepartmental Research Center for Parkinson s Disease, IRCCS Neurological Institute C Mondino, Pavia, Italy
    Brain Res 1238:215-23. 2008
    ....
  20. doi request reprint The role of rehabilitation in deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a pilot study
    Cristina Tassorelli
    Department of Neurological Sciences, Interdepartmental Centre of Research on Parkinson s Disease ICRPD, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    Parkinsonism Relat Disord 15:675-81. 2009
    ..The reported findings suggest that rehabilitation may play an important role in the correction of specific functional impairments caused by or associated with DBS in PD...
  21. ncbi request reprint Prostaglandins, glutamate and nitric oxide synthase mediate nitroglycerin-induced hyperalgesia in the formalin test
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Center for the Study of Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Eur J Pharmacol 534:103-7. 2006
    ..The present findings point to the role of prostaglandins, NO synthesis and glutamate activity in the induction of nitroglycerin-induced hyperalgesia...
  22. ncbi request reprint Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia
    Cristina Tassorelli
    Laboratories of Integrative Autonomic Systems and Neurophysiology of Pain, IRCCS Institute of Neurology C Mondino Foundation, University Center for Adaptive Disorders and Headache, Pavia, Italy
    Drugs 63:9-22. 2003
    ....
  23. doi request reprint Lack of trigemino-cervical reflexes in progressive supranuclear palsy
    Michelangelo Bartolo
    Department of Neurological Sciences, University of Pavia, Pavia, Italy
    Mov Disord 23:1475-9. 2008
    ..These findings indicate that PSP patients are unable to react to the painful stimuli to the face, suggesting a generalized impairment of the brainstem circuits mediating TCRs...
  24. doi request reprint Four-week trunk-specific rehabilitation treatment improves lateral trunk flexion in Parkinson's disease
    Michelangelo Bartolo
    Neurorehabilitation Unit, Institute of Neurology Casimiro Mondino Foundation IRCCS, Pavia, Italy
    Mov Disord 25:325-31. 2010
    ..Our findings show that significant improvements in axial posture and trunk mobility can be obtained through the 4-week rehabilitation programme described, with a parallel improvement in clinical status...
  25. doi request reprint Effect of sex and estrogens on neuronal activation in an animal model of migraine
    Rosaria Greco
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation and University of Pavia, Pavia, Italy
    Headache 53:288-96. 2013
    ..In this study, we evaluated the influence of sex and estrogen treatment on nitroglycerin (NTG)-induced neuronal activation in the rat brain...
  26. pmc Effects of anandamide in migraine: data from an animal model
    Rosaria Greco
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, University of Pavia, Via Mondino, 2, 27100 Pavia, Italy
    J Headache Pain 12:177-83. 2011
    ..The study confirms that a dysfunction of the endocannabinoid system may contribute to the development of migraine attacks and that a pharmacological modulation of CB receptors can be useful for the treatment of migraine pain...
  27. doi request reprint Temporal profile of vascular changes induced by systemic nitroglycerin in the meningeal and cortical districts
    Rosaria Greco
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Cephalalgia 31:190-8. 2011
    ..Systemic nitroglycerin (NTG), a NO donor, is a well-accepted experimental model of migraine. In this study we have examined the effects of NTG on the meningeal and cortical blood flow in rats...
  28. pmc Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group study
    Giorgio Sandrini
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 12:427-33. 2011
    ....
  29. ncbi request reprint The H reflex from the abductor brevis hallucis muscle in healthy subjects
    Maurizio Versino
    Fondazione Istituto Neurologico C Mondino IRCCS, Via Mondino 2, 27100 Pavia, Italy
    Muscle Nerve 36:39-46. 2007
    ..The Hmax latency and Hmax/Mmax amplitude ratio, but not Hmax amplitude, proved to be reliable. The usefulness of the H reflex from ABH in the evaluation of S2 radiculopathies is described...
  30. doi request reprint Eletriptan
    Giorgio Sandrini
    IRCCS C Mondino Institute of Neurology Foundation, Department of Neurology, Via Mondino 2, Pavia, Italy
    Expert Opin Drug Metab Toxicol 5:1587-98. 2009
    ..Eletriptan showed the most favorable cost-effectiveness profile when compared with other agents in its class...
  31. ncbi request reprint Activation of the transcription factor NF-kappaB in the nucleus trigeminalis caudalis in an animal model of migraine
    Rosaria Greco
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Neurological Institute C Mondino Foundation and University Centre for the Study of Adaptive Disorder and Headache UCADH, Via Palestro 3, 27100 Pavia, Italy
    Neurotoxicology 26:795-800. 2005
    ..Furthermore, these findings pave the way to new bio-molecular and pharmacological avenues for the development of innovative migraine therapies...
  32. ncbi request reprint Effects of nimesulide on nitric oxide-induced hyperalgesia in humans--a neurophysiological study
    Giorgio Sandrini
    Psychophysiology of Pain Laboratory, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Eur J Pharmacol 450:259-62. 2002
    ..These data suggest a central effect for nimesulide, possibly related to a reduction of nociceptive activity at spinal level...
  33. ncbi request reprint A role for brain cyclooxygenase-2 and prostaglandin-E2 in migraine: effects of nitroglycerin
    Cristina Tassorelli
    IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Int Rev Neurobiol 82:373-82. 2007
    ..This activity may explain the pronociceptive effect of NTG described in animal and human models of pain. Most importantly, these findings point to mediators and areas that may be relevant for migraine pathogenesis and treatment...
  34. doi request reprint Chronic daily headache
    Giuseppe Nappi
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Italy
    Expert Rev Neurother 8:361-84. 2008
    ..This article reviews various aspects of CDH: classification issues, pathophysiological hypotheses and therapeutic (pharmacological and nonpharmacological) approaches...
  35. ncbi request reprint Changes in nociceptive flexion reflex threshold across the menstrual cycle in healthy women
    Cristina Tassorelli
    Psychophysiology of Pain Laboratory, University Centre for Adaptive Disorders and Headache UCADH, IRCCS C Mondino Foundation, Department of Neurological Sciences, University of Pavia, Italy
    Psychosom Med 64:621-6. 2002
    ..We assessed the influence of changes in steroid hormones across the menstrual cycle on the spinal nociceptive reflex...
  36. ncbi request reprint Ocular motor myotonic phenomenon in myotonic dystrophy
    Maurizio Versino
    Fondazione Istituto Neurologico C Mondino, IRCCS, Pavia, Italy
    Ann N Y Acad Sci 956:401-4. 2002
  37. pmc Ocular motor myotonic phenomenon in myotonic dystrophy
    M Versino
    Fondazione Istituto Neurologico C Mondino, IRCCS, Dipartimento di Scienze Neurologiche, Universita di Pavia, Via Palestro 3, 27100 Pavia, Italy
    J Neurol Neurosurg Psychiatry 72:236-40. 2002
    ..To detect disconjugate ocular motor abnormalities and a possible extraocular muscle myotonic phenomenon in patients with myotonic dystrophy (MyD)...
  38. ncbi request reprint Eletriptan vs sumatriptan: a double-blind, placebo-controlled, multiple migraine attack study
    G Sandrini
    University Centre for Adaptive Disorders and Headache, IRCCSC Mondino Foundation, Pavia, Italy
    Neurology 59:1210-7. 2002
    ..To compare the efficacy of oral eletriptan, 40 mg and 80 mg, and oral sumatriptan, 50 mg and 100 mg, in the acute treatment of migraine...
  39. ncbi request reprint Psychiatric comorbidity in chronic daily headache
    A P Verri
    University Centre for Adaptive Disorders and Headache, Section of Pavia, Italy
    Cephalalgia 18:45-9. 1998
    ..The most frequent diagnosis was a comorbidity of anxiety and mood disorders. The comorbidity of psychiatric disorders and headache has important implications as far as treatment is concerned...
  40. ncbi request reprint Neurophysiological tests and neuroimaging procedures in non-acute headache: guidelines and recommendations
    G Sandrini
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, Pavia, Italy
    Eur J Neurol 11:217-24. 2004
    ..Although many of the examinations described are of little or no value in the clinical setting, most of the tools have a vast potential for further exploring the pathophysiology of headaches and the effects of pharmacological treatment...
  41. ncbi request reprint Eye movement abnormalities in myotonic dystrophy
    M Versino
    Fondazione Istituto Neurologico C Mondino, Universita di Pavia, Italy
    Electroencephalogr Clin Neurophysiol 109:184-90. 1998
    ..Accordingly we classified the oculomotor abnormalities detected as neurogenic in 11 MD patients and as myogenic in another 10, but in some subjects belonging to the second group concomitant CNS impairment is not to be excluded...
  42. ncbi request reprint [Accidents and headache]
    Ennio Pucci
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    G Ital Med Lav Ergon 33:394-8. 2011
    ....
  43. pmc Almotriptan in the treatment of migraine
    Giorgio Sandrini
    University Centre for Adaptive, Disorders and Headache, IRCCS, C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Neuropsychiatr Dis Treat 3:799-809. 2007
    ..On the basis of these findings, almotriptan may be considered a therapeutic option for the acute treatment of migraine attacks...
  44. doi request reprint Is hemicrania continua a single entity or the association of two headache forms? Considerations from a case report
    Marta Allena
    University Centre for the Study of Adaptive Disorders and Headache, University of Pavia and Headache Centre, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Headache 50:877-81. 2010
    ..The analysis of this case raises interesting issues regarding the proper place of HC among the primary headache forms...
  45. doi request reprint Dysphagia in multiple sclerosis: from pathogenesis to diagnosis
    Cristina Tassorelli
    Department of Neurological Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy
    Neurol Sci 29:S360-3. 2008
    ..An integrated approach is proposed to define the severity of dysphagia and to devise the most appropriate therapeutic/rehabilitative methodology...
  46. ncbi request reprint Muscle MRI in adult-onset acid maltase deficiency
    Anna Pichiecchio
    Department of Neuroradiology, Fondazione Istituto Neurologico C Mondino IRCCS, Via Palestro 3, 27100, Pavia, Italy
    Neuromuscul Disord 14:51-5. 2004
    ..Further control studies in a larger cohort are needed to evaluate the specificity of these findings...
  47. ncbi request reprint Report of eight new cases of hypnic headache and mini-review of the literature
    Natascia Ghiotto
    Headache Treatment and Diagnosis Centre, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 17:211-9. 2002
    ..9% of the cases and unilateral attacks in 36%. Hypnic headache will be included in the fourth chapter (Other Primary Headaches) of the revised edition of the above-mentioned classification (IHC 2nd Edition)...
  48. ncbi request reprint Cervicogenic headache: evaluation of the original diagnostic criteria
    F Antonaci
    Headache Centre, University of Pavia, IRCCS C Mondino Foundation, Pavia, Italy
    Cephalalgia 21:573-83. 2001
    ....
  49. pmc Estimation of human trunk movements by wearable strain sensors and improvement of sensor's placement on intelligent biomedical clothes
    Paolo Tormene
    Department of Computer Engineering and Systems Science, University of Pavia, Pavia, Italy
    Biomed Eng Online 11:95. 2012
    ....
  50. pmc Cerebrovascular diseases at the C. Mondino National Institute of Neurology: from Ottorino Rossi to the present day
    Giuseppe Micieli
    IRCCS C Mondino National Institute of Neurology Foundation, Pavia, Italy
    Funct Neurol 26:87-95. 2011
    ....
  51. ncbi request reprint Tolerability of the triptans: clinical implications
    Giuseppe Nappi
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, University of Pavia, Italy
    Drug Saf 26:93-107. 2003
    ..There is no evidence of a teratogenic risk of triptans in pregnant women taking these drugs...
  52. ncbi request reprint Trigeminofacial reflexes in primary headaches
    A Proietti Cecchini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, University of Pavia, Italy
    Cephalalgia 23:33-41. 2003
    ..e. dishabituation pattern and reduced pain threshold. We review the contribution of trigeminofacial reflex studies in the light of those recent data supporting the view of a dysfunctional sensory processing in primary headache...
  53. doi request reprint Reduced habituation of trigeminal reflexes in patients with episodic cluster headache during cluster period
    A Perrotta
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Cephalalgia 28:950-9. 2008
    ..The lack of habituation in CH, more pronounced than in migraine, points to abnormal processing of sensory stimuli at the trigeminal level that could be driven by hypothalamic dysfunction during the cluster period...
  54. pmc From drug-induced headache to medication overuse headache. A short epidemiological review, with a focus on Latin American countries
    Marta Allena
    IRCCS Neurological Institute C Mondino Foundation, University Centre for Headache and Adaptive Disorders, Pavia Section, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 10:71-6. 2009
    ..Limited amount of data exists on the burden and impact of MOH in Latin American Countries. In this review, we summarise the reliable information from the literature on the epidemiological impact of MOH...
  55. ncbi request reprint Effects of dothiepin on nociceptive flexion reflex and diffuse noxious inhibitory controls in humans
    G Sandrini
    Department of Neurology C Mondino Foundation, University of Pavia, Italy
    Eur J Pharmacol 243:99-102. 1993
    ..Our data suggest a serotonergic modulation of diffuse noxious inhibitory controls in humans...
  56. ncbi request reprint A new 5-HT2 antagonist (ritanserin) in the treatment of chronic headache with depression. A double-blind study vs amitriptyline
    G Nappi
    Dept. of Neurology IRCCS C. Mondino, University of Pavia, Italy
    Headache 30:439-44. 1990
    ..Our data confirm the usefulness of these methods as markers of chronic headache with depression...
  57. pmc Patients with headache and functional dyspepsia present meal-induced hypersensitivity of the stomach
    Ennio Pucci
    University Centre for Adaptive Disorders and Headache UCADH, University of Pavia, IRCCS C Mondino, Via Mondino 2, I 27100 Pavia, Italy
    J Headache Pain 6:223-6. 2005
    ..DTh after meal was lower in dyspeptic headache patients than in HV and dyspeptic without headache patients. Patients with migraine and functional dyspepsia may be characterised by meal-induced hypersensitivity of the stomach...
  58. doi request reprint The clinical neurophysiology of tension-type headache
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache UCADH and Department of Neurological Sciences, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Handb Clin Neurol 97:367-76. 2010
    ..It concludes that the majority of neurophysiological studies on TTH present serious methodological flaws that will have to be overcome to allow further understanding of the mechanisms of TTH...
  59. ncbi request reprint A randomised, double-blind, dose-ranging study to evaluate efficacy and safety of three doses of botulinum toxin type A (Botox) for the treatment of spastic foot
    F Mancini
    Parkinson s Disease and Movement Disorders Center, IRCCS C Mondino Institute of Neurology, Via Mondino 2, I 27100, Pavia, Italy
    Neurol Sci 26:26-31. 2005
    ..In particular, the medium BTX dosages (320 UI spread over 2-5 muscles) were found to be both safe and effective in producing long-lasting improvement of spastic foot dysfunction...
  60. ncbi request reprint Focus on trial endpoints of clinical relevance and the use of almotriptan for the acute treatment of migraine
    G Sandrini
    Department of Neurological Rehabilitation, University Centre for Adaptive Disorders and Headache, Pavia, Italy
    Int J Clin Pract 59:1356-65. 2005
    ....
  61. pmc Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, mu
    G Sandrini
    University Centre for Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Int J Clin Pract 61:1256-69. 2007
    ..Additionally, in the group taking Indoprocaf, two different oral formulations were tested: effervescent tablets and encapsulated coated tablets...
  62. ncbi request reprint [Prevalence of primary headache related to work activity in a group of hospital workers undergoing periodic visits (D. Lgs. 626/94 s.s.m. ed i.)]
    E Pucci
    Centro Interuniversitario Cefalee e Disordini Adattativi, Universita degli Studi di Pavia, IRCCS C Mondino, Pavia, Italy
    G Ital Med Lav Ergon 25:448-52. 2003
    ..The results obtained suggest that specific occupational conditions such as shift work and P.C. use may play an important role in headache development even in the presence of a wide number of professional risk factors...
  63. ncbi request reprint Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches
    G Sances
    Headache Unit, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation Institute of Neurology, Pavia, Italy
    Cephalalgia 24:110-9. 2004
    ..6%, specificity 100% and accuracy 92.9%. NPT is an easy, low-cost and reliable method for supporting the diagnosis of migraine without aura and cluster headache...
  64. pmc A narrative review on the management of medication overuse headache: the steep road from experience to evidence
    Paolo Rossi
    IRCCS Neurological Institute C Mondino Foundation, University Centre for Headache and Adaptive Disorders UCADH, Pavia Section, Pavia, Italy
    J Headache Pain 10:407-17. 2009
    ....
  65. ncbi request reprint Chronic daily headache. How should it be included in the IHS classification?
    G Nappi
    University Centre for Adaptive Disorders and Headache, Unit of Pavia 1, IRCCS C Mondino Foundation, Italy
    Headache 39:197-203. 1999
    ..Although some theoretical problems remain unresolved, it seems to us that the next revision of the IHS classification can no longer ignore the existence of chronic daily headache...
  66. doi request reprint Role of calcitonin gene-related peptide and substance P in different models of pain
    R Greco
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Cephalalgia 28:114-26. 2008
    ....
  67. ncbi request reprint [Headache as "sentinel" symptom in personnel involved in the preparation and administration of antineoplastic drugs]
    E Pucci
    Centro Interuniversitario Cefalee e Disordini Adattativi, Universita degli Studi, Pavia, IRCCS C Mondino, Pavia, Italy
    G Ital Med Lav Ergon 27:412-6. 2005
    ..These findings suggest that headache is the onset symptom of the toxic effect of antiblastic chemiotherapics in the medical personnel involved in drug preparation and administration...
  68. ncbi request reprint Effects of diffuse noxious inhibitory controls on temporal summation of the RIII reflex in humans
    Mariano Serrao
    Department of Neurology and Otolaryngology, University of Rome La Sapienza, Italy
    Pain 112:353-60. 2004
    ....
  69. ncbi request reprint Experimental muscle pain decreases the frequency threshold of electrically elicited muscle cramps
    Mariano Serrao
    Rehabilitation Unit, Polo Pontino ICOT, Latina, University of Rome La Sapienza, Rome, Italy
    Exp Brain Res 182:301-8. 2007
    ..9 +/- 3.2 muV and 101.6 +/- 6.0 Hz; P < 0.05). The results suggest that nociceptive muscle afferent activity induced by injection of hypertonic saline facilitates the generation of electrically elicited muscle cramps...
  70. ncbi request reprint Kinematic and electromyographic study of the nociceptive withdrawal reflex in the upper limbs during rest and movement
    Mariano Serrao
    Department of Neurology and Otolaryngology, Santa Maria Goretti Hospital, Latina, La Sapienza, University of Rome, 00185 Rome, Italy
    J Neurosci 26:3505-13. 2006
    ..Study of the upper limb NWR may provide a window onto the spinal neural control mechanisms operating during movement...
  71. doi request reprint Modulation of spinal inhibitory reflex responses to cutaneous nociceptive stimuli during upper limb movement
    Romildo Don
    Movement Analysis Laboratory, Department of Physical Medicine and Rehabilitation, University of Rome La Sapienza, Rome, Italy
    Eur J Neurosci 28:559-68. 2008
    ..Study of the nociceptive inhibitory reflexes during movement offers new and more profound insights into the functional anatomical organization of the spinal interneuronal network mediating sensory-motor integration...
  72. ncbi request reprint Instrumental investigations in primary headache. An updated review and new perspectives
    Lars Friberg
    Department of Clinical Physiology and Nuclear Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Funct Neurol 18:127-44. 2003
    ..This article reviews many of the most important literature references relevant to this topic and looks at the prospects for future research...
  73. ncbi request reprint The effects of botulinum toxin in spasticity and headaches: a common key?
    Giorgio Sandrini
    Funct Neurol 23:61. 2008
  74. ncbi request reprint Lower limb manual muscle testing in the early stages of Charcot-Marie-Tooth disease type 1A
    Paolo Vinci
    Section of Rehabilitation of Charcot Marie Tooth Disease and other Neuromuscular Disorders, Specialized Rehabilitation Hospital L Spolverini, Ariccia, Italy
    Funct Neurol 21:159-63. 2006
    ..87% were weak in the standing test; all the proximal muscles were strong. In the large majority of patients in the early stages of CMT 1A, the intrinsic foot muscles are very weak and the leg and proximal muscles are strong...
  75. ncbi request reprint Differences in the EMG pattern of leg muscle activation during locomotion in Parkinson's disease
    Giovanni Albani
    Department of Neurology, IRCCS Italian Auxology Centre, Piancavallo, Verbania, Italy
    Funct Neurol 18:165-70. 2003
    ..Poor recruitment of the GM characterises parkinsonian gait in general; this pattern is much more marked in parkinsonian patients with freezing of gait, who show a loss of GM adaptation to variation of locomotion speed...
  76. ncbi request reprint Use of the sustained pain-free plus no adverse events endpoint in clinical trials of triptans in acute migraine
    David W Dodick
    Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
    CNS Drugs 21:73-82. 2007
    ....