Alessandra Russo


Affiliation: University of Catania
Country: Italy


  1. request reprint
    Russo A, Borrelli F. Bacopa monniera, a reputed nootropic plant: an overview. Phytomedicine. 2005;12:305-17 pubmed
    ..Moreover, other clinical studies have to be encouraged, also to evidence any side effects and possible interactions between this herbal medicine and synthetic drugs...
  2. Russo A, Caggia S, Piovano M, Garbarino J, Cardile V. Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: role of Hsp70 protein. Chem Biol Interact. 2012;195:1-10 pubmed publisher
    ..The combination of vicanicin (4) and protolichesterinic acid (5) with other anti-prostate cancer therapies could be considered a promising strategy that warrants further in vivo evaluation. ..
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    Russo A, Cardile V, Lombardo L, Vanella L, Acquaviva R. Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells. J Nutr Biochem. 2006;17:103-8 pubmed
    ..These results suggest that also genistin, due to its antioxidant and anticarcinogenic properties, contributes to the overall biological activity of soy and could have promising applications in the field of dermatology. ..
  4. Madrid A, Cardile V, González C, Montenegro I, Villena J, Caggia S, et al. Psoralea glandulosa as a potential source of anticancer agents for melanoma treatment. Int J Mol Sci. 2015;16:7944-59 pubmed publisher
    ..In summary, our study provides the first evidence that P. glandulosa may be considered a source of useful molecules in the development of analogues with more potent efficacy against melanoma cells. ..
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    Russo A, Borrelli F, Campisi A, Acquaviva R, Raciti G, Vanella A. Nitric oxide-related toxicity in cultured astrocytes: effect of Bacopa monniera. Life Sci. 2003;73:1517-26 pubmed
    ..This data supports the traditional use of BM and indicates that this medicinal plant has a therapeutic potential in treatment or prevention of neurological diseases. ..
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    Russo A, Piovano M, Clericuzio M, Lombardo L, Tabasso S, Chamy M, et al. Putrescine-1,4-dicinnamide from Pholiota spumosa (Basidiomycetes) inhibits cell growth of human prostate cancer cells. Phytomedicine. 2007;14:185-91 pubmed
  7. Cardile V, Avola R, Graziano A, Piovano M, Russo A. Cytotoxicity of demalonyl thyrsiflorin A, a semisynthetic labdane-derived diterpenoid, to melanoma cells. Toxicol In Vitro. 2018;47:274-280 pubmed publisher
  8. Russo A, Cardile V, Graziano A, Avola R, Bruno M, Rigano D. Involvement of Bax and Bcl-2 in Induction of Apoptosis by Essential Oils of Three Lebanese Salvia Species in Human Prostate Cancer Cells. Int J Mol Sci. 2018;19: pubmed publisher
    ..These results suggest it could be profitable to further investigate the effects of these essential oils for their possible use as anticancer agents in prostate cancer, alone or in combination with chemotherapy agents. ..
  9. Russo A, Piovano M, Lombardo L, Garbarino J, Cardile V. Lichen metabolites prevent UV light and nitric oxide-mediated plasmid DNA damage and induce apoptosis in human melanoma cells. Life Sci. 2008;83:468-74 pubmed publisher

More Information


  1. Cardile V, Graziano A, Avola R, Piovano M, Russo A. Potential anticancer activity of lichen secondary metabolite physodic acid. Chem Biol Interact. 2017;263:36-45 pubmed publisher
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    Russo A, Izzo A, Borrelli F, Renis M, Vanella A. Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage. Phytother Res. 2003;17:870-5 pubmed
    ..Moreover, this experimental evidence suggests that because of its antioxidant activity, this Ayurvedic drug may be useful in the treatment of human pathologies in which free radical production plays a key role...
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    Russo A, Cardile V, Lombardo L, Vanella L, Vanella A, Garbarino J. Antioxidant activity and antiproliferative action of methanolic extract of Geum quellyon Sweet roots in human tumor cell lines. J Ethnopharmacol. 2005;100:323-32 pubmed
    ..The effect evidenced in Caco-2 cells can be in part correlated to a modulation of redox-sensitive mechanisms...
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    Russo A, Lombardo L, Troncoso N, Garbarino J, Cardile V. Rosmarinus officinalis extract inhibits human melanoma cell growth. Nat Prod Commun. 2009;4:1707-10 pubmed
    ..No statistically significant increase in LDH release was observed in melanoma cells, correlated to a fragmentation of genomic DNA, determined by COMET assay...
  5. Russo A, Cardile V, Caggia S, GUNTHER G, Troncoso N, Garbarino J. Boldo prevents UV light and nitric oxide-mediated plasmid DNA damage and reduces the expression of Hsp70 protein in melanoma cancer cells. J Pharm Pharmacol. 2011;63:1219-29 pubmed publisher
    ..In addition, we investigated the growth inhibitory activity of this natural product against human melanoma cells (M14)...