Research Topics
| C RuggieroSummaryAffiliation: University of Foggia Country: Italy Publications
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Detail Information
Publications
Potentially inappropriate drug prescriptions and risk of hospitalization among older, Italian, nursing home residents: the ULISSE projectCarmelinda Ruggiero
Department of Clinical and Experimental Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
Drugs Aging 27:747-58. 2010..Little information is available about the prevalence of potentially inappropriate drug prescriptions (PIDPs) and the related health adverse outcomes among nursing home (NH) residents...
High basal metabolic rate is a risk factor for mortality: the Baltimore Longitudinal Study of AgingCarmelinda Ruggiero
National Institute on Aging, NIH, Harbor Hospital, Baltimore, MD 21225, USA
J Gerontol A Biol Sci Med Sci 63:698-706. 2008..We evaluate the longitudinal changes in BMR and the relationship between BMR and mortality in the Baltimore Longitudinal Study of Aging (BLSA) participants...- Inappropriate drug prescriptions among older nursing home residents: the Italian perspectiveCarmelinda Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Drugs Aging 26:15-30. 2009..Overall, this review reveals that the prevalence of PIDP is high in both North American and European nursing homes and highlights the urgent need for intervention trials testing strategies to reduce the health and social burden of PIDP... - Omega-3 polyunsaturated fatty acids and immune-mediated diseases: inflammatory bowel disease and rheumatoid arthritisC Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Curr Pharm Des 15:4135-48. 2009..In both IBD and RA further clinical trials with large sample size are needed to clarify the efficacy of omega-3 PUFA as a treatment... 
White blood cell count and mortality in the Baltimore Longitudinal Study of AgingCarmelinda Ruggiero
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
J Am Coll Cardiol 49:1841-50. 2007..We investigated the secular trend in white blood cell (WBC) count and the relationship between WBC count and mortality between 1958 and 2002...- Uric acid and dementia in community-dwelling older personsCarmelinda Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Dement Geriatr Cogn Disord 27:382-9. 2009..Epidemiological studies found that hyperuricemia is associated with conditions leading to dementia. Our aim is to investigate the relationship between UA levels and dementia in older persons... - Dietary antioxidants as potential pharmacological agents for ischemic strokeA Cherubini
Department of Clinical and Experimental Medicine, Institute of Gerontology and Geriatrics, Policlinico Monteluce, Pad E, Via Brunamonti, 51, 06100, Perugia, Italy
Curr Med Chem 15:1236-48. 2008.... - Validation of the Italian version of the falls efficacy scale international (FES-I) and the short FES-I in community-dwelling older personsC Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Santa Maria della Misericordia, Perugia, Italy
Arch Gerontol Geriatr 49:211-9. 2009..The Short FES-I is highly comparable with the FES-I. We conclude that the FES-I and the Short FES-I are excellent instruments to asses FF in Italian older subjects and they may be used in future research projects and clinical trials... - Role of antioxidants in atherosclerosis: epidemiological and clinical updateA Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Policlinico Monteluce, Padiglione E, Via Brunamonti, 06122, Perugia Italy
Curr Pharm Des 11:2017-32. 2005..Future studies should probably select patients in a context of high-oxidative stress / low-antioxidant defence, to verify if antioxidants may really prove useful as therapeutic anti-atherosclerotic agents... - The endeavor of high maintenance homeostasis: resting metabolic rate and the legacy of longevityCarmelinda Ruggiero
J Gerontol A Biol Sci Med Sci 61:466-71. 2006..We predict that measures of resting metabolic rate will be introduced in geriatric clinical practice to gather information on the degree of multisystem dysregulation, exhaustion of energy reserve, and risk of irreversible frailty... - Low plasma selenium concentrations and mortality among older community-dwelling adults: the InCHIANTI StudyFulvio Lauretani
Tuscany Regional Agency, Florence, Italy
Aging Clin Exp Res 20:153-8. 2008..We examined the relationship between plasma selenium levels at enrollment and all-cause mortality over a 6-year period among participants in the InCHIANTI study... - Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 yearsCarmelinda Ruggiero
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
Am J Cardiol 100:115-21. 2007..In conclusion, our study suggests that in a population-based cohort, baseline UA and changes in circulating UA during 3 years of follow-up predict changes in circulating CRP independent of relevant confounders, including baseline IL-6... - Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markersLuigi Ferrucci
Intramural Research Program, National Institute on Aging, Baltimore, MD 21225, USA
Br J Haematol 136:849-55. 2007..Unexplained anaemia was characterised by unexpectedly low EPO and low lymphocyte count. Unexplained anaemia is associated with reduced kidney EPO response, low levels of pro-inflammatory markers and low lymphocyte counts... - Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI studyMarcello Maggio
National Institute on Aging, NIH, NIA ASTRA Unit at Harbor Hospital, 3001 S Hanover St, Baltimore, MD 21225, USA
Am J Physiol Endocrinol Metab 292:E353-8. 2007..Further studies are needed to support the notion that raising SHBG is a potential therapeutic target for prevention and treatment of MetS... - Relation of angiotensin-converting enzyme inhibitor treatment to insulin-like growth factor-1 serum levels in subjects >65 years of age (the InCHIANTI study)Marcello Maggio
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, USA
Am J Cardiol 97:1525-9. 2006..This may be 1 of the mechanisms by which ACE inhibitors might slow the decreases in muscle strength and physical function that are often observed in older subjects... - Uric acid and inflammatory markersCarmelinda Ruggiero
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, NIH, Baltimore, MD, USA
Eur Heart J 27:1174-81. 2006..Epidemiological studies have recently shown that UA may be a risk factor for cardiovascular diseases and a negative prognostic marker for mortality in subjects with pre-existing heart failure... - Treatment with angiotensin-converting enzyme inhibitors is associated with a reduction in short-term mortality in older patients with acute ischemic strokeGiovanni Zuliani
Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, 44100 Ferrara, Italy
J Gerontol A Biol Sci Med Sci 60:463-5. 2005..We tested the hypothesis that angiotensin-converting enzyme inhibitors (A-I) might affect short-term (30 day) mortality in older persons with severe acute ischemic stroke...