R M Ruggeri

Summary

Affiliation: University of Messina
Country: Italy

Publications

  1. doi request reprint Serum hepatocyte growth factor is increased in Hashimoto's thyroiditis whether or not it is associated with nodular goiter as compared with healthy non-goitrous individuals
    R M Ruggeri
    Unit of Endocrinology, Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Messina, Italy
    J Endocrinol Invest 32:465-9. 2009
  2. doi request reprint Chronic idiopathic urticaria and Graves' disease
    R M Ruggeri
    Unit of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    J Endocrinol Invest 36:531-6. 2013
  3. doi request reprint Follicular variant of papillary thyroid carcinoma presenting as toxic nodule in an adolescent: coexistent polymorphism of the TSHR and Gsα genes
    Rosaria Maddalena Ruggeri
    Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Thyroid 23:239-42. 2013
  4. doi request reprint Association of autonomously functioning thyroid nodules with Hashimoto's thyroiditis: study on a large series of patients
    R M Ruggeri
    Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Sezione di Endocrinologia, Policlinico Universitario G Martino, 98125 Messina, Italy
    Exp Clin Endocrinol Diabetes 119:621-7. 2011
  5. ncbi request reprint Spontaneous recovery from isolated post-traumatic central hypogonadism in a woman
    Rosaria M Ruggeri
    Clinical Experimental Department of Medicine and Pharmacology, Section of Endocrinology, Policlinico Universitario G Martino, University of Messina, Messina, Italy
    Hormones (Athens) 9:332-7. 2010
  6. doi request reprint Supra-acetabular brown tumor due to primary hyperparathyroidism associated with chronic renal failure
    Rosaria M Ruggeri
    Department of Clinical Experimental Medicine and Pharmacology, University of Messina, Messina, Italy
    ScientificWorldJournal 10:799-805. 2010
  7. ncbi request reprint Immunohistochemical localization and functional characterization of somatostatin receptor subtypes in a corticotropin releasing hormone- secreting adrenal phaeochromocytoma: review of the literature and report of a case
    Rosaria M Ruggeri
    Section of Endocrinology of University of Messina, Messina, Italy
    Eur J Histochem 53:1-6. 2009
  8. ncbi request reprint Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations
    R M Ruggeri
    Department of Medicine and Pharmacology, Section of Endocrinology, University of Messina, 98125 Messina, Italy
    J Endocrinol Invest 31:946-9. 2008
  9. ncbi request reprint Immunoexpression of the CD30 ligand/CD30 and IL-6/IL-6R signals in thyroid autoimmune diseases
    R M Ruggeri
    Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Italy
    Histol Histopathol 21:249-56. 2006
  10. ncbi request reprint Distinctive expression of STAT3 in papillary thyroid carcinomas and a subset of follicular adenomas
    M Trovato
    Department of Pathology, Policlinico Universitario, Messina, Italy
    Histol Histopathol 18:393-9. 2003

Detail Information

Publications20

  1. doi request reprint Serum hepatocyte growth factor is increased in Hashimoto's thyroiditis whether or not it is associated with nodular goiter as compared with healthy non-goitrous individuals
    R M Ruggeri
    Unit of Endocrinology, Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Messina, Italy
    J Endocrinol Invest 32:465-9. 2009
    ..Some growth factors and cytokines are known to cooperate with TSH in thyroid nodular growth, but few data are available on their circulating levels in Hashimoto's thyroiditis (HT)...
  2. doi request reprint Chronic idiopathic urticaria and Graves' disease
    R M Ruggeri
    Unit of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    J Endocrinol Invest 36:531-6. 2013
    ..Here we review this topic with particular regard to the association between Graves' disease and CIU. The possible pathogenetic mechanisms and the clinical implications of such an association are discussed. ..
  3. doi request reprint Follicular variant of papillary thyroid carcinoma presenting as toxic nodule in an adolescent: coexistent polymorphism of the TSHR and Gsα genes
    Rosaria Maddalena Ruggeri
    Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
    Thyroid 23:239-42. 2013
    ..Herein, we present a 15-year-old girl with a papillary thyroid carcinoma of 3.5 cm in diameter, which was functionally autonomous and scintigraphically hot...
  4. doi request reprint Association of autonomously functioning thyroid nodules with Hashimoto's thyroiditis: study on a large series of patients
    R M Ruggeri
    Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Sezione di Endocrinologia, Policlinico Universitario G Martino, 98125 Messina, Italy
    Exp Clin Endocrinol Diabetes 119:621-7. 2011
    ..This study evaluates the magnitude of such association, elaborating the clinical and biochemical characteristics of HT and AFTN...
  5. ncbi request reprint Spontaneous recovery from isolated post-traumatic central hypogonadism in a woman
    Rosaria M Ruggeri
    Clinical Experimental Department of Medicine and Pharmacology, Section of Endocrinology, Policlinico Universitario G Martino, University of Messina, Messina, Italy
    Hormones (Athens) 9:332-7. 2010
    ..Hypopituitarism is a recognized complication of Traumatic Brain Injury (TBI). Resolution of established anterior pituitary hormones deficiency is rare...
  6. doi request reprint Supra-acetabular brown tumor due to primary hyperparathyroidism associated with chronic renal failure
    Rosaria M Ruggeri
    Department of Clinical Experimental Medicine and Pharmacology, University of Messina, Messina, Italy
    ScientificWorldJournal 10:799-805. 2010
    ....
  7. ncbi request reprint Immunohistochemical localization and functional characterization of somatostatin receptor subtypes in a corticotropin releasing hormone- secreting adrenal phaeochromocytoma: review of the literature and report of a case
    Rosaria M Ruggeri
    Section of Endocrinology of University of Messina, Messina, Italy
    Eur J Histochem 53:1-6. 2009
    ....
  8. ncbi request reprint Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations
    R M Ruggeri
    Department of Medicine and Pharmacology, Section of Endocrinology, University of Messina, 98125 Messina, Italy
    J Endocrinol Invest 31:946-9. 2008
    ..Mutations of the genes encoding the alpha subunit of the stimulatory G protein (Gs) and of the inhibiting Gi2 protein (GNAS1 and GNAI2 genes, respectively) have been described in various endocrine neoplasias, including pituitary tumors...
  9. ncbi request reprint Immunoexpression of the CD30 ligand/CD30 and IL-6/IL-6R signals in thyroid autoimmune diseases
    R M Ruggeri
    Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Italy
    Histol Histopathol 21:249-56. 2006
    ..The two systems could contribute to drive the autoimmune response skewing toward a Th2 phenotype and this appears to be correlated with the lymphoid aggregate grade...
  10. ncbi request reprint Distinctive expression of STAT3 in papillary thyroid carcinomas and a subset of follicular adenomas
    M Trovato
    Department of Pathology, Policlinico Universitario, Messina, Italy
    Histol Histopathol 18:393-9. 2003
    ..Because of the communeness of a HGF/c-met/STAT3 pattern between all PTC and a subset of FA, we speculate that a fraction of FA may progress to PTC...
  11. ncbi request reprint HGF/C-MET system pathways in benign and malignant histotypes of thyroid nodules: an immunohistochemical characterization
    R M Ruggeri
    Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Sezione di Endocrinologia, University of Messina, Messina, Italy
    Histol Histopathol 27:113-21. 2012
    ..Herein we first investigate the simultaneous expression of HGF, c-met, STAT3, phosphor-STAT3, PI3K, Akt and Rho in thyroid nodules...
  12. ncbi request reprint Expression of CD30 ligand and CD30 receptor in normal thyroid and benign and malignant thyroid nodules
    M Trovato
    Dipartimento di Patologia Umana, University of Messina, School of Medicine, Italy
    Thyroid 11:621-8. 2001
    ..In conclusion, CD30L/CD30 signaling is activated only past the colloid nodule stage, most frequently in an autocrine fashion...
  13. ncbi request reprint Co-expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) in thyroid nodules is associated with co-expression of CD30 ligand/CD30 receptor
    R M Ruggeri
    Section of Endocrinology, Clinical Experimental Department of Medicine and Pharmacology, University of Messina School of Medicine, Messina, Italy
    J Endocrinol Invest 25:959-66. 2002
    ..In the normal thyroid tissue, colloid nodules, and another subset of benign and malignant thyroid nodules, IL-6 expression is under control of signals other than CD30L/CD30...
  14. ncbi request reprint Expression of hepatocyte growth factor in Hashimoto's thyroiditis with nodular lesions
    R M Ruggeri
    Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Sezione di Endocrinologia, Policlinico Universitario G Martino, Universita di Messina, Messina, Italy
    Eur J Histochem 51:193-8. 2007
    ..These data indicate that HGF may play a role in cell proliferation processes occurring in thyroid glands affected by HT, probably under the regulation of the lymphoid infiltrate...
  15. pmc The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization
    R M Ruggeri
    Unit of Endocrinology, Clinical Experimental, Department of Medicine and Pharmacology, University of Messina, Messina, Italy
    Eur J Histochem 54:e24. 2010
    ..Finally, the expression of such molecules in HT may be regulated by lymphoid infiltrate...
  16. ncbi request reprint Cell proliferation parameters and apoptosis indices in pituitary macroadenomas
    R M Ruggeri
    Section of Endocrinology, Department of Medicine and Pharmacology, University of Messina, Messina, 98125, Italy
    J Endocrinol Invest 35:473-8. 2012
    ..Pituitary adenomas are usually well-differentiated tumors but may show locally aggressive behavior...
  17. doi request reprint Increased serum interleukin-22 levels in patients with PRL-secreting and non-functioning pituitary macroadenomas
    S Cannavo
    Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, AOU Policlinico G Martino Pad H, Floor 4, Via Consolare Valeria 1, 98125, Messina, Italy
    Pituitary 17:76-80. 2014
    ..We also demonstrated the expression of IL22R in all PRL-omas and in 60 % of NFPAs. ..
  18. ncbi request reprint Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial
    S Benvenga
    Cattedra and Sezione di Endocrinologia, Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina School of Medicine, 98125 Messina, Italy
    J Clin Endocrinol Metab 86:3579-94. 2001
    ..Because hyperthyroidism depletes the body deposits of carnitine and since carnitine has no toxicity, teratogenicity, contraindications and interactions with drugs, carnitine can be of clinical use...
  19. ncbi request reprint Thyroid hormone autoantibodies in primary Sjögren syndrome and rheumatoid arthritis are more prevalent than in autoimmune thyroid disease, becoming progressively more frequent in these diseases
    R M Ruggeri
    Clinical Experimental Department of Medicine and Pharmacology, University of Messina, School of Medicine, Policlinico Universitario, Italy
    J Endocrinol Invest 25:447-54. 2002
    ....
  20. ncbi request reprint An analytical model for improving absorbed dose calculation accuracy in non spherical autonomous functioning thyroid nodule
    E Amato
    Department of Radiological Sciences, University of Messina, Messina, Italy
    Q J Nucl Med Mol Imaging 55:560-6. 2011
    ..To optimize the treatment, pretherapeutic dosimetry should account also for the dependence of deposited energy on the nodule geometry...