Research Topics
| Pietro RubegniSummaryAffiliation: University of Siena Country: Italy Publications
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Detail Information
Publications
A single centre melanoma thickness trend (1985-2009) in relation to skin areas accessible and non-accessible to self-inspectionPietro Rubegni
Department of Clinical Medicine and Immunological Sciences, Dermatology Section, University Hospital of Siena, Italy
Australas J Dermatol 53:32-6. 2012..The objective was to determine historical changes in thickness, melanoma proportions and anatomical site of presentation over a 25-year period in our Department...
Skin diseases in geriatric patients: our experience from a public skin outpatient clinic in SienaP Rubegni
Section of Dermatology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
G Ital Dermatol Venereol 147:631-6. 2012..However, little data is available regarding geriatric skin diseases. In order to provide rapid access to specialist help, in 2003 we created a dermatology clinic dedicated only to geriatric patients age 65 and older...- Photolocalized purpura during levofloxacin therapyPietro Rubegni
Department of Clinical Medicine and Immunological Sciences, Dermatology Section, University of Siena, Siena, Italy
Photodermatol Photoimmunol Photomed 28:105-7. 2012..This was a rare case of solar capillaritis. Purpuric eruptions on photoexposed skin should be considered another unusual side effect of levofloxacin... - Melanocytic skin lesions and pregnancy: digital dermoscopy analysisPietro Rubegni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Siena, Italy
Skin Res Technol 13:143-7. 2007..Our purpose was to objectively determine, by digital dermoscopy analysis (DDA), any dermoscopic changes of acquired melanocitic nevi during pregnancy and after 1 year from delivery... - Encephalocraniocutaneous lipomatosis (Haberland syndrome) with bilateral cutaneous and visceral involvementP Rubegni
Department of Dermatology, University of Siena, Siena, Italy
Clin Exp Dermatol 28:387-90. 2003..Here we report a case of Haberland syndrome with bilateral involvement which underscores the extreme heterogeneity of clinical presentation of this and related syndromes... - Terbinafine-induced acute generalized exanthematous pustulosisP Rubegni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Siena, Italy
G Ital Dermatol Venereol 143:151-5. 2008..The case illustrates once again the role of terbinafine in AGEP and reminds us that early diagnosis of AGEP is important to avoid unnecessary investigations and/or the administration of antibiotics... - Case 4. Umbilical endometriosisP Rubegni
Departments of Dermatology and Pathology, University of Siena, Siena, Italy
Clin Exp Dermatol 28:571-2. 2003 - Role of extracorporeal photochemotherapy in patients with refractory chronic graft-versus-host diseaseP Rubegni
Department of Clinical Medicine and Immunological Science, Sections of Dermatology, University of Siena, Siena, Italy
Br J Haematol 130:271-5. 2005..ECP affected the course of the disease positively in 78% (25/32) of our cases... - CD4+CD25+ lymphocyte subsets in chronic graft versus host disease patients undergoing extracorporeal photochemotherapyP Rubegni
Department of Clinical Medicine and Immunological Sciences Section of Dermatology, University of Siena, Italy
Int J Immunopathol Pharmacol 20:801-7. 2007..Our study confirms that changes in the percentage of CD4+CD25+ T cells induced by ECP could be a central aspect in the cascade of immune events leading to the immunological and clinical effects of this treatment in patients with cGvHD... - Acral malignant melanoma and striated palmoplantar keratoderma (Brunauer-Fohs-Siemens syndrome): a fortuitous association?Pietro Rubegni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Siena, Italy
Dermatol Surg 30:1539-42. 2004..Unlike other palmoplantar keratodermas, no association with visceral or skin cancer has ever been reported... - Cutaneous colorimetric evaluation of serum concentrations of bilirubin in healthy term neonates: a new methodological approachPietro Rubegni
Department of Dermatology, University of Siena, Siena, Italy
Skin Res Technol 11:70-5. 2005..The aim of the present study was to determine whether non-invasive measurement of skin colour combined with appropriate clinico-statistical methodology can be used to better quantify SB in the first days of life... - Thalidomide in the treatment of Kaposi's sarcomaPietro Rubegni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Siena, Italy
Dermatology 215:240-4. 2007..If a large area or internal organs are affected or other treatments fail, chemotherapy is used. Recently some authors have reported their encouraging experience in the use of thalidomide in patients with AIDS-related KS... - Venous ulcers of the lower limbs due to congenital thalidomide-related valve defectPietro Rubegni
Section of Dermatology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
Angiology 58:491-3. 2007..The coexistence of cutaneous ulcers in our case might be coincidental but may be related to a congenital valve defect (hypoagenesis) caused by thalidomide... - A case of Darier's disease successfully treated with topical tacrolimusP Rubegni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Italy
J Eur Acad Dermatol Venereol 20:84-7. 2006..We report a case of extensive Darier's disease successfully treated with topical tacrolimus, after suspension of oral isotretrinoin due to major depression... - Images in clinical medicine. Bisphosphonate-associated contact stomatitisPietro Rubegni
University of Siena, Siena, Italy
N Engl J Med 355:e25. 2006 - Digital image management project for dermatological health care environments: a new dedicated software and review of the literaturePietro Rubegni
Department of Dermatology, University of Siena, Tuscany, Italy
Skin Res Technol 15:148-56. 2009..To describe a digital image management system dedicated to dermatological health care environments and to compare it with other existing softwares for digital image storage... - A case of sebaceous nevus sindrome (Schimmelpen-ning-Feuerstein-Mims syndrome)P Rubegni
Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
G Ital Dermatol Venereol 144:617-9. 2009..The particularity of our case lies in the late diagnosis. The authors believe that early diagnosis and awareness of the potential presence of neoplasms are important for those involved in the care of patients with SNS... - Differentiation between pigmented Spitz naevus and melanoma by digital dermoscopy and stepwise logistic discriminant analysisP Rubegni
Department of Dermatology, University of Siena, Italy
Melanoma Res 11:37-44. 2001..Thus the combined use of digital dermoscopy and stepwise logistic discriminant analysis made it possible to single out the best objective variables for distinguishing PSN and melanoma... - Objective follow-up of atypical melanocytic skin lesions: a retrospective studyPietro Rubegni
Department of Clinical Medicine and Immunological Science, Policlinico Le Scotte, Siena, Italy
Arch Dermatol Res 302:551-60. 2010.... - Digital dermoscopy analysis and artificial neural network for the differentiation of clinically atypical pigmented skin lesions: a retrospective studyPietro Rubegni
Department of Dermatology and Department of Heart Surgery and Biomedical Technology, University of Siena LegaTumori, Siena, Italy
J Invest Dermatol 119:471-4. 2002.... - Digital dermoscopy analysis for automated diagnosis of pigmented skin lesionsPietro Rubegni
Department of Dermatology, University of Siena, Siena, Italy
Clin Dermatol 20:309-12. 2002 - Automated diagnosis of pigmented skin lesionsPietro Rubegni
Department of Dermatology, University of Siena, Siena, Italy
Int J Cancer 101:576-80. 2002..In conclusion, the good diagnostic performance and high speed in reading and analyzing lesions (real time) of our method constitute an important step in the direction of automated diagnosis of pigmented skin lesions... - Sweet's syndrome and Chlamydia pneumoniae infectionP Rubegni
Department of Dermatology, University of Siena, Italy
J Am Acad Dermatol 44:862-4. 2001.... - Digital dermoscopy analysis of atypical pigmented skin lesions: a stepwise logistic discriminant analysis approachP Rubegni
Department of Dermatology, University of Siena, Policlinico Le Scotte, 53100 Siena, Italy
Skin Res Technol 8:276-81. 2002..If correctly applied, this technique can be useful for the diagnosis of pigmented skin lesions... - Evaluation of cutaneous melanoma thickness by digital dermoscopy analysis: a retrospective studyPietro Rubegni
Section of Dermatology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
Melanoma Res 20:212-7. 2010..However, further studies should be performed in a prospective setting before the clinical application... - Objective melanoma progressionPietro Rubegni
Department of Clinical Medicine and Immunological Science, Dermatology Section, University of Siena, Siena, Italy
Skin Res Technol 17:69-74. 2011..The purpose of our study was to retrospectively determine objective changes in melanoma over a 3-24-month observation period... - The 'common mole' from the point of view of digital dermoscopy analysis: subjective vs. objective evaluation of easy pigmented skin lesionsM Burroni
Department of Dermatology, University of Siena, Siena, Italy
J Eur Acad Dermatol Venereol 17:28-33. 2003..In recent years, certain research groups have developed equipment and methods, such as digital dermoscopy analysis, that enable objective evaluation of pigmented skin lesions... - Geriatric teledermatology: store-and-forward vs. face-to-face examinationP Rubegni
Department of Clinical Medicine and Immunological Science, Dermatology Section, University of Siena, Italy
J Eur Acad Dermatol Venereol 25:1334-9. 2011.... - Inter- and intra-variability of pigmented skin lesions: could the ABCD rule be influenced by host characteristics?Marco Burroni
Department of Clinical Medicine and Immunological Sciences Section of Dermatology, University of Siena, Siena, Italy
Skin Res Technol 10:193-9. 2004..R.L, siena, Italy)... - Melanoma computer-aided diagnosis: reliability and feasibility studyMarco Burroni
Department of Dermatology, University of Siena, Italy
Clin Cancer Res 10:1881-6. 2004..Whether this would improve early diagnosis of melanoma and/or reducing unnecessary surgery needs to be demonstrated by a randomized clinical trial... - Impact of digital dermoscopy analysis on the decision to follow up or to excise a pigmented skin lesion: a multicentre studyMarco Burroni
Department of Dermatology, Section of Dermatology, University of Siena, Siena, Italy
Skin Res Technol 17:451-60. 2011..Does a higher rate of excision of pigmented skin lesions (PSL) increase the rate of detected melanomas?.. - Utility of tumour-infiltrating CD25+FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanomaClelia Miracco
Department of Human Pathology and Oncology, Section of Pathological Anatomy, University of Siena, Siena 53100, Italy
Oncol Rep 18:1115-22. 2007..The analysis of a larger series of patients and correlation with other clinical parameters, such as distant metastases and/or patient survival, are mandatory for validating its use as a prognostic indicator... - Digital surface microscopy analysis of conjunctival pigmented lesions: a preliminary studyGian Marco Tosi
Department of Ophthalmology and Neurosurgery, University of Siena, Siena, Italy
Melanoma Res 14:375-80. 2004..Moreover, this preliminary study allowed us to determine which objective variables could be important for distinguishing between benign CPLs and conjunctival MMs... - Subcutaneous panniculitis lymphoma: erythema nodosum-likeMassimiliano Risulo
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Italy
Clin Lymphoma Myeloma 7:239-41. 2006.... - Macrophage migration inhibitory factor protein and mRNA expression in cutaneous melanocytic tumoursClelia Miracco
Sezione di Anatomia Patologica, Dipartimento di Patologia Umana e Oncologia, Universita di Siena, 53100 Siena, Italy
Int J Oncol 28:345-52. 2006.... - A case of idiopathic granulomatous cheilitis and vulvitisPaolo Sbano
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Siena, Italy
Int J Dermatol 46:720-1. 2007..After 6 months of therapy, the upper lip showed significant improvement and erythema and desquamation in the genital area showed slight improvement, but genital edema was unaffected... - Cutaneous metastases from adenocarcinoma of the rete testisPietro Rubegni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Italy
J Cutan Pathol 33:181-4. 2006..We discuss the differential diagnosis to this rare entity, which include metastatic adenocarcinoma, serous tumor of the testis, and mesothelioma of the tunica vaginalis... - Extracorporeal photopheresis in graft-versus-host diseaseMaria Rosaria Carcagnì
Dipartimento di Medicina Clinica e Scienze Immunologiche, Sezione di Dermatologia, Siena, Italy
J Dtsch Dermatol Ges 6:451-7. 2008..GvHD is usually treated with corticosteroids and other immunosuppressants which do not always succeed in arresting its evolution. Extracorporeal photochemotherapy has been used in patients with both acute and chronic GvHD... - A nodule on a boy's backGiovambattista De Aloe
University of Siena, Siena, Italy
Arch Dermatol 143:417-22. 2007 - Dermoscopy of pigmented skin lesions: results of a consensus meeting via the InternetGiuseppe Argenziano
Department of Dermatology, Second University of Naples, Italy
J Am Acad Dermatol 48:679-93. 2003..53). CONCLUSION: The virtual Consensus Net Meeting on Dermoscopy represents a valid tool for better standardization of the dermoscopic terminology and, moreover, opens up a new territory for diagnosing and managing pigmented skin lesions... 
Extracorporeal photopheresis affects co-stimulatory molecule expression and interleukin-10 production by dendritic cells in graft-versus-host disease patientsM Di Renzo
Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, Italy
Clin Exp Immunol 151:407-13. 2008....- Evaluation of MDR1, LRP, MRP, and topoisomerase IIalpha gene mRNA transcripts before and after interferon-alpha, and correlation with the mRNA expression level of the telomerase subunits hTERT and TEP1 in five unselected human melanoma cell linesClelia Miracco
Istituto di Anatomia e Istologia Patologica, Policlinico Le Scotte, Viale Bracci 6, I 53100 Siena, Italy
Int J Oncol 23:213-20. 2003..IFN-alpha modulates differently MDR gene transcripts in human melanoma cell lines. Positive correlation between TEP1 and LRP also seems to identify them as common targets of IFN-alpha effects... - Ocular manifestations of chronic graft-versus-host disease in patients treated with extracorporeal photochemotherapyE Motolese
Department of Ophthalmology and Neurosurgery, University of Siena, Siena, Italy
Eur J Ophthalmol 17:961-9. 2007..ECP is a relatively new therapeutic approach based on the biological effects of psoralen 8-methoxypsoralen (8-MOP) and ultraviolet A light (UVA) on mononuclear cells collected by apheresis, and reinfused into the patient... - Mechanism of action of extracorporeal photochemotherapy in chronic graft-versus-host diseaseM Fimiani
Istituto di Scienze Dermatologiche, Universita degli Studi di Siena, Policlinico Le Scotte, 53100 Siena, Italy
Br J Dermatol 150:1055-60. 2004..Only a better and more complete understanding of the various mechanisms involved will enable this interesting new therapy to be made more effective and selective... - Modified Karhunen-Loéve expansion for evaluating skin-colour-associated melanoma risk factorsG Cevenini
Institute of Thoracic and Cardiovascular Surgery and Biomedical Technology, University of Siena, Italy
Comput Biol Med 30:171-89. 2000.... - Rothmund-Thomson syndrome (Thomson-type) and myelodysplasiaE Pianigiani
Department of Dermatology, University of Siena, Siena, Italy
Pediatr Dermatol 18:422-5. 2001..The patient was kept under hematologic surveillance for myelodysplastic syndrome. Bone marrow transplantation was considered unnecessary at present... - ECP-treated lymphocytes of chronic graft-versus-host disease patients undergo apoptosis which involves both the Fas/FasL system and the Bcl-2 protein familyM Di Renzo
Department of Internal Medicine and Immunological Sciences, University of Siena, 53100 Siena, Italy
Arch Dermatol Res 295:175-82. 2003..In conclusion, in patients affected by cGVHD, ECP induced apoptosis of lymphocytes with the involvement of both the Fas/FasL system and the Bcl-2 protein family... - Intraoperative skin expansion in emergency repair of the scalpE Pianigiani
Department of Dermatology, University of Siena, Siena, Italy
J Dermatolog Treat 12:25-8. 2001..Besides an excellent immediate functional result, acceptable aesthetic results, confirmed 6 months later, were also obtained... - Extracorporeal photopheresis affects interleukin (IL)-10 and IL-12 production by monocytes in patients with chronic graft-versus-host diseaseM Di Renzo
Department of Internal Medicine and Immunology, University of Siena, 53100 Siena, Italy
Br J Dermatol 153:59-65. 2005..Extracorporeal photopheresis (ECP) has recently been introduced as an alternative treatment for cases of cGVHD refractory to conventional immunosuppressive treatment, but its mechanism of action is not yet clear... - Recurrent Mondor's disease resolved after exeresis of abdominal lipomaP Rubegni
Department of Dermatology, University of Siena, Italy
Dermatol Surg 25:563-5. 1999..Mondor's disease is a rare disorder characterized by superficial thrombophlebitis, classically of the thoracic-epigastric and/or lateral thoracic veins. The etiopathogenesis of the disease is not entirely clear... - Conjunctival edema and alopecia of the external third of the eyebrows in a patient with Meige syndromeP Rubegni
Department of Dermatology, University of Siena, Policlinico Le Scotte, I 53100 Siena, Italy
Graefes Arch Clin Exp Ophthalmol 238:98-100. 2000..To describe a patient with Meige syndrome in whom we observed the coexistence of hereditary lymphedema of the lower legs, conjunctival edema and alopecia of the lateral third of the eyebrows... - Quantitative characterization and study of the relationship between constitutive-facultative skin color and phototype in CaucasiansP Rubegni
Department of Dermatology, University of Siena, Italy
Photochem Photobiol 70:303-7. 1999.... - Inhibition of maturation of human monocyte-derived dendritic cells in a patient with Mycobacterium avium infectionM Di Renzo
Department of Clinical Medicine and Immunological Sciences, Azienda Ospedaliera Universitaria Senese, U O di Medicina III, Policlinico Le Scotte, 53100 Siena, Italy
Int J Immunopathol Pharmacol 19:391-7. 2006..Inhibition of DC maturation by the in vivo infection with Mycobacterium avium may be an immune-evasion mechanism used by the pathogen because incompletely matured DCs may not activate effector T cells efficiently in vivo... - Chronic erythematous desquamative plaques of the eyelids: discoid lupus erythematosis (DLE)Elisa Pianigiani
University of Siena, Siena, Italy
Arch Dermatol 138:527-32. 2002 - Dysplastic naevus vs. in situ melanoma: digital dermoscopy analysisM Burroni
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Policlinico 'Le Scotte, 53100 Siena, Italy
Br J Dermatol 152:679-84. 2005..CONCLUSIONS: We conclude that there are so far no digital dermoscopic criteria that can clearly distinguish dysplastic naevi from in situ melanomas... - Umbilical endometriosis in pregnancy: a case reportS Razzi
Department of Pediatrics, Obstetrics and Reproductive Medicine, Chair of Obstetrics and Gynecology, University of Siena, Italy
Gynecol Endocrinol 18:114-6. 2004..The patient was also examined at 24 weeks' gestation, after delivery and in the late postpartum period. No therapy was given and the lesion resolved spontaneously 2 months after the biopsy was taken... - Evaluation of tumour-infiltrating CD4+CD25+FOXP3+ regulatory T cells in human cutaneous benign and atypical naevi, melanomas and melanoma metastasesV Mourmouras
Department of Human Pathology and Oncology, Section of Pathological Anatomy, University of Siena, Siena 53100, Italy
Br J Dermatol 157:531-9. 2007..CD4+CD25+FOXP3+ regulatory T cells (Tregs) are thought to induce immunotolerance in melanoma. They have not yet been investigated in the entire spectrum of melanocytic cutaneous lesions within a tumour site... - Slow-growing melanoma: a dermoscopy follow-up studyG Argenziano
Department of Dermatology, Second University of Naples, Via S Pansini, 5 80131 Naples, Italy
Br J Dermatol 162:267-73. 2010..We initially evaluated five cases and found that none had baseline features suggestive of melanoma; excision was performed based on slight changes visible only in side-by-side comparisons of dermoscopic images... - Benign lymphoepithelial lesion associated with squamous cell carcinoma of the skin: an immunohistochemical and molecular genetic studyClelia Miracco
Institute of Pathological Anatomy and Histology, University of Siena, Siena, Italy
J Cutan Pathol 29:33-7. 2002..Skin lesions similar to LEL have been described in lymphomas, and are caused by neoplastic lymphocytes which infiltrate adnexal structures. To date, BLEL have not widely been recognized in the skin... - Different effects of interferon-alpha on melanoma cell lines: a study on telomerase reverse transcriptase, telomerase activity and apoptosisE Maellaro
Department of Pathophysiology and Experimental Medicine, University of Siena, Italy
Br J Dermatol 148:1115-24. 2003.... - Extracorporeal photochemotherapy in the treatment of eosinophilic fasciitisC Romano
Department of Dermatology, University of Siena, Italy
J Eur Acad Dermatol Venereol 17:10-3. 2003.... - A case of transient zinc deficiency in a breast-fed preterm infant successfully treated with oral zinc supplementation: review of zinc metabolism and related diseasesF Mandato
Clinical Medicine and Immunological Science Departemnt, Dermatology Section, Le Scotte University Hospital, Siena, Italy
G Ital Dermatol Venereol 144:729-34. 2009.... - Skin cancer day in Italy: method of referral to open access clinics and tumor prevalence in the examined populationPaolo Carli
Dipartimento di Scienze Dermatolog iche Via degli Alfani, 31, 50121 Firenze, Italy
Eur J Dermatol 13:76-9. 2003..Increased public awareness regarding skin cancer probably represents the main effect of this type of campaign... - The role of dermoscopy and digital dermoscopy analysis in the diagnosis of pigmented skin lesionsPietro Rubegni
Arch Dermatol 141:1444-6. 2005 - Predominant dermoscopic patterns observed among neviAlon Scope
Dermatology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10022, USA
J Cutan Med Surg 10:170-4. 2006..CONCLUSION: Individuals tend to have one to three predominant dermoscopic nevus global patterns... - Disseminated Mediterranean Kaposi sarcoma treated with low-dose recombinant interferon alfa-2aPietro Rubegni
J Am Acad Dermatol 48:148-9. 2003 - The spectrum of Spitz nevi: a clinicopathologic study of 83 casesGerardo Ferrara
Pathologic Anatomy Service, Gaetano Rummo General Hospital, Benevento, Italy
Arch Dermatol 141:1381-7. 2005..Asymmetry should be assessed using both dermoscopic and histopathologic analysis, and reliability in histopathologic diagnosis may be enhanced by the simultaneous evaluation of the corresponding dermoscopic images...