Gian Paolo Rossini

Summary

Affiliation: University of Modena and Reggio Emilia
Country: Italy

Publications

  1. ncbi request reprint Phycotoxins: chemistry, mechanisms of action and shellfish poisoning
    Gian Paolo Rossini
    Universita di Modena e Reggio Emilia, Dipartimento di Scienze Biomediche, Italy
    EXS 100:65-122. 2010
  2. ncbi request reprint Addendum to "A cytolytic assay for the measurement of palytoxin based on a cultured monolayer cell line" [Anal. Biochem. 374 (2008) 48-55]
    Mirella Bellocci
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Via Campi 287, 1 41100 Modena, Italy
    Anal Biochem 381:178. 2008
  3. doi request reprint Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells
    Mirella Bellocci
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Modena, Italy
    Toxicol Sci 117:109-21. 2010
  4. doi request reprint Azaspiracid-1 inhibits the maturation of cathepsin D in mammalian cells
    Gian Luca Sala
    Dipartimento di Scienze della Vita, Universita di Modena e Reggio Emilia, Via Campi 287, Modena, Italy
    Chem Res Toxicol 26:444-55. 2013
  5. ncbi request reprint Yessotoxin inhibits the complete degradation of E-cadherin
    Federica Callegari
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, via G Campi 287, I 41100 Modena, Italy
    Toxicology 244:133-44. 2008
  6. ncbi request reprint Yessotoxin induces the accumulation of altered E-cadherin dimers that are not part of adhesive structures in intact cells
    Giuseppe Ronzitti
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Via Campi 287, I 41100 Modena, Italy
    Toxicology 244:145-56. 2008
  7. doi request reprint Protein markers of algal toxin contamination in shellfish
    Giuseppe Ronzitti
    Universita di Modena e Reggio Emilia, Dipartimento di Scienze Biomediche, via G Campi 287, I 41100 Modena, Italy
    Toxicon 52:705-13. 2008
  8. doi request reprint Proteomic analysis reveals multiple patterns of response in cells exposed to a toxin mixture
    Gian Luca Sala
    Centro Interdisciplinare di Scienze e Tecnologie per la Qualità e Sicurezza degli Alimenti, Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, I 41100 Modena, Italy
    Chem Res Toxicol 22:1077-85. 2009
  9. doi request reprint The cytotoxic pathway triggered by palytoxin involves a change in the cellular pool of stress response proteins
    Gian Luca Sala
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, via G Campi 287, I 41125 Modena, Italy, Italy
    Chem Res Toxicol 22:2009-16. 2009
  10. doi request reprint Palytoxin induces cell lysis by priming a two-step process in mcf-7 cells
    Simone Prandi
    Dipartimento di Scienze Biomediche, Università di Modena e Reggio Emilia, Via Campi 287, I 41125 Modena, Italy
    Chem Res Toxicol 24:1283-96. 2011

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Phycotoxins: chemistry, mechanisms of action and shellfish poisoning
    Gian Paolo Rossini
    Universita di Modena e Reggio Emilia, Dipartimento di Scienze Biomediche, Italy
    EXS 100:65-122. 2010
    ..Based on recorded symptoms, the major poisonings recognized so far include paralytic, neurotoxic, amnesic, diarrheic shellfish poisonings, ciguatera, as well as palytoxin and azaspiracid poisonings...
  2. ncbi request reprint Addendum to "A cytolytic assay for the measurement of palytoxin based on a cultured monolayer cell line" [Anal. Biochem. 374 (2008) 48-55]
    Mirella Bellocci
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Via Campi 287, 1 41100 Modena, Italy
    Anal Biochem 381:178. 2008
  3. doi request reprint Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells
    Mirella Bellocci
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Modena, Italy
    Toxicol Sci 117:109-21. 2010
    ..The effects of AZA-1 on the E-cadherin system were confirmed in Caco-2 and Madin Darby canine kidney epithelial cell lines. We conclude that AZA-1 inhibits endocytosis of plasma membrane proteins in epithelial cells...
  4. doi request reprint Azaspiracid-1 inhibits the maturation of cathepsin D in mammalian cells
    Gian Luca Sala
    Dipartimento di Scienze della Vita, Universita di Modena e Reggio Emilia, Via Campi 287, Modena, Italy
    Chem Res Toxicol 26:444-55. 2013
    ..The data we obtained corroborated our hypothesis and provide a unified molecular frame for the mode of action of AZAs in animal models, involving a primary alteration of endocytic processes...
  5. ncbi request reprint Yessotoxin inhibits the complete degradation of E-cadherin
    Federica Callegari
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, via G Campi 287, I 41100 Modena, Italy
    Toxicology 244:133-44. 2008
    ..These findings reconcile the apparent contradictions of previous studies, showing that YTX does not promote E-cadherin degradation per se, but interferes with its complete disposal...
  6. ncbi request reprint Yessotoxin induces the accumulation of altered E-cadherin dimers that are not part of adhesive structures in intact cells
    Giuseppe Ronzitti
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Via Campi 287, I 41100 Modena, Italy
    Toxicology 244:145-56. 2008
    ..ECRA100 heterodimers that are not participating to cell adhesive structures but are located in other membranous fractions of intact cells...
  7. doi request reprint Protein markers of algal toxin contamination in shellfish
    Giuseppe Ronzitti
    Universita di Modena e Reggio Emilia, Dipartimento di Scienze Biomediche, via G Campi 287, I 41100 Modena, Italy
    Toxicon 52:705-13. 2008
    ....
  8. doi request reprint Proteomic analysis reveals multiple patterns of response in cells exposed to a toxin mixture
    Gian Luca Sala
    Centro Interdisciplinare di Scienze e Tecnologie per la Qualità e Sicurezza degli Alimenti, Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, I 41100 Modena, Italy
    Chem Res Toxicol 22:1077-85. 2009
    ..Multiple patterns of responses to the toxin mixture were recorded in the two sets, consisting of both independent and interacting actions, among which we detected synergistic, similar, and antagonistic effects...
  9. doi request reprint The cytotoxic pathway triggered by palytoxin involves a change in the cellular pool of stress response proteins
    Gian Luca Sala
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, via G Campi 287, I 41125 Modena, Italy, Italy
    Chem Res Toxicol 22:2009-16. 2009
    ....
  10. doi request reprint Palytoxin induces cell lysis by priming a two-step process in mcf-7 cells
    Simone Prandi
    Dipartimento di Scienze Biomediche, Università di Modena e Reggio Emilia, Via Campi 287, I 41125 Modena, Italy
    Chem Res Toxicol 24:1283-96. 2011
    ..A model of the two-step process of PlTX-induced cytolysis is presented...
  11. doi request reprint Palytoxin action on the Na(+),K(+)-ATPase and the disruption of ion equilibria in biological systems
    Gian Paolo Rossini
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, via G Campi 287, I 41125 Modena, Italy
    Toxicon 57:429-39. 2011
    ....
  12. doi request reprint The total activity of a mixture of okadaic acid-group compounds can be calculated by those of individual analogues in a phosphoprotein phosphatase 2A assay
    Clara Albano
    Universita di Modena e Reggio Emilia, Dipartimento di Scienze Biomediche, Via Campi 287, 1 41100 Modena, Italy
    Toxicon 53:631-7. 2009
    ..Our findings show that an additive model based on the use of toxicity equivalence factors of individual toxins is appropriate for the calculation of the total activity of multi-component mixtures of OA-group compounds in unknown samples...
  13. ncbi request reprint A cytolytic assay for the measurement of palytoxin based on a cultured monolayer cell line
    Mirella Bellocci
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, I 41100 Modena, Italy
    Anal Biochem 374:48-55. 2008
    ..We conclude that our cytolytic assay based on the use of MCF-7 cell monolayers is a viable alternative to animal-based methods for the determination of palytoxin and its congeners in contaminated materials...
  14. ncbi request reprint Azaspiracid-1 alters the E-cadherin pool in epithelial cells
    Giuseppe Ronzitti
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, I 41100 Modena, Italy
    Toxicol Sci 95:427-35. 2007
    ..The possibility that azaspiracids and YTXs might share their molecular mechanism(s) of action in defined biological settings should be considered...