Research Topics
Species | Giulio RossiSummaryAffiliation: University of Modena and Reggio Emilia Country: Italy Publications
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Detail Information
Publications
Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: a clinicopathologic and immunohistochemical study of 75 casesGiulio Rossi
Section of Pathology, University of Modeno and Reggio Emilia, Via del Pozzo, 71 41100 Modena, Italy
Am J Surg Pathol 27:311-24. 2003....
Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lungGiulio Rossi
Integrated Department of Diagnostic and Laboratory Services and Legal Medicine, Section of Pathologic Anatomy, Respiratory Disease Clinic, University of Modena and Reggio Emilia, Via del Pozzo, 71 41100, Modena, Italy
J Clin Oncol 23:8774-85. 2005..Little is known about the optimal therapy of LCNEC and the possible therapeutic molecular targets...
Atypical carcinoid with prominent mucinous stroma: a hitherto unreported variant of pulmonary neuroendocrine tumorNazarena Nannini
Section of Pathologic Anatomy, Azienda Ospedaliera Universitaria Policlinico, Via del Pozzo, 71 41100, Modena, Italy
Endocr Pathol 21:120-4. 2010..The lack of TTF-1 expression and the positive staining with hormonal receptors made the diagnosis very challenging. Differential diagnosis with other primary and metastatic mucin-rich tumors is also discussed...
Primary mixed adenocarcinoma and small cell carcinoma of the appendix: a clinicopathologic, immunohistochemical, and molecular study of a hitherto unreported tumorGiulio Rossi
Department of Pathologic Anatomy and Legal Medicine, Section of Pathology, University of Modena and Reggio Emilia, Italy
Am J Surg Pathol 28:1233-9. 2004..Clinical and molecular findings led us to consider this lesion as a clonal tumor in which the endocrine component seems to derive from a progressive differentiation of the adenocarcinoma following a glandular-to-endocrine sequence...
EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitorsGiuliana Sartori
Section of Pathologic Anatomy, Azienda Ospedaliero Universitaria Policlinico di Modena, Via del Pozzo, 71 41100 Modena, Italy
Am J Clin Pathol 131:478-89. 2009..K-ras mutations, significantly associated with the mucin-secreting type of adenocarcinoma, consistently predict lack of response in white patients...
Kit expression in small cell carcinomas of the lung: effects of chemotherapyGiulio Rossi
Department of Pathologic Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Bologna, Italy
Mod Pathol 16:1041-7. 2003....
Bronchial typical carcinoid tumorsUliano Morandi
Division of Thoracic Surgery, Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia, Modena, Italy
Semin Thorac Cardiovasc Surg 18:191-8. 2006..N-status and type of resection seem not to affect prognosis. Local relapse can be treated successfully with surgery, whereas distant metastases have a poor prognosis even after chemotherapy...
Superficial papillary urothelial carcinomas in young and elderly patients: a comparative studyMario Migaldi
Department of Pathological Anatomy and Legal Medicine, Section of Pathological Anatomy, University of Modena and Reggio Emilia, Via del Pozzo 77, 41100 Modena, Italy
BJU Int 94:311-6. 2004..Proliferative activity and cyclin D1 expression levels were of prognostic significance for the risk of recurrence in these patients...
Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expressionGiulio Rossi
Department of Pathologic Anatomy and Forensic Medicine, University of Modena and Reggio Emilia, Modena, Italy
Am J Surg Pathol 28:442-52. 2004..Since goblet cell-type MC strongly stains with CDX2, MUC2, and CK20, differential diagnosis with metastatic colorectal carcinoma is very challenging and requires appropriate clinical correlation...
Pleural malignant solitary fibrous tumor with sarcomatous overgrowth showing PDGFRbeta mutationGiulio Rossi
Section of Pathologic Anatomy, University of Modena and Reggio Emilia, Modena, Italy
Chest 130:581-3. 2006..The involvement of the PDGFRbeta gene in SFT is compatible with a pericytic derivation, also supporting a possible role of this tyrosine kinase in malignant transformation and in the adoption of novel molecular therapies...
Gastrointestinal stromal tumor and other primary metachronous or synchronous neoplasms as a suspicion criterion for syndromic settingGiovanni Ponti
Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy
Oncol Rep 23:437-44. 2010..In particular, syndromic or familial settings have to be suspected in the presence of neurofibroma or lung chordoma in C-KIT and PDGFRA negative GIST patients...
Does mesoappendix infiltration predict a worse prognosis in incidental neuroendocrine tumors of the appendix? A clinicopathologic and immunohistochemical study of 15 casesGiulio Rossi
Department of Pathologic Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Via del Pozzo, 71, 41100 Modena, Italy
Am J Clin Pathol 120:706-11. 2003..Tumors less than 2 cm, even with mesoappendiceal infiltration, have an excellent prognosis, and simple appendectomy seems to be the appropriate therapeutic approach...
Does HPV play a role in the etiopathogenesis of ameloblastoma? An immunohistochemical, in situ hybridization and polymerase chain reaction study of 18 cases using laser capture microdissectionMario Migaldi
Department of Pathologic Anatomy and Legal Medicine, Section of Pathology, University of Modena and Reggio Emilia, 41100 Modena, Italy
Mod Pathol 18:283-9. 2005..The search for HPV 6 and 11 in the same specimens was also negative. In conclusion, our data do not support an etiopathogenetic evidence for HPV in ameloblastoma...
Atypical lipomatous tumour (lipoma-like well-differentiated liposarcoma) arising in a pulmonary hamartoma and clinically presenting with pneumothoraxGiulio Rossi
Department of Pathological Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Via del Pozzo, 71 41100, Modena, Italy
Lung Cancer 39:103-6. 2003..This case represents an exceedingly rare example of an histologically malignant change in PH and bears a close clinicopathologic resemblance to atypical lipomatous tumours of soft tissues...
Pulmonary hamartoma associated with typical carcinoid/tumorletAlberto Cavazza
Virchows Arch 449:392-3. 2006
Exclusive intrapulmonary lepidic growth of a malignant pleural mesothelioma presenting with pneumothorax and involving the peritoneumGiulio Rossi
Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy
Int J Surg Pathol 14:234-7. 2006..The morphologic clues leading to the correct diagnosis of mesothelioma with prominent intrapulmonary growth are briefly discussed...
Paraffinoma and carcinoid tumorlet: a hitherto unreported association mimicking lung cancerChristian Casali
Department of General Surgery and Surgical Specialties, Azienda Ospedaliera-Universitaria Policlinico, Modena, Italy
J Thorac Oncol 2:1052-3. 2007
Mucin-rich tumors of the lungGiulio Rossi
Am J Clin Pathol 127:473-4; author reply 474. 2007
[Primary cardiac sarcoma. Description of a case]Silvia Tremosini
Divisione di Medicina Interna II, Dipartimento di Medicine e Specialità Mediche, Universita degli Studi di Modena e Reggio Emilia, Modena
G Ital Cardiol (Rome) 8:196-200. 2007..This case is an example of a primary cardiac tumor that causes relative myocardial sufferance both by infiltration and by limitation of normal heart diastolic function...
Microsatellite and EGFR, HER2 and K-RAS analyses in sclerosing hemangioma of the lungGiuliana Sartori
Section of Pathologic Anatomy, Azienda Policlinico, Via del Pozzo 71, 41100 Modena, Italy
Am J Surg Pathol 31:1512-20. 2007..Microsatellite alterations identified in cuboidal and polygonal cells further confirm the clonal and neoplastic nature of both components of SH...
Pleuro-pulmonary solitary fibrous tumors: a clinicopathologic, immunohistochemical, and molecular study of 88 cases confirming the prognostic value of de Perrot staging system and p53 expression, and evaluating the role of c-kit, BRAF, PDGFRs (alpha/beta)Laura Schirosi
Section of Pathologic Anatomy, Azienda Ospedaliera Universitaria Policlinico, Modena, Italy
Am J Surg Pathol 32:1627-42. 2008....
Expression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinomaAlessandro Sgambato
Centro di Ricerche Oncologiche Giovanni XXIII Istituto di Patologia General, Universita Cattolica del Sacro Cuore, Rome, Italy
Cancer Biol Ther 6:1840-6. 2007....
A subset of lung adenocarcinomas and atypical adenomatous hyperplasia-associated foci are genotypically related: an EGFR, HER2, and K-ras mutational analysisGiuliana Sartori
Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy
Am J Clin Pathol 129:202-10. 2008..All cases were wild-type for HER2. Mutations of EGFR and K-ras genes represent an early event in lung adenocarcinomagenesis, and AAH convincingly seems to be a precursor lesion in a subset of cases of adenocarcinoma...
Pulmonary strongyloidiasis mimicking cancer symptoms: a case of hyperinfection in a patient with metastatic lung cancerFederica Bertolini
Department of Medical Oncology, Policlinico di Modena, Modena, Italy
Am J Clin Oncol 31:308-9. 2008
CDX2 expression and lung cancerGiulio Rossi
Appl Immunohistochem Mol Morphol 14:249-50. 2006
Alveolar adenoma of the lung: a clinicopathologic, immunohistochemical, and molecular study of an unusual caseAlberto Cavazza
Department of Pathology, S. Maria Nuova Hospital, Reggio Emilia, Italy
Int J Surg Pathol 12:155-9. 2004....
The prognostic role of c-kit protein expression in resected large cell neuroendocrine carcinoma of the lungChristian Casali
Department of Surgical and Medical Specialties, University of Modena and Reggio Emilia, Modena, Italy
Ann Thorac Surg 77:247-52; discussion 252-3. 2004..The c-kit protein is frequently expressed in this neoplasia and its expression represents a negative prognostic factor. This immunohistochemical marker may represent the basic rationale to select LCNEC for novel targeted therapy...
TTF-1, cytokeratin 7, 34betaE12, and CD56/NCAM immunostaining in the subclassification of large cell carcinomas of the lungGiulio Rossi
University of Modena and Reggio Emilia, Modena, Italy
Am J Clin Pathol 122:884-93. 2004....
Bronchioloalveolar carcinoma with nodular ("morule-like") featuresAdele Fornelli
Virchows Arch 442:407-8. 2003
Expression of thyroid transcription factor-1 in the spectrum of neuroendocrine cell lung proliferations with special interest in carcinoidsNathalie Sturm
Laboratoire de Pathologie Cellulaire, Service de Chirurgie Thoracique and the Lung Cancer Research Group, INSERM 9924, Centre Hospitalo Universitaire Albert Michallon, Grenoble, France
Hum Pathol 33:175-82. 2002..This challenges the concept of a spectrum of NE proliferations and tumors and lends credence to the alternative hypothesis of a common derivation for SCLC and non-SCLC including LCNEC, with carcinoids deriving from a different stem cell...
Prevalence and prognostic significance of microsatellite alterations in young patients with bladder cancerMario Migaldi
Dipartimento Misto di Anatomia Patologica e di Medicina Legale, Sezione di Anatomia Patologica, University of Modena and Reggio Emilia, Modena, Italy
Mod Pathol 18:1176-86. 2005..02) in a univariate analysis. These findings demonstrate that microsatellite alterations are frequent and early events and might have a prognostic significance in bladder cancers arising at young age...
Prognostic factors in surgically resected N2 non-small cell lung cancer: the importance of patterns of mediastinal lymph nodes metastasesChristian Casali
Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41100 Modena, Italy
Eur J Cardiothorac Surg 28:33-8. 2005..CONCLUSIONS: Clinical N2 status, number of lymph nodes levels involved and specific patterns of lymphatic spread identify homogenous subgroups of patients that can be proposed for different therapeutic strategies...
Dystroglycan expression is frequently reduced in human breast and colon cancers and is associated with tumor progressionAlessandro Sgambato
Centro di Ricerche Oncologiche Giovanni XXIII, Istituto di Patologia Generale, Catholic University, Rome, Italy
Am J Pathol 162:849-60. 2003..013 by log-rank test) in an univariate analysis. These data indicate that DG expression is frequently lost in human malignancies and suggest that this glycoprotein might play an important role in human tumor development and progression...
Mismatch repair system (MMR) status correlates with response and survival in non-small cell lung cancer (NSCLC) patientsMario Scartozzi
Clinica di Oncologia Medica, , Ancona, Italy
Lung Cancer 53:103-9. 2006..031) and 10 months versus 9 months for hMSH2 (p=0.8330). Both the difference in response rate and in median survival observed according to MMR status seem to confirm what has been suggested by preclinical studies...
Assessment of Aspergillus-specific T cells for diagnosis of invasive aspergillosis in a leukemic child with liver lesions mimicking hepatosplenic candidiasisLeonardo Potenza
Department of Oncology and Hematology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, 41100 Modena, Italy
Clin Vaccine Immunol 15:1625-8. 2008..The ELISPOT assay holds promise for diagnosing pediatric IA...
Traumatic neuroma of the bronchi: bronchoscopy and histology of a hitherto unreported lesionGiulio Rossi
Am J Surg Pathol 32:640-1. 2008
Lymphangioleiomyomatosis associated with pulmonary metastasis from an occult papillary carcinoma of the thyroid: report of a case occurring in a patient without tuberous sclerosisAlberto Cavazza
Department of Pathology, S Maria Nuova Hospital, Reggio Emilia, Italy
Pathol Res Pract 198:825-8. 2002..The main histologic differential diagnosis and the possible correlation between lymphangioleiomyomatosis and thyroid diseases are briefly discussed...
Incidence and clinicopathologic features of gastrointestinal stromal tumors. A population-based studyClaudia Mucciarini
Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy
BMC Cancer 7:230. 2007..This study examined the incidence of GIST in the province of Modena, including pathologic features and clinical outcome...
Placental transmogrification of the lung: clinicopathologic, immunohistochemical and molecular study of two cases, with particular emphasis on the interstitial clear cellsAlberto Cavazza
Operative Unit of Pathology, S. Maria Nuova Hospital, Reggio Emilia, Italy
Hum Pathol 35:517-21. 2004..This report presents a histological, immunohistochemical, ultrastructural and molecular study of these peculiar cells, together with a review of the literature...
Occurrence of pleural masses in a chronic pleural pyothoraxAlessandro Marchioni
Operative Unit of Pulmonology, Civic Hospital of Mirandola, Modena (Italy
J Thorac Oncol 2:968-9. 2007
EGFR mutations and sensitivity to gefitinibGiulio Rossi
N Engl J Med 351:1260-1; author reply 1260-1. 2004
Unusual pathogenesis of spontaneous pneumothorax secondary to Wegener's granulomatosisErica Storelli
Department of General Surgery and Surgical Specialties, Division of Thoracic Surgery, University of Modena and Reggio Emilia, Modena, Italy
Ann Thorac Surg 84:288-90. 2007..Histologic findings did not reveal any necrotizing granulomatous vasculitis, but only subpleural fibrous tissue. We hypothesize that pneumothorax could be related to the subpleural fibrous retraction induced by immunosuppressive therapy...
Mucinous cells in type 1 pulmonary congenital cystic adenomatoid malformation as mucinous bronchioloalveolar carcinoma precursorsSylvie Lantuejoul
Department of Pathology and Lung Cancer Research Group, INSERM U578, CHU A Michallon, Grenoble, France
Am J Surg Pathol 31:961-9. 2007..Moreover, the high frequency of K-ras mutation and LOH and/or microsatellite alterations at p16(INK4) locus presented by these mucinous cells justifies their consideration as BAC precursors...
Laparoscopic approach of gastric gastrointestinal stromal tumors (GISTs): is it still a courageous choice? Report of two casesRoberta Gelmini
Department of Surgery, University of Modena e Reggio Emilia, Italy
Surg Laparosc Endosc Percutan Tech 17:133-7. 2007..Here we report 2 cases of GIST surgically resected using a videolaparoscopic approach and discuss the efficacy of this technique in selected patients...
Primary lung cancer presenting with gastrointestinal tract involvement: clinicopathologic and immunohistochemical features in a series of 18 consecutive casesGiulio Rossi
Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy
J Thorac Oncol 2:115-20. 2007..The clinicopathologic characteristics of the largest series of lung carcinomas initially presenting with GI involvement were described, focusing on differential diagnosis and therapeutic options...
Cutaneous metastases as the first manifestation of pleural malignant mesotheliomaAntonio Maiorana
J Am Acad Dermatol 54:363-5. 2006
Does primary pulmonary choriocarcinoma really exist?Giulio Rossi
Chest 123:313. 2003
