Giulio Rossi

Summary

Affiliation: University of Modena and Reggio Emilia
Country: Italy

Publications

  1. ncbi Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: a clinicopathologic and immunohistochemical study of 75 cases
    Giulio Rossi
    Section of Pathology, University of Modeno and Reggio Emilia, Via del Pozzo, 71 41100 Modena, Italy
    Am J Surg Pathol 27:311-24. 2003
  2. ncbi Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lung
    Giulio Rossi
    Integrated Department of Diagnostic and Laboratory Services and Legal Medicine, Section of Pathologic Anatomy, Respiratory Disease Clinic, University of Modena and Reggio Emilia, Via del Pozzo, 71 41100, Modena, Italy
    J Clin Oncol 23:8774-85. 2005
  3. doi Atypical carcinoid with prominent mucinous stroma: a hitherto unreported variant of pulmonary neuroendocrine tumor
    Nazarena Nannini
    Section of Pathologic Anatomy, Azienda Ospedaliera Universitaria Policlinico, Via del Pozzo, 71 41100, Modena, Italy
    Endocr Pathol 21:120-4. 2010
  4. ncbi Primary mixed adenocarcinoma and small cell carcinoma of the appendix: a clinicopathologic, immunohistochemical, and molecular study of a hitherto unreported tumor
    Giulio Rossi
    Department of Pathologic Anatomy and Legal Medicine, Section of Pathology, University of Modena and Reggio Emilia, Italy
    Am J Surg Pathol 28:1233-9. 2004
  5. doi EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors
    Giuliana Sartori
    Section of Pathologic Anatomy, Azienda Ospedaliero Universitaria Policlinico di Modena, Via del Pozzo, 71 41100 Modena, Italy
    Am J Clin Pathol 131:478-89. 2009
  6. ncbi Kit expression in small cell carcinomas of the lung: effects of chemotherapy
    Giulio Rossi
    Department of Pathologic Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Bologna, Italy
    Mod Pathol 16:1041-7. 2003
  7. ncbi Bronchial typical carcinoid tumors
    Uliano Morandi
    Division of Thoracic Surgery, Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia, Modena, Italy
    Semin Thorac Cardiovasc Surg 18:191-8. 2006
  8. ncbi Superficial papillary urothelial carcinomas in young and elderly patients: a comparative study
    Mario Migaldi
    Department of Pathological Anatomy and Legal Medicine, Section of Pathological Anatomy, University of Modena and Reggio Emilia, Via del Pozzo 77, 41100 Modena, Italy
    BJU Int 94:311-6. 2004
  9. ncbi Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression
    Giulio Rossi
    Department of Pathologic Anatomy and Forensic Medicine, University of Modena and Reggio Emilia, Modena, Italy
    Am J Surg Pathol 28:442-52. 2004
  10. ncbi Pleural malignant solitary fibrous tumor with sarcomatous overgrowth showing PDGFRbeta mutation
    Giulio Rossi
    Section of Pathologic Anatomy, University of Modena and Reggio Emilia, Modena, Italy
    Chest 130:581-3. 2006

Collaborators

Detail Information

Publications47

  1. ncbi Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: a clinicopathologic and immunohistochemical study of 75 cases
    Giulio Rossi
    Section of Pathology, University of Modeno and Reggio Emilia, Via del Pozzo, 71 41100 Modena, Italy
    Am J Surg Pathol 27:311-24. 2003
    ....
  2. ncbi Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lung
    Giulio Rossi
    Integrated Department of Diagnostic and Laboratory Services and Legal Medicine, Section of Pathologic Anatomy, Respiratory Disease Clinic, University of Modena and Reggio Emilia, Via del Pozzo, 71 41100, Modena, Italy
    J Clin Oncol 23:8774-85. 2005
    ..Little is known about the optimal therapy of LCNEC and the possible therapeutic molecular targets...
  3. doi Atypical carcinoid with prominent mucinous stroma: a hitherto unreported variant of pulmonary neuroendocrine tumor
    Nazarena Nannini
    Section of Pathologic Anatomy, Azienda Ospedaliera Universitaria Policlinico, Via del Pozzo, 71 41100, Modena, Italy
    Endocr Pathol 21:120-4. 2010
    ..The lack of TTF-1 expression and the positive staining with hormonal receptors made the diagnosis very challenging. Differential diagnosis with other primary and metastatic mucin-rich tumors is also discussed...
  4. ncbi Primary mixed adenocarcinoma and small cell carcinoma of the appendix: a clinicopathologic, immunohistochemical, and molecular study of a hitherto unreported tumor
    Giulio Rossi
    Department of Pathologic Anatomy and Legal Medicine, Section of Pathology, University of Modena and Reggio Emilia, Italy
    Am J Surg Pathol 28:1233-9. 2004
    ..Clinical and molecular findings led us to consider this lesion as a clonal tumor in which the endocrine component seems to derive from a progressive differentiation of the adenocarcinoma following a glandular-to-endocrine sequence...
  5. doi EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors
    Giuliana Sartori
    Section of Pathologic Anatomy, Azienda Ospedaliero Universitaria Policlinico di Modena, Via del Pozzo, 71 41100 Modena, Italy
    Am J Clin Pathol 131:478-89. 2009
    ..K-ras mutations, significantly associated with the mucin-secreting type of adenocarcinoma, consistently predict lack of response in white patients...
  6. ncbi Kit expression in small cell carcinomas of the lung: effects of chemotherapy
    Giulio Rossi
    Department of Pathologic Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Bologna, Italy
    Mod Pathol 16:1041-7. 2003
    ....
  7. ncbi Bronchial typical carcinoid tumors
    Uliano Morandi
    Division of Thoracic Surgery, Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia, Modena, Italy
    Semin Thorac Cardiovasc Surg 18:191-8. 2006
    ..N-status and type of resection seem not to affect prognosis. Local relapse can be treated successfully with surgery, whereas distant metastases have a poor prognosis even after chemotherapy...
  8. ncbi Superficial papillary urothelial carcinomas in young and elderly patients: a comparative study
    Mario Migaldi
    Department of Pathological Anatomy and Legal Medicine, Section of Pathological Anatomy, University of Modena and Reggio Emilia, Via del Pozzo 77, 41100 Modena, Italy
    BJU Int 94:311-6. 2004
    ....
  9. ncbi Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression
    Giulio Rossi
    Department of Pathologic Anatomy and Forensic Medicine, University of Modena and Reggio Emilia, Modena, Italy
    Am J Surg Pathol 28:442-52. 2004
    ..Since goblet cell-type MC strongly stains with CDX2, MUC2, and CK20, differential diagnosis with metastatic colorectal carcinoma is very challenging and requires appropriate clinical correlation...
  10. ncbi Pleural malignant solitary fibrous tumor with sarcomatous overgrowth showing PDGFRbeta mutation
    Giulio Rossi
    Section of Pathologic Anatomy, University of Modena and Reggio Emilia, Modena, Italy
    Chest 130:581-3. 2006
    ..The involvement of the PDGFRbeta gene in SFT is compatible with a pericytic derivation, also supporting a possible role of this tyrosine kinase in malignant transformation and in the adoption of novel molecular therapies...
  11. ncbi Gastrointestinal stromal tumor and other primary metachronous or synchronous neoplasms as a suspicion criterion for syndromic setting
    Giovanni Ponti
    Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy
    Oncol Rep 23:437-44. 2010
    ..In particular, syndromic or familial settings have to be suspected in the presence of neurofibroma or lung chordoma in C-KIT and PDGFRA negative GIST patients...
  12. ncbi Does mesoappendix infiltration predict a worse prognosis in incidental neuroendocrine tumors of the appendix? A clinicopathologic and immunohistochemical study of 15 cases
    Giulio Rossi
    Department of Pathologic Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Via del Pozzo, 71, 41100 Modena, Italy
    Am J Clin Pathol 120:706-11. 2003
    ..Tumors less than 2 cm, even with mesoappendiceal infiltration, have an excellent prognosis, and simple appendectomy seems to be the appropriate therapeutic approach...
  13. ncbi Does HPV play a role in the etiopathogenesis of ameloblastoma? An immunohistochemical, in situ hybridization and polymerase chain reaction study of 18 cases using laser capture microdissection
    Mario Migaldi
    Department of Pathologic Anatomy and Legal Medicine, Section of Pathology, University of Modena and Reggio Emilia, 41100 Modena, Italy
    Mod Pathol 18:283-9. 2005
    ..The search for HPV 6 and 11 in the same specimens was also negative. In conclusion, our data do not support an etiopathogenetic evidence for HPV in ameloblastoma...
  14. ncbi Atypical lipomatous tumour (lipoma-like well-differentiated liposarcoma) arising in a pulmonary hamartoma and clinically presenting with pneumothorax
    Giulio Rossi
    Department of Pathological Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Via del Pozzo, 71 41100, Modena, Italy
    Lung Cancer 39:103-6. 2003
    ..This case represents an exceedingly rare example of an histologically malignant change in PH and bears a close clinicopathologic resemblance to atypical lipomatous tumours of soft tissues...
  15. ncbi Pulmonary hamartoma associated with typical carcinoid/tumorlet
    Alberto Cavazza
    Virchows Arch 449:392-3. 2006
  16. ncbi Exclusive intrapulmonary lepidic growth of a malignant pleural mesothelioma presenting with pneumothorax and involving the peritoneum
    Giulio Rossi
    Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy
    Int J Surg Pathol 14:234-7. 2006
    ..The morphologic clues leading to the correct diagnosis of mesothelioma with prominent intrapulmonary growth are briefly discussed...
  17. ncbi Paraffinoma and carcinoid tumorlet: a hitherto unreported association mimicking lung cancer
    Christian Casali
    Department of General Surgery and Surgical Specialties, Azienda Ospedaliera Universitaria Policlinico, Modena, Italy
    J Thorac Oncol 2:1052-3. 2007
  18. ncbi Mucin-rich tumors of the lung
    Giulio Rossi
    Am J Clin Pathol 127:473-4; author reply 474. 2007
  19. ncbi [Primary cardiac sarcoma. Description of a case]
    Silvia Tremosini
    Divisione di Medicina Interna II, Dipartimento di Medicine e Specialità Mediche, Universita degli Studi di Modena e Reggio Emilia, Modena
    G Ital Cardiol (Rome) 8:196-200. 2007
    ..This case is an example of a primary cardiac tumor that causes relative myocardial sufferance both by infiltration and by limitation of normal heart diastolic function...
  20. ncbi Microsatellite and EGFR, HER2 and K-RAS analyses in sclerosing hemangioma of the lung
    Giuliana Sartori
    Section of Pathologic Anatomy, Azienda Policlinico, Via del Pozzo 71, 41100 Modena, Italy
    Am J Surg Pathol 31:1512-20. 2007
    ..Microsatellite alterations identified in cuboidal and polygonal cells further confirm the clonal and neoplastic nature of both components of SH...
  21. doi Pleuro-pulmonary solitary fibrous tumors: a clinicopathologic, immunohistochemical, and molecular study of 88 cases confirming the prognostic value of de Perrot staging system and p53 expression, and evaluating the role of c-kit, BRAF, PDGFRs (alpha/beta)
    Laura Schirosi
    Section of Pathologic Anatomy, Azienda Ospedaliera Universitaria Policlinico, Modena, Italy
    Am J Surg Pathol 32:1627-42. 2008
    ....
  22. ncbi Expression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinoma
    Alessandro Sgambato
    Centro di Ricerche Oncologiche Giovanni XXIII Istituto di Patologia General, Universita Cattolica del Sacro Cuore, Rome, Italy
    Cancer Biol Ther 6:1840-6. 2007
    ....
  23. doi A subset of lung adenocarcinomas and atypical adenomatous hyperplasia-associated foci are genotypically related: an EGFR, HER2, and K-ras mutational analysis
    Giuliana Sartori
    Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy
    Am J Clin Pathol 129:202-10. 2008
    ..All cases were wild-type for HER2. Mutations of EGFR and K-ras genes represent an early event in lung adenocarcinomagenesis, and AAH convincingly seems to be a precursor lesion in a subset of cases of adenocarcinoma...
  24. doi Pulmonary strongyloidiasis mimicking cancer symptoms: a case of hyperinfection in a patient with metastatic lung cancer
    Federica Bertolini
    Department of Medical Oncology, Policlinico di Modena, Modena, Italy
    Am J Clin Oncol 31:308-9. 2008
  25. ncbi CDX2 expression and lung cancer
    Giulio Rossi
    Appl Immunohistochem Mol Morphol 14:249-50. 2006
  26. ncbi Alveolar adenoma of the lung: a clinicopathologic, immunohistochemical, and molecular study of an unusual case
    Alberto Cavazza
    Department of Pathology, S Maria Nuova Hospital, Reggio Emilia, Italy
    Int J Surg Pathol 12:155-9. 2004
    ....
  27. ncbi The prognostic role of c-kit protein expression in resected large cell neuroendocrine carcinoma of the lung
    Christian Casali
    Department of Surgical and Medical Specialties, University of Modena and Reggio Emilia, Modena, Italy
    Ann Thorac Surg 77:247-52; discussion 252-3. 2004
    ..Because c-kit protein overexpression has been recently reported as a negative prognostic factor in SCLC we investigated its expression and prognostic value in a series of LCNEC...
  28. ncbi TTF-1, cytokeratin 7, 34betaE12, and CD56/NCAM immunostaining in the subclassification of large cell carcinomas of the lung
    Giulio Rossi
    University of Modena and Reggio Emilia, Modena, Italy
    Am J Clin Pathol 122:884-93. 2004
    ....
  29. ncbi Bronchioloalveolar carcinoma with nodular ("morule-like") features
    Adele Fornelli
    Virchows Arch 442:407-8. 2003
  30. ncbi Expression of thyroid transcription factor-1 in the spectrum of neuroendocrine cell lung proliferations with special interest in carcinoids
    Nathalie Sturm
    Laboratoire de Pathologie Cellulaire, Service de Chirurgie Thoracique and the Lung Cancer Research Group, INSERM 9924, Centre Hospitalo Universitaire Albert Michallon, Grenoble, France
    Hum Pathol 33:175-82. 2002
    ..This challenges the concept of a spectrum of NE proliferations and tumors and lends credence to the alternative hypothesis of a common derivation for SCLC and non-SCLC including LCNEC, with carcinoids deriving from a different stem cell...
  31. ncbi Prevalence and prognostic significance of microsatellite alterations in young patients with bladder cancer
    Mario Migaldi
    Dipartimento Misto di Anatomia Patologica e di Medicina Legale, Sezione di Anatomia Patologica, University of Modena and Reggio Emilia, Modena, Italy
    Mod Pathol 18:1176-86. 2005
    ..02) in a univariate analysis. These findings demonstrate that microsatellite alterations are frequent and early events and might have a prognostic significance in bladder cancers arising at young age...
  32. ncbi Prognostic factors in surgically resected N2 non-small cell lung cancer: the importance of patterns of mediastinal lymph nodes metastases
    Christian Casali
    Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41100 Modena, Italy
    Eur J Cardiothorac Surg 28:33-8. 2005
    ..Indication and timing of surgery remain controversial. The present study investigates the prognostic factors, in order to identify homogenous subgroups of patients...
  33. pmc Dystroglycan expression is frequently reduced in human breast and colon cancers and is associated with tumor progression
    Alessandro Sgambato
    Centro di Ricerche Oncologiche Giovanni XXIII, Istituto di Patologia Generale, Catholic University, Rome, Italy
    Am J Pathol 162:849-60. 2003
    ..013 by log-rank test) in an univariate analysis. These data indicate that DG expression is frequently lost in human malignancies and suggest that this glycoprotein might play an important role in human tumor development and progression...
  34. ncbi Mismatch repair system (MMR) status correlates with response and survival in non-small cell lung cancer (NSCLC) patients
    Mario Scartozzi
    Clinica di Oncologia Medica, Azienda Ospedaliero Universitaria Ospedali Riuniti e Università Politecnica delle Marche, Ancona, Italy
    Lung Cancer 53:103-9. 2006
    ..031) and 10 months versus 9 months for hMSH2 (p=0.8330). Both the difference in response rate and in median survival observed according to MMR status seem to confirm what has been suggested by preclinical studies...
  35. pmc Assessment of Aspergillus-specific T cells for diagnosis of invasive aspergillosis in a leukemic child with liver lesions mimicking hepatosplenic candidiasis
    Leonardo Potenza
    Department of Oncology and Hematology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, 41100 Modena, Italy
    Clin Vaccine Immunol 15:1625-8. 2008
    ..The ELISPOT assay holds promise for diagnosing pediatric IA...
  36. doi Traumatic neuroma of the bronchi: bronchoscopy and histology of a hitherto unreported lesion
    Giulio Rossi
    Am J Surg Pathol 32:640-1. 2008
  37. ncbi Lymphangioleiomyomatosis associated with pulmonary metastasis from an occult papillary carcinoma of the thyroid: report of a case occurring in a patient without tuberous sclerosis
    Alberto Cavazza
    Department of Pathology, S Maria Nuova Hospital, Reggio Emilia, Italy
    Pathol Res Pract 198:825-8. 2002
    ..The main histologic differential diagnosis and the possible correlation between lymphangioleiomyomatosis and thyroid diseases are briefly discussed...
  38. pmc Incidence and clinicopathologic features of gastrointestinal stromal tumors. A population-based study
    Claudia Mucciarini
    Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy
    BMC Cancer 7:230. 2007
    ..This study examined the incidence of GIST in the province of Modena, including pathologic features and clinical outcome...
  39. ncbi Placental transmogrification of the lung: clinicopathologic, immunohistochemical and molecular study of two cases, with particular emphasis on the interstitial clear cells
    Alberto Cavazza
    Operative Unit of Pathology, S Maria Nuova Hospital, Reggio Emilia, Italy
    Hum Pathol 35:517-21. 2004
    ..This report presents a histological, immunohistochemical, ultrastructural and molecular study of these peculiar cells, together with a review of the literature...
  40. ncbi Occurrence of pleural masses in a chronic pleural pyothorax
    Alessandro Marchioni
    Operative Unit of Pulmonology, Civic Hospital of Mirandola, Modena Italy
    J Thorac Oncol 2:968-9. 2007
  41. ncbi EGFR mutations and sensitivity to gefitinib
    Giulio Rossi
    N Engl J Med 351:1260-1; author reply 1260-1. 2004
  42. ncbi Unusual pathogenesis of spontaneous pneumothorax secondary to Wegener's granulomatosis
    Erica Storelli
    Department of General Surgery and Surgical Specialties, Division of Thoracic Surgery, University of Modena and Reggio Emilia, Modena, Italy
    Ann Thorac Surg 84:288-90. 2007
    ..Histologic findings did not reveal any necrotizing granulomatous vasculitis, but only subpleural fibrous tissue. We hypothesize that pneumothorax could be related to the subpleural fibrous retraction induced by immunosuppressive therapy...
  43. ncbi Mucinous cells in type 1 pulmonary congenital cystic adenomatoid malformation as mucinous bronchioloalveolar carcinoma precursors
    Sylvie Lantuejoul
    Department of Pathology and Lung Cancer Research Group, INSERM U578, CHU A Michallon, Grenoble, France
    Am J Surg Pathol 31:961-9. 2007
    ..Moreover, the high frequency of K-ras mutation and LOH and/or microsatellite alterations at p16(INK4) locus presented by these mucinous cells justifies their consideration as BAC precursors...
  44. ncbi Laparoscopic approach of gastric gastrointestinal stromal tumors (GISTs): is it still a courageous choice? Report of two cases
    Roberta Gelmini
    Department of Surgery, University of Modena e Reggio Emilia, Italy
    Surg Laparosc Endosc Percutan Tech 17:133-7. 2007
    ..Here we report 2 cases of GIST surgically resected using a videolaparoscopic approach and discuss the efficacy of this technique in selected patients...
  45. ncbi Primary lung cancer presenting with gastrointestinal tract involvement: clinicopathologic and immunohistochemical features in a series of 18 consecutive cases
    Giulio Rossi
    Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy
    J Thorac Oncol 2:115-20. 2007
    ..The clinicopathologic characteristics of the largest series of lung carcinomas initially presenting with GI involvement were described, focusing on differential diagnosis and therapeutic options...
  46. ncbi Cutaneous metastases as the first manifestation of pleural malignant mesothelioma
    Antonio Maiorana
    J Am Acad Dermatol 54:363-5. 2006
  47. ncbi Does primary pulmonary choriocarcinoma really exist?
    Giulio Rossi
    Chest 123:313. 2003