Daniela Rossi

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. doi request reprint Focal degeneration of astrocytes in amyotrophic lateral sclerosis
    D Rossi
    Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
    Cell Death Differ 15:1691-700. 2008
  2. doi request reprint Astrocytic dysfunction: insights on the role in neurodegeneration
    Daniela Rossi
    Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, 20133 Milan, Italy
    Brain Res Bull 80:224-32. 2009
  3. pmc The peroxisome proliferator-activated receptor γ (PPARγ) controls natural protective mechanisms against lipid peroxidation in amyotrophic lateral sclerosis
    Valeria Benedusi
    Center of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy
    J Biol Chem 287:35899-911. 2012
  4. ncbi request reprint Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease
    Daniela Rossi
    Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, Via Balzaretti, 9, 20133 Milan, Italy
    J Biol Chem 280:42088-96. 2005

Collaborators

Detail Information

Publications4

  1. doi request reprint Focal degeneration of astrocytes in amyotrophic lateral sclerosis
    D Rossi
    Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
    Cell Death Differ 15:1691-700. 2008
    ..We propose that excitotoxicity in ALS affects both motor neurons and astrocytes, favouring their local interactive degeneration. This new mechanistic hypothesis has implications for therapeutic interventions...
  2. doi request reprint Astrocytic dysfunction: insights on the role in neurodegeneration
    Daniela Rossi
    Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, 20133 Milan, Italy
    Brain Res Bull 80:224-32. 2009
    ....
  3. pmc The peroxisome proliferator-activated receptor γ (PPARγ) controls natural protective mechanisms against lipid peroxidation in amyotrophic lateral sclerosis
    Valeria Benedusi
    Center of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy
    J Biol Chem 287:35899-911. 2012
    ..Our findings indicate that anticipating natural protective reactions by pharmacologically modulating PPARγ transcriptional activity may attenuate neurodegeneration by limiting the damage induced by lipid peroxidation derivatives...
  4. ncbi request reprint Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease
    Daniela Rossi
    Department of Pharmacological Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan, Via Balzaretti, 9, 20133 Milan, Italy
    J Biol Chem 280:42088-96. 2005
    ..Reduced expression of DENN/MADD, a mediator of TNFalpha-PG coupling, might account for the defect. Alteration of this neuromodulatory astrocytic pathway is described here for the first time in relation to Alzheimer disease...