C R Rossi

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. doi request reprint Adherence to treatment guidelines for primary sarcomas affects patient survival: a side study of the European CONnective TIssue CAncer NETwork (CONTICANET)
    C R Rossi
    Melanoma and Sarcomas Unit, Veneto Institute of Oncology IRCCS, Padova, Italy
    Ann Oncol 24:1685-91. 2013
  2. pmc Clinicians' adherence versus non adherence to practice guidelines in the management of patients with sarcoma: a cost-effectiveness assessment in two European regions
    Lionel Perrier
    University of Lyon, F 69007 Lyon, France
    BMC Health Serv Res 12:82. 2012
  3. pmc Literature search on risk factors for sarcoma: PubMed and Google Scholar may be complementary sources
    Giuseppe Mastrangelo
    Department of Environmental Medicine and Public Health, Padua University, 35128 Padua, Italy
    BMC Res Notes 3:131. 2010
  4. pmc A European project on incidence, treatment, and outcome of sarcoma
    Giuseppe Mastrangelo
    Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy
    BMC Public Health 10:188. 2010
  5. pmc Sentinel node biopsy for breast cancer: is it already a standard of care? A survey of current practice in an Italian region
    Giorgio Zavagno
    University of Padova, Istituto di Clinica Chirurgica II, Padova 35128, Italy
    BMC Cancer 4:2. 2004
  6. ncbi request reprint Phase I-II study on isolation antiblastic fotemustine perfusion after dacarbazine chemosensitization for advanced melanoma of the extremities
    C R Rossi
    Clinica Chirurgica II, University of Padova, Padova, Italy
    Melanoma Res 13:293-7. 2003
  7. ncbi request reprint Hyperthermic isolated perfusion with low-dose tumor necrosis factor alpha and doxorubicin for the treatment of limb-threatening soft tissue sarcomas
    Carlo Riccardo Rossi
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Ann Surg Oncol 12:398-405. 2005
  8. ncbi request reprint Hyperthermic isolated perfusion with low-dose TNFalpha and doxorubicin in patients with locally advanced soft tissue limb sarcomas
    C R Rossi
    Clinica Chirurgica II, University of Padova, Italy
    J Chemother 16:58-61. 2004
  9. ncbi request reprint Gastrointestinal stromal tumors: from a surgical to a molecular approach
    Carlo Riccardo Rossi
    Department of Oncologic and Surgical Sciences, University of Padua, Padua, Italy
    Int J Cancer 107:171-6. 2003
  10. ncbi request reprint Hyperthermic intraperitoneal intraoperative chemotherapy for peritoneal carcinomatosis arising from gastric adenocarcinoma
    Carlo Riccardo Rossi
    Department of Oncological and Surgical Sciences, Clinica Chirurgica II, University of Padua, Italy
    Suppl Tumori 2:S54-7. 2003

Collaborators

Detail Information

Publications72

  1. doi request reprint Adherence to treatment guidelines for primary sarcomas affects patient survival: a side study of the European CONnective TIssue CAncer NETwork (CONTICANET)
    C R Rossi
    Melanoma and Sarcomas Unit, Veneto Institute of Oncology IRCCS, Padova, Italy
    Ann Oncol 24:1685-91. 2013
    ..e. surgery and radiotherapy) and chemotherapy on local disease control and survival in sarcoma patients was investigated in a European study conducted in an Italian region (Veneto)...
  2. pmc Clinicians' adherence versus non adherence to practice guidelines in the management of patients with sarcoma: a cost-effectiveness assessment in two European regions
    Lionel Perrier
    University of Lyon, F 69007 Lyon, France
    BMC Health Serv Res 12:82. 2012
    ....
  3. pmc Literature search on risk factors for sarcoma: PubMed and Google Scholar may be complementary sources
    Giuseppe Mastrangelo
    Department of Environmental Medicine and Public Health, Padua University, 35128 Padua, Italy
    BMC Res Notes 3:131. 2010
    ..The present study aims to appraise the relative proficiency of PubMed and Google Scholar...
  4. pmc A European project on incidence, treatment, and outcome of sarcoma
    Giuseppe Mastrangelo
    Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy
    BMC Public Health 10:188. 2010
    ....
  5. pmc Sentinel node biopsy for breast cancer: is it already a standard of care? A survey of current practice in an Italian region
    Giorgio Zavagno
    University of Padova, Istituto di Clinica Chirurgica II, Padova 35128, Italy
    BMC Cancer 4:2. 2004
    ..The aim of the present survey was therefore to investigate the way in which SNB is used by general surgeons working in the Veneto region, Italy...
  6. ncbi request reprint Phase I-II study on isolation antiblastic fotemustine perfusion after dacarbazine chemosensitization for advanced melanoma of the extremities
    C R Rossi
    Clinica Chirurgica II, University of Padova, Padova, Italy
    Melanoma Res 13:293-7. 2003
    ..The trial was then interrupted due to the low tolerability and poor efficacy of this perfusion regimen. At present, F ILP after DTIC chemosensitization should not be recommended for the treatment of locally advanced limb melanoma...
  7. ncbi request reprint Hyperthermic isolated perfusion with low-dose tumor necrosis factor alpha and doxorubicin for the treatment of limb-threatening soft tissue sarcomas
    Carlo Riccardo Rossi
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Ann Surg Oncol 12:398-405. 2005
    ..The aim of this study was to investigate the anticancer activity of a novel drug regimen including doxorubicin (DXR) and low-dose TNF-alpha...
  8. ncbi request reprint Hyperthermic isolated perfusion with low-dose TNFalpha and doxorubicin in patients with locally advanced soft tissue limb sarcomas
    C R Rossi
    Clinica Chirurgica II, University of Padova, Italy
    J Chemother 16:58-61. 2004
    ..Systemic side effects were negligible. The perfusate/plasma area under the curve (AUC) ratio for TNFalpha was 56. HILP with low-dose TNFalpha and DXR proved to be an active neoadjuvant drug regimen against limb-threatening STS...
  9. ncbi request reprint Gastrointestinal stromal tumors: from a surgical to a molecular approach
    Carlo Riccardo Rossi
    Department of Oncologic and Surgical Sciences, University of Padua, Padua, Italy
    Int J Cancer 107:171-6. 2003
    ..Molecular targeting of the critical pathogenetic mechanism underlying GIST might not only revolutionize the strategy to treat locally advanced and metastatic GIST but also improve disease control after macroscopically radical surgery...
  10. ncbi request reprint Hyperthermic intraperitoneal intraoperative chemotherapy for peritoneal carcinomatosis arising from gastric adenocarcinoma
    Carlo Riccardo Rossi
    Department of Oncological and Surgical Sciences, Clinica Chirurgica II, University of Padua, Italy
    Suppl Tumori 2:S54-7. 2003
    ..Patients with peritoneal carcinomatosis from gastric carcinoma have a dismal prognosis. Hyperthermic intraperitoneal intraoperative chemotherapy (HIIC) has been proposed to treat residual disease after cytoreductive surgery...
  11. ncbi request reprint Pharmacokinetics of intraperitoneal cisplatin and doxorubicin
    Carlo Riccardo Rossi
    Surgery Branch, Department of Oncological and Surgical Science, University of Padova, Via Giustiniani, 2 35128 Padova, Italy
    Surg Oncol Clin N Am 12:781-94. 2003
    ..Likewise, liposomes, which in animal models seem to favor tumor uptake of encapsulated DXR, should now be tested in the clinical setting...
  12. ncbi request reprint Melanoma - what is new in sentinel node biopsy and locoregional treatments in 2003? Report of a workshop at the Third Research Meeting on Melanoma, Milan, Italy, May 2003
    Carlo Riccardo Rossi
    Universita di Padova, Dipartimento di Scienze Oncologiche e Chirurgiche, Sezione di Clinica Chirurgica II, Via Giustiniani, 2, 35128 Padova, Italy
    Melanoma Res 14:329-32. 2004
    ..The main comments made by the respective rapporteurs are also summarized...
  13. ncbi request reprint Hyperthermic intraperitoneal intraoperative chemotherapy after cytoreductive surgery for the treatment of abdominal sarcomatosis: clinical outcome and prognostic factors in 60 consecutive patients
    Carlo Riccardo Rossi
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Padua, Italy
    Cancer 100:1943-50. 2004
    ..After a Phase I study on cytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy (HIIC), the authors reported the results of the treatment of 60 patients using this novel multimodal approach...
  14. ncbi request reprint The role of preoperative ultrasound scan in detecting lymph node metastasis before sentinel node biopsy in melanoma patients
    Carlo Riccardo Rossi
    Department of Oncological and Surgical Sciences, Istituto di Clinica Chirurgica Generale II, Padova, Italy
    J Surg Oncol 83:80-4. 2003
    ..To evaluate the efficacy of preoperative ultrasound (US) scanning in identifying lymph node metastasis before sentinel node biopsy (SNB), we conducted a prospective study on 125 patients with primary cutaneous melanoma (CM)...
  15. ncbi request reprint The impact of lymphoscintigraphy technique on the outcome of sentinel node biopsy in 1,313 patients with cutaneous melanoma: an Italian Multicentric Study (SOLISM-IMI)
    Carlo Riccardo Rossi
    Clinica Chirurgica 2, Universita di Padova, Padova, Italy
    J Nucl Med 47:234-41. 2006
    ..We report herein the results of this trial. The influence of some technical aspects on the outcome of SNB was also investigated, because a certain degree of variability was accepted in performing lymphoscintigraphy...
  16. ncbi request reprint Hyperthermic intraoperative intraperitoneal chemotherapy with cisplatin and doxorubicin in patients who undergo cytoreductive surgery for peritoneal carcinomatosis and sarcomatosis: phase I study
    Carlo R Rossi
    Dipartimento di Scienze Oncologiche e Chirurgiche, Sezione Clinica Chirurgica Generale II, Universita di Padova, Italy
    Cancer 94:492-9. 2002
    ..To evaluate whether this regimen could be used for other tumor types, the authors conducted a Phase I study on HIIC with doxorubicin and cisplatin in patients with peritoneal carcinomatosis or sarcomatosis...
  17. ncbi request reprint Hyperthermic isolated limb perfusion with low-dose tumor necrosis factor-alpha and melphalan for bulky in-transit melanoma metastases
    Carlo Riccardo Rossi
    Clinica Chirurgica Generale II, Dipartimento di Scienze Oncologiche e Chirurgiche, Universita di Padova, Padova, Italy
    Ann Surg Oncol 11:173-7. 2004
    ..We here report on the results of L-PAM and low-dose tumor necrosis factor (TNF)alpha HILP in patients with bulky disease...
  18. doi request reprint TNF-based isolated limb perfusion followed by consolidation biotherapy with systemic low-dose interferon alpha 2b in patients with in-transit melanoma metastases: a pilot trial
    Carlo Riccardo Rossi
    Department of Surgical and Oncological Sciences, Surgery Branch, University of Padua, Padua, Italy
    Ann Surg Oncol 15:1218-23. 2008
    ..However, most patients will ultimately experience disease recurrence. The aim of this pilot study was to test the hypothesis that systemic low-dose interferon alpha-2b (LDI) might consolidate the therapeutic effect of ILP...
  19. doi request reprint Factors predictive of nonsentinel lymph node involvement and clinical outcome in melanoma patients with metastatic sentinel lymph node
    Carlo Riccardo Rossi
    Department of Oncological and Surgical Sciences, Surgery Branch, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
    Ann Surg Oncol 15:1202-10. 2008
    ..This study tested the hypothesis that the microscopic features of metastatic SLNs might predict not only nonsentinel lymph node (NSLN) status, but also patients' clinical outcomes...
  20. ncbi request reprint TNF-based limb perfusion for cutaneous melanoma in transit metastases: suggestions for modification of the perfusional schedule
    C R Rossi
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Padova, Italy
    J Exp Clin Cancer Res 22:103-7. 2003
    ..Our results showed that it is possible to modify the perfusion schedule, without compromising the response rate but with lower cost and toxicity...
  21. ncbi request reprint Sentinel node biopsy and ultrasound scanning in cutaneous melanoma: clinical and technical considerations
    C R Rossi
    Dipartimento di Scienze Oncologiche e Chirurgiche, Sezione di Clinica Chirurgica II, Universita degli Studi di Padova, Via Giustiniani 2, 35128, Padova, Italy
    Eur J Cancer 36:895-900. 2000
    ..Breslow thickness and the number of metastatic SN(s), but not their type, are correlated with disease spread; CP10S contributed to the differentiation amongst the nodes and the determining of procedure's completion...
  22. doi request reprint Maximizing the clinical usefulness of a nomogram to select patients candidate to sentinel node biopsy for cutaneous melanoma
    S Pasquali
    Department of Oncological and Surgical Sciences, Surgery Branch, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Eur J Surg Oncol 37:675-80. 2011
    ..The negative predictive value (NPV) of this test, which might help identify low-risk patients who might be safely spared SN biopsy (SNB), has not been yet investigated...
  23. ncbi request reprint Hypoxic antiblastic stop-flow perfusion: clinical outcome and pharmacokinetic findings
    D Miotto
    Department of Oncological and Surgical Sciences, University of Padova, Italy
    J Chemother 16:44-7. 2004
    ..In conclusion, SFP is a feasible procedure. Toxicity and tumor response rates strictly depend upon drug leakage control...
  24. ncbi request reprint Multimodal treatment of peritoneal carcinomatosis and sarcomatosis
    P Pilati
    Clinica Chirurgica II, Dipartimento di Scienze Oncologiche e Chirurgiche, Padova, Italy
    Eur J Surg Oncol 27:125-34. 2001
    ....
  25. ncbi request reprint Cytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy for peritoneal carcinomatosis arising from colon adenocarcinoma
    Pierluigi Pilati
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Italy
    Ann Surg Oncol 10:508-13. 2003
    ..The purpose of this study was to evaluate the clinical outcome of this combined treatment...
  26. ncbi request reprint Histopathological characteristics of subsequent melanomas in patients with multiple primary melanomas
    A Vecchiato
    Melanoma and Sarcomas Unit, Veneto Institute of Oncology, Padova, ItalyDepartment of Oncological and Surgical Sciences, University of Padova, Padova, ItalyImmunology and Molecular Oncology Unit, Veneto Institute of Oncology, Padova, ItalyPathology Unit, Veneto Institute of Oncology, Padova, ItalyDermatology Unit, University of Padova, Padova
    J Eur Acad Dermatol Venereol 28:58-64. 2014
    ..Multiple primary melanomas (MPM) occur in up to 20% of melanoma patients, and subsequent tumours seem to have a favourable histopathological pattern...
  27. ncbi request reprint Hyperthermic isolated liver perfusion for unresectable liver cancers: pilot study
    M Lise
    Department of Oncological and Surgical Sciences, University of Padova, Italy
    J Chemother 16:37-9. 2004
    ..Locoregional toxicity was significant, which underscores the need for a more accurate preoperative evaluation of hepatic function...
  28. ncbi request reprint IL-10 stimulatory effects on human NK cells explored by gene profile analysis
    S Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Genes Immun 5:621-30. 2004
    ....
  29. ncbi request reprint Early detection of melanoma: an educational campaign in Padova, Italy
    C R Rossi
    Clinica Chirurgica II, Universita di Padova, Italy
    Melanoma Res 10:181-7. 2000
    ..0 mm versus 1.50 mm; P < 0.02)...
  30. ncbi request reprint Isolated limb perfusion in locally advanced cutaneous melanoma
    Carlo Riccardo Rossi
    Department of Surgical and Oncological Sciences Clinica Chirurgica II, University of Padova, Padova, Italy
    Semin Oncol 29:400-9. 2002
    ..As potential agents to be delivered through ILP, new vasoactive drugs and agents with new mechanisms of action that interplay with chemotherapy, as well as virus-mediated gene therapy, are being developed...
  31. ncbi request reprint N-ratio: a novel independent prognostic factor for patients with stage-III cutaneous melanoma
    Carlo Riccardo Rossi
    Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
    Ann Surg Oncol 15:310-5. 2008
    ..In this study, we tested the hypothesis that the ratio between metastatic and excised lymph nodes ("N-ratio") might have an independent prognostic value in patients with TNM stage-III cutaneous melanoma...
  32. ncbi request reprint A simplified procedure for continuous intraoperative external monitoring of systemic leakage during isolated limb perfusion
    D Casara
    Nuclear Medicine Service, Radiotherapy Department, University of Padua, Italy
    Tumori 88:S61-3. 2002
    ..Ten percent systemic leakage from the perfusion circuit is considered the maximum acceptable leakage. In this study we report our experience of a new leakage monitoring system...
  33. ncbi request reprint Subarachnoid anesthesia for loco-regional antiblastic perfusion with circulatory block (stop-flow perfusion)
    M Carron
    Department of Pharmacology and Anesthesiology, University of Padua, Padua, Italy
    Minerva Anestesiol 72:37-45. 2006
    ..The aim of this study was to evaluate if subarachnoid anesthesia could represent a safe and suitable anesthetic technique for this procedure...
  34. ncbi request reprint Stop-flow technique for loco-regional delivery of antiblastic agents: literature review and personal experience
    P Pilati
    Department of Oncological and Surgical Sciences, Clinica Chirurgica Generale II, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Eur J Surg Oncol 28:544-53. 2002
    ..Here, we discuss the principles underlying the SF technique as well as the worldwide experience published so far. We also report on the results of our pilot study on pelvic and limb SF perfusion...
  35. doi request reprint Electrochemotherapy for disseminated superficial metastases from malignant melanoma
    L G Campana
    Sarcoma and Melanoma Unit, Veneto Region Oncology Research Institute IOV IRCCS, Department of Oncological and Surgical Sciences, University of Padova, Padova, Italy
    Br J Surg 99:821-30. 2012
    ..The aim of the study was to determine predictive factors for effectiveness, toxicity and local disease control in patients with malignant melanoma treated with bleomycin-based electrochemotherapy (ECT)...
  36. ncbi request reprint The prognostic value of circulating tumor cells in patients with melanoma: a systematic review and meta-analysis
    Simone Mocellin
    Department of Oncological and Surgical Sciences, Surgery Branch, University of Padova, Padua, Italy
    Clin Cancer Res 12:4605-13. 2006
    ..We aimed to comprehensively and quantitatively summarize the evidence for the use of CTC to predict patients' clinical outcome...
  37. ncbi request reprint Support vector machine learning model for the prediction of sentinel node status in patients with cutaneous melanoma
    Simone Mocellin
    Clinica Chirurgica 2, Dipartimento di Scienze Oncologiche e Chirurgiche, Universita di Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Ann Surg Oncol 13:1113-22. 2006
    ..In this study, the predictive power of support vector machine (SVM)-based statistical analysis was tested...
  38. ncbi request reprint Increased TIA-1 gene expression in the tumor microenvironment after locoregional administration of tumor necrosis factor-alpha to patients with soft tissue limb sarcoma
    Simone Mocellin
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padua, Padua, Italy
    Int J Cancer 107:317-22. 2003
    ....
  39. ncbi request reprint Is there a relationship between influenza vaccinations and risk of melanoma? A population-based case-control study
    G Mastrangelo
    Istituto di Medicina del Lavoro, Universita di Padova, Italy
    Eur J Epidemiol 16:777-82. 2000
    ....
  40. ncbi request reprint High-sensitivity power Doppler imaging of normal superficial lymph nodes
    Roberto Stramare
    Department of Medical and Diagnostic Sciences and Special Therapies, Radiology, University of Padua, Via Giustiani 2, Padua, Italy
    J Clin Ultrasound 32:273-6. 2004
    ..This study was conducted to describe the various patterns of vascularity of the normal superficial lymph nodes detected using high-sensitivity power Doppler imaging according to the dimension and anatomic location of the nodes...
  41. ncbi request reprint Optimized procedure of real-time systemic leakage monitoring during isolated limb perfusion using a hand held gamma probe and 99mTc-HSA
    D Casara
    2nd Nuclear Medicine Service, General Hospital and University of Padova, Italy
    Nucl Med Commun 25:61-6. 2004
    ..Moreover, using 99mTc-HSA as the radiotracer, the risk of radioactive contamination is significantly lower in comparison with 131I-HSA...
  42. ncbi request reprint Subareolar injection for sentinel lymph node location in breast cancer
    Giorgio Zavagno
    Clinica Chirurgica II, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
    Eur J Surg Oncol 28:701-4. 2002
    ..In order to test this hypothesis, we ascertained whether subareolar blue dye injection and subdermal radioisotope injection close to the tumour identify the same axillary nodes...
  43. ncbi request reprint Glutathione transferases as targets for cancer therapy
    Paolo Ruzza
    Institute of Biomolecular Chemistry of CNR, Padova, Italy
    Anticancer Agents Med Chem 9:763-77. 2009
    ..In the present review we discuss the current structural and pharmacological knowledge of both types of GST-targeting compounds...
  44. ncbi request reprint Large and dissimilar repertoire of Melan-A/MART-1-specific CTL in metastatic lesions and blood of a melanoma patient
    Susanna Mandruzzato
    Department of Oncology, University of Padova, Padova, Italy
    J Immunol 169:4017-24. 2002
    ..Taken together, these results buttress the notion that the CTLs recognizing the immunodominant Ag of Melan-A comprise a high number of different clonotypic TCR, of which only some exhibit common features in the CDR3...
  45. ncbi request reprint Tumour-localizing and -photosensitising properties of meso-tetra(4-nido-carboranylphenyl)porphyrin (H2TCP)
    Clara Fabris
    Department of Biology, University of Padova, Via Ugo Bassi, 58 B, 35121 Padova, Italy
    J Photochem Photobiol B 89:131-8. 2007
    ..Thus, this porphyrin could act as both a photodynamic therapy agent and a radiosensitising agent for boron neutron capture therapy...
  46. ncbi request reprint Hypoxic antiblastic stop-flow limb perfusion: clinical outcome and pharmacokinetic findings of a novel treatment for in transit melanoma metastases
    Pierluigi Pilati
    Department of Oncological and Surgical Sciences, University of Padova, Padova, Italy
    Oncol Rep 12:895-901. 2004
    ..Toxicity and tumor response rates strictly depend upon drug leakage control. Further efforts should be made to exploit the potential anti-tumor activity of this novel locoregional drug delivery system...
  47. ncbi request reprint Evaluation of lymph node perfusion using continuous mode harmonic ultrasonography with a second-generation contrast agent
    Leopoldo Rubaltelli
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Padua, Italy
    J Ultrasound Med 23:829-36. 2004
    ....
  48. ncbi request reprint Eruptive melanocytic nevi in patients with renal allografts: report of 10 cases with dermoscopic findings
    Mauro Alaibac
    Institute of Dermatology, University of Padua, Via C Battisti 206, Padua, 35121 Italy
    J Am Acad Dermatol 49:1020-2. 2003
    ....
  49. ncbi request reprint Induction of endothelial nitric oxide synthase expression by melanoma sensitizes endothelial cells to tumor necrosis factor-driven cytotoxicity
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, Padova, Italy
    Clin Cancer Res 10:6879-86. 2004
    ..We investigated the role of endothelial nitric oxide synthase in determining the tumor-selective activity of TNF...
  50. ncbi request reprint TNFalpha-based isolated perfusion for limb-threatening soft tissue sarcomas: state of the art and future trends
    Carlo Riccardo Rossi
    Department of Oncological and Surgical Sciences, University of Padova, Italy carlor rossi2unipd it
    J Immunother 26:291-300. 2003
    ..The potential future developments of this locoregional therapeutic approach will also be reported...
  51. ncbi request reprint Automated quantitative evaluation of lymph node perfusion on contrast-enhanced sonography
    Leopoldo Rubaltelli
    Department of Medical Diagnostic Sciences and Special Therapies, University of Padua Italy, Via Giustiniani 2, Padua 35100, Italy
    AJR Am J Roentgenol 188:977-83. 2007
    ....
  52. ncbi request reprint Use of laser scanning cytometry to study tumor microenvironment
    S Mocellin
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Italy
    Histol Histopathol 18:609-15. 2003
    ....
  53. ncbi request reprint Correlation between melphalan pharmacokinetics and hepatic toxicity following hyperthermic isolated liver perfusion for unresectable metastatic disease
    Simone Mocellin
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
    Ann Surg Oncol 14:802-9. 2007
    ....
  54. ncbi request reprint Tumor necrosis factor, cancer and anticancer therapy
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, Policlinico Universitario, 6 piano, Via Giustiniani, 2, 35128 Padova, Italy
    Cytokine Growth Factor Rev 16:35-53. 2005
    ..Recent insights that might pave the way to further exploitation of the antineoplastic potential of TNF are also discussed...
  55. ncbi request reprint Strategies to enhance the anticancer potential of TNF
    Pierluigi Pilati
    Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Front Biosci 13:3181-93. 2008
    ..This would enhance the anticancer activity of current TNF-based locoregional regimens and would pave the way to the systemic administration of this cytokine and thus to a much wider clinical experimentation of TNF in the oncology field...
  56. ncbi request reprint Dissecting tumor responsiveness to immunotherapy: the experience of peptide-based melanoma vaccines
    Simone Mocellin
    Clinica Chirurgica Generale II, Dipartimento di Scienze Oncologiche e Chirurgiche, Universita di Padova, Via Giustiniani 2, 35128 Padua, Italy
    Biochim Biophys Acta 1653:61-71. 2003
    ..The hypothesized role of innate immunity in predetermining tumor responsiveness to immunotherapeutic manipulation is also discussed...
  57. doi request reprint The number of excised lymph nodes is associated with survival of melanoma patients with lymph node metastasis
    C R Rossi
    Melanoma and Sarcomas Unit, Veneto Institute of Oncology, Padova, Italy
    Ann Oncol 25:240-6. 2014
    ..This study aims to evaluate the association between the number of excised regional lymph nodes (LNs) and melanoma-specific survival...
  58. ncbi request reprint Molecular oncology in the post-genomic era: the challenge of proteomics
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Trends Mol Med 10:24-32. 2004
  59. ncbi request reprint Cancer vaccine development: on the way to break immune tolerance to malignant cells
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, Italy
    Exp Cell Res 299:267-78. 2004
    ....
  60. pmc DNA array-based gene profiling: from surgical specimen to the molecular portrait of cancer
    Simone Mocellin
    Surgery Branch, Department of Oncological and Surgical Sciences, University of Padova, Italy
    Ann Surg 241:16-26. 2005
    ..In the present work, we discuss the technical features characterizing this powerful laboratory tool and review the applications so far described in the field of oncology...
  61. ncbi request reprint Colorectal cancer vaccines: principles, results, and perspectives
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, 35128 Padova, Italy
    Gastroenterology 127:1821-37. 2004
    ..We also discuss the most recent preclinical tumor immunology insights that might change the way to design the next generation of cancer vaccines, hopefully improving the effectiveness of such a biotherapeutic approach...
  62. ncbi request reprint Principles of gene microarray data analysis
    Simone Mocellin
    Clinica Chirurgica II, Dipartimento di Scienze Oncologiche e Chirurgiche, University of Padova, Via Giustiniani 2, Italy
    Adv Exp Med Biol 593:19-30. 2007
    ..Therefore, it is of paramount importance for both researchers and clinicians to know the principles underlying the analysis of the huge amount of data generated with microarray technology...
  63. doi request reprint Sentinel node biopsy in pediatric soft tissue sarcomas of extremities
    Federica De Corti
    Department of Pediatrics, Division of Pediatric Surgery, University Hospital of Padua, Padua, Italy
    Pediatr Blood Cancer 52:51-4. 2009
    ..However, only few reports describe this procedure for the evaluation of regional lymph nodes in childhood and adolescents. Our experience with sentinel node biopsy in soft tissue sarcomas of extremities in children is reported...
  64. ncbi request reprint Circulating tumor cells: the 'leukemic phase' of solid cancers
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Trends Mol Med 12:130-9. 2006
    ..This would provide a formidable tool for prognosis evaluation, anticancer-drug development and, ultimately, cancer-therapy personalization...
  65. ncbi request reprint The multifaceted relationship between IL-10 and adaptive immunity: putting together the pieces of a puzzle
    Simone Mocellin
    Department of Oncological and Surgical Sciences, University of Padova, Clinica Chirurgica II, Via Giustiniani, 2, 35128 Padova, Italy
    Cytokine Growth Factor Rev 15:61-76. 2004
    ..g. infectious diseases, autoimmunity, allergy, cancer and transplantation) involving adaptive immunity...
  66. ncbi request reprint Deliberate hypoxic pelvic and limb chemoperfusion in the treatment of recurrent melanoma
    Stefano Guadagni
    Department of Surgical Sciences, University of L Aquila, 67010 L Aquila, Italy
    Am J Surg 183:28-36. 2002
    ..A simplified hypoxic pelvic and limb perfusion has been recently recommended to provide therapeutic options for palliation and possibly cure...
  67. ncbi request reprint Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma: a pilot study
    Stefano Guadagni
    Department of Surgical Sciences, University of L Aquila, L Aquila, Italy
    Melanoma Res 13:51-8. 2003
    ..Further studies are necessary to establish whether the response rates can be improved by using different drug regimens...
  68. ncbi request reprint Hyperthermic isolation limb perfusion with TNFalpha in the treatment of in-transit melanoma metastasis
    Franco Di Filippo
    Regina Elena National Cancer Institute, Rome, Italy
    In Vivo 20:739-42. 2006
    ..After eighteen years from its first clinical application, more than 300 patients have been treated. The aim of this study is to clarify two major arguments: the TNFalpha dose and eligibility criteria for patient selection...
  69. ncbi request reprint The consensus statement on the locoregional treatment of abdominal sarcomatosis
    Carlo Riccardo Rossi
    Sarcoma and Melanoma Unit, Clinica Chirurgica II, University of Padova Italy
    J Surg Oncol 98:291-4. 2008
    ..A questionnaire was placed on the website of the 5th International Workshop on Peritoneal Surface Malignancy and the experts voted via internet...
  70. doi request reprint The melanoma molecular map project
    Simone Mocellin
    Melanoma Res 18:163-5. 2008
  71. ncbi request reprint Usefulness and limits of ultrasound-guided hook-wire positioning for localisation of soft tissue lesions prior to surgery
    Alberto Tregnaghi
    Sezione di Radiologia, Dipartimento di Scienze Medico Diagnostiche e Terapie Speciali, Universita degli Studi di Padova, Padova
    Radiol Med 110:646-54. 2005
    ..The aim of our study was to assess the usefulness of positioning metal wires under ultrasound guidance for localising soft tissue lesions in the preoperative phase...
  72. ncbi request reprint Tumor microenvironment: what have we learned studying the immune response in this puzzling battlefield?
    Simone Mocellin
    Immunnogenetics Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Tumori 88:437-44. 2002
    ..As a model, we will discuss the observed immune response to tumor antigen -specific immunization and its relationship with the systemic administration of IL-2...