Antonella Rosa

Summary

Affiliation: University of Cagliari
Country: Italy

Publications

  1. doi request reprint Protective effect of vanilloids against tert-butyl hydroperoxide-induced oxidative stress in vero cells culture
    Antonella Rosa
    Dip Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    J Agric Food Chem 56:3546-53. 2008
  2. doi request reprint Mugil cephalus roe oil obtained by supercritical fluid extraction affects the lipid profile and viability in cancer HeLa and B16F10 cells
    A Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4 5 SS 554, 09042 Monserrato, CA, Italy
    Food Funct 7:4092-103. 2016
  3. doi request reprint Antioxidant profile of strawberry tree honey and its marker homogentisic acid in several models of oxidative stress
    Antonella Rosa
    Dipartimento di Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy Electronic address
    Food Chem 129:1045-53. 2011
  4. doi request reprint A diet enriched with Mugil cephalus processed roes modulates the tissue lipid profile in healthy rats: a biochemical and chemometric assessment
    A Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4 5 SS 554, 09042 Monserrato, CA, Italy
    Food Funct 7:202-11. 2016
  5. doi request reprint Monoolein-based cubosomes affect lipid profile in HeLa cells
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy Electronic address
    Chem Phys Lipids 191:96-105. 2015
  6. pmc Maltese mushroom (Cynomorium coccineum L.) as source of oil with potential anticancer activity
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4 5, Monserrato, 09042 Cagliari, Italy
    Nutrients 7:849-64. 2015
  7. doi request reprint Lipid profiles in brains from sheep with natural scrapie
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy Electronic address
    Chem Phys Lipids 175:33-40. 2013
  8. doi request reprint Potential anti-tumor effects of Mugil cephalus processed roe extracts on colon cancer cells
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy Electronic address
    Food Chem Toxicol 60:471-8. 2013
  9. doi request reprint Chemical composition and effect on intestinal Caco-2 cell viability and lipid profile of fixed oil from Cynomorium coccineum L
    Antonella Rosa
    Dip Scienze Biomediche, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    Food Chem Toxicol 50:3799-807. 2012
  10. doi request reprint Protective role of arzanol against lipid peroxidation in biological systems
    Antonella Rosa
    Dip Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    Chem Phys Lipids 164:24-32. 2011

Detail Information

Publications35

  1. doi request reprint Protective effect of vanilloids against tert-butyl hydroperoxide-induced oxidative stress in vero cells culture
    Antonella Rosa
    Dip Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    J Agric Food Chem 56:3546-53. 2008
    ..Both compounds were effective against peroxidation of cell membrane lipids induced by TBH, with synthetic capsiate essentially acting as a pro-drug of vanillyl alcohol, its hydrophilic hydrolytic derivative...
  2. doi request reprint Mugil cephalus roe oil obtained by supercritical fluid extraction affects the lipid profile and viability in cancer HeLa and B16F10 cells
    A Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4 5 SS 554, 09042 Monserrato, CA, Italy
    Food Funct 7:4092-103. 2016
    ..Bottarga oil treatment influenced the synthesis of intracellular membranes and accumulation of cytoplasmic lipid droplets in cancer cells. ..
  3. doi request reprint Antioxidant profile of strawberry tree honey and its marker homogentisic acid in several models of oxidative stress
    Antonella Rosa
    Dipartimento di Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy Electronic address
    Food Chem 129:1045-53. 2011
    ..The results of the work qualify HGA as natural antioxidant, able to exert a significant in vitro protective effect and to contribute to the strawberry tree honey antioxidant activity. ..
  4. doi request reprint A diet enriched with Mugil cephalus processed roes modulates the tissue lipid profile in healthy rats: a biochemical and chemometric assessment
    A Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4 5 SS 554, 09042 Monserrato, CA, Italy
    Food Funct 7:202-11. 2016
    ....
  5. doi request reprint Monoolein-based cubosomes affect lipid profile in HeLa cells
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy Electronic address
    Chem Phys Lipids 191:96-105. 2015
    ....
  6. pmc Maltese mushroom (Cynomorium coccineum L.) as source of oil with potential anticancer activity
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4 5, Monserrato, 09042 Cagliari, Italy
    Nutrients 7:849-64. 2015
    ..The results qualify C. coccineum as a resource of oil, with potential benefits in cancer prevention, for nutraceutical and pharmaceutical applications. ..
  7. doi request reprint Lipid profiles in brains from sheep with natural scrapie
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy Electronic address
    Chem Phys Lipids 175:33-40. 2013
    ..Such physicochemical alteration would have a profound impact on the raft thermodynamic properties, its spatial organization, and signal transduction, all potentially relevant for prion generation. ..
  8. doi request reprint Potential anti-tumor effects of Mugil cephalus processed roe extracts on colon cancer cells
    Antonella Rosa
    Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy Electronic address
    Food Chem Toxicol 60:471-8. 2013
    ..The results showed interesting anti-tumor properties of bottarga lipids, and qualify this fish product as a food with nutraceutical properties and potential benefits in colon cancer prevention...
  9. doi request reprint Chemical composition and effect on intestinal Caco-2 cell viability and lipid profile of fixed oil from Cynomorium coccineum L
    Antonella Rosa
    Dip Scienze Biomediche, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    Food Chem Toxicol 50:3799-807. 2012
    ..The results showed remarkable biological activity of Maltese mushroom oil, and qualify it as a potential resource for food/pharmaceutical applications...
  10. doi request reprint Protective role of arzanol against lipid peroxidation in biological systems
    Antonella Rosa
    Dip Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    Chem Phys Lipids 164:24-32. 2011
    ..36×10(-5) and 2.20±0.004×10(-5)cm/s, respectively, suggesting a passive diffusion pathway. The results of the work qualify arzanol as a potent natural antioxidant with a protective effect against lipid oxidation in biological systems...
  11. doi request reprint Effect of storage conditions on lipid components and color of Mugil cephalus processed roes
    Antonella Rosa
    Dipartamento di Biologia Sperimentale, Universita degli Studi di Cagliari, Cagliari, Italy
    J Food Sci 77:C107-14. 2012
    ..The resistance against the oxidation of the isolated bottarga lipids was also assessed in dry state at several temperatures (37, 75, and 140 °C)...
  12. doi request reprint Effect of aqueous and lipophilic mullet (Mugil cephalus) Bottarga extracts on the growth and lipid profile of intestinal Caco-2 cells
    Antonella Rosa
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Università degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    J Agric Food Chem 59:1658-66. 2011
    ..Moreover, the bottarga lipid extract showed an in vitro inhibitory effect on the growth of a colon cancer cell line (undifferentiated Caco-2 cells)...
  13. doi request reprint Protective effect and relation structure-activity of nonivamide and iododerivatives in several models of lipid oxidation
    Antonella Rosa
    Dipartimento di Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cagliari, Italy
    Chem Biol Interact 180:183-92. 2009
    ..This, coupled to its lacks of pungency and TRPV1 inhibiting properties, qualifies this phenolic compound as an attractive candidate for further investigations in vivo...
  14. doi request reprint Protective effect of the oligomeric acylphloroglucinols from Myrtus communis on cholesterol and human low density lipoprotein oxidation
    Antonella Rosa
    Dipartimento Biologia Sperimentale, Sezione Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato CA, Italy
    Chem Phys Lipids 155:16-23. 2008
    ....
  15. ncbi request reprint Antioxidant activity of capsinoids
    Antonella Rosa
    Dipartimento Biologia Sperimentale, Sezione Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    J Agric Food Chem 50:7396-401. 2002
    ..Vanillyl nonanoate, a simple capsinoid mimic, was also tested on cell cultures for cytotoxic activity and the capacity to inhibit FeCl(3)-induced oxidation...
  16. ncbi request reprint Cholesterol as target of Fe-NTA-induced lipid peroxidation in rat tissues
    Antonella Rosa
    Dip Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, Km 4 5 SS 554, 09042 Monserrato, Cagliari, Italy
    Toxicol Lett 157:1-8. 2005
    ..This is the first report on cholesterol reduction and accumulated 7-ketocholesterol in the tissues of rats treated with Fe-NTA as a consequence of lipid peroxidation...
  17. ncbi request reprint Protective effect of capsinoid on lipid peroxidation in rat tissues induced by Fe-NTA
    Antonella Rosa
    Dip Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, Monserrato, Italy
    Free Radic Res 39:1155-62. 2005
    ..The protective effect of SCPT and two analogues (vanillyl alcohol and vanillin) during the linoleic acid and cholesterol oxidation was investigated in in vitro systems, providing evidence of definite structure-activity relationships...
  18. ncbi request reprint Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum
    Antonella Rosa
    Dipartimento di Biologia Sperimentale, Sez Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    Chem Biol Interact 165:117-26. 2007
    ..The results of the present work suggest that the natural compound arzanol exerts useful antioxidant properties in different in vitro systems of lipid peroxidation...
  19. doi request reprint Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Food Chem Toxicol 48:3008-16. 2010
    ..In vitro trials, where the simple phenols were tested during linoleic acid and cholesterol oxidation, gave evidence of a direct scavenging of peroxyl radicals and suggested a hydrogen atom-donating activity...
  20. doi request reprint Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H(2)O(2) induced oxidative damage
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, Monserrato, Italy
    Chem Biol Interact 193:232-9. 2011
    ....
  21. doi request reprint Protective effect of hydroxytyrosol and its metabolite homovanillic alcohol on H(2)O(2) induced lipid peroxidation in renal tubular epithelial cells
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Food Chem Toxicol 46:2984-90. 2008
    ..HVA exerted a comparable activity, thus both HT and HVA were able to prevent in renal cells the lipid peroxidation process that plays a central role in tubular cell injury...
  22. ncbi request reprint L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Clin Nutr 23:183-93. 2004
    ..The aim of this study was to assess the effect of oral administration of L-ergothioneine on the oxidative damage in vivo caused by the Fenton reagent ferric-nitrilotriacetate...
  23. ncbi request reprint Protective effect of olive oil minor polar components against oxidative damage in rats treated with ferric-nitrilotriacetate
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Food Chem Toxicol 45:2434-40. 2007
    ..In summary, MPC administration protects organs against lipid peroxidation and conserves the endogenous alpha-tocopherol...
  24. doi request reprint Extraction and separation of volatile and fixed oils from seeds of Myristica fragrans by supercritical CO₂: chemical composition and cytotoxic activity on Caco-2 cancer cells
    Alessandra Piras
    Dipartamento di Scienze Chimiche, Univesità degli Studi di Cagliari, Cagliari, Italy
    J Food Sci 77:C448-53. 2012
    ..Moreover, the essential oil obtained from nutmeg, as well as myristicin, showed a significant in vitro inhibitory effect on the growth of a colon cancer cell line (undifferentiated Caco-2 cells)...
  25. ncbi request reprint Antioxidant activity of oligomeric acylphloroglucinols from Myrtus communis L
    Antonella Rosa
    Dipartimento Biologia Sperimentale, Sezione Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, SS 554, Km 4 5, 09042 Monserrato, Cagliari, Italy
    Free Radic Res 37:1013-9. 2003
    ..The results of these studies established semimyrtucommulone as a novel dietary antioxidant lead...
  26. ncbi request reprint Lipid peroxidation in plasma of rats treated with ferric-nitrilotriacetate, in relation to kidney and liver modifications
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Biofactors 23:35-44. 2005
    ....
  27. doi request reprint Wine extracts from Sardinian grape varieties attenuate membrane oxidative damage in Caco-2 cell monolayers
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Food Chem 134:2105-13. 2012
    ..Our findings point out a direct antioxidant action of the wine extracts on enterocytes exposed to oxidising species and further support the opinion that total phenolic content is not essential for antioxidant activity...
  28. pmc Evaluation of antioxidant potential of “maltese mushroom” (Cynomorium coccineum) by means of multiple chemical and biological assays
    Paolo Zucca
    Department of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy
    Nutrients 5:149-61. 2013
    ..Therefore, Maltese mushroom can be considered a valuable source of antioxidants and phytochemicals useful in the preparation of nutraceuticals and functional foods...
  29. ncbi request reprint Antioxidant activity of supercritical extract of Melissa officinalis subsp. officinalis and Melissa officinalis subsp. inodora
    Bruno Marongiu
    Dipartimento di Scienze Chimiche, Universita di Cagliari, Cittadella Universitaria di Monserrato, 09042 Cagliari, Italy
    Phytother Res 18:789-92. 2004
    ..officinalis and M. inodora extracts showed an antioxidant activity, and no significant differences in their efficacy were observed. None showed any prooxidant activity...
  30. doi request reprint Extraction of oil from wheat germ by supercritical CO2
    Alessandra Piras
    Dipartimento di Scienze Chimiche, Universita degli Studi di Cagliari, Cittadella Universitaria di Monserrato, SS 554, km 4 500 09042 Cagliari, Italy
    Molecules 14:2573-81. 2009
    ....
  31. doi request reprint (1)H NMR brain metabonomics of scrapie exposed sheep
    Paola Scano
    Department of Chemical and Geological Sciences, University of Cagliari, Monserrato, Italy
    Mol Biosyst 11:2008-16. 2015
    ....
  32. doi request reprint Modifications of the 1H NMR metabolite profile of processed mullet (Mugil cephalus) roes under different storage conditions
    Paola Scano
    Dipartimento di Scienze Chimiche, Universita degli Studi di Cagliari, Cittadella Universitaria di Monserrato, SS 554 Bivio per Sestu, 09042 Cagliari, Italy
    Magn Reson Chem 50:436-42. 2012
    ..These changes were observed at different storage conditions, with more pronounced trends in the samples stored at room temperature. The role of metabolites in food aging is discussed...
  33. ncbi request reprint Novel approach to study oxidative stability of extra virgin olive oils: importance of alpha-tocopherol concentration
    Monica Deiana
    Dip di Biologia Sperimentale, Sez di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria, KM 4 5 SS554, 09042 Monserrato CA, Italy
    J Agric Food Chem 50:4342-6. 2002
    ..The initial amount of alpha-tocopherol is one of the components that influences oil oxidative susceptibility...
  34. doi request reprint Antioxidant activity, cytotoxic activity and metabolic profiling of juices obtained from saffron (Crocus sativus L.) floral by-products
    Carlo I G Tuberoso
    Department of Life and Environmental Sciences, University of Cagliari, Via Ospedale, 72, 09124 Cagliari, Italy Electronic address
    Food Chem 199:18-27. 2016
    ..This study suggests that juices from saffron floral by-products could potentially be used to develop new products for the food and health industry...
  35. ncbi request reprint Assessment of the ability of the antioxidant cocktail-derived from fermentation of plants with effective microorganisms (EM-X) to modulate oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of poly- and mono-unsaturated fat
    Okezie I Aruoma
    Division of Neuroscience and Psychological Medicine, Department of Neuroinflammation, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK
    Toxicol Lett 135:209-17. 2002
    ....