Research Topics
| V RochiraSummaryAffiliation: University of Modena and Reggio Emilia Country: Italy Publications
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Detail Information
Publications
Congenital estrogen deficiency: in search of the estrogen role in human male reproductionV Rochira
Department of Internal Medicine, University of Modena and Reggio Emilia, Via del Pozzo 71, Policlinico, 41100, Modena, Italy
Mol Cell Endocrinol 178:107-15. 2001....
Role of estrogen on bone in the human male: insights from the natural models of congenital estrogen deficiencyV Rochira
Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41100, Modena, Italy
Mol Cell Endocrinol 178:215-20. 2001..In addition progress have been made in the treatment of such a rare disease even though further studies are needed to a definitive understanding of this issue...
Pituitary function in a man with congenital aromatase deficiency: effect of different doses of transdermal E2 on basal and stimulated pituitary hormonesVincenzo Rochira
Center for Endocrinology, Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
J Clin Endocrinol Metab 87:2857-62. 2002..Finally, the congenital lack of estrogen activity seems to be associated with a slightly impaired secretion of PRL and TSH, suggesting a possible role of estrogens on the pituitary secretion of these hormones in the human male...
Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in menVincenzo Rochira
Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41100 Modena, Italy
Mol Cell Endocrinol 193:19-28. 2002..Finally, the putative use of estrogen in men and the use of aromatase inhibitors and antiestrogen for male disorders are discussed...
Sex steroids and sexual desire mechanismV Rochira
Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Modena, Italy
J Endocrinol Invest 26:29-36. 2003....
Bone loss, sex steroids and male age related hypogonadismV Rochira
Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Policlinico, 41100 Modena, Italy
J Endocrinol Invest 28:46-8. 2005..Recently, the study of sex steroids on bone physiology in men has highlighted the central role of estrogens on bone pathophysiology. This review focuses on the relative role of sex steroids on bone loss in aging men...
The effects of long-term raloxifene and estradiol treatments on bone in a patient with congenital aromatase deficiencyL Zirilli
Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Via Giardini 1355, 41100 Modena, Italy
Bone 45:827-32. 2009....
Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho)physiologyV Rochira
Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
Eur J Endocrinol 154:175-85. 2006..In particular, the role of sex steroids on bone sexual dimorphism in health and disease has been analyzed...
Oestradiol replacement treatment and glucose homeostasis in two men with congenital aromatase deficiency: evidence for a role of oestradiol and sex steroids imbalance on insulin sensitivity in menV Rochira
Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Italy
Diabet Med 24:1491-5. 2007..To investigate the effects of sex steroids and oestrogen on insulin sensitivity in men, we studied two male adults with aromatase deficiency (subject 1 and subject 2)...
Bilateral osteonecrosis of the femoral head in an adult man affected by congenital estrogen deficiencyA Balestrieri
Department of Internal Medicine, Chair of Endocrinology, University of Modena and Reggio Emilia, Policlinico, Modena, Italy
J Endocrinol Invest 26:762-4. 2003..The possibility of development of bone necrosis in patients affected by congenital estrogen deficiency needs to be considered and magnetic resonance imaging can be a useful method for an early detection of this disease...
Hypopituitarism and HIV-infection: a new comorbidity in the HAART era?L Zirilli
Chair of Endocrinology, Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, 41100 Modena, Italy
J Endocrinol Invest 31:33-8. 2008....
Differentiated thyroid carcinoma (DTC) in a young woman with Peutz-Jeghers syndrome: are these two conditions associated?L Zirilli
Integrated Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Ospedale S Agostino Estense di Baggiovara, Via Giardini 1355, Baggiovara, Modena, Italy
Exp Clin Endocrinol Diabetes 117:234-9. 2009..Differentiated thyroid cancers (DTCs) present mainly as sporadic, but they may have also a familial component. We present a case of PJS in a caucasian 25 years-old woman, who developed a DTC...
A novel mutation in the human aromatase gene: insights on the relationship among serum estradiol, longitudinal growth and bone mineral density in an adult man under estrogen replacement treatmentFabio Lanfranco
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Italy
Bone 43:628-35. 2008....
The osteoporotic male: overlooked and undermanaged?Bruno Madeo
Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Ospedale S Agostino Estense di Baggiovara, Modena, Italy
Clin Interv Aging 2:305-12. 2007..This review focuses on the clinical approach and treatment strategy for osteoporosis in men with particular attention to its relationship with male hypogonadism...
A novel compound heterozygous mutation of the aromatase gene in an adult man: reinforced evidence on the relationship between congenital oestrogen deficiency, adiposity and the metabolic syndromeLaura Maffei
Consultorios Asociados de Endocrinologia Buenos Aires, Argentina
Clin Endocrinol (Oxf) 67:218-24. 2007..Descriptions of new cases of human aromatase deficiency are useful for a better understanding of male oestrogen pathophysiology, as some aspects remain controversial...
Skeletal effects of long-term estrogen and testosterone replacement treatment in a man with congenital aromatase deficiency: evidences of a priming effect of estrogen for sex steroids action on boneVincenzo Rochira
Department of Medicine, University of Modena and Reggio Emilia, Ospedale S Agostino Estense di Baggiovara, Via Giardini 1355, Baggiovara, 41100 Modena, Italy
Bone 40:1662-8. 2007..Only the combined treatment led to optimal parameters of aBMD suggesting that testosterone needs estrogens as a permissive factor for a direct androgen anabolic action on bone in men...
Hypothalamic-pituitary-gonadal axis in two men with aromatase deficiency: evidence that circulating estrogens are required at the hypothalamic level for the integrity of gonadotropin negative feedbackVincenzo Rochira
Integrated Department of Medicine, Endocrinology, Metabolism and Geriatrics, University of Modena and Reggio Emilia, Modena, Italy
Eur J Endocrinol 155:513-22. 2006....
Sex steroids and sexual desire in a man with a novel mutation of aromatase gene and hypogonadismCesare Carani
Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
Psychoneuroendocrinology 30:413-7. 2005..Sexual behavior is mainly under the control of cognitive functions in men, but sex steroids may modulate some aspects of male sexuality. Our findings suggest that in men estrogens could play a role in sexual activity...
Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatmentLaura Maffei
Consultorios Asociados de Endocrinologia, 1425 Buenos Aires, Argentina
J Clin Endocrinol Metab 89:61-70. 2004..This new case of aromatase deficiency confirms previous data on bone maturation and mineralization, and it reveals a high risk for the precocious development of cardiovascular disease in young aromatase-deficient men...
Human models of aromatase deficiencyLucia Zirilli
Integrated Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Via Giardini 1355, 41100 Modena, Italy
J Steroid Biochem Mol Biol 109:212-8. 2008..Moreover, the increasing knowledge on the role of estrogen in several metabolic pathways could be important for a better management of several metabolic diseases...
Sildenafil improves sleep-related erections in hypogonadal men: evidence from a randomized, placebo-controlled, crossover study of a synergic role for both testosterone and sildenafil on penile erectionsVincenzo Rochira
Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy
J Androl 27:165-75. 2006..Furthermore, these data strongly support the idea of a synergic effect on sleep-related erections of sildenafil and testosterone...
Estrogens in males: what have we learned in the last 10 years?Vincenzo Rochira
Integrated Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Modena 41100, Italy
Asian J Androl 7:3-20. 2005..The continuing increase in data obtained, and recent discoveries in this area will enable a better understanding of male physiology; these, in turn, will have important clinical implications...
