V Rochira

Summary

Affiliation: University of Modena and Reggio Emilia
Country: Italy

Publications

  1. ncbi request reprint Congenital estrogen deficiency: in search of the estrogen role in human male reproduction
    V Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Via del Pozzo 71, Policlinico, 41100, Modena, Italy
    Mol Cell Endocrinol 178:107-15. 2001
  2. ncbi request reprint Role of estrogen on bone in the human male: insights from the natural models of congenital estrogen deficiency
    V Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41100, Modena, Italy
    Mol Cell Endocrinol 178:215-20. 2001
  3. ncbi request reprint Pituitary function in a man with congenital aromatase deficiency: effect of different doses of transdermal E2 on basal and stimulated pituitary hormones
    Vincenzo Rochira
    Center for Endocrinology, Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
    J Clin Endocrinol Metab 87:2857-62. 2002
  4. ncbi request reprint Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men
    Vincenzo Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41100 Modena, Italy
    Mol Cell Endocrinol 193:19-28. 2002
  5. ncbi request reprint Sex steroids and sexual desire mechanism
    V Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Modena, Italy
    J Endocrinol Invest 26:29-36. 2003
  6. ncbi request reprint Bone loss, sex steroids and male age related hypogonadism
    V Rochira
    Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Policlinico, 41100 Modena, Italy
    J Endocrinol Invest 28:46-8. 2005
  7. doi request reprint The effects of long-term raloxifene and estradiol treatments on bone in a patient with congenital aromatase deficiency
    L Zirilli
    Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Via Giardini 1355, 41100 Modena, Italy
    Bone 45:827-32. 2009
  8. ncbi request reprint Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho)physiology
    V Rochira
    Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
    Eur J Endocrinol 154:175-85. 2006
  9. ncbi request reprint Oestradiol replacement treatment and glucose homeostasis in two men with congenital aromatase deficiency: evidence for a role of oestradiol and sex steroids imbalance on insulin sensitivity in men
    V Rochira
    Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Italy
    Diabet Med 24:1491-5. 2007
  10. ncbi request reprint Bilateral osteonecrosis of the femoral head in an adult man affected by congenital estrogen deficiency
    A Balestrieri
    Department of Internal Medicine, Chair of Endocrinology, University of Modena and Reggio Emilia, Policlinico, Modena, Italy
    J Endocrinol Invest 26:762-4. 2003

Collaborators

  • Cesare Carani
  • P J Meunier
  • Paolo Beck-Peccoz
  • G Guaraldi
  • Gianluca Aimaretti
  • Colin D Clyne
  • Susan Davis
  • L Zirilli
  • Lucia Zirilli
  • Laura Maffei
  • Elisa Pignatti
  • C Diazzi
  • Fabio Lanfranco
  • Giovanni Caffagni
  • Chiara Diazzi
  • Bruno Madeo
  • Claudio Aranda
  • Evan R Simpson
  • A Balestrieri
  • L Roncucci
  • P Benatti
  • P Chavassieux
  • G Rossi
  • L Maffei
  • M Ponz de Leon
  • S Romano
  • G Orlando
  • Matteo Baldi
  • Ginevra Corneli
  • N Squillace
  • Ezio Ghigo
  • Maria L Simone
  • Bibiana Fabre
  • Paula Antunez
  • Alessia Sanguanini
  • Souheir Houssami
  • Gloria Tubert
  • Yoko Murata
  • Marcela Vazquez
  • L Baldini
  • B Madeo

Detail Information

Publications22

  1. ncbi request reprint Congenital estrogen deficiency: in search of the estrogen role in human male reproduction
    V Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Via del Pozzo 71, Policlinico, 41100, Modena, Italy
    Mol Cell Endocrinol 178:107-15. 2001
    ....
  2. ncbi request reprint Role of estrogen on bone in the human male: insights from the natural models of congenital estrogen deficiency
    V Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41100, Modena, Italy
    Mol Cell Endocrinol 178:215-20. 2001
    ..In addition progress have been made in the treatment of such a rare disease even though further studies are needed to a definitive understanding of this issue...
  3. ncbi request reprint Pituitary function in a man with congenital aromatase deficiency: effect of different doses of transdermal E2 on basal and stimulated pituitary hormones
    Vincenzo Rochira
    Center for Endocrinology, Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
    J Clin Endocrinol Metab 87:2857-62. 2002
    ..Finally, the congenital lack of estrogen activity seems to be associated with a slightly impaired secretion of PRL and TSH, suggesting a possible role of estrogens on the pituitary secretion of these hormones in the human male...
  4. ncbi request reprint Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men
    Vincenzo Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41100 Modena, Italy
    Mol Cell Endocrinol 193:19-28. 2002
    ..Finally, the putative use of estrogen in men and the use of aromatase inhibitors and antiestrogen for male disorders are discussed...
  5. ncbi request reprint Sex steroids and sexual desire mechanism
    V Rochira
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Modena, Italy
    J Endocrinol Invest 26:29-36. 2003
    ....
  6. ncbi request reprint Bone loss, sex steroids and male age related hypogonadism
    V Rochira
    Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Policlinico, 41100 Modena, Italy
    J Endocrinol Invest 28:46-8. 2005
    ..Recently, the study of sex steroids on bone physiology in men has highlighted the central role of estrogens on bone pathophysiology. This review focuses on the relative role of sex steroids on bone loss in aging men...
  7. doi request reprint The effects of long-term raloxifene and estradiol treatments on bone in a patient with congenital aromatase deficiency
    L Zirilli
    Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Via Giardini 1355, 41100 Modena, Italy
    Bone 45:827-32. 2009
    ....
  8. ncbi request reprint Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho)physiology
    V Rochira
    Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
    Eur J Endocrinol 154:175-85. 2006
    ..In particular, the role of sex steroids on bone sexual dimorphism in health and disease has been analyzed...
  9. ncbi request reprint Oestradiol replacement treatment and glucose homeostasis in two men with congenital aromatase deficiency: evidence for a role of oestradiol and sex steroids imbalance on insulin sensitivity in men
    V Rochira
    Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Italy
    Diabet Med 24:1491-5. 2007
    ..To investigate the effects of sex steroids and oestrogen on insulin sensitivity in men, we studied two male adults with aromatase deficiency (subject 1 and subject 2)...
  10. ncbi request reprint Bilateral osteonecrosis of the femoral head in an adult man affected by congenital estrogen deficiency
    A Balestrieri
    Department of Internal Medicine, Chair of Endocrinology, University of Modena and Reggio Emilia, Policlinico, Modena, Italy
    J Endocrinol Invest 26:762-4. 2003
    ..The possibility of development of bone necrosis in patients affected by congenital estrogen deficiency needs to be considered and magnetic resonance imaging can be a useful method for an early detection of this disease...
  11. ncbi request reprint Hypopituitarism and HIV-infection: a new comorbidity in the HAART era?
    L Zirilli
    Chair of Endocrinology, Integrated Department of Medicine, Endocrinology, Metabolism, and Geriatrics, University of Modena and Reggio Emilia, 41100 Modena, Italy
    J Endocrinol Invest 31:33-8. 2008
    ....
  12. doi request reprint Differentiated thyroid carcinoma (DTC) in a young woman with Peutz-Jeghers syndrome: are these two conditions associated?
    L Zirilli
    Integrated Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Ospedale S Agostino Estense di Baggiovara, Via Giardini 1355, Baggiovara, Modena, Italy
    Exp Clin Endocrinol Diabetes 117:234-9. 2009
    ..Differentiated thyroid cancers (DTCs) present mainly as sporadic, but they may have also a familial component. We present a case of PJS in a caucasian 25 years-old woman, who developed a DTC...
  13. doi request reprint A novel mutation in the human aromatase gene: insights on the relationship among serum estradiol, longitudinal growth and bone mineral density in an adult man under estrogen replacement treatment
    Fabio Lanfranco
    Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Italy
    Bone 43:628-35. 2008
    ....
  14. pmc The osteoporotic male: overlooked and undermanaged?
    Bruno Madeo
    Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Ospedale S Agostino Estense di Baggiovara, Modena, Italy
    Clin Interv Aging 2:305-12. 2007
    ..This review focuses on the clinical approach and treatment strategy for osteoporosis in men with particular attention to its relationship with male hypogonadism...
  15. ncbi request reprint A novel compound heterozygous mutation of the aromatase gene in an adult man: reinforced evidence on the relationship between congenital oestrogen deficiency, adiposity and the metabolic syndrome
    Laura Maffei
    Consultorios Asociados de Endocrinologia Buenos Aires, Argentina
    Clin Endocrinol (Oxf) 67:218-24. 2007
    ..Descriptions of new cases of human aromatase deficiency are useful for a better understanding of male oestrogen pathophysiology, as some aspects remain controversial...
  16. ncbi request reprint Skeletal effects of long-term estrogen and testosterone replacement treatment in a man with congenital aromatase deficiency: evidences of a priming effect of estrogen for sex steroids action on bone
    Vincenzo Rochira
    Department of Medicine, University of Modena and Reggio Emilia, Ospedale S Agostino Estense di Baggiovara, Via Giardini 1355, Baggiovara, 41100 Modena, Italy
    Bone 40:1662-8. 2007
    ..Only the combined treatment led to optimal parameters of aBMD suggesting that testosterone needs estrogens as a permissive factor for a direct androgen anabolic action on bone in men...
  17. ncbi request reprint Hypothalamic-pituitary-gonadal axis in two men with aromatase deficiency: evidence that circulating estrogens are required at the hypothalamic level for the integrity of gonadotropin negative feedback
    Vincenzo Rochira
    Integrated Department of Medicine, Endocrinology, Metabolism and Geriatrics, University of Modena and Reggio Emilia, Modena, Italy
    Eur J Endocrinol 155:513-22. 2006
    ....
  18. ncbi request reprint Sex steroids and sexual desire in a man with a novel mutation of aromatase gene and hypogonadism
    Cesare Carani
    Department of Internal Medicine, University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy
    Psychoneuroendocrinology 30:413-7. 2005
    ..Sexual behavior is mainly under the control of cognitive functions in men, but sex steroids may modulate some aspects of male sexuality. Our findings suggest that in men estrogens could play a role in sexual activity...
  19. ncbi request reprint Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment
    Laura Maffei
    Consultorios Asociados de Endocrinologia, 1425 Buenos Aires, Argentina
    J Clin Endocrinol Metab 89:61-70. 2004
    ..This new case of aromatase deficiency confirms previous data on bone maturation and mineralization, and it reveals a high risk for the precocious development of cardiovascular disease in young aromatase-deficient men...
  20. doi request reprint Human models of aromatase deficiency
    Lucia Zirilli
    Integrated Department of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Via Giardini 1355, 41100 Modena, Italy
    J Steroid Biochem Mol Biol 109:212-8. 2008
    ..Moreover, the increasing knowledge on the role of estrogen in several metabolic pathways could be important for a better management of several metabolic diseases...
  21. ncbi request reprint Sildenafil improves sleep-related erections in hypogonadal men: evidence from a randomized, placebo-controlled, crossover study of a synergic role for both testosterone and sildenafil on penile erections
    Vincenzo Rochira
    Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy
    J Androl 27:165-75. 2006
    ..Furthermore, these data strongly support the idea of a synergic effect on sleep-related erections of sildenafil and testosterone...
  22. ncbi request reprint Estrogens in males: what have we learned in the last 10 years?
    Vincenzo Rochira
    Integrated Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Modena 41100, Italy
    Asian J Androl 7:3-20. 2005
    ..The continuing increase in data obtained, and recent discoveries in this area will enable a better understanding of male physiology; these, in turn, will have important clinical implications...