D Roccatello

Summary

Affiliation: University of Turin
Country: Italy

Publications

  1. ncbi Long-term effects of anti-CD20 monoclonal antibody treatment of cryoglobulinaemic glomerulonephritis
    Dario Roccatello
    Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica CMID, P zza del Donatore di Sangue 3, 10152 Torino, Italy
    Nephrol Dial Transplant 19:3054-61. 2004
  2. ncbi Effects of anti-CD20 monoclonal antibody as a rescue treatment for ANCA-associated idiopathic systemic vasculitis with or without overt renal involvement
    D Roccatello
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale S G Bosco, Torino, Italy
    Clin Exp Rheumatol 26:S67-71. 2008
  3. doi Long-term effects of methylprednisolone pulses and mycophenolate mofetil in IgA nephropathy patients at risk of progression
    Dario Roccatello
    Center for Immunopathology and Rare Diseases, Department of Rare, Immunologic, Haematologic and Immunohaematologic Diseases, San G Bosco Hospital and University of Turin, Turin, Italy
    J Nephrol 25:198-203. 2012
  4. ncbi [The role of rituximab in the treatment of ANCA-associated systemic vasculitis]
    Dario Roccatello
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Ospedale G Bosco e Universita di Torino, Torino, Italy
    G Ital Nefrol 28:474-88. 2011
  5. doi Intensive short-term treatment with rituximab, cyclophosphamide and methylprednisolone pulses induces remission in severe cases of SLE with nephritis and avoids further immunosuppressive maintenance therapy
    Dario Roccatello
    Universita di Torino, Torino, Italy
    Nephrol Dial Transplant 26:3987-92. 2011
  6. ncbi Relationship between cryoglobulinemia-associated nephritis and HCV infection
    Dario Roccatello
    Dipartimento di Medicina e Oncologia Sperimentale, Sezione di Patologia Clinica, , Ospedale Emergenza Torino Nord San G Bosco, L go Donatore del Sangue 3, 10154 Torino, Italy
    Expert Rev Clin Immunol 4:515-24. 2008
  7. ncbi [Antiphospholipid syndrome and kidney]
    D Roccatello
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale San Giovanni Bosco, ASL 4, Torino
    G Ital Nefrol 24:111-20. 2007
  8. ncbi Multicenter study on hepatitis C virus-related cryoglobulinemic glomerulonephritis
    Dario Roccatello
    Centro Universitario di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Ospedale S G Bosco, Torino, Italy
    Am J Kidney Dis 49:69-82. 2007
  9. doi Rituximab as a therapeutic tool in severe mixed cryoglobulinemia
    Dario Roccatello
    Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica CMID, Ospedale S G Bosco, L go Donatore del Sangue 3, 10154, Torino, Italy
    Clin Rev Allergy Immunol 34:111-7. 2008
  10. doi Anti-neuronal antibodies in patients with HCV-related mixed cryoglobulinemia
    M Alpa
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare CMID, Struttura Complessa Direzione Universitaria di Immunologia Clinica, Ospedale San Giovanni Bosco, Universita di Torino, Italy
    Autoimmun Rev 8:56-8. 2008

Collaborators

Detail Information

Publications29

  1. ncbi Long-term effects of anti-CD20 monoclonal antibody treatment of cryoglobulinaemic glomerulonephritis
    Dario Roccatello
    Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica CMID, P zza del Donatore di Sangue 3, 10152 Torino, Italy
    Nephrol Dial Transplant 19:3054-61. 2004
    ..Similar effects could be expected in type II MC...
  2. ncbi Effects of anti-CD20 monoclonal antibody as a rescue treatment for ANCA-associated idiopathic systemic vasculitis with or without overt renal involvement
    D Roccatello
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale S G Bosco, Torino, Italy
    Clin Exp Rheumatol 26:S67-71. 2008
    ..The key mechanism of action of CYC is suppression of the B lymphocyte activity. However, a considerable minority of patients either remains refractory to conventional therapy or experiences dose-limiting side effects...
  3. doi Long-term effects of methylprednisolone pulses and mycophenolate mofetil in IgA nephropathy patients at risk of progression
    Dario Roccatello
    Center for Immunopathology and Rare Diseases, Department of Rare, Immunologic, Haematologic and Immunohaematologic Diseases, San G Bosco Hospital and University of Turin, Turin, Italy
    J Nephrol 25:198-203. 2012
    ..Some histologic lesions are irreversible and progress toward obliteration of glomerular capillaries. Others are acute inflammatory processes potentially susceptible to reversal by means of immunosuppressive therapies...
  4. ncbi [The role of rituximab in the treatment of ANCA-associated systemic vasculitis]
    Dario Roccatello
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Ospedale G Bosco e Universita di Torino, Torino, Italy
    G Ital Nefrol 28:474-88. 2011
    ..A small number of cases of progressive multifocal leukoencephalopathy reported in patients receiving rituximab in off-label use (albeit none with ANCA-associated vasculitis) highlights the importance of pharmacovigilance...
  5. doi Intensive short-term treatment with rituximab, cyclophosphamide and methylprednisolone pulses induces remission in severe cases of SLE with nephritis and avoids further immunosuppressive maintenance therapy
    Dario Roccatello
    Universita di Torino, Torino, Italy
    Nephrol Dial Transplant 26:3987-92. 2011
    ..Rituximab is expected to induce apoptosis of all the CD20-positive B cells. A proportion of patients are refractory or intolerant to standard immunosuppression. These are candidate to new therapeutic options...
  6. ncbi Relationship between cryoglobulinemia-associated nephritis and HCV infection
    Dario Roccatello
    Dipartimento di Medicina e Oncologia Sperimentale, Sezione di Patologia Clinica, , Ospedale Emergenza Torino Nord San G Bosco, L go Donatore del Sangue 3, 10154 Torino, Italy
    Expert Rev Clin Immunol 4:515-24. 2008
    ....
  7. ncbi [Antiphospholipid syndrome and kidney]
    D Roccatello
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale San Giovanni Bosco, ASL 4, Torino
    G Ital Nefrol 24:111-20. 2007
    ..Anticoagulation is the therapy of choice, especially in arterial stenosis and acute disease, but is probably also indicated in chronic and subacute patterns. The role of immunomodulatory therapy has to be assessed...
  8. ncbi Multicenter study on hepatitis C virus-related cryoglobulinemic glomerulonephritis
    Dario Roccatello
    Centro Universitario di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Ospedale S G Bosco, Torino, Italy
    Am J Kidney Dis 49:69-82. 2007
    ..Mixed cryoglobulinemia is a multisystem disorder associated strongly with hepatitis C virus (HCV) infection. The kidney frequently is involved, and glomerulonephritis represents the key factor affecting prognosis...
  9. doi Rituximab as a therapeutic tool in severe mixed cryoglobulinemia
    Dario Roccatello
    Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica CMID, Ospedale S G Bosco, L go Donatore del Sangue 3, 10154, Torino, Italy
    Clin Rev Allergy Immunol 34:111-7. 2008
    ..Based on this experience and a number of reports published in the last 5 years, Rituximab appears to be a safe and effective therapeutic option in symptomatic patients with HCV-associated MC with signs of systemic vasculitis...
  10. doi Anti-neuronal antibodies in patients with HCV-related mixed cryoglobulinemia
    M Alpa
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare CMID, Struttura Complessa Direzione Universitaria di Immunologia Clinica, Ospedale San Giovanni Bosco, Universita di Torino, Italy
    Autoimmun Rev 8:56-8. 2008
    ..Anti-neuronal reactivity could be a direct trigger of neurologic injury in this disorder...
  11. ncbi Anti-GM1 and anti-sulfatide antibodies in patients with systemic lupus erythematosus, Sjögren's syndrome, mixed cryoglobulinemia and idiopathic systemic vasculitis
    M Alpa
    Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa Direzione Universitaria di Immunologia Clinica, Universita di Torino, Torino, Italy
    Clin Exp Rheumatol 25:556-62. 2007
    ..The possible appearance of these autoantibodies in systemic diseases that are not limited to the nervous system has not been fully addressed yet...
  12. doi Kidney biopsy in pregnancy: evidence for counselling? A systematic narrative review
    G B Piccoli
    Struttura Semplice of Nephrology, Department of Clinical and Biological Sciences, University of Torino, Turin, Italy
    BJOG 120:412-27. 2013
    ..Use of kidney biopsy is controversial, but a systematic review has not been carried out to date...
  13. doi Thrombotic recurrences and bleeding events in APS vascular patients: a review from the literature and a comparison with the APS Piedmont Cohort
    M Bazzan
    Haematology and Thrombosis Unit, Department of Rare, Immunologic, Hematologic Diseases and Transfusion Medicine, Giovanni Bosco Hospital, Turin, Italy
    Autoimmun Rev 12:826-31. 2013
    ..Moreover, there are evidences that high risk (mainly for aPL profile) APS vascular patients have a high recurrence rate in spite of correct OAT treatment. Clinical trials in this clinical setting are needed...
  14. ncbi Prevention of thrombosis relapse in antiphospholipid syndrome patients refractory to conventional therapy using intravenous immunoglobulin
    S Sciascia
    Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale Torino Nord Emergenza San G Bosco ed Università di Torino, Italy
    Clin Exp Rheumatol 30:409-13. 2012
    ..To investigate the long-term effects of megadoses of intravenous immunoglobulin (IVIG) in a small cohort of patients with relapsing primary APS resistant to conventional treatments...
  15. ncbi Structural and functional properties of proteasomes purified from the human kidney
    Simone Baldovino
    CMID, Centro Universitario Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Giovanni Bosco Hospital, Turin, Italy
    J Nephrol 19:710-6. 2006
    ..This process is enhanced when the proteasome is associated with the polymeric protein 11S regulator/PA28 made up of 4 alfa and 3 beta subunits...
  16. ncbi Parvovirus B19 and immune disorders
    Agostino Pugliese
    Department of Medical and Surgical Sciences, Clinical Microbiology University of Turin, Amedeo di Savoia Hospital, Turin, Italy
    Cell Biochem Funct 25:639-41. 2007
    ..In fact, most of our patients were affected by a nephropathic or systemic form of HCV+ cryoglobulinemia and the presence of other infective cofactors could be suggestive in the evolution of this clinical situation...
  17. pmc Genetic factors associated with rheumatoid arthritis and systemic vasculitis: Evaluation of a panel of polymorphisms
    Elisa Menegatti
    Department of Experimental Medicine and Oncology, University of Turin, Italy
    Dis Markers 27:217-23. 2009
    ..02) coupled with an increase in homozygous c.-1837CC in the NF-kappaB2 gene (p=0.02). Our data suggest that genetic variation in UG and NF-kappaB2 pathways could have effects in connective tissue disease susceptibility...
  18. doi Rituximab in cryoglobulinemic peripheral neuropathy
    Roberto Cavallo
    SC Neurologia, Ospedale San Giovanni Bosco, Turin, Italy
    J Neurol 256:1076-82. 2009
    ..Viral load did not significantly change. Side effects were negligible. In this open prospective study, rituximab appeared to be effective and safe in the treatment of patients with type II cryoglobulinemia-associated neuropathy...
  19. doi Clinical accuracy for diagnosis of antiphospholipid syndrome in systemic lupus erythematosus: evaluation of 23 possible combinations of antiphospholipid antibody specificities
    S Sciascia
    Lupus Research Unit, The Rayne Institute, Division of Women s Health, King s College London, London, UK
    J Thromb Haemost 10:2512-8. 2012
    ....
  20. doi Systemic lupus erythematosus and infections: clinical importance of conventional and upcoming biomarkers
    S Sciascia
    Lupus Research Unit, The Rayne Institute, Division of Women s Health, King s College London, UK
    Autoimmun Rev 12:157-63. 2012
    ..We reviewed the literature on the available tests to discriminate between SLE activity and infections, focusing on conventional and upcoming biomarkers...
  21. doi NEMO syndrome (incontinentia pigmenti) and systemic lupus erythematosus: a new disease association
    G B Piccoli
    Nephrology Unit, Department of Clinical and Biological Sciences, San Luigi Hospital, Orbassano, University of Turin, Turin, Italy
    Lupus 21:675-81. 2012
    ..This report may suggest a role for NF-kB essential modulator in the pathogenesis of SLE, in the context of the complex immunologic deficiencies increasingly associated with autoimmune diseases...
  22. doi Migraineurs show a high prevalence of antiphospholipid antibodies
    C Cavestro
    S Lazzaro Hospital, Headache Center, Alba, Turin, Italy
    J Thromb Haemost 9:1350-4. 2011
    ..It has been observed that migraineurs show a higher risk of thrombosis and that the most frequent symptom reported by patients with antiphospholipid syndrome is headache, especially migraine...
  23. pmc Mycophenolate mofetil and roscovitine decrease cyclin expression and increase p27(kip1) expression in anti Thy1 mesangial proliferative nephritis
    M Chiara
    Cattedre e Scuola di Specializzazione di Patologia Clinica, Universita di Torino, Torino, Italy
    Clin Exp Immunol 139:225-35. 2005
    ..Immunohistochemical evaluation of p27(kip1) aimed to examine the influence of MMF or R on protein expression confirmed up-regulation...
  24. ncbi Progressive multifocal leukoencephalopathy during cyclosporine treatment. A case report
    S Gentile
    Divisione di Neurologia, Ospedale Giovanni Bosco, Torino, Italy
    Ital J Neurol Sci 17:363-6. 1996
    ..Progressive multifocal leukoencephalopathy was diagnosed. The literature contains only one report of an analogous case observed during a course of cyclosporine treatment for Wegener's granulomatosis...
  25. ncbi Polymorphism of the uteroglobin gene in systemic lupus erythematosus and IgA nephropathy
    Elisa Menegatti
    Dipartimento di Medicina e Oncologia Sperimentale, Cattedre di Patologia Clinica, Universita di Torino, Italy
    Lab Invest 82:543-6. 2002
    ..Although the significance of any alterations in the UG exon 1 noncoding region in humans has yet to be clarified, initial evidence suggests that it may alter the control of immune response and of inflammation...
  26. ncbi Nail fold videocapillaroscopy in mixed cryoglobulinaemia
    Daniela Rossi
    Cattedra di Patologia Clinica, Universita di Torino, e Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare a Direzione Universitaria, ASL4, Piazza Donatore di sangue 3, 10154 Turin, Italy
    Nephrol Dial Transplant 19:2245-9. 2004
    ..The nutritional circulation that depends on tissue capillaries, can be expected to be significantly impacted in mixed cryoglobulinaemia (MC)...
  27. ncbi Thin glomerular basement membrane disease: clinical significance of a morphological diagnosis--a collaborative study of the Italian Renal Immunopathology Group
    Giovanni M Frascà
    Nephrology, Dialysis and Renal Transplantation Unit, St Orsola University Hospital, V Massarenti 9, 40137 Bologna, Italy
    Nephrol Dial Transplant 20:545-51. 2005
    ..This study investigated 51 patients with the morphological diagnosis of TBMD lacking any sign of ATS, with the aim of defining the prevalence of type IV collagen mutations and the course of the disease...
  28. ncbi The Italian Registry for Therapeutic Apheresis. A report from the Apheresis Study Group of the Italian Society of Nephrology
    Stefano Passalacqua
    Nephrology Department, C I Columbus UCSC, Rome, Italy
    J Clin Apher 20:101-6. 2005
    ....
  29. doi Minocycline in combination with mycophenolate mofetil in oral mucous membrane pemphigoid
    Marco Carrozzo
    Eur J Dermatol 18:198-200. 2008