Research Topics
| Mario RizzettoSummaryAffiliation: University of Turin Country: Italy Publications
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Detail Information
Publications
Prompt relapse of viremia after lamivudine discontinuation in e-minus chronic hepatitis B patients completely responders during 5 years of therapyValeria Barbon
J Hepatol 41:500-1. 2004
Current management of delta hepatitisMario Rizzetto
Division of Gastroenterology, University of Torino, Torino, Italy
Liver Int 33:195-7. 2013..Although the end-point of therapy is the clearance of the HBsAg, this is seldom achieved. Current management of HDV patients is based on standard practices which should be pragmatic and individualized...
Epidemiology of hepatitis DMario Rizzetto
Division of Gastroenterology, University of Torino, Turin, Italy
Semin Liver Dis 32:211-9. 2012..Hepatitis D continues to ravage populations of developing and poor countries where HBV remains unchecked; action is needed to enforce HBV vaccination as effective prophylaxis not only against HBV, but against HDV as well...
Hepatitis D: clinical features and therapyMario Rizzetto
Department of Gastroenterology, Molinette, University of Torino, Torino, Italy
Dig Dis 28:139-43. 2010..The problem is formidable as HDV has no enzymatic protein to be targeted by conventional antiviral therapy. A potential target of therapy is offered by the process of hepatitis D virion assembly...
Hepatitis D: the comeback?Mario Rizzetto
Department of Gastroenterology, University of Turin, Turin, Italy
Liver Int 29:140-2. 2009..Hepatitis D remains an important health problem outside Europe, and new foci of infection continue to be identified in developing countries...
Hepatitis D: thirty years afterMario Rizzetto
Division of Gastroenterology, Molinette University of Turin, Corso Bramante, Turin 10126, Italy
J Hepatol 50:1043-50. 2009..3) The search for a therapy for chronic hepatitis D (CHD). This review summarizes the progress achieved in each field of research in the thirty years that have passed since the discovery of HDV...
Chronic HBV-related liver diseaseMario Rizzetto
Gastrohepatology Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy
Mol Aspects Med 29:72-84. 2008....
Incidence of type 2 diabetes mellitus and glucose abnormalities in patients with chronic hepatitis C infection by response to treatment: results of a cohort studyChiara Giordanino
Gastroenterology, Molinette Hospital, Turin, Italy
Am J Gastroenterol 103:2481-7. 2008..Patients with chronic hepatitis C are at risk of developing type 2 diabetes mellitus (DM) and impaired fasting glucose (IFG), and this risk may increase among hepatitis C virus (HCV) patients not responding to an antiviral therapy...
Viral load at the time of liver transplantation and risk of hepatitis B virus recurrenceAlfredo Marzano
Department of Gastroenterology, San Giovanni Battista Hospital, Turin, Italy
Liver Transpl 11:402-9. 2005..0003). In conclusion, spontaneous or antiviral-induced HBV DNA viral load at the time of surgery classifies the risk of HBV recurrence after liver transplantation and indicates the best prophylaxis strategy...
Hypoadiponectinemia predicts the severity of hepatic fibrosis and pancreatic Beta-cell dysfunction in nondiabetic nonobese patients with nonalcoholic steatohepatitisGiovanni Musso
Department of Internal Medicine, University of Turin, Italy
Am J Gastroenterol 100:2438-46. 2005..Our findings provide further rationale for therapeutic approaches aimed at increasing adiponectin levels together with restoring beta-cell function and insulin sensitivity...
Is serum uric acid a predictive factor of response to IFN-treatment in patients with chronic hepatitis C infection?Rinaldo Pellicano
Department of Gastro Hepatology, San Giovanni Battista Molinette Hospital, Torino, Italy
J Med Virol 80:628-31. 2008..49; 95% CI: 0.28-0.85). Serum uric acid level > or =5.8 mg/dl is predictive of poor response to HCV treatment. Prospective studies are needed to clarify the issue...
Type 2 diabetes mellitus and chronic hepatitis C: which is worse? Results of a long-term retrospective cohort studyChiara Giordanino
Division of Gastroenterology, University of Turin, San Luigi Medical School, Orbassano, Italy
Dig Liver Dis 44:406-12. 2012....
A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver diseaseElisabetta Bugianesi
Department of Gastroenterology, University of Turin, Italy
Am J Gastroenterol 100:1082-90. 2005..Limited histological data support an association between improved aminotransferases and biopsy findings, which require confirmation in a double-blind trial with appropriate statistical power based on liver histology...
Long-term follow-up of previous hepatitis C virus positive nonresponders to interferon monotherapy successfully retreated with combination therapy: are they really cured?Alessia Ciancio
Dipartimento di Gastroenterologia, Ospedale Molinette, Torino, Italy
Am J Gastroenterol 101:1811-6. 2006....
The first one thousand liver transplants in Turin: a single-center experience in ItalyMauro Salizzoni
Liver Transplantation Center, San Giovanni Battista Hospital, Turin, Italy
Transpl Int 18:1328-35. 2005..76% at 5 years respectively). Increasing experience in liver transplant surgery and postoperative care allowed standardization of the procedure and expansion of the activity, with parallel improvement of the results...
The natural history of gastrointestinal subepithelial tumors arising from muscularis propria: an endoscopic ultrasound surveyMauro Bruno
Department of Gastro Hepatology, Molinette Hospital, Torino, Italy
J Clin Gastroenterol 43:821-5. 2009..Aim of this study was to evaluate the natural course of benign-appearing lesions originating from muscularis propria in organs where GISTs significantly overcome leiomyomas...
Prophylaxis of hepatitis B virus recurrence after liver transplantation in carriers of lamivudine-resistant mutantsAlfredo Marzano
Department of Gastroenterology, San Giovanni Battista Hospital, Turin, Italy
Liver Transpl 11:532-8. 2005....
Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis CEster Vanni
Division of Gastro Hepatology, San Giovanni Battista Hospital, University of Turin, Turin, Italy
Hepatology 50:697-706. 2009..Substrate competition by increased lipid oxidation and possibly enhanced hepatic expression of inflammatory cytokines/mediators could be involved in the defective glucose regulation...
Prevention of paracentesis-induced circulatory dysfunction in cirrhosis: standard vs half albumin doses. A prospective, randomized, unblinded pilot studyCarlo Alessandria
Division of Gastroenterology and Hepatology, San Giovanni Battista Hospital University of Turin, Turin, Italy
Dig Liver Dis 43:881-6. 2011..Albumin infusion (8g of albumin/L of ascites removed) is effective in preventing it, but high costs and scant availability limit its use...
Ectopic liver and hepatocarcinogenesis: report of three cases with four years' follow-upNicola Leone
Department of Gastroenterology, Division of B Surgery and First Service of Human Pathology, Molinette Hospital, Turin, Italy
Eur J Gastroenterol Hepatol 16:731-5. 2004..The patients were followed up for 4 years after surgery: two remain free of disease, suggesting that the unique localisation and growth pattern may render these tumours particularly susceptible to curative resection...
Inosine triphosphatase polymorphisms and ribavirin pharmacokinetics as determinants of ribavirin-associate anemia in patients receiving standard anti-HCV treatmentAntonio DʼAvolio
Department of Infectious Diseases, University of Turin, Amedeo di Savoia Hospital, Italy
Ther Drug Monit 34:165-70. 2012..However, no definitive data are yet available on the role of plasma RBV concentrations on hemoglobin (Hb) decrement. Moreover, no data have been published on the possible interplay between these 2 factors...
Pegylated interferon alpha-2b as monotherapy or in combination with ribavirin in chronic hepatitis deltaGrazia Anna Niro
Gastroenterology CSS Hospital, S Giovanni Rotondo, and Gastroenterology Molinette Hospital and Unversity, Turin, Italy
Hepatology 44:713-20. 2006..Overall tolerance of therapy was poor...
A randomized 4-arm multicenter study of interferon alfa-2b plus ribavirin in the treatment of patients with chronic hepatitis C relapsing after interferon monotherapyGiorgio Saracco
Dipartimento di Gastroenterologia, Ospedale Molinette, Torino, Italy
Hepatology 36:959-66. 2002....
Fatal multiple systemic embolisms after injection of cyanoacrylate in bleeding gastric varices of a patient who was noncirrhotic but with idiopathic portal hypertensionGiorgio Saracco
Department of Gastroenterology, Molinette Hospital, Torino, Itlay
Gastrointest Endosc 65:345-7. 2007
The practice of percutaneous liver biopsy in a gastrohepatology day hospital: a retrospective study on 835 biopsiesGiovanni Clemente Actis
Department of Gastro Hepatology and Clinical Nutrition, San Giovanni Battista Molinette Hospital, Torino, 10126, Italy
Dig Dis Sci 52:2576-9. 2007..In conclusion, these data accord with indications expressed by international guidelines. The impact of liver biopsy on therapeutic decision-making needs to be studied further...
Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liverElisabetta Bugianesi
Division of Gastro Hepatology, Department of Internal Medicine, University of Turin, Turin, Italy
Hepatology 39:179-87. 2004..Increased ferritin levels are markers of severe histologic damage, but not of iron overload. Iron burden and HFE mutations do not contribute significantly to hepatic fibrosis in the majority of patients with NAFLD...
The 17-year single-center experience with the use of azathioprine to maintain remission in ulcerative colitisGiovanni C Actis
Department of Digestive Disease and Nutrition, Ospedale Molinette, c so Bramante 88, Torino, Italy
Biomed Pharmacother 63:362-5. 2009..By contrast, the toxicity rates were higher than expected. Failure to genotype or to use escalating AZA doses can only be hypothesized as causes...
Transcatheter arterial chemoembolization for hepatocellular carcinoma in cirrhosis: influence on portal hypertensionChiara Elia
Department of Gastrohepatology, San Giovanni Battista Hospital, Corso Bramante 88, Turin, Italy
Eur J Gastroenterol Hepatol 23:573-7. 2011..We also prospectively evaluated portal pressure by hepatic venous portal gradient (HVPG) before and within 3 days by TACE in a group of 15 patients...
Prevalence of Helicobacter pylori infection and intestinal metaplasia in subjects who had undergone surgery for gastric adenocarcinoma in Northwest ItalyGiorgio Palestro
Department of Oncology, University of Torino, 10126 Torino, Italy
World J Gastroenterol 11:7131-5. 2005....
Occult hepatitis B virus infection in HBsAg negative patients undergoing liver transplantation: clinical significanceValeria Ghisetti
Laboratory of Microbiology, Molinette Hospital, Turin, Italy
Liver Transpl 10:356-62. 2004....
Outcome of chronic delta hepatitis in Italy: a long-term cohort studyGrazia Anna Niro
Division of Gastroenterology, Casa Sollievo Sofferenza Hospital, IRCCS, San Giovanni, Rotondo, Italy
J Hepatol 53:834-40. 2010..To investigate the impact of HDV infection on morbidity and mortality of patients...
Negative predictive value of IL28B, SLC28A2, and CYP27B1 SNPs and low RBV plasma exposure for therapeutic response to PEG/IFN-RBV treatmentAntonio D'Avolio
Unit of Infectious Diseases, University of Turin, Department of Medical Sciences, Amedeo di Savoia Hospital, Turin, Italy
Ther Drug Monit 34:722-8. 2012..The aim of our study was to carry out an integrated analysis of the effects of polymorphisms and ribavirin (RBV) plasma exposure on outcome...
Reliability of transient elastography for the detection of fibrosis in non-alcoholic fatty liver disease and chronic viral hepatitisSilvia Gaia
San Giovanni Battista Hospital, Gastroenterology, C Bramante 88 10128, Italy
J Hepatol 54:64-71. 2011....
Fibrosis in genotype 3 chronic hepatitis C and nonalcoholic fatty liver disease: Role of insulin resistance and hepatic steatosisElisabetta Bugianesi
Gastroenterology Department, University of Turin, Italy
Hepatology 44:1648-55. 2006..Virus-induced hepatic steatosis as seen in CHC-3 does not contribute significantly to liver fibrosis...
Preliminary experience with a new cytology brush in EUS-guided FNAMauro Bruno
Department of Gastro Hepatology, Molinette Hospital, Torino, Italy
Gastrointest Endosc 70:1220-4. 2009..Recently, the EchoBrush (Cook Endoscopy, Winston-Salem, NC), a disposable cytologic brush, was introduced to the market. To date, only 1 study, limited to 10 pancreatic cyst cases, using this device has been published...
Ectopic livers and related pathology: report of three cases of benign lesionsNicola Leone
Department of Gastroenterology, Molinette Hospital, Turin, Italy
Dig Dis Sci 50:1818-22. 2005
Effects of long-term Irbesartan in reducing portal pressure in cirrhotic patients: comparison with propranolol in a randomised controlled studyWilma Debernardi Venon
Department of Gastroenterology, Ospedale Molinette, S Giovanni Battista Hospital, c so Bramante 88, 10126, Turin, Italy
J Hepatol 38:455-60. 2003..We tested the efficacy of Irbesartan (Irb) vs. Propranolol (Pro) in reducing portal pressure and evaluated its systemic haemodynamic effects...
Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severityElisabetta Bugianesi
Division of Gastroenterology, University of Turin, Ospedale San Giovanni Battista, Corso Bramante 88, I 10126 Torino, Italy
J Clin Endocrinol Metab 90:3498-504. 2005..Hypoadiponectinemia in NAFLD is part of a metabolic disturbance characterized by ectopic fat accumulation in the central compartment...
Occult hepatitis B virus infection in patients with chronic hepatitis C treated with antiviral therapyGian Paolo Caviglia
Department of Internal Medicine, University of Turin, Turin, Italy
Hepat Mon 12:e7292. 2012..The impact of OBI in patients with chronic hepatitis C (CHC) is still unclear...
Pancreatic cancer imaging: the new role of endoscopic ultrasoundClaudio De Angelis
Gastrohepatology Department, San Giovanni Battista Hospital, University of Turin Turin, Italy
JOP 8:85-97. 2007..In the near future, there will be great opportunities for the development of diagnostic and therapeutic EUS and pancreatic cancer could be the best testing ground...
Evidence of acute primary occult hepatitis B virus infection in an Italian repeat blood donorPaola Manzini
SCDO SIMT Banca del Sangue and SCDU Gastro epatologia, AOU S Giovanni Battista, Corso Bramante 88, Turin, Italy
Transfusion 49:757-64. 2009..Preliminary evidence of cases of acute occult hepatitis B virus (HBV) infection (OBI) has been recently reported in the literature. Furthermore, OBI definition has been the object of an international consensus conference...
Application of the model for end-stage liver disease score for transjugular intrahepatic portosystemic shunt in cirrhotic patients with refractory ascites and renal impairmentCarlo Alessandria
Department of Gastroenterology and Department of Clinical Nutrition, San Giovanni Battista Hospital, Torino, Italy
Eur J Gastroenterol Hepatol 16:607-12. 2004..Further studies are needed to confirm this finding and ultimately to assess a correction factor to better predict survival after TIPS in patients with functional renal impairment...
Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?Giovanni Sansoè
Gastroenterology Unit, Gradenigo Hospital, Turin, Italy
J Hepatol 43:791-8. 2005..We determined the effects of NEP inhibition by candoxatrilat on hormonal status, liver function and arterial and portal pressures in rats with CCl4-induced cirrhosis...
AT1 receptor antagonist Candesartan in selected cirrhotic patients: effect on portal pressure and liver fibrosis markersWilma Debernardi-Venon
Division of Gastroenterology and Hepatology, S Giovanni Battista Hospital, Turin, Italy
J Hepatol 46:1026-33. 2007..To examine the long-term effects of Candesartan cilexetil, an angiotensin type 1 (AT1) receptor blocker, on portal-systemic haemodynamics and on liver fibrosis...
Lack of association between seroprevalence of Helicobacter pylori infection and primary biliary cirrhosisMarilena Durazzo
Department of Internal Medicine, University of Turin, Corso A M Dogliotti 14, 10126 Turin, Italy
World J Gastroenterol 10:3179-81. 2004..To determine the association between seroprevalence of Helicobacter pylori (H pylori) infection and primary biliary cirrhosis (PBC)...
Helicobacter species and liver diseases: association or causation?Rinaldo Pellicano
Department of Gastro Hepatology, Molinette Hospital, Turin, Italy
Lancet Infect Dis 8:254-60. 2008..More studies are therefore needed to confirm whether a causal association exits between the presence of Helicobacter spp in the liver and the development of cirrhosis and hepatocellular carcinoma...
Antiglycan antibodies as serological markers in the differential diagnosis of inflammatory bowel diseaseDaniele Simondi
Department of Gastrohepatology, San Giovanni Battista Hospital of Turin, Turin, Italy
Inflamm Bowel Dis 14:645-51. 2008..The objective of the study was to evaluate the diagnostic accuracy of recently developed antiglycan serological tests in clinical practice for the diagnosis of Crohn's disease...
Hepatitis B virus reactivation and efficacy of prophylaxis with lamivudine in patients undergoing allogeneic stem cell transplantationLuisa Giaccone
Division of Hematology, SGB Hospital, University of Torino, Torino, Italy
Biol Blood Marrow Transplant 16:809-17. 2010....
Loss of tubuloglomerular feedback in decompensated liver cirrhosis: physiopathological implicationsGiovanni Sansoè
Gradenigo Hospital, Torino, Italy
Dig Dis Sci 50:955-63. 2005....
Re-treatment with interferon-beta of patients with chronic hepatitis C virus infectionRinaldo Pellicano
U.O.A.D.U. Gastro-Hepatology, Hospital S Giovanni Battista (Molinette, Torino, Italy
Eur J Gastroenterol Hepatol 14:1377-82. 2002..However, the results of the trial do not support the use of IFN-beta monotherapy in patients with chronic hepatitis C that is resistant to IFN-alpha...
Prevalence of non-organ-specific autoantibodies in patients suffering from duodenal ulcer with and without Helicobacter pylori infectionRinaldo Pellicano
UOADU Gastro Hepatology, Molinette Hospital, Turin, Italy
Dig Dis Sci 49:395-8. 2004..9%), SMA in 3 of 38 (7.9%), and anti-LKM-1 in 0 patients. The difference was not statistically significant. In this population, H. pylori infection is not associated with an increased prevalence of NOSAs...
Clinical impact of A/H1/N1/09 influenza in patients with cirrhosis: experience from a nosocomial cluster of infectionAlfredo Marzano
Gastro Hepatology Unit, San Giovanni Battista Hospital, University of Turin, Turin, Italy
J Med Virol 85:1-7. 2013..Vaccination, preventive and early treatment and a strict control of nosocomial spread should be activated carefully in patients with cirrhosis during epidemics influenza...
Treatment of hepatitis B e antigen-negative chronic hepatitis B with lamivudineMario Rizzetto
Department of Gastroenterology, University of Turin, Molinette Hospital, Corso Bramante 88, 10125 Turin, Italy
J Hepatol 39:S168-71. 2003
HDV: thirty years laterAntonina Smedile
Gastroenterology and Hepatology Division University of Torino, San Giovanni Battista Hospital, Torino, Italy
Dig Liver Dis 43:S15-8. 2011..Hepatitis D remains a major health problem in many developing areas with outbreaks of the disease continuing to be reported from Asia, Africa and South Africa...
Radiofrequency ablation versus ethanol injection for early hepatocellular carcinoma: A randomized controlled trialFranco Brunello
Divisione di Gastro Epatologia, Ospedale San Giovanni Battista di Torino, Turin, Italy
Scand J Gastroenterol 43:727-35. 2008....
Signal transducers and activators of transcription 3 signaling pathway: an essential mediator of inflammatory bowel disease and other forms of intestinal inflammationAlessandro Musso
Division of Gastroenterology, Ospedale San Giovanni Battista, University of Torino, Torino, Italy
Inflamm Bowel Dis 11:91-8. 2005....
Treatment of recurrent hepatitis C in liver transplants: efficacy of a six versus a twelve month course of interferon alfa 2b with ribavirinBruna Lavezzo
Department of Gastroenterology, Molinette Hospital, C.so Bramante 88, 10126 Turin, Italy
J Hepatol 37:247-52. 2002..CONCLUSIONS: CT is efficacious in controlling HCV disease in about 20% of transplants with recurrent hepatitis C. Six months of therapy are as efficacious as 12 months...
Digestive endoscopy is not a major risk factor for transmitting hepatitis C virusAlessia Ciancio
Ospedale Molinette, Banca del Sangue e del Plasma della città di Torino, Torino, Italy
Ann Intern Med 142:903-9. 2005..The potential role of digestive endoscopy as a mode for transmission of hepatitis C virus (HCV) is controversial...
Serum heat shock protein 27 levels in patients with hepatocellular carcinomaGabriella Gruden
Department of Medical Science, University of Turin, C so AM Dogliotti 14, 10126 Turin, Italy
Cell Stress Chaperones 18:235-41. 2013..5 pg/ml) for differentiating patients with HCC from those with HCC-free chronic liver disease were 70 and 73 %, respectively. In conclusion, sHsp27 levels are enhanced in patients with HCC and may represent a candidate biomarker of HCC...
Sorafenib in hepatocellular carcinoma: prospective study on adverse events, quality of life, and related feasibility under daily conditionsPaola Rita Brunocilla
Division of Gastroenterology and Hepatology, AO San Giovanni Battista, Turin, Italy
Med Oncol 30:345. 2013..3 (range -60.1 to 17.9; P = 0.0003). Treatment withdrawal from adverse events was higher than previously reported, significant QoL decrease occurred, and estimated feasibility was 66.7 %...
Safety and efficacy of endoscopic retrograde cholangiopancreatography in patients with post-liver transplant biliary complications: results of a cohort study with long-term follow-upClaudia Sanna
Department of Gastroenterology, University of Turin, Molinette Hospital, Turin, Italy
Gut Liver 5:328-34. 2011..This study was performed to evaluate the safety and long-term efficacy of ERCP in transplant patients...
Temporary placement of an expandable polyester silicone-covered stent for treatment of refractory benign esophageal stricturesAlessandro Repici
Department of Gastroenterology and Clinical Nutrition, Molinette Hospital, Torino, Italy
Gastrointest Endosc 60:513-9. 2004....
Acute small-bowel perforation secondary to capsule endoscopyAlessandro Repici
Rozzano (Milano, Torino, Italy
Gastrointest Endosc 67:180-3. 2008
Epithelial microchimerism: consistent finding in human liver transplantsSilvia Gaia
Department of Gastroenterology, San Giovanni Battista Hospital, Turin, Italy
J Gastroenterol Hepatol 21:1801-6. 2006....
Insulated-tip knife endoscopic mucosal resection of large colorectal polyps unsuitable for standard polypectomyAlessandro Repici
Department of Gastroenterology, IRCCS Istituto Clinico Humanitas, Milano, Italy
Am J Gastroenterol 102:1617-23. 2007..This study was conducted to evaluate the safety and efficacy in obtaining en bloc resection with It-knife EMR of large colonic lesions not resectable with standard endoscopic techniques...
Clinical and virological response to entecavir in HBV-related chronic hepatitis or cirrhosis: data from the clinical practice in a single-centre cohortAndrea Marengo
Gastro Hepatology Unit, San Giovanni Battista Hospital, University of Turin, Italy
Antivir Ther 18:87-94. 2013....
An aggressive medical approach for inflammatory bowel disease: clinical challenges and therapeutic profiles in a retrospective hospital-based seriesGiovanni C Actis
Division of Gastroenterology, Ospedale Molinette, Torino, Italy
Curr Clin Pharmacol 7:209-13. 2012..We studied the toxicity of cyclosporin (CsA), azathioprine, and mesalamine in 94 patients with inflammatory bowel disease (IBD)...
Detection of serum HDV RNA by RT-PCRAntonina Smedile
Department of Gastroenterology, University of Torino, Azienda Ospedaliera S. Giovanni, Battista, Italy
Methods Mol Med 95:85-93. 2004
Appropriateness of colonoscopy in a digestive endoscopy unit: a prospective study using ASGE guidelinesRenzo Suriani
Department of Gastroenterology, Ospedale degli Infermi, Rivoli, Italy
J Eval Clin Pract 15:41-5. 2009....
Efficacy of lamivudine in HBeAg-negative chronic hepatitis BMario Rizzetto
Department of Gastroenterology, Molinette, University of Torino, Torino, Italy
J Med Virol 66:435-51. 2002..Extended lamivudine treatment beyond 2 years is an option, but further investigation is required to define stopping criteria and the impact of YMDD variants...
Renal failure in cirrhotic patients: role of terlipressin in clinical approach to hepatorenal syndrome type 2Carlo Alessandria
Department of Gastroenterology, San Giovanni Battista Hospital, Torino, Italy
Eur J Gastroenterol Hepatol 14:1363-8. 2002....
Spectral electroencephalogram analysis in hepatic encephalopathy and liver transplantationAlessia Ciancio
Department of Gastroenterology, University of Torino and San Giovanni Battista Hospital, Turin, Italy
Liver Transpl 8:630-5. 2002..The improvement in (S)EEG results observed in transplant recipients confirms the reversibility of bioelectric brain dysfunction with restoration of liver functions...
Capsule enteroscopy vs. other diagnostic procedures in diagnosing obscure gastrointestinal bleeding: a cost-effectiveness studyRiccardo Marmo
Division of Gastroenterology, L Curto Hospital, Polla, Sant Arsenio, Italy
Eur J Gastroenterol Hepatol 19:535-42. 2007..The costs of capsule enteroscopy examination, however, make it uncertain whether the clinically relevant diagnostic gain is also associated with cost savings...
Progress in the prevention and control of viral hepatitis type B: closing remarksMario Rizzetto
Department of Gastroenterology, University of Torino, Torino, Italy
J Med Virol 67:463-6. 2002..Efforts to sustain immunization programs and to make vaccines and drugs available to countries with limited resources, are the main challenges to the eradication of hepatitis B in the next few decades...
Mesalamine-induced lung injury in a patient with ulcerative colitis and a confounding autoimmune background: a case reportGiovanni C Actis
Department of Gastroenterology, Ospedale Molinette, Corso Bramante 88, 10126 Torino, Italy
Mt Sinai J Med 72:136-40. 2005..The implications of the case are discussed...
Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinomaElisabetta Bugianesi
Department of Gastroenterology, Ospedale S Giovanni Battista, University of Turin, Turin, Italy
Gastroenterology 123:134-40. 2002..Nonalcoholic steatohepatitis (NASH) may progress to cirrhosis; whether NASH plays also a role in the development of hepatocellular carcinoma (HCC) is unknown...
Identification of HBV DNA sequences that are predictive of response to lamivudine therapyAlessia Ciancio
Georgetown University Medical Center, Division of Molecular Virology and Immunology, Rockville, MD, USA
Hepatology 39:64-73. 2004..Furthermore, at least in HBeAg-negative patients infected predominantly with HBV genotype D, specific viral DNA sequences which are present before therapy appear to be useful as predictors of long-term response to lamivudine treatment...
Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis BStephanos J Hadziyannis
Department of Medicine and Hepatology, Henry Dunant Hospital, Athens, Greece
N Engl J Med 352:2673-81. 2005..We evaluated the effect of continued therapy as compared with cessation of therapy...
Helicobacter pylori seroprevalence in patients with cirrhosis of the liver and hepatocellular carcinomaNicola Leone
Department of Gastro-Hepatology, Molinette Hospital, Via Chiabrera 34, 10126 Turin, Italy
Cancer Detect Prev 27:494-7. 2003..05); 11 out of 16 (68.7%) female patients were seropositive versus 9 out of 16 (56.2%) control subjects (P=n.s.). CONCLUSION: Seroprevalence of antibodies to H. pylori was found to be higher in patients with HCC than in controls...
Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis BStephanos J Hadziyannis
Department of Medicine and Hepatology, Henry Dunant Hospital, Athens, Greece
N Engl J Med 348:800-7. 2003..Adefovir dipivoxil, a nucleotide analogue, demonstrated clinically significant antiviral activity in patients with chronic hepatitis B in phase 1 and 2 clinical trials...
Thromboelastogram monitoring in the perioperative period of hepatectomy for adult living liver donationElisabetta Cerutti
Department of Anesthesiology and Intensive Care, University of Turin, Turin, Italy
Liver Transpl 10:289-94. 2004..TEG monitoring could be useful in the perioperative management of donors to guide antithrombotic treatment and increase the safety of the procedure...
Report of the monothematic EASL conference on liver transplantation for viral hepatitis (Paris, France, January 12-14, 2006)Didier Samuel
HepatoBiliary Centre, Inserm-Paris XI U 785, Paul Brousse Hospital, APHP, Villejuif, France
J Hepatol 45:127-43. 2006
A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patientsTing Tsung Chang
National Cheng Kung University Medical College, Tainan, Taiwan
Gastroenterology 129:1198-209. 2005..This randomized, dose-ranging, phase 2 study compared the efficacy and safety of entecavir with lamivudine in lamivudine-refractory patients...
Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 yearsStephanos J Hadziyannis
Department of Medicine and Hepatology, Henry Dunant Hospital, Athens, Greece
Gastroenterology 131:1743-51. 2006..We investigated the efficacy, safety, and resistance profile of adefovir dipivoxil treatment for up to 240 weeks...
Italian blood donors with anti-HBc and occult hepatitis B virus infectionPaola Manzini
Banca del Sangue e del Plasma, A O S Giovanni Battista di Torino, Corso Bramante 88, 10126 Torino, Italy
Haematologica 92:1664-70. 2007..The aim of our study was to evaluate the actual prevalence, viral load and genotype of occult HBV infections among first-time blood donors in north-western Italy and to suggest a way to minimize risks of transmission of this infection...
Definition of hepatitis B infection for the best practice in chronic disease and in immunosuppressed patientsAlfredo Marzano
J Hepatol 48:515-6; author reply 516. 2008
Extended lamivudine treatment in patients with HBeAg-negative chronic hepatitis BMario Rizzetto
Experimental Department of Gastroenterology, San Giovanni Battista Hospital C So Bramante, 88 10126 Turin, Italy
J Hepatol 42:173-9. 2005..The histological and clinical outcome of lamivudine 100mg/day was assessed in 76 HBeAg-negative chronic hepatitis B patients previously randomised to a double-blind comparison study of lamivudine and placebo...
Lamivudine-resistant chronic hepatitis B: an observational study on adefovir in monotherapy or in combination with lamivudineSilvia Gaia
Department of Gastroenterology and Hepatology, ASO San Giovanni Battista, c so Bramante 88, 10126 Turin, Italy
J Hepatol 48:540-7. 2008..In lamivudine-resistant patients with chronic hepatitis B (CHB), we compared efficacy, predictive response factors and changes in viral mutants in two antiviral approaches with adefovir...
Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudineVito Di Marco
Cattedra e U O C di Gastroenterologia, Clinica Medica, Universita di Palermo, Palermo, Italy
Hepatology 40:883-91. 2004..After 4 years of therapy, 39% of patients maintain a virological and biochemical response. Loss of virological response may lead to clinical deterioration in patients with cirrhosis...
Epidemiological and clinical burden of chronic hepatitis B virus/hepatitis C virus infection. A multicenter Italian studyGiovanni B Gaeta
Department of Medicine and Public Health, Unit of Infectious Diseases, Second University of Naples, Via Cotugno, 1 C O Osp Gesù e Maria, 80135 Naples, Italy
J Hepatol 39:1036-41. 2003..This study assess prevalence, risk factors, and clinical and virological features of dual hepatitis B virus (HBV)/hepatitis C virus (HCV) infection...
Response-guided therapy: optimizing treatment now and in the futurePatrick Marcellin
Antivir Ther 13:1-2. 2008
Inactive hepatitis B virus carriers: a favourable clinical conditionSilvia Gaia
Eur J Gastroenterol Hepatol 17:1435-6. 2005
Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin doseStephanos J Hadziyannis
Department of Medicine and Hepatology, Henry Dunant Hospital, Athens, Greece
Ann Intern Med 140:346-55. 2004..Treatment with pegylated interferon (peginterferon) and ribavirin for 48 weeks is more effective than conventional interferon and ribavirin in patients with chronic hepatitis C...
Ineffectiveness of hepatitis B vaccination in lamivudine-treated cirrhoticsElena Gentilcore
J Hepatol 40:357-8. 2004
Daily dose of interferon alpha-2b and ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection: a randomised controlled studyGianpiero Benetti
Section of Hepatology, Division of Medicine, Predabissi Hospital, Melegnano MI, Italy
Intern Emerg Med 1:113-8. 2006..The treatment of patients with hepatitis C virus (HCV) genotype 1 infection remains disappointing...
Potential role for the common cystic fibrosis DeltaF508 mutation in Crohn's diseaseFrancesca Bresso
Strategic Research Center IRIS, Karolinska Institutet, Stockholm, Sweden
Inflamm Bowel Dis 13:531-6. 2007..Given the important biological functions of CFTR in the intestine, we tested whether this mutation is of relevance to IBD...
Randomized trial of different screening strategies for colorectal cancer: patient response and detection ratesNereo Segnan
Centro Prevenzione Oncologica Regione Piemonte and Azienda Sanitaria Ospedaliera S Giovanni Battista, Torino, Italy
J Natl Cancer Inst 97:347-57. 2005..We compared the participation and detection rates achievable through different strategies of colorectal cancer screening...
Helicobacter pylori and coronary artery disease: which is the better target population?Rinaldo Pellicano
Dig Dis Sci 52:3041-2. 2007
Treatment of hepatitis C virus genotype 2 and 3 with pegylated interferon plus ribavirinMario Rizzetto
J Hepatol 42:275-6; author reply 276-7. 2005
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndromeGiulio Marchesini
Unit of Metabolic Diseases and Department of Internal Medicine, Alma Mater Studiorum University of Bologna, Bologna, Italy
Hepatology 37:917-23. 2003..The increasing prevalence of obesity, coupled with diabetes, dyslipidemia, hypertension, and ultimately the metabolic syndrome puts a very large population at risk of forthcoming liver failure in the next decades...
Helicobacter species sequences in liver samples from patients with and without hepatocellular carcinomaRinaldo Pellicano
Ambulatorio di Gastroenterologia, Ospedale S Giovanni Battista, Via Chiabrera 34, III piano, 10126 Torino, Italy
World J Gastroenterol 10:598-601. 2004..CONCLUSION: Helicobacter spp., carcinogenic in mice, were found at a higher frequency in the liver of patients with HCV-related cirrhosis and HCC than those in patients without primary liver disease...
