Patrizia Rise

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Different patterns characterize Omega 6 and Omega 3 long chain polyunsaturated fatty acid levels in blood from Italian infants, children, adults and elderly
    P Rise
    DiSFeB, Department of Pharmacological and Biomolecular Sciences, University of Milan, Via Balzaretti 9, Milan, Italy Electronic address
    Prostaglandins Leukot Essent Fatty Acids 89:215-20. 2013
  2. ncbi request reprint Fatty acid composition of plasma, blood cells and whole blood: relevance for the assessment of the fatty acid status in humans
    P Rise
    Department of Pharmacological Sciences, E Grossi Paoletti Center, University of Milan, Milan, Italy
    Prostaglandins Leukot Essent Fatty Acids 76:363-9. 2007
  3. ncbi request reprint Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Eur J Pharmacol 571:97-105. 2007
  4. doi request reprint Whole blood fatty acid analysis with micromethod in cystic fibrosis and pulmonary disease
    Patrizia Rise
    Universita degli Studi di Milano, Dipartimento di Scienze Farmacologiche, Via Balzaretti 9, 20133 Milano, Italy
    J Cyst Fibros 9:228-33. 2010
  5. ncbi request reprint Application of a direct transmethylation method to the analysis of fatty acid profile in circulating and cultured cells
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, Italy
    Anal Biochem 346:182-4. 2005
  6. ncbi request reprint Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Biochem Pharmacol 69:1095-100. 2005
  7. ncbi request reprint Synthesis of long-chain polyunsaturated fatty acids is inhibited in vivo in hypercholesterolemic rabbits and in vitro by oxysterols
    P Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Prostaglandins Leukot Essent Fatty Acids 71:79-86. 2004
  8. ncbi request reprint Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP-1 cells
    P Rise
    Department of Pharmacological Sciences, University of Milan, 20133 Milano, Italy
    Lipids 38:841-6. 2003
  9. ncbi request reprint Relative potencies of statins in reducing cholesterol synthesis and enhancing linoleic acid metabolism
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Eur J Pharmacol 467:73-5. 2003
  10. doi request reprint The in vitro effects of cigarette smoke on fatty acid metabolism are partially counteracted by simvastatin
    P Rise
    Department of Pharmacological Sciences, University of Milano via Balzaretti 9, 20133 Milano, Italy
    Prostaglandins Leukot Essent Fatty Acids 80:71-5. 2009

Detail Information

Publications19

  1. ncbi request reprint Different patterns characterize Omega 6 and Omega 3 long chain polyunsaturated fatty acid levels in blood from Italian infants, children, adults and elderly
    P Rise
    DiSFeB, Department of Pharmacological and Biomolecular Sciences, University of Milan, Via Balzaretti 9, Milan, Italy Electronic address
    Prostaglandins Leukot Essent Fatty Acids 89:215-20. 2013
    ..In contrast, the lowest levels of Omega 3 PUFA, especially of DHA, are found in children, probably reflecting inadequate dietary intakes, with possible consequences on the health status at subsequent ages. ..
  2. ncbi request reprint Fatty acid composition of plasma, blood cells and whole blood: relevance for the assessment of the fatty acid status in humans
    P Rise
    Department of Pharmacological Sciences, E Grossi Paoletti Center, University of Milan, Milan, Italy
    Prostaglandins Leukot Essent Fatty Acids 76:363-9. 2007
    ..Phospholipids of plasma and red blood cell are the major contributors to the FA amount and profile in WB. In conclusion, the FA profile of WB reflects the FA status and WB could be an adequate specimen for the assessment of FA intakes...
  3. ncbi request reprint Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Eur J Pharmacol 571:97-105. 2007
    ..These results taken together suggest that SREBP-1 is involved in the early regulation of delta5 desaturase gene by simvastatin, in THP-1 cells...
  4. doi request reprint Whole blood fatty acid analysis with micromethod in cystic fibrosis and pulmonary disease
    Patrizia Rise
    Universita degli Studi di Milano, Dipartimento di Scienze Farmacologiche, Via Balzaretti 9, 20133 Milano, Italy
    J Cyst Fibros 9:228-33. 2010
    ..To assess fatty acid (FA) profiles in whole blood of 90 cystic fibrosis patients (CF) and 30 control subjects (C) and to correlate FA changes to the severity of respiratory disease...
  5. ncbi request reprint Application of a direct transmethylation method to the analysis of fatty acid profile in circulating and cultured cells
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, Italy
    Anal Biochem 346:182-4. 2005
  6. ncbi request reprint Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Biochem Pharmacol 69:1095-100. 2005
    ..The greater n-3 FA metabolism in THP-1 cells may have favourable functional effects...
  7. ncbi request reprint Synthesis of long-chain polyunsaturated fatty acids is inhibited in vivo in hypercholesterolemic rabbits and in vitro by oxysterols
    P Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Prostaglandins Leukot Essent Fatty Acids 71:79-86. 2004
    ..In conclusion, atherogenic oxysterols interfere with the production of long-chain polyunsaturated fatty acids from their precursors both in hypercholesterolemic rabbits and in cultured cells...
  8. ncbi request reprint Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP-1 cells
    P Rise
    Department of Pharmacological Sciences, University of Milan, 20133 Milano, Italy
    Lipids 38:841-6. 2003
    ..In fact, simvastatin decreased cholesterol synthesis and enhanced LA conversion (mainly delta5 desaturation), whereas curcumin and nicardipin decreased delta5 desaturation, with a limited effect on cholesterol synthesis...
  9. ncbi request reprint Relative potencies of statins in reducing cholesterol synthesis and enhancing linoleic acid metabolism
    Patrizia Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Eur J Pharmacol 467:73-5. 2003
    ....
  10. doi request reprint The in vitro effects of cigarette smoke on fatty acid metabolism are partially counteracted by simvastatin
    P Rise
    Department of Pharmacological Sciences, University of Milano via Balzaretti 9, 20133 Milano, Italy
    Prostaglandins Leukot Essent Fatty Acids 80:71-5. 2009
    ..On the contrary, cigarette smoke (CS) negatively and dose-dependently affects the LC-PUFA production...
  11. ncbi request reprint Effects of cigarette smoke on cell viability, linoleic acid metabolism and cholesterol synthesis, in THP-1 cells
    Silvia Ghezzi
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Lipids 42:629-36. 2007
    ..In conclusion, CS affects lipid metabolism, inhibiting LA conversion and desaturase activities. CS also shifts the "de novo" lipid synthesis from free cholesterol to TG and CE, where LA is preferentially esterified...
  12. doi request reprint Whole blood fatty acid composition at birth: from the maternal compartment to the infant
    Carlo Agostoni
    Department of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Clin Nutr 30:503-5. 2011
    ..We here describe the application of a simplified microanalytical procedure to compare the FA profile of maternal, umbilical cord and infant whole blood, inclusive of all circulating lipid fractions and cells...
  13. doi request reprint Whole blood fatty acid composition differs in term versus mildly preterm infants: small versus matched appropriate for gestational age
    Carlo Agostoni
    Department of Pediatrics, University of Milan, Milan, Italy
    Pediatr Res 64:298-302. 2008
    ..001). Term SGA had significantly lower levels of total monounsaturated FA and higher levels of eicosapentaenoic acid. Therefore, the 4-d whole blood FA pattern is associated with both GA and birth weight...
  14. doi request reprint Membrane composition and cellular responses to fatty acid intakes and factors explaining the variation in response
    Carlo Agostoni
    Pediatric Clinic 2, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, Milan, Italy
    Nestle Nutr Inst Workshop Ser 77:111-20. 2013
    ..Accordingly, different amounts of dietary PUFA may be necessary to meet the requirements for these nutrients in development and disease prevention on an individual basis...
  15. ncbi request reprint Omega-3 fatty acid ethyl esters increase heart rate variability in patients with coronary disease
    Barbara Villa
    Department of Pharmacological Sciences, Centre E Grossi Paoletti, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Pharmacol Res 45:475. 2002
    ....
  16. ncbi request reprint Lipid transport, dietary fats, and endogenous lipid synthesis: hypotheses on saturation and competition processes
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Nutr Health 18:127-32. 2006
    ..In turn, a theory on the dietary vs endogenous contribution to circulating fatty acids, including those known as non-essential, is discussed based on critical interpretation of original data...
  17. pmc Bioequivalence of two omega-3 fatty acid ethyl ester formulations: a case of clinical pharmacology of dietary supplements
    Claudio Galli
    Department of Pharmacological Sciences, Universita di Milano, Milan, Italy
    Br J Clin Pharmacol 74:60-5. 2012
    ..If repeated doses are given, this may lead to errors because of variable dietary fish intake. If a single dose is selected, this needs to be large, since omega-3 LC-PUFA are present in many compartments...
  18. ncbi request reprint Fish consumption, omega 3 fatty acids and cardiovascular disease. The science and the clinical trials
    Claudio Galli
    Laboratory of Lipid Nutrition and Pharmacology, Department of Pharmacological Sciences, University of Milano, Via Balzaretti 9, 20133 Milano, Italy
    Nutr Health 20:11-20. 2009
    ..e. the assessment of the omega 3 fatty acid status, correlations between levels and cardiovascular indexes and bioavailability of different forms of administration), these recommendations are highly valuable...
  19. ncbi request reprint Dietary intake of fish vs. formulations leads to higher plasma concentrations of n-3 fatty acids
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, 20133 Milan, Italy
    Lipids 38:415-8. 2003
    ....