Luisella Righi

Summary

Affiliation: University of Turin
Country: Italy

Publications

  1. ncbi request reprint Prognostic role of bone sialoprotein in clear cell renal carcinoma
    Luisella Righi
    Department of Medical Sciencesand Integrated Diagnostic, University of Genoa, San Martino Hospital, Genoa, Italy
    Anticancer Res 33:2679-87. 2013
  2. pmc Detection and characterization of classical and "uncommon" exon 19 Epidermal Growth Factor Receptor mutations in lung cancer by pyrosequencing
    Luisella Righi
    Divisions of Pathology, University of Torino, Regione Gonzole 10, Torino, Orbassano 10043, Italy
    BMC Cancer 13:114. 2013
  3. doi request reprint Human achaete-scute homolog-1 expression in neuroendocrine breast carcinoma
    Luisella Righi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Virchows Arch 460:415-21. 2012
  4. doi request reprint Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung
    Luisella Righi
    Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Regione Gonzole 10, Orbassano, Turin, Italy
    Endocr Relat Cancer 17:977-87. 2010
  5. doi request reprint Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases
    L Righi
    Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Torino
    Ann Oncol 21:548-55. 2010
  6. doi request reprint Caveolin-1 expression in lung carcinoma varies according to tumour histotype and is acquired de novo in brain metastases
    Paola Cassoni
    Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
    Histopathology 55:20-7. 2009
  7. doi request reprint Expression and pharmacological inhibition of thymidylate synthase and Src kinase in nonsmall cell lung cancer
    Paolo Ceppi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Italy
    Int J Cancer 130:1777-86. 2012
  8. doi request reprint Thymidylate synthase expression in gastroenteropancreatic and pulmonary neuroendocrine tumors
    Paolo Ceppi
    Thoracic Oncology Unit, Pathology Division, Department of Clinical and Biological Sciences, University of Torino, San Luigi Hospital, Torino, Italy
    Clin Cancer Res 14:1059-64. 2008
  9. doi request reprint Desmocollin-3: a new marker of squamous differentiation in undifferentiated large-cell carcinoma of the lung
    Valentina Monica
    Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Torino, Italy
    Mod Pathol 22:709-17. 2009
  10. doi request reprint Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy
    Luisella Righi
    University of Torino, Division of Pathology, Thoracic Oncology, and Thoracic Surgery, Department of Clinical and Biological Sciences at San Luigi Hospital, Orbassano, Italy
    J Clin Oncol 28:1534-9. 2010

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Prognostic role of bone sialoprotein in clear cell renal carcinoma
    Luisella Righi
    Department of Medical Sciencesand Integrated Diagnostic, University of Genoa, San Martino Hospital, Genoa, Italy
    Anticancer Res 33:2679-87. 2013
    ..We aimed to define the predictive (of bone spread) and prognostic role of BSP and OPN immunohistochemical expression in clear cell RCC...
  2. pmc Detection and characterization of classical and "uncommon" exon 19 Epidermal Growth Factor Receptor mutations in lung cancer by pyrosequencing
    Luisella Righi
    Divisions of Pathology, University of Torino, Regione Gonzole 10, Torino, Orbassano 10043, Italy
    BMC Cancer 13:114. 2013
    ....
  3. doi request reprint Human achaete-scute homolog-1 expression in neuroendocrine breast carcinoma
    Luisella Righi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Virchows Arch 460:415-21. 2012
    ..0062). hASH-1 expression occurs in breast cancers with NE differentiation regardless of the extent of the NE cell population, and it is restricted to a subset of tumor cells having a low proliferative potential...
  4. doi request reprint Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung
    Luisella Righi
    Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Regione Gonzole 10, Orbassano, Turin, Italy
    Endocr Relat Cancer 17:977-87. 2010
    ....
  5. doi request reprint Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases
    L Righi
    Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Torino
    Ann Oncol 21:548-55. 2010
    ....
  6. doi request reprint Caveolin-1 expression in lung carcinoma varies according to tumour histotype and is acquired de novo in brain metastases
    Paola Cassoni
    Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
    Histopathology 55:20-7. 2009
    ..To study caveolin-1 (Cav-1) expression in metastatic lung carcinomas...
  7. doi request reprint Expression and pharmacological inhibition of thymidylate synthase and Src kinase in nonsmall cell lung cancer
    Paolo Ceppi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Italy
    Int J Cancer 130:1777-86. 2012
    ..The data of our study suggest that TS and Src may belong to a common pathway that bears prognostic significance in NSCLC, and that Src represents a potential target to improve the efficacy of TS-inhibiting agents...
  8. doi request reprint Thymidylate synthase expression in gastroenteropancreatic and pulmonary neuroendocrine tumors
    Paolo Ceppi
    Thoracic Oncology Unit, Pathology Division, Department of Clinical and Biological Sciences, University of Torino, San Luigi Hospital, Torino, Italy
    Clin Cancer Res 14:1059-64. 2008
    ..Neuroendocrine tumors (NET) represent potential targets of antifolate agents, but no data on TS expression level in these tumors are currently available...
  9. doi request reprint Desmocollin-3: a new marker of squamous differentiation in undifferentiated large-cell carcinoma of the lung
    Valentina Monica
    Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Torino, Italy
    Mod Pathol 22:709-17. 2009
    ....
  10. doi request reprint Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy
    Luisella Righi
    University of Torino, Division of Pathology, Thoracic Oncology, and Thoracic Surgery, Department of Clinical and Biological Sciences at San Luigi Hospital, Orbassano, Italy
    J Clin Oncol 28:1534-9. 2010
    ..The relationship between thymidylate synthase (TS) expression and outcome in patients with malignant pleural mesothelioma (MPM) treated with pemetrexed (P) was retrospectively evaluated...
  11. doi request reprint Epidermal growth factor receptor gene in primary tumor and metastatic sites from non-small cell lung cancer
    Lorenzo Daniele
    Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy
    J Thorac Oncol 4:684-8. 2009
    ..Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors are capable of reducing brain and adrenal metastases. However, the EGFR status may be discordant between primary NSCLC and the corresponding metastases...
  12. ncbi request reprint Changes in prostate cancer at radical prostatectomy during the prostate specific antigen era: an Italian experience
    Enrico Bollito
    Department of Pathology, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Italy
    Anal Quant Cytol Histol 30:152-9. 2008
    ..To assess changes in prostate cancer clinical and pathologic features by review of 15 years' experience with radical prostatectomy...
  13. ncbi request reprint Neuroendocrine differentiation in breast cancer: established facts and unresolved problems
    Luisella Righi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Torino, Italy
    Semin Diagn Pathol 27:69-76. 2010
    ..The clinical effect of neuroendocrine breast cancer is still a matter of debate; however, when compared with unselected breast cancers, NEBCs show a less aggressive clinical behavior...
  14. doi request reprint Prognostic role of osteopontin expression in malignant pleural mesothelioma
    Susanna Cappia
    Department of Clinical and Biological Sciences, University of Torino at St Luigi Hospital, Torino, Italy
    Am J Clin Pathol 130:58-64. 2008
    ..0001), and overall survival analysis showed that low osteopontin expression was associated with longer survival; multivariate analysis confirmed the value of osteopontin expression as an independent prognostic factor (P< .0001)...
  15. ncbi request reprint Neuro-endocrine tumours of the lung. A review of relevant pathological and molecular data
    Luisella Righi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Virchows Arch 451:S51-9. 2007
    ..The "molecular classification" of NE tumours should be integrated to morphology, for a better definition of the different histological types and a more appropriate selection of the therapeutic strategy...
  16. ncbi request reprint Basaloid adenocarcinoma. A new variant of pulmonary adenocarcinoma
    Valerio Marci
    Department of Pathology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Virchows Arch 451:729-36. 2007
    ..These findings indicate that a basaloid variant of adenocarcinoma is also existing in the spectrum of basaloid carcinomas of the lung...
  17. doi request reprint The pathological diagnosis of neuroendocrine tumors: common questions and tentative answers
    Marco Volante
    Divisions of Pathology, University of Turin at San Luigi Hospital, Orbassano, Torino, Italy
    Virchows Arch 458:393-402. 2011
    ..The present paper is an overview of the most frequently asked questions and an attempt to provide practical answers related to NEN diagnosis in the daily pathology work...
  18. pmc Estrogen receptor alpha is a novel marker expressed by follicular dendritic cells in lymph nodes and tumor-associated lymphoid infiltrates
    Anna Sapino
    Department of Biomedical Science and Human Oncology, University of Turin Medical School, Turin, Italy
    Am J Pathol 163:1313-20. 2003
    ..Taken together, these results open new perspectives on the effects of sex steroids and their antagonists on the human response in cancer and inflammation...
  19. ncbi request reprint Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms
    Marco Volante
    Department of Clinical and Biological Sciences, University of Turin and San Luigi Hospital, Regione Gonzole10, 10043, Orbassano, Torino, Italy
    Virchows Arch 451:S61-9. 2007
    ..Moreover, molecular and clinical aspects, which might help to understand their possible histogenesis and biological behavior, will be reviewed...
  20. ncbi request reprint Somatostatin receptor type 2A immunohistochemistry in neuroendocrine tumors: a proposal of scoring system correlated with somatostatin receptor scintigraphy
    Marco Volante
    Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Orbassano, Turin, Italy
    Mod Pathol 20:1172-82. 2007
    ....
  21. doi request reprint Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: a retrospective study of 103 cases with surgical correlation
    Luisella Righi
    Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Cancer 117:3416-23. 2011
    ..Immunohistochemistry highlights cell differentiation lineages and, in this study, it was applied to maximize the proportion of accurately subtyped NSCLC not otherwise specified (NOS) on fine-needle aspiration cytology (FNAC) samples...
  22. ncbi request reprint Expression of apocrine differentiation markers in neuroendocrine breast carcinomas of aged women
    A Sapino
    Department of Biomedical Sciences and Human Oncology, University of Turin, Via Santena 7, 10126 Turin, Italy
    Mod Pathol 14:768-76. 2001
    ..In addition, the possibility for using Chs or GCDFP-15 serum values in the follow-up of these patients, as demonstrated in two cases of the present series, can justify the immunophenotyping of the tumors...
  23. ncbi request reprint Clinical significance of neuroendocrine carcinoma of the breast
    A Sapino
    Department of Biomedical Sciences and Human Oncology, University of Turin, Italy
    Ann Oncol 12:S115-7. 2001
    ..In the present work, the clinical significance of pure' NE differentiation in breast carcinoma and of its 'variants' will be analyzed...
  24. ncbi request reprint Expression of CD31 by cells of extensive ductal in situ and invasive carcinomas of the breast
    A Sapino
    Department of Biomedical Sciences and Human Oncology, University of Torino Medical School, Torino, Italy
    J Pathol 194:254-61. 2001
    ..CD31 expression mainly correlates with tumour cells spreading within the ductal system. Finally, the invasive phenotype requires the co-expression of CD31 and CD44...
  25. pmc A modified Trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer
    G Bussolati
    Department of Biomedical Sciences and Human Oncology, University of Turin, Torino, Italy
    Br J Cancer 92:1261-7. 2005
    ..Biotinylated Trastuzumab can thus be used for immunohistochemical detection of HER-2 overexpression in breast cancer, and has the potential to identify patients likely to benefit from Trastuzumab treatment...
  26. doi request reprint Role of surgical resection in colorectal lung metastases: analysis of 137 patients
    Piero Borasio
    Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Turin, Italy
    Int J Colorectal Dis 26:183-90. 2011
    ..The aim of this study is to investigate clinicopathologic characteristics and to identify prognostic factors in patients undergoing pulmonary metastasectomy for colorectal carcinoma...
  27. ncbi request reprint 34betaE12 cytokeratin immunodetection in the differential diagnosis of neuroendocrine carcinomas of the breast
    M Papotti
    Department of Biomedical Sciences and Oncology, University of Turin, Torino, Italy
    Appl Immunohistochem Mol Morphol 9:229-33. 2001
    ..HMW CK can be added to the list of markers useful in the differential diagnosis of NE from non-NE tumors...
  28. pmc Role of CD31/platelet endothelial cell adhesion molecule-1 expression in in vitro and in vivo growth and differentiation of human breast cancer cells
    Luisella Righi
    Department of Genetics, Biology, and Biochemistry, Laboratory of Immunogenetics, University of Torino Medical School, Torino, Italy
    Am J Pathol 162:1163-74. 2003
    ..In conclusion, CD31 expression reverts the undifferentiated morphology and aggressive behavior of MDA-MB-231 cells, indicating its active role in the morphogenesis of breast ductal in situ carcinomas...