M Reale

Summary

Affiliation: University of Chieti
Country: Italy

Publications

  1. ncbi Relation between Pro-inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients
    Marcella Reale
    Department of Experimental and Clinical Sciences, University G D Annunzio Chieti Pescara, Via dei Vestini, 31 66100 Chieti, Italy
    Int J Mol Sci 13:12656-64. 2012
  2. ncbi Mitochondria as an easy target to oxidative stress events in Parkinson's disease
    Marcella Reale
    Department of Biomedical Sciences, University G d Annunzio of Chieti Pescara, Italy
    CNS Neurol Disord Drug Targets 11:430-8. 2012
  3. ncbi Relationship between inflammatory mediators, Aβ levels and ApoE genotype in Alzheimer disease
    M Reale
    Dept of Oncology and Experimental Medicine, Unit of Immunodiagnostic, University G D Annunzio, Chieti, Italy
    Curr Alzheimer Res 9:447-57. 2012
  4. ncbi Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls
    Marcella Reale
    Department of Oncology and Experimental Medicine, University G, D Annunzio, Via dei Vestini, 31, Chieti, 66123, Italy
    BMC Neurosci 12:13. 2011
  5. ncbi Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases
    M Reale
    University G D Annunzio, Chieti Pescara, Dept Oncology and Neuroscience, Chieti, Italy
    Mini Rev Med Chem 9:1229-41. 2009
  6. ncbi Peripheral cytokines profile in Parkinson's disease
    M Reale
    Department of Oncology and Neuroscience, University G D Annunzio Chieti Pescara, Italy
    Brain Behav Immun 23:55-63. 2009
  7. ncbi Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease
    Marcella Reale
    Department of Oncology and Neuroscience, University G D Annunzio, Chieti, Italy
    J Alzheimers Dis 14:147-59. 2008
  8. ncbi Modulation of MCP-1 and iNOS by 50-Hz sinusoidal electromagnetic field
    Marcella Reale
    Department of Oncology and Neuroscience, Universita degli Studi G D Annunzio, Chieti, Italy
    Nitric Oxide 15:50-7. 2006
  9. ncbi Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients
    Marcella Reale
    Department of Oncology and Neuroscience, Unit of Immunology, University G D Annunzio, Via dei Vestini, 31, 66123 Chieti, Italy
    Exp Gerontol 40:165-71. 2005
  10. ncbi The acetylcholinesterase inhibitor, Donepezil, regulates a Th2 bias in Alzheimer's disease patients
    Marcella Reale
    Department of Oncology and Neuroscience, Unit of Immunology, University G D Annunzio, Via dei Vestini 31, 66123 Chieti, Italy
    Neuropharmacology 50:606-13. 2006

Collaborators

Detail Information

Publications54

  1. ncbi Relation between Pro-inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients
    Marcella Reale
    Department of Experimental and Clinical Sciences, University G D Annunzio Chieti Pescara, Via dei Vestini, 31 66100 Chieti, Italy
    Int J Mol Sci 13:12656-64. 2012
    ....
  2. ncbi Mitochondria as an easy target to oxidative stress events in Parkinson's disease
    Marcella Reale
    Department of Biomedical Sciences, University G d Annunzio of Chieti Pescara, Italy
    CNS Neurol Disord Drug Targets 11:430-8. 2012
    ..ROS can affect mitochondrial DNA (mtDNA) causing modulation in synthesis of electron transport chain (ETC) components, decreased ATP production, and increased leakage of ROS...
  3. ncbi Relationship between inflammatory mediators, Aβ levels and ApoE genotype in Alzheimer disease
    M Reale
    Dept of Oncology and Experimental Medicine, Unit of Immunodiagnostic, University G D Annunzio, Chieti, Italy
    Curr Alzheimer Res 9:447-57. 2012
    ....
  4. ncbi Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls
    Marcella Reale
    Department of Oncology and Experimental Medicine, University G, D Annunzio, Via dei Vestini, 31, Chieti, 66123, Italy
    BMC Neurosci 12:13. 2011
    ..We enrolled 51 untreated first-episode schizophrenics (SC) and 40 healthy subjects (HC) and the levels of MCP-1, MIP-1α, IL-8, IL-18, IFN-γ and RANTES were determined by Elisa method in cell-free supernatants of PBMC cultures...
  5. ncbi Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases
    M Reale
    University G D Annunzio, Chieti Pescara, Dept Oncology and Neuroscience, Chieti, Italy
    Mini Rev Med Chem 9:1229-41. 2009
    ..The data reviewed in this paper suggest that, in neurodegenerative disease, cytokines are links between peripheral immune system and nervous system dysfunction...
  6. ncbi Peripheral cytokines profile in Parkinson's disease
    M Reale
    Department of Oncology and Neuroscience, University G D Annunzio Chieti Pescara, Italy
    Brain Behav Immun 23:55-63. 2009
    ..The overall results strengthen and extend the knowledge of the peripheral dysregulation in the cytokine network associated with PD...
  7. ncbi Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease
    Marcella Reale
    Department of Oncology and Neuroscience, University G D Annunzio, Chieti, Italy
    J Alzheimers Dis 14:147-59. 2008
    ..The observed patterns of cyto-chemokine involvement strengthen the questions regarding the inflammatory theory in AD, and raise a pathophysiologic role for selective alteration of cyto-chemokine network...
  8. ncbi Modulation of MCP-1 and iNOS by 50-Hz sinusoidal electromagnetic field
    Marcella Reale
    Department of Oncology and Neuroscience, Universita degli Studi G D Annunzio, Chieti, Italy
    Nitric Oxide 15:50-7. 2006
    ..However, additional studies are necessary to demonstrate that EMF acts as a nonpharmacological inhibitor of NO and inducer of MCP-1 in some diseases where the balance of MCP-1 and NO may be important...
  9. ncbi Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients
    Marcella Reale
    Department of Oncology and Neuroscience, Unit of Immunology, University G D Annunzio, Via dei Vestini, 31, 66123 Chieti, Italy
    Exp Gerontol 40:165-71. 2005
    ..In conclusion, the results of this study show that the complex pathology in AD may be reflected in a pattern of altered cytokine secretion from PBMC...
  10. ncbi The acetylcholinesterase inhibitor, Donepezil, regulates a Th2 bias in Alzheimer's disease patients
    Marcella Reale
    Department of Oncology and Neuroscience, Unit of Immunology, University G D Annunzio, Via dei Vestini 31, 66123 Chieti, Italy
    Neuropharmacology 50:606-13. 2006
    ..The different amounts of MCP-1 and IL-4 observed might reflect the different states of activation and/or responsiveness of PBMC, that in AD patients could be kept in an activated state by pro-inflammatory cytokines...
  11. ncbi Expression of lymphocyte subpopulations, cytokine serum levels, and blood and urinary trace elements in asymptomatic atopic men exposed to an urban environment
    P Boscolo
    Department of Medicine and Sciences of Aging, Center of Occupational Medicine and Ergophthalmology, University G D Annunzio, Chieti, Italy
    Int Arch Occup Environ Health 72:26-32. 1999
    ..This suggests that Pb may enhance the incidence of atopy in populations exposed to an urban environment...
  12. ncbi Lymphocyte subpopulations, cytokines and trace elements in asymptomatic atopic women exposed to an urban environment
    P Boscolo
    Department of Medicine and Sciences of Aging, University G D Annunzio, Chieti, Italy
    Life Sci 67:1119-26. 2000
    ..On the whole, this study demonstrates that exposure to low levels of toxic agents, produced by vehicular traffic in an urban environment, exerts effects on immune functions of women...
  13. ncbi Extremely low frequency electromagnetic fields modulate expression of inducible nitric oxide synthase, endothelial nitric oxide synthase and cyclooxygenase-2 in the human keratinocyte cell line HaCat: potential therapeutic effects in wound healing
    A Patruno
    Department of Drug Sciences, University G d Annunzio of Chieti Pescara, Via dei Vestini, 66100 Chieti, Italy
    Br J Dermatol 162:258-66. 2010
    ....
  14. ncbi Effects of low frequency electromagnetic fields on expression of lymphocyte subsets and production of cytokines of men and women employed in a museum
    P Boscolo
    Department of Medicine and Sciences of Ageing, University G D Annunzio, Chieti, Italy
    Sci Total Environ 270:13-20. 2001
    ..This may suggest that ELMFs reduces blood NK lymphocytes by combined effects on the immune and nervous systems...
  15. ncbi "In vitro" effects of different arsenic compounds on PBMC (preliminary study)
    L Di Giampaolo
    Section of Occupational Medicine, Allergology and Clinical Immunology, Department of Medicine and Science of Ageing, G. D'Annunzio University of Chieti and Pescara, Via dei Vestini 66100, Chieti, Italy
    G Ital Med Lav Ergon 26:183-6. 2004
    ..This study shows that the immune effects of As salts depends on speciation; moreover, the immunotoxicity of inorganic arsenic in part depends on the intracellular bio-synthesis of MMAs(III) from MMAs(V)...
  16. ncbi Kinetic study on the effects of extremely low frequency electromagnetic field on catalase, cytochrome P450 and inducible nitric oxide synthase in human HaCaT and THP-1 cell lines
    A Patruno
    UniversityG d Annunzio di Chieti Pescara, Dip Oncology and Experimental Medicine, Unit Immunodiagnostica, Nuovo Polo Didattico, Ed C, III Livello, Chieti, Italy
    CNS Neurol Disord Drug Targets 10:936-44. 2011
    ..These new insights may be important for ELF-EMF application particularly for wound healing, tissue regeneration, Parkinson's and Alzheimer's diseases...
  17. ncbi Extremely low frequency electromagnetic field enhances human keratinocyte cell growth and decreases proinflammatory chemokine production
    G Vianale
    Department of Oncology and Neurosciences, University G d Annunzio of Chieti Pescara, 66013 Chieti, Italy
    Br J Dermatol 158:1189-96. 2008
    ..Several studies have shown that an electromagnetic field (EMF) can influence both inflammatory processes and repair mechanisms including wound healing on different tissue models...
  18. ncbi Reduction of free radicals in multiple sclerosis: effect of glatiramer acetate (Copaxone)
    C Iarlori
    Department of Oncology and Neuroscience, University G D Annunzio, Chieti, Italy
    Mult Scler 14:739-48. 2008
    ..The inhibition of the production of free radicals in PBAMs may represent a new therapeutic mechanism against inflammation during MS...
  19. ncbi Differential expression and secretion of RANTES and MCP-1 in activated peripheral blood mononuclear cell cultures of atopic subjects
    M Reale
    Department of Oncology and Neurosciences, Immunology Division, School of Medicine, University of Chieti, Via dei Vestini, 66013, Chieti, Italy
    Immunol Lett 76:7-14. 2001
    ..These studies emphasize the importance of chemokine selectivity during inflammation...
  20. ncbi Effects of electromagnetic fields produced by radiotelevision broadcasting stations on the immune system of women
    P Boscol
    Department of Medicine and Science of Ageing, University G D Annunzio, Chieti, Italy
    Sci Total Environ 273:1-10. 2001
    ..In conclusion, this study demonstrates that high frequency ELMFs reduce cytotoxic activity in the peripheral blood of women without a dose-response effect...
  21. ncbi Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines
    Marcella Reale
    Immunology Unit, Department of Oncology and Neuroscience, University UD'A, Via dei Vestini, 66013 Chieti, Italy
    J Neuroimmunol 148:162-71. 2004
    ....
  22. ncbi Expression and production of two selected beta-chemokines in peripheral blood mononuclear cells from patients with Alzheimer's disease
    Carla Iarlori
    Department of Oncology and Neuroscience, Chieti, Italy
    Exp Gerontol 40:605-11. 2005
    ....
  23. ncbi Iloprost treatment summer-suspension: effects on skin thermal properties and cytokine profile in systemic sclerosis patients
    M Auriemma
    Department of Experimental and Clinical Sciences University G D Annunzio Chieti Pescara, Chieti, Italy
    G Ital Dermatol Venereol 148:209-16. 2013
    ..Iloprost showed to modulate only IL-23 expression corroborating the idea that this cytokine is crucial for SSc development and progression...
  24. ncbi Expression and secretion of RANTES by human peripheral blood CD4+ cells are dependent on the presence of monocytes
    P Conti
    Department of Oncology and Neurosciences, University of Chieti School of Medicine, Italy
    Ann Clin Lab Sci 31:75-84. 2001
    ..These data show that CD4+ cells need monocytes to express and secrete appreciable amounts of RANTES...
  25. ncbi Integrated software suite for magnetocardiographic data analysis--a proposal based on an interactive programming environment
    S Comani
    Department of Clinical Sciences and Bio imaging, Section of Physical Sceinces, Chieti University, Italy
    Methods Inf Med 44:114-23. 2005
    ....
  26. ncbi Involvement of phosphatidylserine exposure in the recognition and phagocytosis of uremic erythrocytes
    M Bonomini
    Department of Medicine, Institute of Nephrology, SS Annunziata Hospital, Via dei Vestini, 66013 Chieti Scalo, Italy
    Am J Kidney Dis 37:807-14. 2001
    ..These findings suggest that a PS-recognition mechanism may promote the susceptibility of uremic RBCs to phagocytosis and thus be involved in the shortened erythrocyte life span of uremia...
  27. ncbi [In vitro study on the immune effects of the exposure to palladium nanoparticles]
    P Boscolo
    Medicina del Lavoro dell Università G D Annunzio di Chieti Pescara, Italy
    G Ital Med Lav Ergon 32:332-5. 2010
    ..In conclusion, Pd salt inhibits the cytokine release from PBMC, whereas Pd nanoparticles exert modulatory effects enhancing release of IFN-gamma which plays an important role in autoimmune diseases...
  28. ncbi Work stress and innate immune response
    P Boscolo
    Unit of Occupational Medicine, University of Chieti, Italy
    Int J Immunopathol Pharmacol 24:51S-54S. 2011
    ..Monitoring blood NK response may thus be included in the health programs as an indirect index of stressful job and/or poor lifestyle...
  29. ncbi Effect of electromagnetic fields on several CD markers and transcription and expression of CD4
    P Conti
    Department of Oncology and Neurosciences, University of Chieti, Medical School, Italy
    Immunobiology 201:36-48. 1999
    ..The findings from this study demonstrate that under our defined experimental conditions there is evidence that ELF-EMF has a slight effect on CD4, CD14 and CD16 receptor expression, while the other CD receptors are not affected...
  30. ncbi Serum levels of soluble adhesion molecules in chronic renal failure and dialysis patients
    M Bonomini
    Institute of Nephrology, Department of Medicine and Aging, University of Chieti, Italy
    Nephron 79:399-407. 1998
    ..The elevated serum levels of these proteins probably reflect inadequate clearance as well as enhanced synthesis/release...
  31. ncbi Antiinflammatory effects in THP-1 cells treated with verbascoside
    Lorenza Speranza
    Department of Biomorphology, University G D Annunzio, Chieti, Italy
    Phytother Res 24:1398-404. 2010
    ..Based on these results it is hypothesized that verbascoside has antiinflammatory properties since it reduces the production of superoxide radicals and consequently reduces the activity of iNOS...
  32. ncbi Blood natural killer activity is reduced in men with occupational stress and job insecurity working in a university
    Paolo Boscolo
    Unit of Occupational Medicine, University G d Annunzio of Chieti Pescara, Chieti, Italy
    Int Arch Occup Environ Health 82:787-94. 2009
    ..To examine the immune response to job strain and insecurity of 88 men working in a university, divided according to age and type of employment...
  33. ncbi The effect of deproteinized bovine bone on osteoblast growth factors and proinflammatory cytokine production
    Paolo Amerio
    Department of Oncology and Neuroscience, University of Chieti Pescara, Chieti, Italy
    Clin Oral Implants Res 21:650-5. 2010
    ..To test the ability of Bio-Oss in inducing growth factors and proinflammatory cytokines that may have a role in inflammation after grafting, bone resorption, remodeling and in the homeostasis of osteoblasts...
  34. ncbi Effects of resveratrol on lymphocyte proliferation and cytokine release
    Paolo Boscolo
    Department of Medicine and Science of Aging, University G D Annunzio, Chieti, Italy
    Ann Clin Lab Sci 33:226-31. 2003
    ..However, a stimulatory effect of low concentrations of resveratrol on the immune system cannot be excluded...
  35. ncbi Interleukin-6 and mast cells
    Pio Conti
    University of Chieti School of Medicine, Via dei Vestini, 66100 Chieti, Italy
    Allergy Asthma Proc 23:331-5. 2002
    ..IL-6 also up-regulates histamine production rather than increases its storage and is an important inducing factor for the expression of immunoglobulin E (IgE) Fc epsilon RI...
  36. ncbi Inhibition of MCP-1 and MIP-2 transcription and translation by mimosine in muscle tissue infected with the parasite Trichinella spiralis
    Pio Conti
    Department of Oncology and Neurosciences, University of Chieti, Italy
    Mol Cell Biochem 229:129-37. 2002
    ..This study suggests for the first time the premise that mimosine acts as an anti-inflammatory compound...
  37. ncbi In vitro effects of nickel-sulphate on immune functions of normal and nickel-allergic subjects: a regulatory role for zinc
    Roberto Paganelli
    Department of Medicine, University, G D Annunzio, Chieti, Italy
    J Trace Elem Med Biol 17:11-5. 2003
    ..Our data are consistent with the hypothesis that Zn and Ni, as part of the heavy transition metals, may exchange roles in immune-mediated phenomena leading to expression of allergic contact dermatitis...
  38. ncbi Differential production of RANTES and MCP-1 in synovial fluid from the inflamed human knee
    Pio Conti
    Immunology Division, University of Chieti School of Medicine, Via dei Vestini, 66013 Chieti, Italy
    Immunol Lett 80:105-11. 2002
    ....
  39. ncbi Alzheimer patients treated with an AchE inhibitor show higher IL-4 and lower IL-1 beta levels and expression in peripheral blood mononuclear cells
    Francesco Gambi
    Psychiatry Unit, Department of Oncology and Neuroscience, University G D Annunzio, Via dei Vestini, 66013 Chieti, Italy
    J Clin Psychopharmacol 24:314-21. 2004
    ..This increment was observed in both unstimulated and phytohemagglutinin-stimulated peripheral blood mononuclear cells...
  40. ncbi In vitro effects of platinum compounds on lymphocyte proliferation and cytokine release
    Mario Di Gioacchino
    Department of Medicine and Science of Ageing, G D Annunzio University of Chieti, Italy
    Ann Clin Lab Sci 34:195-202. 2004
    ..These results indicate that certain Pt salts affect lymphocyte proliferation and cytokine release. The intracellular mechanisms responsible for such effects have not been identified...
  41. ncbi Different effects of platinum, palladium, and rhodium salts on lymphocyte proliferation and cytokine release
    Paolo Boscolo
    Department of Medicine and Science of Ageing, G D Annunzio University of Chieti and Pescara, Italy
    Ann Clin Lab Sci 34:299-306. 2004
    ....
  42. ncbi Inhibitory effects of cadmium on peripheral blood mononuclear cell proliferation and cytokine release are reversed by zinc and selenium salts
    Paolo Boscolo
    Department of Medicine and Sciences of Ageing, University G D Annunzio, Chieti, Italy
    Ann Clin Lab Sci 35:115-20. 2005
    ..This suggests that dietary excess of Se may not have beneficial effects...
  43. ncbi In vitro effects of vanadate on human immune functions
    Mario Di Gioacchino
    Department of Medicine and Science of Aging, Section of Allergy, Clinical Immunology, and Occupational Medicine, G d Annunzio University School of Medicine, Chieti, Italy
    Ann Clin Lab Sci 32:148-54. 2002
    ..This investigation suggests that environmental V can have important effects on the human immune system...
  44. ncbi Oxygen supply modulates MCP-1 release in monocytes from young and aged rats: decrease of MCP-1 transcription and translation is age-related
    M Reale
    Immunology Division, Department of Oncology and Neurosciences, School of Medicine, University of Chieti, Chieti, Italy
    Mol Cell Biochem 248:1-6. 2003
    ....
  45. ncbi "In vitro" comparative immune effects of different titanium compounds
    L Di Giampaolo
    Department of Medicine and Science or Ageing, Section of Occupational Medicine, Allergy and Clinical Immunology, G. D'Annunzio University, Chieti, Italy
    Int J Immunopathol Pharmacol 17:115-22. 2004
    ..In conclusion, the data show that immunotoxicity fo Ti depends on speciation...
  46. ncbi The immune response of women with prolonged exposure to electromagnetic fields produced by radiotelevision broadcasting stations
    P Boscolo
    Operative Unit of Occupational Medicine of the University of Chieti, Pescara, Chieti, Italy
    Int J Immunopathol Pharmacol 19:43-8. 2006
    ..An effect of EMFs on immune functions, in part mediated by nervous mechanisms, may be hypothesized. However, the influence of lifestyle may not be excluded...
  47. ncbi Elevated circulating levels of monocyte chemoattractant protein-1 in patients with restenosis after coronary angioplasty
    F Cipollone
    Department of Medicine and Aging, University of Chieti G D'Annunzio School of Medicine, Chieti, Italy
    Arterioscler Thromb Vasc Biol 21:327-34. 2001
    ..Further understanding of the mechanism(s) by which MCP-1 is produced and acts after arterial injury may provide insight into therapies to limit the progression of atherosclerosis and restenosis after balloon angioplasty...
  48. ncbi Intramuscular injection of hrRANTES causes mast cell recruitment and increased transcription of histidine decarboxylase in mice: lack of effects in genetically mast cell-deficient W/WV mice
    P Conti
    Immunology Division, University of Chieti School of Medicine, Chieti, Italy
    FASEB J 12:1693-700. 1998
    ..In these studies, hrRANTES injections in muscle tissue provided direct in vivo evidence that RANTES has a significant effect on mast cell recruitment and HDC mRNA generation...
  49. ncbi Interleukin-16 network in inflammation and allergy
    Pio Conti
    Immunology Division, University of Chieti, Via dei Vestini, Chieti, Italy
    Allergy Asthma Proc 23:103-8. 2002
    ..In accordance with other data in the medical literature, we conclude that the most important function of IL-16 is the chemoattraction of CD4+ cells...
  50. ncbi Production of MCP-1 and RANTES in bladder cancer patients after bacillus Calmette-Guerin immunotherapy
    Marcella Reale
    Immunology Division, University of Chieti, Medical School, Via dei Vestini, 66013 Chieti, Italy
    Cancer Immunol Immunother 51:91-8. 2002
    ..The anti-tumor effects of BCG observed in superficial bladder cancer therapy may depend on stimulation of the investigated chemokines, which attract monocytes/macrophages and memory T cells...
  51. ncbi MCP-1 and MIP-2 expression and production in BB diabetic rat: effect of chronic hypoxia
    Cacchio Marisa
    Department of Biomedical Sciences, University G D Annunzio, Chieti, Italy
    Mol Cell Biochem 276:105-11. 2005
    ..1+/- 72). Our data point to MCP-1 and MIP-2 as important components in the pathophysiology of diabetes, and hypoxia is an important and potent environmental stimulus capable of modulating the expression and production of these chemokines...
  52. ncbi Interferon beta-1b modulates MCP-1 expression and production in relapsing-remitting multiple sclerosis
    Carla Iarlori
    Department of Oncology and Neuroscience, Neuroimmunology Unit, University G. D'Annunzio, Via dei Vestini, I-66013, Chieti, Italy
    J Neuroimmunol 123:170-9. 2002
    ..Logistic regression analysis shows that MCP-1 production is significantly modified by treatment. Further studies are needed to clarify the role of MCP-1 in MS...
  53. ncbi MCP-1 and MIP-2 response in Trichinella spiralis infected mice treated with 4-deoxypyridoxine (4-DPD)
    Stavros Frydas
    Department of Parasitology, Veterinary Faculty, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Immunol Lett 83:31-7. 2002
    ..This study demonstrates that MIP-2 and MCP-1 are stimulated in serum and tissue of T. spiralis infected mice and 4-DPD-treated animals significantly inhibited them...
  54. ncbi IL-4 in vitro production is upregulated in Alzheimer's disease patients treated with acetylcholinesterase inhibitors
    Alessandra Lugaresi
    Department of Oncology and Neurosciences, Section of Neurology, University G. D'Annunzio Chieti, Italy
    Exp Gerontol 39:653-7. 2004
    ..The increased production of IL-4 in AChEI treated patients might represent an additional mechanism through which AChEI act on AD progression...