Research Topics
Genomes and GenesSpecies | G RavagliaSummaryAffiliation: University of Bologna Country: Italy Publications
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Detail Information
Publications
The conselice study of brain ageingGiovanni Ravaglia
Department of Internal Medicine, Ageing, and Nephrology, University of Bologna, University Hospital S, Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Immun Ageing 7:S2. 2010..These data have been used to estimate prevalence and incidence of dementia in the elderly Italian population and to investigate the possible role of baseline blood homocysteine as risk factors for dementia...
The clock-drawing test in elderly Italian community dwellers: associations with sociodemographic status and risk factors for vascular cognitive impairmentG Ravaglia
Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
Dement Geriatr Cogn Disord 16:287-95. 2003..This study shows that in elderly community dwellers, CDT may be not totally free from sociodemographic biases, and that it is associated with risk factors for cognitive impairment and frailty...
Prevalent depressive symptoms as a risk factor for conversion to mild cognitive impairment in an elderly Italian cohortGiovanni Ravaglia
Department of Internal Medicine, Ageing, and Nephrology, University Hospital S Orsola Malpighi, University of Bologna, Italy
Am J Geriatr Psychiatry 16:834-43. 2008..To examine the association between depressive symptoms and prevalent and incident mild cognitive impairment (MCI) in elderly individuals; to verify whether it is affected by MCI subtype...
Physical activity and dementia risk in the elderly: findings from a prospective Italian studyG Ravaglia
Department of Internal Medicine, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
Neurology 70:1786-94. 2008..To examine the effect of physical activity on risk of developing Alzheimer disease (AD) and vascular dementia (VaD) in the elderly...
Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged >/=90 yG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, the Department of Angiology and Blood Coagulation, and the Division of Geriatric Medicine, University Hospital Sant Orsola Malpighi, Bologna, Italy
Am J Clin Nutr 71:590-8. 2000..Natural killer (NK) cells play a role in natural immunity against tumor and infected cells. Advanced aging is associated with functional impairment of NK cells and increased susceptibility to nutritional deficiencies...
Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjectsG Ravaglia
Center for the Study of Fisiopathology of Ageing, University of Bologna, Italy
J Nutr Health Aging 4:218-22. 2000..In conclusion, although a relationship between homocysteine, B vitamins and poor cognitive skills in the elderly is plausible, this study does not suggests that such relationship is biologically important...
Incidence and etiology of dementia in a large elderly Italian populationG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
Neurology 64:1525-30. 2005....
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairmentG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Mech Ageing Dev 121:251-61. 2000..Previous reports have shown elevated plasma total homocysteine (tHcy) levels in elderly person with impaired cognition...
Atrial fibrillation and risk of dementia in non-demented elderly subjects with and without mild cognitive impairment (MCI)P Forti
Department of Internal Medicine, Cardioangiology, and Hepatology University Hospital S Orsola Malpighi, Via Massarenti, 9, I 40138 Bologna, Italy
Arch Gerontol Geriatr 44:155-65. 2007..10, 95% Cl=0.40-3.03). Current diagnostic criteria for MCI subtypes define heterogeneous populations, but atrial fibrillation can be useful in identifying people with increased risk of conversion to dementia...
Measurement of body fat in healthy elderly men: a comparison of methodsG Ravaglia
Department of Internal Medicine, Cardioangiology, and Epatology, St Orsola Hospital, University of Bologna, Italy
J Gerontol A Biol Sci Med Sci 54:M70-6. 1999..In this study, percent body fat (%BF) estimates from anthropometry and BIA in men of various ages were compared with corresponding measurements by DXA...
Risk factors for dementia: data from the Conselice study of brain agingG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology University Hospital S Orsola Malpighi, Bologna, Italy
Arch Gerontol Geriatr 44:311-20. 2007..These data have been used to estimate prevalence and incidence of dementia in the elderly Italian population and to investigate the possible role of homocysteine as a predictor of dementia...
Peripheral blood markers of inflammation and functional impairment in elderly community-dwellersG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Exp Gerontol 39:1415-22. 2004..A specific combination of CRP with other markers provides a better correlate of functional impairment than both individual markers or a simple count of positive markers...
Natural immunity and bone and muscle remodelling hormones in the elderlyE Mariani
Laboratorio di Immunologia e Genetica, Istituto Codivilla Putti IOR, Bologna, Italy
Mech Ageing Dev 102:279-92. 1998..The magnitude of the NK immune response, which constitutes the first line of defence against infected and neoplastic cells, is best preserved in oldest-old people with the best hormonal parameters and nutritional measures...
Vitamin D, thyroid hormones and muscle mass influence natural killer (NK) innate immunity in healthy nonagenarians and centenariansE Mariani
Laboratorio di Immunologia e Genetica, University of Bologna, Italy
Clin Exp Immunol 116:19-27. 1999..In conclusion, our results stress the paramount importance of nutritional evaluation in the clinical assessment of elderly people...
Blood micronutrient and thyroid hormone concentrations in the oldest-oldG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
J Clin Endocrinol Metab 85:2260-5. 2000..011). In younger subjects, no significant association was found among thyroid variables and micronutrients. In conclusion, blood levels of specific micronutrients are associated with serum iodothyronine levels in extreme aging...
Body composition, sex steroids, IGF-1, and bone mineral status in aging menG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, S Orsola Malpighi Hospital, University of Bologna, Italy
J Gerontol A Biol Sci Med Sci 55:M516-21. 2000..The independent influences of body composition and endocrine factors on male bone metabolism, however, are unclear...
Atrial fibrillation and risk of dementia in non-demented elderly subjects with and without mild cognitive impairmentPaola Forti
Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S. Orsola-Malpighi, 40138 Bologna, Italy
Neurol Res 28:625-9. 2006..10; 95% confidence interval: 0.40-3.03). DISCUSSION: Current diagnostic criteria for MCI subtypes define heterogeneous populations, but atrial fibrillation can be useful in identifying people with increased risk of conversion to dementia...
Comparison of two frailty measures in the Conselice Study of Brain AgeingA Lucicesare
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital Sant Orsola Malpighi, University of Bologna, Bologna, Italy
J Nutr Health Aging 14:278-81. 2010..Uncertainty about the definition of frailty is reflected by the development of many ways to identify frail people. We aimed to compare the validity of two frailty measures in participants of the Conselice Study of Brain Aging...
Elevated plasma levels of alpha-1-anti-chymotrypsin in age-related cognitive decline and Alzheimer's disease: a potential therapeutic targetE Porcellini
Department of Experimental Pathology, School of Medicine, University of Bologna, Via S Giacomo 14, 40126 Bologna, Italy
Curr Pharm Des 14:2659-64. 2008..The development of compounds able to interfere with the ACT biological activity (protease inhibition and/or promotion of amyloid deposition) might have therapeutic relevance for the disease...
Regular moderate intensity physical activity and blood concentrations of endogenous anabolic hormones and thyroid hormones in aging menG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Mech Ageing Dev 122:191-203. 2001..Physical activity has been reported to affect endocrine function in elderly men...
Coeliac disease in patients with autoimmune thyroiditisU Volta
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Polyclinic, Bologna, Italy
Digestion 64:61-5. 2001..The close association between coeliac disease and autoimmunity prompted us to perform an antibody screening for gluten-sensitive enteropathy in patients with autoimmune thyroid dysfunction...
Serum concentrations of zinc and selenium in elderly people: results in healthy nonagenarians/centenariansL Savarino
Laboratorio di Fisiopatologia degli Impianti Ortopedici, Istituti Ortopedici Rizzoli, Via Di Barbiano 1 10, 40136, Bologna, Italy
Exp Gerontol 36:327-39. 2001..Consequently, a prospective and follow-up evaluation of Zn and Se could be proposed as a good index for a correct monitoring of the micronutrient deficiencies, that could represent an early sign of disease...
Plasma homocysteine and inflammation in elderly patients with cardiovascular disease and dementiaG Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S. Orsola-Malpighi, Bologna 40138, Italy
Exp Gerontol 39:443-50. 2004..The results suggest that the association between plasma tHcy and sCRP is more an aspecific reflection of poor health than a specific correlate of vascular inflammation...
Different IL-8 production by T and NK lymphocytes in elderly subjectsE Mariani
Dipartimento di Medicina Interna e Gastroenterologia, University of Bologna, Bologna, Italy
Mech Ageing Dev 122:1383-95. 2001....
Development of acute psychotic disorders and HIV-1 infectionD De Ronchi
Institute of Psychiatry, Medical School, University of Bologna, Italy
Int J Psychiatry Med 30:173-83. 2000....
A comparison of acute phase proteins and traditional risk factors as markers of combined plaque and intima-media thickness and plaque density in carotid and femoral arteriesA Muscari
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
Eur J Vasc Endovasc Surg 26:81-7. 2003..CRP was associated with high density femoral plaques. Finally, no acute phase protein was independently associated with low density, potentially vulnerable, plaques...
