G Ravaglia

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi Conversion of mild cognitive impairment to dementia: predictive role of mild cognitive impairment subtypes and vascular risk factors
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Dement Geriatr Cogn Disord 21:51-8. 2006
  2. ncbi Interleukin-1beta and interleukin-6 gene polymorphisms as risk factors for AD: a prospective study
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    Exp Gerontol 41:85-92. 2006
  3. ncbi Screening for mild cognitive impairment in elderly ambulatory patients with cognitive complaints
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Aging Clin Exp Res 17:374-9. 2005
  4. ncbi Associations of the -174 G/C interleukin-6 gene promoter polymorphism with serum interleukin 6 and mortality in the elderly
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138, Bologna, Italy
    Biogerontology 6:415-23. 2005
  5. ncbi Blood inflammatory markers and risk of dementia: The Conselice Study of Brain Aging
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, 40138 Bologna, Italy
    Neurobiol Aging 28:1810-20. 2007
  6. ncbi Plasma amino acid concentrations in healthy and cognitively impaired oldest-old individuals: associations with anthropometric parameters of body composition and functional disability
    Giovanni Ravaglia
    Department of Internal Medicine, University Hospital S Orsola Malpighi, Bologna, Italy
    Br J Nutr 88:563-72. 2002
  7. ncbi Education, occupation, and prevalence of dementia: findings from the Conselice study
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Dement Geriatr Cogn Disord 14:90-100. 2002
  8. ncbi Homocysteine and cognitive function in healthy elderly community dwellers in Italy
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Am J Clin Nutr 77:668-73. 2003
  9. ncbi Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, Bologna, Italy
    Exp Gerontol 37:701-12. 2002
  10. ncbi Increased prevalence of coeliac disease in autoimmune thyroiditis is restricted to aged patients
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, Bologna 40138, Italy
    Exp Gerontol 38:589-95. 2003

Collaborators

Detail Information

Publications53

  1. ncbi Conversion of mild cognitive impairment to dementia: predictive role of mild cognitive impairment subtypes and vascular risk factors
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Dement Geriatr Cogn Disord 21:51-8. 2006
    ..Our results show that current diagnostic criteria for MCI define heterogeneous populations, but some potentially treatable vascular risk factors may be of help in predicting conversion to dementia...
  2. ncbi Interleukin-1beta and interleukin-6 gene polymorphisms as risk factors for AD: a prospective study
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    Exp Gerontol 41:85-92. 2006
    ..The relationship between the AD risk factor plasma tHcy and the IL-1beta-511 polymorphism was never reported before and might explain previous cross-sectional reports of an association between this polymorphism and AD...
  3. ncbi Screening for mild cognitive impairment in elderly ambulatory patients with cognitive complaints
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Aging Clin Exp Res 17:374-9. 2005
    ..Two brief global cognitive instruments, the Mini Mental State Examination (MMSE) and the Clock Drawing Test (CDT), were examined as useful screening methods for MCI...
  4. ncbi Associations of the -174 G/C interleukin-6 gene promoter polymorphism with serum interleukin 6 and mortality in the elderly
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138, Bologna, Italy
    Biogerontology 6:415-23. 2005
    ..31, 95%CI: 0.13-0.76]. In conclusion, although associated with increased sIL6 levels in presence of major diseases, the IL6-174 C-allele does not seem to have direct detrimental effects on survival in older age...
  5. ncbi Blood inflammatory markers and risk of dementia: The Conselice Study of Brain Aging
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, 40138 Bologna, Italy
    Neurobiol Aging 28:1810-20. 2007
    ..91; 95%CI, 1.02-3.56) but not VaD risk. Blood inflammatory markers are associated with increased VaD risk but do not predict AD, which seems selectively associated with hyperhomocysteinemia...
  6. ncbi Plasma amino acid concentrations in healthy and cognitively impaired oldest-old individuals: associations with anthropometric parameters of body composition and functional disability
    Giovanni Ravaglia
    Department of Internal Medicine, University Hospital S Orsola Malpighi, Bologna, Italy
    Br J Nutr 88:563-72. 2002
    ....
  7. ncbi Education, occupation, and prevalence of dementia: findings from the Conselice study
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Dement Geriatr Cogn Disord 14:90-100. 2002
    ..After adjustment for age and gender, education but not occupation was associated with both AD and VD. This association could not be explained by occupation, life habits, and previous history of hypertension or cardiovascular disease...
  8. ncbi Homocysteine and cognitive function in healthy elderly community dwellers in Italy
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Am J Clin Nutr 77:668-73. 2003
    ..Elevated plasma total homocysteine (tHcy) concentrations are common in the elderly and have been suggested to be a risk factor for dementia...
  9. ncbi Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, Bologna, Italy
    Exp Gerontol 37:701-12. 2002
    ..These data suggest that in elderly people low serum DHEAS levels are more a non-specific indicator of aging and health status than a risk indicator of specific diseases...
  10. ncbi Increased prevalence of coeliac disease in autoimmune thyroiditis is restricted to aged patients
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, Bologna 40138, Italy
    Exp Gerontol 38:589-95. 2003
    ..In conclusion, prevalence of CD is increased in AT but the association is limited to patients aged 65 years or older. Serological screening including anti-tTG-IgA is recommended in these patients...
  11. ncbi Plasma amino acid concentrations in patients with amnestic mild cognitive impairment or Alzheimer disease
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Am J Clin Nutr 80:483-8. 2004
    ....
  12. ncbi Regular moderate intensity physical activity and blood concentrations of endogenous anabolic hormones and thyroid hormones in aging men
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Mech Ageing Dev 122:191-203. 2001
    ..Physical activity has been reported to affect endocrine function in elderly men...
  13. ncbi Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Mech Ageing Dev 121:251-61. 2000
    ..Previous reports have shown elevated plasma total homocysteine (tHcy) levels in elderly person with impaired cognition...
  14. ncbi Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjects
    G Ravaglia
    Center for the Study of Fisiopathology of Ageing, University of Bologna, Italy
    J Nutr Health Aging 4:218-22. 2000
    ..In conclusion, although a relationship between homocysteine, B vitamins and poor cognitive skills in the elderly is plausible, this study does not suggests that such relationship is biologically important...
  15. ncbi Body composition, sex steroids, IGF-1, and bone mineral status in aging men
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, S Orsola Malpighi Hospital, University of Bologna, Italy
    J Gerontol A Biol Sci Med Sci 55:M516-21. 2000
    ..The independent influences of body composition and endocrine factors on male bone metabolism, however, are unclear...
  16. ncbi Blood micronutrient and thyroid hormone concentrations in the oldest-old
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    J Clin Endocrinol Metab 85:2260-5. 2000
    ..011). In younger subjects, no significant association was found among thyroid variables and micronutrients. In conclusion, blood levels of specific micronutrients are associated with serum iodothyronine levels in extreme aging...
  17. ncbi Measurement of body fat in healthy elderly men: a comparison of methods
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Epatology, St Orsola Hospital, University of Bologna, Italy
    J Gerontol A Biol Sci Med Sci 54:M70-6. 1999
    ..In this study, percent body fat (%BF) estimates from anthropometry and BIA in men of various ages were compared with corresponding measurements by DXA...
  18. ncbi Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged >/=90 y
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, the Department of Angiology and Blood Coagulation, and the Division of Geriatric Medicine, University Hospital Sant Orsola Malpighi, Bologna, Italy
    Am J Clin Nutr 71:590-8. 2000
    ..Natural killer (NK) cells play a role in natural immunity against tumor and infected cells. Advanced aging is associated with functional impairment of NK cells and increased susceptibility to nutritional deficiencies...
  19. ncbi Physical activity and dementia risk in the elderly: findings from a prospective Italian study
    G Ravaglia
    Department of Internal Medicine, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    Neurology 70:1786-94. 2008
    ..To examine the effect of physical activity on risk of developing Alzheimer disease (AD) and vascular dementia (VaD) in the elderly...
  20. ncbi Peripheral blood markers of inflammation and functional impairment in elderly community-dwellers
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Exp Gerontol 39:1415-22. 2004
    ..A specific combination of CRP with other markers provides a better correlate of functional impairment than both individual markers or a simple count of positive markers...
  21. pmc Vitamin D, thyroid hormones and muscle mass influence natural killer (NK) innate immunity in healthy nonagenarians and centenarians
    E Mariani
    Laboratorio di Immunologia e Genetica, University of Bologna, Italy
    Clin Exp Immunol 116:19-27. 1999
    ..In conclusion, our results stress the paramount importance of nutritional evaluation in the clinical assessment of elderly people...
  22. ncbi Risk factors for dementia: data from the Conselice study of brain aging
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology University Hospital S Orsola Malpighi, Bologna, Italy
    Arch Gerontol Geriatr 44:311-20. 2007
    ..These data have been used to estimate prevalence and incidence of dementia in the elderly Italian population and to investigate the possible role of homocysteine as a predictor of dementia...
  23. ncbi Incidence and etiology of dementia in a large elderly Italian population
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    Neurology 64:1525-30. 2005
    ....
  24. ncbi Natural immunity and bone and muscle remodelling hormones in the elderly
    E Mariani
    Laboratorio di Immunologia e Genetica, Istituto Codivilla Putti IOR, Bologna, Italy
    Mech Ageing Dev 102:279-92. 1998
    ..The magnitude of the NK immune response, which constitutes the first line of defence against infected and neoplastic cells, is best preserved in oldest-old people with the best hormonal parameters and nutritional measures...
  25. ncbi Atrial fibrillation and risk of dementia in non-demented elderly subjects with and without mild cognitive impairment (MCI)
    P Forti
    Department of Internal Medicine, Cardioangiology, and Hepatology University Hospital S Orsola Malpighi, Via Massarenti, 9, I 40138 Bologna, Italy
    Arch Gerontol Geriatr 44:155-65. 2007
    ..10, 95% Cl=0.40-3.03). Current diagnostic criteria for MCI subtypes define heterogeneous populations, but atrial fibrillation can be useful in identifying people with increased risk of conversion to dementia...
  26. ncbi Plasma homocysteine and inflammation in elderly patients with cardiovascular disease and dementia
    G Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna 40138, Italy
    Exp Gerontol 39:443-50. 2004
    ..The results suggest that the association between plasma tHcy and sCRP is more an aspecific reflection of poor health than a specific correlate of vascular inflammation...
  27. ncbi Coeliac disease in patients with autoimmune thyroiditis
    U Volta
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Polyclinic, Bologna, Italy
    Digestion 64:61-5. 2001
    ..The close association between coeliac disease and autoimmunity prompted us to perform an antibody screening for gluten-sensitive enteropathy in patients with autoimmune thyroid dysfunction...
  28. ncbi Serum concentrations of zinc and selenium in elderly people: results in healthy nonagenarians/centenarians
    L Savarino
    Laboratorio di Fisiopatologia degli Impianti Ortopedici, Istituti Ortopedici Rizzoli, Via Di Barbiano 1 10, 40136, Bologna, Italy
    Exp Gerontol 36:327-39. 2001
    ..Consequently, a prospective and follow-up evaluation of Zn and Se could be proposed as a good index for a correct monitoring of the micronutrient deficiencies, that could represent an early sign of disease...
  29. ncbi Elevated plasma levels of alpha-1-anti-chymotrypsin in age-related cognitive decline and Alzheimer's disease: a potential therapeutic target
    E Porcellini
    Department of Experimental Pathology, School of Medicine, University of Bologna, Via S Giacomo 14, 40126 Bologna, Italy
    Curr Pharm Des 14:2659-64. 2008
    ..The development of compounds able to interfere with the ACT biological activity (protease inhibition and/or promotion of amyloid deposition) might have therapeutic relevance for the disease...
  30. ncbi Comparison of two frailty measures in the Conselice Study of Brain Ageing
    A Lucicesare
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital Sant Orsola Malpighi, University of Bologna, Bologna, Italy
    J Nutr Health Aging 14:278-81. 2010
    ..Uncertainty about the definition of frailty is reflected by the development of many ways to identify frail people. We aimed to compare the validity of two frailty measures in participants of the Conselice Study of Brain Aging...
  31. ncbi The clock-drawing test in elderly Italian community dwellers: associations with sociodemographic status and risk factors for vascular cognitive impairment
    G Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Dement Geriatr Cogn Disord 16:287-95. 2003
    ..This study shows that in elderly community dwellers, CDT may be not totally free from sociodemographic biases, and that it is associated with risk factors for cognitive impairment and frailty...
  32. ncbi Atrial fibrillation and risk of dementia in non-demented elderly subjects with and without mild cognitive impairment
    Paola Forti
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, 40138 Bologna, Italy
    Neurol Res 28:625-9. 2006
    ....
  33. ncbi Different IL-8 production by T and NK lymphocytes in elderly subjects
    E Mariani
    Dipartimento di Medicina Interna e Gastroenterologia, University of Bologna, Bologna, Italy
    Mech Ageing Dev 122:1383-95. 2001
    ....
  34. ncbi Development of acute psychotic disorders and HIV-1 infection
    D De Ronchi
    Institute of Psychiatry, Medical School, University of Bologna, Italy
    Int J Psychiatry Med 30:173-83. 2000
    ....
  35. ncbi A comparison of acute phase proteins and traditional risk factors as markers of combined plaque and intima-media thickness and plaque density in carotid and femoral arteries
    A Muscari
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
    Eur J Vasc Endovasc Surg 26:81-7. 2003
    ..To test the hypothesis that some acute phase proteins may be better independent predictors of objective measures of arterial wall impairment than traditional risk factors...
  36. ncbi Metabolic Syndrome: prevalence and prediction of mortality in elderly individuals
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University of Bologna, Via Massarenti, 9 40138 Bologna, Italy
    Diabetes Care 29:2471-6. 2006
    ....
  37. ncbi Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Am J Clin Nutr 84:1473-80. 2006
    ..Homocysteine, another risk factor for vascular disease and dementia, also binds to VLDL in blood. However, the association between APOE4 and hyperhomocysteinemia has never been thoroughly investigated...
  38. ncbi Mild cognitive impairment: epidemiology and dementia risk in an elderly Italian population
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    J Am Geriatr Soc 56:51-8. 2008
    ..To investigate prevalence and incidence of mild cognitive impairment (MCI) and its risk of progression to dementia in an elderly Italian population...
  39. ncbi Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status
    Erminia Mariani
    Laboratorio di Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, IOR, Via Di Barbiano 1 10, 40136, Bologna, Italy
    Biogerontology 7:449-59. 2006
    ....
  40. ncbi Endogenous sex hormones as risk factors for dementia in elderly men and women
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola, Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    J Gerontol A Biol Sci Med Sci 62:1035-41. 2007
    ..The associations of endogenous sex hormones with risk of dementia in the elderly population are not well known...
  41. doi Development of an easy prognostic score for frailty outcomes in the aged
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Age Ageing 37:161-6. 2008
    ..identification of frailty is recommended in geriatric practice. However, there is a lack of frailty scores combining easy-to-collect predictors from multiple domains...
  42. ncbi Plasma tocopherols and risk of cognitive impairment in an elderly Italian cohort
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital Sant Orsola Malpighi, University of Bologna, Bologna, Italy
    Am J Clin Nutr 87:1306-13. 2008
    ..The most abundant and most investigated form of vitamin E in humans is alpha-tocopherol, but other antioxidant tocopherols (beta, gamma, and delta) exist in nature...
  43. ncbi Chemokine production by natural killer cells from nonagenarians
    Erminia Mariani
    Laboratorio di Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, IOR, Bologna, Italy
    Eur J Immunol 32:1524-9. 2002
    ....
  44. ncbi Telomere length and telomerase activity: effect of ageing on human NK cells
    Erminia Mariani
    Laboratorio di Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, I O R, Via Di Barbiano 1 10, 40136, Bologna, Italy
    Mech Ageing Dev 124:403-8. 2003
    ....
  45. ncbi Different rates of telomere shortening and telomerase activity reduction in CD8 T and CD16 NK lymphocytes with ageing
    Erminia Mariani
    Laboratorio di Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, I O R, Via Di Barbiano 1 10, 40136, Bologna, Italy
    Exp Gerontol 38:653-9. 2003
    ..We can assume that preserved innate immune response in the elderly is due to the negligible telomere shortening and the maintained telomerase expression that could allow NK cells of octogenarians to delay replicative senescence...
  46. ncbi Different classification systems yield different dementia occurrence among nonagenarians and centenarians
    Philippe Pioggiosi
    Institute of Psychiatry, University of Bologna, Bologna, Italy
    Dement Geriatr Cogn Disord 17:35-41. 2004
    ..In this light, classification systems, such as the ICD-10, that do not include impairment of social function as a criterion for assessing dementia become less adequate...
  47. ncbi Soluble receptor activator of nuclear factor- kappaB Ligand (sRANKL)/osteoprotegerin balance in ageing and age-associated diseases
    Lia Pulsatelli
    Laboratorio Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, Istituti Ortopedici Rizzoli, Bologna, Italy
    Biogerontology 5:119-27. 2004
    ..Hence, in ageing, the sRANKL/OPG system appears to be modified, with prominent changes in circulating OPG levels; in OA and PMR, the sRANKL/OPG balance alteration was shown to be mainly due to the increase of plasma sRANKL concentration...
  48. ncbi Effects of weight loss and risk factor treatment in subjects with elevated serum C3, an inflammatory predictor of myocardial infarction
    Antonio Muscari
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, M Malpighi Hospital Via Albertoni, Italy
    Int J Cardiol 100:217-23. 2005
    ..Serum C3 is an inflammatory predictor of myocardial infarction and a covariate of fasting insulin and several endogenous risk factors. This study was performed to ascertain whether risk factor control may reduce elevated C3 concentrations...
  49. ncbi Mismatch repair system and aging: microsatellite instability in peripheral blood cells from differently aged participants
    Simona Neri
    Laboratorio di Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, IOR, Bologna, Italy
    J Gerontol A Biol Sci Med Sci 60:285-92. 2005
    ....
  50. ncbi Serum C-reactive protein and cognitive function in healthy elderly Italian community dwellers
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    J Gerontol A Biol Sci Med Sci 60:1017-21. 2005
    ..Chronic low-grade inflammation, as measured with the peripheral serum marker C-reactive protein (sCRP), may be a risk factor for dementia in elderly persons...
  51. ncbi Homocysteine and folate as risk factors for dementia and Alzheimer disease
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
    Am J Clin Nutr 82:636-43. 2005
    ..In cross-sectional studies, elevated plasma total homocysteine (tHcy) concentrations have been associated with cognitive impairment and dementia. Incidence studies of this issue are few and have produced conflicting results...
  52. ncbi Folate, but not homocysteine, predicts the risk of fracture in elderly persons
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology, and Hepatology University Hospital S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    J Gerontol A Biol Sci Med Sci 60:1458-62. 2005
    ..These studies, however, did not take into account folate and vitamin B12, which are the major nutritional determinants of homocysteinemia...
  53. ncbi RANTES and MIP-1alpha production by T lymphocytes, monocytes and NK cells from nonagenarian subjects
    Erminia Mariani
    Laboratorio di Immunologia e Genetica, Istituto di Ricerca Codivilla Putti, IOR Bologna, Dipartimento di Medicina Interna e Gastroenterologia, University of Bologna, Via Di Barbiano 1 10, 40136 Bologna, Italy
    Exp Gerontol 37:219-26. 2002
    ..The diversity within PBMC might reflect their different states of activation and/or responsiveness, influencing the ability to develop rapid innate and long-lasting adaptive immune responses...