Innocenzo Rainero

Summary

Affiliation: University of Turin
Country: Italy

Publications

  1. pmc Anger and emotional distress in patients with migraine and tension-type headache
    Paolo Perozzo
    Fondazione Carlo Molo, CE R NE, Turin, Italy
    J Headache Pain 6:392-9. 2005
  2. pmc Conversion from migraine without aura to typical aura without headache after irbesartan
    L Pinessi
    J Headache Pain 6:100. 2005
  3. doi request reprint Hypocretins and primary headaches: neurobiology and clinical implications
    Innocenzo Rainero
    Neurology II Headache Centre, Department of Neuroscience, University of Turin, Via Cherasco 15 10126, Torino, Italy
    Expert Rev Neurother 8:409-16. 2008
  4. ncbi request reprint Association between the tumor necrosis factor-alpha -308 G/A gene polymorphism and migraine
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Italy
    Neurology 62:141-3. 2004
  5. ncbi request reprint Haemochromatosis gene (HFE) polymorphisms and migraine: an association study
    I Rainero
    Neurology II, Headache Centre, Department of Neuroscience, University of Torino, Torino, Italy
    Cephalalgia 27:9-13. 2007
  6. ncbi request reprint Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Via Cherasco, 15 10126 Torino, Italy
    Neurobiol Aging 25:1293-8. 2004
  7. ncbi request reprint A polymorphism of the hypocretin receptor 2 gene is associated with cluster headache
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Via Cherasco 15 10126 Turin, Italy
    Neurology 63:1286-8. 2004
  8. ncbi request reprint Insulin sensitivity is impaired in patients with migraine
    I Rainero
    Neurology III Headache Centre, Department of Neuroscience, University of Turin, Italy
    Cephalalgia 25:593-7. 2005
  9. ncbi request reprint Lack of association between the 3092 T-->C Clock gene polymorphism and cluster headache
    I Rainero
    Neurology III, Headache Centre, Department of Neuroscience, University of Torino, Torino, Italy
    Cephalalgia 25:1078-81. 2005
  10. ncbi request reprint HLA-DRB1 genotyping in Italian migraine patients
    Innocenzo Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Via Cherasco 15, Torino 10126, Italy
    Neurosci Lett 393:90-3. 2006

Detail Information

Publications63

  1. pmc Anger and emotional distress in patients with migraine and tension-type headache
    Paolo Perozzo
    Fondazione Carlo Molo, CE R NE, Turin, Italy
    J Headache Pain 6:392-9. 2005
    ....
  2. pmc Conversion from migraine without aura to typical aura without headache after irbesartan
    L Pinessi
    J Headache Pain 6:100. 2005
  3. doi request reprint Hypocretins and primary headaches: neurobiology and clinical implications
    Innocenzo Rainero
    Neurology II Headache Centre, Department of Neuroscience, University of Turin, Via Cherasco 15 10126, Torino, Italy
    Expert Rev Neurother 8:409-16. 2008
    ..The aim of this review is to describe and discuss recent studies in humans suggesting a role for the hypocretin neuronal system in cluster headache and chronic migraine...
  4. ncbi request reprint Association between the tumor necrosis factor-alpha -308 G/A gene polymorphism and migraine
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Italy
    Neurology 62:141-3. 2004
    ..30, p < 0.001) but not in migraine with aura. These data suggest that the TNFalpha gene or a linked locus significantly modulates the risk for migraine...
  5. ncbi request reprint Haemochromatosis gene (HFE) polymorphisms and migraine: an association study
    I Rainero
    Neurology II, Headache Centre, Department of Neuroscience, University of Torino, Torino, Italy
    Cephalalgia 27:9-13. 2007
    ..Our data suggest that the HFE gene is not a major disease gene for migraine. However, the H63D polymorphism of the HFE gene may be considered a modifying genetic factor in migraine...
  6. ncbi request reprint Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Via Cherasco, 15 10126 Torino, Italy
    Neurobiol Aging 25:1293-8. 2004
    ..Analysis of subgroups showed a significant association in patients with early-onset AD but not in late-onset AD. Our data support a significant but modest association between the T/T genotype of the IL-1alpha gene and AD...
  7. ncbi request reprint A polymorphism of the hypocretin receptor 2 gene is associated with cluster headache
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Via Cherasco 15 10126 Turin, Italy
    Neurology 63:1286-8. 2004
    ..Homozygosity for the G allele was associated with an increased disease risk (OR: 6.79, 95% CI, 2.25 to 22.99). The data suggest that the HCRTR2 gene or a linked locus significantly modulates the risk for cluster headache...
  8. ncbi request reprint Insulin sensitivity is impaired in patients with migraine
    I Rainero
    Neurology III Headache Centre, Department of Neuroscience, University of Turin, Italy
    Cephalalgia 25:593-7. 2005
    ..Our data show that insulin sensitivity is impaired in migraine and suggest a role for insulin resistance in the comorbidity between migraine and vascular diseases...
  9. ncbi request reprint Lack of association between the 3092 T-->C Clock gene polymorphism and cluster headache
    I Rainero
    Neurology III, Headache Centre, Department of Neuroscience, University of Torino, Torino, Italy
    Cephalalgia 25:1078-81. 2005
    ..In conclusion, our study suggests that the 3092 T-->C polymorphism of the Clock gene is unlikely to play an important role in cluster headache...
  10. ncbi request reprint HLA-DRB1 genotyping in Italian migraine patients
    Innocenzo Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Via Cherasco 15, Torino 10126, Italy
    Neurosci Lett 393:90-3. 2006
    ..Our data suggest the presence of a genetic susceptibility factor for migraine without aura within the HLA region...
  11. pmc Association between migraine and HLA-DRB1 gene polymorphisms
    Innocenzo Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Via Cherasco 15, I 10126, Turin, Italy
    J Headache Pain 6:185-7. 2005
    ..We conclude that, in Italian patients, migraine is associated with different alleles of the HLA-DRB1 locus. Our data suggest the presence of a genetic susceptibility factor for migraine within the HLA region...
  12. ncbi request reprint Absence of linkage between the interleukin-6 gene (-174 G/C) polymorphism and migraine
    Innocenzo Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Via Cherasco 15 10126, Turin, Italy
    Neurosci Lett 343:155-8. 2003
    ..In conclusion, we found no significant association between the -174 G/C IL-6 polymorphism and the occurrence or the clinical features of migraine...
  13. ncbi request reprint Pro-inflammatory cytokine genes influence the clinical features of frontotemporal lobar degeneration
    Innocenzo Rainero
    Neurology II, Department of Neuroscience, University of Turin, IT 10126 Turin, Italy
    Dement Geriatr Cogn Disord 27:543-7. 2009
    ..The objective of this study was to evaluate the association of functionally active polymorphisms in pro-inflammatory cytokine genes with the occurrence and the clinical features of the disease...
  14. ncbi request reprint A comparison of familial and sporadic migraine in a headache clinic population
    Innocenzo Rainero
    Neurology III, Headache Center, Department of Neuroscience, University of Turin, Italy
    Funct Neurol 17:193-7. 2002
    ..01) earlier age at onset of the disease. No significant difference in all the remaining features examined was found. Our data suggest that famM and spoM represent a single disease entity...
  15. pmc Evidence for an association between migraine and the hypocretin receptor 1 gene
    Innocenzo Rainero
    Neurology II, Department of Neuroscience, University of Torino, Via Cherasco 15, 10126 Turin, Italy
    J Headache Pain 12:193-9. 2011
    ..In conclusion, our data supports the hypothesis that the HCRTR1 gene could represent a genetic susceptibility factor for migraine without aura and suggests that the hypocretin system may have a role in the pathophysiology of migraine...
  16. ncbi request reprint Neuroendocrine effects of subcutaneous sumatriptan in patients with migraine
    I Rainero
    Neurology III, Headache Center, Department of Neuroscience, University of Turin, Italy
    J Endocrinol Invest 24:310-4. 2001
    ..The neuroendocrine response was not significantly different in the two groups. Our results suggest that 5-HT1D receptor sensitivity is not altered in migraine...
  17. ncbi request reprint Quantitative EEG responses to ischaemic arm stress in migraine
    I Rainero
    Neurology II Headache Center, Department of Neuroscience, University of Turin Medical School, Torino, Italy
    Cephalalgia 21:224-9. 2001
    ..The results of our study show that migraine sufferers display a lower threshold to physical stress and confirm previous studies indicating that migraine is a disease characterized by a state of altered neuronal excitability...
  18. ncbi request reprint Apolipoprotein E gene polymorphisms in patients with migraine
    Innocenzo Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Via Cherasco 15, 10126 Turin, Italy
    Neurosci Lett 317:111-3. 2002
    ..In conclusion, we observed no significant association between APOE polymorphisms and migraine. The association between the APOE varepsilon2-varepsilon4 genotype and the tension-type headache deserves further evaluation...
  19. pmc Association between the G1246A polymorphism of the hypocretin receptor 2 gene and cluster headache: a meta-analysis
    Innocenzo Rainero
    Neurology II Headache Centre, Department of Neuroscience, University of Turin, Via Cherasco 15, I 10126 Turin, Italy
    J Headache Pain 8:152-6. 2007
    ..75, CI 95% 1.37-2.25; RE OR 1.69, CI 95% 1.11-2.58). Our data confirm that the G1246A polymorphism of the HCRTR2 gene may modulate the genetic risk for CH...
  20. doi request reprint Association between major mood disorders and the hypocretin receptor 1 gene
    Innocenzo Rainero
    Neurology II, Department of Neuroscience, University of Turin, Italy
    J Affect Disord 130:487-91. 2011
    ....
  21. ncbi request reprint Tumor necrosis factor-alpha gene and cerebral aneurysms
    Marco Fontanella
    Department of Neuroscience, Division of Neurosurgery, University of Turin, Turin, Italy
    Neurosurgery 60:668-72; discussion 672-3. 2007
    ..The purpose of this study is to evaluate the association of a functionally active polymorphism (-308 G<A) in the TNF-alpha gene with the risk and the clinical features of aneurysmal subarachnoid hemorrhage...
  22. ncbi request reprint Interleukin-1 cluster gene polymorphisms and aneurysmal subarachnoid hemorrhage
    Marco Fontanella
    Division of Neurosurgery, Department of Neuroscience, University of Torino, Torino, Italy
    Neurosurgery 66:1058-62; discussion 1062-3. 2010
    ..Interleukin (IL)-1 is a proinflammatory cytokine that plays a pivotal role in both acute and chronic central nervous system injuries...
  23. ncbi request reprint Prevalence of HFE (hemochromatosis) gene mutations in patients with cluster headache
    Innocenzo Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Turin, Italy
    Headache 45:1219-23. 2005
    ..To evaluate whether polymorphisms of the HFE gene would modify the occurrence and the clinical features of cluster headache (CH)...
  24. doi request reprint Cluster headache is associated with the alcohol dehydrogenase 4 (ADH4) gene
    Innocenzo Rainero
    Neurology II Headache Center, Department of Neuroscience, University of Torino, Torino, Italy
    Headache 50:92-8. 2010
    ..The purpose of this study was to investigate the association of genetic variants within the ADH4 gene with cluster headache susceptibility and phenotype...
  25. doi request reprint Brain arteriovenous malformations are associated with interleukin-1 cluster gene polymorphisms
    Marco Fontanella
    Division of Neurosurgery, Department of Neuroscience, University of Torino, Torino, Italy
    Neurosurgery 70:12-7. 2012
    ..Functional polymorphisms in proinflammatory cytokines have been associated with various cerebrovascular phenotypes, including ischemic stroke, aneurysmal subarachnoid hemorrhage, and BAVM...
  26. ncbi request reprint A polymorphism in the interleukin-1alpha gene influences the clinical features of migraine
    Innocenzo Rainero
    Neurology III, Headache Center, Department of Neuroscience, University of Torino, Italy
    Headache 42:337-40. 2002
    ..To evaluate whether a particular genotype of the interleukin-1alpha (IL1A) gene affects the clinical features of migraine...
  27. ncbi request reprint Lack of association between the apolipoprotein E gene and aneurysmal subarachnoid hemorrhage in an Italian population
    Marco Fontanella
    Division of Neurosurgery, Department of Neuroscience, University of Turin, Italy
    J Neurosurg 106:245-9. 2007
    ..The purpose of this study was to evaluate whether a particular allele or genotype of the APOE gene would modify the occurrence or the clinical features of SAH...
  28. ncbi request reprint Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective
    Fabrizio Benedetti
    Department of Neuroscience, University of Turin Medical School, Turin, Italy
    Pain 121:133-44. 2006
    ....
  29. doi request reprint Pain perception and tolerance in patients with frontotemporal dementia
    Elisa Carlino
    Department of Neuroscience, University of Turin, Turin, Italy
    Pain 151:783-9. 2010
    ..Our results suggest differences in pain processing changes in distinct types of dementia, while at the same time caution that pain perception assessment may depend on the criteria adopted for diagnosis...
  30. ncbi request reprint Apolipoprotein E polymorphisms in frontotemporal lobar degeneration: a meta-analysis
    Elisa Rubino
    Neurology II, Department of Neuroscience, University of Torino, Torino, Italy Electronic address
    Alzheimers Dement 9:706-13. 2013
    ..The study objective was to define and quantify further the disease risk associated with the carriage of different APOE alleles to determine whether APOE gene polymorphism is a risk factor for FTLD...
  31. doi request reprint Vascular endothelial growth factor gene polymorphisms and intracranial aneurysms
    Marco Fontanella
    Department of Neuroscience, Division of Neurosurgery, University of Turin, Turin, Italy
    Acta Neurochir (Wien) 155:1511-5. 2013
    ....
  32. pmc Genetic variants in the NOTCH4 gene influence the clinical features of migraine
    Elisa Rubino
    Neurology II, Department of Neuroscience, University of Torino, Via Cherasco 15, Torino, 10126, Italy
    J Headache Pain 14:28. 2013
    ..The aim of this study was to test the hypothesis that polymorphisms of the NOTCH4 gene would modify the occurrence and the clinical features of migraine...
  33. doi request reprint Haplotype analysis confirms the association between the HCRTR2 gene and cluster headache
    Innocenzo Rainero
    Neurology II Headache Center, Department of Neuroscience, Turin, Italy
    Headache 48:1108-14. 2008
    ..This association was confirmed in a large study from Germany but was not replicated in a dataset of CH patients from Northern Europe...
  34. doi request reprint Proinflammatory cytokine gene polymorphisms and susceptibility to Paget's disease of bone: an association study
    Salvatore Gallone
    Neurology II, Department of Neuroscience, University of Torino, Italy
    Cytokine 56:560-3. 2011
    ....
  35. ncbi request reprint Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses
    Fabrizio Benedetti
    Department of Neuroscience, University of Turin Medical School, Turin, Italy 10125
    J Neurosci 23:4315-23. 2003
    ....
  36. doi request reprint Absence of TARDBP gene mutations in an italian series of patients with frontotemporal lobar degeneration
    Salvatore Gallone
    Neurology II, Department of Neuroscience, University of Turin, Turin, Italy
    Dement Geriatr Cogn Disord 28:239-43. 2009
    ..The aim of this study was to search for mutations of the TARDBP gene in the disease...
  37. doi request reprint Subarachnoid hemorrhage and negative angiography: clinical course and long-term follow-up
    Marco Fontanella
    Division of Neurosurgery, Department of Neuroscience, University of Torino, Via Cherasco 15, 10126, Torino, Italy
    Neurosurg Rev 34:477-84. 2011
    ..D-SAH is probably due to an aneurysm that thrombose early after the bleeding. At short-term follow-up, the sack could frequently recanalize and rebleed, whereas a late follow-up shows that rebleeding is very rare...
  38. pmc Genes and primary headaches: discovering new potential therapeutic targets
    Innocenzo Rainero
    Headache Center, Neurology I, Department of Neuroscience, University of Torino, Via Cherasco 15, Torino 10126, Italy
    J Headache Pain 14:61. 2013
    ..Involvement of these genes in primary headaches, as well as their potential role in the therapy of these disorders, will be discussed. ..
  39. pmc SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    Elisa Rubino
    Neurology II, Department of Internal Medicine, University of Torino, Torino, Italy
    Neurology 79:1556-62. 2012
    ..The purpose of our study was to evaluate the frequency of SQSTM1 mutations in a dataset of unrelated patients with FTLD or ALS, in comparison with healthy controls and patients with Paget disease of bone (PDB)...
  40. ncbi request reprint Endocrine function is altered in chronic migraine patients with medication-overuse
    Innocenzo Rainero
    Department of Neuroscience, Neurology III Headache Center, University of Turin, Via Cherasco 15, 10126 Torino, Italy
    Headache 46:597-603. 2006
    ..To evaluate the effects of analgesic overuse on endocrine function in patients with chronic migraine and medication-overuse headache (CM-MOH)...
  41. pmc Genetics of cluster headache: an update
    Lorenzo Pinessi
    Neurology III, Headache Center, Department of Neuroscience, University of Turin, Via Cherasco 15, I 10126, Turin, Italy
    J Headache Pain 6:234-6. 2005
    ..Recently, we have reported a significant association between the HCRTR2 gene and the disease. The purpose of this review is to describe recent advances in the genetics of CH...
  42. ncbi request reprint Anger, depression and personality dimensions in patients with migraine without aura
    Giovanni Abbate-Daga
    Psychiatry Section, Department of Neuroscience, Ospedale San Giovanni Battista, Psichiatria Universitaria CPR DCA, Turin, Italy
    Psychother Psychosom 76:122-8. 2007
    ..The aim of this study was to identify whether migraine patients and controls share distinctive personality traits...
  43. doi request reprint Voxel-based morphometry reveals gray matter abnormalities in migraine
    Walter Valfrè
    Neurology II, Headache Center, The Department of Neuroscience, University of Torino, Italy
    Headache 48:109-17. 2008
    ..Migraine is generally considered a functional brain disorder lacking structural abnormalities. Recent magnetic resonance imaging (MRI) studies, however, suggested that migraine may be associated with subtle brain lesions...
  44. ncbi request reprint The 1246G-->A polymorphism of the HCRTR2 gene is not associated with migraine
    L Pinessi
    Neurology II, Headache Centre, Department of Neuroscience, University of Torino, Torino, Italy
    Cephalalgia 27:945-9. 2007
    ..Comparison of the clinical features of the disease with the 1246G-->A genotypes showed no significant difference. Our data suggest that the HCRTR2 gene is not a genetic risk factor in migraine...
  45. ncbi request reprint Resolution of cluster headache after closure of an anterior communicating artery aneurysm: the role of pericarotid sympathetic fibres
    Salvatore Gentile
    Neurology III Headache Centre, Department of Neuroscience, University of Torino, Via Cherasco 15, 10126 Torino, Italy
    Clin Neurol Neurosurg 108:195-8. 2006
    ..We suggest that the surgical dissection of the pericarotid sympathetic fibres could prevent the onset of the cluster headache attacks by cutting part of the circuit underlying it...
  46. ncbi request reprint Pain reactivity in Alzheimer patients with different degrees of cognitive impairment and brain electrical activity deterioration
    Fabrizio Benedetti
    Department of Neuroscience, University of Turin Medical School, Corso Raffaello 30, 10125 Turin, Italy
    Pain 111:22-9. 2004
    ..This sensory-affective dissociation is well correlated with the neuropathological findings in AD...
  47. pmc Cluster headache attacks and multiple sclerosis
    Salvatore Gentile
    Neurology II Headache Centre, Department of Neuroscience, University of Turin, Via Cherasco 15, I 10126, Torino, Italy
    J Headache Pain 8:245-7. 2007
    ..The association between cluster headache and MS has been rarely described before. This case suggests that in patients with cluster headache neuroimaging is often useful in order to exclude structural lesions...
  48. ncbi request reprint Dehydroepiandrosterone sulfate (DHEA-S) and Alzheimer's dementia in older subjects
    Mario Bo
    Section of Geriatrics, Department of Medical and Surgical Disciplines, University of Turin, Torino, Italy
    Int J Geriatr Psychiatry 21:1065-70. 2006
    ..5+/-6.7 years, 46 men) with first-diagnosed probable DAT and in 158 age- and sex-matched controls. As secondary goal, we evaluated whether DHEA-S baseline levels were associated with cumulative 6-year mortality...
  49. pmc Investigating the genetic role of aquaporin4 gene in migraine
    Elisa Rubino
    Neurology II, Department of Neuroscience, University of Turin, Via Cherasco 15, 10126 Turin, Italy
    J Headache Pain 10:111-4. 2009
    ..Our data do not support the hypothesis that the AQP4 gene could represent a genetic susceptibility factor for migraine...
  50. doi request reprint Interleukin 6 gene polymorphisms are not associated with aneurysmal subarachnoid haemorrhage in an Italian population
    M Fontanella
    Division of Neurosurgery, Department of Neuroscience, University of Turin, Via Cherasco 15 10126 Torino, Italy
    J Neurol Neurosurg Psychiatry 79:471-3. 2008
    ....
  51. ncbi request reprint Headache attributed to spontaneous low CSF pressure: report of three cases responsive to corticosteroids
    S Gentile
    Neurology III Headache Center, Department of Neuroscience, University of Torino, Torino, Italy
    Eur J Neurol 11:849-51. 2004
    ..We report three patients with headache attributed to spontaneous low CSF pressure that were successfully treated with oral prednisone. Additional studies may be useful to prove the effectiveness of corticosteroids in this syndrome...
  52. ncbi request reprint Food and headache attacks. A comparison of patients with migraine and tension-type headache
    L Savi
    Neurology III, Headache Center, Department of Neuroscience, University of Turin, Turin, Italy
    Panminerva Med 44:27-31. 2002
    ..Some authors reported that also tension type headache attacks may be provoked by foods. The purpose of this study was to evaluate the role of foods as headache triggers in both groups of patients...
  53. doi request reprint Reversible MRI abnormalities in a patient with recurrent status migrainosus
    S Gentile
    Neurology II Headache Centre, Department of Neuroscience, University of Turin, Via Cherasco 15 10126 Torino, Italy
    Cephalalgia 29:687-90. 2009
    ..These abnormalities, confirmed also by positron emission tomography, suggest that status migrainosus can be associated with a condition of vasogenic cerebral oedema...
  54. ncbi request reprint Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis
    E Rubino
    Neurology II, Headache Centre, Department of Neuroscience, University of Torino, Torino, Italy
    Cephalalgia 29:818-25. 2009
    ..32, 95% CI 1.10, 1.59; RE OR 1.63, 95% CI 1.10, 2.43). This study provides evidence for an association of the MTHFR gene only in migraine with aura...
  55. ncbi request reprint Decreased sensitivity of 5-HT1D receptors in chronic tension-type headache
    I Rainero
    Neurology III Headache Center, Department of Neuroscience, University of Turin, Italy
    Headache 42:709-14. 2002
    ..To assess the sensitivity of 5-HT1D receptors in chronic tension-type headache using sumatriptan as a pharmacological probe...
  56. ncbi request reprint Placebo analgesia and the heart
    Antonella Pollo
    Department of Neuroscience, University of Turin Medical School, Corso Raffaello 30, 10125 Turin, Italy
    Pain 102:125-33. 2003
    ..15 Hz) spectral component was reduced during placebo analgesia, an effect that was reversed by naloxone. These findings indicate that placebo analgesia is accompanied by a complex cascade of events which affect the cardiovascular system...
  57. ncbi request reprint Effects of subcutaneous sumatriptan on plasma growth hormone concentrations in migraine patients
    L Pinessi
    Neurology III Headache Centre, Department of Neuroscience, University of Turin, Italy
    Cephalalgia 20:223-7. 2000
    ..Our results suggest that cerebral serotonergic functions mediated by 5-HT1D receptors are not altered in migraine. Sumatriptan overuse could lead to adverse effects mediated by its neuroendocrine activity...
  58. ncbi request reprint Pain threshold and tolerance in Alzheimer's disease
    F Benedetti
    Department of Neuroscience, CIND Center for the Neurophysiology of Pain, University of Torino Medical School, Italy
    Pain 80:377-82. 1999
    ..Thus, pain tolerance is tightly related to the severity of the disease according to the rule, 'the more severe the MMSE and EEG changes, the higher the tolerance to pain'...
  59. ncbi request reprint Chronic Helicobacter pylori infection and migraine: a case-control study
    L Pinessi
    Neurology III-Headache Center, Department of Neuroscience, University of Turin, Italy
    Headache 40:836-9. 2000
    ..CONCLUSIONS: Our study suggests that chronic Helicobacter pylori infection is not more frequent in patients with migraine than in controls and that infection does not modify clinical features of the disease...
  60. ncbi request reprint Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with sumatriptan
    L Pinessi
    Neurology III, Headache Centre, Department of Neuroscience, Division of Endocrinology, Department of Internal Medicine and Division of Medicine, Department of Internal Medicine, University of Turin, Turin, Italy
    Cephalalgia 23:354-60. 2003
    ..05) reduced in patients with cluster headache, both in the active and in the remission period. Our results suggest that cerebral serotonergic functions mediated by 5-HT(1D) receptors are altered in patients with episodic cluster headache...
  61. ncbi request reprint Lack of interaction between a polymorphism in the dopamine D2 receptor gene and the clinical features of migraine
    N Rebaudengo
    Neurology Service, Gradenigo Hospital, Turin, Italy
    Cephalalgia 24:503-7. 2004
    ..The results of our study do not support a role for the DRD2 gene in modifying the clinical features of migraine...
  62. pmc The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
    Ekaterina Rogaeva
    Centre for Research in Neurodegenerative Diseases, Department of Medicine, Department, University of Toronto, Toronto, Ontario, Canada
    Nat Genet 39:168-77. 2007
    ..These data suggest that inherited or acquired changes in SORL1 expression or function are mechanistically involved in causing Alzheimer disease...
  63. ncbi request reprint Migraine headache and mood disorders: a descriptive study in an outpatient psychiatric population
    Linda Franchini
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Sciences, School of Medicine, Universita Vita e Salute, Via Stamira d Ancona 20, 20127 Milan, Italy
    J Affect Disord 81:157-60. 2004
    ..Information is sparse concerning migraine distribution in mood disorder subjects based mainly on psychiatric disorder...