Francesco Puoci

Summary

Affiliation: University of Calabria
Country: Italy

Publications

  1. ncbi request reprint Synthesis and antioxidant efficiency of a new copolymer containing phosphorylated myo-inositol
    Francesca Iemma
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, 87036 Rende CS, Italy
    Macromol Biosci 5:1049-56. 2005
  2. ncbi request reprint Molecularly imprinted polymers for 5-fluorouracil release in biological fluids
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italy
    Molecules 12:805-14. 2007
  3. ncbi request reprint Anticancer activity of a quercetin-based polymer towards HeLa cancer cells
    Francesco Puoci
    Department of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende CS, 87036, Italy
    Anticancer Res 32:2843-7. 2012
  4. pmc Antioxidant activity of a Mediterranean food product: "fig syrup"
    Francesco Puoci
    Pharmaceutical Sciences Department, University of Calabria, Edificio Polifunzionale, Arcavacata di Rende 87036, Italy
    Nutrients 3:317-29. 2011
  5. ncbi request reprint Spherical molecularly imprinted polymers (SMIPs) via a novel precipitation polymerization in the controlled delivery of sulfasalazine
    F Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, 87036 Arcavacata di Rende CS, Italy
    Macromol Biosci 4:22-6. 2004
  6. doi request reprint Molecularly imprinted polymers in drug delivery: state of art and future perspectives
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Cosenza, Italy
    Expert Opin Drug Deliv 8:1379-93. 2011
  7. doi request reprint Synthesis of methacrylic-ferulic acid copolymer with antioxidant properties by single-step free radical polymerization
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende, CS, Italia
    J Agric Food Chem 56:10646-50. 2008
  8. ncbi request reprint Molecularly imprinted polymers for alpha-tocopherol delivery
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Arcavacata di Rende, Italy
    Drug Deliv 15:253-8. 2008
  9. ncbi request reprint Stimuli-responsive molecularly imprinted polymers for drug delivery: a review
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS, Italy
    Curr Drug Deliv 5:85-96. 2008
  10. ncbi request reprint Molecularly imprinted solid phase extraction for the selective HPLC determination of alpha-tocopherol in bay leaves
    F Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italy
    Anal Chim Acta 593:164-70. 2007

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Synthesis and antioxidant efficiency of a new copolymer containing phosphorylated myo-inositol
    Francesca Iemma
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, 87036 Rende CS, Italy
    Macromol Biosci 5:1049-56. 2005
    ..Finally, we evaluated the copolymer's ability in inhibiting lipid peroxidation in rat liver microsomal membranes. This study showed that the designed macromolecular system is particularly effective as antioxidant...
  2. ncbi request reprint Molecularly imprinted polymers for 5-fluorouracil release in biological fluids
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italy
    Molecules 12:805-14. 2007
    ....
  3. ncbi request reprint Anticancer activity of a quercetin-based polymer towards HeLa cancer cells
    Francesco Puoci
    Department of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende CS, 87036, Italy
    Anticancer Res 32:2843-7. 2012
    ..g. body fluids) has so far hampered its introduction into clinical practice. Aim: To overcome this inconvenience, quercetin was covalently conjugated into a polymethacrylic acid backbone and the conjugate was tested on HeLa cancer cells...
  4. pmc Antioxidant activity of a Mediterranean food product: "fig syrup"
    Francesco Puoci
    Pharmaceutical Sciences Department, University of Calabria, Edificio Polifunzionale, Arcavacata di Rende 87036, Italy
    Nutrients 3:317-29. 2011
    ....
  5. ncbi request reprint Spherical molecularly imprinted polymers (SMIPs) via a novel precipitation polymerization in the controlled delivery of sulfasalazine
    F Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, 87036 Arcavacata di Rende CS, Italy
    Macromol Biosci 4:22-6. 2004
    ..This opens the possibility of the development of drug release systems capable of modulating the release of a specific molecule. Photomicrography of spherical molecularly imprinted polymers (SMIPs)...
  6. doi request reprint Molecularly imprinted polymers in drug delivery: state of art and future perspectives
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Cosenza, Italy
    Expert Opin Drug Deliv 8:1379-93. 2011
    ....
  7. doi request reprint Synthesis of methacrylic-ferulic acid copolymer with antioxidant properties by single-step free radical polymerization
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende, CS, Italia
    J Agric Food Chem 56:10646-50. 2008
    ..Good antioxidant activity was demonstrated by obtained materials, showing the efficiency of the polymerization method. This material could be useful in the pharmaceutical field and in the food industry (food packaging)...
  8. ncbi request reprint Molecularly imprinted polymers for alpha-tocopherol delivery
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Arcavacata di Rende, Italy
    Drug Deliv 15:253-8. 2008
    ..Imprinted polymers bound much more alpha-tocopherol and showed a controlled/sustained drug release capacity in gastrointestinal simulating fluids...
  9. ncbi request reprint Stimuli-responsive molecularly imprinted polymers for drug delivery: a review
    Francesco Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS, Italy
    Curr Drug Deliv 5:85-96. 2008
    ..The "stimuli-responsive molecularly imprinted polymers" reviewed in this paper are expected to contribute significantly to the exploration and development of new generations of intelligent and self-regulated drug delivery systems...
  10. ncbi request reprint Molecularly imprinted solid phase extraction for the selective HPLC determination of alpha-tocopherol in bay leaves
    F Puoci
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italy
    Anal Chim Acta 593:164-70. 2007
    ..16x10(-6) mol L(-1), respectively, as well as good precision (intraday precision below 3.3% and interday precisions below 6.5%) and recovery (60%). Thus, it can be successfully used for the purification of alpha-TP from bay leaves...
  11. doi request reprint Grafted thermo-responsive gelatin microspheres as delivery systems in triggered drug release
    Manuela Curcio
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Arcavacata di Rende CS, Italy
    Eur J Pharm Biopharm 76:48-55. 2010
    ..By using semi-empirical equations, the release mechanism was extensively studied and the diffusional contribution was evaluated...
  12. doi request reprint Flavonoids preservation and release by methacrylic acid-grafted (N-vinyl-pyrrolidone)
    Ortensia Ilaria Parisi
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende, Italy
    Pharm Dev Technol 18:1058-65. 2013
    ..Flavonoids preservation and release...
  13. doi request reprint Preparation, characterization and efficacy evaluation of synthetic biocompatible polymers linking natural antioxidants
    Sonia Trombino
    Department of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende 87036, Cosenza, Italy
    Molecules 17:12734-45. 2012
    ..Moreover, the cytotoxicity of the synthesized polymers was also evaluated on Caco-2 cell cultures in order to verify their biocompatibility when exposed to an absorptive epithelial cell line...
  14. doi request reprint Starch-quercetin conjugate by radical grafting: synthesis and biological characterization
    Giuseppe Cirillo
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italia
    Pharm Dev Technol 17:466-76. 2012
    ..The conjugate also prevented drug degradation and shows potential health functionality in the treatment of Alzheimer disease, diabetes and as skin-whitening agent...
  15. doi request reprint Temperature-sensitive hydrogels by graft polymerization of chitosan and N-isopropylacrylamide for drug release
    Umile Gianfranco Spizzirri
    Department of Pharmaceutical Sciences, University of Calabria, Edificio Polifunzionale, Rende CS, Italy
    Pharm Dev Technol 18:1026-34. 2013
    ....
  16. doi request reprint Antioxidant multi-walled carbon nanotubes by free radical grafting of gallic acid: new materials for biomedical applications
    Giuseppe Cirillo
    Department of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende CS, Italy
    J Pharm Pharmacol 63:179-88. 2011
    ....
  17. doi request reprint Gastro-intestinal sustained release of phytic acid by molecularly imprinted microparticles
    Giuseppe Cirillo
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italia
    Pharm Dev Technol 15:526-31. 2010
    ....
  18. ncbi request reprint Design and synthesis of cellulose derivatives with antioxidant activity
    Sonia Trombino
    Department of Pharmaceutical Sciences, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
    Macromol Biosci 8:86-95. 2008
    ..Moreover, the cellulose ferulate with the higher degree of substitution acted as the best antioxidant...
  19. doi request reprint Synthesis of stimuli-responsive microgels for in vitro release of diclofenac diethyl ammonium
    Giuseppe Cirillo
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Rende CS 87036, Italia
    J Biomater Sci Polym Ed 22:823-44. 2011
    ..The data recorded during the release tests demonstrated that the pH of the surrounding environment influences the drug release more than the temperature of the imbibing medium...
  20. pmc Negative thermo-responsive microspheres based on hydrolyzed gelatin as drug delivery device
    Manuela Curcio
    Pharmaceutical Science Department, University of Calabria, Edificio Polifunzionale, Rende, CS, Italy
    AAPS PharmSciTech 11:652-62. 2010
    ..The physico-chemical characteristics of thermo-responsive materials confirm the applicability of the microspheres as drug delivery device...
  21. doi request reprint Molecularly imprinted polymers as drug delivery systems for the sustained release of glycyrrhizic acid
    Giuseppe Cirillo
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Arcavacata di Rende CS, Italy
    J Pharm Pharmacol 62:577-82. 2010
    ....
  22. doi request reprint Covalent insertion of antioxidant molecules on chitosan by a free radical grafting procedure
    Manuela Curcio
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende, CS 87036, Italy
    J Agric Food Chem 57:5933-8. 2009
    ..The good antioxidant activity shown by functionalized materials proved the efficiency of the reaction method...
  23. ncbi request reprint Iron (III) chelation and antioxidant properties of myo-inositol phosphorylated polymeric microspheres
    Francesca Iemma
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, 87036 Rende CS, Italy
    J Pharm Pharmacol 59:597-601. 2007
    ....
  24. doi request reprint Synthesis of antioxidant polymers by grafting of gallic acid and catechin on gelatin
    Umile Gianfranco Spizzirri
    Dipartimento di Scienze Farmaceutiche, Università della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italia
    Biomacromolecules 10:1923-30. 2009
    ..The results clearly showed that antioxidant moieties covalently bounded to a natural polymer allow to introduce in the macromolecule peculiar features for specific industrial applications...
  25. doi request reprint Quercetin nanocomposite as novel anticancer therapeutic: improved efficiency and reduced toxicity
    Giuseppe Cirillo
    Department of Pharmacy, Health and Nutrition Sciences, University of Calabria, I 87036 Arcavacata di Rende CS, Italy
    Eur J Pharm Sci 49:359-65. 2013
    ..Cell viability tests on healthy cells demonstrated no-toxicity of the conjugate...
  26. ncbi request reprint pH-sensitive hydrogels based on bovine serum albumin for oral drug delivery
    Francesca Iemma
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, 87036 Rende CS, Italy
    Int J Pharm 312:151-7. 2006
    ..8 was observed. In the case of diflunisal pH-sensitive release was observed. At pH 1.0 low amounts of drug were released (w/w<10% after 2 h). When the pH is 6.8, the diflunisal release increased in the amount (w/w>75% after 24 h)...
  27. doi request reprint Biological activity of a gallic acid-gelatin conjugate
    Giuseppe Cirillo
    Dipartimento di Scienze Farmaceutiche, Università della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italia
    Biomacromolecules 11:3309-15. 2010
    ..Finally, the anticancer activity of Gel-GA was proven in prostate carcinoma and renal cell carcinoma cell lines, confirming the potential of the proposed protein-polyphenol conjugate in medicine...
  28. doi request reprint A new method for the determination of biogenic amines in cheese by LC with evaporative light scattering detector
    Donatella Restuccia
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende CS 87036, Italy
    Talanta 85:363-9. 2011
    ..This value does not represent a possible risk for consumer health, according to the toxicity levels reported in literature and regarded as acceptable...
  29. doi request reprint Selective determination of melamine in aqueous medium by molecularly imprinted solid phase extraction
    Manuela Curcio
    Dipartimento di Scienze Farmaceutiche, Edificio Polifunzionale, Università della Calabria, Arcavacata di Rende CS 87036, Italy
    J Agric Food Chem 58:11883-7. 2010
    ..Finally, the ability of MIP to selectively extract melamine from two real samples, a food supplement and a freeze-dried meat sample, was demonstrated...
  30. doi request reprint Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: a review of in vitro studies
    Ivan Casaburi
    Department of Pharmaco Biology and Pharmaceutical Sciences, University of Calabria, Cosenza, Italy
    Mol Nutr Food Res 57:71-83. 2013
    ....
  31. ncbi request reprint Imprinted hydrophilic nanospheres as drug delivery systems for 5-fluorouracil sustained release
    G Cirillo
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Edificio Polifunzionale, Arcavacata di Rende, Italy
    J Drug Target 17:72-7. 2009
    ..Finally, in vitro release studies were performed in plasma simulating fluids...
  32. doi request reprint Synthesis, characterization and antimicrobial activity of conjugates based on fluoroquinolon-type antibiotics and gelatin
    Giuseppe Cirillo
    Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Edificio Polifunzionale, 87036, Rende, CS, Italy
    J Mater Sci Mater Med 25:67-77. 2014
    ..The collected data suggest a broad range of applications, from biomedical to pharmaceutical and food science for all conjugates. ..
  33. doi request reprint A new member of the oxygen-photosensitizers family: a water-soluble polymer binding a platinum complex
    Loredana Ricciardi
    Department of Chemistry, University of Calabria, I 87036 Rende CS, Italy
    Dalton Trans 41:10923-5. 2012
    ..The obtained polymer is water soluble, and it represents the first example of a platinum-containing polymer able to photogenerate singlet oxygen...
  34. ncbi request reprint Silica-based mesoporous materials as drug delivery system for methotrexate release
    Ida Stefania Carino
    Dipartimento di Ingegneria Chimica e dei Materiali, Universita della Calabria, Rende, Italia
    Drug Deliv 14:491-5. 2007
    ..Only alumina-silica samples were able to load methotrexate. The amounts of drug loaded and the in vitro release kinetics are a function of the pore size of the materials...
  35. ncbi request reprint Preparation and characterization of bolaform surfactant vesicles
    Rita Muzzalupo
    Department of Pharmaceutical Science, Calabria University, Ponte P Bucci, Ed Polifunzionale, 87030 Rende, Italy
    Colloids Surf B Biointerfaces 46:78-83. 2005
    ..The results obtained in this study show a high encapsulation capacity and this ability and the size depends on cholesterol content...
  36. ncbi request reprint Radical cross-linked albumin microspheres as potential drug delivery systems: preparation and in vitro studies
    F Iemma
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Rende, Italy
    Drug Deliv 12:229-34. 2005
    ..We considered on the interaction drug-matrix, the fuctionalization degree of albumin, and the water affinity of matrix...
  37. ncbi request reprint Radical crosslinked albumin microspheres as potential drug delivery systems: preparation and in vitro studies
    F Iemma
    Dipartimento di Scienze Farmaceutiche, Universita della Calabria, Rende CS, Italy
    Drug Deliv 12:179-84. 2005
    ..Finally the release profile took into consideration the interaction drug-matrix, the fuctionalization degree of albumin, and the water affinity of matrix...
  38. doi request reprint Enhanced cellular uptake by "pharmaceutically oriented devices" of new simplified analogs of Linezolid with antimicrobial activity
    Ortensia Ilaria Parisi
    Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende CS, Italy Department of Computer Engineering, Modeling, Electronics and Systems, University of Calabria, 87036 Rende CS, Italy
    Int J Pharm 461:163-70. 2014
    ..The incorporation into suitable vehicles, indeed, reduced by 4 times the normal MICs of the newly synthesized oxazolilidin-2-ones and represents an effective strategy to overcome cellular penetration constraints. ..
  39. doi request reprint Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines
    Adele Chimento
    Department of Pharmacy, Health and Nutrition Sciences, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
    Bioorg Med Chem Lett 23:6401-5. 2013
    ..Our results indicate that some azetidin-based resveratrol derivatives may become new potent alternative tools for the treatment of human breast cancer. ..
  40. doi request reprint Olive oil/policosanol organogels for nutraceutical and drug delivery purposes
    Francesca R Lupi
    Department of Information, Modeling, Electronic and System Engineering D I M E S, University of Calabria, Via P Bucci Cubo 39C, I 87036 Rende CS, Italy
    Food Funct 4:1512-20. 2013
    ..This evidenced a release mechanism determined by both erosion and diffusion; a good performance of gels and their ability to control the release rate through the degree of structuration were also observed. ..
  41. doi request reprint Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation
    Rosa Sirianni
    Department of Pharmaco Biology, University of Calabria, Arcavacata di Rende CS, Italy
    Mol Nutr Food Res 54:833-40. 2010
    ..Our study demonstrated that HT and OL can have a chemo-preventive role in breast cancer cell proliferation through the inhibition of estrogen-dependent rapid signals involved in uncontrolled tumor cell growth...