Leonardo Punzi

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi Erosive osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Best Pract Res Clin Rheumatol 18:739-58. 2004
  2. ncbi Epithelial CXCR3-B regulates chemokines bioavailability in normal, but not in Sjogren's syndrome, salivary glands
    Paolo Sfriso
    Department of Clinical and Experimental Medicine, Section of Rheumatology, Centro di Eccellenza per la Ricerca Biomedica, Padova, Italy
    J Immunol 176:2581-9. 2006
  3. ncbi Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial
    Franco Cozzi
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 74:436-9. 2007
  4. doi Methods used to assess remission and low disease activity in rheumatoid arthritis
    Francesca Ometto
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, 35128 Padova, Italy
    Autoimmun Rev 9:161-4. 2010
  5. ncbi [TNFalpha blockers and infectious risk in rheumatoid arthritis]
    B Raffeiner
    Cattedra e U O C di Reumatologia, Dipartimento Medicina Clinica e Sperimentale, Universita di Padova, Italia
    Reumatismo 61:165-73. 2009
  6. pmc Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, University of Padova Padova, Italy
    Front Pharmacol 4:51. 2013
  7. doi Efficacy and safety of certolizumab pegol in rheumatoid arthritis: meeting rheumatologists' requirements in routine clinical practice
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, 35128, Padua, Italy
    BioDrugs 28:25-37. 2014
  8. doi Serum uric acid and gout: from the past to molecular biology
    L Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy
    Curr Med Res Opin 29:3-8. 2013
  9. doi Gout as autoinflammatory disease: new mechanisms for more appropriated treatment targets
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Autoimmun Rev 12:66-71. 2012
  10. doi Coll2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands
    L Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Osteoarthritis Cartilage 20:557-61. 2012

Detail Information

Publications125 found, 100 shown here

  1. ncbi Erosive osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Best Pract Res Clin Rheumatol 18:739-58. 2004
    ..No definitive therapeutic approach to EOA has been reported. It is reasonable to assume that in the presence of a symptomatic EOA our therapeutic approach should differ from that used for common, nodal, non-EOA...
  2. ncbi Epithelial CXCR3-B regulates chemokines bioavailability in normal, but not in Sjogren's syndrome, salivary glands
    Paolo Sfriso
    Department of Clinical and Experimental Medicine, Section of Rheumatology, Centro di Eccellenza per la Ricerca Biomedica, Padova, Italy
    J Immunol 176:2581-9. 2006
    ..They also support a critical role for CXCR3 in the pathogenesis of SS and identify its agonists as potential therapeutic targets...
  3. ncbi Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial
    Franco Cozzi
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 74:436-9. 2007
    ..The objective of this study was to evaluate the effects and the tolerability of mud packs and thermal baths in a group of patients affected with this disease...
  4. doi Methods used to assess remission and low disease activity in rheumatoid arthritis
    Francesca Ometto
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, 35128 Padova, Italy
    Autoimmun Rev 9:161-4. 2010
    ..Thus, those reported by FDA are the only criteria for remission which consider radiographic arrest of the disease. This review aims to describe the criteria for RA remission and to discuss their advantages and limitations...
  5. ncbi [TNFalpha blockers and infectious risk in rheumatoid arthritis]
    B Raffeiner
    Cattedra e U O C di Reumatologia, Dipartimento Medicina Clinica e Sperimentale, Universita di Padova, Italia
    Reumatismo 61:165-73. 2009
    ..Physicians should carefully monitor for signs of infection when using TNF alpha blockers, particularly shortly after treatment initiation...
  6. pmc Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, University of Padova Padova, Italy
    Front Pharmacol 4:51. 2013
    ....
  7. doi Efficacy and safety of certolizumab pegol in rheumatoid arthritis: meeting rheumatologists' requirements in routine clinical practice
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, 35128, Padua, Italy
    BioDrugs 28:25-37. 2014
    ..Current data suggest that certolizumab pegol suits a 'treat to target' approach, providing rapid and sustained improvements in RA signs and symptoms, and beneficial effects on workplace and home productivity in patients with RA. ..
  8. doi Serum uric acid and gout: from the past to molecular biology
    L Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy
    Curr Med Res Opin 29:3-8. 2013
    ..This review will briefly present the epidemiology and risk factors of gout, with a focus on recent advances...
  9. doi Gout as autoinflammatory disease: new mechanisms for more appropriated treatment targets
    Leonardo Punzi
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Autoimmun Rev 12:66-71. 2012
    ..All these aspects, leading to deeper insight, have suggested new treatments, some of which are already available while others are likely to become available in the near future...
  10. doi Coll2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands
    L Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Osteoarthritis Cartilage 20:557-61. 2012
    ....
  11. doi Psoriatic arthritis. When the heterogeneity requires normality
    L Punzi
    University of Padova
    Reumatismo 64:59-65. 2012
    ..This seems obtained with a convenient cost-effectiveness ratio...
  12. doi Miscellaneous non-inflammatory musculoskeletal conditions. Blau syndrome
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
    Best Pract Res Clin Rheumatol 25:703-14. 2011
    ..This review will focus on the clinical and genetics aspects of the familial and the sporadic form of BS. Further, we will describe an Italian family followed by us over the past 25 years...
  13. doi Metabolism of crystals within the joint
    F Oliviero
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Reumatismo 63:221-9. 2011
    ..We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation...
  14. ncbi [Italian consensus on Eular 2003 recommendations for the treatment of knee osteoarthritis]
    L Punzi
    Cattedra ed UOC di Reumatologia, Universita di Padova, Padova
    Reumatismo 56:190-201. 2004
    ..Furthermore, the final document of the Italian Consensus clearly indicated the need that specialists involved in the management of knee OA strongly encourage the dissemination of the EULAR 2003 recommendations also in Italy...
  15. ncbi Laboratory findings in osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Semin Arthritis Rheum 34:58-61. 2005
  16. ncbi New biochemical insights into the pathogenesis of osteoarthritis and the role of laboratory investigations in clinical assessment
    Leonardo Punzi
    Division of Rheumatology, University of Padova, Italy
    Crit Rev Clin Lab Sci 42:279-309. 2005
    ....
  17. ncbi Chronic autoimmune thyroiditis and rheumatic manifestations
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    Joint Bone Spine 71:275-83. 2004
    ....
  18. ncbi Laboratory investigations in osteoarthritis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Aging Clin Exp Res 15:373-9. 2003
    ....
  19. pmc Value of C reactive protein in the assessment of erosive osteoarthritis of the hand
    L Punzi
    Cattedra e Divisione di Reumatologia, Universita di Padova, Via Giustiniani, 235128 Padua, Italy
    Ann Rheum Dis 64:955-7. 2005
    ..To investigate the value of serum C reactive protein (CRP) as a marker of erosive osteoarthritis (EOA) of the hand...
  20. ncbi [Italian consensus on EULAR recommendations 2005 for the management of hip osteoarthritis]
    L Punzi
    Cattedra ed Unità Operativa di Reumatologia, Universita di Padova, Italia
    Reumatismo 58:301-9. 2006
    ..Furthermore, the final document of the Italian Consensus clearly indicated the need that the specialists involved in the management of hip OA strongly encourage the dissemination of the EULAR 2005 recommendations also in Italy...
  21. pmc Serum human cartilage glycoprotein 39 as a marker of arthritis associated with inflammatory bowel disease
    L Punzi
    Division of Rheumatology, University of Padova, Italy
    Ann Rheum Dis 62:1224-6. 2003
    ..Common blood markers of arthritis are difficult to interpret in arthritis associated with inflammatory bowel disease (IBD) owing to the coexistence of two inflammatory events. No specific serological disease marker is available for IBD...
  22. ncbi Inflammatory osteoarthritis of the hand
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Best Pract Res Clin Rheumatol 24:301-12. 2010
    ..Thus, it is probably preferable to use the double term inflammatory/erosive to better define this particular subset of HOA...
  23. doi New horizons in osteoarthritis
    F Oliviero
    Department of Clinical and Experimental Rheumatology, University of Padova, Via Giustiniani, Padova, IT
    Swiss Med Wkly 140:w13098. 2010
    ..Numerous new substances have been formulated and the findings of trials studying their effects are encouraging, although much has yet to be done...
  24. ncbi Clinical significance of cytokine determination in synovial fluid
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
    Crit Rev Clin Lab Sci 39:63-88. 2002
    ..Furthermore, as some of these cytokines may reflect disease activity, their determination may also be useful in the evaluation of therapy...
  25. ncbi Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditis
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Semin Arthritis Rheum 32:51-5. 2002
    ..Our study aims to characterize arthralgia and, in particular, polyarthralgia (PA) associated with CLT and to evaluate the influence of thyroid replacement therapy...
  26. ncbi Arthrocentesis and synovial fluid analysis in clinical practice: value of sonography in difficult cases
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
    Ann N Y Acad Sci 1154:152-8. 2009
    ..Furthermore, ultrasonography may be useful in revealing the presence of synovial fluid before the joint aspiration and, subsequently, distinguishing some aspects characteristic of crystal-induced arthropathies...
  27. doi Clinical and genetic aspects of Blau syndrome: a 25-year follow-up of one family and a literature review
    Leonardo Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Autoimmun Rev 8:228-32. 2009
    ..As in Crohn's disease, CARD15/NOD2 mutation is believed to be responsible for the granulomatous autoinflammatory reactions probably triggered by microorganisms in BS...
  28. ncbi [Italian Society of Rheumatology (SIR) recommendations for performing arthrocentesis]
    L Punzi
    Cattedra ed UOC Reumatologia, Universita di Padova, Italia
    Reumatismo 59:227-34. 2007
    ..Several of these recommendations were based on experts' opinion rather than on published evidence which is scanty...
  29. ncbi Laboratory findings in psoriatic arthritis
    L Punzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Reumatismo 59:52-5. 2007
    ....
  30. ncbi Pathogenetic and clinical rationale for TNF-blocking therapy in psoriatic arthritis
    Leonardo Punzi
    Rheumatology Unit, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Autoimmun Rev 6:524-8. 2007
    ..In this new fashion, the most stimulating hypotheses involving TNF are those regarding genetic predisposition, angiogenesis and osteoclastogenesis...
  31. doi Blockade of intra-articular TNF in peripheral spondyloarthritis: its relevance to clinical scores, quantitative imaging and synovial fluid and synovial tissue biomarkers
    Ugo Fiocco
    Department of Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Joint Bone Spine 80:165-70. 2013
    ....
  32. doi Prevalence of calcium pyrophosphate and monosodium urate crystals in synovial fluid of patients with previously diagnosed joint diseases
    Francesca Oliviero
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Joint Bone Spine 80:287-90. 2013
    ..The main aim of this study was to investigate the frequency of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid (SF) obtained from patients with previously diagnosed joint diseases...
  33. doi The effects of combined spa therapy and rehabilitation on patients with ankylosing spondylitis being treated with TNF inhibitors
    Luca Ciprian
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Rheumatol Int 33:241-5. 2013
    ..Combined spa therapy and rehabilitation caused a clear, long-term clinical improvement in AS patients being treated with TNF inhibitors. Thermal treatment was found to be well tolerated and none of the patients had disease relapse...
  34. ncbi Disease activity patterns in a monocentric cohort of SLE patients: a seven-year follow-up study
    Margherita Zen
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Clin Exp Rheumatol 30:856-63. 2012
    ..To evaluate disease activity patterns and flare occurrence in a cohort of systemic lupus erythematosus (SLE) patients...
  35. doi Synovial biomarkers in psoriatic arthritis
    Ugo Fiocco
    Department of Medicine, University of Padua, Padua, Italy
    J Rheumatol Suppl 89:61-4. 2012
    ..5 mg)...
  36. doi Elderly onset of primary Sjögren's syndrome: clinical manifestations, serological features and oral/ocular diagnostic tests. Comparison with adult and young onset of the disease in a cohort of 336 Italian patients
    Costantino Botsios
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 78:171-4. 2011
    ..To study and compare the clinical and serological features of patients with elderly versus adult and younger onset of primary Sjögren's syndrome (pSS)...
  37. doi Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phase
    Anna Scanu
    Rheumatology Unit, Department of Medicine, University of Padova, Italy
    Ann Rheum Dis 71:621-4. 2012
    ..To determine the most relevant parameters in synovial fluid (SF) during the various stages of acute gout...
  38. doi Rituximab in refractory idiopathic inflammatory myopathies and antisynthetase syndrome: personal experience and review of the literature
    Linda Nalotto
    Division of Rheumatology, Department of Medicine, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy
    Immunol Res 56:362-70. 2013
    ..A significant improvement was observed in 80% of patients overall and the drug was well tolerated in the majority of cases. In conclusion, RTX can be considered a therapeutic option in refractory IIM...
  39. doi Serological markers in psoriatic arthritis: promising tools
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, 35128 Padova, Italy
    Exp Biol Med (Maywood) 238:1431-6. 2013
    ..The rise in PTX3 did not appear to be linked to the inflammatory state of the disease but might be an expression of the atherosclerotic process frequently observed in PsA. ..
  40. doi Treatment of 139 pregnancies in antiphospholipid-positive women not fulfilling criteria for antiphospholipid syndrome: a retrospective study
    Teresa Del Ross
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padua, Italy
    J Rheumatol 40:425-9. 2013
    ..The effect of low-dose aspirin (LDA) on pregnancy outcome in antiphospholipid (aPL)-positive women not fulfilling the criteria for antiphospholipid antibody syndrome (APS) was evaluated retrospectively...
  41. ncbi Emerging and critical issues in the pathogenesis of lupus
    Mariele Gatto
    Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Autoimmun Rev 12:523-36. 2013
    ..e. genetic predisposition, B and T cell abnormalities, abnormal autoantigen availability, autoantibody generation and organ damage, relying on current knowledge and recent insights into SLE development...
  42. doi Overlap connective tissue disease syndromes
    Luca Iaccarino
    Division of Rheumatology, Department of Medicine, University of Padua, Italy
    Autoimmun Rev 12:363-73. 2013
    ..In this paper the most frequent OS are described with a special focus on the specific immunologic and clinical aspects. Furthermore, some personal data on anti-t-RNA synthetase syndrome and rhupus syndrome are reported...
  43. pmc Synovial effusion and synovial fluid biomarkers in psoriatic arthritis to assess intraarticular tumor necrosis factor-α blockade in the knee joint
    Ugo Fiocco
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Arthritis Res Ther 12:R148. 2010
    ....
  44. pmc Effect of pregnancy on serum cytokines in SLE patients
    Andrea Doria
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, 35128, Italy
    Arthritis Res Ther 14:R66. 2012
    ..The aim of this study was to evaluate an extensive panel of cytokines involved in immune regulation during pregnancy in patients with systemic lupus erythematosus (SLE) and in healthy women...
  45. doi Serological markers of erosive hand osteoarthritis
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
    Eur J Intern Med 24:11-5. 2013
    ....
  46. ncbi Optimizing outcome in SLE: treating-to-target and definition of treatment goals
    Andrea Doria
    Division of Rheumatology, University of Padova, Padua, Italy Electronic address
    Autoimmun Rev 13:770-7. 2014
    ....
  47. doi Refractory pemphigus foliaceus and Behçet's disease successfully treated with tocilizumab
    Francesco Caso
    Division of Rheumatology, Department of Medicine, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
    Immunol Res 56:390-7. 2013
    ..Moreover, only two cases of BD and no cases of PF treated with tocilizumab have been described to date. A literature review on the use of biologic agents on patients with PF and BD was also carried out...
  48. ncbi Anterior chest wall involvement in early stages of spondyloarthritis: advanced diagnostic tools
    Roberta Ramonda
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, and Department of Radiology 1, Padua Hospital, Via Giustiniani 2, 35128 Padua, Italy
    J Rheumatol 39:1844-9. 2012
    ..Bone scan is sensitive to ACW involvement, while magnetic resonance imaging (MRI) detects early alterations in SpA. We compared the sensitivity and specificity of bone scans and MRI in assessing ACW in early SpA...
  49. doi Blau syndrome, clinical and genetic aspects
    Paolo Sfriso
    Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy
    Autoimmun Rev 12:44-51. 2012
    ..Clinical and genetic aspects of the familial and the sporadic form of BS will be discussed and focused on. A description of a case study of an Italian family is also included...
  50. doi Prognosis of scleroderma renal crisis: a long-term observational study
    Franco Cozzi
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Nephrol Dial Transplant 27:4398-403. 2012
    ..Our aim was to evaluate the prognosis of SRC in our cohort of scleroderma patients...
  51. ncbi Anti-SAE antibodies in autoimmune myositis: identification by unlabelled protein immunoprecipitation in an Italian patient cohort
    Elena Tarricone
    Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    J Immunol Methods 384:128-34. 2012
    ....
  52. ncbi Evidence of silicon dioxide crystals in synovial fluid of patients with osteoarthritis
    Francesca Oliviero
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    J Rheumatol 35:1092-5. 2008
    ..Scanning electron microscopy (SEM) was utilized in this study to characterize SF crystals in the context of knee osteoarthritis (OA)...
  53. ncbi CXCL11 in bronchoalveolar lavage fluid and pulmonary function decline in systemic sclerosis
    Paolo Sfriso
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Clin Exp Rheumatol 30:S71-5. 2012
    ..The aim of the present study was to determine whether the levels of CXCL11 in the bronchoalveolar lavage fluid (BALF) of SSc patients might be a predictor of clinically significant fibrotic lung involvement...
  54. doi The impact of knee and hip chondrocalcinosis on disability in older people: the ProVA Study from northeastern Italy
    Estella Musacchio
    Clinica Medica I, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Ann Rheum Dis 70:1937-43. 2011
    ..The role of osteoarthritis in the onset and progression of disability is well known. The impact of chondrocalcinosis on disability has never been investigated in epidemiological studies...
  55. ncbi Working the endless puzzle of hereditary autoinflammatory disorders
    Francesco Caso
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Mod Rheumatol 24:381-9. 2014
    ....
  56. doi The clinical features, diagnosis and classification of dermatomyositis
    Luca Iaccarino
    Rheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    J Autoimmun 48:122-7. 2014
    ....
  57. doi Serpins, immunity and autoimmunity: old molecules, new functions
    Mariele Gatto
    Division of Rheumatology, Department of Medicine, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
    Clin Rev Allergy Immunol 45:267-80. 2013
    ..Here, we provide an overview of serpin origin, function, and dysfunction, focusing on human serpins and ov-serpins, with a hub on SERPINB3...
  58. doi JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis
    Ugo Fiocco
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padua, Italy
    Immunol Res 58:61-9. 2014
    ....
  59. doi Autoantibodies in polymyositis and dermatomyositis
    Anna Ghirardello
    Department of Medicine, Division of Rheumatology, University of Padova, Padova, Italy
    Curr Rheumatol Rep 15:335. 2013
    ..This review article provides an update of new emerging insights about the clinical and pathophysiologic role of principal autoantibodies in myositis...
  60. doi Erosive hand osteoarthritis and systemic sclerosis: a casual association?
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Joint Bone Spine 79:507-9. 2012
    ..One of these is an unexpected association with some autoimmune diseases. EHOA and SSc in the same patient is not uncommon, and it could speculate that there may be a genetic and autoimmune involvement...
  61. pmc High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals
    Anna Scanu
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Arthritis Res Ther 12:R23. 2010
    ....
  62. ncbi Co-stimulatory modulation in rheumatoid arthritis: the role of (CTLA4-Ig) abatacept
    Ugo Fiocco
    Rheumatology Unit, University of Padova, Via Giustiniani 2 35128 Padova, Italy
    Autoimmun Rev 8:76-82. 2008
    ..CTLA4-Ig shows the capacity, either ex vivo or in vivo, to interrupt at multiple steps the ongoing inflammatory and destructive process, and to concur in restoring the immunoregulatory balance in RA...
  63. doi The tumor necrosis factor-{alpha}-blocking agent infliximab inhibits interleukin 1beta (IL-1beta) and IL-6 gene expression in human osteoblastic cells
    Estella Musacchio
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Rheumatol 36:1575-9. 2009
    ..Infliximab therapy in RA also had beneficial effects on local bone destruction and bone mineral density. We assessed effects of infliximab treatment on the bone tissue compartment and cytokine profile expression in vitro...
  64. doi A combination therapy protocol of plasmapheresis, intravenous immunoglobulins and betamethasone to treat anti-Ro/La-related congenital atrioventricular block. A case series and review of the literature
    Amelia Ruffatti
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Autoimmun Rev 12:768-73. 2013
    ..The aim of this report was to evaluate the efficacy and safety of a combined treatment protocol used to treat 2nd and 3rd degree anti-Ro/La-related congenital atrioventricular block (CAVB)...
  65. doi Rehabilitation treatment in patients with ankylosing spondylitis stabilized with tumor necrosis factor inhibitor therapy: a randomized controlled trial
    Stefano Masiero
    Rehabilitation Unit, Department of Rehabilitation, University of Padua, Padua, Italy
    J Rheumatol 38:1335-42. 2011
    ....
  66. ncbi Apolipoprotein A-I and cholesterol in synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis
    F Oliviero
    Department of Clinical and Experimental Medicine, University of Padova, Italy
    Clin Exp Rheumatol 27:79-83. 2009
    ..To investigate lipid and apolipoprotein (Apo) levels in synovial fluid (SF) and serum of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and osteoarthritis (OA)...
  67. ncbi Recommendations of the Italian Society for Rheumatology for the use of biologic (TNF-alpha blocking) agents in the treatment of psoriatic arthritis
    C Salvarani
    Rheumatology Unit, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
    Clin Exp Rheumatol 24:70-8. 2006
    ..To propose recommendations for the use of biologic (TNF-alpha blocking) agents in the treatment of psoriatic arthritis (PsA)...
  68. ncbi [Frequency of the bleeding risk in patients receiving warfarin submitted to arthrocentesis of the knee]
    G Salvati
    Cattedra e Divisione di Reumatologia, Universita degli Studi di Padova, Italia
    Reumatismo 55:159-63. 2003
    ..To evaluate the potential bleeding risks of arthrocentesis in patients with different arthropathies and taking oral anticoagulants...
  69. pmc Biological treatments: new weapons in the management of monogenic autoinflammatory disorders
    Antonio Vitale
    Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Viale Bracci 1, 53100 Siena, Italy
    Mediators Inflamm 2013:939847. 2013
    ..Aim of this review is to synthesize the current experience and the most recent evidences about the therapeutic approach with biologic drugs in pediatric and adult patients with monogenic autoinflammatory disorders. ..
  70. doi Long-term safety of anti-TNF-α in PsA patients with concomitant HCV infection: a retrospective observational multicenter study on 15 patients
    Luisa Costa
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University Federico II, Via S Pansini 5, 80131, Naples, Italy
    Clin Rheumatol 33:273-6. 2014
    ..The data suggests that anti-TNF-α agents are effective and safe in PsA patients with concomitant HCV. We suggest that the use of anti-TNF-α agents, accompanied by close monitoring, could be a therapeutic option...
  71. ncbi Influence of tumor necrosis factor α inhibitors on testicular function and semen in spondyloarthritis patients
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
    Fertil Steril 101:359-65. 2014
    ..To evaluate sperm parameters and sexual hormones in young males affected with spondyloarthritis (SpA) before and after 1 year of anti-tumor necrosis factor (TNF) α treatment...
  72. doi Joint and bone assessment in hand osteoarthritis
    Roberta Ramonda
    Rheumatology Unit, Department of Medicine DIMED, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy
    Clin Rheumatol 33:11-9. 2014
    ..This report focuses on the laboratory and clinimetric assessments that can be used to distinguish hand OA subtypes and addresses the debatable association with low bone mineral density in osteoporosis. ..
  73. ncbi Serum and salivary neopterin and interferon-gamma in primary Sjögren's syndrome. Correlation with clinical, laboratory and histopathologic features
    Paolo Sfriso
    Department of Medical and Surgical Sciences, Section of Rheumatology, University of Padova, Italy
    Scand J Rheumatol 32:74-8. 2003
    ..To investigate serum and salivary neopterin and interferon-gamma as possible markers of immune system activation in primary Sjögren's Syndrome (pSS)...
  74. ncbi Effects of an educational-behavioral joint protection program on people with moderate to severe rheumatoid arthritis: a randomized controlled trial
    Stefano Masiero
    Department of Rehabilitation Medicine, School of Medicine, University of Padova, Padova, Italy
    Clin Rheumatol 26:2043-50. 2007
    ..This approach may efficiently complement drug therapy in these patients...
  75. ncbi Tryptophan catabolism in synovial fluid of various arthropathies and its relationship with inflammatory cytokines
    A Bertazzo
    Department of Pharmaceutical Sciences, University of Padova, Italy
    Adv Exp Med Biol 467:565-70. 1999
    ..In addition, IDO activity seems to be related with the decrease in Trp, as demonstrated by the inverse correlation found between these two substances in the SF of all patients...
  76. ncbi [HDL inhibit cytokine production in a mouse model of urate crystal-induced inflammation]
    A Scanu
    Cattedra e U O C di Reumatologia, Universita di Padova, Padova, Italia
    Reumatismo 62:266-72. 2010
    ..To evaluate whether high density lipoproteins (HDL) affect monosodium urate (MSU) crystal-induced inflammation in the murine air pouch model...
  77. ncbi Sensorineural hearing loss in ankylosing spondylitis treated with TNF blockers
    M Savastano
    Department of Medical and Surgical Specialties, Section of Otolaryngology, University of Padova, Padova, Italy
    B-ENT 6:183-8. 2010
    ..Sensorineural hearing loss (SNHL) in the uncommon disease ankylosing spondylitis (AS) has been previously reported. We analysed the relationships between AS, anti-TNF drug treatment, and SNHL...
  78. doi Articular manifestations in inflammatory bowel disease patients: a prospective study
    R D'Inca
    Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
    Dig Liver Dis 41:565-9. 2009
    ..Rheumatic manifestations are frequent in inflammatory bowel disease (IBD) and are associated with a wide range of clinical patterns...
  79. ncbi [Crystal-induced joint inflammation]
    F Oliviero
    Cattedra e Divisione di Reumatologia, Universita degli Studi di Padova, Italia
    Reumatismo 55:16-27. 2003
    ..However, the final effect of the balance between inflammatory and anti-inflammatory cytokines may also depend by other tissutal and cellular factors, not all of which are still completely understood...
  80. ncbi [Critical analysis of the manoeuvres proposed for the diagnosis of the carpal tunnel syndrome]
    R Ramonda
    Cattedra e Divisione di Reumatologia, Dipartimento di Scienze Mediche e Chirurgiche, Universita degli Studi di Padova, Italia
    Reumatismo 54:156-64. 2002
    ..In this review we described and commented the tests considered most useful in the diagnosis of CTS. We also analysed the diagnostic values of electromyography, the most important electrodiagnostic study for the CTS...
  81. ncbi [Septic arthritis: a 12 years retrospective study in a rheumatological university clinic]
    M Favero
    Cattedra e UOC di Reumatologia, Universita di Padova, 35128 Padova, Italia
    Reumatismo 60:260-7. 2008
    ....
  82. ncbi Rheumatoid arthritis is the major risk factor for septic arthritis in rheumatological settings
    M Favero
    Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Autoimmun Rev 8:59-61. 2008
    ..For this reason the microscopic analysis and culture of synovial fluid are crucial to exclude septic arthritis...
  83. ncbi [The psoriatic great toe or the psoriatic onycho-pachydermo-periostitis of great toe (OP3gt)]
    R Ramonda
    Cattedra ed UOC di Reumatologia, Universita di Padova, 35128 Padova
    Reumatismo 56:282-5. 2004
    ..However, clinical manifestations, with inflammatory inflammation of the great toe, are rare...
  84. ncbi [Detection and identification of crystals in synovial fluid]
    F Oliviero
    Cattedra e Unità Operativa Complessa di Reumatologia, Universita di Padova, Via Giustiniani, 2 35128 Padova
    Reumatismo 57:208-11. 2005
    ..Due to its simple execution and high diagnostic value, this examine should be always performed to complete synovial fluid analysis...
  85. ncbi YKL-40 in human lumbar herniated disc and its relationships with nitric oxide and cyclooxygenase-2
    A Pozzuoli
    Department of Medical and Surgical Specialties, Orthopaedic Clinic, Rheumatology Unit, University Hospital of Padua
    Clin Exp Rheumatol 25:453-6. 2007
    ..Chitinase 3-like protein 1 (YKL-40) is a glycoprotein mainly secreted by chondrocytes which has been proposed as a possible marker of inflammation and/or cartilage alterations...
  86. ncbi [Synoviocyte cultures from synovial fluid]
    A Scanu
    Cattedra e U O C di Reumatologia, Universita di Padova, Padova, Italia
    Reumatismo 59:66-70. 2007
    ..The difficulties to achieve fresh human tissue prompted us to develop a simpler method to obtain fibroblast-like synovial cells from synovial fluid (SF)...
  87. ncbi [Utility of denaturing high performance liquid chromatography (DHPLC) for the diagnosis of mevalonate kinase deficiency in periodic disease]
    A Gava
    Cattedra e UOC di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Padova, Italia
    Reumatismo 61:187-96. 2009
    ..We developed a genetic investigation using denaturing high performance liquid chromatography (DHPLC), in order to identify polymorphisms of the gene MVK in patients with autoinflammatory syndrome suspicion...
  88. ncbi Adult Henoch-Schönlein purpura with glomerulonephritis and paroxysmal nocturnal haemoglobinuria: an uncommon association
    F Cozzi
    University of Padua, Padua, Italy
    Clin Rheumatol 21:408-10. 2002
    ..Bacterial infections, especially those of the respiratory and urinary tract, might trigger both the diseases...
  89. ncbi [Clinical value of antibodies to lysobisphosphatidic acid in patients with primary antiphospholipid syndrome]
    S Olivieri
    Cattedra e U O C di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Padova, Padova, Italia
    Reumatismo 62:107-12. 2010
    ..In conclusion, in view of our results anti-LBPA cannot at present be considered a further tool to be utilized to diagnose APS and to differentiate the different clinical and laboratory subsets of this disease...
  90. ncbi Psoriatic arthritis exacerbated by Salmonella infection
    L Punzi
    Division of Rheumatology, University of Padova, Italy
    Clin Rheumatol 19:167-8. 2000
    ..This case confirms the importance of infectious agents in the occurrence and course of PsA...
  91. ncbi Molecular pathways involved in synovial cell inflammation and tumoral proliferation in diffuse pigmented villonodular synovitis
    U Fiocco
    Unit of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Autoimmun Rev 9:780-4. 2010
    ..In the light of these observations, CSF1/CSF1R interaction probably represents a more sensible therapeutic target than TNF-alpha blockade in the diffuse form of pigmented villonodular synovitis...
  92. doi Laboratory and clinical features of pregnant women with antiphospholipid syndrome and neonatal outcome
    A Ruffatti
    University of Padua, Padua, Italy
    Arthritis Care Res (Hoboken) 62:302-7. 2010
    ..To evaluate the relationship between the antiphospholipid profile and clinical characteristics of pregnant women with antiphospholipid syndrome (APS) and neonatal outcome...
  93. ncbi Bactericidal/permeability increasing protein and proinflammatory cytokines in synovial fluid of psoriatic arthritis
    L Punzi
    Division of Rheumatology, University of Padova, Italy
    Clin Exp Rheumatol 18:613-5. 2000
    ..Its production may be stimulated by cytokines, mainly Tumor Necrosis Factor (TNF) alpha. We studied BPI in the synovial fluid (SF) of psoriatic arthritis (PsA), a disease suspected to be influenced by infectious agents...
  94. ncbi [The enthesopathy of vitamin D-resistant osteomalacia in adults]
    R Ramonda
    Universita di Padova, Via Giustiniani 2, 35128 Padova
    Reumatismo 57:52-6. 2005
    ..The calcified enthesopathy is an integral part of XLH and it is possible that it is found in adult because many years are necessary to produce it...
  95. ncbi Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. (PROgetto Veneto Anziani) study
    R Ramonda
    Cattedra e Divisione di Reumatologia, Dipartmento di Medicina Clinica e Sperimentale, Universita di Padova, Italy
    Clin Exp Rheumatol 27:981-4. 2009
    ..To undertake an epidemiological survey of the prevalence of radiological chondrocalcinosis (CC) of the lower limbs in the elderly Italian population of the Pro.V.A. study...
  96. ncbi Long-term therapy with plasma exchange in systemic sclerosis: effects on laboratory markers reflecting disease activity
    F Cozzi
    Division of Rheumatology, Universita di Padova, Italy
    Transfus Apher Sci 25:25-31. 2001
    ..Our data suggest that long-term PEX therapy seems to be effective in slowing down the clinical course of patients with severe and rapidly progressive SSc...
  97. ncbi [Anakinra, a recombinant human IL-1 receptor antagonist, in clinical practice. Outcome in 60 patients with severe rheumatoid arthritis]
    C Botsios
    Cattedra e U O C Reumatologia, Università Azienda Ospedaliera di Padova, Italia
    Reumatismo 59:32-7. 2007
    ..We evaluated both the efficacy and safety of anakinra in daily routine rheumatoid arthritis clinical practice...
  98. ncbi Immunogenetic aspects of erosive osteoarthritis of the hand in patients from northern Italy
    R Ramonda
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Scand J Rheumatol 40:139-44. 2011
    ..In the EHOA group we also sought possible associations between HLA alleles and disease severity...
  99. pmc Biomechanical assessment of balance and posture in subjects with ankylosing spondylitis
    Zimi Sawacha
    Department of Information Engineering, University of Padova, Padova, Italy
    J Neuroeng Rehabil 9:63. 2012
    ..The aim of this study was to develop a method for quantitatively and objectively assessing both balance and posture and their mutual relationship in ankylosing spondylitis subjects...
  100. doi Plasma exchange and immunoadsorption effectively remove antiphospholipid antibodies in pregnant patients with antiphospholipid syndrome
    Agnese Bontadi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    J Clin Apher 27:200-4. 2012
    ..0001, P = 0.0001, P = 0.001). The fall in IgG aβ(2)GPI was significant in two of the patients (P = 0.0001, P = 0.0001) both with high antibody titers, but not in one with medium antibody titers, who was treated with PE (P = 0.17)...
  101. doi Gastric dysmotility after liquid bolus ingestion in systemic sclerosis: an ultrasonographic study
    Franco Cozzi
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Rheumatol Int 32:1219-23. 2012
    ..Our findings show that gastric dysmotility is frequent and severe in SSc patients, contributing to the gastrointestinal disturbances which are very common in this disease...