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Genomes and Genes | Leonardo PunziSummaryAffiliation: University of Padova Country: Italy Publications
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Publications
Erosive osteoarthritisLeonardo Punzi
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
Best Pract Res Clin Rheumatol 18:739-58. 2004..No definitive therapeutic approach to EOA has been reported. It is reasonable to assume that in the presence of a symptomatic EOA our therapeutic approach should differ from that used for common, nodal, non-EOA...
Effect of Helicobacter pylori and eradication therapy on gastrointestinal permeability. Implications for patients with seronegative spondyloarthritisVincenza Di Leo
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
J Rheumatol 32:295-300. 2005..CONCLUSION: In SpA, H. pylori and NSAID contribute to impaired GI permeability. Eradication therapy may help to maintain epithelial barrier function and possibly influence clinical improvement in patients with SpA...
Tinnitus and bilateral sensorineural hearing loss: ankylosing spondylitis or a side-effect of sulphasalazine treatment?Marina Savastano
Department of Otolaryngology Head and Neck Surgery, University of Padua, Padua, Italy
Acta Otolaryngol 125:671-3. 2005..Discontinuation of sulphasalazine led to complete resolution of tinnitus and an improvement in hearing loss. We discuss the features of this case and also review the relevant literature...
Epithelial CXCR3-B regulates chemokines bioavailability in normal, but not in Sjogren's syndrome, salivary glandsPaolo Sfriso
Department of Clinical and Experimental Medicine, Section of Rheumatology, Centro di Eccellenza per la Ricerca Biomedica, Padova, Italy
J Immunol 176:2581-9. 2006..They also support a critical role for CXCR3 in the pathogenesis of SS and identify its agonists as potential therapeutic targets...
Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trialFranco Cozzi
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Joint Bone Spine 74:436-9. 2007..The objective of this study was to evaluate the effects and the tolerability of mud packs and thermal baths in a group of patients affected with this disease...
Gout as autoinflammatory disease: new mechanisms for more appropriated treatment targetsLeonardo Punzi
Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
Autoimmun Rev 12:66-71. 2012..All these aspects, leading to deeper insight, have suggested new treatments, some of which are already available while others are likely to become available in the near future...
Coll2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the handsL Punzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
Osteoarthritis Cartilage 20:557-61. 2012....
Psoriatic arthritis. When the heterogeneity requires normalityL Punzi
University of Padova
Reumatismo 64:59-65. 2012..This seems obtained with a convenient cost-effectiveness ratio...
Miscellaneous non-inflammatory musculoskeletal conditions. Blau syndromeLeonardo Punzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
Best Pract Res Clin Rheumatol 25:703-14. 2011..This review will focus on the clinical and genetics aspects of the familial and the sporadic form of BS. Further, we will describe an Italian family followed by us over the past 25 years...
Metabolism of crystals within the jointF Oliviero
University of Padova
Reumatismo 63:221-9. 2012..We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation...
Inflammatory osteoarthritis of the handLeonardo Punzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Best Pract Res Clin Rheumatol 24:301-12. 2010..Thus, it is probably preferable to use the double term inflammatory/erosive to better define this particular subset of HOA...
Chronic autoimmune thyroiditis and rheumatic manifestationsLeonardo Punzi
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, Padova 35128, Italy
Joint Bone Spine 71:275-83. 2004....
[Italian consensus on Eular 2003 recommendations for the treatment of knee osteoarthritis]L Punzi
Cattedra ed UOC di Reumatologia, Universita di Padova, Padova
Reumatismo 56:190-201. 2004..Furthermore, the final document of the Italian Consensus clearly indicated the need that specialists involved in the management of knee OA strongly encourage the dissemination of the EULAR 2003 recommendations also in Italy...
Clinical significance of cytokine determination in synovial fluidLeonardo Punzi
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
Crit Rev Clin Lab Sci 39:63-88. 2002..Furthermore, as some of these cytokines may reflect disease activity, their determination may also be useful in the evaluation of therapy...
Pathogenetic and clinical rationale for TNF-blocking therapy in psoriatic arthritisLeonardo Punzi
Rheumatology Unit, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Autoimmun Rev 6:524-8. 2007..In this new fashion, the most stimulating hypotheses involving TNF are those regarding genetic predisposition, angiogenesis and osteoclastogenesis...
Value of C reactive protein in the assessment of erosive osteoarthritis of the handL Punzi
Cattedra e Divisione di Reumatologia, Universita di Padova, Via Giustiniani, 235128 Padua, Italy
Ann Rheum Dis 64:955-7. 2005..To investigate the value of serum C reactive protein (CRP) as a marker of erosive osteoarthritis (EOA) of the hand...
Arthrocentesis and synovial fluid analysis in clinical practice: value of sonography in difficult casesLeonardo Punzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padua, Italy
Ann N Y Acad Sci 1154:152-8. 2009..Furthermore, ultrasonography may be useful in revealing the presence of synovial fluid before the joint aspiration and, subsequently, distinguishing some aspects characteristic of crystal-induced arthropathies...
Laboratory findings in osteoarthritisLeonardo Punzi
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Semin Arthritis Rheum 34:58-61. 2005
Laboratory findings in psoriatic arthritisL Punzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
Reumatismo 59:52-5. 2007....
[Italian Society of Rheumatology (SIR) recommendations for performing arthrocentesis]L Punzi
Cattedra ed UOC Reumatologia, Universita di Padova, Italia
Reumatismo 59:227-34. 2007..Several of these recommendations were based on experts' opinion rather than on published evidence which is scanty...
Clinical and genetic aspects of Blau syndrome: a 25-year follow-up of one family and a literature reviewLeonardo Punzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Italy
Autoimmun Rev 8:228-32. 2009..As in Crohn's disease, CARD15/NOD2 mutation is believed to be responsible for the granulomatous autoinflammatory reactions probably triggered by microorganisms in BS...
New horizons in osteoarthritisF Oliviero
Department of Clinical and Experimental Rheumatology, University of Padova, Via Giustiniani, Padova, IT
Swiss Med Wkly 140:w13098. 2010..Numerous new substances have been formulated and the findings of trials studying their effects are encouraging, although much has yet to be done...
[Italian consensus on EULAR recommendations 2005 for the management of hip osteoarthritis]L Punzi
Cattedra ed Unità Operativa di Reumatologia, Universita di Padova, Italia
Reumatismo 58:301-9. 2006..Furthermore, the final document of the Italian Consensus clearly indicated the need that the specialists involved in the management of hip OA strongly encourage the dissemination of the EULAR 2005 recommendations also in Italy...
New biochemical insights into the pathogenesis of osteoarthritis and the role of laboratory investigations in clinical assessmentLeonardo Punzi
Division of Rheumatology, University of Padova, Italy
Crit Rev Clin Lab Sci 42:279-309. 2005....
Serum human cartilage glycoprotein 39 as a marker of arthritis associated with inflammatory bowel diseaseL Punzi
Division of Rheumatology, University of Padova, Italy
Ann Rheum Dis 62:1224-6. 2003..Common blood markers of arthritis are difficult to interpret in arthritis associated with inflammatory bowel disease (IBD) owing to the coexistence of two inflammatory events. No specific serological disease marker is available for IBD...
Laboratory investigations in osteoarthritisLeonardo Punzi
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Aging Clin Exp Res 15:373-9. 2003....
Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditisLeonardo Punzi
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Semin Arthritis Rheum 32:51-5. 2002..Our study aims to characterize arthralgia and, in particular, polyarthralgia (PA) associated with CLT and to evaluate the influence of thyroid replacement therapy...
Disease activity patterns in a monocentric cohort of SLE patients: a seven-year follow-up studyMargherita Zen
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
Clin Exp Rheumatol 30:856-63. 2012..To evaluate disease activity patterns and flare occurrence in a cohort of systemic lupus erythematosus (SLE) patients...
Synovial biomarkers in psoriatic arthritisUgo Fiocco
Department of Medicine, University of Padua, Padua, Italy
J Rheumatol Suppl 89:61-4. 2012..5 mg)...
Elderly onset of primary Sjögren's syndrome: clinical manifestations, serological features and oral/ocular diagnostic tests. Comparison with adult and young onset of the disease in a cohort of 336 Italian patientsCostantino Botsios
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Joint Bone Spine 78:171-4. 2011..To study and compare the clinical and serological features of patients with elderly versus adult and younger onset of primary Sjögren's syndrome (pSS)...
Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phaseAnna Scanu
Rheumatology Unit, Department of Medicine, University of Padova, Italy
Ann Rheum Dis 71:621-4. 2012..To determine the most relevant parameters in synovial fluid (SF) during the various stages of acute gout...
Synovial effusion and synovial fluid biomarkers in psoriatic arthritis to assess intraarticular tumor necrosis factor-α blockade in the knee jointUgo Fiocco
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Arthritis Res Ther 12:R148. 2010....
Blockade of intra-articular TNF in peripheral spondyloarthritis: its relevance to clinical scores, quantitative imaging and synovial fluid and synovial tissue biomarkersUgo Fiocco
Department of Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Joint Bone Spine 80:165-70. 2013....
Overlap connective tissue disease syndromesLuca Iaccarino
Division of Rheumatology, Department of Medicine, University of Padua, Italy
Autoimmun Rev 12:363-73. 2013..In this paper the most frequent OS are described with a special focus on the specific immunologic and clinical aspects. Furthermore, some personal data on anti-t-RNA synthetase syndrome and rhupus syndrome are reported...
Anterior chest wall involvement in early stages of spondyloarthritis: advanced diagnostic toolsRoberta Ramonda
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, and Department of Radiology 1, Padua Hospital, Via Giustiniani 2, 35128 Padua, Italy
J Rheumatol 39:1844-9. 2012..Bone scan is sensitive to ACW involvement, while magnetic resonance imaging (MRI) detects early alterations in SpA. We compared the sensitivity and specificity of bone scans and MRI in assessing ACW in early SpA...
Emerging and critical issues in the pathogenesis of lupusMariele Gatto
Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Autoimmun Rev 12:523-36. 2013..e. genetic predisposition, B and T cell abnormalities, abnormal autoantigen availability, autoantibody generation and organ damage, relying on current knowledge and recent insights into SLE development...
Prognosis of scleroderma renal crisis: a long-term observational studyFranco Cozzi
Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
Nephrol Dial Transplant 27:4398-403. 2012..Our aim was to evaluate the prognosis of SRC in our cohort of scleroderma patients...
Blau syndrome, clinical and genetic aspectsPaolo Sfriso
Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy
Autoimmun Rev 12:44-51. 2012..Clinical and genetic aspects of the familial and the sporadic form of BS will be discussed and focused on. A description of a case study of an Italian family is also included...
Anti-SAE antibodies in autoimmune myositis: identification by unlabelled protein immunoprecipitation in an Italian patient cohortElena Tarricone
Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
J Immunol Methods 384:128-34. 2012....
Evidence of silicon dioxide crystals in synovial fluid of patients with osteoarthritisFrancesca Oliviero
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
J Rheumatol 35:1092-5. 2008..Scanning electron microscopy (SEM) was utilized in this study to characterize SF crystals in the context of knee osteoarthritis (OA)...
CXCL11 in bronchoalveolar lavage fluid and pulmonary function decline in systemic sclerosisPaolo Sfriso
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Clin Exp Rheumatol 30:S71-5. 2012..The aim of the present study was to determine whether the levels of CXCL11 in the bronchoalveolar lavage fluid (BALF) of SSc patients might be a predictor of clinically significant fibrotic lung involvement...
The impact of knee and hip chondrocalcinosis on disability in older people: the ProVA Study from northeastern ItalyEstella Musacchio
Clinica Medica I, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Ann Rheum Dis 70:1937-43. 2011..The role of osteoarthritis in the onset and progression of disability is well known. The impact of chondrocalcinosis on disability has never been investigated in epidemiological studies...
High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystalsAnna Scanu
Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Arthritis Res Ther 12:R23. 2010....
The effects of combined spa therapy and rehabilitation on patients with ankylosing spondylitis being treated with TNF inhibitorsLuca Ciprian
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Rheumatol Int 33:241-5. 2013..Combined spa therapy and rehabilitation caused a clear, long-term clinical improvement in AS patients being treated with TNF inhibitors. Thermal treatment was found to be well tolerated and none of the patients had disease relapse...
The tumor necrosis factor-{alpha}-blocking agent infliximab inhibits interleukin 1beta (IL-1beta) and IL-6 gene expression in human osteoblastic cellsEstella Musacchio
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
J Rheumatol 36:1575-9. 2009..Infliximab therapy in RA also had beneficial effects on local bone destruction and bone mineral density. We assessed effects of infliximab treatment on the bone tissue compartment and cytokine profile expression in vitro...
Co-stimulatory modulation in rheumatoid arthritis: the role of (CTLA4-Ig) abataceptUgo Fiocco
Rheumatology Unit, University of Padova, Via Giustiniani 2 35128 Padova, Italy
Autoimmun Rev 8:76-82. 2008..CTLA4-Ig shows the capacity, either ex vivo or in vivo, to interrupt at multiple steps the ongoing inflammatory and destructive process, and to concur in restoring the immunoregulatory balance in RA...
Treatment of 139 Pregnancies in Antiphospholipid-positive Women Not Fulfilling Criteria for Antiphospholipid Syndrome: A Retrospective StudyTeresa Del Ross
From the Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padua, Italy
J Rheumatol 40:425-9. 2013..The effect of low-dose aspirin (LDA) on pregnancy outcome in antiphospholipid (aPL)-positive women not fulfilling the criteria for antiphospholipid antibody syndrome (APS) was evaluated retrospectively...
Serological markers of erosive hand osteoarthritisRoberta Ramonda
Rheumatology Unit, Department of Medicine DIMED, University of Padova, Italy
Eur J Intern Med 24:11-5. 2013....
Rehabilitation treatment in patients with ankylosing spondylitis stabilized with tumor necrosis factor inhibitor therapy: a randomized controlled trialStefano Masiero
Rehabilitation Unit, Department of Rehabilitation, University of Padua, Padua, Italy
J Rheumatol 38:1335-42. 2011....
Methods used to assess remission and low disease activity in rheumatoid arthritisFrancesca Ometto
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, 35128 Padova, Italy
Autoimmun Rev 9:161-4. 2010..Thus, those reported by FDA are the only criteria for remission which consider radiographic arrest of the disease. This review aims to describe the criteria for RA remission and to discuss their advantages and limitations...
Apolipoprotein A-I and cholesterol in synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritisF Oliviero
Department of Clinical and Experimental Medicine, University of Padova, Italy
Clin Exp Rheumatol 27:79-83. 2009..To investigate lipid and apolipoprotein (Apo) levels in synovial fluid (SF) and serum of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and osteoarthritis (OA)...
Recommendations of the Italian Society for Rheumatology for the use of biologic (TNF-alpha blocking) agents in the treatment of psoriatic arthritisC Salvarani
Rheumatology Unit, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
Clin Exp Rheumatol 24:70-8. 2006..To propose recommendations for the use of biologic (TNF-alpha blocking) agents in the treatment of psoriatic arthritis (PsA)...
[Frequency of the bleeding risk in patients receiving warfarin submitted to arthrocentesis of the knee]G Salvati
Cattedra e Divisione di Reumatologia, Universita degli Studi di Padova, Italia
Reumatismo 55:159-63. 2003..To evaluate the potential bleeding risks of arthrocentesis in patients with different arthropathies and taking oral anticoagulants...
Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitroFrancesca Oliviero
Rheumatology Unit, Department of Medicine, University of Padova Padova, Italy
Front Pharmacol 4:51. 2013....
Erosive hand osteoarthritis and systemic sclerosis: A casual association?Roberta Ramonda
Rheumatology Unit, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy Electronic address
Joint Bone Spine 79:507-9. 2012..One of these is an unexpected association with some autoimmune diseases. EHOA and SSc in the same patient is not uncommon, and it could speculate that there may be a genetic and autoimmune involvement...
Effect of pregnancy on serum cytokines in SLE patientsAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, 35128, Italy
Arthritis Res Ther 14:R66. 2012..The aim of this study was to evaluate an extensive panel of cytokines involved in immune regulation during pregnancy in patients with systemic lupus erythematosus (SLE) and in healthy women...
Serum and salivary neopterin and interferon-gamma in primary Sjögren's syndrome. Correlation with clinical, laboratory and histopathologic featuresPaolo Sfriso
Department of Medical and Surgical Sciences, Section of Rheumatology, University of Padova, Italy
Scand J Rheumatol 32:74-8. 2003..CONCLUSION: In pSS patients serum neopterin may represent a useful marker of cell-mediated immunity. On the other hand, salivary neopterin seems to reflect theglandular damage...
Effects of an educational-behavioral joint protection program on people with moderate to severe rheumatoid arthritis: a randomized controlled trialStefano Masiero
Department of Rehabilitation Medicine, School of Medicine, University of Padova, Padova, Italy
Clin Rheumatol 26:2043-50. 2007..This approach may efficiently complement drug therapy in these patients...
Molecular pathways involved in synovial cell inflammation and tumoral proliferation in diffuse pigmented villonodular synovitisU Fiocco
Unit of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Autoimmun Rev 9:780-4. 2010..In the light of these observations, CSF1/CSF1R interaction probably represents a more sensible therapeutic target than TNF-alpha blockade in the diffuse form of pigmented villonodular synovitis...
Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. (PROgetto Veneto Anziani) studyR Ramonda
Cattedra e Divisione di Reumatologia, Dipartmento di Medicina Clinica e Sperimentale, Universita di Padova, Italy
Clin Exp Rheumatol 27:981-4. 2009..To undertake an epidemiological survey of the prevalence of radiological chondrocalcinosis (CC) of the lower limbs in the elderly Italian population of the Pro.V.A. study...
Laboratory and clinical features of pregnant women with antiphospholipid syndrome and neonatal outcomeA Ruffatti
University of Padua, Padua, Italy
Arthritis Care Res (Hoboken) 62:302-7. 2010..To evaluate the relationship between the antiphospholipid profile and clinical characteristics of pregnant women with antiphospholipid syndrome (APS) and neonatal outcome...
[HDL inhibit cytokine production in a mouse model of urate crystal-induced inflammation]A Scanu
Cattedra e U O C di Reumatologia, Universita di Padova, Padova, Italia
Reumatismo 62:266-72. 2010..To evaluate whether high density lipoproteins (HDL) affect monosodium urate (MSU) crystal-induced inflammation in the murine air pouch model...
Sensorineural hearing loss in ankylosing spondylitis treated with TNF blockersM Savastano
Department of Medical and Surgical Specialties, Section of Otolaryngology, University of Padova, Padova, Italy
B-ENT 6:183-8. 2010..Sensorineural hearing loss (SNHL) in the uncommon disease ankylosing spondylitis (AS) has been previously reported. We analysed the relationships between AS, anti-TNF drug treatment, and SNHL...
[Clinical value of antibodies to lysobisphosphatidic acid in patients with primary antiphospholipid syndrome]S Olivieri
Cattedra e U O C di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Padova, Padova, Italia
Reumatismo 62:107-12. 2010..In conclusion, in view of our results anti-LBPA cannot at present be considered a further tool to be utilized to diagnose APS and to differentiate the different clinical and laboratory subsets of this disease...
[Utility of denaturing high performance liquid chromatography (DHPLC) for the diagnosis of mevalonate kinase deficiency in periodic disease]A Gava
Cattedra e UOC di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Padova, Italia
Reumatismo 61:187-96. 2009..We developed a genetic investigation using denaturing high performance liquid chromatography (DHPLC), in order to identify polymorphisms of the gene MVK in patients with autoinflammatory syndrome suspicion...
Psoriatic arthritis exacerbated by Salmonella infectionL Punzi
Division of Rheumatology, University of Padova, Italy
Clin Rheumatol 19:167-8. 2000..This case confirms the importance of infectious agents in the occurrence and course of PsA...
[Detection and identification of crystals in synovial fluid]F Oliviero
Cattedra e Unità Operativa Complessa di Reumatologia, Universita di Padova, Via Giustiniani, 2 35128 Padova
Reumatismo 57:208-11. 2005..Due to its simple execution and high diagnostic value, this examine should be always performed to complete synovial fluid analysis...
[The enthesopathy of vitamin D-resistant osteomalacia in adults]R Ramonda
Universita di Padova, Via Giustiniani 2, 35128 Padova
Reumatismo 57:52-6. 2005..The calcified enthesopathy is an integral part of XLH and it is possible that it is found in adult because many years are necessary to produce it...
Tryptophan catabolism in synovial fluid of various arthropathies and its relationship with inflammatory cytokinesA Bertazzo
Department of Pharmaceutical Sciences, University of Padova, Italy
Adv Exp Med Biol 467:565-70. 1999..In addition, IDO activity seems to be related with the decrease in Trp, as demonstrated by the inverse correlation found between these two substances in the SF of all patients...
[The psoriatic great toe or the psoriatic onycho-pachydermo-periostitis of great toe (OP3gt)]R Ramonda
Cattedra ed UOC di Reumatologia, Universita di Padova, 35128 Padova
Reumatismo 56:282-5. 2004..However, clinical manifestations, with inflammatory inflammation of the great toe, are rare...
[Crystal-induced joint inflammation]F Oliviero
Cattedra e Divisione di Reumatologia, Universita degli Studi di Padova, Italia
Reumatismo 55:16-27. 2003..However, the final effect of the balance between inflammatory and anti-inflammatory cytokines may also depend by other tissutal and cellular factors, not all of which are still completely understood...
Adult Henoch-Schönlein purpura with glomerulonephritis and paroxysmal nocturnal haemoglobinuria: an uncommon associationF Cozzi
University of Padua, Padua, Italy
Clin Rheumatol 21:408-10. 2002..Bacterial infections, especially those of the respiratory and urinary tract, might trigger both the diseases...
[Critical analysis of the manoeuvres proposed for the diagnosis of the carpal tunnel syndrome]R Ramonda
Cattedra e Divisione di Reumatologia, Dipartimento di Scienze Mediche e Chirurgiche, Universita degli Studi di Padova, Italia
Reumatismo 54:156-64. 2002..In this review we described and commented the tests considered most useful in the diagnosis of CTS. We also analysed the diagnostic values of electromyography, the most important electrodiagnostic study for the CTS...
Long-term therapy with plasma exchange in systemic sclerosis: effects on laboratory markers reflecting disease activityF Cozzi
Division of Rheumatology, Universita di Padova, Italy
Transfus Apher Sci 25:25-31. 2001..Our data suggest that long-term PEX therapy seems to be effective in slowing down the clinical course of patients with severe and rapidly progressive SSc...
Bactericidal/permeability increasing protein and proinflammatory cytokines in synovial fluid of psoriatic arthritisL Punzi
Division of Rheumatology, University of Padova, Italy
Clin Exp Rheumatol 18:613-5. 2000..Its production may be stimulated by cytokines, mainly Tumor Necrosis Factor (TNF) alpha. We studied BPI in the synovial fluid (SF) of psoriatic arthritis (PsA), a disease suspected to be influenced by infectious agents...
[Synoviocyte cultures from synovial fluid]A Scanu
Cattedra e U O C di Reumatologia, Universita di Padova, Padova, Italia
Reumatismo 59:66-70. 2007..The difficulties to achieve fresh human tissue prompted us to develop a simpler method to obtain fibroblast-like synovial cells from synovial fluid (SF)...
YKL-40 in human lumbar herniated disc and its relationships with nitric oxide and cyclooxygenase-2A Pozzuoli
Department of Medical and Surgical Specialties, Orthopaedic Clinic, Rheumatology Unit, University Hospital of Padua
Clin Exp Rheumatol 25:453-6. 2007..Chitinase 3-like protein 1 (YKL-40) is a glycoprotein mainly secreted by chondrocytes which has been proposed as a possible marker of inflammation and/or cartilage alterations...
[TNFalpha blockers and infectious risk in rheumatoid arthritis]B Raffeiner
Cattedra e U O C di Reumatologia, Dipartimento Medicina Clinica e Sperimentale, Universita di Padova, Italia
Reumatismo 61:165-73. 2009..Physicians should carefully monitor for signs of infection when using TNF alpha blockers, particularly shortly after treatment initiation...
Articular manifestations in inflammatory bowel disease patients: a prospective studyR D'Inca
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Dig Liver Dis 41:565-9. 2009..Rheumatic manifestations are frequent in inflammatory bowel disease (IBD) and are associated with a wide range of clinical patterns...
[Septic arthritis: a 12 years retrospective study in a rheumatological university clinic]M Favero
Cattedra e UOC di Reumatologia, Universita di Padova, 35128 Padova, Italia
Reumatismo 60:260-7. 2008....
[Anakinra, a recombinant human IL-1 receptor antagonist, in clinical practice. Outcome in 60 patients with severe rheumatoid arthritis]C Botsios
Cattedra e U O C Reumatologia, Università Azienda Ospedaliera di Padova, Italia
Reumatismo 59:32-7. 2007..We evaluated both the efficacy and safety of anakinra in daily routine rheumatoid arthritis clinical practice...
Rheumatoid arthritis is the major risk factor for septic arthritis in rheumatological settingsM Favero
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
Autoimmun Rev 8:59-61. 2008..For this reason the microscopic analysis and culture of synovial fluid are crucial to exclude septic arthritis...
Immunogenetic aspects of erosive osteoarthritis of the hand in patients from northern ItalyR Ramonda
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Scand J Rheumatol 40:139-44. 2011..36 ± 23 vs. 64.5 ± 18.5, p = 0.029). Conclusion: In this study of North Italian patients affected with EHOA, the HLA-DRB1*07 allele was found to be associated with both the development and greater severity of the disease...
Biomechanical assessment of balance and posture in subjects with ankylosing spondylitisZimi Sawacha
Department of Information Engineering, University of Padova, Padova, Italy
J Neuroeng Rehabil 9:63. 2012..The aim of this study was to develop a method for quantitatively and objectively assessing both balance and posture and their mutual relationship in ankylosing spondylitis subjects...
Autoantibodies in polymyositis and dermatomyositisAnna Ghirardello
Department of Medicine, Division of Rheumatology, University of Padova, Padova, Italy
Curr Rheumatol Rep 15:335. 2013..This review article provides an update of new emerging insights about the clinical and pathophysiologic role of principal autoantibodies in myositis...
Plasma exchange and immunoadsorption effectively remove antiphospholipid antibodies in pregnant patients with antiphospholipid syndromeAgnese Bontadi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
J Clin Apher 27:200-4. 2012..0001, P = 0.0001, P = 0.001). The fall in IgG aβ(2)GPI was significant in two of the patients (P = 0.0001, P = 0.0001) both with high antibody titers, but not in one with medium antibody titers, who was treated with PE (P = 0.17)...
Gastric dysmotility after liquid bolus ingestion in systemic sclerosis: an ultrasonographic studyFranco Cozzi
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Rheumatol Int 32:1219-23. 2012..Our findings show that gastric dysmotility is frequent and severe in SSc patients, contributing to the gastrointestinal disturbances which are very common in this disease...
Pregnancy and vasculitis: a systematic review of the literatureMariele Gatto
Division of Rheumatology, Department of Medicine, University of Padova, Padova, Italy
Autoimmun Rev 11:A447-59. 2012..Furthermore, organ failure or damage must be carefully considered, since it can lead to adverse obstetrical and fetal outcomes...
Fibromyalgia in Italian patients with primary Sjögren's syndromePierantonio Ostuni
Department of Medical and Surgical Sciences, University of Padova, Italy
Joint Bone Spine 69:51-7. 2002....
[Prevalence of erosive osteoarthritis of the hand in a population from Venetian area]F Cavasin
Cattedra e Divisione di Reumatologia, , Padua
Reumatismo 56:46-50. 2004..5 +/-10.1 years (range 41-74) mean disease duration 5.1 +/-3.8 years (range 1-15). The most frequently involved joint was the second DIP of the right hand. CONCLUSION: The prevalence of EOA in the Venetian area seems to be around 8.5%...
Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: comparison of adalimumab, etanercept and infliximab in the GISEA registryFabiola Atzeni
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Autoimmun Rev 12:225-9. 2012..To evaluate the risk of serious infections (SIs) in RA patients receiving anti-TNF therapy on the basis of the data included in the GISEA register...
Autoinflammatory diseases: how to put the fire inside the body out?Andrea Doria
Division of Rheumatology, Department of Medicine, University of Padova, Padova, Italy
Autoimmun Rev 12:1-4. 2012..In this issue of Autoimmunity Reviews some novel and burning aspects of AIDs were covered and the relationship between AIDs and autoimmune diseases was discussed...
Miscellaneous non-inflammatory musculoskeletal conditions. Bartter's and Gitelman's diseasesMarta Favero
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2, Padua, Italy
Best Pract Res Clin Rheumatol 25:637-48. 2011..Rheumatologists should be aware of the association between Gitelman's syndrome and CPPD, and should consider this metabolic disorder when CPPD occurs in younger patients...
Dermatomyositis and malignancy of the pharynx in Caucasian patients: report of two observationsC Botsios
Division of Rheumatology, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
Rheumatol Int 23:309-11. 2003..We report two cases of Caucasian Italian patients with dermatomyositis associated, respectively, with nasopharyngeal and tonsillar carcinomas. The relationship between dermatomyositis and malignancy is also discussed...
Pregnancy, cytokines, and disease activity in systemic lupus erythematosusAndrea Doria
University of Padova, Padova, Italy
Arthritis Rheum 51:989-95. 2004..To evaluate levels of selected cytokines and soluble receptors involved in the humoral immune response during pregnancy in systemic lupus erythematosus (SLE) patients...
Influence of glucosamine sulphate on oxidative stress in human osteoarthritic chondrocytes: effects on HO-1, p22(Phox) and iNOS expressionC Valvason
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2 35128 Padova, Italy
Rheumatology (Oxford) 47:31-5. 2008..The aim of the present study was to investigate the effects of GS on primary human chondrocytes in vitro, in particular with regard to HO-1, p22(Phox) (a subunit of NADPH complex) and inducible nitric oxide synthase (iNOS) expression...
[On the main stages of the history of intra-articular therapy]P Marson
U O Immunotrasfusionale, Azienda Ospedale Università di Padova, Padova, Italia
Reumatismo 59:262-8. 2007..Future of intra-articular treatment should be represented by the biological drugs, i.e., anti-TNF, but it is still untimely to define the exact role of such a local treatment of arthritis...
[Confirmation of antiphospholipid antibody positivity: a year's results in a cohort of 113 patients]S Cuffaro
Cattedra e U O C di Reumatologia, Universita di Padova, Padova, Italia
Reumatismo 62:51-9. 2010..To evaluate the confirmation rate of antiphospholipid antibodies (aPL), to analyze their behaviour at confirmation time, and to study the clinical value of their confirmation...
Pro-inflammatory interleukins in the synovial fluid of rheumatoid arthritis associated with joint hypermobilityL Punzi
Division of Rheumatology, University of Padova, Italy
Rheumatology (Oxford) 40:202-4. 2001..CONCLUSION: In JH-RA, increased joint mobility seems to be associated with a more severe local inflammatory response, which may contribute to the more erosive evolution observed in our patients...
[Subclinical atherosclerosis in patients with psoriatic arthritis: a case-control study. Preliminary data]C Contessa
Dipartimento di Medicina Clinica e Sperimentale, Universita di Padova, Italia
Reumatismo 61:298-305. 2009..The aim of this study was to evaluate the prevalence of subclinical atherosclerosis in patients with psoriatic arthritis (PsA), correlated with some traditional risk factors of atherosclerosis and with PsA-related disease factors...
Distribution of HLA-B27 subtypes in Sardinia and continental Italy and their association with spondylarthropathiesFabiana Paladini
University La Sapienza, Rome, Italy
Arthritis Rheum 52:3319-21. 2005
