F Puglisi

Summary

Affiliation: University of Udine
Country: Italy

Publications

  1. pmc Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report
    Gianpiero Fasola
    Dept of Medical Oncology, University Hospital, P le S M Misericordia, 33100 Udine, Italy
    BMC Cancer 6:289. 2006
  2. pmc HEX expression and localization in normal mammary gland and breast carcinoma
    Cinzia Puppin
    Dipartimento di Scienze e Tecnologie Biomediche, Universita di Udine, Italy
    BMC Cancer 6:192. 2006
  3. ncbi Expression of Pax-8, p53 and bcl-2 in human benign and malignant thyroid diseases
    F Puglisi
    Institute of Clinical Oncology, University of Udine, Italy
    Anticancer Res 20:311-6. 2000
  4. ncbi Prognostic significance of Ape1/ref-1 subcellular localization in non-small cell lung carcinomas
    F Puglisi
    University of Udine, Italy
    Anticancer Res 21:4041-9. 2001
  5. ncbi Role of mammography, ultrasound and large core biopsy in the diagnostic evaluation of papillary breast lesions
    Fabio Puglisi
    Clinical Oncology, Breast Unit, Breast Unit, University of Udine, Udine, Italy
    Oncology 65:311-5. 2003
  6. ncbi Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas
    Fabio Puglisi
    Clinica Oncologica, Policlinico Universitario, Piazzale S M Misericordia I 33100 Udine, Italy
    Oncol Rep 9:11-7. 2002
  7. ncbi Galectin-3 expression in non-small cell lung carcinoma
    Fabio Puglisi
    Clinical Oncology, University of Udine, Italy
    Cancer Lett 212:233-9. 2004
  8. ncbi Tumor shrinkage evaluation during and after preoperative doxorubicin and cyclophosphamide followed by docetaxel in patients with breast cancer
    Fabio Puglisi
    Clinical Oncology, Breast Unit, University of Udine, Udine, Italy
    Anticancer Res 24:2487-93. 2004
  9. ncbi Combined analysis of MIB-1 and thyroid transcription factor-1 predicts survival in non-small cell lung carcinomas
    F Puglisi
    Department of Clinical Oncology, University of Udine, Piazzale SM Misericordia, 33100, Udine, Italy
    Cancer Lett 162:97-103. 2001
  10. ncbi Baseline staging tests after a new diagnosis of breast cancer: further evidence of their limited indications
    F Puglisi
    Breast Unit and Clinical Oncology, University of Udine, Piazzale SM Misericordia, 33100 Udine, Italy
    Ann Oncol 16:263-6. 2005

Detail Information

Publications54

  1. pmc Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report
    Gianpiero Fasola
    Dept of Medical Oncology, University Hospital, P le S M Misericordia, 33100 Udine, Italy
    BMC Cancer 6:289. 2006
    ..To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options...
  2. pmc HEX expression and localization in normal mammary gland and breast carcinoma
    Cinzia Puppin
    Dipartimento di Scienze e Tecnologie Biomediche, Universita di Udine, Italy
    BMC Cancer 6:192. 2006
    ..Aim of the present study was to evaluate the localization and the function of the protein HEX in normal and tumoral breast tissues and in breast cancer cell lines...
  3. ncbi Expression of Pax-8, p53 and bcl-2 in human benign and malignant thyroid diseases
    F Puglisi
    Institute of Clinical Oncology, University of Udine, Italy
    Anticancer Res 20:311-6. 2000
    ..Immunohistochemical expression of the transcription factor Pax-8 in human thyroid diseases has never been investigated. The relationship between Pax-8, bcl-2 and p53 in thyroid neoplasms is also matter of interest...
  4. ncbi Prognostic significance of Ape1/ref-1 subcellular localization in non-small cell lung carcinomas
    F Puglisi
    University of Udine, Italy
    Anticancer Res 21:4041-9. 2001
    ..To evaluate the prognostic value of the DNA repair/redox-protein Ape1/ref-1 in a retrospective series of consecutive non-small cell lung carcinomas (NSCLC)...
  5. ncbi Role of mammography, ultrasound and large core biopsy in the diagnostic evaluation of papillary breast lesions
    Fabio Puglisi
    Clinical Oncology, Breast Unit, Breast Unit, University of Udine, Udine, Italy
    Oncology 65:311-5. 2003
    ..To prospectively evaluate the potential role of mammography, ultrasound and image-guided core biopsy in the diagnosis of papillary lesions of the breast...
  6. ncbi Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas
    Fabio Puglisi
    Clinica Oncologica, Policlinico Universitario, Piazzale S M Misericordia I 33100 Udine, Italy
    Oncol Rep 9:11-7. 2002
    ..014) and Cox proportional hazard model analysis identified APE/Ref-1 as an independent prognostic factor. The results suggest that subcellular localisation of APE/Ref-1 may influence the aggressiveness of breast carcinomas...
  7. ncbi Galectin-3 expression in non-small cell lung carcinoma
    Fabio Puglisi
    Clinical Oncology, University of Udine, Italy
    Cancer Lett 212:233-9. 2004
    ..In the present study, concomitant expression of nuclear galectin-3 and TTF-1 was independently associated with a worse clinical outcome (HR 2.0; P = 0.01)...
  8. ncbi Tumor shrinkage evaluation during and after preoperative doxorubicin and cyclophosphamide followed by docetaxel in patients with breast cancer
    Fabio Puglisi
    Clinical Oncology, Breast Unit, University of Udine, Udine, Italy
    Anticancer Res 24:2487-93. 2004
    ....
  9. ncbi Combined analysis of MIB-1 and thyroid transcription factor-1 predicts survival in non-small cell lung carcinomas
    F Puglisi
    Department of Clinical Oncology, University of Udine, Piazzale SM Misericordia, 33100, Udine, Italy
    Cancer Lett 162:97-103. 2001
    ..002), MIB-1 (P=0.01) and pStage (P=0.04). Accordingly, analysing TTF-1 and MIB-1 together, a better prediction of survival was obtained (P=0.02), with the poorest prognosis for the 'TTF-1++/MIB-1+' cases...
  10. ncbi Baseline staging tests after a new diagnosis of breast cancer: further evidence of their limited indications
    F Puglisi
    Breast Unit and Clinical Oncology, University of Udine, Piazzale SM Misericordia, 33100 Udine, Italy
    Ann Oncol 16:263-6. 2005
    ..However, in the absence of symptomatic disease, the usefulness of this routine diagnostic work-up is not evidence-based...
  11. ncbi Highlights from the 42nd annual meeting of the American Society of Clinical Oncology Atlanta, GA, USA, 2-6 June 2006
    Fabio Puglisi
    Azienda Ospedaliero Universitaria di Udine, Dipartimento di Oncologia, Piazzale S M Misericordia 15, I 33100, Udine, Italy
    Expert Opin Pharmacother 7:2309-18. 2006
    ..In addition, selected Phase I and II studies on promising novel therapeutic agents were briefly described. Finally, a 'question and answer' format was adopted to report results of interesting studies on some hot topics...
  12. ncbi Anthracyclines and taxanes induce the upregulation of thymidine phosphorylase in breast cancer cells
    Fabio Puglisi
    Department of Oncology, University Hospital of Udine, Udine, Italy
    Anticancer Drugs 18:883-8. 2007
    ..Translational studies, specifically designed on the basis of this rationale, are eagerly waited...
  13. ncbi Balance between cell division and cell death as predictor of survival in patients with non-small-cell lung cancer
    Fabio Puglisi
    Clinical Oncology, DRMM, University of Udine, Udine, Italy
    Oncology 63:76-83. 2002
    ..To evaluate the prognostic value of the balance between apoptosis and proliferation in non-small-cell lung cancer (NSCLC)...
  14. ncbi Thymidine phosphorylase expression is associated with time to progression in patients receiving low-dose, docetaxel-modulated capecitabine for metastatic breast cancer
    F Puglisi
    Department of Clinical Oncology, University Hospital of Udine, Piazzale S M Misericordia, 33100 Udine, Italy
    Ann Oncol 19:1541-6. 2008
    ..Furthermore, we explored the relationship between TP tumor expression and benefit from this regimen...
  15. ncbi Thymidine phosphorylase expression and benefit from capecitabine in patients with advanced breast cancer
    C Andreetta
    Department of Oncology, University Hospital of Udine, Udine, Italy
    Ann Oncol 20:265-71. 2009
    ..The present study aimed at evaluating the potential relationship between TP expression and benefit from capecitabine in patients with metastatic breast cancer (BC)...
  16. ncbi Prognostic value of thyroid transcription factor-1 in primary, resected, non-small cell lung carcinoma
    F Puglisi
    Department of Medical and Morphological Researches, Institute of Anatomic Pathology, Udine, Italy
    Mod Pathol 12:318-24. 1999
    ..04). The results of this study suggest that immunoreactivity for TTF-1 in NSCLC closely relates to clinical outcome, especially in patients with SCC...
  17. ncbi Image-guided core breast biopsy: a suitable method for preoperative biological characterization of small (pT1) breast carcinomas
    F Puglisi
    Department of Medical and Morphological Research, School of Oncology, Faculty of Medicine, University of Udine, Italy
    Cancer Lett 133:223-9. 1998
    ..This study showed that image-guided core biopsy is a suitable method that can be used to reveal some characteristics of the tumor biology in a preoperative stage...
  18. ncbi Expression of periostin in human breast cancer
    F Puglisi
    Dipartimento di Oncologia, Azienda Ospedaliero Universitaria di Udine, Italy
    J Clin Pathol 61:494-8. 2008
    ..Periostin is a secreted adhesion protein, normally expressed in mesenchime-derived cells. Aberrant expression of the periostin gene in epithelial tumours seems to play a role in angiogenesis and metastases...
  19. ncbi Diagnostic accuracy of perforated compression grid approach for mammographically guided core needle biopsy of breast lesions
    F Puglisi
    Policlinico Universitario, University of Udine, Italy
    Cancer Lett 146:181-8. 1999
    ....
  20. ncbi Telepathology using Internet multimedia electronic mail: remote consultation on gastrointestinal pathology
    V Della Mea
    Department of Anatomic Pathology, University of Udine, Italy
    J Telemed Telecare 2:28-34. 1996
    ..79). In 11 cases (15%) there was a misdiagnosis. However, the results are encouraging and suggest that Internet electronic mail can be used successfully for remote consultation in pathology...
  21. ncbi [Papillary lesions of the breast: diagnostic imaging and contribution of percutaneous needle biopsy with 14G needle]
    M Bazzocchi
    Istituto di Radiologia, , Udine, Italy
    Radiol Med 101:424-31. 2001
    ..The framing of benign and malignant PLB with imaging and core-biopsy was useful because the frequent association of benign PLB with concurrent or subsequent breast carcinoma suggests surgical excision and radiological follow-up...
  22. ncbi Lack of correlation between immunohistochemical expression of E2F-1, thymidylate synthase expression and clinical response to 5-fluorouracil in advanced colorectal cancer
    O Belvedere
    Division of Medical Oncology, University of Udine, P le S M Misericordia, Udine, Italy
    Ann Oncol 15:55-8. 2004
    ..E2F-1 is a transcription factor regulating the expression of TS along with other crucial DNA synthesis related enzymes...
  23. ncbi Stereotactic vacuum-assisted breast biopsy: results, follow-up and correlation with radiological suspicion
    C Zuiani
    Istituto di Radiologia, Universita Degli Studi di Udine, Via Colugna 50, I 33100, Udine, Italy
    Radiol Med 112:304-17. 2007
    ..The purpose of this study was to assess the accuracy and clinical usefulness of stereotactic vacuum-assisted biopsy (VAB) for diagnosing suspicious, nonpalpable, only mammographically detectable breast lesions...
  24. ncbi Role of pre-surgical breast MRI in the management of invasive breast carcinoma
    Chiara Del Frate
    Institute of Radiology, University of Udine, P le Santa Maria della Misericordia, 33100 Udine, Italy
    Breast 16:469-81. 2007
    ..8%. In conclusion, breast MRI determines a significant change in the management of patients affected by invasive breast carcinoma, particularly in patients eligible for conservative surgery after standard breast examination...
  25. doi Risk factors and survival outcomes in patients with brain metastases from breast cancer
    A M Minisini
    Department of Oncology, University Hospital of Udine, Piazzale S M Misericordia, 33100, Udine, Italy
    Clin Exp Metastasis 30:951-6. 2013
    ..Survival from diagnosis of CNS metastases was longer in patients with HER2-positive BC, while it was shorter in patients that did not receive any locoregional treatment, or with extra-CNS disease, or with more than 3 CNS lesions...
  26. ncbi Fatigue: a main component of anemia symptomatology
    A Sobrero
    Department of Medical Oncology, University of Udine, Italy
    Semin Oncol 28:15-8. 2001
    ..Accordingly, the search for new simplified methods of assessment of fatigue and other anemia-related symptoms and their treatment outcomes should be strongly encouraged...
  27. ncbi [Diagnostic imaging of lobular carcinoma of the breast: mammographic, ultrasonographic and MR findings]
    M Bazzocchi
    Istituto di Radiologia, Universita degli Studi, Udine
    Radiol Med 100:436-43. 2000
    ..To evaluate the most frequent mammographic, US and MR findings of invasive lobular carcinoma and the role of MRI in defining multifocality and/or multicentricity of this tumor histotype...
  28. ncbi [The Internet for medical research]
    V Della Mea
    Cattedra di Anatomia Patologica, Universita di Udine
    Pathologica 87:485-91. 1995
    ..In addition, as biomedical informations are also available on Internet, it becomes an important and irreplaceable resource on physician's desk...
  29. ncbi Locally advanced breast cancer: comparison of mammography, sonography and MR imaging in evaluation of residual disease in women receiving neoadjuvant chemotherapy
    Viviana Londero
    Institute of Radiology, University of Udine, Via Colugna 50, 33100 Udine, Italy
    Eur Radiol 14:1371-9. 2004
    ..5%. MRI assesses response to neoadjuvant chemotherapy better than traditional methods of physical examination and mammography...
  30. ncbi Proliferative high-risk lesions of the breast: contribution and limits of US-guided core biopsy
    Chiara Zuiani
    Istituto di Radiologia, Azienda Policlinico Universitario a Gestione Diretta, Dipartimento Interaziendale di Oncologia, Azienda Ospedaliera Santa Maria della Misericordia, Universita Degli Studi di Udine, Udine, Italy
    Radiol Med 110:589-602. 2005
    ..To discuss the management of the patient after a core biopsy diagnosis of high-risk proliferative breast lesion...
  31. ncbi Feasibility study of a web application for self-report of anticancer treatment toxicities
    Vincenzo Della Mea
    Department of Mathematics and Computer Science, University of Udine, 33100 Udine, Italy
    Stud Health Technol Inform 150:562-6. 2009
    ..The present paper describes a web application called PaTOS for self-report of anticancer therapy toxicities, and its evaluation in a preliminary interface analysis and then in a feasibility study...
  32. doi Pegylated liposomal doxorubicin in elderly patients with metastatic breast cancer
    Alessandro M Minisini
    University and General Hospital of Udine, Department of Oncology, Udine, Italy
    Expert Rev Anticancer Ther 8:331-42. 2008
    ..Tolerability of this agent in elderly patients has been confirmed by clinical trials in the advanced disease. Due to its efficacy and safety profile, PLD is an appealing treatment option for elderly breast cancer patients...
  33. doi From the podium to the patient: bringing the 2008 ASCO meeting to the clinic
    Giuseppe Aprile
    Department of Oncology, University Hospital of Udine, Udine, Italy
    Anticancer Drugs 19:941-56. 2008
    ....
  34. ncbi Determinants of recovery from amenorrhea in premenopausal breast cancer patients receiving adjuvant chemotherapy in the taxane era
    Alessandro Marco Minisini
    Department of Medical Oncology, University Hospital of Udine, Udine, Italy
    Anticancer Drugs 20:503-7. 2009
    ..04) were associated with an increased probability of permanent chemotherapy-induced amenorrhea. Recovery of menses after chemotherapy-induced amenorrhea occurs more probably in younger women, with no pregnancies and receiving taxanes...
  35. doi Pharmacology and therapeutic efficacy of capecitabine: focus on breast and colorectal cancer
    Giuseppe Aprile
    Department of Oncology, University Hospital of Udine, Italy
    Anticancer Drugs 20:217-29. 2009
    ....
  36. ncbi Expert pathology consultation through the Internet: melanoma versus benign melanocytic tumours
    V Della Mea
    Department of Pathology, University of Udine, Italy
    J Telemed Telecare 3:17-9. 1997
    ..002). This preliminary study suggest that telepathology by internet electronic mail can be a valuable tool for remote consultation in dematopathology, as well as for other diagnostic fields where expert consultation is necessary...
  37. ncbi Taxane-induced nail changes: incidence, clinical presentation and outcome
    A M Minisini
    Clinical Oncology, University of Udine, Udine, Italy
    Ann Oncol 14:333-7. 2003
    ..They include nail pigmentation, subungual hematoma, Beau's lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0% to 44%) is reviewed from a Medline search of the literature...
  38. ncbi Expression and localization of the homeodomain-containing protein HEX in human thyroid tumors
    Angela V D'Elia
    Dipartimento di Scienze e Tecnologie Biomediche, Universita di Udine, 33100 Udine, Italy
    J Clin Endocrinol Metab 87:1376-83. 2002
    ..These findings suggest that regulation of HEX entry in the nucleus of thyrocytes may represent a critical step during human thyroid tumorigenesis...
  39. ncbi Sonographic criteria for differentiation of benign and malignant solid breast lesions: size is of value
    C del Frate
    Istituto di Radiologia, Policlinico Universitario di Udine, Via Colugna 50, I 33100, Udine, Italy
    Radiol Med 111:783-96. 2006
    ..The purpose of this study was to evaluate whether lesion size may influence the value of sonographic findings in the differential diagnosis between benign or malignant breast lesions...
  40. ncbi Markers of the uPA system and common prognostic factors in breast cancer
    Alessandro Marco Minisini
    Department of Medical Oncology, University of Udine, Udine, Italy
    Am J Clin Pathol 128:112-7. 2007
    ..05). A direct correlation was seen between uPA and PAI-1, uPA and COX-2, and PAI-1 and COX-2 expression ( P < .05). Interaction between uPA and COX-2 systems in breast cancer deserves further study...
  41. ncbi PTEN and Egr-1 expression in thyroid proliferative lesions
    Carla Di Loreto
    Anatomic Pathology, University of Udine, Udine, Italy
    Cancer Lett 224:105-9. 2005
    ..75%), nodular hyperplasia (30.5%) and papillary carcinoma (28.25%). Adenomas, follicular carcinomas and undifferentiated carcinomas showed a significant decrease of nuclear positivity (P=0.001; P=0.001 and P=0.004, respectively)...
  42. doi Cognitive functions and elderly cancer patients receiving anticancer treatment: a prospective study
    Alessandro M Minisini
    Department of Oncology, University Hospital of Udine, Ple SM della Misercordia, 33100 Udine, Italy
    Crit Rev Oncol Hematol 67:71-9. 2008
    ..Overall, cognitive function did not worsen across time in each group. However, more patients in the CT group showed worsening in memory skills, and more patients in the ET and CT group experienced reduction in the attention score...
  43. doi Effect of age on hemoglobin levels and quality of life following treatment with epoetin alfa in cancer patients
    Fabio Puglisi
    Department of Oncology, University Hospital, Piazzale Santa Maria della Misericordia, Udine, Italy
    Crit Rev Oncol Hematol 69:175-82. 2009
    ..Thus, once-weekly epoetin alfa was equally effective in treating chemotherapy-related anemia in elderly and younger adult patients, with similar tolerability...
  44. ncbi BRCA2 germline mutations in primary cancer of the fallopian tube
    Sara Casarsa
    Clinica Ostetrica e Ginecologica, Università di Udine and Breast Unit, Policlinico Universitario di Udine, Udine, Italy
    Oncol Rep 12:313-6. 2004
    ....
  45. ncbi What is the effect of systemic anticancer treatment on cognitive function?
    Alessandro Minisini
    Unit of Medical Oncology, University of Udine, Italy
    Lancet Oncol 5:273-82. 2004
    ..These trials should have sufficient statistical power and, importantly, should also be prospective...
  46. ncbi Topoisomerase IIalpha and APE/ref-1 are associated with pathologic response to primary anthracycline-based chemotherapy for breast cancer
    Alessandro M Minisini
    Medical Oncology Department, University of Udine and S Maria della Misericordia Hospital, P le SM della Misericordia, I 33100 Udine, Italy
    Cancer Lett 224:133-9. 2005
    ..Higher topoisomerase IIalpha (P=0.007) and lower APE/ref-1 (P=0.04) expression were associated with better pathologic response...
  47. ncbi Phase II, randomized trial of preoperative epirubicin-paclitaxel +/- gefitinib with biomarker evaluation in operable breast cancer
    Valentina Guarneri
    Department of Oncology and Hematology, Modena University Hospital, Via del Pozzo 71, 41100 Modena, Italy
    Breast Cancer Res Treat 110:127-34. 2008
    ..Secondary aims: to evaluate EGFR, (p)-EGFR, Ki67, apoptotic index (TUNEL test) and VEGFR2 expression from baseline to surgery, percentage of pathologic complete response (pCR), and toxicity...
  48. ncbi Progress and new standards of care in the management of HER-2 positive breast cancer
    Gaston Demonty
    Medical Oncology Clinic, Jules Bordet Institute, Brussels, Belgium
    Eur J Cancer 43:497-509. 2007
    ..The results of the recently reported adjuvant trials are commented, as the positive results of these trials changed the standard of care for patients with this particular type of breast cancer...
  49. ncbi Sequential chemotherapy with paclitaxel plus cisplatin, followed by vinorelbine, followed by gemcitabine in advanced non-small cell lung cancer: an Alpe-Adria Thoracic Oncology Multidisciplinary group study (ATOM 001)
    Francesco Grossi
    Disease Management Team Lung Cancer, Medical Oncology A, National Institute for Cancer Research, Largo R Benzi 10, 16132 Genoa, Italy
    Lung Cancer 46:99-106. 2004
    ..This pilot experience provides the basis for an ongoing randomized phase III trial comparing our sequential regimen versus cisplatin plus gemcitabine...
  50. ncbi Shrinking the tumor, shrinking the patient sample size: the early disclosure dilemma
    Fabio Puglisi
    J Clin Oncol 23:6803-4; author reply 6804-5. 2005
  51. ncbi Proteomic evaluation of core biopsy specimens from breast lesions
    Alessia Bisca
    Dipartimento di Scienze e Tecnologie Biomediche, Centro M A T I, Universita di Udine, Piazzale Kolbe 1, Udine 33100, Italy
    Cancer Lett 204:79-86. 2004
    ..Thus, our study provides a methodology to perform proteomic analysis on pre-operative samples of breast lesions...
  52. pmc Bone scanning in lung cancer: pretest probability is of value
    Fabio Puglisi
    BMJ 329:231. 2004
  53. ncbi D-dimer and venous thromboembolism
    Fabio Puglisi
    Ann Intern Med 141:482-3; author reply 483. 2004
  54. ncbi Trastuzumab and breast cancer. Are we just beyond the prologue of a fascinating story?
    Fabio Puglisi
    Onkologie 28:547-9. 2005