Maurizio Prato

Summary

Affiliation: University of Trieste
Country: Italy

Publications

  1. ncbi Production of large graphene sheets by exfoliation of graphite under high power ultrasound in the presence of tiopronin
    Mildred Quintana
    CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 48:12159-61. 2012
  2. ncbi Functionalized carbon nanotubes in drug design and discovery
    Maurizio Prato
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, 34127 Trieste, Italy
    Acc Chem Res 41:60-8. 2008
  3. ncbi Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells
    Hélène Dumortier
    CNRS UPR 9021, Institute of Molecular and Cellular Biology, Strasbourg, France
    Nano Lett 6:1522-8. 2006
  4. ncbi Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
    Claudia Cusan
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, I-34127, Trieste, Italy
    Farmaco 60:327-32. 2005
  5. ncbi Tuning electron transfer through translational motion in molecular shuttles
    Aurelio Mateo-Alonso
    Italian Interuniversity Consortium on Materials, Science, and Technology (INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 46:3521-5. 2007
  6. ncbi Multiple hydrogen bond interactions in the processing of functionalized multi-walled carbon nanotubes
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 6:23-31. 2012
  7. ncbi Synthesis, characterization, and photoinduced electron transfer in functionalized single wall carbon nanohorns
    Carla Cioffi
    INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    J Am Chem Soc 129:3938-45. 2007
  8. ncbi Two-dimensional diffusion-ordered NMR spectroscopy as a tool for monitoring functionalized carbon nanotube purification and composition
    Riccardo Marega
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    ACS Nano 4:2051-8. 2010
  9. ncbi Photophysical and electrochemical properties of a fullerene-stoppered rotaxane
    Aurelio Mateo-Alonso
    INSTM, Unit of Trieste and Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Photochem Photobiol Sci 5:1173-6. 2006
  10. ncbi Spinal cord explants use carbon nanotube interfaces to enhance neurite outgrowth and to fortify synaptic inputs
    Alessandra Fabbro
    Life Science Department, Center for Neuroscience B R A I N, University of Trieste, Via Giorgieri 1, I 34127 Trieste, Italy
    ACS Nano 6:2041-55. 2012

Collaborators

Detail Information

Publications97

  1. ncbi Production of large graphene sheets by exfoliation of graphite under high power ultrasound in the presence of tiopronin
    Mildred Quintana
    CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 48:12159-61. 2012
    ..Under ultrasonication, the production of high quality graphene layers by exfoliation of graphite was achieved via addition of tiopronin as an antioxidant...
  2. ncbi Functionalized carbon nanotubes in drug design and discovery
    Maurizio Prato
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, 34127 Trieste, Italy
    Acc Chem Res 41:60-8. 2008
    ....
  3. ncbi Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells
    Hélène Dumortier
    CNRS UPR 9021, Institute of Molecular and Cellular Biology, Strasbourg, France
    Nano Lett 6:1522-8. 2006
    ..f-CNT 3, which instead possesses reduced solubility and forms mainly stable water suspensions, preserved lymphocytes' functionality while provoking secretion of proinflammatory cytokines by macrophages...
  4. ncbi Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
    Claudia Cusan
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, I-34127, Trieste, Italy
    Farmaco 60:327-32. 2005
    ....
  5. ncbi Tuning electron transfer through translational motion in molecular shuttles
    Aurelio Mateo-Alonso
    Italian Interuniversity Consortium on Materials, Science, and Technology (INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 46:3521-5. 2007
  6. ncbi Multiple hydrogen bond interactions in the processing of functionalized multi-walled carbon nanotubes
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 6:23-31. 2012
    ..These results open new possibilities toward the controlled manipulation of CNTs on surfaces, using H-bonding self-assembly as the main driving force...
  7. ncbi Synthesis, characterization, and photoinduced electron transfer in functionalized single wall carbon nanohorns
    Carla Cioffi
    INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    J Am Chem Soc 129:3938-45. 2007
    ..Transient absorption spectra permitted the electron-transfer process between the porphyrins and the carbon nanostructures to be highlighted...
  8. ncbi Two-dimensional diffusion-ordered NMR spectroscopy as a tool for monitoring functionalized carbon nanotube purification and composition
    Riccardo Marega
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    ACS Nano 4:2051-8. 2010
    ..Complete elimination of physisorbed polyethylene glycol was achieved using diafiltration...
  9. ncbi Photophysical and electrochemical properties of a fullerene-stoppered rotaxane
    Aurelio Mateo-Alonso
    INSTM, Unit of Trieste and Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Photochem Photobiol Sci 5:1173-6. 2006
    ..The results evidenced the strong binding interactions between the template and the macrocycle, which are also supported by molecular modelling...
  10. ncbi Spinal cord explants use carbon nanotube interfaces to enhance neurite outgrowth and to fortify synaptic inputs
    Alessandra Fabbro
    Life Science Department, Center for Neuroscience B R A I N, University of Trieste, Via Giorgieri 1, I 34127 Trieste, Italy
    ACS Nano 6:2041-55. 2012
    ..On the other hand, exploring spontaneous and evoked synaptic activity unmasks an increase in synaptic efficacy in neurons located at as far as 5 cell layers from the cell-substrate interactions...
  11. ncbi Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts
    Giada Cellot
    Life Science Department, B R A I N, University of Trieste, Via Fleming 22, I 34127, Trieste, Italy
    Nat Nanotechnol 4:126-33. 2009
    ..These considerations offer a perspective that would allow us to predict or engineer interactions between neurons and carbon nanotubes...
  12. ncbi Synthesis and characterization of a carbon nanotube-dendron series for efficient siRNA delivery
    M Antonia Herrero
    Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 131:9843-8. 2009
    ..The work reported here highlights the fact that dendron-functionalized CNTs can be rationally designed as efficient carriers of siRNA that can eventually lead to gene silencing...
  13. ncbi Microwave-induced multiple functionalization of carbon nanotubes
    Fulvio G Brunetti
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 130:8094-100. 2008
    ..The doubly functionalized SWNTs can be considered potentially useful for many interesting applications...
  14. ncbi Charge transfer reactions along a supramolecular redox gradient
    Aurelio Mateo-Alonso
    Center of Excellence for Nanostructured Materials, Italian Interuniversity Consortium on Materials Science and Technology, Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Italy
    J Am Chem Soc 130:14938-9. 2008
    ..A rotaxane scaffold is used to align three photo/electroactive units along a supramolecular redox gradient leading to a cascade of through-space charge transfer reactions...
  15. ncbi Synthesis and characterization of highly water-soluble dendrofulleropyrrolidine bisadducts with DNA binding activity
    Alejandro Montellano López
    Center of Excellence for Nanostructured Materials CENMAT, Department of Chemical and Pharmaceutical Sciences, and INSTM, Unit of Trieste, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Org Lett 14:4450-3. 2012
    ..Electrophoresis studies show different DNA binding efficiencies for different adducts, some of which can be considered excellent candidates for DNA binding therapies...
  16. ncbi Carbon nanotube scaffolds tune synaptic strength in cultured neural circuits: novel frontiers in nanomaterial-tissue interactions
    Giada Cellot
    Life Science Department, B R A I N, University of Trieste, I 34127 Trieste, Italy
    J Neurosci 31:12945-53. 2011
    ..Using electrophysiological recordings and rat cultured neural networks, we describe the ability of a nanoscaled material to promote the formation of synaptic contacts and to modulate their plasticity...
  17. ncbi Design and activity of cationic fullerene derivatives as inhibitors of acetylcholinesterase
    Giorgia Pastorin
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, Strasbourg, France
    Org Biomol Chem 4:2556-62. 2006
    ..The cationic C(60) derivatives used in this study represent a new class of molecules potentially able to modulate the enzymatic activity of acetylcholinesterase...
  18. ncbi Formation of efficient catalytic silver nanoparticles on carbon nanotubes by adenine functionalization
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg, France
    Angew Chem Int Ed Engl 50:9893-7. 2011
    ..The catalytic efficiency of the resulting species was assessed in the oxidation of 2-methylhydroquinone to its corresponding benzoquinone, with complete recovery and without loss of activity of the catalyst...
  19. ncbi Functionalization of graphene via 1,3-dipolar cycloaddition
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    ACS Nano 4:3527-33. 2010
    ....
  20. ncbi A simple road for the transformation of few-layer graphene into MWNTs
    Mildred Quintana
    Center of Excellence for Nanostructured Materials and INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    J Am Chem Soc 134:13310-5. 2012
    ..This new methodology matches the long held notion that CNTs are rolled up graphene layers. The proposed mechanism is general and will lead to control the production of carbon nanostructures by simple ultrasonication treatments...
  21. ncbi Solid-phase synthesis and characterization of a novel fullerene-peptide derived from histone H3
    Alberto Bianco
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France
    Org Biomol Chem 1:4141-3. 2003
    ..By molecular modelling it was verified that this peptide derivative is able to retain a binding capacity to the MHC (major histocompatibility complex) molecule similar to that of the cognate epitope...
  22. ncbi Carbon nanotubes: on the road to deliver
    Alberto Bianco
    UPR 9021, CNRS, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, F 67084, Strasbourg, France
    Curr Drug Deliv 2:253-9. 2005
    ..This opens new therapeutic and preventive opportunities to combat diseases. The scope of this review is to summarize our recent work in this rapidly growing field...
  23. ncbi Engineering of supramolecular H-bonded nanopolygons via self-assembly of programmed molecular modules
    Anna Llanes-Pallas
    Universita degli Studi di Trieste, Dipartimento di Scienze Farmaceutiche and INSTM UdR di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 131:509-20. 2009
    ....
  24. ncbi Dispersion of single-walled carbon nanotubes with an extended diazapentacene derivative
    Aurelio Mateo-Alonso
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche, INSTM UdR di Trieste, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Phys Chem A 111:12669-73. 2007
    ..This approach is very attractive for manipulation of SWCNTs for electronic applications...
  25. ncbi Synthesis and biological properties of fullerene-containing amino acids and peptides
    Davide Pantarotto
    Dipartimento di Scienze Farmaceutiche, , Italy
    Mini Rev Med Chem 4:805-14. 2004
    ..Finally, applications in medicinal chemistry of such types of amino acids and peptides will be highlighted...
  26. ncbi Applications of carbon nanotubes in drug delivery
    Alberto Bianco
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France
    Curr Opin Chem Biol 9:674-9. 2005
    ..Because functionalised CNT display low toxicity and are not immunogenic, such systems hold great potential in the field of nanobiotechnology and nanomedicine...
  27. ncbi Diffusion-ordered NMR spectroscopy in the structural characterization of functionalized carbon nanotubes
    Riccardo Marega
    Center of Excellence for Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 131:9086-93. 2009
    ..The overall results show that the diffusion-based NMR spectroscopy is a fast and promising approach for the characterization of covalently modified CNT derivatives...
  28. ncbi A dendritic fullerene-porphyrin dyad
    Stephane Campidelli
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Photochem Photobiol Sci 5:1137-41. 2006
    ..Femto- and picosecond transient absorption permit to identify the formation of a radical ion pair while nanosecond experiments allowed the determination of the charge recombination lifetimes...
  29. ncbi Organic functionalisation and characterisation of single-walled carbon nanotubes
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, 15 rue Rene Descartes, 67000, Strasbourg, France
    Chem Soc Rev 38:2214-30. 2009
    ..In this tutorial review, we survey the covalent modification of SWCNTs with organic moieties, and illustrate the major analytical techniques routinely used to characterise the functionalised materials...
  30. ncbi Fullerene C₆₀ as a multifunctional system for drug and gene delivery
    Alejandro Montellano
    Center of Excellence for Nanostructured Materials CENMAT, Department of Chemical and Pharmaceutical Sciences, and INSTM, Unit of Trieste University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Nanoscale 3:4035-41. 2011
    ..Promising results have emerged in the last years, bringing fullerenes again to the front of interest. Herein, the state of the art of this emerging field is presented and illustrated with some of the most representative examples...
  31. ncbi Light-induced selective deposition of Au nanoparticles on single-wall carbon nanotubes
    Mildred Quintana
    Center of Excellence on Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Università degli Studi di Trieste, Piazzale Europa 1, I 34127, Trieste, Italia
    ACS Nano 4:6105-13. 2010
    ..This new technique can be useful for the preparation of nanohybrid composites with enhanced properties, as increased thermal stability, and to obtain purified SWNT...
  32. ncbi [60]fullerene-pyrrolidine-N-oxides
    Peter Brough
    Dipartimento di Scienze Farmaceutiche, , 34127 Trieste, Italy
    J Org Chem 71:2014-20. 2006
    ..Preliminary details of the effects of substitution on the reactivity of the pyrrolidine ring are also reported...
  33. ncbi Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits
    Andrea Mazzatenta
    Physiology and Pathology Department, B R A I N, University of Trieste, I 34127, Trieste, Italy
    J Neurosci 27:6931-6. 2007
    ..Our experimental results, supported by mathematical models to describe the electrical interactions occurring in SWNT-neuron hybrid systems, clearly indicate that SWNTs can directly stimulate brain circuit activity...
  34. ncbi Selective organic functionalization of graphene bulk or graphene edges
    Mildred Quintana
    Center of Excellence for Nanostructured Materials CENMAT, INSTM UdR di Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, University of Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 47:9330-2. 2011
    ..Graphene sheets have been functionalized with a PAMAM dendron, finding that graphene can be efficiently functionalized all over the surface, or only at the edges, depending on the reactions used in the functionalization process...
  35. ncbi Hemolytic effects of water-soluble fullerene derivatives
    Susanna Bosi
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa, 1-34127 Trieste, Italy
    J Med Chem 47:6711-5. 2004
    ..A validation of these experimental observations has been performed by theoretical studies in which hydrophilic and hydrophobic surface areas were correlated quantitatively with hemolytic properties...
  36. ncbi Carbon nanotube-nucleobase hybrids: nanorings from uracil-modified single-walled carbon nanotubes
    Prabhpreet Singh
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg, France
    Chemistry 17:6772-80. 2011
    ..These nanorings can be envisaged for the development of advanced electronic circuits...
  37. ncbi Anti-HIV properties of cationic fullerene derivatives
    Silvia Marchesan
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, I-34127 Trieste, Italy
    Bioorg Med Chem Lett 15:3615-8. 2005
    ..None of the compounds showed any inhibitory activity against a variety of DNA and RNA viruses other than HIV...
  38. ncbi Carbon nanotube substrates boost neuronal electrical signaling
    Viviana Lovat
    Dipartimento di Scienze Farmaceutiche, Piazzale Europa 1, Trieste, Italy
    Nano Lett 5:1107-10. 2005
    ..The increase in the efficacy of neural signal transmission may be related to the specific properties of CNT materials, such as the high electrical conductivity...
  39. ncbi Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics
    Cedric Klumpp
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 15 rue Rene Descartes, 67084 Strasbourg, France
    Biochim Biophys Acta 1758:404-12. 2006
    ..Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules...
  40. ncbi Interfacing neurons with carbon nanotubes: (re)engineering neuronal signaling
    Alessandra Fabbro
    Life Science Department, Center for Neuroscience B R A I N, University of Trieste, TS, Italy
    Prog Brain Res 194:241-52. 2011
    ..Therefore, it is particularly relevant to improve our knowledge on the impact on neuronal performance of interfacing nerve cells with CNTs...
  41. ncbi Targeting carbon nanotubes against cancer
    Chiara Fabbro
    Center of Excellence for Nanostructured Materials, INSTM unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, Universita di Trieste, Trieste, 34127, Italy
    Chem Commun (Camb) 48:3911-26. 2012
    ..The attention throughout the review is focused on the different targeting strategies proposed so far, mainly based on antibodies, but also on other specifically recognised molecules or on the application of an external magnetic field...
  42. ncbi Functionalized carbon nanotubes for plasmid DNA gene delivery
    Davide Pantarotto
    Dipartimento di Scienze Farmaceutiche, , 34127 Trieste, Italy
    Angew Chem Int Ed Engl 43:5242-6. 2004
  43. ncbi Synthesis and anti-HIV properties of new water-soluble bis-functionalized[60]fullerene derivatives
    Susanna Bosi
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, I-34127 Trieste, Italy
    Bioorg Med Chem Lett 13:4437-40. 2003
    ..The presence of a quaternary pyrrolidinium nitrogen is essential to increase solubility...
  44. ncbi Efficient water oxidation at carbon nanotube-polyoxometalate electrocatalytic interfaces
    Francesca M Toma
    Center of Excellence for Nanostructured Materials CENMAT, INSTM, Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Nat Chem 2:826-31. 2010
    ..Our bioinspired electrode addresses the one major challenge of artificial photosynthesis, namely efficient water oxidation, which brings us closer to being able to power the planet with carbon-free fuels...
  45. ncbi Antifungal activity of amphotericin B conjugated to carbon nanotubes
    Monica Benincasa
    Department of Life Sciences, University of Trieste, Italy
    ACS Nano 5:199-208. 2011
    ..Interestingly, the f-CNT-AMB 1 does not show any significant toxic effect on Jurkat cells at antifungal concentrations...
  46. ncbi Reversible microwave-assisted cycloaddition of aziridines to carbon nanotubes
    Fulvio G Brunetti
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 129:14580-1. 2007
    ..With our procedure, we easily scale-up the reaction up to 250 mg of functionalized MWNT in 1 h. We also provide an indirect proof of the covalent sidewall functionalization of the tubes...
  47. ncbi Synthesis, structural characterization, and immunological properties of carbon nanotubes functionalized with peptides
    Davide Pantarotto
    Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France
    J Am Chem Soc 125:6160-4. 2003
    ..In addition, this peptide-NT conjugate is immunogenic, eliciting antibody responses of the right specificity. Such a system could be greatly advantageous for diagnostic purposes and could find future applications in vaccine delivery...
  48. ncbi Making carbon nanotubes biocompatible and biodegradable
    Alberto Bianco
    CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d Immunologie et Chimie Thérapeutiques, Strasbourg, 67000, France
    Chem Commun (Camb) 47:10182-8. 2011
    ..This article highlights recent advances that can act as paradigm-shifts towards the design of biocompatible and biodegradable functionalised carbon nanotubes and allow their translation into the clinic...
  49. ncbi Fullerenes: multitask components in molecular machinery
    Aurelio Mateo-Alonso
    Dipartimento di Scienze Farmaceutiche and Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali INSTM, Unità di Trieste, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 46:8120-6. 2007
    ..Such molecular motion can be employed to modulate light-driven electron-transfer events, extending the potential applications of molecular machines to the typical fields of application of fullerenes...
  50. ncbi In vitro behavior of multifunctionalized fullerene-warfarin conjugates
    Marina Zacchigna
    Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Nanosci Nanotechnol 9:6210-21. 2009
    ..We have chosen warfarin as a model compound because it a widely used drug. We have analyzed the stability in vitro of the conjugates and found that the drug is released from the carbon support only after incubation in mouse plasma...
  51. ncbi Macromolecular properties of cepacian in water and in dimethylsulfoxide
    Yury Herasimenka
    Department of Biochemistry, Biophysics and Macromolecules Chemistry, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy
    Carbohydr Res 343:81-9. 2008
    ..These interactions were attributed to hydrogen bonding and contributed to structure rigidity...
  52. ncbi Oligonucleotides and oligonucleotide conjugates: a new approach for cancer treatment
    Tatiana Da Ros
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, I-34127 Trieste, Italy
    Curr Med Chem 12:71-88. 2005
    ....
  53. ncbi Efficient modulation of the third order nonlinear optical properties of fullerene derivatives
    Aurelio Mateo-Alonso
    Center of Excellence for Nanostructured Materials, Dipartimento di Scienze Farmaceutiche and Italian Interuniversity Consortium on Materials Science and Technology, Unit of Trieste, , Italy
    J Am Chem Soc 130:1534-5. 2008
  54. ncbi Liquid-crystalline bisadducts of [60]fullerene
    Stephane Campidelli
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Org Chem 71:7603-10. 2006
    ..Therefore, the bisadducts form monolayered smectic A phases. The title compounds are promising supramolecular materials as they combine the self-organizing behavior of liquid crystals with the properties of fullerene...
  55. ncbi Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes
    Valentina Martinelli
    International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
    Nano Lett 12:1831-8. 2012
    ..Furthermore, we observed changes in the electrophysiological properties of cardiomyocytes, suggesting that carbon nanotubes are able to promote cardiomyocyte maturation...
  56. ncbi Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
    Claudia Cusan
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, I-34127, Trieste, Italy
    Farmaco 60:7-13. 2005
    ..The absence of activity vs. human 5-LOX strongly suggests a re-consideration of phenidone and its analogs as 5-LOX inhibitors in humans...
  57. ncbi Reverse shuttling in a fullerene-stoppered rotaxane
    Aurelio Mateo-Alonso
    INSTM, Unit of Trieste, and Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    Org Lett 8:5173-6. 2006
    ..The reverse shuttling is confirmed by NMR spectroscopy and can be monitored by cyclic voltammetry. The electrochemically generated anions on the fullerene moiety are stabilized by the closer proximity of the macrocycle...
  58. ncbi Dendrimer-functionalized single-wall carbon nanotubes: synthesis, characterization, and photoinduced electron transfer
    Stephane Campidelli
    INSTM and Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 128:12544-52. 2006
    ..Complementary transient absorption measurements not only corroborate the fast decay of the photoexcited tetraphenylporphyrin but also confirm that intraconjugate charge separation evolves from the excited porphyrin to the SWNTs...
  59. ncbi Highly sensitive electrochemiluminescent nanobiosensor for the detection of palytoxin
    Valeria Anna Zamolo
    Center of Excellence on Nanostructured Materials, Department of Chemical and Pharmaceutical Sciences, and INSTM, Unit of Trieste, University of Trieste, P le Europa 1, 34127 Trieste, Italy
    ACS Nano 6:7989-97. 2012
    ..2 μg/kg of mussel meat) more than 2 orders of magnitude more sensitive than that of the commonly used detection techniques, such as LC-MS/MS...
  60. ncbi Multimode assembly of phenanthroline nanowires decorated with gold nanoparticles
    Marek Grzelczak
    Center of Excellence for Nanostructured Materials CENMAT and INSTM, Unit of Trieste, Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Trieste, Piazzale Europa 1, I 34127 Trieste, Italy
    Chem Commun (Camb) 46:9122-4. 2010
    ....
  61. ncbi Multiwalled carbon nanotubes drive the activity of metal@oxide core-shell catalysts in modular nanocomposites
    Matteo Cargnello
    Department of Chemical and Pharmaceutical Sciences, INSTM, Center of Excellence for Nanostructured Materials, University of Trieste, Via L Giorgieri 1, 34127 Trieste, Italy
    J Am Chem Soc 134:11760-6. 2012
    ..The modular approach shown here demonstrates that high-performance catalytic materials can be obtained through the precise organization of nanoscale building blocks...
  62. ncbi A carbon nano-onion-ferrocene donor-acceptor system: synthesis, characterization and properties
    Carla T Cioffi
    Center of Excellence on Nanostructured Materials CENMAT, Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, 34127 Trieste, Italy
    Chemistry 15:4419-27. 2009
    ..At high energy, emission comes from CNOs with smaller external shells and a higher degree of functionalization...
  63. ncbi Solid-phase synthesis of fullerene-peptides
    Davide Pantarotto
    Department of Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
    J Am Chem Soc 124:12543-9. 2002
    ..aureus and also lysed erythrocytes. The availability of a fullero-amino acid easily useable in the SPPS of fullero-peptides may thus open the way to the synthesis of new types of biologically active oligomers...
  64. ncbi Fullerene derivatives: an attractive tool for biological applications
    Susanna Bosi
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, 34127 Trieste, Italy
    Eur J Med Chem 38:913-23. 2003
    ..This action, together with the direct electron transfer from excited state of fullerene and DNA bases, can be used to cleave DNA. In this review we report the most recent aspects of fullerene biological applications...
  65. ncbi Trimodular engineering of linear supramolecular miniatures on Ag(111) surfaces controlled by complementary triple hydrogen bonds
    Anna Llanes-Pallas
    Dip. Scienze Farmaceutiche and INSTM UdR di Trieste, , Piazzale Europa 1, 34127 Trieste, Italy
    Angew Chem Int Ed Engl 47:7726-30. 2008
  66. ncbi Supramolecular self-assembled fullerene nanostructures
    Vasilios Georgakilas
    Dipartimento di Scienze Farmaceutiche, , Piazzale Europa 1, 34127 Trieste, Italy
    Proc Natl Acad Sci U S A 99:5075-80. 2002
    ..The efficient method to fabricate almost perfect and uniformly shaped nanotubular crystals, which order spontaneously by self-assembly, opens the way to the possibility of exploiting the fullerene properties at the nanometer scale...
  67. ncbi Microscopic and spectroscopic characterization of paintbrush-like single-walled carbon nanotubes
    Davide Bonifazi
    Dipartimento di Scienze Farmaceutiche and INSTM UdR Trieste, , Italy
    Nano Lett 6:1408-14. 2006
    ..Thermogravimetric analysis (TGA), steady-state electronic absorption (UV-vis-NIR), and Raman spectroscopic studies confirm the STM observations...
  68. ncbi Dispersable carbon nanotube/gold nanohybrids: evidence for strong electronic interactions
    G M Aminur Rahman
    University of Notre Dame, Radiation Laboratory, Notre Dame, IN 46556, USA
    Small 1:527-30. 2005
  69. ncbi Spectroscopic characterization of photolytically generated radical ion pairs in single-wall carbon nanotubes bearing surface-immobilized tetrathiafulvalenes
    M Angeles Herranz
    Departamento de Quimica Organica I, Facultad de Quimica, Universidad Complutense de Madrid, E 28040 Madrid, Spain
    J Am Chem Soc 130:66-73. 2008
    ..New conduction band electrons, injected from photoexcited exTTF, shift the transitions that are associated with the van Hove singularities to lower energies...
  70. ncbi Thermal stripping of supramolecular structures: C60 nanorods
    Michael Mannsberger
    , , A-1090 Wien, Strudlhofgasse 4, Austria
    J Nanosci Nanotechnol 5:198-203. 2005
    ..Synthesizing fullerenic polymers in this way can lead to several applications...
  71. ncbi Separation of metallic and semiconducting single-walled carbon nanotubes via covalent functionalization
    Stephane Campidelli
    Laboratoire d Electronique Moleculaire, CEA Saclay, 91191 Gif sur Yvette, France
    Small 3:1672-6. 2007
  72. ncbi Nonlinear optical properties of ferrocene- and porphyrin-[60]fullerene dyads
    Evangelia Xenogiannopoulou
    Institute of Chemical Engineering and High Temperature, Chemical Processes ICEHT, Foundation for Research and Technology Hellas FORTH, P O Box 1414, 26504 Patras, Greece
    Chemphyschem 8:1056-64. 2007
    ....
  73. ncbi Supramolecular hybrids of [60]fullerene and single-wall carbon nanotubes
    Dirk M Guldi
    Lehrstuhl für Physikalische Chemie I, Universitat Erlangen Nurnberg, Egerlandstr 3, 91058 Erlangen, Germany
    Chemistry 12:3975-83. 2006
    ....
  74. ncbi Functional single-wall carbon nanotube nanohybrids--associating SWNTs with water-soluble enzyme model systems
    Dirk M Guldi
    Institute for Physical and Theoretical Chemistry, Egerlandstrasse 3, 91058 Erlangen, Germany
    J Am Chem Soc 127:9830-8. 2005
    ..Particularly beneficial are charge recombination dynamics that are located deep in the Marcus-inverted region. We include, for the first time, work devoted to exploring and testing FeP(8)(+) and CoP(8)(+) in donor-acceptor nanohybrids...
  75. ncbi Ordering fullerene materials at nanometer dimensions
    Dirk M Guldi
    Institute for Physical and Theoretical Chemistry, Universitat Erlangen, 91058 Erlangen, Germany
    Acc Chem Res 38:38-43. 2005
    ....
  76. ncbi Novel hybrid materials consisting of regioregular poly(3-octylthiophene)s covalently attached to single-wall carbon nanotubes
    Andreas A Stefopoulos
    Department of Chemistry, University of Patras, Patras, Greece
    Chemistry 14:8715-24. 2008
    ..Moreover, studies of the properties of these materials have provided strong evidence for an electron transfer from the regioregular poly(3-octylthiophene) to the single-wall carbon nanotube...
  77. ncbi Singling out the electrochemistry of individual single-walled carbon nanotubes in solution
    Demis Paolucci
    INSTM, Unit of Bologna, Dipartimento di Chimica, Universita di Bologna, Via Selmi 2, I 40126 Bologna, Italy
    J Am Chem Soc 130:7393-9. 2008
    ....
  78. ncbi Electrostatic complexation and photoinduced electron transfer between Zn-cytochrome c and [olyanionic fullerene dendrimers
    Martin Braun
    , 91054 Erlangen, Germany
    Chemistry 9:3867-75. 2003
    ..These findings were also supported by circular dichroism as well as by extensive molecular dynamics (MD) simulations...
  79. ncbi Targeted delivery of amphotericin B to cells by using functionalized carbon nanotubes
    Wei Wu
    , UPR9021 CNRS, , 67084 Strasbourg, France
    Angew Chem Int Ed Engl 44:6358-62. 2005
  80. ncbi Multipurpose organically modified carbon nanotubes: from functionalization to nanotube composites
    Vasilios Georgakilas
    Institute of Materials Science, N C S R Demokritos, GR 15310 Agia Paraskevi Athens, Greece
    J Am Chem Soc 130:8733-40. 2008
    ..Additionally, the functionalized CNTs could easily be combined with polymers and layered aluminosilicate clay minerals to give homogeneous, coherent, transparent CNT thin films and gels...
  81. ncbi Covalent assembly and micropatterning of functionalized multiwalled carbon nanotubes to monolayer-modified Si(111) surfaces
    Bruno Fabre
    Université de Rennes 1 and CNRS UMR 6226 Sciences Chimiques de Rennes, Matiere Condensee et Systemes Electroactifs MaCSE, Campus de Beaulieu, 35042 Rennes Cedex, France
    Langmuir 24:6595-602. 2008
    ..In particular, it is demonstrated that the MWNT patterns allow a faster charge transfer which is consistent with the results obtained for the uniformly modified surfaces...
  82. ncbi Carbon nanotubes as nanomedicines: from toxicology to pharmacology
    Lara Lacerda
    Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London 29-39 Brunswick Square WC1N 1AX, United Kingdom
    Adv Drug Deliv Rev 58:1460-70. 2006
    ....
  83. ncbi Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties
    Alberto Bianco
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France
    J Am Chem Soc 127:58-9. 2005
    ..Functionalized cationic carbon nanotubes are able to form a stable complex with CpG ODN based on charge interaction and to increase the immunostimulatory activity of CpG motifs...
  84. ncbi Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors
    Arianna Gugliucci
    Venetian Institute of Molecular Medicine, I-35129 Padova, Italy
    J Biol Chem 277:31789-95. 2002
    ..This approach should be specifically useful to kill cells possessing a high flux of arachidonic acid and its metabolites like prostate and colon cancer cells...
  85. ncbi Clay-fulleropyrrolidine nanocomposites
    Dimitrios Gournis
    Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece
    J Am Chem Soc 128:6154-63. 2006
    ..The reported composite materials constitute a new hybrid system, where C(60) differs from its crystals or its solutions, and open new perspectives for the design and construction of novel C(60)-based organic/clay hybrid materials...
  86. ncbi Interactions in single wall carbon nanotubes/pyrene/porphyrin nanohybrids
    Christian Ehli
    Institute for Physical and Theoretical Chemistry, Egerlandstrasse 3, 91058 Erlangen, Germany
    J Am Chem Soc 128:11222-31. 2006
    ..This formation is fully rationalized on the basis of the properties of the individual moieties. Additional modeling shows that the data are likely to be relevant to the SWNTs present in the sample, which possess wider diameters...
  87. ncbi Growth and characterization of films containing fullerenes and water soluble porphyrins for solar energy conversion applications
    Vito Sgobba
    The Institute for Physical Chemistry, Friedrich Alexander Universitat, Erlangen Nurnberg, 91058 Erlangen, Germany
    J Am Chem Soc 129:3148-56. 2007
    ..Finally, a nonconventional approach to photoinduced phenomena is proposed by differential spectroscopy in the FT-IR attenuated total reflectance (ATR) mode...
  88. ncbi Integrating single-wall carbon nanotubes into donor-acceptor nanohybrids
    Dirk M Guldi
    , Institute for Physical and Theoretical Chemistry, 91058 Erlangen, Germany
    Angew Chem Int Ed Engl 43:5526-30. 2004
  89. ncbi Carbon-nanotube shape and individualization critical for renal excretion
    Lara Lacerda
    Nanomedicine Laboratory, Centre for Drug Delivery Research The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N1AX, UK
    Small 4:1130-2. 2008
  90. ncbi Molecular design of strong single-wall carbon nanotube/polyelectrolyte multilayer composites
    Arif A Mamedov
    Chemistry Department, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Nat Mater 1:190-4. 2002
    ..Because of the lightweight nature of SWNT composites, the prepared free-standing membranes can serve as components for a variety of long-lifetime devices...
  91. ncbi Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses
    Davide Pantarotto
    , UPR 9021 CNRS, , , 67084 Strasbourg, France
    Chem Biol 10:961-6. 2003
  92. ncbi Hype around nanotubes creates unrealistic hopes
    Kostas Kostarelos
    Nature 453:280. 2008
  93. ncbi Opportunities and challenges of carbon-based nanomaterials for cancer therapy
    Alberto Bianco
    CNRS, Institut de Biologie Moleculaire et Cellulaire, UPR 9021 Immonulogie et Chimie Thérapeutiques, 67000 Strasbourg, France
    Expert Opin Drug Deliv 5:331-42. 2008
    ..A comparison between the characteristics, the advantages, the drawbacks, the benefits and the risks associated with these novel biocompatible forms of carbon is presented here...
  94. ncbi Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers
    Ravi Singh
    Centre for Drug Delivery Research, School of Pharmacy, University of London, UK
    Proc Natl Acad Sci U S A 103:3357-62. 2006
    ..This work describes the pharmacokinetic parameters of i.v. administered functionalized CNT relevant for various therapeutic and diagnostic applications...
  95. ncbi Chemistry of carbon nanotubes
    Dimitrios Tasis
    Department of Materials Science, University of Patras, 26504 Rio Patras, Greece
    Chem Rev 106:1105-36. 2006
  96. ncbi Langmuir-Shäfer transfer of fullerenes and porphyrins: formation, deposition, and application of versatile films
    Sabrina Conoci
    Sioptics and post Silicon Technologies, Corporate R and D STMicroelectronics, Stradale Primosole, 50, 95121 Catania, Italy
    Chemistry 10:6523-30. 2004
    ..Finally, photoaction spectra were recorded from films deposited by only one horizontal lifting onto indium-tin-oxide (ITO) electrodes and the observed photocurrent increased notably with increasing transfer surface pressure...
  97. ncbi Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors
    Ravi Singh
    Centre for Drug Delivery Research and Electron Microscopy Unit, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
    J Am Chem Soc 127:4388-96. 2005
    ..This study constitutes the first thorough investigation into the physicochemical interactions between cationic functionalized carbon nanotubes and DNA toward construction of carbon nanotube-based gene transfer vector systems...