Affiliation: University of Milan
- Kidney transplantation in patients with IgA mesangial glomerulonephritisC Ponticelli
Department of Nephro Urology and Kidney Transplantation, IRCCS Ospedale Maggiore, Via della Commenda 15, 20122 Milan, Italy
Kidney Int 60:1948-54. 2001....
- Decreased serum aminotransferase activity in patients with chronic renal failure: impact on the detection of viral hepatitisF Fabrizi
Division of Nephrology and Dialysis, Institute of Hygiene and Preventive Medicine, Maggiore Hospital, Milano, Italy
Am J Kidney Dis 38:1009-15. 2001..Studies aimed to clarify the pathogenesis of this phenomenon are in progress...
- Role of anaemia in cardiovascular mortality and morbidity in transplant patientsClaudio Ponticelli
Department of Nephro Urology and Kidney Transplantation, IRCCS Ospedale Maggiore di Milano, Via Commenda 15, 20122 Milan, Italy
Nephrol Dial Transplant 17:41-6. 2002..After transplantation, appropriate treatment of diabetes, hypertension and hyperlipidaemia, as well as avoidance of smoking, obesity and physical inactivity may reduce the risk of cardiovascular complications further...
- TT virus infection in end-stage renal disease (ESRD)F Fabrizi
Nephrology and Dialysis Division, University of California at Los Angeles, Los Angeles, California, USA
J Nephrol 14:80-7. 2001..The possibility that TTV causes pathological changes outside the liver cannot be ruled out. Further studies are in progress to understand the natural history and the epidemiology of TTV infection in patients with ESRD...
- Automated RIBA HCV strip immunoblot assay: a novel tool for the diagnosis of hepatitis C virus infection in hemodialysis patientsF Fabrizi
Division of Digestive Diseases, UCLA School of Medicine, Los Angeles, Calif, USA
Am J Nephrol 21:104-11. 2001..The CHIRON RIBA HCV 3.0 Processor System may be very useful for supplemental anti-HCV testing of ELISA repeat reactive specimens in clinical practice within dialysis units...
- Treatment of focal segmental glomerulosclerosisP Passerini
Division of Nephrology and Dialysis, IRCCS, Maggiore Hospital, Milan, Italy
Curr Opin Nephrol Hypertens 10:189-93. 2001..The role of other agents used in focal segmental glomerulosclerosis, including azathioprine, mycophenolate mofetil, tacrolimus, pefloxacin or vitamin E is still poorly defined...
- Epidemiology of hepatitis delta virus (HDV) infection in the dialysis populationF Fabrizi
Division of Nephrology and Dialysis, Maggiore Hospital, Policlinico IRCCS, Milano, Italy
Int J Artif Organs 25:8-17. 2002
- Long-term results of a randomized study comparing three immunosuppressive schedules with cyclosporine in cadaveric kidney transplantationG Montagnino
Divisione di Nefrologia e Dialisi, IRCCS, Ospedale Maggiore, Via Commenda 15, 20122 Milan, Italy
J Am Soc Nephrol 12:2163-9. 2001..The long-term renal function and survival were not affected in the patients on monotherapy who needed the addition of steroids. Monotherapy was associated with a lower incidence of extrarenal complications than the other two regimens...
- [Hepatopathy and hepatitis B virus infection in dialysis patients: cross-sectional study]F Fabrizi
Divisioni di Nefrologia e Dialisi, Ospedale Maggiore, IRCCS, Milano, Italy
G Ital Nefrol 19:149-54. 2002..The clinical significance related to the presence of HBsAg in serum of dialysis patients has not been completely understood...
- Hepatitis C virus infection and rituximab therapy after renal transplantationF Fabrizi
Division of Nephrology and Dialysis, Maggiore Hospital, IRCCS, Milan, Italy
Int J Artif Organs 30:445-9. 2007..Rituximab, a chimeric monoclonal antibody, has been successfully given in various diseases including HCV-associated mixed cryoglobulinemia. However, only preliminary data exists on its efficacy and safety after renal transplantation...
- Natural history of hepatitis C virus infection in adult renal graft recipientsA Aroldi
Divisione de Nefrologia e Dialisi, Istituto di Medicina Interna, Istituto di Igiene e Medicina Preventiva, Ospedale Maggiore Milano IRCCS, Milan, Italy
Transplant Proc 37:940-1. 2005..To study the natural history of hepatitis C virus infection in renal transplantation, 464 HbsAg negative patients were prospectively studied from 1989...
- The clinical status of cadaveric renal transplant patients treated for 10 year with cyclosporine therapyC Ponticelli
Divisione di Nefrologia e Dialisi, IRCCS, Ospedale Maggiore, Milan, Italy
Clin Transplant 13:324-9. 1999..2 and 201 +/- 143.0 mg/dL, respectively). Most patients have a high degree of rehabilitation 10 yr after uninterrupted cyclosporine therapy and all patients but 3 were able to work...
- Influence of hepatitis B virus virema upon serum aminotransferase activity in dialysis populationF Fabrizi
Division of Nephrology, Dialysis and Transplantation, Maggiore Hospital, IRCCS, Milano, Italy
Int J Artif Organs 26:1048-55. 2003..Also, the clinical impact related to the virological characteristics of HBV in dialysis has not been evaluated...
- A randomized, double-blind trial of basiliximab immunoprophylaxis plus triple therapy in kidney transplant recipientsC Ponticelli
Divisione Nefrologia e Dialisi, IRCCS Ospedale Maggiore Policlinico, Via Commenda 15, 20122, Milano, Italy
Transplantation 72:1261-7. 2001....
- Can prolonged treatment improve the prognosis in adults with focal segmental glomerulosclerosis?C Ponticelli
Divisione di Nefrologia e Dialisi, IRCCS Ospedale Maggiore di Milano, Milano, Italy
Am J Kidney Dis 34:618-25. 1999..This study shows that 70% of nephrotic adults with FSGS may obtain complete or partial remission and maintain stable renal function for about 10 years when given a prolonged therapy with corticosteroids or immunosuppressive drugs...
- Calcineurin inhibitors in renal transplantation still needed but in reduced doses: a reviewC Ponticelli
Division of Nephrology, Scientific Institute Humanitas, Milano, Italy
Transplant Proc 42:2205-8. 2010..Such an approach seems therefore preferable to complete elimination of CNIs with substitution of the current immunosuppressive drugs...
- From cyclosporine to the futureC Ponticelli
Division of Nephrology, Ospedale Maggiore IRCCS, Milano, Italy
Transplant Proc 36:557S-560S. 2004....
- A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and cyclosporineG Montagnino
Department of Renal Transplant, University of Milano, Milan, Italy
Transplant Proc 37:788-90. 2005..About 60% of patients given everolimus and low-dose CsA can definitively stop steroids after 1 week...
- [Natural history of HBV in dialysis population]F Fabrizi
Divisione di Nefrologia e Dialisi, Istituto di Igiene e Medicina Preventiva, Ospedale Maggiore, IRCCS, Milano, Italy
G Ital Nefrol 21:21-8. 2004..Prospective clinical trials are under way to better define the virological features of HBV in the dialysis population...
- Hepatitis C virus infection and renal transplantationF Fabrizi
Division of Nephrology and Dialysis, Maggiore Hospital, IRCCS, Milano, Italy
Am J Kidney Dis 38:919-34. 2001....
- Double recurrence of FSGS after two renal transplants with complete regression after plasmapheresis and ACE inhibitorsG Montagnino
Divisione di Nefrologia e Dialisi, Ospedale Maggiore IRCCS, Milan, Italy
Transpl Int 13:166-8. 2000....
- Necrotizing glomerulonephritis in a living donor kidney transplant recipientM Campise
Divisione di Nefrologia, IRCCS Ospedale Maggiore, Milano, Italy
Transplant Proc 35:1368-9. 2003..7 mg/dL and mild proteinuria. To the best of our knowledge this is the first case of recovery from a necrotizing glomerulonephritis in a renal transplant recipient...
- Renal transplantation in lupus nephritisC Ponticelli
IRCCS Instituto Auxologicio, Milan, Italy
Lupus 14:95-8. 2005..When some selection criteria are respected, the results of renal trasplantation in SLE patients are at least as good as in other transplant recipients...
- [Natural history of hepatitis B virus infection in dialysis patients: prospective study by quantitative analysis of HBV viremia]F Fabrizi
Divisione di Nefrologia e Dialisi, Ospedale Maggiore, IRCCS, Milano
G Ital Nefrol 19:294-300. 2002..Amplicor HBV MonitorTM Test Kit amplifies a sequence in the pre-Core/Core region of the HBV genome with biotinylated and non-biotinylated oligonucleotide primers...
- Renal transplantation strengths and shortcomingsC Ponticelli
Nephrology and Dialysis Division, IRCCS Ospedale Maggiore, Milan, Italy
J Nephrol 14:S1-6. 2001..Use of marginal donors, non-heart-beating donors, and living unrelated donors has been recommended by many authorities to overcome the shortage of organs...
- Steroid-sparing strategiesC Ponticelli
IRCCS Istituto Scientifico Auxologico, Milano, Italy
Transplant Proc 37:3597-9. 2005..The available data indicate that an early elimination of corticosteroids is feasible today in many renal transplant recipients. A steroid-sparing strategy may reduce the side effects and improve the compliance of transplant recipients...
- The different patterns of response to plasmapheresis of recurrent focal and segmental glomerulosclerosisC Ponticelli
U O Nefrologia IRCCS Ospedale Maggiore, Milano, Italy
Transplant Proc 34:3069-71. 2002
- Continuous ambulatory peritoneal dialysis in patients after intra-abdominal prosthetic vascular graft surgeryM Maccario
Division of Nephrology and Dialysis, IRCCS Ospedale Maggiore, Milano, Italy
Nephron 77:159-63. 1997..A similar peritonitis and cardiovascular complication rate was observed in a control group of age- and sex-matched CAPD patients with no aortic prosthesis. We conclude that CAPD is feasible in patients with abdominal aortic prosthesis...
- Design of a trial comparing sirolimus plus mycophenolate mofetil versus sirolimus plus cyclosporineC Ponticelli
Renal Unit Ospedale Maggiore, Milano, Italy
Transplant Proc 35:62S-63S. 2003..The primary endpoint will be the graft function at 3, 6, 12, 24, 36, 48, and 60 months. A number of secondary endpoints will also be considered. To obtain a significant difference in the primary endpoint 180 patients will be enrolled...
- Preliminary evaluation of incremental peritoneal dialysis in 25 patientsA F De Vecchi
Peritoneal Dialysis Program, Division of Nephrology and Dialysis, IRCCS Ospedale Maggiore Policlinico di Milano, Italy
Perit Dial Int 20:412-7. 2000..Incremental dialysis has been suggested for patients with some residual renal function. However, very little published clinical data exist on the feasibility of this schedule...
- Cyclosporine in idiopathic nephrotic syndromeC Ponticelli
Divisione Nefrologia e Dialisi, IRCCS Ospedale Maggiore, Milano, Italy
Immunopharmacol Immunotoxicol 15:479-89. 1993..On the basis of renal histology two main types of INS are recognized: minimal change nephropathy (MCN) and focal and segmental glomerular sclerosis (FSGS)...
- De novo thrombotic microangiopathy. An underrated complication of renal transplantationC Ponticelli
Instituto Auxologico Italiano, Milano, Italy
Clin Nephrol 67:335-40. 2007..Early plasmapheresis could improve clinical signs and symptoms and rescue renal function in a number of patients. Anecdotal successes have also been reported with intravenous immunoglobulins and rituximab...
- Promising new agents in the prevention of transplant rejectionC Ponticelli
Divisione di Nefrologia e Dialisi, IRCCS Ospedale Maggiore di Milano, Italy
Drugs R D 1:55-60. 1999....
- The case against protocol kidney biopsiesC Ponticelli
Division of Nephrology, IRCCS Ospedale Maggiore di Milano, Via Commenda 15, 20122 Milan, Italy
Transplant Proc 34:1716-8. 2002
- Risk factors associated to kidney stones in primary hyperparathyroidismS Corbetta
Institute of Endocrine Sciences, Fondazione Ospedale Maggiore IRCCS, University of Milan, Milan, Italy
J Endocrinol Invest 28:122-8. 2005..In conclusion, hypercalciuria, higher oxalate excretion and severe PHPT are associated with kidney stones in PHPT...
- Gitelman syndrome: pathophysiological and clinical aspectsG Graziani
Nephrology and Dialysis Unit, IRCCS Istituto Clinico Humanitas, Rozzano, Milano, Italy
QJM 103:741-8. 2010..Moreover, the differential diagnosis between other similar electrolyte-induced clinical disorders and GS is also discussed...
- Immediate graft function positively affects long-term outcome of renal allografts from older but not from younger donorsP Messa
Nephrology and Dialysis Unit, Ospedale Maggiore Policlinico Milan ITA, Milan, Italy
Transplant Proc 38:3377-81. 2006..In older donor recipients, DGF was an independent variable associated with a poor graft outcome. In younger donor recipients, duration of dialysis and rejection were the most important predictors of poor graft outcomes...
- Renal replacement therapy in lupus nephritisGabriella Moroni
Division of Nephrology, IRCCS Maggiore Hospital, Milan, Italy
J Nephrol 16:787-91. 2003..The recurrence risk of lupus nephritis ranged between 2% and 30% in different studies. The histological picture does not usually show severe features. Antiplatelet agents or anticoagulation can be advised for aPL patients...
- The long-term prognosis of renal transplantation in patients with lupus nephritisGabriella Moroni
Divisione di Nefrologia e Dialisi, Centro Trasfusionale e di Immunologia dei Trapianti IRCCS, Ospedale Maggiore Milano, Italy
Am J Kidney Dis 45:903-11. 2005..Few data are available about the long-term outcome of renal transplantation in patients with systemic lupus erythematosus (SLE)...
- The clinical impact of chronic transplant glomerulopathy in cyclosporine eraGiovanni Banfi
Division of Nephrology Ospedale Maggiore IRCCS, Milan, Italy croff1policlinico mi it
Transplantation 80:1392-7. 2005..A retrospective study of renal transplant recipients at Ospedale Maggiore of Milan was undertaken to evaluate the clinical outcome of patients with CTG...
- Risk factors for cardiovascular events after successful renal transplantationYves F C Vanrenterghem
Department of Nephrology, University Hospital of K U Leuven, Leuven, Belgium
Transplantation 85:209-16. 2008....
- Antiphospholipid antibodies are associated with an increased risk for chronic renal insufficiency in patients with lupus nephritisGabriella Moroni
Division of Nephrology and Dialysis, IRCCS Ospedale Maggiore, Milan, Italy
Am J Kidney Dis 43:28-36. 2004..The aims of this study are to evaluate the prevalence of aPL antibodies in patients with lupus nephritis and assess their prognostic value for thrombosis and pregnancy morbidity and impact on long-term renal outcome...
- Acute post-bacterial glomerulonephritis in renal transplant patients: description of three cases and review of the literatureGabriella Moroni
Division of Nephrology and Dialysis Ospedale Maggiore Policlinico IRCCS, Milan, Italy
Am J Transplant 4:132-6. 2004..It has an unusual presentation and may have a poor outcome in the long term. The role of therapy, if any, is still undefined...
- Pregnancy in lupus nephritisGabriella Moroni
Divisione di Nefrologia e Dialisi, IRCCS Ospedale Maggiore Policlinico, Milano and the Dipartimento di Informatica e Sistemistica, Universita degli Studi di Pavia, Italy
Am J Kidney Dis 40:713-20. 2002..Fetal and maternal outcomes of 70 pregnancies in 48 women with lupus nephritis were retrospectively analyzed...
- Long-term prognosis of diffuse proliferative glomerulonephritis associated with infection in adultsGabriella Moroni
Divisione di Nefrologia e Dialisi, IRCCS Ospedale Maggiore Policlinico, Milano, Italy
Nephrol Dial Transplant 17:1204-11. 2002..Infection-associated glomerulonephritis is rare in adults and its long-term prognosis is undefined...
- [Acute post-infective glomerulonephritis]Gabriella Moroni
Recenti Prog Med 94:395-8. 2003....
- Risk factors for late kidney allograft failureClaudio Ponticelli
Divisione di Nefrologia e Dialisi, and Epidemiologic Unit, IRCCS Ospedale Maggiore Milano, Milano, Italy
Kidney Int 62:1848-54. 2002..We evaluated the causes of late failure in renal allograft recipients treated with cyclosporine A (CsA)...
- The risk of pregnancy in patients with lupus nephritisGabriella Moroni
Division of Nephrology and Dialysis, Maggiore Hospital, IRCCS Policlinico, Via della Commenda 15, 20122 Milan, Italy
J Nephrol 16:161-7. 2003..Nevertheless the fetal risk, although progressively reduced during the last 40 years, continues to be higher than in pregnancies of healthy women particularly in patients with antiphospholipid antibodies...
- Other immunosuppressive agents for focal segmental glomerulosclerosisClaudio Ponticelli
Division of Nephrology, IRCCS, Ospedale Maggiore, Milano, Italy
Semin Nephrol 23:242-8. 2003..The preliminary results with plasmapheresis or lipopheresis are promising but further studies are needed to assess the role of these treatments...
- Gastrointestinal complications in renal transplant recipientsClaudio Ponticelli
Clinical Immunology Unit, IRCCS Istituto Auxologico Italiano, Milano, Italy
Transpl Int 18:643-50. 2005..A particular gastric lymphoma called mucosa-associated lymphoid tissue (MALT) lymphoma may develop in renal transplant patients. It usually responds to the eradication of Helicobacter pylori...
- Thrombotic microangiopathy after kidney transplantationClaudio Ponticelli
Department of Immunology, IRCCS, Istituto Auxologico Italiano, Milan, Italy
Transpl Int 19:789-94. 2006..The prognosis is less severe than with recurrent TMA. Complete withdrawal of the offending drug may lead to improvement in many cases. The addition of plasma exchange may result in graft salvage in about 80% of cases...
- Withdrawal of therapy in patients with proliferative lupus nephritis: long-term follow-upGabriella Moroni
Division of Nephrology, Ospedale Maggiore IRCCS, Via Commenda 15, 20122 Milan, Italy
Nephrol Dial Transplant 21:1541-8. 2006..Whether corticosteroid and immunosuppressive therapy may be safely withdrawn in patients with proliferative lupus nephritis is still unclear...
- A randomized pilot trial comparing methylprednisolone plus a cytotoxic agent versus synthetic adrenocorticotropic hormone in idiopathic membranous nephropathyClaudio Ponticelli
Istituto Scientifico Auxologico Italiano, Milan, Italy
Am J Kidney Dis 47:233-40. 2006..We conducted a pilot trial to compare the effectiveness and safety of 2 different treatments in patients with membranous nephropathy and nephrotic syndrome...
- Calcium and phosphate plasma levels in dialysis patients after dietary Ca-P overload. Role of gastric acid secretionGiorgio Graziani
Division of Internal Medicine, Nephrology and Dialysis, Istituto Clinico Humanitas, Via Manzoni 56, I 20089 Rozzano, Milan, Italy
Nephron 91:474-9. 2002..In contrast, with the "trade off" hypothesis we did not observe any postprandial phosphate peak after the dietary load, and, in contrast with normal subjects, omeprazole administration did not influence the phosphate profile...
- Epidemiology of GB virus c/hepatitis g virus infection in patients on peritoneal dialysisFabrizio Fabrizi
Perit Dial Int 22:405-10. 2002..The epidemiology of GBV-C/HGV infection in patients on peritoneal dialysis is scarce and mostly based on RT-PCR technology...
- Neurological complications in kidney transplant recipientsClaudio Ponticelli
IRCCS, Italian Auxologic Institute, Milan Italy
J Nephrol 18:521-8. 2005....
- BK polyomavirus interstitial nephritis in a renal transplant patient with no previous acute rejection episodesAttilio Elli
Nephrology and Dialysis Division, Maggiore Hospital IRCCS, Milan, Italy
J Nephrol 15:313-6. 2002..This case shows that even in the absence of vigorous anti-rejection therapy an immunosuppressive regimen based on tacrolimus and MMF may involve the risk of BK polyoma virus- associated interstitial nephritis...
- Abnormalities of homocysteine and B vitamins in the nephrotic syndromeGian Marco Podda
Centro Emofilia e Trombosi Angelo Bianchi Bonomi, Dipartmento di Medicina Interna e Dermatologia, Fondazione I R C C S Ospedale Maggiore, Mangiagalli e Regina Elena, Universita di Milano, Italy
Thromb Res 120:647-52. 2007..The prevalence in the nephrotic syndrome of high circulating levels of homocysteine and of low levels of the B vitamins that are involved in its metabolism, which may play a role in thrombosis, is not well defined...
- The long-term outcome of 93 patients with proliferative lupus nephritisGabriella Moroni
Unita Operativa di Nefrologia e Dialisi, Fondazione Ospedale Maggiore Policlinco, Mangiagalli, Regina Elena IRCCS, Via F Sforza, Milano, and Dipartimento di Informatica e Sistemistica, Universita degli Studi di Pavia, Italy
Nephrol Dial Transplant 22:2531-9. 2007..Few data are available about the very long-term outcome of patients with proliferative lupus nephritis...
- Evidence against hepatitis C virus trapping in dialysis membranesClaudio Angelini
Nephrol Dial Transplant 17:317-8. 2002
- Hepatitis B virus and renal transplantationFabrizio Fabrizi
Nephron 90:241-51. 2002
- Serological and genetic factors in early recurrence of IgA nephropathy after renal transplantationRosanna Coppo
Nephrology, Dialysis and Transplantation Unit, Regina Margherita Turin, Italy
Clin Transplant 21:728-37. 2007..The relative role of IgA anomalies and genetic factors in IgA nephropathy (IgAN) recurrence after transplantation has never been investigated in a single cohort...
- New recommendations in the treatment of Gram-positive bacteraemia in dialysis patientsClaudio Ponticelli
Nephrol Dial Transplant 23:27-32. 2008
- A randomized exploratory trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporineGiuseppe Montagnino
Nephrology Unit, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, IRCCS, Milan, 20122, Italy
Nephrol Dial Transplant 23:707-14. 2008..In this randomized trial, we explored whether the use of everolimus associated with low-dose cyclosporine could allow an early avoidance of steroids in de novo renal transplant recipients...
- A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four yearsGabriella Moroni
Division of Nephrology, IRCCS Ospedale Maggiore, Via Commenda 15, 20122 Milano, Italy
Clin J Am Soc Nephrol 1:925-32. 2006..For patients with diffuse proliferative lupus nephritis, azathioprine or cyclosporine combined with corticosteroids demonstrated equal efficacy in the prevention of flares...
- New therapies for lupus nephritisClaudio Ponticelli
Istituto Auxologico Italiano, Via Ampere 126, 20131 Milano, Italy
Clin J Am Soc Nephrol 1:863-8. 2006
- Can mTOR inhibitors reduce the risk of late kidney allograft failure?Claudio Ponticelli
Department of Immunology, Istituto Auxologico Italiano, Milano, Italy
Transpl Int 21:2-10. 2008..All of these characteristics offer a ray of hope for reducing the risk of long-term allograft failure...
- Outcome of peritoneal dialysis in cirrhotic patients with chronic renal failureAmedeo F De Vecchi
Divisione di Nefrologia e Dialisi and Dipartimento di Medicina Interna, IRCCS Ospedale Maggiore Policlinico, Milano, Italy
Am J Kidney Dis 40:161-8. 2002..Results of peritoneal dialysis (PD) in cirrhotic patients with renal failure are debated. The aim of the present study is to assess the outcome of PD patients with liver cirrhosis...
- Long-term lamivudine monotherapy in renal-transplant recipients with hepatitis-B-related cirrhosisMauro Vigano
Department of Gastroenterology and Endocrinology, IRCCS Maggiore Hospital and University of Milan, Milan, Italy
Antivir Ther 10:709-13. 2005..The aim of the study was to assess the efficacy and safety of long-term lamivudine monotherapy in renal-transplant recipients with HBV-related cirrhosis...
- Cyclosporine: from renal transplantation to autoimmune diseasesClaudio Ponticelli
IRCCS Istituto Auxologico Italiano, FRCP, Via Ampere 126, 20131 Milan, Italy
Ann N Y Acad Sci 1051:551-8. 2005..If these guidelines are followed, CsA may be safely used in autoimmune diseases...
- Prevalence and management of anemia in renal transplant recipients: a European surveyYves Vanrenterghem
Department of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium
Am J Transplant 3:835-45. 2003..Further studies should be carried out to interpret whether appropriate management of anemia after kidney transplantation may improve long-term outcome...
- Impact of chronic allograft nephropathy and subsequent modifications of immunosuppressive therapy on late graft outcomes in renal transplantationGiuseppe Montagnino
Divisione di Nefrologia e Dialisi, Ospedale Maggiore di Milano, IRCCS, Via Commenda 15, 20122 Milan, Italy
Nephrol Dial Transplant 19:2622-9. 2004..Chronic allograft nephropathy (CAN) is the leading cause of organ failure in renal transplant recipients. We retrospectively evaluated the impact of varying immunosuppression in CAN patients on long-term graft survival...
- Renal transplantation in patients with IgA mesangial glomerulonephritisClaudio Ponticelli
Department of Nephro urology, IRCCS Ospedale Maggiore di Milano, Via Commenda 15, 20122 Milan, Italy
Pediatr Transplant 8:334-8. 2004..Little information is available on the impact of recurrence in the very long term. There is no established treatment for preventing or treating the recurrence of IgA nephritis...
- Changes in viremia and circulating interferon-alpha during hemodialysis in hepatitis C virus-positive patients: only coincidental phenomena?Salvatore Badalamenti
Division of Nephrology, Istituto Clinico Humanitas, Milan, Italy
Am J Kidney Dis 42:143-50. 2003..The aim of the present study in HCV-positive (HCV+) HD patients is to determine whether HD induces the production of interferon-alpha (IFN-alpha) and if such production can contribute to viremia reduction...
- Chronic allograft nephropathyClaudio Ponticelli
N Engl J Med 350:1254-6; author reply 1254-6. 2004
- Altruistic living renal transplantationClaudio Ponticelli
Division of Nephrology, IRCCS Maggiore Hospital, Milan, Italy
J Nephrol 16:S6-9. 2003..At present, there is no evidence that mononephrectomy in healthy subjects can expose them to an increased risk of renal failure, even in the long-term...
- Oxidative stress in kidney transplant patientsMariarosaria Campise
U O Nefrologia, IRCCS Ospedale Maggiore, Milan, Italy
Transplantation 76:1474-8. 2003..Little information is available about the role of oxidative stress in renal transplant patients. To evaluate the prevalence and severity of oxidative stress in renal transplantation, the authors conducted a cross-sectional study...
- Successful treatment of hemolytic uremic syndrome after liver-kidney transplantationStefano Gatti
Liver Transplant Unit, IRCCS Maggiore Hospital, Milan, Italy
J Nephrol 16:586-90. 2003..The syndrome is a well-recognized complication in bone marrow transplantation, and has been likewise described in several cases of solid organs transplantation, but never in patients receiving combined liver and kidney transplantation...
- Is cyclosporine in renal-transplant recipients more effective when given twice a day than in a single daily dose?Antonio Tarantino
Ospedale Maggiore IRCCS, U O Nefrologia e Dialisi, via della Comenda 15, 20122 Milan, Italy
Transplantation 78:675-80. 2004..It is still unknown whether it is better to administer cyclosporine (CsA) once or twice a day to renal-transplant patients...
- Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label studyBjorn Nashan
Kliniken der med Hochschule, Zentrum Chirurgie, Hannover, Germany
Transplantation 78:1332-40. 2004..Everolimus and cyclosporine (CsA) exhibit synergistic immunosuppressive activity when used in combination. We explored the use of everolimus with a CsA-sparing strategy in de novo renal-transplant recipients...
- Renal transplantation 2004: where do we stand today?Claudio Ponticelli
Ospedale San Luca, vie spagnotetto 13, 1 20149, Italy
Nephrol Dial Transplant 19:2937-47. 2004....
- Transplant glomerulopathy: new clues in the puzzle of chronic allograft nephropathy?Claudio Ponticelli
Am J Transplant 3:1043-4. 2003
- Natural history of hepatitis B and C in renal allograft recipientsAdriana Aroldi
Divisione di Nefrologia e Dialisi, Unita Operativa Nefrologia e Dialisi, Ospedale Maggiore IRCCS, Milano, Italy
Transplantation 79:1132-6. 2005..The natural history of hepatitis C and B was studied in 286 renal allograft recipients who received a kidney allograft between 1972 and 1989 when tests for anti-HCV became available...
- Clinical experience with everolimus (Certican): a summaryClaudio Ponticelli
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Transplantation 79:S93-4. 2005
- Guest editor's introductionClaudio Ponticelli
Transplantation 79:S69-71. 2005
- Depletion of clusterin in renal diseases causing nephrotic syndromeGian Marco Ghiggeri
Laboratory on Pathophysiology of Uremia and Unit of Nephrology, Istituto Giannina Gaslini, Genova, Italy
Kidney Int 62:2184-94. 2002..In focal segmental glomerulosclerosis (FSGS), it inhibits permeability plasma factor activity and could influence proteinuria. Moreover, with aging, knockout mice for clusterin develop a progressive glomerulopathy with sclerosis...
- Therapeutic drug monitoring for everolimus in kidney transplantation using 12-month exposure, efficacy, and safety dataMarc I Lorber
Yale University School of Medicine, New Haven, CT, USA
Clin Transplant 19:145-52. 2005..This investigation indicates that improved efficacy is likely when TDM is considered as an integral component of the immunosuppressive strategy of everolimus...
- Biological dynamics of hepatitis B virus load in dialysis populationFabrizio Fabrizi
Nephrology and Dialysis Division, Institute of Hygiene and Preventive Medicine, Maggiore Hospital, IRCCS, Milano, Italy
Am J Kidney Dis 41:1278-85. 2003..The aim of this study is to measure monthly HBV viral load (HBV DNA) in a large cohort (n = 29) of hepatitis B surface antigen (HBsAg)-positive chronic dialysis patients during 12 months...
- Generic cyclosporine: a word of cautionClaudio Ponticelli
IRCCS Istituto Auxologico, Milano, Italy
J Nephrol 17:S20-4. 2004..A main problem is the absence of long-term studies with generic CsA, in the complex setting of organ transplantation...
- Corticosteroid effectiveness in IgA nephropathy: long-term results of a randomized, controlled trialClaudio Pozzi
Department of Nephrology and Dialysis, A Manzoni Hospital, Lecco, Italy
J Am Soc Nephrol 15:157-63. 2004..The histologic picture and proteinuria during early and late follow-up improve the prediction of outcome, but considerable variability remains outside the model...