N Pluchino

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. pmc Brain derived neurotrophic factor circulating levels in patients undergoing IVF
    P Monteleone
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    J Assist Reprod Genet 24:477-80. 2007
  2. doi request reprint Androgen therapy in women: for whom and when
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100, Pisa, Italy
    Arch Gynecol Obstet 288:731-7. 2013
  3. doi request reprint Effect of DHEA therapy on sexual behavior in female rats
    Nicola Pluchino
    Department of Reproductive Medicine, Division of Gynaecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 29:496-502. 2013
  4. ncbi request reprint Efficacy of a topical cosmetic slimming treatment for postmenopausal women: a randomized, double-blind, placebo controlled trial
    N Pluchino
    Division of Gynecology and Obstetrics, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy
    Minerva Ginecol 65:79-88. 2013
  5. doi request reprint Office vaginoscopic hysteroscopy in infertile women: effects of gynecologist experience, instrument size, and distention medium on patient discomfort
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    J Minim Invasive Gynecol 17:344-50. 2010
  6. doi request reprint Brain-region responsiveness to DT56a (Femarelle) administration on allopregnanolone and opioid content in ovariectomized rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Menopause 16:1037-43. 2009
  7. doi request reprint Sex differences in brain and plasma beta-endorphin content following testosterone, dihydrotestosterone and estradiol administration to gonadectomized rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Neuroendocrinology 89:411-23. 2009
  8. doi request reprint Spontaneous cornual pregnancy after homolateral salpingectomy for an earlier tubal pregnancy: a case report and literature review
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, University of Pisa, Italy
    J Minim Invasive Gynecol 16:208-11. 2009
  9. doi request reprint Sexually dimorphic effects of testosterone administration on brain allopregnanolone in gonadectomized rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    J Sex Med 5:2780-92. 2008
  10. doi request reprint Daily variation of brain-derived neurotrophic factor and cortisol in women with normal menstrual cycles, undergoing oral contraception and in postmenopause
    N Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    Hum Reprod 24:2303-9. 2009

Collaborators

Detail Information

Publications43

  1. pmc Brain derived neurotrophic factor circulating levels in patients undergoing IVF
    P Monteleone
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    J Assist Reprod Genet 24:477-80. 2007
    ....
  2. doi request reprint Androgen therapy in women: for whom and when
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100, Pisa, Italy
    Arch Gynecol Obstet 288:731-7. 2013
    ....
  3. doi request reprint Effect of DHEA therapy on sexual behavior in female rats
    Nicola Pluchino
    Department of Reproductive Medicine, Division of Gynaecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 29:496-502. 2013
    ..Hormonal treatment using physiological doses of delta-5 androgens (DHEA) positively affects sexual motivation in OVX rats...
  4. ncbi request reprint Efficacy of a topical cosmetic slimming treatment for postmenopausal women: a randomized, double-blind, placebo controlled trial
    N Pluchino
    Division of Gynecology and Obstetrics, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy
    Minerva Ginecol 65:79-88. 2013
    ....
  5. doi request reprint Office vaginoscopic hysteroscopy in infertile women: effects of gynecologist experience, instrument size, and distention medium on patient discomfort
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    J Minim Invasive Gynecol 17:344-50. 2010
    ..To assess the roles of instrument diameter (5.0- or 3.5-mm external sheath), uterine distention medium (carbon dioxide [CO(2)] or saline solution), and hysteroscopist experience in diagnostic hysteroscopy...
  6. doi request reprint Brain-region responsiveness to DT56a (Femarelle) administration on allopregnanolone and opioid content in ovariectomized rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Menopause 16:1037-43. 2009
    ....
  7. doi request reprint Sex differences in brain and plasma beta-endorphin content following testosterone, dihydrotestosterone and estradiol administration to gonadectomized rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Neuroendocrinology 89:411-23. 2009
    ....
  8. doi request reprint Spontaneous cornual pregnancy after homolateral salpingectomy for an earlier tubal pregnancy: a case report and literature review
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, University of Pisa, Italy
    J Minim Invasive Gynecol 16:208-11. 2009
    ....
  9. doi request reprint Sexually dimorphic effects of testosterone administration on brain allopregnanolone in gonadectomized rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    J Sex Med 5:2780-92. 2008
    ..Clinical and biological evidences have shown a wide range of neuroactive effects of testosterone administration...
  10. doi request reprint Daily variation of brain-derived neurotrophic factor and cortisol in women with normal menstrual cycles, undergoing oral contraception and in postmenopause
    N Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    Hum Reprod 24:2303-9. 2009
    ..We aimed to investigate whether BDNF circadian rhythms exist in women and if there is a relationship with cortisol circadian rhythmicity. Moreover, we aimed to establish whether the hormonal status influences BDNF diurnal variations...
  11. doi request reprint Menopause and mental well-being: timing of symptoms and timing of hormone treatment
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Womens Health (Lond) 7:71-80. 2011
    ....
  12. ncbi request reprint Tibolone, transdermal estradiol or oral estrogen-progestin therapies: effects on circulating allopregnanolone, cortisol and dehydroepiandrosterone levels
    N Pluchino
    Division of Obstetrics and Gynecology, University of Pisa, Italy
    Gynecol Endocrinol 20:144-9. 2005
    ..Unlike estrogen-based therapy, tibolone treatment did not reduce the DHEA milieu in the menopause, and thus did not enhance the androgen deficiency syndrome in postmenopausal women...
  13. ncbi request reprint Influence of endogenous and exogenous sex hormones on plasma brain-derived neurotrophic factor
    S Begliuomini
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Hum Reprod 22:995-1002. 2007
    ..Brain-derived neurotrophic factor (BDNF) is a mediator of neuronal plasticity and influences learning, memory and cognitive behaviour. The aim of this study is to assess plasma BDNF variations according to hormonal status...
  14. doi request reprint Central modifications of allopregnanolone and beta-endorphin following subcutaneous administration of Nestorone
    E Lenzi
    Department of Reproductive Medicine and Child Development, Division of Gynaecology and Obstetrics, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    J Steroid Biochem Mol Biol 116:15-20. 2009
    ..This suggests that Nestorone at the antiovulatory dose levels may not alter the positive effects of estrogen treatment on mood and behaviour...
  15. doi request reprint Advances in neurosteroids: role in clinical practice
    N Pluchino
    Division of Obstetrics and Gynecology, University of Pisa, Italy
    Climacteric 16:8-17. 2013
    ..The brain metabolism of synthetic progestins and the implications of DHEA treatment in postmenopausal women will also be discussed...
  16. doi request reprint Effect of 1-year, low-dose DHEA therapy on climacteric symptoms and female sexuality
    A R Genazzani
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa
    Climacteric 14:661-8. 2011
    ..Sexual desire is affected by endocrine and psychosocial factors. Menopausal hormonal changes are relevant to the causes of sexual dysfunction during reproductive aging...
  17. doi request reprint Evaluation of brain-derived neurotrophic factor in menstrual blood and its identification in human endometrium
    N Russo
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 28:492-5. 2012
    ..The detection of BDNF in the human menstrual blood and endometrium further supports the role of this neurotrophin in female reproductive function...
  18. doi request reprint Progestogens and brain: an update
    N Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynaecology and Obstetrics, University of Pisa, Via Roma 35, Pisa, Italy
    Maturitas 62:349-55. 2009
    ..The aim of the present paper is to briefly review and compare neuroendocrine effects of progestogens with special reference to P metabolism into neuroactive steroids and the opioids system...
  19. ncbi request reprint Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and beta-endorphin
    Francesca Bernardi
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    Fertil Steril 83:1161-8. 2005
    ....
  20. ncbi request reprint Disadaptive disorders in women: allopregnanolone, a sensitive steroid
    F Bernardi
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 19:344-53. 2004
    ....
  21. ncbi request reprint Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels
    Francesca Bernardi
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Neuroendocrinology 83:348-59. 2006
    ..Their association with an estrogenic compound does not interfere with the positive effects produced by estrogen on allopregnanolone and beta-END brain content...
  22. doi request reprint Robotic single-site hysterectomy: feasibility, learning curve and surgical outcome
    V Cela
    Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Surg Endosc 27:2638-43. 2013
    ..The robotic single-site surgery is the inevitable hybridization of robotic technology with laparoendoscopic single-site surgery...
  23. ncbi request reprint Progesterone and progestins: effects on brain, allopregnanolone and beta-endorphin
    N Pluchino
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynaecology, University of Pisa, Pisa, Italy
    J Steroid Biochem Mol Biol 102:205-13. 2006
    ..This may have far-reaching implications for the clinical effects and related indications of each compound...
  24. doi request reprint One-year therapy with 10mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Maturitas 59:293-303. 2008
    ..However, the aging process and the number of years since menopause may further modulate the effects of hormone therapy on hormonal milieu...
  25. doi request reprint Polycystic ovary syndrome: brain-derived neurotrophic factor (BDNF) plasma and follicular fluid levels
    N Russo
    Department of Reproductive Medicine and Child Development, Division of Gynaecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 28:241-4. 2012
    ..Therefore we can hypothsize that high levels of luteinizing hormone, probably increase the secretion of BDNF in PCOS patients...
  26. ncbi request reprint Effect of different hormonal replacement therapies on circulating allopregnanolone and dehydroepiandrosterone levels in postmenopausal women
    F Bernardi
    Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 17:65-77. 2003
    ..In conclusion, HRT strongly modifies circulating neurosteroid levels in postmenopausal women...
  27. doi request reprint Fertility and endocrine outcome after robot-assisted laparoscopic myomectomy (RALM)
    V Cela
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 29:79-82. 2013
    ....
  28. ncbi request reprint CNS: sex steroids and SERMs
    F Bernardi
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology P Fioretti, University of Pisa, Via Roma 35, 56100 Pisa, Italy
    Ann N Y Acad Sci 997:378-88. 2003
    ..The effects of raloxifene on mood and cognition encourage the efforts in the research of an ideal estrogen replacement therapy, showing all the positive effects of estrogens and fewer side effects...
  29. doi request reprint Effects of nomegestrol acetate administration on central and peripheral beta-endorphin and allopregnanolone in ovx rats
    Elena Lenzi
    Department of Reproductive Medicine and Child Development, Division of Gynaecology and Obstetrics, University of Pisa, Pisa, Italy
    J Steroid Biochem Mol Biol 110:67-75. 2008
    ....
  30. ncbi request reprint Androgen replacement therapy and cardiovascular function
    A R Genazzani
    Department of Reproductive Medicine and Child Development, Section of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Climacteric 12:102-7. 2009
    ..The present short review examines the effect of androgen on the cardiovascular system, with particular regard to dehydroepiandrosterone and testosterone replacement in postmenopausal women...
  31. doi request reprint Steroid hormones and BDNF
    N Pluchino
    Division of Obstetrics and Gynecology, University of Pisa, Pisa, Italy
    Neuroscience 239:271-9. 2013
    ....
  32. doi request reprint DHEA therapy in postmenopausal women: the need to move forward beyond the lack of evidence
    A R Genazzani
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Climacteric 13:314-6. 2010
    ....
  33. doi request reprint Selective effect of chlormadinone acetate on brain allopregnanolone and opioids content
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, 56100 Pisa, Italy
    Contraception 80:53-62. 2009
    ....
  34. ncbi request reprint Dydrogesterone increases allopregnanolone in selected brain areas and in serum of female rats
    Nicola Pluchino
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Fertil Steril 89:1384-9. 2008
    ....
  35. ncbi request reprint Androgens and the brain
    Andrea R Genazzani
    Department of Reproductive Medicine and Child Development, Section of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Maturitas 57:27-30. 2007
    ..The present short review will focus on the neuroactive effect of androgen with particular regard to the Delta4 and Delta5 androgen replacement therapy...
  36. ncbi request reprint Long-term low-dose oral administration of dehydroepiandrosterone modulates adrenal response to adrenocorticotropic hormone in early and late postmenopausal women
    Andrea R Genazzani
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 22:627-35. 2006
    ..The present study aimed to evaluate the effects of a long-term (12 months) oral DHEA administration (25 mg/day) on adrenal function, before and after 3, 6 and 12 months of treatment...
  37. ncbi request reprint Estrogen, cognition and female ageing
    Andrea Riccardo Genazzani
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Pisa, Italy
    Hum Reprod Update 13:175-87. 2007
    ..A critical update of HRT use in women and a discussion of possible prospectives for steroid use are subsequently proposed...
  38. ncbi request reprint Drospirenone increases central and peripheral beta-endorphin in ovariectomized female rats
    Andrea Riccardo Genazzani
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    Menopause 14:63-73. 2007
    ....
  39. ncbi request reprint Effect of tibolone administration on central and peripheral levels of allopregnanolone and beta-endorphin in female rats
    Andrea R Genazzani
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Italy
    Menopause 13:57-64. 2006
    ....
  40. ncbi request reprint Endocrinology of menopausal transition and its brain implications
    Andrea Riccardo Genazzani
    Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
    CNS Spectr 10:449-57. 2005
    ..These findings open new perspectives in the study of the effects of sex steroids on the central nervous system and on the possible use of alternative and/or auxiliary HRT...
  41. doi request reprint DHEA replacement for postmenopausal women: have we been looking in the right direction?
    A R Genazzani
    a Division of Gynecology and Obstetrics, University of Pisa, Italy
    Climacteric 18:669-71. 2015
    ..However, current evidence is too imprecise to draw definite conclusions. ..
  42. doi request reprint Paroxetine increases brain-derived neurotrophic factor in postmenopausal women
    Alessandra Cubeddu
    Department of Reproductive Medicine and Child Development, Division of Gynaecology and Obstetrics, University of Pisa, Pisa, Italy
    Menopause 17:338-43. 2010
    ....
  43. ncbi request reprint Comparative effects of dydrogesterone and medroxyprogesterone acetate in critical areas: the brain and the vessels
    Tommaso Simoncini
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 23:9-16. 2007
    ..The aim of the present paper is to review the comparative effects of dydrogesterone and other progestins at these sites, supporting the idea that the progestin has to be clinically selected...