Affiliation: University of Pisa
Pluchino N, Ninni F, Casarosa E, Lenzi E, Begliuomini S, Cela V, et al
. Sexually dimorphic effects of testosterone administration on brain allopregnanolone in gonadectomized rats. J Sex Med. 2008;5:2780-92 pubmed publisher
..This effect becomes particularly evident in the brain of ovariectomized animals, where the content of this specific neurosteroid is much more responsive than male animals to testosterone replacement. ..
Pluchino N, Ninni F, Casarosa E, Giannini A, Merlini S, Cubeddu A, et al
. Sex differences in brain and plasma beta-endorphin content following testosterone, dihydrotestosterone and estradiol administration to gonadectomized rats. Neuroendocrinology. 2009;89:411-23 pubmed publisher
..This effect is particularly evident in the brains of female animals where this endogenous endorphin elicits a much greater response than it does in males that have undergone gonadal steroid depletion and subsequent T replacement. ..
Pluchino N, Ninni F, Angioni S, Carmignani A, Genazzani A, Cela V. Spontaneous cornual pregnancy after homolateral salpingectomy for an earlier tubal pregnancy: a case report and literature review. J Minim Invasive Gynecol. 2009;16:208-11 pubmed publisher
Pluchino N, Cubeddu A, Begliuomini S, Merlini S, Giannini A, Bucci F, et al
. Daily variation of brain-derived neurotrophic factor and cortisol in women with normal menstrual cycles, undergoing oral contraception and in postmenopause. Hum Reprod. 2009;24:2303-9 pubmed publisher
..Interactions between BDNF, the hypothalamus-pituitary-adrenal axis and sex steroids might play a critical role in the human homeostasis and adaptation. ..