Mario Plebani

Summary

Affiliation: University Hospital
Country: Italy

Publications

  1. ncbi Charting the course of medical laboratories in a changing environment
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padua, Italy
    Clin Chim Acta 319:87-100. 2002
  2. ncbi What information on quality specifications should be communicated to clinicians, and how?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova and Center for Biomedical Research, Castelfranco Veneto TV, Azienda Ospedaliera di Padova, Via Giustiniani, 2, Padua 35128, Italy
    Clin Chim Acta 346:25-35. 2004
  3. ncbi Clinical Governance: from clinical risk management to continuous quality improvement
    Maria Laura Chiozza
    Quality Department, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:694-8. 2006
  4. ncbi Appropriateness in programs for continuous quality improvement in clinical laboratories
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Azienda Ospedaliera di Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Clin Chim Acta 333:131-9. 2003
  5. ncbi Clinical value and measurement of specific IgE
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, and Centre for Biomedical Research, Castelfranco, Veneto, Italy
    Clin Biochem 36:453-69. 2003
  6. ncbi Laboratory network of excellence: enhancing patient safety and service effectiveness
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:150-60. 2006
  7. ncbi [Acute coronary syndrome without ST-segment elevation. Current guidelines]
    Mario Plebani
    Dipartimento di Medicina di Laboratorio, Azienda Ospedaliera Università, Padova
    Recenti Prog Med 93:515-8. 2002
  8. doi Chemiluminescence and ELISA-based serum assays for diagnosing and monitoring celiac disease in children: a comparative study
    Ada Aita
    Department of Medicine DIMED, University of Padova, Padova, Italy
    Clin Chim Acta 421:202-7. 2013
  9. doi Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in children
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Clin Chem 55:150-7. 2009
  10. doi Cytokine network in rectal mucosa in perianal Crohn's disease: relations with inflammatory parameters and need for surgery
    Cesare Ruffolo
    Clinica Chirurgica 1, Department of Surgical and Gastroenterological Sciences, University of Padua, Padova, Italy
    Inflamm Bowel Dis 14:1406-12. 2008

Detail Information

Publications139 found, 100 shown here

  1. ncbi Charting the course of medical laboratories in a changing environment
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padua, Italy
    Clin Chim Acta 319:87-100. 2002
    ..The role of laboratory professionals has undergone a radical change, which calls for greater analytical accuracy, and more stringent test selection, and interpretation of results...
  2. ncbi What information on quality specifications should be communicated to clinicians, and how?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova and Center for Biomedical Research, Castelfranco Veneto TV, Azienda Ospedaliera di Padova, Via Giustiniani, 2, Padua 35128, Italy
    Clin Chim Acta 346:25-35. 2004
    ..However, the information on quality specifications that should be communicated to clinicians, and the way in which this information should be given, is still widely debated...
  3. ncbi Clinical Governance: from clinical risk management to continuous quality improvement
    Maria Laura Chiozza
    Quality Department, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:694-8. 2006
    ..It requires good multidisciplinary working and a willingness to reflect on and learn from errors to achieve a patient-centred and safer system...
  4. ncbi Appropriateness in programs for continuous quality improvement in clinical laboratories
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Azienda Ospedaliera di Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Clin Chim Acta 333:131-9. 2003
    ..Appropriateness plays a key role in programs for quality improvement...
  5. ncbi Clinical value and measurement of specific IgE
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, and Centre for Biomedical Research, Castelfranco, Veneto, Italy
    Clin Biochem 36:453-69. 2003
    ..Characterization of allergens at a molecular and submolecular level and, where necessary, the use of recombinant allergens can reduce cross-reactions and further improve the quality of immunoassays...
  6. ncbi Laboratory network of excellence: enhancing patient safety and service effectiveness
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:150-60. 2006
    ..These data should stimulate debate in the scientific community and encourage more clinical laboratories to use the same indicators to improve clinical effectiveness and clinical outcomes within the healthcare service...
  7. ncbi [Acute coronary syndrome without ST-segment elevation. Current guidelines]
    Mario Plebani
    Dipartimento di Medicina di Laboratorio, Azienda Ospedaliera Università, Padova
    Recenti Prog Med 93:515-8. 2002
    ..Powerful tests, such as cardiac troponins, on which critical decisions will rest need highly reliable methods, quality control and external quality assurance schemes...
  8. doi Chemiluminescence and ELISA-based serum assays for diagnosing and monitoring celiac disease in children: a comparative study
    Ada Aita
    Department of Medicine DIMED, University of Padova, Padova, Italy
    Clin Chim Acta 421:202-7. 2013
    ....
  9. doi Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in children
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Clin Chem 55:150-7. 2009
    ..AGA IgA II and AGA IgG II have recently been suggested as reliable tools for celiac disease (CD) diagnosis. We compared their utility for diagnosis and monitoring CD in children with that of tTG IgA, an established CD marker...
  10. doi Cytokine network in rectal mucosa in perianal Crohn's disease: relations with inflammatory parameters and need for surgery
    Cesare Ruffolo
    Clinica Chirurgica 1, Department of Surgical and Gastroenterological Sciences, University of Padua, Padova, Italy
    Inflamm Bowel Dis 14:1406-12. 2008
    ..The aim of this study was to assess the cytokine profile in the rectal mucosa of patients affected by perianal CD and to understand its relations with the systemic cytokine profile and inflammatory parameters and the need for surgery...
  11. doi Pancreatic cancer biomarkers discovery by surface-enhanced laser desorption and ionization time-of-flight mass spectrometry
    Filippo Navaglia
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Clin Chem Lab Med 47:713-23. 2009
    ..The aim of the present study was to explore the application of SELDI proteomic patterns in serum for distinguishing between cases of pancreatic cancer, chronic pancreatitis, type 2 diabetes mellitus and healthy controls...
  12. ncbi Mitochondrial DNA D-loop in pancreatic cancer: somatic mutations are epiphenomena while the germline 16519 T variant worsens metabolism and outcome
    Filippo Navaglia
    Department of Laboratory Medicine, University of Padova, Italy
    Am J Clin Pathol 126:593-601. 2006
    ....
  13. ncbi Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma
    Umberto Cillo
    Clinica Chirurgica I Dipartimento di Scienze Chirurgiche e Gastroenterologiche Università degli Studi di Padova Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy
    World J Gastroenterol 11:6920-5. 2005
    ....
  14. doi Usefulness of MALDI-TOF/MS identification of low-MW fragments in sera for the differential diagnosis of pancreatic cancer
    Andrea Padoan
    Department of Laboratory Medicine, University of Padova, Italy
    Pancreas 42:622-32. 2013
    ..To identify new biomarkers of pancreatic cancer (PaCa), we performed MALDI-TOF/MS analysis of sera from 22 controls, 51 PaCa, 37 chronic pancreatitis, 24 type II diabetes mellitus (DM), 29 gastric cancer (GC), and 24 chronic gastritis (CG)...
  15. doi Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
    ..We assessed the association of new and established cagA and vacA polymorphisms with disease...
  16. ncbi Analogs of vitamin E epitomized by alpha-tocopheryl succinate for pancreatic cancer treatment: in vitro results induce caution for in vivo applications
    Eliana Greco
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 39:662-8. 2010
    ....
  17. doi Altered intracellular calcium fluxes in pancreatic cancer induced diabetes mellitus: Relevance of the S100A8 N-terminal peptide (NT-S100A8)
    Daniela Basso
    Department of Laboratory Medicine, University of Padua, Padua, Italy
    J Cell Physiol 226:456-68. 2011
    ....
  18. doi Assessment of critical values policies in Italian institutions: comparison with the US situation
    Elisa Piva
    Department of Laboratory Medicine, University Hospital of Padua, Padua, Italy
    Clin Chem Lab Med 48:461-8. 2010
    ..Here, we report the state of critical value reporting in a large cohort of Italian laboratories and comparison with Q-Probes surveys from the College of American Pathologists as representatives of the US situation...
  19. doi TLR2 and TLR4 up-regulation and colonization of the ileal mucosa by Clostridiaceae spp. in chronic/relapsing pouchitis
    Marco Scarpa
    Oncological Surgery Unit, Veneto Institute of Oncology IOV IRCCS, Padova, Italy
    J Surg Res 169:e145-54. 2011
    ..This work examined the interplay between the microbiota adherent to the ileal pouch mucosa and the mucosal immune system in chronic/relapsing pouchitis...
  20. ncbi Multicenter evaluation of hemoglobin A1c assay on capillary electrophoresis
    Mariela Marinova
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 424:207-11. 2013
    ..Since this marker has recently been recommended as an additional tool for diagnosing diabetes, it's of the utmost importance to ensure that the precision and accuracy of HbA1c methods are satisfactory...
  21. ncbi Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause?
    Daniela Basso
    Department of Laboratory Medicine, University of Padua, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 372:120-8. 2006
    ..Our aim was to identify the pancreatic cancer diabetogenic peptide...
  22. ncbi Analytical and clinical performance of a fully automated cardiac multi-markers strategy based on protein biochip microarray technology
    Monica M Mion
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Clin Biochem 40:1245-51. 2007
    ..The analytical and clinical performance of the Evidence Cardiac Panel were evaluated...
  23. doi Serum free light chain reference values: a critical approach
    Sara Altinier
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Biochem 46:691-3. 2013
    ..The aim of the present study was to evaluate the reproducibility of FLCs immunoassay and to validate the reference range, before introducing it in routine setting...
  24. ncbi Clarithromycin resistance, tumor necrosis factor alpha gene polymorphism and mucosal inflammation affect H. pylori eradication success
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    J Gastrointest Surg 11:1506-14; discussion 1514. 2007
    ....
  25. ncbi Syngeneic living-donor liver transplantation for hemangioendothelioma: a clinical model for studying liver regeneration
    Umberto Cillo
    Clinica Chirurgica I, Dipartimento di Chirurgia Generale e Trapianti d Organo, University of Padua, School of Medicine, Padova, Italy
    Am J Transplant 5:2309-14. 2005
    ..Whether this is a potential molecular tool by means of which transplanted partial livers promote their regeneration remains to be seen in a larger number of patients...
  26. ncbi High-sensitivity C-reactive protein in umbilical cord of small-for-gestational-age neonates
    Daniele Trevisanuto
    Neonatal Intensive Care Unit, Department of Pediatrics, Medical School, University of Padova Padova Hospital, Azienda Ospedaliera, Padova, Italy
    Neonatology 91:186-9. 2007
    ..We hypothesized that the chronic inflammatory process, involved in the future atherosclerotic injury, could be found during the fetal period...
  27. ncbi Analytical and clinical evaluation of a new heart-type fatty acid-binding protein automated assay
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:1383-5. 2006
    ..Heart-type fatty acid-binding protein (H-FABP) appears to be one of the best candidates among the new early cardiac markers studied...
  28. doi Recent advances in diagnostic technologies for autoimmune diseases
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Autoimmun Rev 8:238-43. 2009
    ....
  29. ncbi Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    Clin Chim Acta 357:184-9. 2005
    ..Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere with both beta-cell function and liver and muscle glucose metabolism...
  30. doi Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Cell Commun Signal 12:20. 2014
    ..NF-κB, Akt and mTOR pathways, Cai2+ and EMT were studied in well (Capan1 and BxPC3) and poorly differentiated (Panc1 and MiaPaCa2) cell lines...
  31. ncbi Precision performance at low levels and 99th percentile concentration of the Access AccuTnl assay on two different platforms
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 47:367-71. 2009
    ....
  32. doi Pancreatic cancer alters human CD4+ T lymphocyte function: a piece in the immune evasion puzzle
    Paola Fogar
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 40:1131-7. 2011
    ....
  33. doi Differentiation of cardiac and noncardiac dyspnea using bioelectrical impedance vector analysis (BIVA)
    Antonio Piccoli
    Department of Medicine, University of Padova, Padova, Italy
    J Card Fail 18:226-32. 2012
    ..We sought to determine whether a relationship exists between ultrasound detection of lung congestion, NT-proBNP, and BIVA in patients with acute dyspnea...
  34. doi The brain-to-brain loop concept for laboratory testing 40 years after its introduction
    Mario Plebani
    Department of Laboratory Medicine, University of Padova, Italy
    Am J Clin Pathol 136:829-33. 2011
    ..This review describes the changes and their implications for analysis of errors associated with laboratory testing...
  35. doi VKORC1, CYP2C9 and CYP4F2 genetic-based algorithm for warfarin dosing: an Italian retrospective study
    Carlo Federico Zambon
    Department of Laboratory Medicine, University Hospital of Padua, 35128 Padua, Italy
    Pharmacogenomics 12:15-25. 2011
    ..A total of 371 patients under stable warfarin therapy were retrospectively selected to develop a pharmacogenetic algorithm to identify the individual maintenance dose...
  36. ncbi Innotrac Aio!: a point-of-care or a routine analyzer? Analytical performance and plasma/whole blood comparison
    Sara Altinier
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:1278-82. 2006
    ....
  37. doi Determinants of circulating asymmetric and symmetric dimethylarginines in patients evaluated for acute dyspnea
    Marta Codognotto
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Clin Chem Lab Med 49:237-42. 2011
    ..The relationship between asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) plasma concentrations and acute heart failure is unknown. We evaluated ADMA and SDMA in patients with acute dyspnea...
  38. doi PATHFAST NT-proBNP (N-terminal-pro B type natriuretic peptide): a multicenter evaluation of a new point-of-care assay
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 48:1029-34. 2010
    ..These biomarkers have proven to be of particular value in the management of chronic and acute heart failure patients, and in the outpatient and the emergency setting...
  39. doi New screening tests enrich anti-transglutaminase results and support a highly sensitive two-test based strategy for celiac disease diagnosis
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Clin Chim Acta 412:1662-7. 2011
    ..We compared the diagnostic accuracy of three new tests proposed for CD screening with that of the well established IgA tTG, and ascertained whether any combination of these tools might enhance accuracy in diagnosing CD...
  40. ncbi Decreased total lymphocyte counts in pancreatic cancer: an index of adverse outcome
    Paola Fogar
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Pancreas 32:22-8. 2006
    ..Our aim was to ascertain whether the immunophenotype pattern of blood lymphocytes in PC correlates with tumor stage, grade, or survival...
  41. doi Celiac disease in North Italian patients with autoimmune thyroid diseases
    Aglaura Cinzia Spadaccino
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Autoimmunity 41:116-21. 2008
    ..An IgA deficiency is the most frequent immunodeficiency in humans and, in general, high frequency of this disorder was demonstrated in those with autoimmune diseases...
  42. ncbi Time to reconsider the clinical value of immunoglobulin G4 to foods?
    Daniela Bernardi
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 46:687-90. 2008
    ..The usefulness of serum antibodies to common food antigens (immunoglobulin G4; IgG4) assay in management of patients suffering from food intolerance was assessed...
  43. pmc Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study
    Daniela Basso
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 8:e54824. 2013
    ....
  44. ncbi Suicide gene therapy with the yeast fusion gene cytosine deaminase/uracil phosphoribosyltransferase is not enough for pancreatic cancer
    Paola Fogar
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Pancreas 35:224-31. 2007
    ..We ascertained whether gene therapy with FCY1-FUR1 is effective in killing pancreatic cancer cells after 5-fluorocytosine (5-FC) treatment...
  45. ncbi Identification and quantification of hemoglobins in whole blood: the analytical and organizational aspects of Capillarys 2 Flex Piercing compared with agarose electrophoresis and HPLC methods
    Sara Altinier
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2 35128 Padova, Italy
    Clin Chem Lab Med 51:791-7. 2013
    ..The present study was conducted to evaluate the analytical performance and the organizational aspects of Capillarys 2 Flex Piercing system (CFP) respect to agarose electrophoresis and HPLC methods in hemoglobinopathies screening...
  46. doi Effectiveness of the combined evaluation of KLK3 genetics and free-to-total prostate specific antigen ratio for prostate cancer diagnosis
    Carlo Federico Zambon
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    J Urol 188:1124-30. 2012
    ..We ascertained whether the knowledge of KLK3 genetics would enhance prostate specific antigen diagnostic performance in patients with clinical suspicion of prostate cancer...
  47. ncbi External Quality Assessment: an effective tool for Clinical Governance in laboratory medicine
    Laura Sciacovelli
    Centre of Biomedical Research, Civil Hospital, Castelfranco Veneto TV, and Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 44:740-9. 2006
    ..The main aim of the activities of an EQAP in Laboratory Medicine is to sustain improvements in the quality of services provided by participating laboratories for the benefit of patients...
  48. ncbi New biochemical markers: from bench to bedside
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 381:14-20. 2007
    ..However, patients with normal troponin values are not necessarily risk-free for major cardiac events...
  49. doi The "hospital central laboratory": automation, integration and clinical usefulness
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 48:911-7. 2010
    ..In conclusion, in laboratory medicine, technology represents a tool for improving clinical effectiveness and patient outcomes, but it has to be managed by qualified laboratory professionals...
  50. ncbi Biological variability of lymphocyte subsets of human adults' blood
    Francesca Tosato
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova PD, Italy Electronic address
    Clin Chim Acta 424:159-63. 2013
    ....
  51. ncbi An IgE multiple myeloma: contradictory findings in clinical laboratory testing
    Sara Altinier
    Department of Laboratory Medicine, University Hospital of Padova, Italy Electronic address
    Clin Chim Acta 425:114-6. 2013
    ..In the present paper it is described a case of IgE myeloma where contradictory findings between immunometric and separative techniques were found...
  52. ncbi DNA repair pathways and mitochondrial DNA mutations in gastrointestinal carcinogenesis
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 381:50-5. 2007
    ....
  53. pmc Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo
    Paolo Tessari
    Metabolism Division, Department of Medicine, University of Padova, Padova, Italy
    Diabetes 62:2699-708. 2013
    ..We conclude that whole-body NOx production is decreased in aging and T2DM. Age, ADMA concentration, and T2DM, but not insulin resistance, appear as negative regulators of whole-body NOx production. ..
  54. doi Effects of sample transportation on commonly requested laboratory tests
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 50:1755-60. 2012
    ..The aim of the present study was to evaluate the effects of an integrated system for sample transportation on the quality of six laboratory parameters considered representative of the quality of all tests requested and performed...
  55. doi Does POCT reduce the risk of error in laboratory testing?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chim Acta 404:59-64. 2009
    ..There is therefore an urgent need for an evaluation of errors and risks of error in POCT that is based on the entire testing process and uses well-designed studies aiming to improve clinical outcomes and increase patient safety...
  56. doi Post-analytical errors with portable glucose meters in the hospital setting
    Paolo Carraro
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 404:65-7. 2009
    ..2% of results. Although in the post-analytical phase the frequency of incomplete or incorrect data was high, no adverse events were found to be related to this type of error...
  57. ncbi In vivo and in vitro allergy diagnostics: it's time to re-appraise the costs
    Franco Borghesan
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 45:391-5. 2007
    ..The aim of the present paper is to evaluate the relevance of component-resolved in vitro diagnosis in comparison to extract-based diagnosis and the relative global costs in relation to clinical outcomes...
  58. doi Evaluation of effectiveness of a computerized notification system for reporting critical values
    Elisa Piva
    Department of Laboratory Medicine, Padua University School of Medicine, Padua, Italy
    Am J Clin Pathol 131:432-41. 2009
    ..The communication also improves the likelihood of reaching the physician on call and may provide important decision support...
  59. doi The IFCC Working Group on laboratory errors and patient safety
    Laura Sciacovelli
    Center of Biomedical Research, Castelfranco Veneto TV, Italy
    Clin Chim Acta 404:79-85. 2009
    ..The mission of the WG-LEPS is to promote and encourage investigations into errors in laboratory medicine, collect data available on this issue and recommend strategies and procedures for improving patient safety...
  60. ncbi A new indirect chemiluminescent immunoassay to measure anti-tissue transglutaminase antibodies
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    J Pediatr Gastroenterol Nutr 43:613-8. 2006
    ..p.A., Saluggia, Italy) in diagnosing and monitoring CD in children...
  61. ncbi Errors in clinical laboratories or errors in laboratory medicine?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova and Center of Biomedical Research, Castelfranco Veneto, Italy
    Clin Chem Lab Med 44:750-9. 2006
    ..In a modern approach to total quality, centered on patients' needs and satisfaction, the risk of errors and mistakes in pre- and post-examination steps must be minimized to guarantee the total quality of laboratory services...
  62. ncbi Immunosuppressant therapeutic drug monitoring by LC-MS/MS: workflow optimization through automated processing of whole blood samples
    Mariela Marinova
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Biochem 46:1723-7. 2013
    ..The aim of the present study was therefore to develop an automated sample-preparation protocol for the quantification of sirolimus, everolimus and tacrolimus by LC-MS/MS using a liquid handling platform...
  63. pmc Molecular refinement of clinical staging in hepatocellular carcinoma patients evaluated for potentially curative therapies
    Alessandro Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento di Chirurgia Generale e Trapianti d Organo, Universita di Padova, Padova, Italy
    PLoS ONE 6:e23093. 2011
    ..VEGF and AFP mRNA determinations in the blood are promising prognostic factors for patients with HCC. This study explores their potential prognostic synergy in a cohort of HCC patients evaluated for potentially curative therapies...
  64. doi Harmonization in laboratory medicine: the complete picture
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padua, 35128 Padua, Italy
    Clin Chem Lab Med 51:741-51. 2013
    ....
  65. ncbi Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes
    Michele Dalla Vestra
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    J Am Soc Nephrol 16:S78-82. 2005
    ..25 P < 0.05). In conclusion, this study demonstrates that acute-phase markers of inflammation are associated with nephropathy status and GBM thickening, suggesting a role for inflammation in the pathogenesis of diabetic glomerulopathy...
  66. doi Monoclonal gammopathy after liver transplantation: a risk factor for long-term medical complications other than malignancies
    Alessandra Galioto
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Transpl Int 25:25-33. 2012
    ..Permanent MGUS after LT does not entail a significant risk of malignancy, but it is associated with a higher risk of serious infections and CKD...
  67. ncbi External quality assessment for biochemical markers of myocardial damage: an Italian experience
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 42:1434-41. 2004
    ..The findings demonstrate that participation in EQA schemes provided an opportunity for participating laboratories to continuously improve the quality of their services...
  68. ncbi Requirements for improving quality in the measurement of bone markers
    Daniela Bernardi
    Department of Laboratory Medicine, University Hospital of Padua, Padua, Italy
    Clin Chim Acta 346:79-86. 2004
    ..The aim of the present study was to define quality specifications of bone markers measurement in the total testing process...
  69. ncbi Quality control in coagulation testing
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Semin Thromb Hemost 34:642-6. 2008
    ..New challenges to EQA schemes for coagulation testing derive from the introduction of innovative tests, genetic analysis, and the need to assess not only analytical procedures but also all steps included in the total testing process...
  70. pmc Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death
    Elena Favaro
    Department of Oncology and Surgical Sciences, Oncology Section, University of Padova, Padova, Italy
    Am J Pathol 173:1186-201. 2008
    ....
  71. doi Exploring the iceberg of errors in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 404:16-23. 2009
    ..The lesson we have learned is that each practice must examine its own total testing process to discover its weaknesses and identify appropriate remedies...
  72. doi High-throughput LC-MS/MS method for monitoring sirolimus and everolimus in the routine clinical laboratory
    Mariela Ivanova
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 49:1151-8. 2011
    ....
  73. ncbi The C-reactive protein levels in left ventricular dysfunction of different etiology
    Dinko Anzulović-Mirosević
    Department of Cardiology, University of Padova Medical School, Padova, Italy
    Inflamm Allergy Drug Targets 8:247-51. 2009
    ..We have investigated variations in the C-reactive protein levels in groups of patients with left ventricular dysfunction of various causes...
  74. doi Anti-ganglioside autoantibodies in type 1 diabetes
    Marta Lucchetta
    Department of Neurosciences, 35128 University of Padova, Via Giustiniani, 5, Padova, Italy
    Muscle Nerve 41:50-3. 2010
    ..The higher prevalence of antibodies in diabetic patients compared to controls may reflect the common pattern of antigens shared by peripheral nerve and pancreatic islet cells...
  75. doi Diagnosis of iron deficiency in patients undergoing hemodialysis
    Mauro Buttarello
    Dept of Laboratory Medicine, University Hospital of Padova, Via Giustiniani, Padua, Italy
    Am J Clin Pathol 133:949-54. 2010
    ..72 for HYPO% and 0.68 for %Hypo-He; best cutoff values, 5.8 and 2.7, respectively). The newly proposed Ret-He and %Hypo-He can provide clinicians with information equivalent to CHret and HYPO%...
  76. doi Mass spectrometry measurement of plasma hepcidin for the prediction of iron overload
    Annarosa Floreani
    Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
    Clin Chem Lab Med 49:197-206. 2011
    ..The aims of the study were 1) to assess the performance of this method in different conditions of iron metabolism disorders; 2) to assess the diagnostic validity of non-invasive serum biomarkers in the identification of iron overload...
  77. doi Interpretative reports and critical values
    Elisa Piva
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chim Acta 404:52-8. 2009
    ..Clinical laboratories can therefore work to improve clinical effectiveness, without forgetting that everything should be designed to provide the best outcomes for patients...
  78. doi Evaluation of erythrocyte band 3 phosphotyrosine level, glutathione content, CA-125, and human epididymal secretory protein E4 as combined parameters in endometriosis
    Luciana Bordin
    Department of Biological Chemistry, University of Padova, Padova, Italy
    Fertil Steril 94:1616-21. 2010
    ....
  79. ncbi Errors in a stat laboratory: types and frequencies 10 years later
    Paolo Carraro
    Department of Laboratory Medicine, Azienda Ospedaliera Università and Azienda ULSS 16, Padova, Italy
    Clin Chem 53:1338-42. 2007
    ....
  80. ncbi Research translation: a new frontier for clinical laboratories
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, and Center of Biomedical Research, Castelfranco Veneto TV, Italy
    Clin Chem Lab Med 44:1303-12. 2006
    ....
  81. ncbi Measurement of serum monoclonal components: comparison between densitometry and capillary zone electrophoresis
    Michele Mussap
    Department of Laboratory Medicine, University Hospital Padua, Via Nicolò Giustiniani 2, 35128 Padua, Italy
    Clin Chem Lab Med 44:609-11. 2006
    ..In conclusion, to compare previous results obtained by M-protein densitometric scanning with those obtained by direct measurement of CZE peaks, the calculation of a univocal transforming factor appears to be unreliable...
  82. ncbi NT-proBNP in the differential diagnosis of acute dyspnea in the emergency department
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Biochem 38:1041-4. 2005
    ..The purpose of this study was to verify the usefulness of NT-proBNP in the differential diagnosis of dyspnea in a population of patients presenting in the ER with breathlessness...
  83. ncbi Heterophilic antibody interference in a non-endogenous molecule assay: an apparent elevation in the tacrolimus concentration
    Sara Altinier
    Department of Laboratory Medicine University Hospital of Padova, Italy
    Clin Chim Acta 402:193-5. 2009
    ..In the present paper a heterophilic antibody interference in the tacrolimus measurement is described...
  84. doi An expert system for the classification of serum protein electrophoresis patterns
    Sara Altinier
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 46:1458-63. 2008
    ..The aim of this work was to evaluate Neurosoft-Sebia, an expert system developed to discriminate between regular and anomalous serum protein electrophoresis patterns performed on Capillarys2...
  85. doi Quality Indicators in Laboratory Medicine: from theory to practice. Preliminary data from the IFCC Working Group Project "Laboratory Errors and Patient Safety"
    Laura Sciacovelli
    Department of Laboratory Medicine and Center of Biomedical Research, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 49:835-44. 2011
    ....
  86. doi Automated reticulocyte counting: state of the art and clinical applications in the evaluation of erythropoiesis
    Elisa Piva
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 48:1369-80. 2010
    ..In the absence of better laboratory standardization, having a single reference range for the parameters provided by flow-cytometric studies of reticulocytes remains problematic...
  87. doi Pathogenesis of Helicobacter pylori infection
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, Padua, Italy
    Helicobacter 15:14-20. 2010
    ..Among those are studies on the genetic variation of genes encoding outer membrane proteins and the mimicry of host antigens, factors that alter host-cell metabolism and factors that modulate the host's immune response...
  88. doi Interpretative commenting: a tool for improving the laboratory-clinical interface
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chim Acta 404:46-51. 2009
    ..Moreover, quality assurance programs and an appropriate clinical audit are required to evaluate and improve upon this activity...
  89. ncbi Continuing medical education: a challenge to the Italian Scientific Societies of Laboratory Medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padua, Italy
    Clin Chim Acta 319:161-7. 2002
    ..In Italy, a program for continuing education in medicine (Educazione Continua in Medicina (ECM)) has recently been promoted by the National Government...
  90. ncbi Errors in laboratory medicine and patient safety: the road ahead
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova and Center for Biomedical Research, Castelfranco Veneto, Italy
    Clin Chem Lab Med 45:700-7. 2007
    ..Moreover, a fundamental shift in improving patient safety in laboratory medicine is to move from error reporting to risk management...
  91. doi Evaluating laboratory diagnostic tests and translational research
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 48:983-8. 2010
    ....
  92. ncbi Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels
    Lucio Marchioro
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 42:543-8. 2004
    ..The results were positive for both screening methods, confirming the efficacy of two simultaneous methods with different cut-off levels...
  93. doi Respiratory allergy to lipid transfer protein
    Franco Borghesan
    Dipartimento di Medicina di Laboratorio, Padova, Italy
    Int Arch Allergy Immunol 147:161-5. 2008
    ..Due to unclear reasons, allergy to lipid transfer protein (LTP) is frequent in Mediterranean countries but rare in Northern Europe...
  94. ncbi Automated blood cell counts: state of the art
    Mauro Buttarello
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Am J Clin Pathol 130:104-16. 2008
    ....
  95. doi The detection and prevention of errors in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Ann Clin Biochem 47:101-10. 2010
    ....
  96. ncbi Anti-heparan sulphate antibodies and homocysteine in dementia: markers of vascular pathology?
    Chiara Briani
    Department of Neurosciences, University of Padova, Via Giustiniani, 5, 35128 Padova, Italy
    J Neurol Sci 229:215-8. 2005
    ..2% of patients with other neurological diseases. The present findings suggest that neither elevated HS Abs titres nor increased homocysteinemia may represent a useful biochemical marker for the diagnosis of VD...
  97. ncbi A new turbidimetric standard to improve the quality assurance of the erythrocyte sedimentation rate measurement
    Elisa Piva
    Dipartimento di Medicina di Laboratorio, Universita degli Studi di Padova, Azienda Ospedaliera di Padova, Padova, Italy
    Clin Biochem 40:491-5. 2007
    ..According to this point of view, the ESR would seem a semi-quantitative test instead of a real hematological test with any clinical importance. The new millennium has consolidated ESR automation and a QC plan cannot be postponed...
  98. ncbi The changing scenario in laboratory medicine and the role of laboratory professionals in translational medicine
    Mario Plebani
    Department of Laboratory Medicine, Azienda Ospedaliera Universita di Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Clin Chim Acta 393:23-6. 2008
    ....
  99. ncbi Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease
    Marco Scarpa
    Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padova, Padova, Italy
    Dis Colon Rectum 50:861-9. 2007
    ..This study was designed to assess the role of fecal lactoferrin and calprotectin as markers of intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection...
  100. ncbi Erythrocyte sedimentation rate: use of fresh blood for quality control
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padua, Padova, Italy
    Am J Clin Pathol 117:621-6. 2002
    ..Finally, to monitor analytic performance, a comparison was made between results from the measurement of ESR in specimens stored at 4 degrees C for 24 hours and results obtained in fresh samples...
  101. ncbi Quality specifications: self pleasure for clinical laboratories or added value for patient management?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 45:462-6. 2007
    ..A consensus should be achieved in the scientific community on these issues to assure better utilization of laboratory data and, ultimately, improved clinical outcomes...