Research Topics
Species | Matteo PirroSummaryAffiliation: University of Perugia Country: Italy Publications
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Detail Information
Publications
Association between circulating osteoprogenitor cell numbers and bone mineral density in postmenopausal osteoporosisM Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1 06129 Perugia, Italy
Osteoporos Int 21:297-306. 2010..Conversely, the increased number of alkaline phosphatase/CD34-positive cells may reflect the reactive bone marrow contribution to bone formation...
Association between thyroid hormone levels, the number of circulating osteoprogenitor cells, and bone mineral density in euthyroid postmenopausal womenMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Metabolism 61:569-76. 2012..Exposure of CD34+ cells to physiological triiodothyronine concentrations stimulates mineralization in vitro...
Circulating immature osteoprogenitor cells and arterial stiffening in postmenopausal osteoporosisM Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini 1, Perugia, Italy
Nutr Metab Cardiovasc Dis 21:636-42. 2011..We investigated whether an increased number of circulating OPCs underlies the association of osteoporosis with arterial stiffness...
High weight or body mass index increase the risk of vertebral fractures in postmenopausal osteoporotic womenMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini 1, 06129 Perugia, Italy
J Bone Miner Metab 28:88-93. 2010..In conclusion, among postmenopausal women with osteoporosis, body weight and BMI are associated with a higher likelihood of having a vertebral fracture, irrespective of the positive association between weight and BMD...
Low-grade systemic inflammation impairs arterial stiffness in newly diagnosed hypercholesterolaemiaM Pirro
University of Perugia, Perugia, Italy
Eur J Clin Invest 34:335-41. 2004....
Attenuation of inflammation with short-term dietary intervention is associated with a reduction of arterial stiffness in subjects with hypercholesterolaemiaMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Eur J Cardiovasc Prev Rehabil 11:497-502. 2004..Whether mitigation of low-grade systemic inflammation, through a low-cholesterol/low-saturated fat diet, may have a role in improving arterial stiffness is still untested...
Cardiovascular risk factors and recommended lipid goals attainment among patients referred in a tertiary care lipid clinicMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, and Hospital Santa Maria della Misericordia, Piazzale Menghini, Perugia, Italy
Eur J Intern Med 22:412-7. 2011..We investigated the burden of cardiovascular risk and the distance of lipid fractions from the recommended targets by statin therapy and risk status in patients referred to a tertiary care lipid clinic...
Increased ratio of CD31+/CD42- microparticles to endothelial progenitors as a novel marker of atherosclerosis in hypercholesterolemiaMatteo Pirro
Department of Clinical and Experimental Medicine, University of Perugia, Italy
Arterioscler Thromb Vasc Biol 26:2530-5. 2006..We also studied the in vitro effect of microparticles from hypercholesterolemic patients on endothelial progenitor survival...
Microparticles derived from endothelial progenitor cells in patients at different cardiovascular riskMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Atherosclerosis 197:757-67. 2008..We also investigated the relationship of EPCs-derived microparticles to cardiovascular risk factors and aortic stiffness, a marker of cardiovascular risk and impaired vascular repair by EPCs...
Influence of short-term rosuvastatin therapy on endothelial progenitor cells and endothelial functionMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Cardiovasc Pharmacol Ther 14:14-21. 2009....
Reduced number of circulating endothelial progenitors and HOXA9 expression in CD34+ cells of hypertensive patientsMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Hypertens 25:2093-9. 2007..The objective of our study was to measure the expression of HOXA9 in CD34+ cells from hypertensive patients and to investigate its correlation with the number of circulating EPCs...
Hypercholesterolemia-associated endothelial progenitor cell dysfunctionMatteo Pirro
Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita degli Studi di Perugia, Ospedale S Maria della Misericordia, Perugia, Italy
Ther Adv Cardiovasc Dis 2:329-39. 2008....
Preclinical vascular damage in white postmenopausal women: the relevance of osteoprotegerinDonatella Siepi
Unit of Internal Medicine, Angiology and Atherosclerosis, Ospedale S Maria della Misericordia University of Perugia, Piazzale Menghini, 1 06129 Perugia, Italy
Metabolism 57:321-5. 2008..On this basis, we could speculate that OPG levels may be considered not a cardiovascular risk condition but a defense against atherosclerotic progression...
Ambulatory arterial stiffness index is not a specific marker of reduced arterial complianceGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Hypertension 49:986-91. 2007....
Early vascular damage in primary hypoalphalipoproteinemiaGaetano Vaudo
Department of Internal Medicine, Angiology, and Atherosclerosis, University of Perugia, Perugia, Italy
Metabolism 52:328-32. 2003..45 and -0.49, respectively; both P <.05). In conclusion, subjects with primary hypoalpha, without overt cardiovascular disease, are characterized by an impaired endothelial function and by an increase in large-artery IMT...
Effects of rosuvastatin on 3-nitrotyrosine and aortic stiffness in hypercholesterolemiaMatteo Pirro
Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale R Silvestrini, S Andrea delle Fratte, 06100 Perugia, Italy
Nutr Metab Cardiovasc Dis 17:436-41. 2007..The aim of the present study was to investigate the short-term effect of cholesterol lowering with rosuvastatin on 3-nitrotyrosine (3-NT), a marker of peroxynitrite-mediated oxidative stress, and on arterial stiffness...
Simvastatin increases bone mineral density in hypercholesterolemic postmenopausal womenGraziana Lupattelli
Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of, Perugia, Italy
Metabolism 53:744-8. 2004..860 +/- 0.110 v 0.853 +/- 0.096 and 0.847 +/- 0.095; P <.05). In conclusion, as partly suggested by retrospective or observational data, this longitudinal study indicates that simvastatin treatment exerts a beneficial effect on BMD...
Metabolic syndrome is associated with aortic stiffness in untreated essential hypertensionGiuseppe Schillaci
University of Perugia, Perugia, Italy
Hypertension 45:1078-82. 2005..Central, but not general, adiposity is an important determinant of aortic stiffness in hypertension...
Age-specific relationship of aortic pulse wave velocity with left ventricular geometry and function in hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, IT 06129 Perugia, Italy
Hypertension 49:317-21. 2007..With increasing age, a relationship between aortic PWV (as a measure of arterial stiffness) and left ventricular concentric geometry emerges, which ultimately leads to a depressed ventricular systolic function...
Relevance of homocysteine on brachial flow-mediated vasodilatation and carotid and femoral intima-media thickness in patients with hypercholesterolemiaGaetano Vaudo
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia School of Medicine, Via Brunamonti 51, 06122 Perugia, Italy
Am J Cardiol 93:1413-6, A9. 2004..Homocysteine levels seem to be an additional factor in the initial atherosclerotic damage of patients with hypercholesterolemia...
Increased C-reactive protein concentrations in never-treated hypertension: the role of systolic and pulse pressuresGiuseppe Schillaci
Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Policlinico Monteluce, Universita degli Studi di Perugia, Via B Brunamonti 51, 06122 Perugia, Italy
J Hypertens 21:1841-6. 2003....
Direct association between high-density lipoprotein cholesterol and endothelial function in hyperlipemiaGraziana Lupattelli
Unit of Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Am J Cardiol 90:648-50. 2002
Relation between renal function within the normal range and central and peripheral arterial stiffness in hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Hypertension 48:616-21. 2006..These relations are in part independent from the effect of several confounders, including age, sex, and blood pressure values...
Different impact of the metabolic syndrome on left ventricular structure and function in hypertensive men and womenGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Hypertension 47:881-6. 2006..The effect of MS is more pronounced in women and is partly independent from the effect of several hemodynamic and nonhemodynamic determinants of LV mass...
Mechanisms of high-density lipoprotein cholesterol effects on the endothelial function in hyperlipemiaGraziana Lupattelli
Department of Clinical and Experimental Medicine, University of Perugia, Italy
Metabolism 52:1191-5. 2003..05). Our data suggest that in hyperlipemic subjects free of cardiovascular disease low HDL-c negatively modulates endothelial function through a lack of oxidation inhibition and a concomitant overexpression of adhesion molecules...
Aortic stiffness in untreated adult patients with human immunodeficiency virus infectionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Hypertension 52:308-13. 2008..PWV increases with increasing serum gamma-glutamyl transpeptidase concentration. Our data support the hypothesis that HIV infection is a risk factor for arteriosclerosis...
Paraoxonase-1 activity modulates endothelial function in patients with peripheral arterial diseaseLeonella Pasqualini
Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Atherosclerosis 183:349-54. 2005..40, p=0.008), brachial-artery diameter (beta=-0.39, p=0.01) and male sex (beta=-0.27, p=0.04). These finding support the importance of PON1 activity as a modulating factor of the endothelial function...
Plasma C-reactive protein in subjects with hypo/hyperalphalipoproteinemiasMatteo Pirro
Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Italy
Metabolism 52:432-6. 2003..In conclusion, in subjects with Hypo-A or Hyper-A, HDL-C levels may account for plasma CRP variations independent of other potential cardiovascular risk factors...
Human endothelial impairment in sepsisGaetano Vaudo
Internal Medicine, Angiology and Atherosclerosis University of Perugia, S Maria della Misericordia Hospital Piazzale Menghini, 1, 06129 Perugia, Italy
Atherosclerosis 197:747-52. 2008....
Large-artery stiffness: a reversible marker of cardiovascular risk in primary hyperparathyroidismGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Atherosclerosis 218:96-101. 2011..We investigated whether aortic stiffness, an early marker of arteriosclerosis and a strong predictor of cardiovascular risk, is increased in pHPT, and whether it improves after parathyroidectomy...
Prognostic value of elevated white blood cell count in hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Perugia, Italy
Am J Hypertens 20:364-9. 2007..However, as yet the prognostic significance of white blood cell (WBC) count in the setting of uncomplicated hypertension has not been investigated...
Cholesterol metabolism differs after statin therapy according to the type of hyperlipemiaGraziana Lupattelli
Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Italy
Life Sci 90:846-50. 2012..Common hyperlipemias have shown different patterns of cholesterol metabolism. We evaluated whether cholesterol absorption and synthesis may differ after statin therapy in primary hyperlipemias...
Effect of body weight changes on 24-hour blood pressure and left ventricular mass in hypertension: a 4-year follow-upGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Via Brunamonti 51, 06122 Perugia, Italy
Am J Hypertens 16:634-9. 2003..Few data are available on the long-term effects of weight loss on 24-h blood pressure (BP) and left ventricular mass in overweight hypertensive patients...
Plasma viscosity in isolated systolic hypertension: the role of pulse pressureGiovanni Ciuffetti
Unit of Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Am J Hypertens 18:1005-8. 2005..Systolic BP and PP appear to be major determinants of PV levels in these patients, independent of the potential proinflammatory action of traditional cardiovascular risk factors...
Metabolic syndrome and preclinical atherosclerosis: focus on femoral arteriesGaetano Vaudo
Internal Medicine, Angiology and Atherosclerosis, University of Perugia School of Medicine, S Maria della Misericordia Hospital, Piazzale Menghini, 1, 06100, Italy
Metabolism 56:541-6. 2007..Moreover, it focused on the strong influence of metabolic syndrome on preclinical atherosclerotic lesions at the femoral site...
Anti-tumor necrosis factor-alpha response in rheumatoid arthritis is associated with an increase in serum soluble CD30Roberto Gerli
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Rheumatol 35:14-9. 2008..To verify the contribution of this T cell subset to disease remission, sCD30 levels were analyzed longitudinally in patients with active RA following infliximab therapy...
Prognostic significance of isolated, non-specific left ventricular repolarization abnormalities in hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
J Hypertens 22:407-14. 2004..The aim of this study was to investigate the prognostic significance of such changes...
Prognostic value of low and high ankle-brachial index in hospitalized medical patientsLeonella Pasqualini
Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Eur J Intern Med 23:240-4. 2012..The ankle-brachial pressure index (ABI) represents a noninvasive, objective tool to diagnose PAD and to predict adverse outcome...
Prognostic impact of prolonged ventricular repolarization in hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, 06132 Perugia, Italy
Arch Intern Med 166:909-13. 2006..QT interval prolongation on the surface electrocardiogram (ECG) predicts cardiovascular complications in high-risk subjects, but its prognostic role in uncomplicated hypertension has been understudied...
Prostaglandin E1 improves endothelial function in critical limb ischemiaSimona Marchesi
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Via Brunacci Brunamonti, 51 IT 06122 Perugia, Italy
J Cardiovasc Pharmacol 41:249-53. 2003..0 +/- 1.1% to 3.1 +/- 0.6% and 5.2 +/- 2.1%, both p < 0.05). In conclusion, treatment with PGE1 determines a significant improvement in endothelial function in patients with critical limb ischemia...
Aortic stiffness is increased in polymyalgia rheumatica and improves after steroid treatmentGiuseppe Schillaci
Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita degli Studi di Perugia, Ospedale S Maria della Misericordia piazzale G Menghini, 1 06129 Perugia, Italy
Ann Rheum Dis 71:1151-6. 2012..A study was undertaken to investigate whether aortic stiffness is increased in PMR and whether it improves after steroid treatment...
Osteoanabolic therapy: a non-surgical option of treatment for Kümmell's disease?Gianluigi Fabbriciani
Institute of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Piazzale Menghini, 1, 06129 Perugia, Italy
Rheumatol Int 32:1371-4. 2012..Moreover in this condition, osteoanabolic treatment may be used in patients with Kümmell's disease to enhance vertebral fracture's healing and contribute to back pain relief...
Increased postprandial lipemia in patients with normolipemic peripheral arterial diseaseGraziana Lupattelli
Internal Medicine, Angiology, and Atherosclerosis Unit, Department of Clinical and Experimental Medicine, University of Perugia, Italy
Am Heart J 143:733-8. 2002....
Adiponectin and hypertension: the connection lies within the fatGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis Disease, University of Perugia, Hospital S. Maria della Misericordia, Perugia, Italy
Am J Hypertens 21:374-5. 2008
Combined effects of office and 24-h blood pressure on aortic stiffness in human hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, IT 06129 Perugia, Italy
J Hypertens 29:869-75. 2011..Office BP may not always reflect BP behaviour away from the medical environment, and it is uncertain whether office or out-of-office BP values are stronger determinants of arterial stiffness...
Prognostic value of treatment-induced changes in twenty-four-hour mean and pulse pressures in adult hypertensive patientsGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Am J Cardiol 90:896-9. 2002
Prognostic value of the metabolic syndrome in essential hypertensionGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
J Am Coll Cardiol 43:1817-22. 2004..We sought to determine the prognostic significance of the metabolic syndrome in hypertension...
Transient osteoporosis of the hip: successful treatment with teriparatideGianluigi Fabbriciani
Institute of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Rheumatol Int 32:1367-70. 2012..Disappearance of the symptoms and normalization of MRI were obtained...
Visceral fat positively correlates with cholesterol synthesis in dyslipidaemic patientsGraziana Lupattelli
Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Italy
Eur J Clin Invest 42:164-70. 2012....
Endothelial microparticles and arterial stiffness: casual coincidence or causative culprit?Giuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Am J Hypertens 20:965-6. 2007
Impact of treatment with protease inhibitors on aortic stiffness in adult patients with human immunodeficiency virus infectionGiuseppe Schillaci
Unit of Internal Medicine, Angiology, and Arteriosclerosis, University of Perugia, Italy
Arterioscler Thromb Vasc Biol 25:2381-5. 2005..We hypothesized that aortic stiffness, an early marker of arteriosclerosis, may be increased in HIV patients treated with protease inhibitors...
CD4+CD28- T lymphocytes contribute to early atherosclerotic damage in rheumatoid arthritis patientsRoberto Gerli
Center for the Study of Rheumatic Diseases, Section of Internal Medicine and Oncological Sciences, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico di Monteluce, I 06122 Perugia, Italy
Circulation 109:2744-8. 2004..However, the potential association between CD4+CD28null T cells and early atherosclerotic changes in RA has never been investigated...
Association of Parathyroid Hormone and 25-OH-Vitamin D Levels with Arterial Stiffness in Postmenopausal Women with Vitamin D InsufficiencyMatteo Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia
J Atheroscler Thromb 19:924-31. 2012..PTH accounted for the association between 25-OH-vitamin D levels and aortic stiffness...
C-reactive protein in hypertension: clinical significance and predictive valueGiuseppe Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis Disease, University of Perugia Medical School, Hospital S Maria della Misericordia, Piazzale Menghini, 1, IT 06132 Perugia, Italy
Nutr Metab Cardiovasc Dis 16:500-8. 2006..In this review, various aspects of the pathogenesis of inflammation in hypertension are summarized and connected with clinical studies that address the role of C-reactive protein in hypertensive disease...
Obstructive sleep apnea syndromeMassimo R Mannarino
Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Eur J Intern Med 23:586-93. 2012..A better understanding of mechanisms underlying the disease could improve therapeutic strategies and reduce the social impact of OSA syndrome...
A silent mutation of Niemann-Pick C1-like 1 and apolipoprotein E4 modulate cholesterol absorption in primary hyperlipidemiasGraziana Lupattelli
Department of Clinical and Experimental Medicine, Internal Medicine, Angiology and Atherosclerosis, Santa Maria della Misericordia Hospital, Piazzale Menghini, Sant Andrea delle Fratte, University of Perugia, Perugia, 06132, Italy Electronic address
J Clin Lipidol 7:147-52. 2013..816C > G (L272) of Niemann-Pick C1-like 1 (NPC1L1) and of apolipoprotein (APO) E alleles on cholesterol absorption markers, sitosterol and campesterol, in 87 patients with primary hyperlipidemias...
Diffuse muscoskeletal pain and proximal myopathy: do not forget hypovitaminosis DGianluigi Fabbriciani
Department of Clinical and Experimental Medicine, Institute of Internal Medicine, Angiology and Arteriosclerosis Diseases, University of Perugia, Perugia, Italy
J Clin Rheumatol 16:34-7. 2010..The patient was started on a treatment with 20,000 IU of vitamin D3 once a week plus 1 g/d of calcium. Eight months later, gait disturbances have significantly improved and laboratory findings have all normalized...
The influence of iloprost on blood rheology and tissue perfusion in patients with intermittent claudicationGiovanni Ciuffetti
Angiology Section, Department of Clinical and Experimental Medicine, Perugia General Hospital, Italy
Kardiol Pol 59:197-204. 2003..CONCLUSIONS: Our results show that the infusion of a single dose of Iloprost in patients with PVD is associated with a significant improvement in microvascular functioning..
Postprandial lipemia and associated metabolic disturbances in healthy and hyperlipemic postmenopausal womenM Pirro
Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Metabolism 50:330-4. 2001..The presence of the features of insulin resistance syndrome could contribute to the deterioration of postprandial lipemic response in these subjects...
Endothelial injury and repair: a novel theory for atherosclerosisElmo Mannarino
Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Angiology 59:69S-72S. 2008....
Renal dysfunction predicts long-term mortality in patients with lower extremity arterial diseaseL Pasqualini
Department of Clinical and Experimental Medicine, Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
J Intern Med 262:668-77. 2007..Patients with renal insufficiency tend to suffer from advanced atherosclerosis and exhibit a reduced life expectancy...
Postprandial endothelial impairment and reduced glutathione levels in postmenopausal womenD Siepi
Internal Medicine, Angiology and Atherosclerosis, University of Perugia, Via Brunacci Brunamonti 2, I 06122 Perugia, Italy
Ann Nutr Metab 46:32-7. 2002..The aim of the study was to clarify the vascular effects of postprandial state in postmenopausal women...
Low-density lipoprotein size in primary hypothyroidism. Effects of hormone replacement therapyA R Roscini
Internal Medicine Angiology and Atherosclerosis Unit, University of Perugia, Italy
Ann Nutr Metab 43:374-9. 1999....
Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activityG Vaudo
Internal Medicine, Angiology and Arteriosclerosis, University of Perugia School of Medicine, Perugia, Italy
Ann Rheum Dis 63:31-5. 2004..Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease. Endothelial dysfunction represents the earliest stage of atherosclerosis...
Endothelial progenitor cells are mobilized after major laparotomic surgery in patients with cancerG Schillaci
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Int J Immunopathol Pharmacol 22:1035-41. 2009..The potential adverse effects of surgical stress-induced EPC mobilization on tumor and metastasis growth in cancer patients need to be addressed in future studies...
Prognostic impact of low-shear whole blood viscosity in hypertensive menG Ciuffetti
Unit of Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, 06156 Perugia, Italy
Eur J Clin Invest 35:93-8. 2005..The aim of this study was to assess whether whole blood viscosity (WBV) could be useful in assessing cardiovascular risk in men with a first diagnosis of hypertension...
Impaired flow-mediated vasoactivity during post-prandial phase in young healthy menS Marchesi
Sezione di Medicina Interna, Angiologia e Malattie da Arteriosclerosi, University of Perugia, Policlinico Monteluce, Italy
Atherosclerosis 153:397-402. 2000..These data provide support for a role of post-prandial phase in vascular regulation in young healthy subjects...
Effects of a phytosterol-enriched dairy product on lipids, sterols and 8-isoprostane in hypercholesterolemic patients: a multicenter Italian studyE Mannarino
Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita di Perugia, Perugia, Italy
Nutr Metab Cardiovasc Dis 19:84-90. 2009....
Pasta naturally enriched with isoflavone aglycons from soy germ reduces serum lipids and improves markers of cardiovascular riskCarlo Clerici
Clinica di Gastroenterologia ed Epatologia, Universita degli Studi di Perugia, Perugia, Italy 06100
J Nutr 137:2270-8. 2007..In conclusion, pasta naturally enriched with isoflavone aglycons and lacking soy protein had a significant hypocholesterolemic effect beyond a Step II diet and improved other cardiovascular risk markers...
Effects of fenofibrate on endothelial function and cell adhesion molecules during post-prandial lipemia in hypertriglyceridemiaS Marchesi
Unit of Internal Medicine, Angiology and Atherosclerosis, University of Perugia, Perugia, Italy
J Clin Pharm Ther 28:419-24. 2003..Fasting and post-prandial hypertriglyceridemia have been associated with endothelial dysfunction...
Diagnostic performance of a multiple real-time PCR assay in patients with suspected sepsis hospitalized in an internal medicine wardLeonella Pasqualini
Internal Medicine, Angiology and Arteriosclerosis Diseases Section, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Clin Microbiol 50:1285-8. 2012..049) compared to BC. These results suggest that, in patients with suspected sepsis, hospitalized in an internal medicine ward, SF could be a highly valuable adjunct to conventional BC, particularly in patients under antibiotic treatment...
Clopidogrel: hemorheological effects in subjects with subclinical atherosclerosisG Ciuffetti
Internal Medicine, Angiology and Arteriosclerosis Diseases Department, University of Perugia, Italy
Clin Hemorheol Microcirc 25:31-9. 2001....
Blood rheology in men with essential hypertension and capillary rarefactionG Ciuffetti
Department of Clinical and Experimental Medicine, Section of Internal Medicine, Angiology and Atherosclerosis Disease, University of Perugia Monteluce Hospital, Perugia, Italy
J Hum Hypertens 16:533-7. 2002..05). The conclusions were that in untreated hypertensive men, capillary rarefaction and hyperviscosity are associated to an increased diastolic blood pressure and to an adverse haemorheological profile...
A human model of platelet-leucocyte adhesive interactions during controlled ischaemia in patients with peripheral vascular diseaseL Pasqualini
Internal Medicine, Angiology and Arteriosclerosis Disease Clinic, Department of Clinical and Experimental Medicine, University of Perugia, 06122 Perugia, Italy
J Clin Pathol 55:946-50. 2002..CONCLUSIONS: Clopidogrel, by inhibiting platelet activation and aggregation, might also block the vicious cycle of leucocyte-platelet activation, thus improving the functioning of the microcirculation...
Molecular biology of atherosclerosisElmo Mannarino
Unit of Internal Medicine, Angiology and Atherosclerosis Diseases, Department of Clinical and Experimental Medicine University of Perugia, Perugia, Italy
Clin Cases Miner Bone Metab 5:57-62. 2008....
Left ventricular hypertrophy reversal and prevention of diabetes: two birds with one stone?Giuseppe Schillaci
Hypertension 50:851-3. 2007
Inflammatory markers and long-term risk of ischemic heart disease in men A 13-year follow-up of the Quebec Cardiovascular StudyAnnie C St-Pierre
Department of Nutrition, Institute on Nutraceuticals and Functional Foods, Laval University, 2440 Hochelaga Blvd, Ste-Foy, Qu, Canada G1K 7P4
Atherosclerosis 182:315-21. 2005..An inflammation score based on high plasma IL-6 and fibrinogen levels used in combination with traditional risk factors may improve our ability to adequately identify high risk individuals...
Plasma free fatty acid levels and the risk of ischemic heart disease in men: prospective results from the Québec Cardiovascular StudyMatteo Pirro
Department of Food Science and Nutrition, Lipid Research Center, R-9600 CHUL Research Center, 2705 Laurier Boulevard, Ste-Foy, G1V 4G2, Quebec, Canada
Atherosclerosis 160:377-84. 2002..However, a single fasting measurement of plasma FFA levels does not appear to improve our ability to predict IHD onset in men when information on other risk factors is considered...
Effect of plasma C-reactive protein levels in modulating the risk of coronary heart disease associated with small, dense, low-density lipoproteins in men (The Quebec Cardiovascular Study)Annie C St-Pierre
Institute on Nutraceuticals and Fonctionnal Foods, Laval University, Ste-Foy, , Canada
Am J Cardiol 91:555-8. 2003..6 vs 3.0). Thus, increased plasma CRP levels further elevate the risk of CHD associated with having small, dense LDL particles...
Serum triglyceride concentration and coronary heart diseaseGiuseppe Schillaci
Circulation 105:e54. 2002
Hypoadiponectinemia: a novel link between obesity and hypertension?Giuseppe Schillaci
Hypertension 49:1217-9. 2007
Long-term weight loss and blood pressure reduction: the perfect is the enemy of the goodGiuseppe Schillaci
Am J Hypertens 19:1101-2. 2006
Effects of atorvastatin on electrophoretic characteristics of LDL particles among subjects with heterozygous familial hypercholesterolemiaMathieu Larivière
Lipid Research Center, CHUL Research Center, Laval University, Room S 102 2705, Laurier Blvd, Laval, Quebec, Canada G1V 4G2
Atherosclerosis 167:97-104. 2003..These results also suggest that genetic and metabolic factors may be important determinants of atorvastatin-induced changes of LDL particle size and distribution among FH heterozygotes...
Treating hypertensive non-dippers: additional benefit from nocturnal blood pressure reduction?Giuseppe Schillaci
Cardiovasc Drugs Ther 19:169-71. 2005
