Matteo Pirro

Summary

Affiliation: University of Perugia
Country: Italy

Publications

  1. doi request reprint Association between circulating osteoprogenitor cell numbers and bone mineral density in postmenopausal osteoporosis
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1 06129 Perugia, Italy
    Osteoporos Int 21:297-306. 2010
  2. doi request reprint On-treatment C-reactive protein and HDL cholesterol levels in patients at intermediate cardiovascular risk: Impact on carotid intima-media thickness
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy Electronic address
    Life Sci 93:338-43. 2013
  3. doi request reprint Association between circulating osteoblast progenitor cells and aortic calcifications in women with postmenopausal osteoporosis
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, 06129 Perugia, Italy Electronic address
    Nutr Metab Cardiovasc Dis 23:466-72. 2013
  4. ncbi request reprint Association of parathyroid hormone and 25-OH-vitamin D levels with arterial stiffness in postmenopausal women with vitamin D insufficiency
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Atheroscler Thromb 19:924-31. 2012
  5. doi request reprint Association between thyroid hormone levels, the number of circulating osteoprogenitor cells, and bone mineral density in euthyroid postmenopausal women
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Metabolism 61:569-76. 2012
  6. doi request reprint Influence of short-term rosuvastatin therapy on endothelial progenitor cells and endothelial function
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Cardiovasc Pharmacol Ther 14:14-21. 2009
  7. ncbi request reprint Reduced number of circulating endothelial progenitors and HOXA9 expression in CD34+ cells of hypertensive patients
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Hypertens 25:2093-9. 2007
  8. ncbi request reprint Attenuation of inflammation with short-term dietary intervention is associated with a reduction of arterial stiffness in subjects with hypercholesterolaemia
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Eur J Cardiovasc Prev Rehabil 11:497-502. 2004
  9. ncbi request reprint Low-grade systemic inflammation impairs arterial stiffness in newly diagnosed hypercholesterolaemia
    M Pirro
    University of Perugia, Perugia, Italy
    Eur J Clin Invest 34:335-41. 2004
  10. doi request reprint Circulating immature osteoprogenitor cells and arterial stiffening in postmenopausal osteoporosis
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini 1, Perugia, Italy
    Nutr Metab Cardiovasc Dis 21:636-42. 2011

Collaborators

Detail Information

Publications87

  1. doi request reprint Association between circulating osteoprogenitor cell numbers and bone mineral density in postmenopausal osteoporosis
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1 06129 Perugia, Italy
    Osteoporos Int 21:297-306. 2010
    ..Conversely, the increased number of alkaline phosphatase/CD34-positive cells may reflect the reactive bone marrow contribution to bone formation...
  2. doi request reprint On-treatment C-reactive protein and HDL cholesterol levels in patients at intermediate cardiovascular risk: Impact on carotid intima-media thickness
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy Electronic address
    Life Sci 93:338-43. 2013
    ..The influence of blood pressure and anti-hypertensive therapy on the association between CRP and CIMT was evaluated...
  3. doi request reprint Association between circulating osteoblast progenitor cells and aortic calcifications in women with postmenopausal osteoporosis
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, 06129 Perugia, Italy Electronic address
    Nutr Metab Cardiovasc Dis 23:466-72. 2013
    ..We investigated the relationship between OPCs and aortic calcifications in women with postmenopausal osteoporosis...
  4. ncbi request reprint Association of parathyroid hormone and 25-OH-vitamin D levels with arterial stiffness in postmenopausal women with vitamin D insufficiency
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Atheroscler Thromb 19:924-31. 2012
    ..We therefore investigated the association between PTH and aortic stiffness in postmenopausal women with reduced 25-OH-vitamin D levels...
  5. doi request reprint Association between thyroid hormone levels, the number of circulating osteoprogenitor cells, and bone mineral density in euthyroid postmenopausal women
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Metabolism 61:569-76. 2012
    ..Exposure of CD34+ cells to physiological triiodothyronine concentrations stimulates mineralization in vitro...
  6. doi request reprint Influence of short-term rosuvastatin therapy on endothelial progenitor cells and endothelial function
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Cardiovasc Pharmacol Ther 14:14-21. 2009
    ....
  7. ncbi request reprint Reduced number of circulating endothelial progenitors and HOXA9 expression in CD34+ cells of hypertensive patients
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Hypertens 25:2093-9. 2007
    ..The objective of our study was to measure the expression of HOXA9 in CD34+ cells from hypertensive patients and to investigate its correlation with the number of circulating EPCs...
  8. ncbi request reprint Attenuation of inflammation with short-term dietary intervention is associated with a reduction of arterial stiffness in subjects with hypercholesterolaemia
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Eur J Cardiovasc Prev Rehabil 11:497-502. 2004
    ..Whether mitigation of low-grade systemic inflammation, through a low-cholesterol/low-saturated fat diet, may have a role in improving arterial stiffness is still untested...
  9. ncbi request reprint Low-grade systemic inflammation impairs arterial stiffness in newly diagnosed hypercholesterolaemia
    M Pirro
    University of Perugia, Perugia, Italy
    Eur J Clin Invest 34:335-41. 2004
    ....
  10. doi request reprint Circulating immature osteoprogenitor cells and arterial stiffening in postmenopausal osteoporosis
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini 1, Perugia, Italy
    Nutr Metab Cardiovasc Dis 21:636-42. 2011
    ..We investigated whether an increased number of circulating OPCs underlies the association of osteoporosis with arterial stiffness...
  11. doi request reprint High weight or body mass index increase the risk of vertebral fractures in postmenopausal osteoporotic women
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Hospital Santa Maria della Misericordia, Piazzale Menghini 1, 06129 Perugia, Italy
    J Bone Miner Metab 28:88-93. 2010
    ..In conclusion, among postmenopausal women with osteoporosis, body weight and BMI are associated with a higher likelihood of having a vertebral fracture, irrespective of the positive association between weight and BMD...
  12. doi request reprint Hypercholesterolemia-associated endothelial progenitor cell dysfunction
    Matteo Pirro
    Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita degli Studi di Perugia, Ospedale S Maria della Misericordia, Perugia, Italy
    Ther Adv Cardiovasc Dis 2:329-39. 2008
    ....
  13. doi request reprint Cardiovascular risk factors and recommended lipid goals attainment among patients referred in a tertiary care lipid clinic
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, and Hospital Santa Maria della Misericordia, Piazzale Menghini, Perugia, Italy
    Eur J Intern Med 22:412-7. 2011
    ..We investigated the burden of cardiovascular risk and the distance of lipid fractions from the recommended targets by statin therapy and risk status in patients referred to a tertiary care lipid clinic...
  14. ncbi request reprint Microparticles derived from endothelial progenitor cells in patients at different cardiovascular risk
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Atherosclerosis 197:757-67. 2008
    ..We also investigated the relationship of EPCs-derived microparticles to cardiovascular risk factors and aortic stiffness, a marker of cardiovascular risk and impaired vascular repair by EPCs...
  15. ncbi request reprint Increased ratio of CD31+/CD42- microparticles to endothelial progenitors as a novel marker of atherosclerosis in hypercholesterolemia
    Matteo Pirro
    Department of Clinical and Experimental Medicine, University of Perugia, Italy
    Arterioscler Thromb Vasc Biol 26:2530-5. 2006
    ..We also studied the in vitro effect of microparticles from hypercholesterolemic patients on endothelial progenitor survival...
  16. doi request reprint Preclinical vascular damage in white postmenopausal women: the relevance of osteoprotegerin
    Donatella Siepi
    Unit of Internal Medicine, Angiology and Atherosclerosis, Ospedale S Maria della Misericordia University of Perugia, Piazzale Menghini, 1 06129 Perugia, Italy
    Metabolism 57:321-5. 2008
    ..On this basis, we could speculate that OPG levels may be considered not a cardiovascular risk condition but a defense against atherosclerotic progression...
  17. ncbi request reprint Effects of rosuvastatin on 3-nitrotyrosine and aortic stiffness in hypercholesterolemia
    Matteo Pirro
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale R Silvestrini, S Andrea delle Fratte, 06100 Perugia, Italy
    Nutr Metab Cardiovasc Dis 17:436-41. 2007
    ..The aim of the present study was to investigate the short-term effect of cholesterol lowering with rosuvastatin on 3-nitrotyrosine (3-NT), a marker of peroxynitrite-mediated oxidative stress, and on arterial stiffness...
  18. ncbi request reprint Early vascular damage in primary hypoalphalipoproteinemia
    Gaetano Vaudo
    Department of Internal Medicine, Angiology, and Atherosclerosis, University of Perugia, Perugia, Italy
    Metabolism 52:328-32. 2003
    ..45 and -0.49, respectively; both P <.05). In conclusion, subjects with primary hypoalpha, without overt cardiovascular disease, are characterized by an impaired endothelial function and by an increase in large-artery IMT...
  19. ncbi request reprint Ambulatory arterial stiffness index is not a specific marker of reduced arterial compliance
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Hypertension 49:986-91. 2007
    ....
  20. ncbi request reprint Simvastatin increases bone mineral density in hypercholesterolemic postmenopausal women
    Graziana Lupattelli
    Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of, Perugia, Italy
    Metabolism 53:744-8. 2004
    ..860 +/- 0.110 v 0.853 +/- 0.096 and 0.847 +/- 0.095; P <.05). In conclusion, as partly suggested by retrospective or observational data, this longitudinal study indicates that simvastatin treatment exerts a beneficial effect on BMD...
  21. ncbi request reprint Metabolic syndrome is associated with aortic stiffness in untreated essential hypertension
    Giuseppe Schillaci
    University of Perugia, Perugia, Italy
    Hypertension 45:1078-82. 2005
    ..Central, but not general, adiposity is an important determinant of aortic stiffness in hypertension...
  22. ncbi request reprint Relevance of homocysteine on brachial flow-mediated vasodilatation and carotid and femoral intima-media thickness in patients with hypercholesterolemia
    Gaetano Vaudo
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia School of Medicine, Via Brunamonti 51, 06122 Perugia, Italy
    Am J Cardiol 93:1413-6, A9. 2004
    ..Homocysteine levels seem to be an additional factor in the initial atherosclerotic damage of patients with hypercholesterolemia...
  23. ncbi request reprint Increased C-reactive protein concentrations in never-treated hypertension: the role of systolic and pulse pressures
    Giuseppe Schillaci
    Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Policlinico Monteluce, Universita degli Studi di Perugia, Via B Brunamonti 51, 06122 Perugia, Italy
    J Hypertens 21:1841-6. 2003
    ....
  24. ncbi request reprint Age-specific relationship of aortic pulse wave velocity with left ventricular geometry and function in hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, IT 06129 Perugia, Italy
    Hypertension 49:317-21. 2007
    ..With increasing age, a relationship between aortic PWV (as a measure of arterial stiffness) and left ventricular concentric geometry emerges, which ultimately leads to a depressed ventricular systolic function...
  25. ncbi request reprint Human endothelial impairment in sepsis
    Gaetano Vaudo
    Internal Medicine, Angiology and Atherosclerosis University of Perugia, S Maria della Misericordia Hospital Piazzale Menghini, 1, 06129 Perugia, Italy
    Atherosclerosis 197:747-52. 2008
    ....
  26. ncbi request reprint Direct association between high-density lipoprotein cholesterol and endothelial function in hyperlipemia
    Graziana Lupattelli
    Unit of Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Am J Cardiol 90:648-50. 2002
  27. ncbi request reprint Relation between renal function within the normal range and central and peripheral arterial stiffness in hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Hypertension 48:616-21. 2006
    ..These relations are in part independent from the effect of several confounders, including age, sex, and blood pressure values...
  28. ncbi request reprint Different impact of the metabolic syndrome on left ventricular structure and function in hypertensive men and women
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Hypertension 47:881-6. 2006
    ..The effect of MS is more pronounced in women and is partly independent from the effect of several hemodynamic and nonhemodynamic determinants of LV mass...
  29. ncbi request reprint Mechanisms of high-density lipoprotein cholesterol effects on the endothelial function in hyperlipemia
    Graziana Lupattelli
    Department of Clinical and Experimental Medicine, University of Perugia, Italy
    Metabolism 52:1191-5. 2003
    ..05). Our data suggest that in hyperlipemic subjects free of cardiovascular disease low HDL-c negatively modulates endothelial function through a lack of oxidation inhibition and a concomitant overexpression of adhesion molecules...
  30. doi request reprint Aortic stiffness in untreated adult patients with human immunodeficiency virus infection
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Hypertension 52:308-13. 2008
    ..PWV increases with increasing serum gamma-glutamyl transpeptidase concentration. Our data support the hypothesis that HIV infection is a risk factor for arteriosclerosis...
  31. ncbi request reprint Plasma C-reactive protein in subjects with hypo/hyperalphalipoproteinemias
    Matteo Pirro
    Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Italy
    Metabolism 52:432-6. 2003
    ..In conclusion, in subjects with Hypo-A or Hyper-A, HDL-C levels may account for plasma CRP variations independent of other potential cardiovascular risk factors...
  32. ncbi request reprint Paraoxonase-1 activity modulates endothelial function in patients with peripheral arterial disease
    Leonella Pasqualini
    Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Atherosclerosis 183:349-54. 2005
    ..40, p=0.008), brachial-artery diameter (beta=-0.39, p=0.01) and male sex (beta=-0.27, p=0.04). These finding support the importance of PON1 activity as a modulating factor of the endothelial function...
  33. doi request reprint Large-artery stiffness: a reversible marker of cardiovascular risk in primary hyperparathyroidism
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Atherosclerosis 218:96-101. 2011
    ..We investigated whether aortic stiffness, an early marker of arteriosclerosis and a strong predictor of cardiovascular risk, is increased in pHPT, and whether it improves after parathyroidectomy...
  34. ncbi request reprint Prognostic value of elevated white blood cell count in hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Perugia, Italy
    Am J Hypertens 20:364-9. 2007
    ..However, as yet the prognostic significance of white blood cell (WBC) count in the setting of uncomplicated hypertension has not been investigated...
  35. doi request reprint A silent mutation of Niemann-Pick C1-like 1 and apolipoprotein E4 modulate cholesterol absorption in primary hyperlipidemias
    Graziana Lupattelli
    Department of Clinical and Experimental Medicine, Internal Medicine, Angiology and Atherosclerosis, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy
    J Clin Lipidol 7:147-52. 2013
    ..816C > G (L272) of Niemann-Pick C1-like 1 (NPC1L1) and of apolipoprotein (APO) E alleles on cholesterol absorption markers, sitosterol and campesterol, in 87 patients with primary hyperlipidemias...
  36. doi request reprint Cholesterol metabolism differs after statin therapy according to the type of hyperlipemia
    Graziana Lupattelli
    Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Italy
    Life Sci 90:846-50. 2012
    ..Common hyperlipemias have shown different patterns of cholesterol metabolism. We evaluated whether cholesterol absorption and synthesis may differ after statin therapy in primary hyperlipemias...
  37. ncbi request reprint Plasma viscosity in isolated systolic hypertension: the role of pulse pressure
    Giovanni Ciuffetti
    Unit of Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Am J Hypertens 18:1005-8. 2005
    ..Systolic BP and PP appear to be major determinants of PV levels in these patients, independent of the potential proinflammatory action of traditional cardiovascular risk factors...
  38. ncbi request reprint Effect of body weight changes on 24-hour blood pressure and left ventricular mass in hypertension: a 4-year follow-up
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Via Brunamonti 51, 06122 Perugia, Italy
    Am J Hypertens 16:634-9. 2003
    ..Few data are available on the long-term effects of weight loss on 24-h blood pressure (BP) and left ventricular mass in overweight hypertensive patients...
  39. ncbi request reprint Metabolic syndrome and preclinical atherosclerosis: focus on femoral arteries
    Gaetano Vaudo
    Internal Medicine, Angiology and Atherosclerosis, University of Perugia School of Medicine, S Maria della Misericordia Hospital, Piazzale Menghini, 1, 06100, Italy
    Metabolism 56:541-6. 2007
    ..Moreover, it focused on the strong influence of metabolic syndrome on preclinical atherosclerotic lesions at the femoral site...
  40. ncbi request reprint Prognostic significance of isolated, non-specific left ventricular repolarization abnormalities in hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    J Hypertens 22:407-14. 2004
    ..The aim of this study was to investigate the prognostic significance of such changes...
  41. ncbi request reprint Anti-tumor necrosis factor-alpha response in rheumatoid arthritis is associated with an increase in serum soluble CD30
    Roberto Gerli
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Rheumatol 35:14-9. 2008
    ..To verify the contribution of this T cell subset to disease remission, sCD30 levels were analyzed longitudinally in patients with active RA following infliximab therapy...
  42. doi request reprint Prognostic value of low and high ankle-brachial index in hospitalized medical patients
    Leonella Pasqualini
    Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Eur J Intern Med 23:240-4. 2012
    ..The ankle-brachial pressure index (ABI) represents a noninvasive, objective tool to diagnose PAD and to predict adverse outcome...
  43. ncbi request reprint Prostaglandin E1 improves endothelial function in critical limb ischemia
    Simona Marchesi
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Via Brunacci Brunamonti, 51 IT 06122 Perugia, Italy
    J Cardiovasc Pharmacol 41:249-53. 2003
    ..0 +/- 1.1% to 3.1 +/- 0.6% and 5.2 +/- 2.1%, both p < 0.05). In conclusion, treatment with PGE1 determines a significant improvement in endothelial function in patients with critical limb ischemia...
  44. ncbi request reprint Prognostic impact of prolonged ventricular repolarization in hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, 06132 Perugia, Italy
    Arch Intern Med 166:909-13. 2006
    ..QT interval prolongation on the surface electrocardiogram (ECG) predicts cardiovascular complications in high-risk subjects, but its prognostic role in uncomplicated hypertension has been understudied...
  45. doi request reprint Osteoanabolic therapy: a non-surgical option of treatment for Kümmell's disease?
    Gianluigi Fabbriciani
    Institute of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Piazzale Menghini, 1, 06129 Perugia, Italy
    Rheumatol Int 32:1371-4. 2012
    ..Moreover in this condition, osteoanabolic treatment may be used in patients with Kümmell's disease to enhance vertebral fracture's healing and contribute to back pain relief...
  46. doi request reprint Aortic stiffness is increased in polymyalgia rheumatica and improves after steroid treatment
    Giuseppe Schillaci
    Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita degli Studi di Perugia, Ospedale S Maria della Misericordia piazzale G Menghini, 1 06129 Perugia, Italy
    Ann Rheum Dis 71:1151-6. 2012
    ..A study was undertaken to investigate whether aortic stiffness is increased in PMR and whether it improves after steroid treatment...
  47. ncbi request reprint Increased postprandial lipemia in patients with normolipemic peripheral arterial disease
    Graziana Lupattelli
    Internal Medicine, Angiology, and Atherosclerosis Unit, Department of Clinical and Experimental Medicine, University of Perugia, Italy
    Am Heart J 143:733-8. 2002
    ....
  48. doi request reprint Adiponectin and hypertension: the connection lies within the fat
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis Disease, University of Perugia, Hospital S Maria della Misericordia, Perugia, Italy
    Am J Hypertens 21:374-5. 2008
  49. ncbi request reprint Prognostic value of treatment-induced changes in twenty-four-hour mean and pulse pressures in adult hypertensive patients
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Am J Cardiol 90:896-9. 2002
  50. doi request reprint Combined effects of office and 24-h blood pressure on aortic stiffness in human hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia Medical School, Hospital Santa Maria della Misericordia, Piazzale Menghini, 1, IT 06129 Perugia, Italy
    J Hypertens 29:869-75. 2011
    ..Office BP may not always reflect BP behaviour away from the medical environment, and it is uncertain whether office or out-of-office BP values are stronger determinants of arterial stiffness...
  51. ncbi request reprint Prognostic value of the metabolic syndrome in essential hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    J Am Coll Cardiol 43:1817-22. 2004
    ..We sought to determine the prognostic significance of the metabolic syndrome in hypertension...
  52. doi request reprint Diffuse muscoskeletal pain and proximal myopathy: do not forget hypovitaminosis D
    Gianluigi Fabbriciani
    Department of Clinical and Experimental Medicine, Institute of Internal Medicine, Angiology and Arteriosclerosis Diseases, University of Perugia, Perugia, Italy
    J Clin Rheumatol 16:34-7. 2010
    ..The patient was started on a treatment with 20,000 IU of vitamin D3 once a week plus 1 g/d of calcium. Eight months later, gait disturbances have significantly improved and laboratory findings have all normalized...
  53. doi request reprint Transient osteoporosis of the hip: successful treatment with teriparatide
    Gianluigi Fabbriciani
    Institute of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Rheumatol Int 32:1367-70. 2012
    ..Disappearance of the symptoms and normalization of MRI were obtained...
  54. doi request reprint Visceral fat positively correlates with cholesterol synthesis in dyslipidaemic patients
    Graziana Lupattelli
    Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Italy
    Eur J Clin Invest 42:164-70. 2012
    ....
  55. ncbi request reprint CD4+CD28- T lymphocytes contribute to early atherosclerotic damage in rheumatoid arthritis patients
    Roberto Gerli
    Center for the Study of Rheumatic Diseases, Section of Internal Medicine and Oncological Sciences, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico di Monteluce, I 06122 Perugia, Italy
    Circulation 109:2744-8. 2004
    ..However, the potential association between CD4+CD28null T cells and early atherosclerotic changes in RA has never been investigated...
  56. ncbi request reprint Endothelial microparticles and arterial stiffness: casual coincidence or causative culprit?
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Am J Hypertens 20:965-6. 2007
  57. ncbi request reprint Impact of treatment with protease inhibitors on aortic stiffness in adult patients with human immunodeficiency virus infection
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology, and Arteriosclerosis, University of Perugia, Italy
    Arterioscler Thromb Vasc Biol 25:2381-5. 2005
    ..We hypothesized that aortic stiffness, an early marker of arteriosclerosis, may be increased in HIV patients treated with protease inhibitors...
  58. ncbi request reprint C-reactive protein in hypertension: clinical significance and predictive value
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis Disease, University of Perugia Medical School, Hospital S Maria della Misericordia, Piazzale Menghini, 1, IT 06132 Perugia, Italy
    Nutr Metab Cardiovasc Dis 16:500-8. 2006
    ..In this review, various aspects of the pathogenesis of inflammation in hypertension are summarized and connected with clinical studies that address the role of C-reactive protein in hypertensive disease...
  59. doi request reprint Obstructive sleep apnea syndrome
    Massimo R Mannarino
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Eur J Intern Med 23:586-93. 2012
    ..A better understanding of mechanisms underlying the disease could improve therapeutic strategies and reduce the social impact of OSA syndrome...
  60. ncbi request reprint The influence of iloprost on blood rheology and tissue perfusion in patients with intermittent claudication
    Giovanni Ciuffetti
    Angiology Section, Department of Clinical and Experimental Medicine, Perugia General Hospital, Italy
    Kardiol Pol 59:197-204. 2003
    ..Indeed, during acute leg ischaemia factors influencing microvascular BV include the plasma fibrinogen concentration, red and white blood cell rheology, as well as platelet aggregation and activation...
  61. ncbi request reprint Postprandial lipemia and associated metabolic disturbances in healthy and hyperlipemic postmenopausal women
    M Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Metabolism 50:330-4. 2001
    ..The presence of the features of insulin resistance syndrome could contribute to the deterioration of postprandial lipemic response in these subjects...
  62. doi request reprint Baseline and post-surgery endothelial progenitor cell levels in patients with early-stage non-small-cell lung carcinoma: impact on cancer recurrence and survival
    Matteo Pirro
    Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, University of Perugia, Perugia, Italy
    Eur J Cardiothorac Surg 44:e245-52. 2013
    ..The prospective influence of baseline and post-surgery EPC levels on cancer recurrence and survival was investigated...
  63. doi request reprint Endothelial injury and repair: a novel theory for atherosclerosis
    Elmo Mannarino
    Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Angiology 59:69S-72S. 2008
    ....
  64. ncbi request reprint Renal dysfunction predicts long-term mortality in patients with lower extremity arterial disease
    L Pasqualini
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    J Intern Med 262:668-77. 2007
    ..Patients with renal insufficiency tend to suffer from advanced atherosclerosis and exhibit a reduced life expectancy...
  65. ncbi request reprint Postprandial endothelial impairment and reduced glutathione levels in postmenopausal women
    D Siepi
    Internal Medicine, Angiology and Atherosclerosis, University of Perugia, Via Brunacci Brunamonti 2, I 06122 Perugia, Italy
    Ann Nutr Metab 46:32-7. 2002
    ..The aim of the study was to clarify the vascular effects of postprandial state in postmenopausal women...
  66. ncbi request reprint Low-density lipoprotein size in primary hypothyroidism. Effects of hormone replacement therapy
    A R Roscini
    Internal Medicine Angiology and Atherosclerosis Unit, University of Perugia, Italy
    Ann Nutr Metab 43:374-9. 1999
    ....
  67. ncbi request reprint Impaired flow-mediated vasoactivity during post-prandial phase in young healthy men
    S Marchesi
    Sezione di Medicina Interna, Angiologia e Malattie da Arteriosclerosi, University of Perugia, Policlinico Monteluce, Italy
    Atherosclerosis 153:397-402. 2000
    ..These data provide support for a role of post-prandial phase in vascular regulation in young healthy subjects...
  68. ncbi request reprint Endothelial progenitor cells are mobilized after major laparotomic surgery in patients with cancer
    G Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Int J Immunopathol Pharmacol 22:1035-41. 2009
    ..The potential adverse effects of surgical stress-induced EPC mobilization on tumor and metastasis growth in cancer patients need to be addressed in future studies...
  69. pmc Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity
    G Vaudo
    Internal Medicine, Angiology and Arteriosclerosis, University of Perugia School of Medicine, Perugia, Italy
    Ann Rheum Dis 63:31-5. 2004
    ..Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease. Endothelial dysfunction represents the earliest stage of atherosclerosis...
  70. ncbi request reprint Prognostic impact of low-shear whole blood viscosity in hypertensive men
    G Ciuffetti
    Unit of Internal Medicine, Angiology and Atherosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, 06156 Perugia, Italy
    Eur J Clin Invest 35:93-8. 2005
    ..The aim of this study was to assess whether whole blood viscosity (WBV) could be useful in assessing cardiovascular risk in men with a first diagnosis of hypertension...
  71. doi request reprint Effects of a phytosterol-enriched dairy product on lipids, sterols and 8-isoprostane in hypercholesterolemic patients: a multicenter Italian study
    E Mannarino
    Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Universita di Perugia, Perugia, Italy
    Nutr Metab Cardiovasc Dis 19:84-90. 2009
    ....
  72. ncbi request reprint Pasta naturally enriched with isoflavone aglycons from soy germ reduces serum lipids and improves markers of cardiovascular risk
    Carlo Clerici
    Clinica di Gastroenterologia ed Epatologia, Universita degli Studi di Perugia, Perugia, Italy 06100
    J Nutr 137:2270-8. 2007
    ..In conclusion, pasta naturally enriched with isoflavone aglycons and lacking soy protein had a significant hypocholesterolemic effect beyond a Step II diet and improved other cardiovascular risk markers...
  73. ncbi request reprint Effects of fenofibrate on endothelial function and cell adhesion molecules during post-prandial lipemia in hypertriglyceridemia
    S Marchesi
    Unit of Internal Medicine, Angiology and Atherosclerosis, University of Perugia, Perugia, Italy
    J Clin Pharm Ther 28:419-24. 2003
    ..Fasting and post-prandial hypertriglyceridemia have been associated with endothelial dysfunction...
  74. pmc Diagnostic performance of a multiple real-time PCR assay in patients with suspected sepsis hospitalized in an internal medicine ward
    Leonella Pasqualini
    Internal Medicine, Angiology and Arteriosclerosis Diseases Section, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Clin Microbiol 50:1285-8. 2012
    ..049) compared to BC. These results suggest that, in patients with suspected sepsis, hospitalized in an internal medicine ward, SF could be a highly valuable adjunct to conventional BC, particularly in patients under antibiotic treatment...
  75. pmc A human model of platelet-leucocyte adhesive interactions during controlled ischaemia in patients with peripheral vascular disease
    L Pasqualini
    Internal Medicine, Angiology and Arteriosclerosis Disease Clinic, Department of Clinical and Experimental Medicine, University of Perugia, 06122 Perugia, Italy
    J Clin Pathol 55:946-50. 2002
    ....
  76. ncbi request reprint Clopidogrel: hemorheological effects in subjects with subclinical atherosclerosis
    G Ciuffetti
    Internal Medicine, Angiology and Arteriosclerosis Diseases Department, University of Perugia, Italy
    Clin Hemorheol Microcirc 25:31-9. 2001
    ....
  77. ncbi request reprint Blood rheology in men with essential hypertension and capillary rarefaction
    G Ciuffetti
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Angiology and Atherosclerosis Disease, University of Perugia Monteluce Hospital, Perugia, Italy
    J Hum Hypertens 16:533-7. 2002
    ..05). The conclusions were that in untreated hypertensive men, capillary rarefaction and hyperviscosity are associated to an increased diastolic blood pressure and to an adverse haemorheological profile...
  78. pmc Molecular biology of atherosclerosis
    Elmo Mannarino
    Unit of Internal Medicine, Angiology and Atherosclerosis Diseases, Department of Clinical and Experimental Medicine University of Perugia, Perugia, Italy
    Clin Cases Miner Bone Metab 5:57-62. 2008
    ....
  79. ncbi request reprint Effects of atorvastatin on electrophoretic characteristics of LDL particles among subjects with heterozygous familial hypercholesterolemia
    Mathieu Larivière
    Lipid Research Center, CHUL Research Center, Laval University, Room S 102 2705, Laurier Blvd, Laval, Quebec, Canada G1V 4G2
    Atherosclerosis 167:97-104. 2003
    ..These results also suggest that genetic and metabolic factors may be important determinants of atorvastatin-induced changes of LDL particle size and distribution among FH heterozygotes...
  80. ncbi request reprint Serum triglyceride concentration and coronary heart disease
    Giuseppe Schillaci
    Circulation 105:e54. 2002
  81. ncbi request reprint Left ventricular hypertrophy reversal and prevention of diabetes: two birds with one stone?
    Giuseppe Schillaci
    Hypertension 50:851-3. 2007
  82. ncbi request reprint Plasma free fatty acid levels and the risk of ischemic heart disease in men: prospective results from the Québec Cardiovascular Study
    Matteo Pirro
    Department of Food Science and Nutrition, Lipid Research Center, R 9600 CHUL Research Center, 2705 Laurier Boulevard, Ste Foy, G1V 4G2, Quebec, Canada
    Atherosclerosis 160:377-84. 2002
    ..However, a single fasting measurement of plasma FFA levels does not appear to improve our ability to predict IHD onset in men when information on other risk factors is considered...
  83. ncbi request reprint Effect of plasma C-reactive protein levels in modulating the risk of coronary heart disease associated with small, dense, low-density lipoproteins in men (The Quebec Cardiovascular Study)
    Annie C St-Pierre
    Institute on Nutraceuticals and Fonctionnal Foods, Laval University, Ste Foy, Quebec, Canada
    Am J Cardiol 91:555-8. 2003
    ..6 vs 3.0). Thus, increased plasma CRP levels further elevate the risk of CHD associated with having small, dense LDL particles...
  84. ncbi request reprint Hypoadiponectinemia: a novel link between obesity and hypertension?
    Giuseppe Schillaci
    Hypertension 49:1217-9. 2007
  85. ncbi request reprint Long-term weight loss and blood pressure reduction: the perfect is the enemy of the good
    Giuseppe Schillaci
    Am J Hypertens 19:1101-2. 2006
  86. ncbi request reprint Inflammatory markers and long-term risk of ischemic heart disease in men A 13-year follow-up of the Quebec Cardiovascular Study
    Annie C St-Pierre
    Department of Nutrition, Institute on Nutraceuticals and Functional Foods, Laval University, 2440 Hochelaga Blvd, Ste Foy, Que, Canada G1K 7P4
    Atherosclerosis 182:315-21. 2005
    ..An inflammation score based on high plasma IL-6 and fibrinogen levels used in combination with traditional risk factors may improve our ability to adequately identify high risk individuals...
  87. ncbi request reprint Treating hypertensive non-dippers: additional benefit from nocturnal blood pressure reduction?
    Giuseppe Schillaci
    Cardiovasc Drugs Ther 19:169-71. 2005