Stefano Pini

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. ncbi Awareness of illness in patients with bipolar I disorder with or without comorbid anxiety disorders
    Stefano Pini
    Department of Psychiatry, Pharmacology, Neurobiology and Bio technology, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Aust N Z J Psychiatry 37:355-61. 2003
  2. ncbi [Approach to bipolar spectrum and subthreshold mood disorders]
    Stefano Pini
    Dipartimento di Psichiatria, Neurobiologia, Universita di Pisa, Pisa, Italy
    Riv Psichiatr 46:233-41. 2011
  3. ncbi Prevalence and burden of bipolar disorders in European countries
    Stefano Pini
    Department of Psychiatry, University of Pisa, Via Roma, 67 56100, Pisa, Italy
    Eur Neuropsychopharmacol 15:425-34. 2005
  4. ncbi Clinical correlates and significance of separation anxiety in patients with bipolar disorder
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, School of Medicine, University of Pisa, Pisa, Italy
    Bipolar Disord 7:370-6. 2005
  5. ncbi Treatment of depression with comorbid anxiety disorders: differential efficacy of paroxetine versus moclobemide
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Int Clin Psychopharmacol 18:15-21. 2003
  6. ncbi Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychobiology 52:83-9. 2005
  7. ncbi The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals
    Barbara Costa
    Department of Human Morphology and Applied Biology, University of Pisa, 4 56126 Pisa, Italy
    Endocrinology 150:5438-45. 2009
  8. ncbi Reductions in platelet 18-kDa translocator protein density are associated with adult separation anxiety in patients with bipolar disorder
    Marianna Abelli
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Neuropsychobiology 62:98-103. 2010
  9. ncbi Oxytocin receptor polymorphisms and adult attachment style in patients with depression
    Barbara Costa
    Department of Human Morphology and Applied Biology, University of Pisa, Via Volta, 4 56126 Pisa, Italy
    Psychoneuroendocrinology 34:1506-14. 2009
  10. ncbi Platelet uptake of GABA and glutamate in patients with bipolar disorder
    Simona Daniele
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Bipolar Disord 14:301-8. 2012

Detail Information

Publications41

  1. ncbi Awareness of illness in patients with bipolar I disorder with or without comorbid anxiety disorders
    Stefano Pini
    Department of Psychiatry, Pharmacology, Neurobiology and Bio technology, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Aust N Z J Psychiatry 37:355-61. 2003
    ....
  2. ncbi [Approach to bipolar spectrum and subthreshold mood disorders]
    Stefano Pini
    Dipartimento di Psichiatria, Neurobiologia, Universita di Pisa, Pisa, Italy
    Riv Psichiatr 46:233-41. 2011
    ..However, regardless of the efforts made so far, a gap in classification still remains, putting restrictions in the clinical and neurobiological range of activities...
  3. ncbi Prevalence and burden of bipolar disorders in European countries
    Stefano Pini
    Department of Psychiatry, University of Pisa, Via Roma, 67 56100, Pisa, Italy
    Eur Neuropsychopharmacol 15:425-34. 2005
    ..Most studies suggest equally high or even higher levels of impairments and disabilities of bipolar disorders as compared to major depression and schizophrenia. Few data are available on treatment and health care utilization...
  4. ncbi Clinical correlates and significance of separation anxiety in patients with bipolar disorder
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, School of Medicine, University of Pisa, Pisa, Italy
    Bipolar Disord 7:370-6. 2005
    ....
  5. ncbi Treatment of depression with comorbid anxiety disorders: differential efficacy of paroxetine versus moclobemide
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Int Clin Psychopharmacol 18:15-21. 2003
    ..However, in the subgroup with comorbid panic disorder, paroxetine is more effective than moclobemide in reducing both depressive and anxiety symptoms...
  6. ncbi Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychobiology 52:83-9. 2005
    ..These results support the hypothesis that the COMT Val(158)Met polymorphism influences executive functions in schizophrenia and the neuromotor performance in the deficit subtype only...
  7. ncbi The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals
    Barbara Costa
    Department of Human Morphology and Applied Biology, University of Pisa, 4 56126 Pisa, Italy
    Endocrinology 150:5438-45. 2009
    ....
  8. ncbi Reductions in platelet 18-kDa translocator protein density are associated with adult separation anxiety in patients with bipolar disorder
    Marianna Abelli
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Neuropsychobiology 62:98-103. 2010
    ..The aim of this study was to explore whether adult separation anxiety might be a factor differentiating TSPO expression in a sample of patients with bipolar disorder...
  9. ncbi Oxytocin receptor polymorphisms and adult attachment style in patients with depression
    Barbara Costa
    Department of Human Morphology and Applied Biology, University of Pisa, Via Volta, 4 56126 Pisa, Italy
    Psychoneuroendocrinology 34:1506-14. 2009
    ..These findings support the involvement of the oxytocinergic system in the mechanisms that underlie depression and specific adult attachment styles...
  10. ncbi Platelet uptake of GABA and glutamate in patients with bipolar disorder
    Simona Daniele
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Bipolar Disord 14:301-8. 2012
    ..We explored the functionality of the GABA and Glu transporters in three groups of patients with BD, each with a different polarity of index episode (manic, depressive, or euthymic) at the time of blood draw...
  11. ncbi Different temperament and character dimensions correlate with panic disorder comorbidity in bipolar disorder and unipolar depression
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    J Anxiety Disord 22:1421-6. 2008
    ..This study aimed to investigate temperament and character correlates of panic disorder (PD) comorbidity in euthymic patients with bipolar disorder (BD) or unipolar depression (UD)...
  12. ncbi Patterns of structural MRI abnormalities in deficit and nondeficit schizophrenia
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Schizophr Bull 34:393-401. 2008
    ..These findings do not support the hypothesis that DS is the extreme end of a severity continuum within schizophrenia...
  13. ncbi Distinguishing affective depersonalization from anhedonia in major depression and bipolar disorder
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, 56100 Pisa, Italy
    Compr Psychiatry 51:187-92. 2010
    ....
  14. ncbi Cross-sectional similarities and differences between schizophrenia, schizoaffective disorder and mania or mixed mania with mood-incongruent psychotic features
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, via Roma 65, 56100 Pisa, Italy
    Eur Psychiatry 19:8-14. 2004
    ..The cross-sectional clinical differentiation of schizophrenia or schizoaffective disorder from mood-incongruent psychotic mania or mixed mania is difficult, since pathognomonic symptoms are lacking in these conditions...
  15. ncbi Mutation analysis of oxytocin gene in individuals with adult separation anxiety
    Barbara Costa
    Department of Human Morphology and Applied Biology, University of Pisa, Via Volta 4, 56126 Pisa, Italy
    Psychiatry Res 168:87-93. 2009
    ..Further research is needed to investigate the association between ASAD and OT peptide and receptor polymorphisms...
  16. ncbi The role of psychomotor activation in discriminating unipolar from bipolar disorders: a classification-tree analysis
    Giovanni B Cassano
    Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnology, School of Medicine, University of Pisa, Pisa, Italy
    J Clin Psychiatry 73:22-8. 2012
    ..The aim of the present report is to determine which combination of clinical, demographic, and psychopathological factors and corresponding cutoff scores best discriminate patients with unipolar disorder from those with bipolar disorders...
  17. ncbi Clinical correlates of depersonalization symptoms in patients with bipolar disorder
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Italy
    J Affect Disord 115:252-6. 2009
    ....
  18. ncbi Insight into illness in patients with mania, mixed mania, bipolar depression and major depression with psychotic features
    Liliana Dell'Osso
    Department of Psychiatry, Pharmacology, Neurobiology and, Biotechnology, University of Pisa, Pisa, Italy
    Bipolar Disord 4:315-22. 2002
    ..We also wanted to examine whether group differences in insight exist among bipolar manic, mixed and unipolar depressed patients with psychotic features...
  19. ncbi Social anxiety disorder comorbidity in patients with bipolar disorder: a clinical replication
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, via Roma 65, I-56100 Pisa, Italy
    J Anxiety Disord 20:1148-57. 2006
    ..These findings may influence treatment planning and the possibility of discovering a pathophysiological relationship between SAD and bipolarity...
  20. ncbi Platelet 18 kDa Translocator Protein density is reduced in depressed patients with adult separation anxiety
    Beatrice Chelli
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Via Bonanno 6, 56100 Pisa, Italy
    Eur Neuropsychopharmacol 18:249-54. 2008
    ....
  21. ncbi Validity and reliability of the Structured Clinical Interview for Depersonalization-Derealization Spectrum (SCI-DER)
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Italy
    Neuropsychiatr Dis Treat 4:977-86. 2008
    ..It significantly discriminated subjects with any diagnosis of mood and anxiety disorders from controls and subjects with depersonalization disorder from controls. The hypothesized structure of the instrument was confirmed empirically...
  22. ncbi The relationship between adult separation anxiety disorder and complicated grief in a cohort of 454 outpatients with mood and anxiety disorders
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, via Roma 65, I 56100 Pisa, Italy Electronic address
    J Affect Disord 143:64-8. 2012
    ..The aim of this study was to evaluate the relationship between ASAD and CG in a large cohort of outpatients with mood and anxiety disorders...
  23. ncbi Health-related quality of life and functioning in remitted bipolar I outpatients
    Armando Piccinni
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, 56127 Pisa, Italy
    Compr Psychiatry 48:323-8. 2007
    ..An affectively biased cognition may explain the gap between patient's perception of functioning and estimated functional adjustment, as assessed by clinicians...
  24. ncbi Six-month open trial of haloperidol as an adjunctive treatment for anorexia nervosa: a preliminary report
    Giovanni B Cassano
    Department of Psychiatry, School of Medicine, University of Pisa, Pisa, Italy
    Int J Eat Disord 33:172-7. 2003
    ..To evaluate the effectiveness of haloperidoll as an adjunctive treatment for resistant anorexia nervosa restricting subtype (AN-R)...
  25. ncbi Efficacy of ECT in depression: a meta-analytic review
    Daniel Pagnin
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology University of Pisa, Italy
    J ECT 20:13-20. 2004
    ..Data analyzed suggest that ECT is a valid therapeutic tool for treatment of depression, including severe and resistant forms...
  26. ncbi The role of newer antiglutamatergic agents as mood-stabilizers in bipolar disorder
    Marianna Abelli
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Pisa, Italy
    Curr Drug Targets 6:607-14. 2005
    ..These agents have widely varying mechanisms of action. Some of these medications focus on the current understanding of antiglutamatergic mechanisms of action and their treatment implications for bipolar disorders...
  27. ncbi Subthreshold mania as predictor of depression during interferon treatment in HCV+ patients without current or lifetime psychiatric disorders
    Stefano Pini
    Department of Psychiatry, University of Pisa, Pisa, Italy
    J Psychosom Res 62:349-55. 2007
    ..We analyzed the impact of lifetime manic-hypomanic symptoms and anxiety on the development of depression in hepatitis-C-virus-infected subjects treated with two different types of IFN-alpha...
  28. ncbi The neurobiology and clinical significance of depersonalization in mood and anxiety disorders: a critical reappraisal
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, Section of Psychiatry, University of Pisa, Via Roma, 67 56100 Pisa, Italy
    J Affect Disord 99:91-9. 2007
    ....
  29. ncbi Pramipexole in treatment-resistant depression: a 16-week naturalistic study
    Lorenzo Lattanzi
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Italy
    Bipolar Disord 4:307-14. 2002
    ..To assess the antidepressant efficacy and tolerability of adjunctive pramipexole, a D2-D3 dopamine agonist, in patients with drug-resistant depression...
  30. ncbi The role of anticonvulsant drugs in anxiety disorders: a critical review of the evidence
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Pisa, Italy
    J Clin Psychopharmacol 27:263-72. 2007
    ..Further investigation is needed to determine in what circumstances they should be used in individuals who are partially responsive or nonresponsive to conventional therapy...
  31. ncbi Oxcarbazepine as add-on treatment in patients with bipolar manic, mixed or depressive episode
    Alessandra Benedetti
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    J Affect Disord 79:273-7. 2004
    ..Despite several limitations, our study suggests the potential usefulness of OXC as adjunctive therapy to lithium both in acute and long-term treatment of bipolar disorder...
  32. ncbi Conceptual underpinnings and empirical support for the mood spectrum
    Giovanni B Cassano
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Psychiatr Clin North Am 25:699-712, v. 2002
    ..Finally, they summarize the clinical utility of such an approach to the description and assessment of patients with mood disorders...
  33. ncbi COMT Val(158)Met and BDNF C(270)T polymorphisms in schizophrenia: a case-control study
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie 1, 80138 Naples, Italy
    Schizophr Res 73:27-30. 2005
    ..These results do not support the hypothesis that the COMT Val(158)Met or BDNF C(270)T gene polymorphisms are associated with liability to schizophrenia...
  34. ncbi The role of quetiapine in the treatment of bipolar disorder
    Stefano Pini
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Expert Opin Pharmacother 7:929-40. 2006
    ..Sedation is the main side effect of treatment with quetiapine...
  35. ncbi The psychotic spectrum: a community-based study
    Alessandra Benedetti
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    World Psychiatry 8:110-4. 2009
    ..The three groups' scores did not significantly differ on instruments that assessed dimensionally psychotic and affective symptoms during the previous month...
  36. ncbi What Did We Learn from Research on Comorbidity In Psychiatry? Advantages and Limitations in the Forthcoming DSM-V Era
    Liliana Dell'Osso
    Department of Psychiatry, University of Pisa, Pisa, Italy
    Clin Pract Epidemiol Ment Health 8:180-4. 2012
    ..This should certainly be regarded as a positive development. Parallel, continuous critical challenge seems to be vital in this area, in order to prevent dangerous trivializations and misunderstandings...
  37. ncbi Awareness of disorder and suicide risk in the treatment of schizophrenia: results of the international suicide prevention trial
    Marc Bourgeois
    Psychopathology Research Laboratory, University of Bordeaux, 3 ter, Place de la Victoire, 33076 Bordeaux, France
    Am J Psychiatry 161:1494-6. 2004
    ..The complex interactions and mediation effects of these clinical variables require careful monitoring...
  38. ncbi Subthreshold psychiatric disorders in primary care: prevalence and associated characteristics
    Paola Rucci
    Instituto di Psichiatria, Universita de Bologna, Bologna, Italy
    J Affect Disord 76:171-81. 2003
    ..The authors analyse the prevalence of subthreshold psychiatric disorders in primary care and their association with the patient's health perception, disability in daily activities and psychological distress...
  39. ncbi Historical, psychopathological, neurological, and neuropsychological aspects of deficit schizophrenia: a multicenter study
    Silvana Galderisi
    University of Naples Department of Psychiatry, Italy
    Am J Psychiatry 159:983-90. 2002
    ....
  40. ncbi Peripheral-type benzodiazepine receptor binding sites in platelets of patients with panic disorder associated to separation anxiety symptoms
    Stefano Pini
    Psychopharmacology (Berl) 181:407-11. 2005
    ..CONCLUSIONS: Patients with SA symptoms had significantly lower densities of PBRs. PBR expression might become a useful biological marker of these two associated conditions...
  41. ncbi Cost of disorders of the brain in Italy
    Maura Pugliatti
    Dipartimento di Neuroscienze e Scienze Materno Infantili, Universita di Sassari, Viale San Pietro 10, 07100, Sassari, Italy
    Neurol Sci 29:99-107. 2008
    ..This figure is however likely to be underestimated as it is based on retrospective methodology and samples of brain disorders, and does not include intangible costs...