Sara Pignatelli

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi request reprint Development of a multiplex PCR for the simultaneous amplification and genotyping of glycoprotein N among human cytomegalovirus strains
    Sara Pignatelli
    Department of Haematology, Oncology and Laboratory Medicine, Clinical Unit of Microbiology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    New Microbiol 33:257-62. 2010
  2. ncbi request reprint gpUL73 (gN) genomic variants of human cytomegalovirus isolates are clustered into four distinct genotypes
    S Pignatelli
    Department of Clinical and Experimental Medicine, Division of Microbiology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy
    J Gen Virol 82:2777-84. 2001
  3. ncbi request reprint Latency-associated human cytomegalovirus glycoprotein N genotypes in monocytes from healthy blood donors
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division Microbiology, St Orsola General Hospital, University of Bologna, Bologna, Italy
    Transfusion 46:1754-62. 2006
  4. ncbi request reprint Genetic polymorphisms among human cytomegalovirus (HCMV) wild-type strains
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division of Microbiology St Orsola General Hospital, University of Bologna, Italy
    Rev Med Virol 14:383-410. 2004
  5. ncbi request reprint Monitoring for human cytomegalovirus infection in solid organ transplant recipients through antigenemia and glycoprotein N (gN) variants: evidence of correlation and potential prognostic value of gN genotypes
    Giada Rossini
    Department of Clinical and Experimental Medicine, Microbiology Division, St Orsola General Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Microbes Infect 7:890-6. 2005
  6. doi request reprint Very low birth weight infants born to cytomegalovirus-seropositive mothers fed with their mother's milk: a prospective study
    Maria Grazia Capretti
    Department of Obstetrical, Gynecological, and Pediatric Sciences, Operative Unit of Neonatology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    J Pediatr 154:842-8. 2009
  7. ncbi request reprint Intrauterine cytomegalovirus infection and glycoprotein N (gN) genotypes
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division Microbiology, St Orsola General Hospital, University of Bologna, Via Massarenti 9, Bologna, Italy
    J Clin Virol 28:38-43. 2003
  8. doi request reprint Cytomegalovirus gN genotypes distribution among congenitally infected newborns and their relationship with symptoms at birth and sequelae
    Sara Pignatelli
    Department of Haematology, Oncology and Laboratory Medicine, Clinical Unit of Microbiology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    Clin Infect Dis 51:33-41. 2010
  9. ncbi request reprint Genomic variants among human cytomegalovirus (HCMV) clinical isolates: the glycoprotein n (gN) paradigm
    Paola Dal Monte
    Department of Clinical and Experimental Medicine, St Orsola General Hospital, University of Bologna, Bologna, Italy
    Hum Immunol 65:387-94. 2004
  10. ncbi request reprint Cytomegalovirus infection via mother's milk: could distinct virus strains determine different disease patterns in preterm twins?
    Marcello Lanari
    Department of Gynecological, Ostetrical and Pediatric Sciences, Clinical Unit of Neonatology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    New Microbiol 31:131-5. 2008

Detail Information

Publications15

  1. ncbi request reprint Development of a multiplex PCR for the simultaneous amplification and genotyping of glycoprotein N among human cytomegalovirus strains
    Sara Pignatelli
    Department of Haematology, Oncology and Laboratory Medicine, Clinical Unit of Microbiology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    New Microbiol 33:257-62. 2010
    ..This novel approach will reduce costs and shorten the detection time of gN polymorphisms among HCMV clinical isolates...
  2. ncbi request reprint gpUL73 (gN) genomic variants of human cytomegalovirus isolates are clustered into four distinct genotypes
    S Pignatelli
    Department of Clinical and Experimental Medicine, Division of Microbiology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy
    J Gen Virol 82:2777-84. 2001
    ..gpUL73 hypervariability is not randomly distributed, but the identified genomic variants are clearly clustered into four distinct genotypes (gN-1, gN-2, gN-3 and gN-4), which are not associated with the gB subtype...
  3. ncbi request reprint Latency-associated human cytomegalovirus glycoprotein N genotypes in monocytes from healthy blood donors
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division Microbiology, St Orsola General Hospital, University of Bologna, Bologna, Italy
    Transfusion 46:1754-62. 2006
    ..HCMV UL73 encodes the polymorphic envelope glycoprotein N (gN), which shows seven genotypes (gN-1, gN-2, gN-3a, gN-3b, gN-4a, gN-4b, and gN-4c)...
  4. ncbi request reprint Genetic polymorphisms among human cytomegalovirus (HCMV) wild-type strains
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division of Microbiology St Orsola General Hospital, University of Bologna, Italy
    Rev Med Virol 14:383-410. 2004
    ....
  5. ncbi request reprint Monitoring for human cytomegalovirus infection in solid organ transplant recipients through antigenemia and glycoprotein N (gN) variants: evidence of correlation and potential prognostic value of gN genotypes
    Giada Rossini
    Department of Clinical and Experimental Medicine, Microbiology Division, St Orsola General Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Microbes Infect 7:890-6. 2005
    ..Reported data further support a role for gN genotypes in HCMV pathogenesis. gN-1 and gN-4b show a significantly different virulence and could serve as early predictors for the progression of HCMV infection in transplant patients...
  6. doi request reprint Very low birth weight infants born to cytomegalovirus-seropositive mothers fed with their mother's milk: a prospective study
    Maria Grazia Capretti
    Department of Obstetrical, Gynecological, and Pediatric Sciences, Operative Unit of Neonatology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    J Pediatr 154:842-8. 2009
    ..To assess the risk of post-natal cytomegalovirus (CMV) transmission to very low birth weight (VLBW) infants fed with their mother's fresh milk...
  7. ncbi request reprint Intrauterine cytomegalovirus infection and glycoprotein N (gN) genotypes
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division Microbiology, St Orsola General Hospital, University of Bologna, Via Massarenti 9, Bologna, Italy
    J Clin Virol 28:38-43. 2003
    ..One recently discovered polymorphic gene is ORF UL73, encoding for the envelope glycoprotein gN. Among HCMV clinical strains, it shows four distinct genomic variants denoted as gN-1, gN-2, gN-3 and gN-4...
  8. doi request reprint Cytomegalovirus gN genotypes distribution among congenitally infected newborns and their relationship with symptoms at birth and sequelae
    Sara Pignatelli
    Department of Haematology, Oncology and Laboratory Medicine, Clinical Unit of Microbiology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    Clin Infect Dis 51:33-41. 2010
    ..This study aimed to ascertain the role of gN variants as markers of pathogenicity and prognosis in newborns congenitally infected with CMV...
  9. ncbi request reprint Genomic variants among human cytomegalovirus (HCMV) clinical isolates: the glycoprotein n (gN) paradigm
    Paola Dal Monte
    Department of Clinical and Experimental Medicine, St Orsola General Hospital, University of Bologna, Bologna, Italy
    Hum Immunol 65:387-94. 2004
    ..This overview on gN clustered polymorphisms should be useful as a prototype model for a better understanding of the biologic and clinical relevance of HCMV clinical isolates genetic variability...
  10. ncbi request reprint Cytomegalovirus infection via mother's milk: could distinct virus strains determine different disease patterns in preterm twins?
    Marcello Lanari
    Department of Gynecological, Ostetrical and Pediatric Sciences, Clinical Unit of Neonatology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    New Microbiol 31:131-5. 2008
    ..These isolates were differentially transmitted to each of the twins and this may be responsible of the different patterns of disease...
  11. ncbi request reprint Human cytomegalovirus glycoprotein N genotypes in AIDS patients
    Sara Pignatelli
    Department of Clinical and Experimental Medicine, Division of Microbiology, St Orsola General Hospital, University of Bologna, Italy
    AIDS 17:761-3. 2003
  12. ncbi request reprint Epidemiology of human cytomegalovirus strains through comparison of methodological approaches to explore gN variants
    Sara Pignatelli
    Department of Haematology, Oncology and Laboratory Medicine, Clinical Unit of Microbiology, St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy
    New Microbiol 32:1-10. 2009
    ..This paper analyses the epidemiology of HCMV strains through analysis of gN variants, criticizing the methodological approaches and study populations by comparison of published reports...
  13. doi request reprint Remodelling of the nuclear lamina during human cytomegalovirus infection: role of the viral proteins pUL50 and pUL53
    Daria Camozzi
    Department of Clinical and Experimental Medicine, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    J Gen Virol 89:731-40. 2008
    ..These results suggest that pUL50 and pUL53 may play an important role in the exit of virions from the nucleus by inducing structural modifications of the nuclear lamina...
  14. ncbi request reprint [Recent knowledge on the linkage of strain specific genotypes with clinical manifestations of human citomegalovirus disease]
    Sara Pignatelli
    Sezione di Microbiologia, Dipartimento di Ematologia e Scienze Oncologiche L e A Seragnoli, Ospedale Sant Orsola Malpighi, Bologna
    Recenti Prog Med 102:5-10. 2011
    ..This paper aims to critically analyse the results of these studies and evaluate the linkage of strain-specific genotypes with clinical manifestations of CMV disease and their perspective implications...
  15. doi request reprint Different clinical manifestations of HCMV infection in preterm twins: methodological approach
    Marcello Lanari
    Pediatr Int 50:141; author reply 142. 2008