Research Topics
| M PifferiSummaryAffiliation: University of Pisa Country: Italy Publications
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Detail Information
Publications
Evaluation of pulmonary disease using static lung volumes in primary ciliary dyskinesiaMassimo Pifferi
University of Pisa, Department of Pediatrics, Via Roma 67, Pisa 56126, Italy
Thorax 67:993-9. 2012..In primary ciliary dyskinesia (PCD) lung damage is usually evaluated by high-resolution CT (HRCT)...
High torquetenovirus loads are correlated with bronchiectasis and peripheral airflow limitation in childrenMassimo Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy
Pediatr Infect Dis J 25:804-8. 2006..Correlations between TTV loads and severity of bronchiectasis and between TTV loads and lung function were evaluated...- Nasal nitric oxide in atypical primary ciliary dyskinesiaMassimo Pifferi
University of Pisa, Department of Pediatrics, Via Roma 67, 56122 Pisa, Italy
Chest 131:870-3. 2007..Atypical cases of primary ciliary dyskinesia (PCD) may present with minimal transmission electron microscopy (TEM) defects. The diagnostic role of nasal nitric oxide (nNO) levels was evaluated in those patients... - Bronchiectasis in children with recurrent pneumonia: an immunopathological damage associated with secondary ciliary dysmotilityM Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy
Int J Immunopathol Pharmacol 21:215-9. 2008..Whether ciliary dysmotility is a cause or a consequence of anatomical lesion is a matter of speculation. Very likely there is an amplification and self-maintaining mechanism between the two events which may lead to more serious disease... - Exhaled air temperature in asthmatic children: a mathematical evaluationMassimo Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy
Pediatr Allergy Immunol 20:164-71. 2009..Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway... - Torquetenovirus infection and ciliary dysmotility in children with recurrent pneumoniaMassimo Pifferi
Department of Pediatrics, Division of Surgical, Molecular and Ultrastructural Pathology, University of Pisa, Pisa, Italy
Pediatr Infect Dis J 27:413-8. 2008.... - Simplified cell culture method for the diagnosis of atypical primary ciliary dyskinesiaM Pifferi
Department of Pediatrics, University of Pisa, Via Roma 67, 56126 Pisa, Italy
Thorax 64:1077-81. 2009..The diagnosis of primary ciliary dyskinesia (PCD) can be challenging, and it may be particularly difficult to distinguish primary ciliary disease from the secondary changes after infections... - Health-related quality of life and unmet needs in patients with primary ciliary dyskinesiaM Pifferi
Dept of Paediatrics, University of Pisa, Pisa, Italy
Eur Respir J 35:787-94. 2010..PCD is associated with a progressive and continuous impact on the physical and mental health of the patients. Earlier identification of the patients and better strategies aimed at improving compliance with care are urgently needed... - Agenesis of paranasal sinuses and nasal nitric oxide in primary ciliary dyskinesiaM Pifferi
Dept of Paediatrics, University of Pisa, Via Roma 67 56126, Pisa, Italy
Eur Respir J 37:566-71. 2011..008, r = -0.432) but not in SCD (p = 0.07, r = -0.271). The findings of aplasia/hypoplasia of the frontal and or sphenoidal sinuses may be part of the spectrum of PCD and this finding should prompt exclusion of this condition... - Monitoring asthma control in children with allergies by soft computing of lung function and exhaled nitric oxideMassimo Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy, Pisa, Italy
Chest 139:319-27. 2011.... - Nasal nitric oxide and nitric oxide synthase expression in primary ciliary dyskinesiaM Pifferi
Dept of Pediatrics, University of Pisa, Via Roma 67, 56126 Pisa, Italy
Eur Respir J 37:572-7. 2011..045). These results demonstrate a relationship between nNO level, NOS mRNA expression and ciliary beat frequency... - Eosinophil cationic protein in infants with respiratory syncytial virus bronchiolitis: predictive value for subsequent development of persistent wheezingM Pifferi
Department of Pediatrics, University of Pisa, Italy
Pediatr Pulmonol 31:419-24. 2001..0001). In conclusion, our study suggests that s-ECP levels in infants with bronchiolitis are useful in predicting the risk to develop wheezing in the subsequent 5 years... - Blood gas analysis and chest x-ray findings in infants and preschool children with acute airway obstructionMassimo Pifferi
Department of Pediatric, University of Pisa, Italy
Respiration 72:176-81. 2005..The importance of SaO2 in the assessment of respiratory distress in bronchial asthma has been reported... - Montelukast and airway remodeling in children with chronic persistent asthma: an open studyMassimo Pifferi
Department of Pediatrics, University of Pisa, Via Roma 67, 56100 Pisa, Italy
Pediatr Allergy Immunol 15:472-3. 2004..Improvement of lung function with disappearance of low-density areas in six patients after treatment with fluticasone and montelukast was obtained... - Primary ciliary dyskinesia: diagnosis in children with inconclusive ultrastructural evaluationM Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy
Pediatr Allergy Immunol 12:274-82. 2001..These children were considered to be affected by PCD. Our study describes a method for the diagnosis of PCD in the absence of specific ultrastructural defects or when these defects are present in only a small proportion of the cilia... - "Cyst-like" structures within the ciliary shafts in children with bronchiectasisM Pifferi
Dept of Pediatrics, University of Pisa, Pisa, Italy
Eur Respir J 23:857-60. 2004..In contrast to one previous report, the reversibility of the defect suggests its secondary origin, which is most likely related to chronic airway inflammation... - Benefits of immunotherapy with a standardized Dermatophagoides pteronyssinus extract in asthmatic children: a three-year prospective studyM Pifferi
Departments of Pediatrics, University of Pisa, Italy
Allergy 57:785-90. 2002..CONCLUSIONS: Our results confirm that SIT is effective in asthmatic children sensitive to mites. It is associated with a decrease in BHR and it may prevent the development of new sensitizations in monosensitized subjects... - Associations between nasal torquetenovirus load and spirometric indices in children with asthmaMassimo Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy
J Infect Dis 192:1141-8. 2005..These findings are the first report of TTV infection status in children with asthma and suggest that TTV might be a contributing factor in the lung impairment caused by this condition... 
TT virus in the nasal secretions of children with acute respiratory diseases: relations to viremia and disease severityFabrizio Maggi
Virology Section and Retrovirus Center, Department of Experimental Pathology, University of Pisa, Via San Zeno 37, I-56127 Pisa, Italy
J Virol 77:2418-25. 2003..Furthermore, group 4 TTV was detected almost exclusively in children with BP...- A descriptive study of non-cystic fibrosis bronchiectasis in a pediatric population from central and southern ItalyFrancesca Santamaria
Department of Pediatrics, Federico II University, Naples, Italy
Respiration 77:160-5. 2009..Non-cystic fibrosis (CF) bronchiectasis is now identified more often than in the past... - Correlation between Torque tenovirus infection and serum levels of eosinophil cationic protein in children hospitalized for acute respiratory diseasesFabrizio Maggi
Virology Section and Retrovirus Center, Department of Experimental Pathology, University of Pisa, Italy
J Infect Dis 190:971-4. 2004..The possible mechanisms whereby TTV infection might lead to augmented activity of eosinophils and the implications for pathogenesis are discussed... - Pediatric bronchiectasis: correlation of HRCT, ventilation and perfusion scintigraphy, and pulmonary function testingMassimo Pifferi
Department of Pediatrics, University of Pisa, Pisa, Italy
Pediatr Pulmonol 38:298-303. 2004..Ventilation/perfusion scans and lung functions are additive tools to understand the complexity of the disease process and to improve diagnosis and therapeutic strategies... - Human bocavirus in Italian patients with respiratory diseasesFabrizio Maggi
Virology Section and Retrovirus Center, Department of Experimental Pathology, University of Pisa, Via San Zeno 37, I 56127 Pisa, Italy
J Clin Virol 38:321-5. 2007..hBoV, a recently discovered parvovirus, can be present in the respiratory tract of patients with acute respiratory diseases (ARD), but its etiologic involvement in the underlying diseases is still uncertain... - TT virus loads and lymphocyte subpopulations in children with acute respiratory diseasesFabrizio Maggi
Virology Section and Retrovirus Center, Department of Experimental Pathology, University of Pisa, Italy
J Virol 77:9081-3. 2003..Thus, florid TTV replication might contribute to lymphocyte imbalances and, possibly, immunosuppressive effects, thus resembling related animal viruses... - Automated software for analysis of ciliary beat frequency and metachronal wave orientation in primary ciliary dyskinesiaGiulia Mantovani
Interdepartmental Research Center E Piaggio, Faculty of Engineering, University of Pisa, Via Diotisalvi, 2, 56126 Pisa, Italy
Eur Arch Otorhinolaryngol 267:897-902. 2010..It is concluded that the developed software could be a useful mean for PCD diagnosis... - Low-density areas on high-resolution computed tomograms in chronic pediatric asthmaMassimo Pifferi
Department of Pediatrics, University of Pisa, Italy
J Pediatr 141:104-8. 2002..84, P <.0001). CONCLUSIONS: Structural changes similar to emphysema are also present in asthmatic children. Our findings suggest that the persistence of increased RV may be used to identify subjects with low-density areas on HRCT... - Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in ItalyFabrizio Maggi
Virology Section, Department of Experimental Pathology, University of Pisa, Pisa, Italy
J Clin Microbiol 41:2987-91. 2003..The study indicates that hMPV is seen as commonly as other respiratory viruses, may be associated with severe respiratory disease in infants, can establish mixed infections with other respiratory viruses, and has a seasonal occurrence... - Coseasonal sublingual immunotherapy reduces the development of asthma in children with allergic rhinoconjunctivitisElio Novembre
Research Centre, Hospital San Pietro Fatebenefratelli, AFaR, Rome
J Allergy Clin Immunol 114:851-7. 2004..5-10.0) in the control subjects. CONCLUSIONS: Three years of coseasonal SLIT improves seasonal allergic rhinitis symptoms and reduces the development of seasonal asthma in children with hay fever... - Foreign body aspiration in childrenFabio Midulla
Department of Pediatric Emergency, University La Sapienza of Rome, Rome, Italy
Pediatr Int 47:663-8. 2005..The aim was to investigate the role of physical and radiological findings before bronchoscopy in the diagnosis of foreign body aspiration (FBA)...