Affiliation: University of Milano-Bicocca
Location: Monza, Italy
- Increased tissue factor pathway inhibitor and homocysteine in Alzheimer's diseaseFabrizio Piazza
Department of Neuroscience and Biomedical Technologies, University of Milano Bicocca, Monza MI, Italy
Neurobiol Aging 33:226-33. 2012..Therefore, TFPI may represent a candidate marker of endothelial damage in AD and might be used for the identification and monitoring of patients that would benefit from folate supplementation treatment...
- Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?Gloria Galimberti
Department of Neuroscience and Biomedical Technology, University of Milano Bicocca, Via Cadore 48, 20052 Monza MI, Italy
Clin Biochem 41:914-6. 2008..To identify the real number of hyperhomocysteinemic Alzheimer's patients who may benefit from homocysteine-lowering therapy...
- Cholinesterase inhibitor use is associated with increased plasma levels of anti-Aβ 1-42 antibodies in Alzheimer's disease patientsElisa Conti
Department of Neuroscience and Biomedical Technologies, University of Milano Bicocca, San Gerardo Hospital, Via Cadore 48, 20052 Monza MI, Italy
Neurosci Lett 486:193-6. 2010..We suggest that a strategy aimed at increasing the endogenous response against this peptide might represent an interesting therapeutic target to be further investigated...
- Ubiquitin regulates GGA3-mediated degradation of BACE1Eugene L Kang
Alzheimer s Disease Research Laboratory, Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA
J Biol Chem 285:24108-19. 2010..These findings indicate that levels of GGA3 tightly and inversely regulate BACE1 levels via interaction with ubiquitin sorting machinery...
- Alpha-synuclein nitration and autophagy response are induced in peripheral blood cells from patients with Parkinson diseaseAlessandro Prigione
Laboratory of Neurobiology, Department of Neuroscience and Biomedical Technologies, University of Milan Bicocca, Italy
Neurosci Lett 477:6-10. 2010..We discuss the relevance of these findings with respect to PD pathogenesis and biomarker development...
- Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiencyG Tibolla
Department of Pharmacological Sciences, Universita degli Studi di Milano, 20133 Milan, Italy
Atherosclerosis 210:78-87. 2010..Aim of this study was to investigate aortic atherosclerosis development in a mouse model with central nervous system (CNS) restricted beta-amyloid precursor protein (APP) overexpression...
- Increased soluble APPalpha, Abeta 1-42, and anti-Abeta 1-42 antibodies in plasma from down syndrome patientsElisa Conti
Department of Neuroscience and Biomedical Technologies, San Gerardo Hospital, University of Milano Bicocca, Monza, Italy
Alzheimer Dis Assoc Disord 24:96-100. 2010..Our results suggested sAPPalpha as a possible peripheral marker for the alteration in APP metabolism in DS and highlighted an alteration in anti-abeta antibodies, for the first time evaluated in plasma from DS subjects...
- Platelets might mediate the increase of plasma glutamate in acute ischemic stroke: relevance for early neurological deteriorationLucio Tremolizzo
Department of Neurology, San Gerardo Hospital, Monza, Italy
Med Hypotheses 73:553-4. 2009....
- Acute lipophilicity-dependent effect of intravascular simvastatin in the early phase of focal cerebral ischemiaS Beretta
Department of Neuroscience and Biomedical Technologies, University of Milano Bicocca, Monza, Italy
Neuropharmacology 60:878-85. 2011..Our findings suggest that intravascular-delivered simvastatin exerts an acute lipophilicity-dependent protective effect in the early phase of cerebral ischemia...
- Cerebrospinal fluid levels of BAFF and APRIL in untreated multiple sclerosisF Piazza
Department of Neuroscience and Biomedical Technologies, University of Milano Bicocca, Via Cadore 48, 20052, Monza MI, Italy
J Neuroimmunol 220:104-7. 2010....