Research Topics
Genomes and GenesSpecies | Giuseppe PerroneSummaryAffiliation: University Campus Bio-Medico Country: Italy Publications
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Detail Information
Publications
Breast-like vulvar lesion with concurrent breast cancer: a case report and critical literature reviewGiuseppe Perrone
Department of Anatomical Pathology, Università Campus Bio Medico di Roma, Via Alvaro del Portillo, 200, 00128 Roma, Italy
In Vivo 23:629-34. 2009..The main diagnostic criteria for differential diagnosis between primary or metastatic breast-like vulvar carcinoma are also discussed...- COX-2 expression in lobular in situ neoplasia of the breast: correlation with histopathological grading system according to the Tavassoli classificationG Perrone
Surgical Pathology, Oncology Unit, University Campus Bio Medico, La Sapienza University, Rome, Italy
Histopathology 51:33-9. 2007.... 
Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypesG Perrone
Department of Anatomical Pathology, Campus Bio Medico University, Via Alvaro del Portillo 200, Rome, Italy
Eur J Histochem 54:e38. 2010....- Immunohistochemistry and differential diagnosis of a solitary flat laryngeal xanthoma: a case reportGiuseppe Perrone
Surgical Pathology, Campus Bio Medico University, Rome, Italy
In Vivo 21:119-21. 2007..CD68, S-100 protein and cytokeratin immunoreactivities were investigated. Immuno-histochemically, foamy cells were positive for CD68, indicating a histiocytic origin... - Reelin expression in human prostate cancer: a marker of tumor aggressiveness based on correlation with gradeGiuseppe Perrone
Department of Surgical Pathology, Campus Bio Medico University, Rome, Italy
Mod Pathol 20:344-51. 2007..This suggests reelin may behave as a specific histological marker and may represent a useful biomarker to predict aggressive phenotypic behavior of prostatic cancer cells... 
Caveolin-1 expression in human breast lobular cancer progressionGiuseppe Perrone
Department of Anatomical Pathology, Università Campus Bio Medico di Roma, Rome, Italy
Mod Pathol 22:71-8. 2009....- COX-2 expression of ampullary carcinoma: correlation with different histotypes and clinicopathological parametersGiuseppe Perrone
Surgical Pathology, Campus Bio Medico University, Via Emilio Longoni, Rome, 83 00155, Italy
Virchows Arch 449:334-40. 2006..Furthermore, the high rate of COX-2 expression in the intestinal subtype of ampullary carcinoma may represent the rational for a histotype-tailored therapy targeting COX-2... - COX-2 expression in ampullary carcinoma: correlation with angiogenesis process and clinicopathological variablesG Perrone
Surgical Pathology, Campus Bio Medico University, Rome, Italy
J Clin Pathol 59:492-6. 2006..Objective: To investigate by immunohistochemistry the expression of COX-2 and the angiogenesis process in a series of primary untreated ampullary carcinomas... - COX-2 localization within plasma membrane caveolae-like structures in human lobular intraepithelial neoplasia of the breastGiuseppe Perrone
Surgical Pathology, Università Campus Bio Medico di Roma, Via Alvaro del Portillo, 200, 00128 Rome, Italy
Virchows Arch 451:1039-45. 2007..Because caveolae are rich in signaling molecules, this COX-2 compartment may play an important role in diverse breast cancer carcinogenesis processes... - Correlation of p53 and bcl-2 expression with vascular endothelial growth factor (VEGF), microvessel density (MVD) and clinico-pathological features in colon cancerG Perrone
Service of Histopathology, Campus Bio Medico University, Rome, Italy
Cancer Lett 208:227-34. 2004..0001 and P=0.009). Our data confirm the central role of VEGF in angiogenesis and suggest direct correlations among p53, bcl-2 and VEGF expression in colon cancer... - COX-2 expression in DCIS: correlation with VEGF, HER-2/neu, prognostic molecular markers and clinicopathological featuresG Perrone
Surgical Pathology, Campus Bio Medico University, Rome, Italy
Histopathology 46:561-8. 2005.... - Prognostic role of human equilibrative transporter 1 (hENT1) in patients with resected gastric cancerDaniele Santini
Medical Oncology, University Campus Bio Medico, Rome, Italy
J Cell Physiol 223:384-8. 2010..Immunohistochemistry for the hENT1 protein carries prognostic information in patients with resected gastric cancer and holds promise as a predictive factor in chemotherapy decisions... - PML as a potential predictive factor of oxaliplatin/fluoropyrimidine-based first line chemotherapy efficacy in colorectal cancer patientsBruno Vincenzi
Department of Oncology, University Campus Bio Medico, Rome, Italy
J Cell Physiol 227:927-33. 2012..This study represents the first evidence of a possible correlation between PML protein expression and outcome of metastatic colorectal cancer patients treated with oxaliplatin/fluoropyrimidine-based first line therapy... - Thymidylate synthase expression in normal colonic mucosa: a predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapyDaniele Santini
Medical Oncology Unit, University Campus Bio-Medico, Rome, Italy
Oncology 67:135-42. 2004..CONCLUSIONS: Immunohistochemical TS expression in normal colonic mucosa may represent an important predictive parameter for identifying a subset of patients with a high risk of developing severe 5-FU-related toxicities... - Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patientsDaniele Santini
Department of Medical Oncology, University Campus Bio Medico of Rome, Rome, Italy
PLoS ONE 6:e19234. 2011..RANKL stimulates migration of RANK-expressing tumor cells in vitro, conversely inhibited by OPG... - Carcinoma of the ampulla of vater: morphological and immunophenotypical classification predicts overall survivalSergio Morini
From the Units of Human Anatomy, Pathology, Surgery, and Oncology, CIR, Campus Bio Medico University of Rome, Rome, Italy Pathology Department, Catholic University of Rome, Rome, Italy and CeRMS, Molecular Oncology, University of Torino, Turin, Italy
Pancreas 42:60-6. 2013..The objective of the study was to verify if histopathological differentiation of ampullary carcinoma after surgical resection may be related to survival... - Toll-like receptor-4 expression by hepatic progenitor cells and biliary epithelial cells in HCV-related chronic liver diseaseUmberto Vespasiani-Gentilucci
Clinical Medicine and Hepatology Unit, University Campus Bio Medico of Rome, Rome, Italy
Mod Pathol 25:576-89. 2012..05) and inflammation (P<0.05). The present results suggest that TLR4 expression by hepatic progenitor cells and biliary epithelial cells contributes to the progression of liver damage in the course of chronic HCV-related infection... - An increase of CA 19.9 as the first clinical sign of ileocecal valve metastasis from breast cancerDaniele Santini
Department of Medical Oncology, University Campus Bio Medico, Rome, Italy
In Vivo 20:165-8. 2006..CONCLUSION: This is the first report in the literature of an ileocecal valve metastasis from breast cancer diagnosed by an increase of CA 19.9, which is a marker of primary colorectal carcinoma... - In situ identification of CD44+/CD24- cancer cells in primary human breast carcinomasGiuseppe Perrone
Department of Pathology, Campus Bio Medico University of Rome, Rome, Italy
PLoS ONE 7:e43110. 2012.... - Promyelocytic leukemia (PML) gene expression is a prognostic factor in ampullary cancer patientsB Vincenzi
Department of Medical Oncology, University Campus Bio Medico, Rome, Italy
Ann Oncol 20:78-83. 2009..Promyelocytic leukemia (PML) tumor suppressor gene plays a key role in acute PML pathogenesis but its involvement in pathogenesis and prognosis of solid cancers has not been defined yet... - Dynamic contrast enhanced magnetic resonance imaging of the terminal ileum: differentiation of activity of Crohn's diseaseRiccardo Del Vescovo
Department of Radiology, University Campus Bio Medico, Rome, Italy
Abdom Imaging 33:417-24. 2008..To prospectively investigate a new high resolution MRI technique for dynamic evaluation of the enhancement kinetics of bowel parietal layers and to correlate it with CDAI, CRP, endoscopic activity and histologic features... - Vocal cord metastasis from breast cancerRosario Francesco Grasso
Interdisciplinary Center for Biomedical Research, Department of Radiology, Otolaryngology-Head and Neck Surgery and Pathology, , Rome, Italy
J Clin Oncol 25:1803-5. 2007 - PML down-regulation in soft tissue sarcomasBruno Vincenzi
Department of Oncology, University Campus Bio Medico, Rome, Italy
J Cell Physiol 224:644-8. 2010..Further investigations are needed to confirm these data and to assess the possible value of PML expression as a prognostic factor in these extremely aggressive diseases... - Pleomorphic adenoma of the breastEnrico De Dominicis
Surgical Pathology, Senology Unit, University Campus Bio-Medico, Rome, Italy
Breast J 11:513-4. 2005 - Expression pattern of receptor activator of NFκB (RANK) in a series of primary solid tumors and related bone metastasesDaniele Santini
Department of Medical Oncology, University Campus Bio Medico, Rome, Italy
J Cell Physiol 226:780-4. 2011..These data highlight the central role of RANK/RANKL/OPG pathway as potential therapeutic target not only in bone metastasis management, but also in the adjuvant setting... - Cell cycle alterations and lung cancerB Vincenzi
Medical Oncology, Campus Bio Medico University, Rome, Italy
Histol Histopathol 21:423-35. 2006.... - Human equilibrative nucleoside transporter 1 (hENT1) protein is associated with short survival in resected ampullary cancerD Santini
Department of Medical Oncology, University Campus Bio Medico, via Emilio Longoni 81, 00155 Rome, Italy
Ann Oncol 19:724-8. 2008.... - Differential modulation of Ku70/80 DNA-binding activity in a patient with multiple basal cell carcinomasPaola Mazzarelli
Laboratory for Molecular Medicine and Biotechnology, Interdisciplinary Center for Biomedical Research, , Rome, Italy
J Invest Dermatol 121:628-33. 2003..001). Although these results are limited to only one patient, together with other recent studies they support the hypothesis that downregulation of the nonhomologous end-joining pathway may be associated with tumor progression... - High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practiceDaniele Santini
Department of Oncology, University Campus Bio Medico, Rome, Italy
Oncologist 13:1270-5. 2008..Nevertheless, most experiences were conducted on samples from primaries. The aim of this study was to evaluate the grade of concordance in terms of KRAS status between primaries and related metastases... - Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancerGiuseppe Perrone
Department of Histopathology, University Campus Biomedico, Rome, Italy
Eur J Cancer 44:1875-82. 2008..006). FOXP3-positive Tregs may be a novel marker for identifying high-risk gastric cancer patients. Present findings deserve additional investigation as Tregs may also represent an innovative therapeutic target... - Tumour proliferation, angiogenesis, and ploidy status in human colon cancerE Cristi
Surgical Pathology, Campus Bio-Medico University, Via Emilio Longoni, Rome 83 00155, Italy
J Clin Pathol 58:1170-4. 2005..Furthermore, the positive correlation between microvessel density, VEGF expression, and ploidy status provides more evidence that genetic alterations are involved in tumour angiogenesis... - Collagen changes in the ureteropelvic junction after failed antegrade endopyelotomyFederico Sergi
Urology Unit, Campus Bio Medico University of Rome, Rome, Italy
J Endourol 21:103-7. 2007..We evaluated the collagen content and differentiation of the ureteropelvic junction (UPJ) of patients who underwent Anderson-Hynes dismembered pyeloplasty after failure of antegrade endopyelotomy... - Solitary fibrous tumour of thyroid: report of two cases with immunohistochemical features and literature reviewGiuseppe Santeusanio
Dipartimento di Biopatologia e Diagnostica per Immagini, Sezione di Anatomia Patologica and UOC Anatomia Patologica, Universita degli Studi di Roma Tor Vergata, Ospedale S Eugenio, Piazzale dell Umanesimo n 10, Rome, Italy
Head Neck Pathol 2:231-5. 2008..However, the morphologic and immunohistochemical findings of SFT are so characteristic that this diagnosis seldom represent a difficulty... - Non-cirrhotic portal hypertension with large regenerative nodules: a diagnostic challengeUmberto Vespasiani Gentilucci
Clinical Medicine and Hepatology Unit, University Campus Bio Medico of Rome, 00128 Rome, Italy
World J Gastroenterol 17:2580-4. 2011..More flexibility in classification should derive from this etiopathogenic background... - Urinary complications from breast cancer metastasis: case report and review of the literatureE Vulcano
Department of Senology, Universita Campus BioMedico, Rome, Italy
G Chir 31:243-5. 2010..To date this is the seventh reported case of isolated metastatis of breast carcinoma to the bladder... - Subcellular shift of the hepatic growth hormone receptor with progression of hepatitis C virus-related chronic liver diseaseU Vespasiani Gentilucci
Internal Medicine and Hepatology Laboratory, Centre of Interdisciplinary Research CIR, Rome, Italy
Histopathology 48:822-30. 2006..To evaluate the cytoplasmic and nuclear expression of hepatic growth hormone receptor (GHR) in different stages (S0, S1, S3 and S4, according to Knodell's classification) of chronic liver disease (CLD) and in hepatocellular carcinoma (HCC)... - Intercellular space diameters of the oesophageal epithelium in NERD patients: head to head comparison between light and electron microscopy analysisM Ribolsi
Department of Digestive Diseases, Campus Bio Medico University, Rome, Italy
Dig Liver Dis 41:9-14. 2009..Semi-quantitative evaluation of intercellular space diameters using light microscopy seems to provide promising results... - Effects of either tibolone or continuous combined transdermal estradiol with medroxyprogesterone acetate on coagulatory factors and lipoprotein(a) in menopauseG Perrone
Department of Gynecology and Obstetrics, University Sapienza, Rome, Italy
Gynecol Obstet Invest 68:33-9. 2009..The aim of this prospective controlled study was to compare the effects of two therapies for menopause on factor VII (FVII) and hemostatic variables... - DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumorPaola Mazzarelli
Laboratory of Molecular Medicine and Biotechnology, , Via Longoni, 83, Rome 00155, Italy
World J Gastroenterol 11:6694-700. 2005..Since the NHEJ is an error prone mechanism, its abnormal activation can result in chromosomal instability and ultimately lead to tumorigenesis...