Research Topics
Genomes and Genes | Paolo PelosiSummaryAffiliation: University of Pisa Country: Italy Publications
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Publications
Binding of polycyclic aromatic hydrocarbons to mutants of odorant-binding protein: a first step towards biosensors for environmental monitoringYin Wei
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
Biochim Biophys Acta 1784:666-71. 2008....
The role of perireceptor events in vertebrate olfactionP Pelosi
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
Cell Mol Life Sci 58:503-9. 2001..Such similarities, together with anatomical and behavioural evidence, suggest that OBPs may be involved in the perception of pheromones...
Diversity of odorant-binding proteins and chemosensory proteins in insectsPaolo Pelosi
University of Pisa, Pisa, Italy and China Agricultural University, Beijing, China
Chem Senses 30:i291-2. 2005
Soluble proteins in insect chemical communicationP Pelosi
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa Italy, Agrarie via S Michele, 4, 56124, Pisa, Italy
Cell Mol Life Sci 63:1658-76. 2006..Finally, we discuss current ideas and models of the role of such proteins in insect chemoreception...
Odorant-binding proteins: structural aspectsP Pelosi
Istituto di Industrie Agrarie, University of Pisa, Italy
Ann N Y Acad Sci 855:281-93. 1998..In some cases the amino acid residues involved in ligand binding have been identified with the use of photoaffinity label analogues...
Differential expression of odorant-binding proteins in the mandibular glands of the honey bee according to caste and ageImmacolata Iovinella
Department of Biology of Agricultural Plants, University of Pisa, Pisa, Italy
J Proteome Res 10:3439-49. 2011..The high expression of different OBPs in the mandibular glands suggests that such proteins could be involved in solubilization and release of semiochemicals...
Plant stress proteins of the thaumatin-like family discovered in animalsAnna Brandazza
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Via S. Michele, 4, 56124 Pisa, Italy
FEBS Lett 572:3-7. 2004..A three-dimensional model of S. gregaria TLP suggests a glucanase function. As in plants, TLPs could play a defense role in insects against pathogens...
Chemosensory proteins of Locusta migratoriaL Ban
Department of Entomology, China Agricultural University, Beijing, China
Insect Mol Biol 12:125-34. 2003..One of these isoforms has been expressed in a bacterial system with high yield and used in a fluorescent binding assay. Competitive binding experiments have indicated the presence of long-chain compounds among the best ligands...
Amino acid sequence, post-translational modifications, binding and labelling of porcine odorant-binding proteinS Paolini
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
Chem Senses 23:689-98. 1998..These compounds together with other ligands were able to bind the protein as revealed by competitive binding experiments...
Cloning and expression of odorant-binding proteins Ia and Ib from mouse nasal tissueD Pes
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
Gene 212:49-55. 1998..In-situ hybridisation has revealed identical expression patterns for the two proteins, further supporting the heterodimeric structure of these proteins in the nasal mucus...
Soluble proteins of chemical communication in the social wasp Polistes dominulusM Calvello
Dipartimento di Chimica e Biotecnologie Agrarie, Via S. Michele 4, 56124 Pisa, Italy
Cell Mol Life Sci 60:1933-43. 2003..OBPs isolated from the wings were found to be associated with a number of long-chain aliphatic amides and other small organic molecules. Binding of these ligands and other related compounds was measured for both recombinant OBP and CSP...
Two odorant-binding proteins mediate the behavioural response of aphids to the alarm pheromone (E)-ß-farnesene and structural analoguesYu feng Sun
Dipartimento di Biologia delle Piante Agrarie, Pisa, Italy
PLoS ONE 7:e32759. 2012..Recently odorant-binding proteins (OBPs) have been shown to play a central role in olfactory recognition, thus becoming the target of choice for designing new semiochemicals...
Intriguing similarities between two novel odorant-binding proteins of locustsFang Yu
Department of Entomology, China Agricultural University, Beijing, China
Biochem Biophys Res Commun 385:369-74. 2009..In immunocytochemistry, antibodies against LmigOBP2 strongly stained the outer lymph of sensilla chaetica of the antennae, in contrast with LmigOBP1, previously reported in sensilla basiconica...
AIDS vaccination studies with an ex vivo feline immunodeficiency virus model: analysis of the accessory ORF-A protein and DNA as protective immunogensMauro Pistello
Dipartimento di Patologia Sperimentale, Universita di Pisa, Via San Zeno 37, I 56127 Pisa, Italy
J Virol 80:8856-68. 2006....
Biochemical characterization and bacterial expression of an odorant-binding protein from Locusta migratoriaL Ban
Department of Entomology, China Agricultural University, Beijing, China
Cell Mol Life Sci 60:390-400. 2003..This is the first report of an odorant-binding protein identified and characterized from Orthoptera...
The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognitionM A Bianchet
Department of Biophysics and Biophysical Chemistry, University of Pisa, Italy
Nat Struct Biol 3:934-9. 1996....
Lipocalins of boar salivary glands binding odours and pheromonesS Marchese
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
Eur J Biochem 252:563-8. 1998..The protein also binds 2-isobutyl-3-methoxypyrazine, a good ligand for most odorant-binding proteins, with a dissociation constant of 5 microM...
Secretory proteins as potential semiochemical carriers in the horseBarbara D'Innocenzo
Dipartimento di Chimica e Biotecnologie Agrarie, Universita di Pisa, 56124 Pisa, Italy
Biochemistry 45:13418-28. 2006..Binding experiments performed with a number of different organic compounds failed to identify ligands for this protein with a well-defined physiological role...
Binding properties of a locust's chemosensory proteinLiping Ban
Department of Entomology, China Agricultural University, Beijing, China
Biochem Biophys Res Commun 293:50-4. 2002..The ligand-binding characteristics of chemosensory proteins may help in clarifying the role of this recently discovered class of soluble proteins in chemoreception...
Cooperative interactions between odorant-binding proteins of Anopheles gambiaeHuili Qiao
Department of Biology and Agricultural Plants, University of Pisa, Via S Michele, 4, 56124, Pisa, Italy
Cell Mol Life Sci 68:1799-813. 2011..Confirmation of the likely role of heterodimers was demonstrated by in situ hybridisation, suggesting that OBP1 and OBP4 are co-expressed in some antennal sensilla of A. gambiae...
Expression in antennae and reproductive organs suggests a dual role of an odorant-binding protein in two sibling Helicoverpa speciesYa Lan Sun
State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
PLoS ONE 7:e30040. 2012....
Porcine VEG proteins and tear prealbuminsM Garibotti
Istituto di Industrie Agrarie, Pisa, Italy
Chem Senses 20:69-76. 1995..The two proteins appear to be identical, as in humans. The reason why the same protein is expressed in different tissues, as well as its physiological function, still remain to be clarified...
Expression of odorant-binding proteins and chemosensory proteins in some HymenopteraM Calvello
Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Via S. Michele, 4, 56124 Pisa, Italy
Insect Biochem Mol Biol 35:297-307. 2005..These data indicate that at least in some hymenopteran species CSPs are specifically expressed in antennae and could perform roles in chemosensory perception so far assigned only to OBPs...
Multiple functions of an odorant-binding protein in the mosquito Aedes aegyptiSha Li
Rothamsted NYNU Joint Laboratory, Nanyang Normal University, Nanyang, Henan, China Henan Normal University, Xinxiang, Henan, China
Biochem Biophys Res Commun 372:464-8. 2008..Antiserum against odorant-binding protein 22 also stained the edges and sensilla of spiracles, indicating a third, still unknown, role for this protein...
Solution structure of a chemosensory protein from the desert locust Schistocerca gregariaSimona Tomaselli
Department of Chemistry, University of Naples Federico II, 80126 Napoli, Italy
Biochemistry 45:10606-13. 2006..In fact, incubation of the protein with a natural ligand, namely, oleamide, produced substantial changes to the NMR spectra, suggesting extensive conformational transitions upon ligand binding...
Revisiting the odorant-binding protein LUSH of Drosophila melanogaster: evidence for odour recognition and discriminationJing Jiang Zhou
Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK
FEBS Lett 558:23-6. 2004....
Boar salivary lipocalin. Three-dimensional X-ray structure and androsterol/androstenone docking simulationsSilvia Spinelli
, , France
Eur J Biochem 269:2449-56. 2002..This explains the higher affinity of SAL for both steroid molecules compared to other smaller molecules, although no specific interaction is established with either compound...
Cloning of an olfactory sensory neuron-specific protein in the land snail (Eobania vermiculata)Andrea Mazzatenta
Dipartimento di Neurobiologia, Scuola Internazionale Superiore di Studi Avanzati, 34014 Trieste, Italy
Proc Biol Sci 271:S46-9. 2004..This protein could represent a plesiomorphic character in the evolution of olfactory proteins...
