Paolo Pelosi

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. doi request reprint Binding of polycyclic aromatic hydrocarbons to mutants of odorant-binding protein: a first step towards biosensors for environmental monitoring
    Yin Wei
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Biochim Biophys Acta 1784:666-71. 2008
  2. pmc Expression in antennae and reproductive organs suggests a dual role of an odorant-binding protein in two sibling Helicoverpa species
    Ya Lan Sun
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 7:e30040. 2012
  3. ncbi request reprint Soluble proteins in insect chemical communication
    P Pelosi
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa Italy, Agrarie via S Michele, 4, 56124, Pisa, Italy
    Cell Mol Life Sci 63:1658-76. 2006
  4. ncbi request reprint Diversity of odorant-binding proteins and chemosensory proteins in insects
    Paolo Pelosi
    University of Pisa, Pisa, Italy and China Agricultural University, Beijing, China
    Chem Senses 30:i291-2. 2005
  5. ncbi request reprint The role of perireceptor events in vertebrate olfaction
    P Pelosi
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Cell Mol Life Sci 58:503-9. 2001
  6. ncbi request reprint Odorant-binding proteins: structural aspects
    P Pelosi
    Istituto di Industrie Agrarie, University of Pisa, Italy
    Ann N Y Acad Sci 855:281-93. 1998
  7. pmc A lysine at the C-terminus of an odorant-binding protein is involved in binding aldehyde pheromone components in two Helicoverpa species
    Ya Lan Sun
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e55132. 2013
  8. ncbi request reprint Ligand-binding study of Anopheles gambiae chemosensory proteins
    Immacolata Iovinella
    Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto, 80, 56124 Pisa, Italy
    Chem Senses 38:409-19. 2013
  9. doi request reprint Odorant-binding proteins and olfactory coding in the solitary bee Osmia cornuta
    Xue Wei Yin
    Department of Agriculture, Food and Environment, University of Pisa, Pisa, Italy
    Cell Mol Life Sci 70:3029-39. 2013
  10. doi request reprint Three pheromone-binding proteins help segregation between two Helicoverpa species utilizing the same pheromone components
    Hao Guo
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, The Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, China
    Insect Biochem Mol Biol 42:708-16. 2012

Collaborators

Detail Information

Publications36

  1. doi request reprint Binding of polycyclic aromatic hydrocarbons to mutants of odorant-binding protein: a first step towards biosensors for environmental monitoring
    Yin Wei
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Biochim Biophys Acta 1784:666-71. 2008
    ....
  2. pmc Expression in antennae and reproductive organs suggests a dual role of an odorant-binding protein in two sibling Helicoverpa species
    Ya Lan Sun
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 7:e30040. 2012
    ....
  3. ncbi request reprint Soluble proteins in insect chemical communication
    P Pelosi
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa Italy, Agrarie via S Michele, 4, 56124, Pisa, Italy
    Cell Mol Life Sci 63:1658-76. 2006
    ..Finally, we discuss current ideas and models of the role of such proteins in insect chemoreception...
  4. ncbi request reprint Diversity of odorant-binding proteins and chemosensory proteins in insects
    Paolo Pelosi
    University of Pisa, Pisa, Italy and China Agricultural University, Beijing, China
    Chem Senses 30:i291-2. 2005
  5. ncbi request reprint The role of perireceptor events in vertebrate olfaction
    P Pelosi
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Cell Mol Life Sci 58:503-9. 2001
    ..Such similarities, together with anatomical and behavioural evidence, suggest that OBPs may be involved in the perception of pheromones...
  6. ncbi request reprint Odorant-binding proteins: structural aspects
    P Pelosi
    Istituto di Industrie Agrarie, University of Pisa, Italy
    Ann N Y Acad Sci 855:281-93. 1998
    ..In some cases the amino acid residues involved in ligand binding have been identified with the use of photoaffinity label analogues...
  7. pmc A lysine at the C-terminus of an odorant-binding protein is involved in binding aldehyde pheromone components in two Helicoverpa species
    Ya Lan Sun
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e55132. 2013
    ....
  8. ncbi request reprint Ligand-binding study of Anopheles gambiae chemosensory proteins
    Immacolata Iovinella
    Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto, 80, 56124 Pisa, Italy
    Chem Senses 38:409-19. 2013
    ..Their different affinities toward a set of pure chemicals suggest specific roles in chemical communication...
  9. doi request reprint Odorant-binding proteins and olfactory coding in the solitary bee Osmia cornuta
    Xue Wei Yin
    Department of Agriculture, Food and Environment, University of Pisa, Pisa, Italy
    Cell Mol Life Sci 70:3029-39. 2013
    ..cornuta. We have expressed all six OBPs of O. cornuta and studied their binding specificities. The best ligands are common terpene plant odorants and both volatiles produced by the bee and identified in this work. ..
  10. doi request reprint Three pheromone-binding proteins help segregation between two Helicoverpa species utilizing the same pheromone components
    Hao Guo
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, The Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, China
    Insect Biochem Mol Biol 42:708-16. 2012
    ..We suggest that all three PBPs might cooperate to build a unique olfactory image, that could help avoiding cross-mating between the two species and with other noctuids...
  11. ncbi request reprint Differential expression of odorant-binding proteins in the mandibular glands of the honey bee according to caste and age
    Immacolata Iovinella
    Department of Biology of Agricultural Plants, University of Pisa, Pisa, Italy
    J Proteome Res 10:3439-49. 2011
    ..The high expression of different OBPs in the mandibular glands suggests that such proteins could be involved in solubilization and release of semiochemicals...
  12. ncbi request reprint Plant stress proteins of the thaumatin-like family discovered in animals
    Anna Brandazza
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Via S Michele, 4, 56124 Pisa, Italy
    FEBS Lett 572:3-7. 2004
    ..A three-dimensional model of S. gregaria TLP suggests a glucanase function. As in plants, TLPs could play a defense role in insects against pathogens...
  13. ncbi request reprint Chemosensory proteins of Locusta migratoria
    L Ban
    Department of Entomology, China Agricultural University, Beijing, China
    Insect Mol Biol 12:125-34. 2003
    ..One of these isoforms has been expressed in a bacterial system with high yield and used in a fluorescent binding assay. Competitive binding experiments have indicated the presence of long-chain compounds among the best ligands...
  14. ncbi request reprint Cloning and expression of odorant-binding proteins Ia and Ib from mouse nasal tissue
    D Pes
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Gene 212:49-55. 1998
    ..In-situ hybridisation has revealed identical expression patterns for the two proteins, further supporting the heterodimeric structure of these proteins in the nasal mucus...
  15. ncbi request reprint Soluble proteins of chemical communication in the social wasp Polistes dominulus
    M Calvello
    Dipartimento di Chimica e Biotecnologie Agrarie, via S Michele 4, 56124 Pisa, Italy
    Cell Mol Life Sci 60:1933-43. 2003
    ..OBPs isolated from the wings were found to be associated with a number of long-chain aliphatic amides and other small organic molecules. Binding of these ligands and other related compounds was measured for both recombinant OBP and CSP...
  16. ncbi request reprint Amino acid sequence, post-translational modifications, binding and labelling of porcine odorant-binding protein
    S Paolini
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Chem Senses 23:689-98. 1998
    ..These compounds together with other ligands were able to bind the protein as revealed by competitive binding experiments...
  17. doi request reprint Diversity, abundance, and sex-specific expression of chemosensory proteins in the reproductive organs of the locust Locusta migratoria manilensis
    Xian Hong Zhou
    Department of Entomology, China Agricultural University, Beijing, China
    Biol Chem 394:43-54. 2013
    ..We cannot exclude that different functions can be associated with each of the 17 CSPs, including delivery of semiochemicals, solubilization of hormones, direct control of development, or other unknown tasks...
  18. pmc Two odorant-binding proteins mediate the behavioural response of aphids to the alarm pheromone (E)-ß-farnesene and structural analogues
    Yu feng Sun
    Dipartimento di Biologia delle Piante Agrarie, Pisa, Italy
    PLoS ONE 7:e32759. 2012
    ..Recently odorant-binding proteins (OBPs) have been shown to play a central role in olfactory recognition, thus becoming the target of choice for designing new semiochemicals...
  19. doi request reprint Intriguing similarities between two novel odorant-binding proteins of locusts
    Fang Yu
    Department of Entomology, China Agricultural University, Beijing, China
    Biochem Biophys Res Commun 385:369-74. 2009
    ..In immunocytochemistry, antibodies against LmigOBP2 strongly stained the outer lymph of sensilla chaetica of the antennae, in contrast with LmigOBP1, previously reported in sensilla basiconica...
  20. pmc AIDS vaccination studies with an ex vivo feline immunodeficiency virus model: analysis of the accessory ORF-A protein and DNA as protective immunogens
    Mauro Pistello
    Dipartimento di Patologia Sperimentale, Universita di Pisa, Via San Zeno 37, I 56127 Pisa, Italy
    J Virol 80:8856-68. 2006
    ....
  21. ncbi request reprint The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition
    M A Bianchet
    Department of Biophysics and Biophysical Chemistry, University of Pisa, Italy
    Nat Struct Biol 3:934-9. 1996
    ....
  22. ncbi request reprint Biochemical characterization and bacterial expression of an odorant-binding protein from Locusta migratoria
    L Ban
    Department of Entomology, China Agricultural University, Beijing, China
    Cell Mol Life Sci 60:390-400. 2003
    ..This is the first report of an odorant-binding protein identified and characterized from Orthoptera...
  23. ncbi request reprint Lipocalins of boar salivary glands binding odours and pheromones
    S Marchese
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Italy
    Eur J Biochem 252:563-8. 1998
    ..The protein also binds 2-isobutyl-3-methoxypyrazine, a good ligand for most odorant-binding proteins, with a dissociation constant of 5 microM...
  24. ncbi request reprint Unique function of a chemosensory protein in the proboscis of two Helicoverpa species
    Yu Ling Liu
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    J Exp Biol 217:1821-6. 2014
    ..On this basis, we suggest that CSP4 acts as a wetting agent to reduce the surface tension of aqueous solutions and consequently the pressure involved in sucking. ..
  25. doi request reprint Cooperative interactions between odorant-binding proteins of Anopheles gambiae
    Huili Qiao
    Department of Biology and Agricultural Plants, University of Pisa, Via S Michele, 4, 56124, Pisa, Italy
    Cell Mol Life Sci 68:1799-813. 2011
    ..Confirmation of the likely role of heterodimers was demonstrated by in situ hybridisation, suggesting that OBP1 and OBP4 are co-expressed in some antennal sensilla of A. gambiae...
  26. ncbi request reprint Secretory proteins as potential semiochemical carriers in the horse
    Barbara D'Innocenzo
    Dipartimento di Chimica e Biotecnologie Agrarie, Universita di Pisa, 56124 Pisa, Italy
    Biochemistry 45:13418-28. 2006
    ..Binding experiments performed with a number of different organic compounds failed to identify ligands for this protein with a well-defined physiological role...
  27. ncbi request reprint Binding properties of a locust's chemosensory protein
    Liping Ban
    Department of Entomology, China Agricultural University, Beijing, China
    Biochem Biophys Res Commun 293:50-4. 2002
    ..The ligand-binding characteristics of chemosensory proteins may help in clarifying the role of this recently discovered class of soluble proteins in chemoreception...
  28. ncbi request reprint Porcine VEG proteins and tear prealbumins
    M Garibotti
    Istituto di Industrie Agrarie, Pisa, Italy
    Chem Senses 20:69-76. 1995
    ..The two proteins appear to be identical, as in humans. The reason why the same protein is expressed in different tissues, as well as its physiological function, still remain to be clarified...
  29. ncbi request reprint Expression of odorant-binding proteins and chemosensory proteins in some Hymenoptera
    M Calvello
    Dipartimento di Chimica e Biotecnologie Agrarie, University of Pisa, Via S Michele, 4, 56124 Pisa, Italy
    Insect Biochem Mol Biol 35:297-307. 2005
    ..These data indicate that at least in some hymenopteran species CSPs are specifically expressed in antennae and could perform roles in chemosensory perception so far assigned only to OBPs...
  30. ncbi request reprint A rationale to design longer lasting mosquito repellents
    Immacolata Iovinella
    Department of Agriculture, Food and Environment, University of Pisa, 56124, Pisa, Italy
    Parasitol Res 113:1813-20. 2014
    ..The approach we illustrate can be applied to other compounds and other systems and offers the additional advantage that derivatives of reduced volatility are also endowed with weaker odours...
  31. doi request reprint Structure and biotechnological applications of odorant-binding proteins
    Paolo Pelosi
    Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto, 80, 56124, Pisa, Italy
    Appl Microbiol Biotechnol 98:61-70. 2014
    ....
  32. ncbi request reprint Multiple functions of an odorant-binding protein in the mosquito Aedes aegypti
    Sha Li
    Rothamsted NYNU Joint Laboratory, Nanyang Normal University, Nanyang, Henan, China Henan Normal University, Xinxiang, Henan, China
    Biochem Biophys Res Commun 372:464-8. 2008
    ..Antiserum against odorant-binding protein 22 also stained the edges and sensilla of spiracles, indicating a third, still unknown, role for this protein...
  33. ncbi request reprint Revisiting the odorant-binding protein LUSH of Drosophila melanogaster: evidence for odour recognition and discrimination
    Jing Jiang Zhou
    Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK
    FEBS Lett 558:23-6. 2004
    ....
  34. ncbi request reprint Solution structure of a chemosensory protein from the desert locust Schistocerca gregaria
    Simona Tomaselli
    Department of Chemistry, University of Naples Federico II, 80126 Napoli, Italy
    Biochemistry 45:10606-13. 2006
    ..In fact, incubation of the protein with a natural ligand, namely, oleamide, produced substantial changes to the NMR spectra, suggesting extensive conformational transitions upon ligand binding...
  35. pmc Cloning of an olfactory sensory neuron-specific protein in the land snail (Eobania vermiculata)
    Andrea Mazzatenta
    Dipartimento di Neurobiologia, Scuola Internazionale Superiore di Studi Avanzati, 34014 Trieste, Italy
    Proc Biol Sci 271:S46-9. 2004
    ..This protein could represent a plesiomorphic character in the evolution of olfactory proteins...
  36. ncbi request reprint Boar salivary lipocalin. Three-dimensional X-ray structure and androsterol/androstenone docking simulations
    Silvia Spinelli
    Architecture et Fonction des Macromolecules Biologiques, CNRS and Universités Aix Marseille I and II, France
    Eur J Biochem 269:2449-56. 2002
    ..This explains the higher affinity of SAL for both steroid molecules compared to other smaller molecules, although no specific interaction is established with either compound...