Research Topics
| Federica PellatiSummaryAffiliation: University of Modena and Reggio Emilia Country: Italy Publications
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Detail Information
Publications
Fast high-performance liquid chromatography analysis of phenethylamine alkaloids in Citrus natural products on a pentafluorophenylpropyl stationary phaseFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Chromatogr A 1165:58-66. 2007..65 to 27.41 mg/g. The other compounds were either not detected or were present at low levels. The developed method can be considered suitable for the quality control of Citrus plant material and commercial products...
Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia speciesFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Modena, Italy
J Sep Sci 29:641-9. 2006..The results of the application of the method to the analysis of Evodia samples showed that (-)-synephrine was the main component while (+)-synephrine was present in low concentration...
Chromatographic performance of a new polar poly(ethylene glycol) bonded phase for the phytochemical analysis of Hypericum perforatum LFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Chromatogr A 1088:205-17. 2005..The developed method could be considered suitable for the quality control of H. perforatum herb and derivatives...
Headspace solid-phase microextraction-gas chromatography--mass spectrometry analysis of the volatile compounds of Evodia species fruitsFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Chromatogr A 1087:265-73. 2005..13%) and alpha-terpineol (3.99%). As for E. officinalis, the major compounds were myrcene (32.79%), limonene (18.36%), beta-caryophyllene (9.92%), trans-beta-ocimene (6.04%), linalool (5.88%), beta-elemene (7.85%) and valencene (4.62%)...
High-performance liquid chromatography analysis of polyacetylenes and polyenes in Echinacea pallida by using a monolithic reversed-phase silica columnFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Modena, Italy
J Chromatogr A 1149:56-65. 2007..The validation procedure confirmed that this technique affords reliable analysis of these components and is appropriate for the quality control of complex matrices, such as E. pallida roots and phytopharmaceuticals...
Chromatographic and electrophoretic methods for the analysis of phenethylamine [corrected] alkaloids in Citrus aurantiumFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Chromatogr A 1161:71-88. 2007..The advantages and limitations of these separation and identification methods are assessed and discussed...
Isolation and structure elucidation of cytotoxic polyacetylenes and polyenes from Echinacea pallidaFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
Phytochemistry 67:1359-64. 2006..Results show that the hydroxylated compounds (1, 2) have low cytotoxicity, while the more hydrophobic polyacetylenes (3) and polyenes (4, 5) displayed moderate activity...
Simultaneous metabolite fingerprinting of hydrophilic and lipophilic compounds in Echinacea pallida by high-performance liquid chromatography with diode array and electrospray ionization-mass spectrometry detectionFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Modena, Italy
J Chromatogr A 1242:43-58. 2012..The developed method can be considered suitable for metabolite fingerprinting and quality control of E. pallida plant material and natural products...
Chromatographic methods for metabolite profiling of virus- and phytoplasma-infected plants of Echinacea purpureaFederica Pellati
Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Modena e Reggio Emilia, Via G Campi 183, 41125 Modena, Italy
J Agric Food Chem 59:10425-34. 2011..purpurea secondary metabolites, which is an important issue in defining the commercial quality, market value, and therapeutic efficacy of this herbal drug...
Determination of adrenergic agonists from extracts and herbal products of Citrus aurantium L. var. amara by LCFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via Campi 183, Modena, Italy
J Pharm Biomed Anal 29:1113-9. 2002..amara. Taking into account that some authors have reported that l-synephrine may be converted into its d-form by high temperature, this optical isomerization was monitored by the same HPLC method used for the separation of enantiomers...
High-performance liquid chromatography methods for the analysis of adrenergic amines and flavanones in Citrus aurantium L. var. amaraFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183. 411(00 Modena, Italy
Phytochem Anal 15:220-5. 2004..80 to 26.30 and from 3.90 to 14.71 mg/g, respectively. The levels of aglycones were very low in all samples tested...
Variability in the composition of anti-oxidant compounds in Echinacea species by HPLCFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via Campi 183, 41100 Modena, Italy
Phytochem Anal 16:77-85. 2005..The EC50 values of the samples ranged from 122 to 1223 microg/mL. The radical scavenging activities of the root extracts were correlated with the content of phenolic compounds, with a correlation coefficient (r2) of 0.923...
Enantioselective LC analysis of synephrine in natural products on a protein-based chiral stationary phaseFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Pharm Biomed Anal 37:839-49. 2005..aurantium samples showed that (-)-synephrine was the main component. (+)-Synephrine was not detected in C. aurantium fruits and was present in low concentration in the phytoproducts...
Study on the racemization of synephrine by off-column chiral high-performance liquid chromatographyFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Chromatogr A 1217:3503-10. 2010....
Isolation, structure elucidation and total synthesis of a cytotoxic dienone from Echinacea pallidaStefania Morandi
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100, Modena, Italy
Org Biomol Chem 6:4333-9. 2008..The results indicated that these compounds exert a dose-dependent cytotoxicity with a medium-level potency on the tested cell line...
Analysis of phenolic compounds and radical scavenging activity of Echinacea sppFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41100 Modena, Italy
J Pharm Biomed Anal 35:289-301. 2004..The results indicate that Echinacea roots and derivatives are a good source of natural antioxidants and could be used to prevent free-radical-induced deleterious effects...
Optimization and validation of a high-performance liquid chromatography method for the analysis of cardiac glycosides in Digitalis lanataFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Modena, Italy
J Chromatogr A 1216:3260-9. 2009..lanata plant material as source of cardiac glycosides, the developed method can be considered suitable for the phytochemical analysis and for the quality assurance of D. lanata used for pharmaceutical purpose...
Gas chromatography combined with mass spectrometry, flame ionization detection and elemental analyzer/isotope ratio mass spectrometry for characterizing and detecting the authenticity of commercial essential oils of Rosa damascena MillFederica Pellati
Department of Life Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41125 Modena, Italy
Rapid Commun Mass Spectrom 27:591-602. 2013..Due to its high value, it can be easily adulterated with flavors or cheaper oils. This study is aimed at a detailed phytochemical characterization of commercial samples of R. damascena essential oil and at their authenticity assessment...
Microparticulate polyelectrolyte complexes for gentamicin transport across intestinal epitheliaValentina Iannuccelli
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Italy
Drug Deliv 18:26-37. 2011..However, only the endocytosis by M cells appeared to provide the microparticle transport from the epithelium toward deeper sub-epithelial regions...
HPLC-DAD and HPLC-ESI-MS/MS methods for metabolite profiling of propolis extractsFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41125 Modena, Italy
J Pharm Biomed Anal 55:934-48. 2011..17 to 16.67mg/ml and the level of total flavonoids from 2.48 to 41.10mg/ml. The proposed method can be considered suitable for the phytochemical analysis of propolis extracts used in phytotherapy...
Determination of ephedrine alkaloids in Ephedra natural products using HPLC on a pentafluorophenylpropyl stationary phaseFederica Pellati
Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G Campi 183, 41100 Modena, Italy
J Pharm Biomed Anal 48:254-63. 2008....
PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acidLucia Bondioli
Department of Pharmaceutical Sciences, University of Modena and RE, Modena, Italy
Biomaterials 31:3395-403. 2010..Thus, the new Neu5Ac-modified PLGA polyester represent a useful starting material for the preparation of NPs surface decorated with this sialic acid...
P-Glycoprotein inhibitory activity of lipophilic constituents of Echinacea pallida roots in a human proximal tubular cell lineNadia Romiti
Department of Experimental Pathology, The School of Medicine, University of Pisa, Via Roma 55, Pisa, Italy
Planta Med 74:264-6. 2008..Pentadeca-(8 Z,13 Z)-dien-11-yn-2-one was the most efficient compound, being able to decrease the calcein-AM efflux about three-fold with respect to the control at 30 microg/mL...
Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infectionRenato Bruni
Dipartimento di Biologia Evolutiva e Funzionale, Sez Biologia Vegetale e Orto Botanico, Universita degli Studi di Parma, Parco Area delle Scienze 11A, 43100 Parma, Italy
J Agric Food Chem 53:964-8. 2005..The consequences that the phytopathological condition of cultivated H. perforatum plants has on the commercial quality, market value, and therapeutic efficacy are outlined...
