Francesco Patti

Summary

Affiliation: University of Catania
Country: Italy

Publications

  1. pmc Clinical efficacy issues in the treatment of multiple sclerosis: update of natalizumab
    Francesco Patti
    Multiple Sclerosis Center, University of Catania, Catania, Italy Physical Medicine and Rehabilitation Unit, Hospital of Acireale, Catania, Italy
    Clinicoecon Outcomes Res 1:45-51. 2009
  2. pmc Lights and shadows of cyclophosphamide in the treatment of multiple sclerosis
    Francesco Patti
    Department of Neuroscience, University of Catania, Catania, Italy
    Autoimmune Dis 2011:961702. 2011
  3. pmc Subcutaneous interferon β-1a may protect against cognitive impairment in patients with relapsing-remitting multiple sclerosis: 5-year follow-up of the COGIMUS study
    Francesco Patti
    Department of Neurology, Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital, Catania, Italy
    PLoS ONE 8:e74111. 2013
  4. pmc Optimizing the benefit of multiple sclerosis therapy: the importance of treatment adherence
    Francesco Patti
    Department of Neurology, University of Catania, Catania, Italy
    Patient Prefer Adherence 4:1-9. 2010
  5. doi request reprint Interferon-beta-1a treatment has a positive effect on quality of life of relapsing-remitting multiple sclerosis: results from a longitudinal study
    Francesco Patti
    Department DANA GF Ingrassia, Neurosciences Section, Multiple Sclerosis Centre, University of Catania, Catania, Italy Electronic address
    J Neurol Sci 337:180-5. 2014
  6. ncbi request reprint The pharmacokinetics of glatiramer acetate for multiple sclerosis treatment
    Silvia Messina
    Department G F Ingrassia, Section of Neurosciences, Universita degli Studi di Catania, Via S Sofia, 78, Catania, Italy 0953782642 0953782626
    Expert Opin Drug Metab Toxicol 9:1349-59. 2013
  7. doi request reprint Treatment of cognitive impairment in patients with multiple sclerosis
    Francesco Patti
    University Hospital Catania, Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, Neuroscience Section, GF Ingrassia Department, Via Santa Sofia 78, 95123 Catania, Italy
    Expert Opin Investig Drugs 21:1679-99. 2012
  8. doi request reprint Longitudinal changes in social functioning in mildly disabled patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: results from the COGIMUS (COGnitive Impairment in MUltiple Sclerosis) study (II)
    Francesco Patti
    Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital, and Department of Neurology, University of Catania, Catania, Italy
    Qual Life Res 21:1111-21. 2012
  9. pmc Changes in magnetic resonance imaging disease measures over 3 years in mildly disabled patients with relapsing-remitting multiple sclerosis receiving interferon β-1a in the COGnitive Impairment in MUltiple Sclerosis (COGIMUS) study
    Stefano Bastianello
    National Neurological Institute, C Mondino Foundation, Pavia, Italy
    BMC Neurol 11:125. 2011
  10. ncbi request reprint Effects of education level and employment status on HRQoL in early relapsing-remitting multiple sclerosis
    F Patti
    Department of Neurological Sciences, Multiple Sclerosis Centre, University of Catania, Italy
    Mult Scler 13:783-91. 2007

Detail Information

Publications69

  1. pmc Clinical efficacy issues in the treatment of multiple sclerosis: update of natalizumab
    Francesco Patti
    Multiple Sclerosis Center, University of Catania, Catania, Italy Physical Medicine and Rehabilitation Unit, Hospital of Acireale, Catania, Italy
    Clinicoecon Outcomes Res 1:45-51. 2009
    ..From the analyses of the six cases, it seems that the overall risk is around 1/1,000 and could increase with the number of NA infusions...
  2. pmc Lights and shadows of cyclophosphamide in the treatment of multiple sclerosis
    Francesco Patti
    Department of Neuroscience, University of Catania, Catania, Italy
    Autoimmune Dis 2011:961702. 2011
    ....
  3. pmc Subcutaneous interferon β-1a may protect against cognitive impairment in patients with relapsing-remitting multiple sclerosis: 5-year follow-up of the COGIMUS study
    Francesco Patti
    Department of Neurology, Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital, Catania, Italy
    PLoS ONE 8:e74111. 2013
    ..To assess the effects of subcutaneous (sc) interferon (IFN) -1a on cognition over 5 years in mildly disabled patients with relapsing-remitting multiple sclerosis (RRMS)...
  4. pmc Optimizing the benefit of multiple sclerosis therapy: the importance of treatment adherence
    Francesco Patti
    Department of Neurology, University of Catania, Catania, Italy
    Patient Prefer Adherence 4:1-9. 2010
    ..Future advances in the field of MS treatment will be explored, including the development of orally administered drugs, which may enhance adherence...
  5. doi request reprint Interferon-beta-1a treatment has a positive effect on quality of life of relapsing-remitting multiple sclerosis: results from a longitudinal study
    Francesco Patti
    Department DANA GF Ingrassia, Neurosciences Section, Multiple Sclerosis Centre, University of Catania, Catania, Italy Electronic address
    J Neurol Sci 337:180-5. 2014
    ..This multicenter, independent, observational and longitudinal study was aimed to evaluate the impact of different pharmaceutical formulations of IFNβ-1a on QoL in patients affected by relapsing-remitting multiple sclerosis (RRMS)...
  6. ncbi request reprint The pharmacokinetics of glatiramer acetate for multiple sclerosis treatment
    Silvia Messina
    Department G F Ingrassia, Section of Neurosciences, Universita degli Studi di Catania, Via S Sofia, 78, Catania, Italy 0953782642 0953782626
    Expert Opin Drug Metab Toxicol 9:1349-59. 2013
    ..Several in vitro studies on mice and human antigen-presenting cells (APCs) have shown that GA is able to bind to the major histocompatibility complex (MHC), on the surface of APCs, recognizing myelin basic protein (MBP)...
  7. doi request reprint Treatment of cognitive impairment in patients with multiple sclerosis
    Francesco Patti
    University Hospital Catania, Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, Neuroscience Section, GF Ingrassia Department, Via Santa Sofia 78, 95123 Catania, Italy
    Expert Opin Investig Drugs 21:1679-99. 2012
    ..Many treatments are available for MS, including disease-modifying drugs (DMDs) and symptomatic therapies, but what are their effects on cognitive performance?..
  8. doi request reprint Longitudinal changes in social functioning in mildly disabled patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: results from the COGIMUS (COGnitive Impairment in MUltiple Sclerosis) study (II)
    Francesco Patti
    Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital, and Department of Neurology, University of Catania, Catania, Italy
    Qual Life Res 21:1111-21. 2012
    ..To report longitudinal changes in and explore the influence of cognition on social functioning in mildly disabled patients with relapsing-remitting multiple sclerosis (RRMS)...
  9. pmc Changes in magnetic resonance imaging disease measures over 3 years in mildly disabled patients with relapsing-remitting multiple sclerosis receiving interferon β-1a in the COGnitive Impairment in MUltiple Sclerosis (COGIMUS) study
    Stefano Bastianello
    National Neurological Institute, C Mondino Foundation, Pavia, Italy
    BMC Neurol 11:125. 2011
    ..In clinical trials, MRI has been found to detect treatment effects with greater sensitivity than clinical measures; however, clinical and MRI outcomes tend to correlate poorly...
  10. ncbi request reprint Effects of education level and employment status on HRQoL in early relapsing-remitting multiple sclerosis
    F Patti
    Department of Neurological Sciences, Multiple Sclerosis Centre, University of Catania, Italy
    Mult Scler 13:783-91. 2007
    ..5; stable disease on enrollment; and no previous treatment with interferons, glatiramer acetate, or immunosuppressive drugs. Quality of life (QoL) was evaluated by the Multiple Sclerosis Quality of Life-54 questionnaire (MSQoL-54)...
  11. ncbi request reprint Predictors of quality of life among patients with multiple sclerosis: an Italian cross-sectional study
    Francesco Patti
    Policlinico Universitario, Clinica Neurologica, Catania, Italy
    J Neurol Sci 252:121-9. 2007
    ..The Italian FAMS questionnaire is a valid measure to assess the QoL concerns of patients with MS. FAMS is also easy to administer and is well accepted by patients...
  12. doi request reprint Treatment options of cognitive impairment in multiple sclerosis
    Francesco Patti
    Department of Neuroscience, Centre of Multiple Sclerosis, Catania, Italy
    Neurol Sci 31:S265-9. 2010
    ..Treatment strategies for cognitive impairment in MS are still in their infancy. This article will summarize several pharmacological attempts to enhance cognitive performances in people with MS...
  13. doi request reprint Effects of immunomodulatory treatment with subcutaneous interferon beta-1a on cognitive decline in mildly disabled patients with relapsing-remitting multiple sclerosis
    F Patti
    Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital Catania, Catania, Italy
    Mult Scler 16:68-77. 2010
    ..These findings suggest that sc IFNbeta-1a may have dose-dependent cognitive benefits in mildly disabled patients with RRMS, and may support early initiation of high-dose IFNbeta-1a treatment...
  14. doi request reprint Quality of life, depression and fatigue in mildly disabled patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon beta-1a: 3-year results from the COGIMUS (COGnitive Impairment in MUltiple Sclerosis) study
    F Patti
    Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital, Catania, Italy
    Mult Scler 17:991-1001. 2011
    ..The precise relationships among quality of life, depression, fatigue and cognitive impairment in multiple sclerosis (MS) are complex and poorly understood...
  15. doi request reprint Cognitive impairment in multiple sclerosis
    F Patti
    Department of Neurology, University of Catania, Catania, Italy
    Mult Scler 15:2-8. 2009
    ..Detailed studies of cognitive impairment in MS are rare and guidelines for the assessment of cognitive function in MS are lacking...
  16. ncbi request reprint Effects of interferon beta-1a and -1b over time: 6-year results of an observational head-to-head study
    F Patti
    Centro Sclerosi Multipla, Universita di Catania, Catania, Italy
    Acta Neurol Scand 113:241-7. 2006
    ..To evaluate and compare the long-term efficacy and safety of two different beta-interferon preparations (IFN-beta-1a vs IFN-beta-1b)...
  17. ncbi request reprint A double blind, placebo-controlled, phase II, add-on study of cyclophosphamide (CTX) for 24 months in patients affected by multiple sclerosis on a background therapy with interferon-beta study denomination: CYCLIN
    F Patti
    Dipartimento Scienze Neurologiche, Centro Sclerosi Multipla, Universita di Catania, Catania, Italy
    J Neurol Sci 223:69-71. 2004
    ..Vital signs and eventual adverse events will be collected monthly. The study will last 36 months, 12 for the enrollment phase and 24 for the treatment phase. The study will start on April 2004...
  18. pmc Subcutaneous Interferon Beta-1a Has a Positive Effect on Cognitive Performance in Mildly Disabled Patients with Relapsing-Remitting Multiple Sclerosis: 2-Year Results from the COGIMUS Study
    Francesco Patti
    Multiple Sclerosis Centre Sicilia Region, First Neurology Clinic, University Hospital Catania, Via Santa Sofia 78, 95123 Catania, Italy
    Ther Adv Neurol Disord 2:67-77. 2009
    ..94-22.64). These interim results show that IFN beta-1a sc tiw may have beneficial effects on cognitive function as early as 2 years after treatment initiation, but the final 3-year data of the study are required to confirm these results...
  19. doi request reprint Cognitive impairment and its relation with disease measures in mildly disabled patients with relapsing-remitting multiple sclerosis: baseline results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) study
    F Patti
    Department of Neurosciences, University of Catania, Catania, Italy
    Mult Scler 15:779-88. 2009
    ..Cognitive impairment is a common symptom of multiple sclerosis (MS), but the association between cognitive impairment and magnetic resonance imaging (MRI) disease measures in patients with relapsing-remitting (RR) MS is unclear...
  20. ncbi request reprint Caregiver quality of life in multiple sclerosis: a multicentre Italian study
    F Patti
    Department of Neurology, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy
    Mult Scler 13:412-9. 2007
    ..Therefore, caregiver QoL was significantly influenced by patient characteristics, and supportive strategies for MS caregivers are warranted...
  21. ncbi request reprint Health-related quality of life and depression in an Italian sample of multiple sclerosis patients
    Francesco Patti
    Dipartimento Neuroscienze, Sezione Sclerosi Multipla e Malattie Demielinizzanti, Azienda Policlinico Via Santa Sofia 78, 95123 Catania, Italy
    J Neurol Sci 211:55-62. 2003
    ..Depression strongly influenced the HRQoL of MS patients. EDSS and time since diagnosis also affected the HRQoL of MS patients. Our results are comparable with other European studies...
  22. pmc Epidural analgesia and cesarean delivery in multiple sclerosis post-partum relapses: the Italian cohort study
    Luisa Pastò
    Department of Neurology, University of Florence, Viale Morgagni 85, 50134, Florence, Italy
    BMC Neurol 12:165. 2012
    ..The objective of this study was to assess the impact of epidural analgesia (EA) and caesarean delivery (CD) on the risk of post-partum relapses and disability in women with MS...
  23. doi request reprint Increasing frequency of multiple sclerosis in Catania, Sicily: a 30-year survey
    Alessandra Nicoletti
    Department of Neurosciences, University of Catania, Catania, Italy
    Mult Scler 17:273-80. 2011
    ..The objective of this study was to determine the prevalence and incidence of multiple sclerosis (MS) and its temporal profiles from 1975 to 2005 in the city of Catania...
  24. ncbi request reprint Stabilization of rapidly worsening multiple sclerosis for 36 months in patients treated with interferon beta plus cyclophosphamide followed by interferon beta
    Francesco Patti
    Department of Neurological Sciences, Via Santa Sofia 78, 95123, Catania, Italy
    J Neurol 251:1502-6. 2004
    ..These encouraging findings and the absence of significant recorded side effects affirm that the association of CTX plus interferon-beta is amenable, safe and can be recommended in rapidly worsening MS patients...
  25. ncbi request reprint The combination of cyclophosphamide plus interferon beta as rescue therapy could be used to treat relapsing-remitting multiple sclerosis patients-- twenty-four months follow-up
    Ester Reggio
    Centre of Multiple Sclerosis and Degenerative Disease of the Nervous System, University of Catania, Via Conti 6, Italy
    J Neurol 252:1255-61. 2005
    ....
  26. ncbi request reprint Epilepsy and multiple sclerosis in Sicily: a population-based study
    Alessandra Nicoletti
    Department of Neuroscience, University of Catania, Catania, Italy
    Epilepsia 44:1445-8. 2003
    ..To evaluate the association between epilepsy and multiple sclerosis (MS), we analyzed the incidence of epilepsy in a population-based incidence cohort of MS in Catania, Sicily...
  27. ncbi request reprint A possible spatial and temporal cluster of multiple sclerosis in the town of Linguaglossa, Sicily
    Alessandra Nicoletti
    Dept of Neuroscience, University of Catania, Catania, Italy
    J Neurol 252:921-5. 2005
    ....
  28. pmc Multiple sclerosis and CCSVI: a population-based case control study
    Francesco Patti
    Department DANA GF Ingrassia, Section of Neurosciences, University of Catania, Catania, Italy
    PLoS ONE 7:e41227. 2012
    ..Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to multiple sclerosis (MS)...
  29. ncbi request reprint Effects of a short outpatient rehabilitation treatment on disability of multiple sclerosis patients--a randomised controlled trial
    Francesco Patti
    Institute of Neurological Sciences, University of Catania, Via Santa Sofia 78, 95125 Catania, Italy
    J Neurol 250:861-6. 2003
    ..This study demonstrates that a short outpatient rehabilitation treatment improves disability of MS patients, without changing their impairment and confirms the effectiveness of rehabilitation in people with MS...
  30. pmc Pregnancy and fetal outcomes after Glatiramer Acetate exposure in patients with multiple sclerosis: a prospective observational multicentric study
    Marta Giannini
    Department of Neurology, University of Florence, Florence, Italy
    BMC Neurol 12:124. 2012
    ....
  31. ncbi request reprint Psychometric properties of the Italian version of the Guy's Neurological Disability Scale
    Angelo Pappalardo
    Department of Neurological Sciences, University of Catania, Italy
    Funct Neurol 25:223-33. 2010
    ..77; p<0.001), in the RRMS patients (r=0.65, p<0.01), and in those with SPMS (r=0.48, p<0.05). In conclusion, the Italian version of the GNDS emerges as a valid assessment instrument with adequate basic psychometric properties...
  32. doi request reprint Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial
    G Comi
    Institute of Experimental Neurology, Department of Neurology, University Vita Salute, Scientific Institute San Raffaele, Milan, Italy
    Lancet 374:1503-11. 2009
    ..We assessed the efficacy of early treatment with glatiramer acetate in delaying onset of clinically definite multiple sclerosis...
  33. doi request reprint Headache and multiple sclerosis: a population-based case-control study in Catania, Sicily
    A Nicoletti
    Department of Neurosciences, University of Catania, Catania, Italy
    Cephalalgia 28:1163-9. 2008
    ..18 (95% confidence interval 1.27, 3.93). Frequency of headaches in our MS population is higher than in the general population, supporting the hypothesis of a possible association between these two conditions...
  34. ncbi request reprint The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian population
    M P Amato
    Department of Neurology, University of Florence, Viale Morgagni, 85 50134 Florence, Italy
    Mult Scler 12:787-93. 2006
    ..Increasing age was associated with worse performance on the ST in version A, and on the SRT-LTS, SRT-CLTR and WLG in version B. Our data can improve the applicability of the BRB for both clinical and research purposes...
  35. ncbi request reprint Brain atrophy and lesion load in a large population of patients with multiple sclerosis
    G Tedeschi
    Department of Neurological Sciences, Second University of Naples, Piazza Miraglia 2, 80138 Naples, Italy
    Neurology 65:280-5. 2005
    ..To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method...
  36. ncbi request reprint The impact of outpatient rehabilitation on quality of life in multiple sclerosis
    Francesco Patti
    Department of Neurological Sciences, Centro Sclerosi Multipla, Policlinico Universitario di Catania, Via Santa Sofia 78, 95123 Catania, Italy
    J Neurol 249:1027-33. 2002
    ..001). The results of this study confirm the effectiveness of a short comprehensive outpatient model of rehabilitative treatment in people with MS and in particular in their QoL...
  37. doi request reprint Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study
    G Tedeschi
    Department of Neurological Sciences, Second University of Naples, Naples, Italy
    Mult Scler 15:204-11. 2009
    ..To investigate in a large cohort of patients with multiple sclerosis (MS), lesion load and atrophy evolution, and the relationship between clinical and magnetic resonance imaging (MRI) correlates of disease progression...
  38. doi request reprint Cognitive and psychosocial features in childhood and juvenile MS: two-year follow-up
    M P Amato
    Department of Neurology, University of Florence, Viale Morgagni 85, Florence, Italy
    Neurology 75:1134-40. 2010
    ..To assess the evolution of cognitive and psychosocial functioning in a cohort of childhood and juvenile multiple sclerosis (MS) cases after a mean period of 2 years had elapsed since baseline evaluation...
  39. ncbi request reprint Treatment of multiple sclerosis with interferon beta in clinical practice: 2-year follow-up data from the South Italy Mobile MRI Project
    S Bonavita
    Department of Neurological Sciences, Second University of Naples, Piazza Miraglia 2, I 80138 Naples, Italy
    Neurol Sci 27:S365-8. 2006
    ..Despite some limitations in the trial design, the results from this follow-up study provide helpful clinical and MRI data on the efficacy of interferon beta regimens in MS patients treated in the clinical setting...
  40. ncbi request reprint Prevalence and incidence of multiple sclerosis in Catania, Sicily
    A Nicoletti
    Institute of Neurological Science, University of Catania, Italy
    Neurology 56:62-6. 2001
    ..An epidemiologic survey was conducted to determine the prevalence and incidence of MS in the city of Catania, Sicily, Italy. Prevalence rate was calculated as point prevalence at January 1,1995, and incidence during 1974 to 1995...
  41. pmc Multiple Sclerosis in the Mount Etna region: possible role of volcanogenic trace elements
    Alessandra Nicoletti
    Depatment G F Ingrassia Section of Neurosciences, University of Catania, Catania, Italy
    PLoS ONE 8:e74259. 2013
    ..Due to prevailing trade winds direction, volcanic gases from Etna summit craters are mostly blown towards the eastern and southern sectors of the volcano...
  42. ncbi request reprint Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability
    Gioacchino Tedeschi
    Department of Neurological Sciences, Second University of Naples, Naples, Italy
    J Neurol Sci 263:15-9. 2007
    ..Fatigue is a major problem in multiple sclerosis (MS), and its association with MRI features is debated...
  43. doi request reprint Pregnancy and fetal outcomes after interferon-β exposure in multiple sclerosis
    M P Amato
    Department of Neurology, University of Florence, Florence, Italy
    Neurology 75:1794-802. 2010
    ..To assess pregnancy and fetal outcomes after in utero exposure to interferon-β (IFNβ) in all pregnancies occurring in women with multiple sclerosis (MS) during the study period, with a specific focus on the risk of spontaneous abortion...
  44. doi request reprint Outcome of psychiatric symptoms presenting at onset of multiple sclerosis: a retrospective study
    Salvatore Lo Fermo
    Department of Neurosciences, University of Catania, Catania, Italy
    Mult Scler 16:742-8. 2010
    ..3), 14 subjects (87%) had a supplementary diagnosis of psychiatric illness. Psychiatric symptoms at onset of multiple sclerosis may be indicators of possible maintenance of psychiatric morbidity in a sizeable proportion of patients...
  45. doi request reprint Psychosocial issue in children and adolescents with multiple sclerosis
    B Goretti
    Department of Neurology, University of Florence, Florence, Italy
    Neurol Sci 31:467-70. 2010
    ..Our study confirms the critical role of psychosocial difficulties in children and adolescents with MS and provides a few cues to clinical management...
  46. ncbi request reprint Possible increasing risk of multiple sclerosis in Catania, Sicily
    A Nicoletti
    Department of Neurosciences, University of Catania, Catania, Italy
    Neurology 65:1259-63. 2005
    ..To update prevalence and incidence rates of multiple sclerosis (MS) in Catania, Italy during 1990 to 1999 and evaluate their temporal profiles to assess a possible increase in the MS risk in our study population...
  47. ncbi request reprint [Neurogenic dysphagia: physiology, physiopathology and rehabilitative treatment]
    F Patti
    Dipartimento di Scienze Neurologiche, Universita di Catania, Policlinico Via Santa Sofia 78, 95123 Catania
    Clin Ter 153:403-19. 2002
    ..Rehabilitation is aimed to make patient able for a safe oral feeding. We can use classic specific physiotherapy, compensatory movements of head and neck, electrostimulation, and the chemical myotomia by botulinum toxin injection...
  48. doi request reprint Cognitive and psychosocial features of childhood and juvenile MS
    M P Amato
    Department of Neurology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Neurology 70:1891-7. 2008
    ..To assess the impact of multiple sclerosis (MS) on cognitive and psychosocial functioning in childhood and juvenile cases...
  49. pmc Combination of cyclophosphamide and interferon-beta halts progression in patients with rapidly transitional multiple sclerosis
    F Patti
    Department of Neurological Sciences, University of Catania, Via S Sofia 78, 95123 Catania, Italy
    J Neurol Neurosurg Psychiatry 71:404-7. 2001
    ..The possibility is considered of carrying out further studies to test the efficacy of the association between the two drugs for patients who are not responsive to IFN-beta or other active disease modifying therapies...
  50. ncbi request reprint Impact of sociodemographic characteristics on cognitive performance in an elderly Sicilian population
    Giuseppe Salemi
    Department of Neurology, University of Palermo, Italy
    Neuroepidemiology 21:44-9. 2002
    ..To assess cognitive levels in an elderly Sicilian population and to evaluate the role of education and other sociodemographic characteristics in cognitive performance...
  51. doi request reprint Drug rash with eosinophilia and systemic signs syndrome in a patient with multiple sclerosis
    Angelo Caruso
    Department of Internal Medicine, University of Catania, Catania, Italy
    Clin Ther 31:580-4. 2009
    ..We describe a case of DRESS syndrome in a patient with multiple sclerosis (MS), characterized by a very high eosinophilia and cholestatic hepatitis...
  52. doi request reprint Sporadic motor neuron disease in a familial novel SOD1 mutation: incomplete penetrance or chance association?
    Francesca L Conforti
    Department of Neurosciences, University of Catania, Catania, Italy
    Amyotroph Lateral Scler 12:220-2. 2011
    ..The G61R mutation segregated in three unaffected relatives including the 80-year-old mother and two of the proband's siblings. Potential mechanisms include an autosomal dominant condition with reduced penetrance or a chance association...
  53. ncbi request reprint [Management of neuropathic bladder in multiple sclerosis]
    A Pappalardo
    Centro Sclerosi Multipla, Azienda Policlinico, Universita di Catania, Italia
    Clin Ter 155:183-6. 2004
    ..Therapy can usually eliminate or reduce the symptoms of neuropathic bladder. In the following pages is discussed the complex management of urinary symptoms in MS patients...
  54. ncbi request reprint The prevalence of pain in multiple sclerosis: a multicenter cross-sectional study
    C Solaro
    Department of Neurology, P A Micone Hospital, Genova, Italy
    Neurology 63:919-21. 2004
    ..This study underlines the relevance of pain in the clinical history of MS...
  55. doi request reprint The brief neuropsychological battery for children: a screening tool for cognitive impairment in childhood and juvenile multiple sclerosis
    E Portaccio
    Department of Neurology, University of Florence, Florence, Italy
    Mult Scler 15:620-6. 2009
    ....
  56. doi request reprint Is in utero early-exposure to interferon beta a risk factor for pregnancy outcomes in multiple sclerosis?
    F Patti
    Dept of Neurosciences, University of Catania, Via Santa Sofia 78, 95123, Catania, Italy
    J Neurol 255:1250-3. 2008
    ..Aim of this study is to evaluate risks of the administration of INFbeta related not only to the foetus, but also to children development up to 12-months developmental milestones...
  57. ncbi request reprint Validation of the DYMUS questionnaire for the assessment of dysphagia in multiple sclerosis
    Roberto Bergamaschi
    Multiple Sclerosis Centre, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 24:159-62. 2009
    ....
  58. doi request reprint Heme oxygenase-1 expression in peripheral blood mononuclear cells correlates with disease activity in multiple sclerosis
    Paolo Fagone
    Department of Bio Medical Sciences, University of Catania, Catania, Italy
    J Neuroimmunol 261:82-6. 2013
    ..We conclude that HO-1 may play a significant role in the maintenance of immune homeostasis which is disrupted in autoimmune disorders, such as MS...
  59. doi request reprint An exploration of anger phenomenology in multiple sclerosis
    U Nocentini
    Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy
    Eur J Neurol 16:1312-7. 2009
    ..Multiple sclerosis (MS) patients are often emotionally disturbed. We investigated anger in these patients in relation to demographic, clinical, and mood characteristics...
  60. doi request reprint The DYMUS questionnaire for the assessment of dysphagia in multiple sclerosis
    R Bergamaschi
    Multiple Sclerosis Centre, Neurological Institute C Mondino, Pavia, Italy
    J Neurol Sci 269:49-53. 2008
    ..It can be used for preliminary selection of patients to submit to more specific instrumental analyses, and to direct toward programs for prevention of aspiration...
  61. ncbi request reprint The antiinflammatory cytokine interleukin-13 is not detectable in the circulation of multiple sclerosis patients and is not inducible by interferon-beta1b treatment, that neither modifies its ex vivo secretion from peripheral blood mononuclear cells
    F Nicoletti
    Institute of Neurology, University of Catania, Italy
    Autoimmunity 32:265-70. 2000
    ....
  62. ncbi request reprint An MRI study of Chlamydia pneumoniae infection in Italian multiple sclerosis patients
    L M E Grimaldi
    Department of Neurosciences, AUSL 2 Caltanissetta, Via G Cusmano 3, 93100 Caltanissetta, Italy
    Mult Scler 9:467-71. 2003
    ..5 +/- 5 versus 4.4 +/- 4 years; P = 0.016) at the time of clinical evaluation. These findings, although indirectly, suggest that CP infection of the central nervous system (CNS) might affect disease course in a subgroup of MS patients...
  63. ncbi request reprint Osteoporotic vertebral compression fracture pain (back pain): our experience with balloon kyphoplasty
    A Guglielmino
    Anesthesia and Intensive Care Unit, University Polyclinic, Catania, Italy
    Minerva Anestesiol 73:77-100. 2007
    ....
  64. ncbi request reprint Botulinum toxin treatment of painful tonic spasms in multiple sclerosis
    D A Restivo
    Department of Neurology, Garibaldi Hospital, Catania, Italy
    Neurology 61:719-20. 2003
  65. ncbi request reprint [Spasticity in multiple sclerosis]
    A Pappalardo
    Centro Sclerosi Multipla, Universita di Catania, Italia
    Clin Ter 155:135-8. 2004
    ..In this article, the therapeutical management of MS spasticity, in all its components (pharmacological, rehabilitative, surgical) is reviewed...
  66. ncbi request reprint Frequency of celiac disease is not increased among multiple sclerosis patients
    A Nicoletti
    Dipartimento di Neuroscienze, Universita di Catania, Via Santa Sofia no 78, Catania, Italy
    Mult Scler 14:698-700. 2008
    ..Our data did not show an increased frequency of celiac disease among patients with MS...
  67. ncbi request reprint Sodium fusidate (fusidin) ameliorates the course of monophasic experimental allergic encephalomyelitis in the Lewis rat
    R Di Marco
    Department of Microbiological and Gynaecological Sciences, University of Catania, Catania, Italy
    Mult Scler 7:101-4. 2001
    ..These data provide further evidence for the anti-inflammatory effect of fusidin and suggest that this drug may be valuable for the treatment of human multiple sclerosis...
  68. ncbi request reprint Improvement of diabetic autonomic gustatory sweating by botulinum toxin type A
    D A Restivo
    Department of Physiological Sciences, University of Catania, Italy
    Neurology 59:1971-3. 2002
    ..This therapeutic approach, which could be used to reduce the severity of diabetic gustatory sweating, appears to be long lasting, adverse effect free, and minimally invasive...