Research Topics
Species | Giovanni PassalacquaSummaryAffiliation: University of Genoa Country: Italy Publications
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Publications
ARIA update: I--Systematic review of complementary and alternative medicine for rhinitis and asthmaGiovanni Passalacqua
Allergy and Respiratory Diseases, University of Genoa, Italy
J Allergy Clin Immunol 117:1054-62. 2006..There are also unresolved safety concerns. Therapeutic efficacy of complementary-alternative treatments for rhinitis and asthma is not supported by currently available evidence...- New insights in sublingual immunotherapyGiovanni Passalacqua
Allergy and Respiratory Diseases, DIMI, Padiglione Maragliano, L go R Benzi 10, 16132 Genoa Italy
Curr Allergy Asthma Rep 6:407-12. 2006..Additionally, the mechanisms of action are beginning to be systematically studied. Some points need further investigation, such as the effect in asthma, the mechanisms of action, and the optimal dose to be administered... - Sublingual immunotherapy: update 2006Giovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Curr Opin Allergy Clin Immunol 6:449-54. 2006..In the past 2 years, new data concerning clinical, immunological and practical aspects of sublingual immunotherapy have been published, and many critical points have been addressed... - Novel therapeutic interventions for allergic rhinitisGiovanni Passalacqua
University of Genoa, Padiglione Maragliano, Allergy and Respiratory Diseases, Department of Internal Medicine, Largo Rossana Benzi 10, Genoa, Italy
Expert Opin Investig Drugs 15:1615-25. 2006..Finally, one of the major goals is to modify the T(H)2-biased immune response by improving the characteristics and modes of action of allergen immunotherapy... - Complementary and alternative medicine for the treatment and diagnosis of asthma and allergic diseasesG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Monaldi Arch Chest Dis 63:47-54. 2005..Therefore these tests must not be used, since they can lead to delayed or incorrect diagnosis and therapy... 
Sublingual immunotherapy for allergic rhinitis and conjunctivitisGiovanni Passalacqua
Allergy and Respiratory Diseases, IRCCS San Martino IST University of Genoa, Padiglione Maragliano, L go R Benzi 10, 16132 Genoa, Italy
Immunotherapy 5:257-64. 2013..Only six anaphylaxes and no fatalities have been so far reported. Due to the good risk:benefit ratio, SLIT is currently being investigated in diseases other than respiratory allergy, such as food allergy and atopic dermatitis...- Adherence to pharmacological treatment and specific immunotherapy in allergic rhinitisG Passalacqua
Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy
Clin Exp Allergy 43:22-8. 2013..In this article, the literature concerning the adherence to pharmacological treatments and immunotherapy in allergic rhinitis was searched and reviewed... - Emerging drugs for perennial allergic rhinitisGiovanni Passalacqua
Allergy and Respiratory Diseases, IRCCS S Martino IST University of Genoa, Padiglione Maragliano, L go R Benzi 10, 16132 Genoa, Italy
Expert Opin Emerg Drugs 17:543-53. 2012..Some more promising advances have been shown for allergen immunotherapy, where a number of new strategies are currently under development... 
Diagnostic tools in Rhinology EAACI position paperGlenis Scadding
Royal National Throat, Nose and Ear Institute, London, UK
Clin Transl Allergy 1:2. 2011..A panel of European experts in the field of Rhinology has contributed to this consensus document on Diagnostic Tools in Rhinology...- Oral immunotherapy for cow's milk allergyGiovanni Passalacqua
Allergy and Respiratory Diseases, DIMI, University of Genoa, Italy
Curr Opin Allergy Clin Immunol 12:271-7. 2012..As no pharmacological treatment is available, specific desensitization has been considered an attractive strategy... - Lack of neo-sensitization to Pen a 1 in patients treated with mite sublingual immunotherapyRenato E Rossi
Allergy Unit, National Health Service, Rete di Allergologia Regione Piemonte, Cuneo 1, Italy
Clin Mol Allergy 8:4. 2010..Some studies reported the possible induction of food allergy, caused by neo-sensitization to cross-reacting allergens, during immunotherapy with aeroallergens, while other studies ruled out such possibility... - Euro coins and contact dermatitisC Lombardi
Allergy and Respiratory Diseases, Department of Internal Medicine, Pad. Maragliano, Largo R. Benzi 10, 16132 Genoa, Italy
Allergy 59:669-70. 2004 - An update on the asthma-rhinitis linkGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa University, Italy
Curr Opin Allergy Clin Immunol 4:177-83. 2004..For the present article we collected and reviewed the more relevant experimental results concerning the asthma-rhinitis link in allergic diseases, published since January 2002... - Sublingual immunotherapy: an updateGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Curr Opin Allergy Clin Immunol 4:31-6. 2004..Recently published studies have provided answers to some of these points... - A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitisGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Clin Ther 27:979-92. 2005..Levocetirizine and desloratadine are newer antihistamines indicated for the treatment of allergic rhinitis and chronic idiopathic urticaria... - Allergic and non-allergic rhinitis in swimmers: clinical and cytological aspectsMatteo Gelardi
Department of Otolaryngology II, University of Bari, Bari, Italy
Br J Sports Med 46:54-8. 2012..The aim of this study was to detail the clinical and cytological characteristics of rhinitis in swimmers, and to assess the possible role of chlorine-induced symptoms... - Investigational drugs for allergic rhinitisGiovanni Passalacqua
University of Genoa, Allergy and Respiratory Diseases, Department of Internal Medicine, Padiglione Maragliano, 16132 Genoa, Italy
Expert Opin Investig Drugs 19:93-103. 2010..Thus, an intense research activity is presently ongoing with the aim of improving the characteristics and modes of action of this treatment... - Allergy and the lungG Passalacqua
Allergy and Respiratory Diseases, Department of Internatl Medicine, San Martino Hospital, Padigliano Maragliano, Italy
Clin Exp Immunol 153:12-6. 2008..The recent introduction of biological treatments (monoclonal antibodies) has allowed elucidation of some of the pathogenic features of allergic asthma... - Comparison of the effects in the nose and skin of a single dose of desloratadine and levocetirizine over 24 hoursGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Int Arch Allergy Immunol 135:143-7. 2004..We compared the effects of a single dose of the two drugs in the nose and skin over 24 h... - Advances in allergen-specific immunotherapyGiovanni Passalacqua
DIMI, University of Genoa, Italy
Curr Drug Targets 10:1255-62. 2009..The last frontier seems to be the manipulation of genoma with replicons and allergen-encoding plasmids... - Allergic rhinitis in womenGiovanni Passalacqua
University of Genoa, Allergy and Respiratory Diseases, Department of Internal Medicine, PadiglioneMaragliano, L go R Benzi 10, 16132, Genoa, Italy
Womens Health (Lond Engl) 3:603-11. 2007..This review will examine the aforementioned aspects, with particular regard to the pharmacotherapy of rhinitis in pregnancy... - Sublingual immunotherapyGiovanni Passalacqua
Department of Internal Medicine, University of Genoa, Italy
Rev Alerg Mex 50:220-5. 2003..This paper reviews the up-to-date aspects about clinical efficacy, safety and pharmacokinetics of sublingual immunotherapy... - Latex-jujube cross-reactivity: case report and immunological studyC Lombardi
Allergy and Respiratory Diseases, Department of Internal Medicine Padiglione Maragliano, L.go R. Benzi 10, 16132 Genoa, Italy
Allergy 60:971-2. 2005 - Pharmacokinetics of radiolabelled Par j 1 administered intranasally to allergic and healthy subjectsG Passalacqua
Allergy and Respiratory Diseases, University of Genoa, Genoa, Italy
Clin Exp Allergy 35:880-3. 2005..Local nasal immunotherapy is accepted as an alternative to the injection route for allergic rhinitis. Despite this, little is known about the kinetics of the allergen after nasal delivery in allergic subjects... - Specific immunotherapy in asthma: efficacy and safetyG Passalacqua
Allergy and Respiratory Diseases, University of Genoa, Genoa, Italy
Clin Exp Allergy 41:1247-55. 2011..In such case, a measurable clinical benefit on asthma symptoms can be expected. On the other hand, SIT cannot be presently recommended as single therapy when asthma is the unique manifestation of respiratory allergy... - Rhinitis, rhinosinusitis and quality of life in childrenG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Pediatr Allergy Immunol 18:40-5. 2007..It has become clear that the QoL questionnaires measure the aspects of the disease that partially differ from the routinely evaluated parameters and that QoL should integrate, not replace, the objective measurements... - Efficacy and safety of sublingual immunotherapyGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Ann Allergy Asthma Immunol 93:3-12; quiz 12-3, 103. 2004.... - Specific immunotherapy: beyond the clinical scoresGiovanni Passalacqua
Allergy and Respiratory Diseases, University of Genoa, Italy
Ann Allergy Asthma Immunol 107:401-6. 2011..The literature is reviewed to evaluate the available experimental data on this... - Non-injection routes for allergen immunotherapy: focus on sublingual immunotherapyGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Inflamm Allergy Drug Targets 5:43-51. 2006..Several points still need to be elucidated, including: mechanisms of action, optimal dosages, and indications in pediatric patients... - Quantitative assessment of the compliance with once-daily sublingual immunotherapy in children (EASY project: evaluation of a novel SLIT formulation during a year)Giovanni Passalacqua
Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy
Pediatr Allergy Immunol 18:58-62. 2007..4%) for side effects probably related to therapy. These data obtained in a quite large sample of children and in real-life confirm that the compliance with SLITOne is good, despite the therapy managed at home... - Sublingual immunotherapy for allergic respiratory diseases: efficacy and safetyGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Padiglione Maragliano, Largo Rosanna Benzio 10, 16132 Genoa, Italy
Immunol Allergy Clin North Am 31:265-77, ix. 2011..The sublingual route (SLIT) seemed to be a good candidate for the clinical practice because of its satisfactory safety profile and is now considered an acceptable alternative to SCIT in adults and children... - Allergic rhinitis and its impact on asthma update: allergen immunotherapyGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
J Allergy Clin Immunol 119:881-91. 2007..Novel approaches for immunotherapy are currently under evaluation, including the use of adjuvants, peptides, and DNA-conjugated and recombinant allergens... - Sublingual immunotherapy for allergic rhinitis: an updateGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Curr Opin Otolaryngol Head Neck Surg 19:43-7. 2011..We will review herein a brief history of SLIT, its indications and the safety aspects and will discuss the main unmet needs and the points to be developed in the field... - Levocetirizine in persistent allergic rhinitis: continuous or on-demand use? A pilot studyGiorgio Walter Canonica
University of Genoa, Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa, Italy
Curr Med Res Opin 24:2829-39. 2008..According to the ARIA initiative, it is classified as intermittent and persistent, the latter being the most troublesome... - The possible influence of the environment on respiratory allergy: a survey on immigrants to ItalyCarlo Lombardi
Allergy Unit, Department of Internal Medicine, Sant Orsola Hospital, Brescia, Italy
Ann Allergy Asthma Immunol 106:407-11. 2011..Respiratory allergy is influenced and determined by genetic and environmental factors. Migration is a good model to indirectly evaluate the possible influence of environment... - Randomized open comparison of the safety of SLIT in a no-updosing and traditional updosing schedule in patients with Parietaria allergyLaura Guerra
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Allergol Immunopathol (Madr) 34:82-3. 2006.... - Pharmacokinetics of Der p 2 allergen and derived monomeric allergoid in allergic volunteersMarcello Bagnasco
Medical and Radiometabolic Therapy, University of Genoa, Genoa, Italy
Int Arch Allergy Immunol 138:197-202. 2005..The contribution of enteric absorption of the allergoid in the mechanism of action of sublingual immunotherapy remains to be defined... - Specific immunotherapy for respiratory allergy: state of the art according to current meta-analysesEnrico Compalati
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Ann Allergy Asthma Immunol 102:22-8. 2009..To evaluate the efficacy of allergen specific immunotherapy in the treatment of allergic asthma and rhinitis as derived by the available meta-analyses... - Sublingual and oral immunotherapyGiorgio Walter Canonica
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Padiglione Maragliano, L go R Benzi 10, Genoa 16132, Italy
Immunol Allergy Clin North Am 24:685-704, vii. 2004..The indications for SLIT are similar to those for the subcutaneous route. A long-lasting effect has been demonstrated for the sublingual route, but data are needed to determine the optimal dose and the preventive effect in asthma... - Clinical and therapeutic aspects of allergic asthma in adolescentsCarlo Lombardi
Allergy and Respiratory Unit, Department of Internal Medicine, S. Orsola Hospital, Brescia, Italy
Pediatr Allergy Immunol 14:453-7. 2003..From a clinical and functional point of view, asthma in adolescents did not differ from other age ranges. Nevertheless, the management (diagnosis and therapy) emerged to be unsatisfactory from many points of view... - The clinical characteristics of respiratory allergy in immigrants in northern ItalyCarlo Lombardi
Allergy Unit, Department of Internal Medicine, Sant Orsola Hospital, Brescia, Italy
Int Arch Allergy Immunol 147:231-4. 2008..Migration is a good epidemiological model to indirectly assess the influence of the environment. We assessed the clinical characteristics of respiratory allergy in immigrants in Brescia, Italy... - Metaanalysis of the efficacy of sublingual immunotherapy in the treatment of allergic asthma in pediatric patients, 3 to 18 years of ageMartin Penagos
Division of Allergy and Respiratory Diseases, Department of Internal, edicine, University of Genoa, Genoa, Italy
Chest 133:599-609. 2008..We evaluated the efficacy of SLIT in the treatment of allergic asthma in children by a metaanalysis of randomized, double-blind, and placebo-controlled (DBPC) clinical trials... - Role of contact sensitization in chronic urticariaLaura Guerra
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
J Am Acad Dermatol 56:88-90. 2007..In all patients, avoidance measures led to a complete remission within 1 month. We suggest that testing for contact sensitization can be helpful in the management of chronic urticaria... - Safety of allergen-specific sublingual immunotherapy and nasal immunotherapyGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa University, Genoa, Italy
Chem Immunol Allergy 82:109-18. 2003..Its safety is also supported by pharmacokinetics and immunological data. Experimental data on the safety of sublingual and nasal immunotherapy will be reviewed... - Efficacy of sublingual immunotherapy in the treatment of allergic rhinitis in pediatric patients 3 to 18 years of age: a meta-analysis of randomized, placebo-controlled, double-blind trialsMartin Penagos
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Ann Allergy Asthma Immunol 97:141-8. 2006..CONCLUSION: The results of this meta-analysis showed that,compared with placebo, SLIT with standardized extracts is effective in pediatric patients with allergic rhinitis... - Evidences of efficacy of allergen immunotherapy in atopic dermatitis: an updated reviewEnrico Compalati
Allergy and Respiratory Diseases Clinic, Department of Internal Medicine, University of Genoa, Genova, Italy
Curr Opin Allergy Clin Immunol 12:427-33. 2012..To update and assess the quality of the evidence concerning the efficacy of allergen immunotherapy for atopic eczema. Desensitization for eczema as a clinical manifestation of food allergy was not a target of this review... - Nasal eosinophils display the best correlation with symptoms, pulmonary function and inflammation in allergic rhinitisGiorgio Ciprandi
Head-Neck Department, S. Martino Hospital, Genoa, Italy
Int Arch Allergy Immunol 136:266-72. 2005..CONCLUSION: Eosinophils in the nasal smear display the best correlation with all the clinical and immunological parameters in allergic rhinitis and also correlate well with methacholine response... - Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion moleculesGiorgio Ciprandi
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
J Allergy Clin Immunol 112:S78-82. 2003.... - The safety of allergen specific sublingual immunotherapyGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Curr Drug Saf 2:117-23. 2007..Finally, it seems that the occurrence of some adverse events, at variance with injection route, does not depend strictly on the dose of allergen administered... - Allergy and the noseG Ciprandi
Semeiotica e Metodologia Medica I, Department of Internal Medicine, University of Genoa, Genoa, Italy
Clin Exp Immunol 153:22-6. 2008..Therefore, the management of AR patients should be rigorously careful and multi-disciplinary... - The IgE repertoire in children and adolescents resolved at component level: a cross-sectional studyGiovanni Melioli
UOC Laboratorio Centrale di Analisi, Istituto Giannina Gaslini, Genoa, Italy
Pediatr Allergy Immunol 23:433-40. 2012..However, little information is available on the evolution of the IgE repertoire directed to single allergenic components. In this cross-sectional, observational study, the evolution of the IgE repertoire was analysed at component level... - Effects of different up-dosing regimens for hymenoptera venom immunotherapy on serum CTLA-4 and IL-10Anna Maria Riccio
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
PLoS ONE 7:e37980. 2012..It has been shown that the circulating form of CTLA-4 is elevated in patients with hymenoptera allergy and can be down regulated by immunotherapy... - The functional connection between oral allergy syndrome and united airways disease assessed by oral challengeCarlo Lombardi
Allergy Unit, Department of Internal Medicine, Sant Orsola Hospital, Brescia, Italy
Ann Allergy Asthma Immunol 108:30-3. 2012..The airways and the upper digestive tract have a common embryonic origin. In sensitized subjects they can respond to allergens with an immediate reaction (asthma, rhinitis, or oral allergy syndrome [OAS])... - Allergen biodistribution in humansMarcello Bagnasco
Allergy and Clinical Immunology Unit, Department of Internal Medicine, Genoa University, Genoa, Italy
Chem Immunol Allergy 82:33-43. 2003..These data are potentially useful to improve immunotherapy treatment protocols by noninjectable routes... - Impact of bariatric surgery on pulmonary function and nitric oxide in asthmatic and non-asthmatic obese patientsCarlo Lombardi
Allergy Unit, Department of Internal Medicine, Sant Orsola Poliambulanza Hospital, Brescia, Italy
J Asthma 48:553-7. 2011..Asthma is an important co-morbidity of obesity. This study evaluated the impact of bariatric surgery on respiratory function in obese patients and compared the outcomes in asthmatic and non-asthmatic subjects... - Noninjection routes for immunotherapyGiorgio Walter Canonica
Division of Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
J Allergy Clin Immunol 111:437-48; quiz 449. 2003..Although the long-lasting efficacy has been recently documented for the sublingual route, several points still need to be elucidated, including mechanisms of action, optimal dosage, cost-effectiveness, and adherence... - Emerging sublingual immunotherapy drugsEnrico Compalati
University of Genoa, Allergy and Respiratory Diseases Clinic, Department of Internal Medicine, Italy
Expert Opin Pharmacother 11:2963-72. 2010..Sublingual immunotherapy (SLIT) has gained increasing interest for its efficacy comparable to traditional subcutaneous immunotherapy and its good safety profile... - Oral and sublingual immunotherapy in paediatric patientsGiovanni Passalacqua
Department of Internal Medicine, University of Genoa, Italy
Curr Opin Allergy Clin Immunol 3:139-45. 2003..Some aspects, such as the dose-response relationship and preventive effect, will be a research challenge for future developments and better definition of indications in children... - Levocetirizine in persistent allergic rhinitis and asthma: effects on symptoms, quality of life and inflammatory parametersM Pasquali
Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy
Clin Exp Allergy 36:1161-7. 2006..In the active group, only two patients used rescue medications compared with 13 patients in the placebo group. Conclusions LCZ is clinically effective and capable of improving the rhinitis-asthma-related QoL... - Clinical and cytologic characteristics of allergic rhinitis in elderly patientsMaria Teresa Ventura
Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari, Bari, Italy
Ann Allergy Asthma Immunol 108:141-4. 2012..Thus, special attention to allergic diseases in elderly people has begun to emerge, but little is known about the effect and features of allergic rhinitis in elderly people... - Targeted therapy for allergic asthma: predicting and evaluating response to omalizumabFrancesco Tarantini
Pulmunologist, PhD Student, DIMI University of Genoa, Allergy and Respiratory Diseases, Padiglione Maragliano, Largo R Benzi, 16132 Genova, Italy
Expert Rev Clin Immunol 3:463-7. 2007..The results established that it is difficult to predict which patients will gain most benefit from treatment, according to pretreatment baseline characteristics... - Sublingual immunotherapy: other indicationsGiovanni Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Padiglione Maragliano, Largo R Benzi 10, Genoa 16132, Italy
Immunol Allergy Clin North Am 31:279-87, ix. 2011..In hymenoptera allergy, the only trial available is a proof-of-concept study in large local reactions that needs to be confirmed in well-controlled studies... - Emerging anti-inflammatory agents for allergic rhinitisGiorgio Ciprandi
Dipartimento Patologie Testa Collo, Azienda Ospedaliera Universitaria San Martino, Allergologia U O ORL, Largo R Benzi 10, 16132 Genoa, Italy
Expert Opin Emerg Drugs 10:689-705. 2005..Finally, one of the major goals is to modify the TH2-biased immune response by improving the characteristics and modes of action of allergen immunotherapy... - Single-dose oral tolerance test with alternative compounds for the management of adverse reactions to drugsGiovanni Passalacqua
Allergy and Respiratory Diseases, DIMI, Department of Internal Medicine, Genoa University, Italy
Int Arch Allergy Immunol 129:242-7. 2002..Adverse reactions to drugs are common in the clinical practice. Many outpatients are frequently referred to allergists in order to determine which drugs they can safely take in the future... - The safety of sublingual immunotherapy with one or more allergens in adultsC Lombardi
Allergy and Respiratory Diseases, Department of Internal Medicine, Padiglione Maragliano, L.go R. Benzi 10, 16132 Genoa, Italy
Allergy 63:375-6. 2008 - Long-term cetirizine treatment reduces allergic symptoms and drug prescriptions in children with mite allergyG Ciprandi
Allergy and Immunology Clinic, Genoa, Italy
Ann Allergy Asthma Immunol 87:222-6. 2001..This suggests that long-term continuous treatment be included in the global strategy of allergy treatment... - Underdiagnosis and undertreatment of asthma: a 9-year study of Italian conscriptsG Ciprandi
Allergy and Respiratory Diseases, DIMI, University of Genoa, Italy
Int Arch Allergy Immunol 125:211-5. 2001..During the last 20 years, the epidemiology of asthma has been investigated in various populations, thus providing interesting data including the accuracy of diagnosis and the adequacy of treatment... - Intranasal mometasone furoate reduces late-phase inflammation after allergen challengeG Ciprandi
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Ann Allergy Asthma Immunol 86:433-8. 2001..Topical corticosteroids have been accepted as a highly effective anti-inflammatory therapy for allergic rhinitis... - Efficacy of mometasone furoate nasal spray in the treatment of allergic rhinitis. Meta-analysis of randomized, double-blind, placebo-controlled, clinical trialsM Penagos
Allergy and Respiratory Diseases Clinic, Department of Internal Medicine, Universita degli Studi di Genova, Genoa, Italy
Allergy 63:1280-91. 2008.... - Asthma treatment: 'magic bullets which seek their own targets'F Tarantini
Allergy and Respiratory Diseases, DIMI University of Genoa, Genova, Italy
Allergy 62:605-10. 2007..In fact, it proved to reduce exacerbations and symptom scores, and to improve quality of life, with a very good safety profile... - Role of leukotriene receptor antagonists in the management of mild-to-moderate asthmaM Milanese
Department of Internal Medicine, University of Genoa, Italy
Monaldi Arch Chest Dis 56:508-13. 2001..For this reason, even if ICS are superior to LTRAs in controlling asthma outcomes and in improving pulmonary function, in children and elderly patients LTRAs can be considered an alternative to low-dose ICS... - 100 Years of Immunotherapy: The Monaco Charter. Under the High Patronage of His Serene Highness Prince Albert II of MonacoG Walter Canonica
Allergy and Respiratory Disease Clinic, University of Genoa, IRCCS AOU San Martino IST, Genoa, Italy
Int Arch Allergy Immunol 160:346-9. 2013.... - Sublingual Immunotherapy: Clinical Indications in the WAO-SLIT Position PaperGiovanni Passalacqua
From Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy
World Allergy Organ J 3:216-9. 2010..Atopic dermatitis, latex allergy, and hymenoptera hypersensitivity are promising fields of use of SLIT, but they are still considered only experimental uses... - The asthma-rhinitis association: between the clinical hypothesis and the scientific theoryGiovanni Passalacqua
Allergy and Respiratory Diseases--Department of Internal Medicine, University of Genoa, Padiglione Maragliano, Largo R. Benzi, 10, 16132 Genoa, Italy
Curr Allergy Asthma Rep 3:191-3. 2003 - Effects on symptoms and quality of life of hypertonic saline nasal spray added to antihistamine in persistent allergic rhinitis--a randomized controlled studyA Rogkakou
Allergy and Respiratory Diseases, DIMI, University of Genoa
Eur Ann Allergy Clin Immunol 37:353-6. 2005 - The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: results of a GA2LEN meta-analysisE Compalati
Allergy and Respiratory Disease Clinic, Department of Internal Medicine, University of Genoa, Genoa, Italy
Allergy 64:1570-9. 2009..These findings suggest that more data are needed, derived from large-population-based high quality studies, and corroborated by objective outcomes, mainly for AA... - Is sublingual immunotherapy the final answer? Implications for the allergistGiorgio Walter Canonica
From the Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy This work has been partially supported by the Associazione Ricerca Malattie Immunologiche e Allergiche
World Allergy Organ J 1:70-2. 2008..Nonetheless, as happens with injection immunotherapy, it is mandatory that the prescription of SLIT is made by a trained specialist, and that a detailed diagnosis is made before prescribing it... - Aerobiologic diagnosis of brassicaceae-induced asthmaA Fiorina
Allergy and Respiratory Diseases, Department of Internal Medicine, Pad.Maragliano, L.go R.Benzi 10, 16132 Genoa, Italy
Allergy 58:829-30. 2003 - Looking for immunotolerance: a case of allergy to baker's yeast (Saccharomyces cerevisiae)G B Pajno
Allergy and Respiratory Diseases, DIMI, University of Genoa, Italy
Allerg Immunol (Paris) 37:271-2. 2005..We speculate that the continuous exposure to saccharomyces in foods may have lead to an immunotolerance with a progressive reduction of symptoms, whereas why the allergens is active only in ready-baked foods remains unexplained... - Continuing medical education. The point of view of asthmatic patients at the beginning of a mandatory CME systemF Braido
Allergy and Respiratory Diseases, DIMI, Genoa University, Genoa, Italy
J Investig Allergol Clin Immunol 14:274-7. 2004.... - Sublingual immunotherapy in the treatment of adult allergic rhinitis patientsG W Canonica
Allergy and Respiratory Diseases, DIMI, University of Genoa, Padiglione Maragliano, Genoa, Italy
Allergy 61:20-3. 2006..Key priorities for further investigation are the mechanisms of action, the efficacy in asthma, the cost/effectiveness and the identification of those patients who will achieve the maximum benefit with SLIT... - Rhinasthma: a new specific QoL questionnaire for patients with rhinitis and asthmaI Baiardini
Allergy and Respiratory Diseases, DIMI, Genoa University, Genoa, Italy
Allergy 58:289-94. 2003..It provides a short and simple assessment, and has overall psychometric properties. This is of relevance because of the frequent asthma-rhinitis comorbidity... - Localized eosinophilic ileitis with mastocytosis successfully treated with oral budesonideC Lombardi
Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa, Italy
Allergy 62:1343-5. 2007 - Randomized double-blind controlled study with sublingual carbamylated allergoid immunotherapy in mild rhinitis due to mitesG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy
Allergy 61:849-54. 2006..The need for extra visits was significantly lower in the active group (25%vs 43%). CONCLUSIONS: Sublingual immunotherapy was clinically effective and safe in mite-induced mild disease... - Oral and sublingual immunotherapy: general aspects and critical considerationsG Passalacqua
Department of Allergy and Respiratory Diseases, Genoa University, Italy
Wien Med Wochenschr 149:433-7. 1999..Furthermore, SLIT reduces time and money expenses usually required by SIT since it is self-administered... - Impact of rhinitis on airway inflammation: biological and therapeutic implicationsG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Respir Res 2:320-3. 2001..We discuss some of the recent observations on the nose-lung interaction and some of the novel therapeutic approaches used to treat rhinitis and asthma that arise from this... - The nose-lung interaction in allergic rhinitis and asthma: united airways diseaseG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa University, Italy
Curr Opin Allergy Clin Immunol 1:7-13. 2001..In this article, therefore, we collected and reviewed the most relevant experimental results available to support the hypothesis for united airways disease and the studies conducted on the possible mechanisms of nose-lung interaction... - Economic evaluation of sublingual immunotherapy: an analysis of literatureG Ciprandi
Dipartimento di malattie immuno allergologiche, Semeiotica Medica I, Ospedale Universitario S Martino, Genoa, Italy
Eur Ann Allergy Clin Immunol 39:21-6. 2007..The data obtained, although the number of studies is still limited, provide preliminary evidence supporting a SLIT effect on sparing costs for respiratory allergy... - Severe respiratory allergy induced by indirect exposure to rabbit dander: a case reportG Liccardi
Allergy and Respiratory Diseases, Department of Internal Medicine, Pad. Maragliano, L.go R.Benzi 10 16132, Genoa, Italy
Allergy 59:1237-8. 2004 - Aerobiological diagnosis of respiratory allergy by a personal sampler: two case reportsA Fiorina
DIMI, University of Genoa, Italy
J Investig Allergol Clin Immunol 13:284-5. 2003..We suggest that, in selected cases of difficult diagnosis the presence of proximity allergens is suspected, aerobiological sampling with a portable device should be considered... - Treating the allergic patient: think globally, treat globallyG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Allergy 57:876-83. 2002 - Melkersson-Rosenthal syndrome associated with parvovirus B19 viraemia and haemophagocytic lymphohistiocytosisA De Maria
Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy
Clin Exp Dermatol 34:e623-5. 2009..This observation suggests a possible association between PB19 and HL, and opens the possibility of its association also with acute-onset MRS. Further investigations for the presence of PB19 in cases of MRS are warranted... - Allergen-specific sublingual immunotherapy for respiratory allergyG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa University, Genoa, Italy
BioDrugs 15:509-19. 2001..It is intended to be used in association with proper pharmacological treatment, at the earliest stages of the disease, for optimal management of respiratory allergy... - Seasonal and perennial allergic rhinitis: is this classification adherent to real life?G Ciprandi
Head Neck Department, S Martino Hospital, Genoa, Italy
Allergy 60:882-7. 2005..We assessed the validity of the traditional classification in a large group of subjects suffering from allergic rhinitis alone... - Allergic rhinitis in the Italian population evaluated through the national database of general practitionersL G Mantovani
Allergy and Respiratory Diseases, Department of Internal Medicine Padiglione Maragliano, L.go R. Benzi 10, 16132 Genoa, Italy
Allergy 62:569-71. 2007 - Correlation among FEV, nitric oxide and asthma control test in newly diagnosed asthmaG Senna
Allergy and Respiratory Diseases, Department of Internal Medicine, Padiglione Maragliano, L go R Benzi 10 16132, Genoa, Italy
Allergy 62:207-8. 2007 - Recommendations for standardization of clinical trials with Allergen Specific Immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) taskforceG W Canonica
Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy
Allergy 62:317-24. 2007..This document summarizes the recommendations for study design, patients' selection, appropriate outcomes and statistical treatment to be used in planning and performing clinical trials with specific immunotherapy... - Pattern of use and diagnostic value of complementary/alternative tests for adverse reactions to foodG Senna
Allergy and Respiratory Diseases, Department of Internal Medicine, Padiglione Maragliano, L.go R. Benzi 10, 16132 Genoa, Italy
Allergy 60:1216-7. 2005 - Specific immunotherapy among Italian specialistsC Lombardi
Department of Internal Medicine Padiglione Maragliano, Genoa, Italy
Allergy 61:898-9. 2006 - Safety and pharmacoeconomics of a cluster administration of mite immunotherapy compared to the traditional oneMarina Mauro
S. Anna Hospital, Como
Allerg Immunol (Paris) 38:31-4. 2006..95 euros per patient in the build-up phase. The cluster up-dosing is as safe as the traditional one and allows a significant economical save... - Sensitization to rabbit allergens in Italy--a multicentre study in atopic subjects without occupational exposureGennaro Liccardi
Division of Pneumology and Allergology, Department of Chest Diseases, A. Cardarelli Hospital, Naples, Italy
Int Arch Allergy Immunol 141:295-9. 2006..A progressive increase in rabbit sensitization is expected in the future as consequence of the increased rabbit ownership...