G Parati


Affiliation: University of Milano-Bicocca
Country: Italy


  1. Parati G, Pengo M, Lombardi C. Obstructive Sleep Apnea and Hypertension: Why Treatment Does Not Consistently Improve Blood Pressure. Curr Hypertens Rep. 2019;21:30 pubmed publisher
    ..In addition, greater efforts should be made to improve patient's acceptance of OSA treatment with the aim of improving their compliance. ..
  2. Calvillo L, Gironacci M, Crotti L, Meroni P, Parati G. Neuroimmune crosstalk in the pathophysiology of hypertension. Nat Rev Cardiol. 2019;: pubmed publisher
  3. Parati G, Castiglioni P, Omboni S, Faini A. Effects on 24-hour blood pressure variability of ace-inhibition and calcium channel blockade as monotherapy or in combination. Sci Rep. 2018;8:13779 pubmed publisher
    ..Our study supports a better reduction of BPV by L in the elderly and by E?+?L combination at any age, suggesting BPV reduction to be independent from reduction in average BP. ..
  4. Parati G, Lombardi C, Hedner J, Bonsignore M, Grote L, Tkacova R, et al. Recommendations for the management of patients with obstructive sleep apnoea and hypertension. Eur Respir J. 2013;41:523-38 pubmed publisher
    ..They are also aimed at reminding respiration experts to consider the occurrence of hypertension in patients with respiratory problems at night. ..
  5. Villani A, Malfatto G, Compare A, Della Rosa F, Bellardita L, Branzi G, et al. Clinical and psychological telemonitoring and telecare of high risk heart failure patients. J Telemed Telecare. 2014;20:468-75 pubmed publisher
  6. Caravita S, Faini A, Baratto C, Bilo G, Macarlupu J, Lang M, et al. Upward Shift and Steepening of the Blood Pressure Response to Exercise in Hypertensive Subjects at High Altitude. J Am Heart Assoc. 2018;7: pubmed publisher
    ..The effect of the combination of telmisartan/nifedipine slow release outweighed these changes and was associated with better muscle oxygen delivery. URL: http://www.clinicaltrials.gov. Unique identifier: NCT01830530. ..
  7. Parati G, Bilo G, Faini A, Bilo B, Revera M, Giuliano A, et al. Changes in 24 h ambulatory blood pressure and effects of angiotensin II receptor blockade during acute and prolonged high-altitude exposure: a randomized clinical trial. Eur Heart J. 2014;35:3113-22 pubmed publisher
    ..Ambulatory blood pressure increases progressively with increasing altitude, remaining elevated after 3 weeks. An angiotensin receptor blockade maintains blood pressure-lowering efficacy at 3400 m but not at 5400 m. ..
  8. Caravita S, Faini A, Lombardi C, Valentini M, Gregorini F, Rossi J, et al. Sex and acetazolamide effects on chemoreflex and periodic breathing during sleep at altitude. Chest. 2015;147:120-131 pubmed publisher
    ..EU Clinical Trials Register, EudraCT; No.: 2010-019986-27; URL: https://www.clinicaltrialsregister.eu. ..
  9. Parati G, Ochoa J, Bilo G. Blood pressure variability, cardiovascular risk, and risk for renal disease progression. Curr Hypertens Rep. 2012;14:421-31 pubmed publisher
    ..This review will address whether antihypertensive treatment should target alterations in BPV, in addition to reducing absolute BP levels, in order to achieve the highest CV and renal protection in hypertensive and renal patients. ..

More Information


  1. Lisi E, Faini A, Bilo G, Lonati L, Revera M, Salerno S, et al. Diastolic dysfunction in controlled hypertensive patients with mild-moderate obstructive sleep apnea. Int J Cardiol. 2015;187:686-92 pubmed publisher
    ..Moreover nocturnal hypoxia may be a key factor in determining early diastolic dysfunction, under the synergic effects of hypertension and mild-moderate OSA. ..
  2. Parati G, Omboni S, Albini F, Piantoni L, Giuliano A, Revera M, et al. Home blood pressure telemonitoring improves hypertension control in general practice. The TeleBPCare study. J Hypertens. 2009;27:198-203 pubmed
    ..Patients' management based on home blood pressure teletransmission led to a better control of ambulatory blood pressure than with usual care, with a more regular treatment regimen. ..
  3. Parati G, Malfatto G, Boarin S, Branzi G, Caldara G, Giglio A, et al. Device-guided paced breathing in the home setting: effects on exercise capacity, pulmonary and ventricular function in patients with chronic heart failure: a pilot study. Circ Heart Fail. 2008;1:178-83 pubmed publisher
    ..05). This pilot investigation demonstrates that device-guided paced breathing at home is feasible and results in an improvement in clinically relevant parameters for patients with heart failure and systolic dysfunction. ..
  4. Parati G, Schumacher H, Bilo G, Mancia G. Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database. J Hypertens. 2010;28:2177-83 pubmed publisher
    ..An understanding of the relative effects of different antihypertensives on the smoothness index may help to differentiate their effectiveness in reducing blood pressure-related cardiovascular risk. ..
  5. Hoshide S, Kario K, de la Sierra A, Bilo G, Schillaci G, Banegas J, et al. Ethnic differences in the degree of morning blood pressure surge and in its determinants between Japanese and European hypertensive subjects: data from the ARTEMIS study. Hypertension. 2015;66:750-6 pubmed publisher
  6. Osculati G, Revera M, Branzi G, Faini A, Malfatto G, Bilo G, et al. Effects of hypobaric hypoxia exposure at high altitude on left ventricular twist in healthy subjects: data from HIGHCARE study on Mount Everest. Eur Heart J Cardiovasc Imaging. 2016;17:635-43 pubmed publisher
    ..Our study, for the first time, demonstrates an increase in left ventricular twist at high altitude in healthy subjects exposed to high altitude hypoxia, suggesting the occurrence of subendocardial systolic dysfunction in such condition. ..
  7. Parati G, Ochoa J, Lombardi C, Bilo G. Blood pressure variability: assessment, predictive value, and potential as a therapeutic target. Curr Hypertens Rep. 2015;17:537 pubmed publisher
    ..e., whether routine assessment of BPV in clinical practice should be regarded as an additional target of antihypertensive treatment to improve cardiovascular protection. ..
  8. Parati G, Omboni S. Role of home blood pressure telemonitoring in hypertension management: an update. Blood Press Monit. 2010;15:285-95 pubmed publisher
    ..The role of HBP teletransmission in the context of integrated patients' management programmes is also addressed, with indications for further progress in this field. ..
  9. Bilo G, Villafuerte F, Faini A, Anza Ramírez C, Revera M, Giuliano A, et al. Ambulatory blood pressure in untreated and treated hypertensive patients at high altitude: the High Altitude Cardiovascular Research-Andes study. Hypertension. 2015;65:1266-72 pubmed publisher
    ..URL: http://www.clinicaltrials.gov. Unique identifier: NCT01830530. ..
  10. Castiglioni P, Parati G, Lazzeroni D, Bini M, Faini A, Brambilla L, et al. Hemodynamic and Autonomic Response to Different Salt Intakes in Normotensive Individuals. J Am Heart Assoc. 2016;5: pubmed publisher
    ..Such dysfunction may critically contribute to induce a BP response to dietary salt. ..
  11. Parati G, Bilo G, Redon J. The effects of telmisartan alone or with hydrochlorothiazide on morning and 24-h ambulatory BP control: results from a practice-based study (SURGE 2). Hypertens Res. 2013;36:322-7 pubmed publisher
    ..Only 0.8% (7/863) reported an adverse event. In summary, telmisartan and telmisartan/HCTZ increased smooth 24-h BP control in daily management of hypertension. ..
  12. Parati G, Ochoa J. Automated-auscultatory (Hybrid) sphygmomanometers for clinic blood pressure measurement: a suitable substitute to mercury sphygmomanometer as reference standard?. J Hum Hypertens. 2012;26:211-3 pubmed publisher
  13. Parati G, Stergiou G, Asmar R, Bilo G, De Leeuw P, Imai Y, et al. European Society of Hypertension guidelines for blood pressure monitoring at home: a summary report of the Second International Consensus Conference on Home Blood Pressure Monitoring. J Hypertens. 2008;26:1505-26 pubmed publisher
    ..The final section deals with the problems related to the implementation of these recommendations in clinical practice. ..
  14. Parati G, Ochoa J, Salvi P, Lombardi C, Bilo G. Prognostic value of blood pressure variability and average blood pressure levels in patients with hypertension and diabetes. Diabetes Care. 2013;36 Suppl 2:S312-24 pubmed publisher
  15. Parati G, Torlasco C, Omboni S, Pellegrini D. Smartphone Applications for Hypertension Management: a Potential Game-Changer That Needs More Control. Curr Hypertens Rep. 2017;19:48 pubmed publisher
    ..Results from small studies are promising, but there is a strong need for large, long-term, well-designed clinical trials, before these potential solutions might be reliably applied in real-life patients' care. ..
  16. Torlasco C, Faini A, Makil E, Ferri C, Borghi C, Veglio F, et al. Cardiovascular risk and hypertension control in Italy. Data from the 2015 World Hypertension Day. Int J Cardiol. 2017;243:529-532 pubmed publisher
  17. Revera M, Salvi P, Faini A, Giuliano A, Gregorini F, Bilo G, et al. Renin-Angiotensin-Aldosterone System Is Not Involved in the Arterial Stiffening Induced by Acute and Prolonged Exposure to High Altitude. Hypertension. 2017;70:75-84 pubmed publisher
    ..Renin-angiotensin-aldosterone system does not seem to play any significant role in these hemodynamic changes. URL: https://www.clinicaltrialsregister.eu/. Unique identifier: 2008-000540-14. ..
  18. Parati G, Stergiou G, Asmar R, Bilo G, de Leeuw P, Imai Y, et al. European Society of Hypertension practice guidelines for home blood pressure monitoring. J Hum Hypertens. 2010;24:779-85 pubmed publisher
    ..The present document, which provides concise and updated guidelines on the use of HBPM for practising physicians, was therefore prepared by including the comments and feedback of general practitioners. ..
  19. Parati G, Esler M. The human sympathetic nervous system: its relevance in hypertension and heart failure. Eur Heart J. 2012;33:1058-66 pubmed publisher